Eddie Weitzberg

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About me

Eddie Weitzberg is Professor of Anesthesiology and Intensive Care Medicine at the Department of Physiology and Pharmacology.

Articles

Article: BJA OPEN. 2024;9:100256
The effect of heparins on plasma concentration of heparin-binding protein: a pilot study.
Halldorsdottir H; Lindbom L; Ebberyd A; Oldner A; Weitzberg E
Article: SCIENTIFIC REPORTS. 2024;14(1):4025
Antibacterial mouthwash alters gut microbiome, reducing nutrient absorption and fat accumulation in Western diet-fed mice
Carvalho LRRA; Boeder AM; Shimari M; Kleschyov AL; Esberg A; Johansson I; Weitzberg E; Lundberg JO; Carlstrom M
Article: HYPERTENSION. 2023;80(11):2397-2406
Altered Oral Nitrate Reduction and Bacterial Profiles in Hypertensive Women Predict Blood Pressure Lowering Following Acute Dietary Nitrate Supplementation
Willmott T; Ormesher L; Mcbain AJ; Humphreys GJ; Myers JE; Singh G; Lundberg JO; Weitzberg E; Nihlen C; Cottrell EC
Article: NATURE CHEMICAL BIOLOGY. 2023;19(10):1267-1275
NO-ferroheme is a signaling entity in the vasculature
Kleschyov AL; Zhuge Z; Schiffer TA; Guimaraes DD; Zhang G; Montenegro MF; Tesse A; Weitzberg E; Carlstrom M; Lundberg JO
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693
Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP
Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(14):e2212476120
Cholinergic regulation of vascular endothelial function by human ChAT⁺ T cells
Tarnawski L; Shavva VS; Kort EJ; Zhuge Z; Nilsson I; Gallina AL; Martinez-Enguita D; Sahlgren BH; Weiland M; Caravaca AS; Schmidt S; Chen P; Abbas K; Wang F-H; Ahmed O; Eberhardson M; Farnert A; Weitzberg E; Gustafsson M; Kehr J; Malin SG; Hult H; Carlstrom M; Jovinge S; Olofsson PS
Article: REDOX BIOLOGY. 2023;60:102612
Red blood cells from endothelial nitric oxide synthase-deficient mice induce vascular dysfunction involving oxidative stress and endothelial arginase I
Zhuge Z; Haworth SM; Nihlen C; Carvalho LRRA; Heuser SK; Kleschyov AL; Nasiell J; Cortese-Krott MM; Weitzberg E; Lundberg JO; Carlstroem M
Article: REDOX BIOLOGY. 2022;54:102370
Red blood cell eNOS is cardioprotective in acute myocardial infarction
Cortese-Krott MM; Suvorava T; Leo F; Heuser SK; LoBue A; Li J; Becher S; Schneckmann R; Srivrastava T; Erkens R; Wolff G; Schmitt JP; Grandoch M; Lundberg JO; Pernow J; Isakson BE; Weitzberg E; Kelm M
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2022;125:69-77
Downregulation of eNOS and preserved endothelial function in endothelial-specific arginase 1-deficient mice
Heuser SK; LoBue A; Li J; Zhuge Z; Leo F; Suvorava T; Olsson A; Schneckmann R; Braga DDG; Srivrastava T; Montero L; Schmitz OJ; Schmitt JP; Grandoch M; Weitzberg E; Lundberg JO; Pernow J; Kelm M; Carlstrom M; Cortese-Krott MM
Article: NUTRIENTS. 2022;14(12):2480
Plasma Nitrate and Nitrite Kinetics after Single Intake of Beetroot Juice in Adult Patients on Chronic Hemodialysis and in Healthy Volunteers: A Randomized, Single-Blind, Placebo-Controlled, Crossover Study
Heredia-Martinez A; Rosa-Diez G; Ferraris JR; Sohlenius-Sternbeck A-K; Nihlen C; Olsson A; Lundberg JO; Weitzberg E; Carlstrom M; Krmar RT
Article: REDOX BIOLOGY. 2022;51:102266
Inorganic nitrate and nitrite ameliorate kidney fibrosis by restoring lipid metabolism via dual regulation of AMP-activated protein kinase and the AKT-PGC1α pathway
Li X; Zhuge Z; Carvalho LRRA; Braga VA; Lucena RB; Li S; Schiffer TA; Han H; Weitzberg E; Lundberg JO; Carlstrom M
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2022;119:50-60
Cardiovascular characterization of the novel organic mononitrate NDIBP in rats
Cavalcanti ALDM; Rocha PKL; Zhuge Z; Montenegro MF; Paulo LL; Mendes-Junior LDG; Brandao MCR; Athayde-Filho PF; Lundberg JO; Weitsberg E; Carlstrom M; Braga VDA
Article: OTOLOGY & NEUROTOLOGY. 2022;43(2):e198-e204
Nitric Oxide Is Locally Produced in the Human Middle Ear and Is Reduced by Acquired Cholesteatoma
Westerberg J; Granath A; Drakskog C; Tideholm E; Georen SK; Weitzberg E; Cardell L-O
Article: REDOX BIOLOGY. 2021;48:102209
Effects of chronic dietary nitrate supplementation on longevity, vascular function and cancer incidence in rats
Carvalho LRRA; Guimaraes DD; Flor AFL; Leite EG; Ruiz CR; de Andrade JT; Monteiro MMO; Balarini CM; de Lucena RB; Sandrim VC; Lundberg JO; Weitzberg E; Carlstrom M; Braga VDA
Article: BRITISH JOURNAL OF ANAESTHESIA. 2021;127(4):547-555
Effects of inorganic nitrate on ischaemia-reperfusion injury after coronary artery bypass surgery: a randomised controlled trial
Eriksson KE; Eidhagen F; Liska J; Franco-Cereceda A; Lundberg JO; Weitzberg E
Article: CIRCULATION. 2021;144(11):870-889
Red Blood Cell and Endothelial eNOS Independently Regulate Circulating Nitric Oxide Metabolites and Blood Pressure
Leo F; Suvorava T; Heuser SK; Li J; LoBue A; Barbarino F; Piragine E; Schneckmann R; Hutzler B; Good ME; Fernandez BO; Vornholz L; Rogers S; Doctor A; Grandoch M; Stegbauer J; Weitzberg E; Feelisch M; Lundberg JO; Isakson BE; Kelm M; Cortese-Krott MM
Article: JOURNAL OF HYPERTENSION. 2021;39(8):1628-1641
Red blood cells from patients with pre-eclampsia induce endothelial dysfunction
McCann Haworth SM; Zhuge Z; Nihlen C; Von Rosen MF; Weitzberg E; Lundberg JO; Krmar RT; Nasiell J; Carlstrom M
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2021;111:37-44
Multiple-day high-dose beetroot juice supplementation does not improve pulmonary or muscle deoxygenation kinetics of well-trained cyclists in normoxia and hypoxia
Rokkedal-Lausch T; Franch J; Poulsen MK; Thomsen LP; Weitzberg E; Kamavuako EN; Karbing DS; Larsen RG
Article: ACTA PHYSIOLOGICA. 2021;232(1):e13637
Renal handling of nitrate in women and men with elevated blood pressure
Sundqvist ML; Lundberg JO; Weitzberg E; Carlstrom M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2021;22(9):4500
Enhanced Nitrite-Mediated Relaxation of Placental Blood Vessels Exposed to Hypoxia Is Preserved in Pregnancies Complicated by Fetal Growth Restriction
Tropea T; Nihlen C; Weitzberg E; Lundberg JO; Wareing M; Greenwood SL; Sibley CP; Cottrell EC
Article: NATURE AND SCIENCE OF SLEEP. 2021;13:435-446
Effect of Dietary Nitrate Supplementation on Sleep in Chronic Obstructive Pulmonary Disease Patients
Wisor JP; Holmedahl NH; Saxvig IW; Fjeldstad O-M; Weitzberg E; Gronli J; Engan HK
Article: ACTA PHYSIOLOGICA. 2021;231(3):e13581
Germ-free mice are not protected against diet-induced obesity and metabolic dysfunction
Moretti CH; Schiffer TA; Li X; Weitzberg E; Carlstrom M; Lundberg JO
Article: REDOX BIOLOGY. 2021;39:101836
Renovascular effects of inorganic nitrate following ischemia-reperfusion of the kidney
Zhang G; Han H; Zhuge Z; Dong F; Jiang S; Wang W; Guimaraes DD; Schiffer TA; Lai EY; Ribeiro Antonino Carvalho LR; Lucena RB; Braga VA; Weitzberg E; Lundberg JO; Carlstrom M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2020;160:860-870
Dietary nitrite extends lifespan and prevents age-related locomotor decline in the fruit fly
Moretti CH; Schiffer TA; Montenegro MF; Larsen FJ; Tsarouhas V; Carlstrom M; Samakovlis C; Weitzberg E; Lundberg JO
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2020;104:61-69
The new organic nitrate 2-nitrate-1,3-diocthanoxypropan (NDOP) induces nitric oxide production and vasorelaxation via activation of inward-rectifier potassium channels (K_IR)
Bernardino-Paula R; Carvalho-Galva A; Cavalcanti ALM; Rocha PKL; Carvalho LRRA; Brandao MCR; Athayde-Filho PF; Diniz TF; Lemos VS; Franca-Silva MS; Montenegro MF; Weitzberg E; Lundberg JO; Carlstrom M; Braga VA
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2020;598(18):4079-4092
Beetroot juice lowers blood pressure and improves endothelial function in pregnant eNOS^-/- mice: importance of nitrate-independent effects
Tropea T; Renshall LJ; Nihlen C; Weitzberg E; Lundberg JO; David AL; Tsatsaris V; Stuckey DJ; Wareing M; Greenwood SL; Sibley CP; Cottrell EC
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2020;98:33-40
"Removal of nitrate and nitrite by hemodialysis in end-stage renal disease and by sustained low-efficiency dialysis in acute kidney injury"
Heredia Martinez A; Rosa Diez G; Ferraris V; Coccia PA; Ferraris JR; Checa A; Wheelock CE; Lundberg JO; Weitzberg E; Carlstrom M; Krmar RT
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2020;111(4):749-756
A randomized clinical trial of the effects of leafy green vegetables and inorganic nitrate on blood pressure
Sundqvist ML; Larsen FJ; Carlstrom M; Bottai M; Pernow J; Hellenius M-L; Weitzberg E; Lundberg JO
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2020;97:48-56
Head-to-head comparison of inorganic nitrate and metformin in a mouse model of cardiometabolic disease
Cordero-Herrera I; Guimaraes DD; Moretti C; Zhuge Z; Han H; Haworth SM; Gonzalez AEU; Andersson DC; Weitzberg E; Lundberg JO; Carlstrom M
Article: REDOX BIOLOGY. 2020;28:101387
Dietary nitrate attenuates high-fat diet-induced obesity via mechanisms involving higher adipocyte respiration and alterations in inflammatory status
Peleli M; Ferreira DMS; Tarnawski L; Haworth SM; Xuechen L; Zhuge Z; Newton PT; Massart J; Chagin AS; Olofsson PS; Ruas JL; Weitzberg E; Lundberg JO; Carlstrom M
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2020;94:73-78
Effects of age, sex and diet on salivary nitrate and nitrite in infants
Timby N; Domellof M; Hernell E; Lonnerdal B; Nihlen C; Johanssson I; Weitzberg E
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2019;145:342-348
The obligatory role of host microbiota in bioactivation of dietary nitrate
Moretti C; Zhuge Z; Zhang G; Haworth SM; Paulo LL; Guimaraes DD; Cruz JC; Montenegro MF; Cordero-Herrera I; Braga VA; Weitzberg E; Carlstrom M; Lundberg JO
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2019;85:44-52
Chronic high-dose beetroot juice supplementation improves time trial performance of well-trained cyclists in normoxia and hypoxia
Rokkedal-Lausch T; Franch J; Poulsen MK; Thomsen LP; Weitzberg E; Kamavuako EN; Karbing DS; Larsen RG
Article: HYPERTENSION. 2019;73(4):839-848
Dietary Nitrate Reduces Blood Pressure in Rats With Angiotensin II-Induced Hypertension via Mechanisms That Involve Reduction of Sympathetic Hyperactivity
Guimaraes DD; Cruz JC; Carvalho-Galvao A; Zhuge Z; Marques SM; Naves LM; Persson AEG; Weitzberg E; Lundberg JO; Balarini CM; Pedrino GR; Braga VA; Carlstrom M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(1):217-226
AMP-activated protein kinase activation and NADPH oxidase inhibition by inorganic nitrate and nitrite prevent liver steatosis
Cordero-Herrera I; Kozyra M; Zhuge Z; Haworth SM; Moretti C; Peleli M; Caldeira-Dias M; Jahandideh A; Han H; Cruz JDC; Kleschyov AL; Montenegro MF; Ingelman-Sundberg M; Weitzberg E; Lundberg JO; Carlstrom M
Article: NEUROIMAGE-CLINICAL. 2019;24:101955
APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan
Rasmussen PM; Aamand R; Weitzberg E; Christiansen M; Ostergaard L; Lund TE
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2018;80:37-44
Effects of dietary nitrate supplementation, from beetroot juice, on blood pressure in hypertensive pregnant women: A randomised, double-blind, placebo-controlled feasibility trial
Ormesher L; Myers JE; Chmiel C; Wareing M; Greenwood SL; Tropea T; Lundberg JO; Weitzberg E; Nihlen C; Sibley CP; Johnstone ED; Cottrell EC
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2018;62(7):962-973
Heparin-binding protein as a biomarker of post-injury sepsis in trauma patients
Halldorsdottir HD; Eriksson J; Persson BP; Herwald H; Lindbom L; Weitzberg E; Oldner A
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2018;75:16-26
Organ uptake and release of inorganic nitrate and nitrite in the pig
Eriksson KE; Yang T; Carlstrom M; Weitzberg E
Article: SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS. 2017;27(12):1616-1626
Effects of nitrate supplementation in trained and untrained muscle are modest with initial high plasma nitrite levels
Christensen PM; Petersen NK; Friis SN; Weitzberg E; Nybo L
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2017;70:1-8
Physiological and performance effects of nitrate supplementation during roller-skiing in normoxia and normobaric hypoxia
Nyback L; Glannerud C; Larsson G; Weitzberg E; Shannon OM; McGawley K
Article: REDOX BIOLOGY. 2017;13:320-330
Dietary nitrate attenuates renal ischemia-reperfusion injuries by modulation of immune responses and reduction of oxidative stress
Yang T; Zhang X-M; Tarnawski L; Peleli M; Zhuge Z; Terrando N; Harris RA; Olofsson PS; Larsson E; Persson AEG; Lundberg JO; Weitzberg E; Carlstrom M
Article: HYPERTENSION. 2017;69(1):23-31
Blood Pressure-Lowering Effect of Orally Ingested Nitrite Is Abolished by a Proton Pump Inhibitor
Montenegro MF; Sundqvist ML; Larsen FJ; Zhuge Z; Carlstrom M; Weitzberg E; Lundberg JO
Article: PHYSIOLOGY & BEHAVIOR. 2017;168:55-61
Dietary nitrate markedly improves voluntary running in mice
Ivarsson N; Schiffer TA; Hernandez A; Lanner JT; Weitzberg E; Lundberg JO; Westerblad H
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2016;61:38-44
Effects of antiseptic mouthwash on resting metabolic rate: A randomized, double-blind, crossover study
Sundqvist ML; Lundberg JO; Weitzberg E
Article: REDOX BIOLOGY. 2016;10:206-210
Profound differences between humans and rodents in the ability to concentrate salivary nitrate: Implications for translational research
Montenegro MF; Sundqvist ML; Nihlen C; Hezel M; Carlstrom M; Weitzberg E; Lundberg JO
Article: REDOX BIOLOGY. 2016;10:119-127
Nitrite-mediated reduction of macrophage NADPH oxidase activity is dependent on xanthine oxidoreductase-derived nitric oxide but independent of S-nitrosation
Zollbrecht C; Persson AEG; Lundberg JO; Weitzberg E; Carlstrom M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2016;99:472-484
Enhanced XOR activity in eNOS-deficient mice Effects on the nitrate-nitrite-NO pathway and ROS homeostasis
Peleli M; Zollbrecht C; Montenegro MF; Hezel M; Zhong J; Persson EG; Holmdahl R; Weitzberg E; Lundberg JO; Carlstrom M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2016;99:87-98
Dietary nitrate improves age-related hypertension and metabolic abnormalities in rats via modulation of angiotensin II receptor signaling and inhibition of superoxide generation
Hezel M; Peleli M; Liu M; Zollbrecht C; Jensen BL; Checa A; Giulietti A; Wheelock CE; Lundberg JO; Weitzberg E; Carlstrom M
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2016;311(3):C452-C461
Control of human energy expenditure by cytochrome c oxidase subunit IV-2
Schiffer TA; Peleli M; Sundqvist ML; Ekblom B; Lundberg JO; Weitzberg E; Larsen FJ
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2016;58:1-9
Peritoneal dialysis impairs nitric oxide homeostasis and may predispose infants with low systolic blood pressure to cerebral ischemia
Carlstrom M; Cananau C; Checa A; Wide K; Sartz L; Svensson A; Wheelock CE; Westphal S; Bekassy Z; Barany P; Lundberg JO; Hansson S; Weitzberg E; Krmar RT
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2016;173(14):2290-2302
Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II-mediated hypertension
Porpino SKP; Zollbrecht C; Peleli M; Montenegro MF; Brandao MCR; Athayde-Filho PF; Franca-Silva MS; Larsson E; Lundberg JO; Weitzberg E; Persson EG; Braga VA; Carlstrom M
Article: BASIC RESEARCH IN CARDIOLOGY. 2016;111(3):34
Dietary nitrate improves cardiac contractility via enhanced cellular Ca²⁺ signaling
Pironti G; Ivarsson N; Yang J; Farinotti AB; Jonsson W; Zhang S-J; Bas D; Svensson CI; Westerblad H; Weitzberg E; Lundberg JO; Pernow J; Lanner J; Andersson DC
Article: LOGOPEDICS PHONIATRICS VOCOLOGY. 2016;41(1):33-40
Eliminating paranasal sinus resonance and its effects on acoustic properties of the nasal tract
Havel M; Kornes T; Weitzberg E; Lundberg JO; Sundberg J
Article: REDOX BIOLOGY. 2015;5:234-242
Effects of long-term dietary nitrate supplementation in mice
Hezel MP; Liu M; Schiffer TA; Larsen FJ; Checa A; Wheelock CE; Carlstrom M; Lundberg JO; Weitzberg E
Article: ANTIOXIDANTS & REDOX SIGNALING. 2015;23(4):295-306
Cross-talk Between Nitrate-Nitrite-NO and NO Synthase Pathways in Control of Vascular NO Homeostasis
Carlstrom M; Liu M; Yang T; Zollbrecht C; Huang L; Peleli M; Borniquel S; Kishikawa H; Hezel M; Persson AEG; Weitzberg E; Lundberg JO
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2015;84:154-160
Nitrite-mediated renal vasodilatation is increased during ischemic conditions via cGMP-independent signaling
Liu M; Zollbrecht C; Peleli M; Lundberg JO; Weitzberg E; Carlstrom M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2015;83:159-166
Inorganic nitrite attenuates NADPH oxidase-derived superoxide generation in activated macrophages via a nitric oxide-dependent mechanism
Yang T; Peleli M; Zollbrecht C; Giulietti A; Terrando N; Lundberg JO; Weitzberg E; Carlstrom M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2015;80:121-128
Interactions between cocoa flavanols and inorganic nitrate: Additive effects on endothelial function at achievable dietary amounts
Rodriguez-Mateos A; Hezel M; Aydin H; Kelm M; Lundberg JO; Weitzberg E; Spencer JPE; Heiss C
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2015;44:88-97
Effects of hyperbaric oxygen on nitric oxide generation in humans
Uusijarvi J; Eriksson K; Larsson AC; Nihlen C; Schiffer T; Lindholm P; Weitzberg E
Article: DRUG DESIGN DEVELOPMENT AND THERAPY. 2015;9:2409-2419
Ultrasound contrast agent loaded with nitric oxide as a theranostic microdevice
Grishenkov D; Gonon A; Weitzberg E; Lundberg JO; Harmark J; Cerroni B; Paradossi G; Janerot-Sjoberg B
Article: FRONTIERS IN PHYSIOLOGY. 2015;6:222
In adenosine A_2B knockouts acute treatment with inorganic nitrate improves glucose disposal, oxidative stress, and AMPK signaling in the liver
Peleli M; Hezel M; Zollbrecht C; Persson AEG; Lundberg JO; Weitzberg E; Fredholm BB; Carlstrom M
Article: HYPERTENSION. 2015;65(1):161-170
NADPH Oxidase in the Renal Microvasculature Is a Primary Target for Blood Pressure-Lowering Effects by Inorganic Nitrate and Nitrite
Gao X; Yang T; Liu M; Peleli M; Zollbrecht C; Weitzberg E; Lundberg JO; Persson AEG; Carlstrom M
Article: FASEB JOURNAL. 2014;28(10):4303-4311
Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans
Schiffer TA; Ekblom B; Lundberg JO; Weitzberg E; Larsen FJ
Article: CRITICAL CARE. 2014;18(5):488
Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep
Fenhammar J; Rundgren M; Hultenby K; Forestier J; Taavo M; Kenne E; Weitzberg E; Eriksson S; Ozenci V; Wernerson A; Frithiof R
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2014;58(5):549-559
Heparin-binding protein (HBP/CAP37) - a link to endothelin-1 in endotoxemia-induced pulmonary oedema?
Persson BP; Halldorsdottir H; Lindbom L; Rossi P; Herwald H; Weitzberg E; Oldner A
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2014;99(4):843-850
Dietary nitrate reduces resting metabolic rate: a randomized, crossover study in humans
Larsen FJ; Schiffer TA; Ekblom B; Mattsson MP; Checa A; Wheelock CE; Nystrom T; Lundberg JO; Weitzberg E
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2013;65:1257-1264
Control of pathogen growth and biofilm formation using a urinary catheter that releases antimicrobial nitrogen oxides
Kishikawa H; Ebberyd A; Romling U; Brauner A; Luthje P; Lundberg JO; Weitzberg E
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2013;57(5):580-586
Heparin-binding protein (HBP): an early marker of respiratory failure after trauma?
Johansson J; Brattstrom O; Sjoberg F; Lindbom L; Herwald H; Weitzberg E; Oldner A
Article: GUT. 2013;62(4):616-629
Biology of nitrogen oxides in the gastrointestinal tract
Lundberg JO; Weitzberg E
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2013;55:93-100
Physiological role for nitrate-reducing oral bacteria in blood pressure control
Kapil V; Haydar SMA; Pearl V; Lundberg JO; Weitzberg E; Ahluwalia A
Article: RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY. 2013;185(2):339-348
Effects of dietary inorganic nitrate on static and dynamic breath-holding in humans
Schiffer TA; Larsen FJ; Lundberg JO; Weitzberg E; Lindholm P
Article: JOURNAL OF NEUROTRAUMA. 2012;29(17):2613-2624
Multivariate Outcome Prediction in Traumatic Brain Injury with Focus on Laboratory Values
Nelson DW; Rudehill A; MacCallum RM; Holst A; Wanecek M; Weitzberg E; Bellander B-M
Article: CIRCULATION. 2012;126(16):1983-1992
Dietary Nitrate Supplementation Improves Revascularization in Chronic Ischemia
Hendgen-Cotta UB; Luedike P; Totzeck M; Kropp M; Schicho A; Stock P; Rammos C; Niessen M; Heiss C; Lundberg JO; Weitzberg E; Kelm M; Rassaf T
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2012;53(5):1017-1023
Inorganic nitrite stimulates pancreatic islet blood flow and insulin secretion
Nystrom T; Ortsater H; Huang Z; Zhang F; Larsen FJ; Weitzberg E; Lundberg JO; Sjoholm A
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2012;590(15):3575-3583
Dietary nitrate increases tetanic [Ca2+]i and contractile force in mouse fast-twitch muscle
Hernandez A; Schiffer TA; Ivarsson N; Cheng AJ; Bruton JD; Lundberg JO; Weitzberg E; Westerblad H
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2012;52(9):1767-1772
Dietary inorganic nitrate mobilizes circulating angiogenic cells
Heiss C; Meyer C; Totzeck M; Hendgen-Cotta UB; Heinen Y; Luedike P; Keymel S; Ayoub N; Lundberg JO; Weitzberg E; Kelm M; Rassaf T
Article: FASEB JOURNAL. 2011;25(8):2843-2852
Mitochondrial oxygen affinity predicts basal metabolic rate in humans
Larsen FJ; Schiffer TA; Sahlin K; Ekblom B; Weitzberg E; Lundberg JO
Article: BMC MEDICINE. 2011;9:21
Analyses of cerebral microdialysis in patients with traumatic brain injury: relations to intracranial pressure, cerebral perfusion pressure and catheter placement
Nelson DW; Thornquist B; MacCallum RM; Nystrom H; Holst A; Rudehill A; Wanecek M; Bellander B-M; Weitzberg E
Article: CARDIOVASCULAR RESEARCH. 2011;89(3):574-585
Dietary nitrate attenuates oxidative stress, prevents cardiac and renal injuries, and reduces blood pressure in salt-induced hypertension
Carlstrom M; Persson AEG; Larsson E; Hezel M; Scheffer PG; Teerlink T; Weitzberg E; Lundberg JO
Article: CELL METABOLISM. 2011;13(2):149-159
Dietary Inorganic Nitrate Improves Mitochondrial Efficiency in Humans
Larsen FJ; Schiffer TA; Borniquel S; Sahlin K; Ekblom B; Lundberg JO; Weitzberg E
Article: PLOS ONE. 2011;6(7):e21534
Endothelin Receptor A Antagonism Attenuates Renal Medullary Blood Flow Impairment in Endotoxemic Pigs
Fenhammar J; Andersson A; Forestier J; Weitzberg E; Sollevi A; Hjelmqvist H; Frithiof R
Article: BRITISH JOURNAL OF ANAESTHESIA. 2010;105(5):640-647
Endothelin-mediated gut microcirculatory dysfunction during porcine endotoxaemia
Andersson A; Fenhammar J; Weitzberg E; Sollevi A; Hjelmqvist H; Frithiof R
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(41):17716-17720
Dietary inorganic nitrate reverses features of metabolic syndrome in endothelial nitric oxide synthase-deficient mice
Carlstrom M; Larsen FJ; Nystrom T; Hezel M; Borniquel S; Weitzberg E; Lundberg JO
Article: JOURNAL OF TRAUMA. 2010;69(4):741-748
Effects of Fluid Resuscitation With Hypertonic Saline Dextrane or Ringer's Acetate After Nonhemorrhagic Shock Caused By Pulmonary Contusion
Gryth D; Rocksen D; Drobin D; Druid H; Weitzberg E; Bursell J; Olsson L-G; Arborelius UP
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2010;396(1):39-45
NO-synthase independent NO generation in mammals
Lundberg JO; Weitzberg E
Article: NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL. 2010;62(4):501-504
Inhibition of Cancer Cell Replication by Inorganic Nitrite
Morcos E; Carlsson S; Weitzberg E; Wiklund NP; Lundberg JO
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2010;48(2):342-347
Dietary nitrate reduces maximal oxygen consumption while maintaining work performance in maximal exercise
Larsen FJ; Weitzberg E; Lundberg JO; Ekblom B
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2010;108(1):181-188
Nasal nitric oxide and regulation of human pulmonary blood flow in the upright position
Crespo AS; Hallberg J; Lundberg JO; Lindahl SGE; Jacobsson H; Weitzberg E; Nyren S
Article: JOURNAL OF NEUROTRAUMA. 2010;27(1):51-64
Extended Analysis of Early Computed Tomography Scans of Traumatic Brain Injured Patients and Relations to Outcome
Nelson DW; Nystrom H; MacCallum RM; Thornquist B; Lilja A; Bellander B-M; Rudehill A; Wanecek M; Weitzberg E
Article: NATURE CHEMICAL BIOLOGY. 2009;5(12):865-869
Nitrate and nitrite in biology, nutrition and therapeutics
Lundberg JO; Gladwin MT; Ahluwalia A; Benjamin N; Bryan NS; Butler A; Cabrales P; Fago A; Feelisch M; Ford PC; Freeman BA; Frenneaux M; Friedman J; Kelm M; Kevil CG; Kim-Shapiro DB; Kozlov AV; Lancaster JRJ; Lefer DJ; McColl K; McCurry K; Patel RP; Petersson J; Rassaf T; Reutov VP; Richter-Addo GB; Schechter A; Shiva S; Tsuchiya K; van Faassen EE; Webb AJ; Zuckerbraun BS; Zweier JL; Weitzberg E
Article: SHOCK. 2009;32(4):427-434
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Persson BP; Rossi P; Weitzberg E; Oldner A
Article: ACTA PHYSIOLOGICA. 2009;196(4):375-383
Left ventricular mechanical dyssynchrony is load independent at rest and during endotoxaemia in a porcine model
A'roch R; Steendijk P; Oldner A; Weitzberg E; Konrad D; Johansson G; Haney M
Article: ARCHIVES OF PHARMACAL RESEARCH. 2009;32(8):1119-1126
NO Generation from Inorganic Nitrate and Nitrite: Role in Physiology, Nutrition and Therapeutics
Lundberg JO; Weitzberg E
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2008;19(4):333-337
The increase in plasma nitrite after a dietary nitrate load is markedly attenuated by an antibacterial mouthwash
Govoni M; Jansson EA; Weitzberg E; Lundberg JO
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2008;52(10):1385-1393
The endothelin receptor antagonist tezosentan improves renal microcirculation in a porcine model of endotoxemic shock
Fenhammar J; Andersson A; Frithiof R; Forestier J; Weitzberg E; Sollevi A; Hjelmqvist H
Article: JOURNAL OF SURGICAL RESEARCH. 2008;149(1):138-147
Mixed endothelin receptor antagonism with tezosentan improves intestinal microcirculation in endotoxemic shock
Andersson A; Fenhammar J; Frithiof R; Weitzberg E; Sollevi A; Hjelmqvist H
Article: PULMONARY PHARMACOLOGY & THERAPEUTICS. 2008;21(4):689-693
Exhaled nitric oxide monitoring in COPD using a portable analyzer
de Laurentiis G; Maniscalco M; Cianciulli F; Stanziola A; Marsico S; Lundberg JO; Weitzberg E; Sofia M
Journal article: NATURE REVIEWS DRUG DISCOVERY. 2008;7(8):710
Downsides to the nitrate–nitrite–nitric oxide pathway in physiology and therapeutics?
Panesar NS
Journal article: NATURE REVIEWS DRUG DISCOVERY. 2008;7(8):710
Downsides to the nitrate-nitrite-nitric oxide pathway in physiology and therapeutics?
Panesar NS
Journal article: NATURE REVIEWS DRUG DISCOVERY. 2008;7(8):710
Downsides to the nitrate-nitrite-nitric oxide pathway in physiology and therapeutics?
Panesar NS
Article: NATURE CHEMICAL BIOLOGY. 2008;4(7):411-417
A mammalian functional nitrate reductase that regulates nitrite and nitric oxide homeostasis
Jansson EA; Huang L; Malkey R; Govoni M; Nihlen C; Olsson A; Stensdotter M; Petersson J; Holm L; Weitzberg E; Lundberg JO
Article: INTENSIVE CARE MEDICINE. 2008;34(5):873-880
Endotoxemic pulmonary hypertension is largely mediated by endothelin-induced venous constriction
Rossi P; Persson B; Boels PJM; Arner A; Weitzberg E; Oldner A
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2008;38(3):197-200
Validation study of nasal nitric oxide measurements using a hand-held electrochemical analyser
Maniscalco M; de Laurentiis G; Weitzberg E; Lundberg JO; Sofia M
Article: ACTA PHYSIOLOGICA. 2007;191(1):59-66
Effects of dietary nitrate on oxygen cost during exercise
Larsen FJ; Weitzberg E; Lundberg JO; Ekblom B
Article: ACTA PHYSIOLOGICA. 2007;190(4):291-302
Effects of the dual endothelin receptor antagonist tezosentan and hypertonic saline/dextran on porcine endotoxin shock
Somell A; Weitzberg E; Suneson A; Sollevi A; Hjelmqvist H
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2007;293(2):H988-H996
Cardiac effects of endothelin receptor antagonism in endotoxemic pigs
Konrad D; Haney M; Johansson G; Wanecek M; Weitzberg E; Oldner A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2007;42(4):510-518
Protection from nonsteroidal anti-inflammatory drug (NSAID)-induced gastric ulcers by dietary nitrate
Jansson EA; Petersson J; Reinders C; Sobko T; Bjorne H; Phillipson M; Weitzberg E; Holm L; Lundberg JO
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2006;15(4):359-362
Cardioprotective effects of vegetables:: Is nitrate the answer?
Lundberg JO; Feelisch M; Bjorne H; Jansson EA; Weitzberg E
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2006;41(9):1404-1412
Intragastric generation of antimicrobial nitrogen oxides from saliva -: Physiological and therapeutic considerations
Bjorne H; Weitzberg E; Lundberg JO
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2006;36(7):509-513
Sounding airflow enhances aerosol delivery into the paranasal sinuses
Maniscalco M; Sofia M; Weitzberg E; Lundberg JO
Article: JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA. 2006;20(3):311-314
Wedging the pulmonary artery catheter:: Changes in left atrial and pulmonary artery pressures and risk for perforation
Settergren G; Angdin M; Anderson RE; Liska J; Lundberg J; Törnberg DC; Weitzberg E
Article: CRITICAL CARE MEDICINE. 2006;34(5):1437-1443
Comparison of a single indicator and gravimetric technique for estimation of extravascular lung water in endotoxemic pigs
Rossi P; Wanecek M; Rudehill A; Konrad D; Weitzberg E; Oldner A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2005;289(4):H1702-H1709
Positive inotropic and negative lusitropic effects of endothelin receptor agonism in vivo
Konrad D; Oldner A; Wanecek M; Rudehill A; Weitzberg E; Biber B; Johansson G; Häggmark S; Haney M
Article: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. 2005;3(8):777-783
Rectal mucosal nitric oxide in differentiation of inflammatory bowel disease and irritable bowel syndrome
Reinders CI; Herulf M; Ljung T; Hollenberg J; Weitzberg E; Lundberg JO; Hellström PM
Article: CRITICAL CARE MEDICINE. 2005;33(8):1722-1727
Intragastric nitric oxide is abolished in intubated patients and restored by nitrite
Björne H; Govoni M; Törnberg DC; Lundberg JO; Weitzberg E
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2005;49(6):2352-2355
Intravesical nitric oxide delivery for prevention of catheter-associated urinary tract infections
Carlsson S; Weitzberg E; Wiklund P; Lundberg JO
Article: THORAX. 2005;60(3):219-225
Origin of nitrite and nitrate in nasal and exhaled breath condensate and relation to nitric oxide formation
Marteus H; Törnberg DC; Weitzberg E; Schedin U; Alving K
Article: BRITISH JOURNAL OF ANAESTHESIA. 2005;94(2):174-180
Exhaled nitric oxide before and after cardiac surgery with cardiopulmonary bypass-response to acetylcholine and nitroglycerin
Törnberg DC; Angdin M; Settergen G; Liska J; Lundberg JO; Weitzberg E
Article: CRITICAL CARE MEDICINE. 2004;32(12):2428-2436
Cerebral microdialysis of patients with severe traumatic brain injury exhibits highly individualistic patterns as visualized by cluster analysis with self-organizing maps
Nelson DW; Bellander BM; MacCallum RM; Axelsson J; Alm M; Wallin M; Weitzberg E; Rudehill A
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2004;34(8):555-560
Humming-induced release of nasal nitric oxide for assessment of sinus obstruction in allergic rhinitis: pilot study
Maniscalco M; Sofia M; Weitzberg E; de Laurentiis G; Stanziola A; Rossillo V; Lundberg JO
Article: CRITICAL CARE MEDICINE. 2004;32(5):1192-1199
Differentiated and dose-related cardiovascular effects of a dual endothelin receptor antagonist in endotoxin shock
Konrad D; Oldner A; Rossi P; Wanecek M; Rudehill A; Weitzberg E
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2004;11(2):250-254
Rectal nitric oxide gas and stool cytokine levels during the course of infectious gastroenteritis
Enocksson A; Lundberg J; Weitzberg E; Norrby-Teglund A; Svenungsson B
Article: SUPPORTIVE CARE IN CANCER. 2004;12(2):99-105
Totally implantable subcutaneous port system versus central venous catheter placed before induction chemotherapy in patients with acute leukaemia -: a randomized study
Johansson E; Björkholm M; Björvell H; Hast R; Takolander R; Olofsson P; Backman L; Weitzberg E; Engervall P
Article: BRITISH JOURNAL OF DERMATOLOGY. 2004;150(2):259-266
The density of epidermal p53 clones is higher adjacent to squamous cell carcinoma in comparison with basal cell carcinoma
Bäckvall H; Wolf O; Hermelin H; Weitzberg E; Pontén F
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2004;48(1):74-81
Complement activation, endothelin-1 and neuropeptide Y in relation to the cardiovascular response to endotoxin-induced systemic inflammation in healthy volunteers
Soop A; Albert J; Weitzberg E; Bengtsson A; Lundberg JON; Sollevi A
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2004;39(1):32-36
Effect of intravenous L-NMMA on nitric oxide production in collagenous colitis
Reinders CI; Hellström PM; Björk J; Weitzberg E; Lundberg JO
Article: JOURNAL OF CLINICAL INVESTIGATION. 2004;113(1):106-114
Nitrite in saliva increases gastric mucosal blood flow and mucus thickness
Björne H; Petersson J; Phillipson M; Weltzberg E; Holm L; Lundberg JO
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;135(1):114-118
Nicotinamide does not influence cytokines or exhaled NO in human experimental endotoxaemia
Soop A; Albert J; Weitzberg E; Bengtsson A; Nilsson CG; Sollevi A
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2003;47(12):3713-3718
In vitro evaluation of a new treatment for urinary tract infections caused by nitrate-reducing bacteria
Carlsson S; Govoni M; Wiklund NP; Weitzberg E; Lundberg JO
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2003;33(12):1090-1094
Nasal nitric oxide measurements before and after repeated humming maneuvers
Maniscalco M; Sofia M; Weitzberg E; Carratu L; Lundberg JON
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2003;168(10):1210-1215
Multiple single-breath measurements of nitric oxide in the intubated patient
Törnberg DC; Björne H; Lundberg JO; Weitzberg E
Article: EUROPEAN RESPIRATORY JOURNAL. 2003;22(2):323-329
Assessment of nasal and sinus nitric oxide output using single-breath humming exhalations
Maniscalco M; Weitzberg E; Sundberg J; Sofia M; Lundberg JO
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2003;168(1):114-120
Endogenous nitric oxide release by vasoactive drugs monitored in exhaled air
Malmström RE; Törnberg DC; Settergren G; Liska J; Angdin M; Lundberg JO; Weitzberg E
Article: EUROPEAN RESPIRATORY JOURNAL. 2003;21(4):594-599
Exhaled NO and plasma cGMP increase after endotoxin infusion in healthy volunteers
Soop A; Sollevi A; Weitzberg E; Lundberg JON; Palm J; Albert J
Article: INTENSIVE CARE MEDICINE. 2003;29(3):460-466
Comparison of gravimetric and a double-indicator dilution technique for assessment of extra-vascular lung water in endotoxaemia
Rossi P; Oldner A; Wanecek M; Leksell LG; Rudehill A; Konrad D; Weitzberg E
Article: SHOCK. 2002;18(5):456-460
Intestinal nitric oxide in the normal and endotoxemic pig
Malmström RE; Björne H; Oldner A; Wanecek M; Fredriksson M; Lundberg JON; Weitzberg E
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2002;93(5):1608-1615
Endothelin-induced vascular and bronchial effects in pig airways: role in acute allergic responses
Sylvin H; Weitzberg E; Alving K
Article: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2002;166(2):144-145
Humming greatly increases nasal nitric oxide
Weitzberg E; Lundberg JON
Article: JOURNAL OF NEUROTRAUMA. 2002;19(7):855-868
Outcome of traumatic brain injuries in 1,508 patients: Impact of prehospital care
Rudehill A; Bellander BM; Weitzberg E; Bredbacka S; Backheden M; Gordon E
Article: EUROPEAN RESPIRATORY JOURNAL. 2002;19(5):859-864
Nasal and oral contribution to inhaled and exhaled nitric oxide:: a study in tracheotomized patients
Törnberg DCF; Marteus H; Schedin U; Alving K; Lundberg JON; Weitzberg E
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2002;439(1-3):113-119
Autoinhibitory function of the sympathetic prejunctional neuropeptide YY₂ receptor evidenced by BIIE0246
Malmström RE; Lundberg JON; Weitzberg E
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2002;34(3):302-306
Increased rectal nitric oxide in children with active inflammatory bowel disease
Ljung T; Beijer E; Herulf M; Weitzberg E; Lundberg JON; Finkel Y; Hellström PM
Article: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY. 2002;365(2):106-111
Effects of the neuropeptide YY2 receptor antagonist BIIE0246 on sympathetic transmitter release in the pig in vivo
Malmström RE; Lundberg JON; Weitzberg E
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2001;5(6):580-586
Effects of pH, nitrite, and ascorbic acid on nonenzymatic nitric oxide generation and bacterial growth in urine
Carlsson S; Wiklund NP; Engstrand L; Weitzberg E; Lundberg JON
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2001;45(10):1262-1270
Effects of the endothelin receptor antagonist bosentan on cardiac performance during porcine endotoxin shock
Wanecek M; Weitzberg E; Alving K; Rudehill A; Oldner A
Article: CRITICAL CARE MEDICINE. 2001;29(11):2185-2193
Effects of levosimendan, a novel inotropic calcium-sensitizing drug, in experimental septic shock
Oldner A; Konrad D; Weitzberg E; Rudehill A; Rossi P; Wanecek M
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2001;45(6):710-719
Risk factors for nosocomial intensive care infection:: a long-term prospective analysis
Appelgren P; Hellström I; Weitzberg E; Söderlund V; Bindslev L; Ransjö U
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2001;5(2):98-104
Nitric oxide inhibition of renal vasoconstrictor responses to sympathetic cotransmitters in the pig in vivo
Malmström RE; Bjorne H; Alving K; Weitzberg E; Lundberg JON
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2001;36(2):169-173
Increased rectal nitric oxide in coeliac disease after local challenge with gluten
Herulf M; Blomquist L; Ljung T; Weitzberg E; Lundberg JON
Article: ACTA PHYSIOLOGICA. 2001;171(1):9-16
Nitrite-derived nitric oxide:: a possible mediator of 'acidic-metabolic' vasodilation
Modin A; Björne H; Herulf M; Alving K; Weitzberg E; Lundberg JON
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1999;386(2-3):235-245
Effects on haemodynamics by selective endothelin ET_B receptor and combined endothelin ET_A/ET_B receptor antagonism during endotoxin shock
Wanecek M; Oldner A; Sundin P; Alving K; Weitzberg E; Rudehill A
Article: SHOCK. 1999;12(5):382-390
Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production
Middelveld RJM; Wanecek M; Bergman D; Weitzberg E; Alving K
Article: THORAX. 1999;54(10):947-952
Nasal nitric oxide in man
Lundberg JON; Weitzberg E
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1999;127(8):1793-1804
Differentiated effects on splanchnic homeostasis by selective and non-selective endothelin receptor antagonism in porcine endotoxaemia
Oldner A; Wanecek M; Weitzberg E; Sundin P; Sollevi A; Rubio C; Hellström PM; Alving K; Rudehill A
Article: JOURNAL OF INFECTIOUS DISEASES. 1999;180(2):542-545
Increased nitric oxide in infective gastroenteritis
Herulf M; Svenungsson B; Lagergren Å; Ljung T; Morcos E; Wiklund NP; Lundberg JON; Weitzberg E
Article: RESPIRATORY MEDICINE. 1999;93(2):134-135
Nostril widening improves arterial oxygenation: a role for nasal nitric oxide?
Herulf M; Lundberg JON; Weitzberg E
Article: SHOCK. 1999;11(2):127-135
Angiotensin II receptor antagonism increases gut oxygen delivery but fails to improve intestinal mucosal acidosis in porcine endotoxin shock
Oldner A; Wanecek M; Weitzberg E; Rundgren M; Alving K; Ullman J; Rudehill A
Article: EUROPEAN RESPIRATORY JOURNAL. 1999;13(1):145-151
Endothelin_A-receptor antagonism attenuates pulmonary hypertension in porcine endotoxin shock
Wanecek M; Oldner A; Rudehill A; Sollevi A; Alving K; Weitzberg E
Article: ACTA PHYSIOLOGICA. 1998;163(3):235-239
Decreased pulmonary vascular resistance during nasal breathing: modulation by endogenous nitric oxide from the paranasal sinuses
Settergren G; Angdin M; Astudillo R; Gelinder S; Liska J; Lundberg JON; Weitzberg E
Article: GUT. 1998;42(5):696-702
The endothelin receptor antagonist bosentan restores gut oxygen delivery and reverses intestinal mucosal acidosis in porcine endotoxin shock
Oldner A; Wanecek M; Goiny M; Weitzberg E; Rudehill A; Alving K; Sollevi A
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 1998;33(2):164-169
Increased luminal nitric oxide in inflammatory bowel disease as shown with a novel minimally invasive method
Herulf M; Ljung T; Hellström PM; Weitzberg E; Lundberg JON
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1997;27(10):869-871
Increased nitric oxide production in collagenous and lymphocytic colitis
Lundberg JON; Herulf M; Olesen M; Bohr J; Tysk C; Wiklund NP; Morcos E; Hellstrom PM; Weitzberg E; Jarnerot G
Article: UROLOGY. 1997;50(2):189-191
Urinary nitrite: More than a marker of infection
Lundberg JON; Carlsson S; Engstrand L; Morcos E; Wiklund NP; Weitzberg E
Article: CRITICAL CARE MEDICINE. 1997;25(5):848-857
The endothelin receptor antagonist, bosentan, in combination with the cyclooxygenase inhibitor, diclofenac, counteracts pulmonary hypertension in porcine endotoxin shock
Wanecek M; Rudehill A; Hemsen A; Lundberg JM; Weitzberg E
Article: SHOCK. 1997;7(5):364-370
Cardiopulmonary dysfunction during porcine endotoxin shock is effectively counteracted by the endothelin receptor antagonist bosentan
Wanecek M; Oldner A; Rudehill A; Sollevi A; Alving K; Weitzberg E
Article: ACTA PHYSIOLOGICA. 1997;159(1):51-57
Heavy physical exercise decreases nitric oxide levels in the nasal airways in humans
Lundberg JON; Rinder J; Weitzberg E; Alving K; Lundberg JM
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;318(2-3):369-376
Effects of Ro 47-0203 and PD155080 on the plasma kinetics, receptor binding and vascular effects of endothelin in the pig
Hemsen A; Modin A; Wanecek M; Malmstrom RE; Weitzberg E
Article: ACTA PHYSIOLOGICA. 1996;158(4):343-347
Inhalation of nasally derived nitric oxide modulates pulmonary function in humans
Lundberg JON; Settergren G; Gelinder S; Lundberg JM; Alving K; Weitzberg E
Article: UROLOGY. 1996;48(5):700-702
Elevated nitric oxide in the urinary bladder in infectious and noninfectious cystitis
Lundberg JON; Ehren I; Jansson O; Adolfsson J; Lundberg JM; Weitzberg E; Alving K; Wiklund NP
Article: ARCHIVES OF DISEASE IN CHILDHOOD. 1996;75(4):323-326
Exhaled nitric oxide in paediatric asthma and cystic fibrosis
Lundberg JON; Nordvall SL; Weitzberg E; Kollberg H; Alving K
Article: CRITICAL CARE MEDICINE. 1996;24(9):1530-1536
Increased concentrations of endothelin-1 messenger RNA in tissues and endothelin-1 peptide in plasma in septic pigs: Modulation by betamethasone
Hemsen A; Modin A; Weitzberg E
Article: EUROPEAN RESPIRATORY JOURNAL. 1996;9(7):1344-1347
Calcium-independent and steroid-resistant nitric oxide synthase activity in human paranasal sinus mucosa
Lundberg JON; Weitzberg E; Rinder J; Rudehill A; Jansson O; Wiklund NP; Lundberg JM; Alving K
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1996;118(3):617-626
Bosentan-improved cardiopulmonary vascular performance and increased plasma levels of endothelin-1 in porcine endotoxin shock
Weitzberg E; Hemsen A; Rudehill A; Modin A; Wanecek M; Lundberg JM
Article: ACTA PHYSIOLOGICA. 1995;155(4):467-468
Nitric oxide, produced in the upper airways, may act in an 'aerocrine' fashion to enhance pulmonary oxygen uptake in humans
Lundberg JON; Lundberg JM; Settergren G; Alving K; Weitzberg E
Article: JOURNAL OF APPLIED PHYSIOLOGY. 1995;79(4):1255-1259
ET-3 IS EXTRACTED BY AND INDUCES POTENT VASOCONSTRICTION IN HUMAN SPLANCHNIC AND RENAL VASCULATURES
WEITZBERG E; HEMSEN A; LUNDBERG JM; AHLBORG G
Article: JOURNAL OF APPLIED PHYSIOLOGY. 1995;79(1):141-145
CIRCULATING ENDOTHELIN-1 REDUCES SPLANCHNIC AND RENAL BLOOD-FLOW AND SPLANCHNIC GLUCOSE-PRODUCTION IN HUMANS
AHLBORG G; WEITZBERG E; LUNDBERG JM
Article: JOURNAL OF APPLIED PHYSIOLOGY. 1995;78(6):2294-2300
METABOLIC AND VASCULAR EFFECTS OF CIRCULATING ENDOTHELIN-1 DURING MODERATELY HEAVY PROLONGED EXERCISE
AHLBORG G; WEITZBERG E; LUNDBERG J
Article: CRITICAL CARE MEDICINE. 1995;23(5):909-918
EFFECT OF COMBINED NITRIC-OXIDE INHALATION AND N-G-NITRO-L-ARGININE INFUSION IN PORCINE ENDOTOXIN-SHOCK
WEITZBERG E; RUDEHILL A; MODIN A; LUNDBERG JM
Article: NATURE MEDICINE. 1995;1(4):370-373
HIGH NITRIC-OXIDE PRODUCTION IN HUMAN PARANASAL SINUSES
LUNDBERG JON; FARKASSZALLASI T; WEITZBERG E; RINDER J; LIDHOLM J; ANGGARD A; HOKFELT T; LUNDBERG JM; ALVING K
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 1995;39(1):50-59
INHIBITORY EFFECTS OF DICLOFENAC ON THE ENDOTOXIN-SHOCK RESPONSE IN RELATION TO ENDOTHELIN TURNOVER IN THE PIG
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Review: NATURE REVIEWS DRUG DISCOVERY. 2015;14(9):623-641
Strategies to increase nitric oxide signalling in cardiovascular disease
Lundberg JO; Gladwin MT; Weitzberg E
Review: ORAL DISEASES. 2015;21(1):7-16
The oral microbiome and nitric oxide homoeostasis
Hezel MP; Weitzberg E
Review: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2014;38:45-57
Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health
Kapil V; Weitzberg E; Lundberg JO; Ahluwalia A
Review: ANNUAL REVIEW OF NUTRITION. 2013;33:129-159
Novel Aspects of Dietary Nitrate and Human Health
Weitzberg E; Lundberg JO
Review: FREE RADICAL BIOLOGY AND MEDICINE. 2012;53(10):1919-1928
Regulation of mitochondrial function and energetics by reactive nitrogen oxides
Larsen FJ; Schiffer TA; Weitzberg E; Lundberg JO
Editorial comment: JOURNAL OF PHYSIOLOGY-LONDON. 2011;589(22):5333-5334
Dietary nitrate - a slow train coming
Weitzberg E; Lundberg JO
Letter: JOURNAL OF APPLIED PHYSIOLOGY. 2011;111(2):616-617
Supplementation with nitrate and nitrite salts in exercise: a word of caution
Lundberg JO; Larsen FJ; Weitzberg E
Meeting abstract: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2011;24:S39-S40
Inorganic nitrite attenuates angiotensin ii induced contraction of renal microcirculation via xanthine oxidase-dependent no production
Carlstrom M; Gao X; Patzak A; Sendeski M; Weitzberg E; Lundberg J; Persson AEG
Meeting abstract: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2011;24:S30
Dietary inorganic nitrate mobilizes circulating angiogenic cells and reverses endothelial dysfunction
Heiss C; Meyer C; Heinen Y; Totzeck M; Luedike P; Kehmeier E; Ayoub N; Lundberg JO; Weitzberg E; Hendgen-Cotta U; Kelm M; Rassaf T
Meeting abstract: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2011;24:S27-S28
Dietary nitrate and glucose tolerance in young endothelial nitric oxide synthase null mice
Hezel M; Stensdotter M; Lundberg J; Weitzberg E
Review: CARDIOVASCULAR RESEARCH. 2011;89(3):525-532
Roles of dietary inorganic nitrate in cardiovascular health and disease
Lundberg JO; Carlstrom M; Larsen FJ; Weitzberg E
Review: ANESTHESIOLOGY. 2010;113(6):1460-1475
Nitrate-Nitrite-Nitric Oxide Pathway Implications for Anesthesiology and Intensive Care
Weitzberg E; Hezel M; Lundberg JO
Other: ANESTHESIOLOGY. 2010;113(6):1437-1438
Torsten Gordh (1907-2010) In Memoriam
Eriksson LI; Frostell C; Irestedt L; Lindahl S; Weitzberg E
Editorial comment: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2010;22(2):61-63
The biological role of nitrate and nitrite: The times they are a-changin' Preface
Lundberg JO; Weitzberg E
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49:S215
Mitochondrial Oxygen Affinity Predicts Basal Metabolic Rate in Humans
Schiffer TA; Larsen FJ; Ekblom B; Weitzberg E; Lundberg JO
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49:S116
Improved Mitochondrial Efficiency in Humans by Dietary Nitrate
Larsen FJ; Schiffer TA; Sahlin K; Ekblom B; Lundberg JO; Weitzberg E
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49:S36
Therapeutical Role of Dietary Inorganic Nitrate in eNOS-deficient mice with Metabolic Syndrome
Carlstrom M; Larsen FJ; Nystrom T; Hezel M; Borniquel S; Weitzberg E; Lundberg JO
Meeting abstract: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49:S16
Dietary Inorganic Nitrate Attenuates Oxidative Stress and Hypertension, and Prevents Cardiorenal injury in a Model of Renal and Cardiovascular Disease
Carlstrom M; Persson EG; Larsson E; Hezel M; Scheffer P; Teerlink T; Weitzberg E; Lundberg JO
Review: MEDICINAL RESEARCH REVIEWS. 2009;29(5):683-741
Nitrite as Regulator of Hypoxic Signaling in Mammalian Physiology
van Faassen EE; Babrami S; Feelisch M; Hogg N; Kelm M; Kim-Shapiro DB; Kozlov AV; Li H; Lundberg JO; Mason R; Nohl H; Rassaf T; Samouilov A; Slama-Schwok A; Shiva S; Vanin AF; Weitzberg E; Zweier J; Gladwin MT
Letter: CANCER RESEARCH. 2009;69(2):718
Comment re: Nitrite Activates Estrogen Receptor-α
Weitzberg E; Larsen F; Lundberg JO
Editorial comment: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2008;295(2):H477-H478
Nitrite reduction to nitric oxide in the vasculature
Lundberg JO; Weitzberg E
Letter: NATURE REVIEWS DRUG DISCOVERY. 2008;7(8):710
Downsides to the nitrate-nitrite-nitric oxide pathway in physiology and therapeutics? Reply from Lundberg, Weitzberg and Gladwin
Lundberg JO; Weitzberg E; Gladwin MT
Review: NATURE REVIEWS DRUG DISCOVERY. 2008;7(2):156-167
The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics
Lundberg JO; Weitzberg E; Gladwin MT
Letter: CRITICAL CARE. 2008;12(1):406
Extrapulmonary effects of nitric oxide inhalation therapy: time to consider new dosing regimes?
Lundberg JO; Weitzberg E
Other: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2007;51(9):1136-1137
Torsten Gordh celebrates his 100th anniversary
Lindahl SGE; Eriksson LI; Frostell C; Irestedt L; Weitzberg E
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2007;356(15):1590
Effects of dietary nitrate on blood pressure - Reply
Lundberg JO; Weitzberg E
Letter: NEW ENGLAND JOURNAL OF MEDICINE. 2006;355(26):2792-2793
Effects of dietary nitrate on blood pressure in healthy volunteers
Larsen FJ; Ekblom B; Sahlin K; Lundberg JO; Weitzberg E
Published conference paper: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA. 2006;119(5):2611-2617
Paranasal sinus ventilation by humming
Granqvist S; Sundberg J; Lundberg JO; Weitzberg E
Letter: CIRCULATION. 2005;112(6):e84
Letter regarding the article by Katz et al, "Vascular endothelial dysfunction and mortality risk in patients with chronic heart failure"
Lundberg J; Weitzberg E
Review: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(5):915-922
NO generation from nitrite and its role in vascular control
Lundberg JO; Weitzberg E
Editorial comment: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2005;49(4):434-436
L-arginine transport and sepsis
Weitzberg E
Review: NATURE CLINICAL PRACTICE GASTROENTEROLOGY AND HEPATOLOGY. 2005;2(2):96-102
Technology insight:: Calprotectin, lactoferrin and nitric oxide as novel markers of inflammatory bowel disease
Lundberg J; Hellström PM; Fagerhol MK; Weitzberg E; Roseth AG
Review: NATURE REVIEWS MICROBIOLOGY. 2004;2(7):593-602
Opinion - Nitrate, bacteria and human health
Lundberg JO; Weitzberg E; Cole JA; Benjamin N
Meeting abstract: SHOCK. 2004;21:114
Treatment with endothelin receptor antagonist Tezosentan and/or rescueflow (hypertonic saline/dextran) of LPS-induced endotoxin shock in anaesthetized pigs
Somell A; Suneson A; Weitzberg E; Sollevi A; Hjelmqvist H
Editorial comment: JOURNAL OF HYPERTENSION. 2004;22(1):27-29
Endothelin and nitric oxide in inflammation:: could there be a need for endothelin blocking anti-inflammatory drugs?
Malmström RE; Weitzberg E
Letter: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2003;289(3):302-303
Humming, nitric oxide, and paranasal sinus obstruction
Lundberg JO; Maniscalo M; Sofia M; Lundblad L; Weitzberg E
Review: EUROPEAN JOURNAL OF PHARMACOLOGY. 2000;407(1-2):1-15
The endothelin system in septic and endotoxin shock
Wanecek M; Weitzberg E; Rudehill A; Oldner A
Meeting abstract: GASTROENTEROLOGY. 2000;118(4):A364
Increased rectal nitric oxide in celiac disease following local gluten challenge.
Herulf M; Blomquist L; Ljung T; Weitzberg E; Lundberg J
Meeting abstract: GASTROENTEROLOGY. 2000;118(4):A104
Rectal nitric oxide pattern during treatment of active inflammatory bowel disease.
Ljung T; Herulf M; Weitzberg E; Lundberg J; Hellstrom PM
Review: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 1999;160(6):2104-2117
Recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide in adults and children - 1999
Slutsky AS; Drazen JM; Silkoff PE; Gaston BM; Holden W; Romero FA; Alving K; Baraldi E; Barnes PJ; Bratton D; Chatkin JM; Cremona G; de Gouw HWFM; Deykin A; Djupesland P; Douglas J; Erzurum S; Gustafsson LE; Haight J; Hogman M; Irvin C; Joerres R; Kissoon N; Lanz MJ; Lundberg JON; Massaro AE; Mehta S; Olin A; Permutt S; Qian W; Robbins R; Rubinstein I; Sylvester JT; Townley R; Weitzberg E; Zamel N
Meeting abstract: CRITICAL CARE MEDICINE. 1999;27(1):A131
Angiotensin II receptor antagonism increases gut oxygen delivery but fails to improve intestinal mucosal acidosis in porcine endotoxin shock.
Oldner A; Wanecek M; Weitzberg E; Rundgren M; Alving K; Ullman J; Rudehill A
Meeting abstract: GASTROENTEROLOGY. 1998;114(4):A994
Rectal measurements of nitric oxide in inflammatory bowel disease.
Herulf M; Ljung T; Hellström PM; Weitzberg E; Lundberg JON
Review: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 1998;2(1):1-7
Nonenzymatic nitric oxide production in humans
Weitzberg E; Lundberg JON
Review: NATURE MEDICINE. 1997;3(1):30-31
Nitric oxide and inflammation: The answer is blowing in the wind
Lundberg JON; Lundberg JM; Alving K; Weitzberg E
Review: EUROPEAN RESPIRATORY JOURNAL. 1996;9(12):2671-2680
Nitric oxide in exhaled air
Lundberg JON; Weitzberg E; Lundberg JM; Alving K
Review: LAKARTIDNINGEN. 1996;93(20):1945-1948
[Belching, flatus, breath. Measurements of airborne nitric oxide in the non-invasive diagnosis of inflammation].
Lundberg J; Lundberg JM; Alving K; Weitzberg E
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Professor, Senior, Department of Physiology and Pharmacology, Karolinska Institutet, 2025-2025
Professor, Department of Physiology and Pharmacology, Karolinska Institutet, 2024-2024
Professor/Senior Physician, Department of Physiology and Pharmacology, Karolinska Institutet, 2005-2024

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