Emma Ringqvist
Research Specialist
E-mail: emma.ringqvist@ki.se
Visiting address: Alfred Nobels allé 8, plan 7, 14152 Huddinge
Postal address: H7 Medicin, Huddinge, H7 CIM Flodström-Tullberg, 171 77 Stockholm
About me
- Post-doc in Research group Tim Willinger. Research area: Macrophage ontology,
pulmonary health and injury resolution.
My passion for science and my interest in infection biology, immunology and
the magic world host-parasite interaction has taken me from initial projects
as an undergrad on Hepatitis C replication, virulence factors in /Toxoplasma
gondii/ and /Plasmodium falciparum/ (malaria), a PhD at Uppsala university
on the molecular mechanisms of how the gastrointestinal parasite /Giardia/
establishes infection, to New Zealand and hookworm infections in ruminants
and their effect on the immune system of sheep until I landed in pulmonary
immunology and the development and activities of Alveolar Macrophages. After
a 2-year post doc period in the lab of Professor Judith E. Allen at the
University of Edinburgh, I continued with an independent research line on
emphysema development and injury resolution in the Nippostrongylus
brasiliensis model of COPD, at the Respiratory Medicine unit, Department of
Medicine Solna, Karolinska Institutet. In 2018, I left my independent
research and joined first the Research Group of Åsa Wheelock at the same
department for a postdoctoral project on sorting live monocytes, macrophages
and T-cells from young adult's with known pulmonary limitations due to
premature birth (LUNAPRE cohort). From there I have now started a position at
CIM, Department of Medicine Huddinge, Karolinska Institutet, Research Group
Tim Willinger. My current research project investigate alveolar macrophage
ontology using humanized mice and primary human cells.
2015. Wenner-Gren Research Fellow (2 year salary including research funding)
2010. Wenner-Gren Postdoctoral Fellow (3 year international postdoc).
Application and interview process, 5% success rate.
* 2012-2015. Institute of Immunology and Infection Research, Universtiy of
Edinburgh. Professor Judith E. Allen group. Project: The molecular and
immunological basis of emphysema development in a rodent hookworm model.
* 2010-2012. AgResearch, Palmerston North, New Zealand. Equivalent of 1 year
full time. Project: Immunomodulation of Dendritic Cells by ruminant
helminths.
2009. Scholarship. Lennanders stiftelse. 3 months post-doctoral research
project funding including living cost scholarship.
2010. PhD in Microbiology. Uppsala University. Thesis title: Host-Pathogen
Responses during Giardia infections. Supervisor: Prof. Staffan G. Svärd,
Department of Cell and Molecular Biology.[PMID:16299316]. [1] [PMID:18359106]
[2]. [PMID:21074536]. [3] [PMID:21276445]. [4]
2003. MSc in Molecular Biology. Södertörn University College.
[1] http://www.ncbi.nlm.nih.gov/pubmed/16299316
[2] http://www.ncbi.nlm.nih.gov/pubmed/18359106
[3] http://www.ncbi.nlm.nih.gov/pubmed/21074536
[4] http://www.ncbi.nlm.nih.gov/pubmed/21276445
Research
- I am working on the ontology and activity of human alveolar macrophages in
health and disease (chronic bronchitis and COPD), and foremost in the neonate
life.
During my postdoc (2012-2015) and following couple of years (2015-2018) I
studied the molecular pathways of emphysema formation in the Nippostrongylus
brasiliensis mouse model, and comparing our findings with the molecular
pattern in emphysematic lung tissue of human chronic obstructive pulmonary
disease patients.
Articles
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Article: CELL REPORTS. 2022;38(10):110503
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Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2022;219(2):e20210987
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Article: MUCOSAL IMMUNOLOGY. 2022;15(2):257-267
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Article: IMMUNITY. 2021;54(2):259-275.e7
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Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
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Article: CELL. 2020;183(1):158-168.e14
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Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
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Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
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Article: SCIENCE. 2017;356(6342):1076-1080
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Article: JOURNAL OF INFECTIOUS DISEASES. 2011;204(11):1779-1786
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Article: EXPERIMENTAL PARASITOLOGY. 2011;127(4):804-810
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Article: INTERNATIONAL JOURNAL FOR PARASITOLOGY. 2011;41(3-4):277-285
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Article: MOLECULAR AND BIOCHEMICAL PARASITOLOGY. 2008;159(2):85-91
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Article: INFECTION AND IMMUNITY. 2005;73(12):8204-8208
All other publications
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Review: IMMUNOLOGY. 2020;160(2):126-138
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Review: BIOCHEMICAL PHARMACOLOGY. 2020;174:113672
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Review: NATURE REVIEWS MICROBIOLOGY. 2010;8(6):413-422
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Review: TRENDS IN PARASITOLOGY. 2006;22(1):26-31