I am a researcher at the Division of Translational Alzheimer Neurobiology. My goal is to apply brain imaging techniques to the analysis of positron emission tomography (PET) data in Alzheimer patients as well as in a small animal transgenic model.
PhD Nuclear Engineering, University of California, Berkeley, USA (2007)
My research is focused on the analysis of multi-tracer positron emission tomography (PET) imaging and its potential as an early diagnostic tool in Alzheimer's disease. Our group has a special interest in the early role of neuroinflammation and tau deposition in Alzheimer's disease. I am particularly involved in the analysis of PET data to understand the time courses and relationships between astrocytosis, cerebral blood flow, glucose metabolism, amyloid and tau deposition. A deeper understanding of the role of astrocytes in health and disease may open the path to novel therapeutic targets in Alzheimer's disease.
Academic honours, awards and prizes
2013 Young Investigator Award, Human Amyloid Imaging Conference, Miami (USA), January 2013
2013-2014 Wenner-Gren Foundation Postdoctoral Fellowship
2012-2015 Research grants from Alzheimerfonden; Stiftelsen för ålderssjukdomar, Karolinska Institutet; KI Fonder; Gun och Bertil Stohnes Stiftelsen; Ahlén Stiftelsen; Stiftelsen för gamla tjänarinnor; Demensfonden; Loo och Hans Ostermans Stiftelsen
Recent oral presentations:
“Divergent patterns of astrocytosis and fibrilar amyloid plaques as measured by PET in autosomal-dominant and sporadic Alzheimer’s disease”, Alzheimer's Association International Conference (AAIC 2015), July 18-23, 2015, Washington DC, USA
"Comparison of measurements of cerebral blood flow by early frames of 11C-deuterium-L-deprenyl (11C-DED) and 11C-PIB PET tracers at different stages of Alzheimer's disease", Alzheimer Imaging Consortium (AIC), Alzheimer's Association International Conference (AAIC 2014), July 12-17, 2014, Copenhagen, Denmark
"Astrocytosis precedes amyloid deposition in Alzheimer Tg2576 APPswe transgenic mice: A multi-tracer microPET imaging study", Alzheimer's Association International Conference (AAI C2013), July 13-18, 2013, Boston, USA