I work as a 3R specialist at Swetox, a national research center consisting of eleven Swedish universities, where I am managing our 3R-platform and perform 3R research.
I have a background as a veterinarian, with many years of experience in animal welfare and legislation both from the farm sector and when it comes to ethical use of animals for scientific purposes.
I dissertated in immunology 2002 at the Swedish University of Agriculture on mechanistic research in vitro, ex vivo and in vivo on viral vaccines for pigs and cows. My post doc work was at the Swedish Institute for Infectious Disease Control on mechanism of vaccine memory, linked to the national vaccine program for children in Sweden.
My interest and engagement for translational science (in vitro-in vivo prediction and inter-species extrapolation) and the 3Rs grew further as I was employed at the Safety Assessment unit at AstraZeneca R&D, Södertälje, Sweden. I was involved in the regulatory toxicity testing and risk assessments and responsible for the 3R organisation at the unit, which gave me valuable experience regarding internal development, testing and implementation of 3R-ideas within the research unit and in the frame of regulatory toxicity testing of pharmaceuticals.
PhD in Veterinary Medicine, Swedish University of Agriculture (SLU) 2002
”Effects of Immunostimulatory DNA in the pig – Induction of immunoregulatory cytokines by plasmid DNA, virus or bacteria”
Licensed Veterinarian, D.V.M., Swedish University of Agriculture (SLU) 1995
My research is focused on modern methods for Replacement, Reduction and Refinement of animal-based research models. The principles of the 3Rs means replacing animal models in research with non-animal methods, and increase ethics and scientific quality when animal models are used.
There are two main tracks in my research today: Refinement of research on animal models, and studying 3R awareness in different target groups.
Different types of education / communication activities (lectures, seminars, workshops, group activities for bachelor and master students, laboratory animal facilities (technicians, veterinarians, researchers, mangers) at universities and private organisations, high schools, politicians, authorities.