Ebba Sohlberg

About me
Publications
Grants
CV
Public outreach and news

About me

Dedicated PhD with long-standing interest and experience in life sciences. My
current work is focused on cell therapy against cancer, specifically natural
killer (NK) cell based approaches. I have a strong interest in adaptive NK
cells in particular. Specialties include project management, regulatory work,
cell-based in vitro systems assessing the functional capacity of human immune
cells, flow cytometry and subsequent multiparameter analysis and
visualization.

Selected publications

Article: MED. 2024;:S2666-6340(24)00377-5
Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor.
Sætersmoen M; Kotchetkov IS; Torralba-Raga L; Mansilla-Soto J; Sohlberg E; Krokeide SZ; Hammer Q; Sadelain M; Malmberg K-J
Article: NATURE IMMUNOLOGY. 2024;25(8):1445-1459
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Netskar H; Pfefferle A; Goodridge JP; Sohlberg E; Dufva O; Teichmann SA; Brownlie D; Michaelsson J; Marquardt N; Clancy T; Horowitz A; Malmberg K-J
Article: BLOOD ADVANCES. 2023;7(16):4492-4504
Allelic variation of KIR and HLA tunes the cytolytic payload and determines functional hierarchy of NK cell repertoires
Philippon C; Tao S; Clement D; Haroun-Izquierdo A; Kichula KM; Netskar H; Brandt L; Oei VS; Kanaya M; Lanuza PM; Schaffer M; Goodridge JP; Horowitz A; Zhu F; Hammer Q; Sohlberg E; Majhi RK; Kveberg L; Onfelt B; Norman PJ; Malmberg K-J
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(11):e005577
Adaptive single-KIR⁺NKG2C⁺ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia
Haroun-Izquierdo A; Vincenti M; Netskar H; van Ooijen H; Zhang B; Bendzick L; Kanaya M; Momayyezi P; Li S; Wiiger MT; Hoel HJ; Krokeide SZ; Kremer V; Tjonnfjord G; Berggren S; Wikstroem K; Blomberg P; Alici E; Felices M; oenfelt B; Hoeglund P; Valamehr B; Ljunggren H-G; Bjoerklund A; Hammer Q; Kveberg L; Cichocki F; Miller JS; Malmberg K-J; Sohlberg E
Article: BLOOD. 2022;139(5):704-716
Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
Sohlberg E; Pfefferle A; Ask EH; Tschan-Plessl A; Jacobs B; Netskar H; Lorenz S; Kanaya M; Kosugi-Kanaya M; Meinke S; Mortberg A; Hoglund P; Sundin M; Carlsson G; Palmblad J; Malmberg K-J
Review: FRONTIERS IN IMMUNOLOGY. 2020;11:812
Deciphering Natural Killer Cell Homeostasis
Pfefferle A; Jacobs B; Haroun-Izquierdo A; Kveberg L; Sohlberg E; Malmberg K-J
Article: CELL REPORTS. 2019;29(8):2284-2294.e4
Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
Pfefferle A; Jacobs B; Netskar H; Ask EH; Lorenz S; Clancy T; Goodridge JP; Sohlberg E; Malmberg K-J
Article: CLINICAL CANCER RESEARCH. 2018;24(8):1834-1844
Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
Bjorklund AT; Carlsten M; Sohlberg E; Liu LL; Clancy T; Karimi M; Cooley S; Miller JS; Klimkowska M; Schaffer M; Watz E; Wikstrom K; Blomberg P; Wahlin BE; Palma M; Hansson L; Ljungman P; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
Review: IMMUNOGENETICS. 2017;69(8-9):547-556
Immune selection during tumor checkpoint inhibition therapy paves way for NK-cell "missing self" recognition
Malmberg K-J; Sohlberg E; Goodridge JP; Ljunggren H-G
Article: CELL REPORTS. 2016;15(5):1088-1099
Critical Role of CD2 Co-stimulation in Adaptive Natural Killer Cell Responses Revealed in NKG2C-Deficient Humans
Liu LL; Landskron J; Ask EH; Enqvist M; Sohlberg E; Traherne JA; Hammer Q; Goodridge JP; Larsson S; Jayaraman J; Oei VYS; Schaffer M; Tasken K; Ljunggren H-G; Romagnani C; Trowsdale J; Malmberg K-J; Beziat V
Article: BLOOD. 2013;121(14):2678-2688
NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs
Beziat V; Liu LL; Malmberg J-A; Ivarsson MA; Sohlberg E; Bjorklund AT; Retiere C; Sverremark-Ekstrom E; Traherne J; Ljungman P; Schaffer M; Price DA; Trowsdale J; Michaelsson J; Ljunggren H-G; Malmberg K-J

Articles

Article: ACTA BIOMATERIALIA. 2024;:S1742-7061(24)00664-0
Interleukin-12 decorated nanosized semiflexible Immunofilaments enable directed targeting and augmented IFNγ responses of natural killer cells.
Weiss L; Schluck M; Classens R; de Jonge PKJD; van der Waart A; Nguyen KG; Nguyen TT; Zaharoff DA; Malmberg K-J; Dolstra H; Figdor CG; Sohlberg E; Hammink R
Article: GENES AND IMMUNITY. 2024;:1-5
The HLA-B-21 M/T dimorphism associates with disease severity in COVID-19
Strunz B; Momayyezi P; Bilev E; Muvva JR; Chen P; Bister J; Schaffer M; Akber M; Cornillet M; Horowitz A; Malmberg K-J; Rooyackers O; Aleman S; Ljunggren H-G; Bjorkstrom NK; Stralin K; Hammer Q; Berglin L; Bergsten H; Brighenti S; Brownlie D; Buggert M; Butrym M; Chambers BJ; Cuapio A; Lozano ID; Dillner L; Djarv T; Dzidic M; Emgard J; Eriksson LI; Flodstrom-Tullberg M; Glans H; Gorin J-B; Grip J; Haroun-Izquierdo A; Henriksson E; Hertwig L; Kalsum S; Kammann T; Klingstroem J; Kokkinou E; Kvedaraite E; Loreti MG; Lourda M; Maleki KT; Marquardt N; Martensson J; Maucourant C; Michaelsson J; Mjosberg J; Moll K; Naucler P; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Persson BP; Radler L; Religa D; Ringqvist E; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Sohlberg E; Soini T; Soennerborg A; Svensson M; Tynell J; Unge C; Varnaite R; von Kries A; Wullimann D
Article: JOURNAL OF INFECTIOUS DISEASES. 2024;230(2):e318-e326
Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19
Strunz B; Maucourant C; Mehta A; Wan H; Du L; Sun D; Chen P; Nordlander A; Gao Y; Cornillet M; Bister J; Kvedaraite E; Christ W; Klingstrom J; Geanon D; Parke A; Ekwall-Larson A; Rivino L; MacAry PA; Aleman S; Buggert M; Ljunggren H-G; Pan-Hammarstrom Q; Lund-Johansen F; Stralin K; Bjorkstrom NK
Article: BLOOD ADVANCES. 2024;8(3):571-580
Clinical and immunological features in ACKR1/DARC-associated neutropenia
Palmblad J; Sohlberg E; Nilsson CC; Lindqvist H; Deneberg S; Ratcliffe P; Meinke S; Mortberg A; Klimkowska M; Hoglund P
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2023;29(6):376.e1-376.e11
Effect of mTOR Inhibition with Sirolimus on Natural Killer Cell Reconstitution in Allogeneic Stem Cell Transplantation
Haroun-Izquierdo A; Lanuza PM; Pfefferle A; Netskar H; Ask EH; Torlen J; Bjorklund A; Sohlberg E; Malmberg K-J
Journal article: JOURNAL OF IMMUNOLOGY. 2023;210(1_Supplement):75.20
Pre-existing SARS-CoV-2-reactive CD4 +T cells are established and highly functional in early childhood
Olofsson A; Humbert M; Niessl J; Hodcroft E; Gao Y; Sohlberg E; Malmberg K-J; Lund-Johansen F; Björkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(12):e2220320120
Functional SARS-CoV-2 cross-reactive CD4⁺ T cells established in early childhood decline with age
Humbert M; Olofsson A; Wullimann D; Niessl J; Hodcroft EB; Cai C; Gao Y; Sohlberg E; Dyrdak R; Mikaeloff F; Neogi U; Albert J; Malmberg K-J; Lund-Johansen F; Aleman S; Bjorkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
The Karolinska KI/K COVID-19 immune atlas: An open resource for immunological research and educational purposes
Ljunggren H-G; Heggernes Ask E; Cornillet Jeannin M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio Gomez A; Dzidic M; Filipovic I; Flodstrom-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Eriksson LI; Aleman S; Malmberg K-J; Stralin K; Bjorkstrom NK
Article: CELL REPORTS. 2022;38(10):110503
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer Q; Dunst J; Christ W; Picarazzi F; Wendorff M; Momayyezi P; Huhn O; Netskar HK; Maleki KT; Garcia M; Sekine T; Sohlberg E; Azzimato V; Aouadi M; Degenhardt F; Franke A; Spallotta F; Mori M; Michaelsson J; Bjorkstrom NK; Rueckert T; Romagnani C; Horowitz A; Klingstrom J; Ljunggren H-G; Malmberg K-J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
MAIT cell activation and dynamics associated with COVID-19 disease severity
Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgard J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Bjorkstrom NK; Aleman S; Buggert M; Klingstrom J; Stralin K; Sandberg JK
Article: SCIENCE IMMUNOLOGY. 2020;5(50):eabd6832
Natural killer cell immunotypes related to COVID-19 disease severity
Maucourant C; Filipovic I; Ponzetta A; Aleman S; Cornillet M; Hertwig L; Strunz B; Lentini A; Reinius B; Brownlie D; Cuapio A; Ask EH; Hull RM; Haroun-Izquierdo A; Schaffer M; Klingstrom J; Folkesson E; Buggert M; Sandberg JK; Eriksson LI; Rooyackers O; Ljunggren H-G; Malmberg K-J; Michaelsson J; Marquardt N; Hammer Q; Stralin K; Bjorkstrom NK
Article: ONCOTARGET. 2015;6(33):34178-34190
Imprint of 5-azacytidine on the natural killer cell repertoire during systemic treatment for high-risk myelodysplastic syndrome
Sohlberg E; Pfefferle A; Andersson S; Baumann BC; Hellstrom-Lindberg E; Malmberg K-J
Article: JOURNAL OF IMMUNOLOGY. 2015;195(7):3374-3381
Microchip-Based Single-Cell Imaging Reveals That CD56^dim CD57^-KIR^-NKG2A⁺ NK Cells Have More Dynamic Migration Associated with Increased Target Cell Conjugation and Probability of Killing Compared to CD56^dimCD57^-KIR^-NKG2A^- NK Cells
Forslund E; Sohlberg E; Enqvist M; Olofsson PE; Malmberg K-J; Onfelt B
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2014;71(2):178-188
Pre-Eclampsia Affects Cord Blood NK Cell Expression of Activation Receptors and Serum Cytokine Levels but Not CB Monocyte Characteristics
Sohlberg E; Saghafian-Hedengren S; Bachmayer N; Hamad RR; Bremme K; Holmlund U
Journal article: BIO-PROTOCOL. 2014;4(14)
In vitro EBV Infection of Mononuclear Cells that Have Been Cryo-preserved
Saghafian-Hedengren S; Sohlberg E; Theorell J; Carvalho-Queiroz C; Nagy N; Persson J-O; Nilsson C; Bryceson Y; Sverremark-Ekström E
Article: JOURNAL OF VIROLOGY. 2013;87(24):13446-13455
Epstein-Barr Virus Coinfection in Children Boosts Cytomegalovirus-Induced Differentiation of Natural Killer Cells
Saghafian-Hedengren S; Sohlberg E; Theorell J; Carvalho-Queiroz C; Nagy N; Persson J-O; Nilsson C; Bryceson YT; Sverremark-Ekstrom E
Article: JOURNAL OF IMMUNOLOGY. 2013;191(11):5669-5676
Cytomegalovirus-Seropositive Children Show Inhibition of In Vitro EBV Infection That Is Associated with CD8⁺CD57⁺ T Cell Enrichment and IFN-γ
Sohlberg E; Saghafian-Hedengren S; Rasul E; Marchini G; Nilsson C; Klein E; Nagy N; Sverremark-Ekstrom E
Article: JOURNAL OF IMMUNOLOGICAL METHODS. 2012;385(1-2):60-70
Simultaneous detection of the two main proliferation driving EBV encoded proteins, EBNA-2 and LMP-1 in single B cells
Rasul AE; Nagy N; Sohlberg E; Adori M; Claesson H-E; Klein G; Klein E
Article: IMMUNOLOGY. 2011;133(1):41-50
Cord blood monocyte subsets are similar to adult and show potent peptidoglycan-stimulated cytokine responses
Sohlberg E; Saghafian-Hedengren S; Bremme K; Sverremark-Ekstrom E
Journal article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2009;62(5):348
Women with Pre-Eclampsia have an Altered NKG2A and NKG2C Receptor Expression on Peripheral Blood Natural Killer Cells (vol 62, pg 147, 2009)
Bachmayer N; Sohlberg E; Sundstrom Y; Hamad RR; Berg L; Bremme K; Sverremark-Ekstrom E
Article: AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY. 2009;62(3):147-157
Women with Pre-Eclampsia Have an Altered NKG2A and NKG2C Receptor Expression on Peripheral Blood Natural Killer Cells
Bachmayer N; Sohlberg E; Sundstrom Y; Hamad RR; Berg L; Bremme K; Sverremark-Ekstrom E
Article: JOURNAL OF IMMUNOLOGY. 2009;182(4):2511-2517
Herpesvirus Seropositivity in Childhood Associates with Decreased Monocyte-Induced NK Cell IFN-γ Production
Saghafian-Hedengren S; Sundstrom Y; Sohlberg E; Nilsson C; Linde A; Troye-Blomberg M; Berg L; Sverremark-Ekstrom E
Show more

All other publications

Conference publication: 2024;:a1268
1146 CAR engineering of adaptive NK cells to guide missing-self responses against B cell malignancies
Torralba-Raga L; Melchers K; Martin KE; Wiiger M; Zandstra-Krokeide S; Sohlberg E; Malmberg K-J
Conference publication: 2024;:a438
382 Generation of immune-evasive allogeneic adaptive NK cell therapies
Martin KE; Torralba-Raga L; Melchers K; Zandstra-Krokeide S; Wiiger MT; Sohlberg E; Malmberg K-J
Preprint: BIORXIV. 2024;BIORXIV
A genetically engineered therapeutic lectin inhibits human influenza A virus infection and sustains robust virus-specific CD8 T cell expansion.
Yu M; Lin A; Baharom F; Li S; Legendre M; Covés-Datson E; Sohlberg E; Schlisio S; Loré K; Markovitz DM; Smed-Sörensen A
Preprint: BIORXIV. 2023
Targeting HLA-E Positive Cancers with a Novel NKG2A/C Switch Receptor
Sætersmoen M; Kotchetkov I; Torralba-Raga L; Mansilla-Soto J; Sohlberg E; Krokeide SZ; Hammer Q; Sadelain M; Malmberg K-J
Preprint: BIORXIV. 2023
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Netskar H; Pfefferle A; Goodridge J; Sohlberg E; Dufva O; Teichmann S; Clancy T; Horowitz A; Malmberg K-J
Conference publication: JOURNAL OF IMMUNOLOGY. 2023;210(1)
Pre-existing SARS-CoV-2-reactive CD4⁺ T cells are established and highly functional in early childhood
Olofsson A; Humbert M; Niessl J; Hodcroft E; Gao Y; Sohlberg E; Malmberg K-J; Lund-Johansen F; Bjorkhem-Bergman L; Jenmalm MC; Ljunggren H-G; Buggert M; Karlsson AC
Conference publication: BLOOD. 2020;136:24-25
Systems-Level Analysis of the Immune Repertoire in Neutropenia Reveal Arrested NK Cell Differentiation and Exhaustion
Sohlberg E; Pfefferle A; Ask EH; Tschan-Plessl A; Jacobs B; Lorenz S; Meinke S; Hoglund P; Sundin M; Karlsson G; Palmblad J; Malmberg K-J
Preprint: BIORXIV. 2019
A Temporal Transcriptional Map of Human Natural Killer Cell Differentiation
Pfefferle A; Netskar H; Ask EH; Lorenz S; Goodridge JP; Sohlberg E; Clancy T; Malmberg K-J
Preprint: BIORXIV. 2019
Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
Pfefferle A; Jacobs B; Ask EH; Lorenz S; Clancy T; Goodridge JP; Sohlberg E; Malmberg K-J
Preprint: SSRN ELECTRONIC JOURNAL. 2019
Intra-Lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity
Pfefferle A; Jacobs B; Ask EH; Lorenz S; Clancy T; Goodridge JP; Sohlberg E; Malmberg K-J
Meeting abstract: BLOOD. 2018;132:195
Efficient Scale-up and Pre-Clinical Evaluation of NKG2C+Adaptive NK Cell Expansion for Therapy Against High-Risk AML/MDS
Sohlberg E; Haroun-Izquierdo A; Bjorklund AT; Cooley S; Wiiger MT; Goodridge P; Hoel HJ; Pfefferle A; Chrobook M; Kremer V; Hellstrom-Lindberg E; Ask EH; Pontus B; Valamehr B; Guldevall K; van Ooijen H; Onfelt B; Alici E; Ljunggren H-G; Miller JS; Malmberg K-J
Review: SEMINARS IN IMMUNOLOGY. 2017;31:20-29
Natural killer cell-mediated immunosurveillance of human cancer
Malmberg K-J; Carlsten M; Bjorklund A; Sohlberg E; Bryceson YT; Ljunggren H-G
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):266
Donor intrinsic metabolic set points determine proliferation in human NK cells
Pfefferle A; Jacobs B; Clancy T; Sohlberg E; Goodridge JP; Malmberg K-J
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):303
Profound NK cell differentiation block in a subgroup of neutropenic patients
Sohlberg E; Pfefferle A; Clancy T; Sundin M; Carlsson G; Palmblad J; Malmberg K-J
Conference publication: BLOOD. 2017;130
Complete Remission and Signs of Immunoediting Following Haploidentical NK Cell Therapy in Refractory High-Risk MDS and AML Ell Therapy in Refractory High-Risk MDS and AML
Bjorklund AT; Carlsten M; Sohlberg E; Clancy T; Liu L; Karimi M; Cooley S; Miller JS; Watz E; Wahlin BE; Palma M; Hansson L; Ljungman P; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
Conference publication: BONE MARROW TRANSPLANTATION. 2016;51:S97-S98
ADOPTIVELY TRANSFERRED HAPLOIDENTICAL NK CELLS AGAINST REFRACTORY MDS, HIGH-RISK MDS AND REFRACTORY AML AS A BRIDGE TO TRANSPLANTATION. COMPLETE REMISSION ASSOCIATED WITH DETECTABLE NK CELLS
Bjorklund AT; Carlsten M; Sohlberg E; Liu L; Schaffer M; Watz E; Ljungman P; Hellstrom-Lindberg E; Ljunggren H-G; Malmberg K-J
Meeting abstract: LEUKEMIA RESEARCH. 2015;39:S25-S26
ADOPTIVELY TRANSFERRED HAPLOIDENTICAL NK CELLS AGAINST REFRACTORY MDS, HIGH-RISK MDS AND REFRACTORY AML AS A BRIDGE TO TRANSPLANTATION. COMPLETE REMISSION ASSOCIATED WITH DETECTABLE NK CELLS
Bjorklund AT; Carlsten M; Liu L; Schaffer M; Watz E; Palma M; Hansson L; Mollgard L; Cooley SA; Miller JS; Ljungman PT; Hellstrom-Lindberg E; Ljunggren HG; Malmberg KJ
Conference publication: JOURNAL OF IMMUNOLOGY. 2013;190:183.15
NKG2C+CD57+CD56dim NK cells are enriched following Epstein-Barr virus transformed lymphoblastoid cell line co-culture with peripheral blood mononuclear cells from cytomegalovirus plus donors
Saghafian-Hedengren S; Sohlberg E; Theorell J; Queiroz-Carvalho C; Nagy N; Nilsson C; Bryceson Y; Sverremark-Ekstrom E
Conference publication: IMMUNOLOGY. 2012;137:128-129
Mapping the diversity of human KIR repertoires and their adaptation to infection
Beziat V; Liu L; Sohlberg E; Retiere C; Traherne JA; Sverremark-Ekstrom E; Trowsdale J; Michaelsson J; Ljunggren HG; Malmberg KJ
Conference publication: IMMUNOLOGY. 2011;135:97
Epstein-Barr virus latency and weaker NK-cell responses in children - exploring the immune modulating potential of EBV
Saghafian-Hedengren S; Sohlberg E; Nilsson C; Sverremark-Ekstrom E
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):231
Inverse association between herpesvirus seropositivity and activation of innate immunity in children
Saghafian-Hedengren S; Sundstrom Y; Sohlberg E; Nilsson C; Lilja G; Marita T-B; Louise B; Eva S-E
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2008;68(2):225-226
Pre-eclampsia does not influence the peripheral natural killer cell population with regard to their subpopulations and receptor expression
Bachmayer N; Sundstrom Y; Berg L; Sohlberg E; Hamad RR; Bremme K; Sverremark-Ekstrom E
Show more

Grants

Lysosomal Remodelling in Natural Killer Cells – New Targets for Immune-Gene Therapy
Swedish Research Council
1 January 2021 - 31 December 2024

Employments

Project Coordinator, Department of Medicine, Huddinge, Karolinska Institutet, 2018-

Supervisor

Alvaro Haroun-Izquierdo, NATURAL KILLER CELL DEVELOPMENT AND FUNCTION IN THE CONTEXT OF ALLOGENEIC STEM CELL TRANSPLANTATION AND CELL THERAPY
Aline Pfefferle, Dynamics of natural killer cell homeostasis : implications for cell-based cancer immunotherapy.

Committee work

Member, PhD half-time committee Kyra Kuhnigk, Department of Medicine, Karolinska Institutet, 2023-

Journal reviewing

Reviewer
Cancer Research, AACR Journals, Anonymous peer review, 2024
Reviewer
Clinical Cancer Research, AACR Journals, Anonymous peer review, 2021
Reviewer
Scientific Reports, Nature Portfolio, 2019
Reviewer
Plos One, PLOS, 2017

Conference/event participation

Invited speaker, NextGenNK and CCRM Nordic mini-symposium, Stockholm, Sweden, https://news.ki.se/calendar/nextgennk-and-ccrm-nordic-mini-symposium, ADAPT-NK - an off-the-shelf cell therapy to unleash NK cell potential, 2025
Invited speaker, 18th Tumor Immunology and Oncology Meeting, Brandenburg, Germany, Unleashing the untapped power of adaptive NK cell therapy in cancer treatment, 2024
Invited speaker, NK Cell & ILC meeting 2024, Lyon, France, 2024
Invited speaker, INNATE KILLER SUMMIT Europe 2023, London, UK, 2023
Invited speaker, European Hematology Association 2023 HYBRID CONGRESS, Frankfurt, Germany, Adaptive NK cells as therapy for leukemia, 2023
Invited speaker, ALLOGENEIC CELL THERAPY SUMMIT, Boston, US, ADAPT-NK An Off-the-Shelf Allogeneic NK Cell Therapy Using Select Superdonors, 2023
Invited speaker, ATMP SWEDEN, Stockholm, Sweden, 2022
Invited speaker, Young Researchers in Hematology, Stockholm, Sweden, 2022
Oral presenter of own accepted abstract, 62nd ASH Annual Meeting and Exposition, Virtual, 2020
Invited speaker, MILTENYI Cell and Gene Therapy day, Copenhagen, Denmark, 2019
Oral presenter of own accepted abstract, KIR WORKSHOP - Camogli, Italy, 2018
Oral presenter of own accepted abstract, SCANDINAVIAN SOCIETY FOR IMMUNOLOGY ANNUAL MEETING 2017- Stockholm, Sweden, 2017
Oral presenter of own accepted abstract, KIR WORKSHOP- Winchester, England, 2015
Oral presenter of own accepted abstract, THE 14th INTERNATIONAL CONGRESS OF IMMUNOLOGY: Kobe, Japan, , 2010

About me

Selected publications

Articles

All other publications

Grants

Employments

Supervisor

Committee work

Journal reviewing

Conference/event participation

News from KI

Events from KI