Dionysis Nikolopoulos

Publications
Public outreach and news

Articles

Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2024;:ard-2024-226051
Molecular basis for the disease-modifying effects of belimumab in systemic lupus erythematosus and molecular predictors of early response: blood transcriptome analysis implicates the innate immunity and DNA damage response pathways
Moysidou G-S; Garantziotis P; Sentis G; Nikoleri D; Malissovas N; Nikoloudaki M; Stergioti E-M; Polia S; Paschalidis N; Filia A; Grigoriou M; Nikolopoulos D; Kapsala N; Katechis S; Fanouriakis A; Bertsias G; Boumpas DT
Journal article: RHEUMATOLOGY. 2024;:keae575
Trajectories of disease evolution upon treatment initiation in systemic lupus erythematosus: results from four clinical trials of belimumab
Parodis I; Lindblom J; Tsoi A; Palazzo L; Sporre KB; Enman Y; Nikolopoulos D; Beretta L
Article: RHEUMATOLOGY INTERNATIONAL. 2024;44(9):1679-1689
Neuropsychiatric involvement in systemic lupus erythematosus contributes to organ damage beyond the nervous system: a post-hoc analysis of 5 phase III randomized clinical trials
Nikolopoulos D; Cetrez N; Lindblom J; Parodis I
Article: RHEUMATOLOGY. 2024;63(9):2494-2502
Patients with NPSLE experience poorer HRQoL and more fatigue than SLE patients with no neuropsychiatric involvement, irrespective of neuropsychiatric activity
Nikolopoulos D; Cetrez N; Lindblom J; Palazzo L; Enman Y; Parodis I
Article: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(9):1132-1143
Disentangling the riddle of systemic lupus erythematosus with antiphospholipid syndrome: blood transcriptome analysis reveals a less-pronounced IFN-signature and distinct molecular profiles in venous versus arterial events
Nikolopoulos D; Loukogiannaki C; Sentis G; Garantziotis P; Manolakou T; Kapsala N; Nikoloudaki M; Pieta A; Flouda S; Parodis I; Bertsias G; Fanouriakis A; Filia A; Boumpas DT
Article: KIDNEY INTERNATIONAL REPORTS. 2024;9(6):1817-1835
Interferon and B-cell Signatures Inform Precision Medicine in Lupus Nephritis
Parodis I; Lindblom J; Toro-Dominguez D; Beretta L; Borghi MO; Castillo J; Carnero-Montoro E; Enman Y; Mohan C; Alarcon-Riquelme ME; Barturen G; Nikolopoulos D; PRECISESADS Clinical Consortium OBOPREC
Journal article: RHEUMATOLOGY. 2024;:keae278
Can we predict kidney involvement in patients with systemic lupus erythematosus? A retrospective cohort study with independent validation
Katechis S; Nikolopoulos D; Flouda S; Adamichou C; Chavatza K; Kapsala N; Katsimbri P; Bertsias G; Boumpas DT; Fanouriakis A
Article: LUPUS. 2024;33(2):166-171
Impaired serotonin synthesis in hippocampus of murine lupus represents an early neuropsychiatric event
Nikolopoulos D; Nakos-Bimpos M; Manolakou T; Polissidis A; Boumpas DT
Article: BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY. 2023;37(4):101894
Reframing health disparities in SLE: A critical reassessment of racial and ethnic differences in lupus disease outcomes
Parodis I; Lanata C; Nikolopoulos D; Blazer A; Yazdany J
Article: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):646-657
Microglia activation in the presence of intact blood-brain barrier and disruption of hippocampal neurogenesis via IL-6 and IL-18 mediate early diffuse neuropsychiatric lupus
Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Bertsias G; Koutmani Y; Boumpas DT
Journal article: BMC GENOMICS. 2023;24(1):207
Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy
Nikolakis D; Garantziotis P; Sentis G; Fanouriakis A; Bertsias G; Frangou E; Nikolopoulos D; Banos A; Boumpas DT
Journal article: LUPUS. 2023;32(2):225-230
Relapses are common in severe hematologic systemic lupus erythematosus and may be prevented by early institution of immunosuppressive agents: Α real-life single-center study
Moysidou G-S; Garantziotis P; Nikolopoulos D; Katsimbri P; Fanouriakis A; Boumpas DT
Journal article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2023;41(1):74-81
From first symptoms to diagnosis of systemic lupus erythematosus: mapping the journey of patients in an observational study
Kapsala NN; Nikolopoulos DS; Flouda SP; Chavatza AP; Tseronis DD; Aggelakos MD; Katsimbri PP; Bertsias GK; Fanouriakis AC; Boumpas DT
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1203848
A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
Sentis G; Loukogiannaki C; Malissovas N; Nikolopoulos D; Manolakou T; Flouda S; Grigoriou M; Banos A; Boumpas DTT; Filia A
Article: SCIENCE ADVANCES. 2022;8(43):eabo5840
ATR-mediated DNA damage responses underlie aberrant B cell activity in systemic lupus erythematosus
Manolakou T; Nikolopoulos D; Gkikas D; Filia A; Samiotaki M; Stamatakis G; Fanouriakis A; Politis P; Banos A; Alissafi T; Verginis P; Boumpas DT
Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(10):1409-1419
Cross-species transcriptome analysis for early detection and specific therapeutic targeting of human lupus nephritis
Frangou E; Garantziotis P; Grigoriou M; Banos A; Nikolopoulos D; Pieta A; Doumas SA; Fanouriakis A; Hatzioannou A; Manolakou T; Alissafi T; Verginis P; Athanasiadis E; Dermitzakis E; Bertsias G; Filia A; Boumpas DT
Journal article: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. 2022;40(9):1769-1778
Remission or low disease activity at pregnancy onset are linked to improved foetal outcomes in women with systemic lupus erythematosus: results from a prospective observational study
Ntali S; Nikolopoulos D; Pantazi L; Emmanouilidou E; Papagoras C; Fanouriakis A; Dimopoulou D; Kallitsakis I; Boki K; Dania V; Sidiropoulos PI; Boumpas DT; Bertsias G
Journal article: RHEUMATOLOGY INTERNATIONAL. 2022;42(8):1307-1319
Tailored treatment strategies and future directions in systemic lupus erythematosus
Nikolopoulos D; Fotis L; Gioti O; Fanouriakis A
Journal article: AMERICAN JOURNAL OF MEDICINE. 2022;135(2):244-253.e3
First Diagnosis of Systemic Lupus Erythematosus in Hospitalized Patients: Clinical Phenotypes and Pitfalls for the Non-Specialist
Kapsala N; Nikolopoulos D; Flouda S; Chavatza A; Tseronis D; Aggelakos M; Katsimbri P; Bertsias G; Fanouriakis A; Boumpas DT
Journal article: FRONTIERS IN IMMUNOLOGY. 2022;13:1074044
Clinical response trajectories and drug persistence in systemic lupus erythematosus patients on belimumab treatment: A real-life, multicentre observational study
Nikoloudaki M; Nikolopoulos D; Koutsoviti S; Flouri I; Kapsala N; Repa A; Katsimbri P; Theotikos E; Pitsigavdaki S; Pateromichelaki K; Bertsias A; Elezoglou A; Sidiropoulos P; Fanouriakis A; Boumpas D; Bertsias G
Journal article: FRONTIERS IN NEUROLOGY. 2022;13:889613
Demyelinating Syndromes in Systemic Lupus Erythematosus: Data From the "Attikon" Lupus Cohort
Nikolopoulos D; Kitsos D; Papathanasiou M; Kapsala N; Garantziotis P; Pieta A; Gioti O; Grivas A; Voumvourakis K; Boumpas D; Fanouriakis A
Journal article: RHEUMATOLOGY. 2021;60(9):4166-4174
Demyelination with autoimmune features: a distinct clinical entity? Results from a longitudinal cohort
Nikolopoulos D; Kitsos D; Papathanasiou M; Chondrogianni M; Theodorou A; Garantziotis P; Pieta A; Doskas T; Bertsias G; Voumvourakis K; Boumpas DT; Fanouriakis A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(9):1175-1182
Quality indicators for systemic lupus erythematosus based on the 2019 EULAR recommendations: development and initial validation in a cohort of 220 patients
Chavatza K; Kostopoulou M; Nikolopoulos D; Gioti O; Togia K; Andreoli L; Aringer M; Boletis J; Doria A; Houssiau FA; Jayne D; Mosca M; Svenungsson E; Tincani A; Bertsias G; Fanouriakis A; Boumpas DT
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(6):758-766
Lupus or not? SLE Risk Probability Index (SLERPI): a simple, clinician-friendly machine learning-based model to assist the diagnosis of systemic lupus erythematosus
Adamichou C; Genitsaridi I; Nikolopoulos D; Nikoloudaki M; Repa A; Bortoluzzi A; Fanouriakis A; Sidiropoulos P; Boumpas DT; Bertsias GK
Journal article: EXPERT REVIEW OF CLINICAL IMMUNOLOGY. 2021;17(4):317-329
Treatment of neuropsychiatric systemic lupus erythematosus: clinical challenges and future perspectives
Nikolopoulos D; Fanouriakis A; Bertsias G
Journal article: CLINICAL RHEUMATOLOGY. 2021;40(4):1447-1456
The role of plasma exchange in antineutrophil cytoplasmic antibody-associated vasculitis: a meta-analysis
Bellos I; Michelakis I; Nikolopoulos D
Article: SEMINARS IN ARTHRITIS AND RHEUMATISM. 2020;50(6):1387-1393
Lymphopenia as a risk factor for neurologic involvement and organ damage accrual in patients with systemic lupus erythematosus: A multi-center observational study
Yavuz S; Cansu DU; Nikolopoulos D; Crisafulli F; Antunes AM; Adamichou C; Reid S; Stagnaro C; Andreoli L; Tincani A; Moraes-Fontes MF; Mosca M; Leonard D; Jonsen A; Bengtsson A; Svenungsson E; Gunnarsson I; Dahlqvist SR; Sjowall C; Bertsias G; Fanouriakis A; Ronnblom L
Journal article: MEDITERRANEAN JOURNAL OF RHEUMATOLOGY. 2020;31(3):330
Interstitial Pneumonia with Autoimmune Features (IPAF): A Single-Centre, Prospective Study.
Karampeli M; Thomas K; Flouda S; Chavatza A; Nikolopoulos D; Pieta A; Tseronis D; Aggelakos M; Kassara D; Tzavara V; Katsimbri P; Boumpas D; Karageorgas T
Journal article: MEDITERRANEAN JOURNAL OF RHEUMATOLOGY. 2020;31(3):366
Mitophagy Balance in Various Cell Subsets in Patients with ANCA-Associated Vasculitis and Correlation with the Presence of Anti-Neutrophil Cytoplasmic Antibodies.
Banos A; Thomas K; Garantziotis P; Malissovas N; Filia A; Pieta A; Nikolopoulos D; Moustafa S; Panagiotopoulos A; Boumpas DT; Vassilopoulos D
Journal article: LUPUS SCIENCE & MEDICINE. 2020;7(1):e000394
Transition to severe phenotype in systemic lupus erythematosus initially presenting with non-severe disease: implications for the management of early disease
Nikolopoulos DS; Kostopoulou M; Pieta A; Flouda S; Chavatza K; Banos A; Boletis J; Katsimbri P; Boumpas DT; Fanouriakis A
Journal article: LUPUS. 2020;29(5):514-522
Evolving phenotype of systemic lupus erythematosus in Caucasians: low incidence of lupus nephritis, high burden of neuropsychiatric disease and increased rates of late-onset lupus in the 'Attikon' cohort
Nikolopoulos D; Kostopoulou M; Pieta A; Karageorgas T; Tseronis D; Chavatza K; Flouda S; Rapsomaniki P; Banos A; Kremasmenou E; Tzavara V; Katsimbri P; Fanouriakis A; Boumpas DT
Article: MEDITERRANEAN JOURNAL OF RHEUMATOLOGY. 2020;31(1):87-91
Development and Implementation of a Pilot Registry for Monitoring the Efficacy and Safety of Novel Therapies in Patients with Systemic Lupus Erythematosus.
Adamichou C; Flouri I; Fanouriakis A; Nikoloudaki M; Nikolopoulos D; Repa A; Boki K; Chatzidionysiou K; Garyfallos A; Boumpas D; Sidiropoulos P; Bertsias G
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(2):232-241
In an early SLE cohort the ACR-1997, SLICC-2012 and EULAR/ACR-2019 criteria classify non-overlapping groups of patients: use of all three criteria ensures optimal capture for clinical studies while their modification earlier classification and treatment
Adamichou C; Nikolopoulos D; Genitsaridi I; Bortoluzzi A; Fanouriakis A; Papastefanakis E; Kalogiannaki E; Gergianaki I; Sidiropoulos P; Boumpas DT; Bertsias GK
Journal article: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(2):242-253
Transcriptome reprogramming and myeloid skewing in haematopoietic stem and progenitor cells in systemic lupus erythematosus
Grigoriou M; Banos A; Filia A; Pavlidis P; Giannouli S; Karali V; Nikolopoulos D; Pieta A; Bertsias G; Verginis P; Mitroulis I; Boumpas DT
Journal article: CURRENT OPINION IN RHEUMATOLOGY. 2019;31(6):669-677
Update on the pathogenesis of central nervous system lupus
Nikolopoulos D; Fanouriakis A; Boumpas DT
Journal article: BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY. 2019;33(4):101425
Suspected systemic rheumatic diseases in patients presenting with cytopenias
Nikolopoulos D; Adamichou C; Bertsias G
Journal article: MEDITERRANEAN JOURNAL OF RHEUMATOLOGY. 2019;30(1):7-15
Cerebrovascular Events in Systemic Lupus Erythematosus: Diagnosis and Management.
Nikolopoulos D; Fanouriakis A; Boumpas DT
Journal article: MEDITERRANEAN JOURNAL OF RHEUMATOLOGY. 2018;29(4):228-231
Birth Registry of Women With Systematic Lupus Erythematosus: The Greek Experience.
Ntali S; Pantazi L; Mpoki K; Nikolopoulos D; Fanouriakis A; Kallitsakis I; Papagoras C; Dimopoulou D; Kteniadaki E; Emmanouilidou E; Chania V; Bertsias G
Journal article: MEDITERRANEAN JOURNAL OF RHEUMATOLOGY. 2018;29(4):232-235
Comparative analysis of the sensitivity and specificity of the classification criteria and correlation with prognosis of disease in patients with Systemic Lupus Erythematosus.
Adamichou C; Nikolopoulos D; Papastefanakis E; Kalogiannaki E; Gergianaki I; Kountouri A; Repa A; Avgoustidis N; Kougkas N; Sidiropoulos P; Fanouriakis A; Bertsias G
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Review: EXPERT OPINION ON PHARMACOTHERAPY. 2024;25(6):705-716
Advances in the pharmacological management of systemic lupus erythematosus
Tsoi A; Nikolopoulos D; Parodis I
Conference publication: 2024;:a14-a15
O11 Unsupervised machine-learning identifies distinct clusters based on B cell phenotyping and autoantibody profiles in patients with systemic lupus erythematosus
Gatto M; Depascale R; Cetrez N; Lindblom J; Nikolopoulos D; Doria A; Parodis I
Conference publication: 2024;:a86.1-a8a86
P62 Machine learning approaches for prediction of renal flares in systemic lupus erythematosus: knowledge-driven models outperformed data-driven models
Cetrez N; Lindblom J; Mutten RD; Nikolopoulos D; Parodis I
Review: FRONTIERS IN MEDICINE. 2023;10:1217147
Janus kinase inhibitors in systemic lupus erythematosus: implications for tyrosine kinase 2 inhibition
Nikolopoulos D; Parodis I
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2022;81:484
DISRUPTED HIPPOCAMPAL NEUROGENESIS MEDIATED BY IL-6 AND IL-18 INDUCE NEUROPSYCHIATRIC CHANGES IN MURINE LUPUS
Nikolopoulos D; Manolakou T; Polissidis A; Filia A; Koutmani Y; Boumpas D
Conference publication: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:635-636
EULAR RECOMMENDATION-BASED QUALITY INDICATORS (QIS) FOR SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): ELABORATION, FINAL SET, PERFORMANCE AND INITIAL VALIDATION
Chavatza K; Kostopoulou M; Nikolopoulos D; Gioti O; Togia K; Flouda S; Kapsala N; Kosmetatou M; Moysidou GS; Grivas A; Pieta A; Ntourou A; Rapsomaniki P; Gerogianni T; Tseronis D; Aggelakos M; Karageorgas T; Katsimpri P; Andreoli L; Aringer M; Boletis N; Doria A; Houssiau F; Jayne D; Mosca M; Svenungsson E; Tincani A; Bertsias G; Fanouriakis A; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:21.1-2122
HIPPOCAMPAL IMMUNE CELL TRAFFICKING AND A MYELOID PREDOMINANT INFLAMMATORY RESPONSE WITH ENHANCED ANTIGEN PRESENTATION AND DECREASED LEVELS OF NEUROTRANSMITTERS UNDERLY THE NEUROPSYCHIATRIC PHENOTYPE OF THE NZW/NZB MURINE LUPUS MODEL
Nikolopoulos D; Manolakou T; Filia A; Nakos-Bimpos M; Polissidis A; Boumpas D
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2021;80:439-440
COMBINED ANALYSIS OF METABOLIC AND TRANSCRIPTOMIC KIDNEY PROFILES OF NZW/B-F1 MURINE LUPUS UNCOVERS BIOLOGICAL MECHANISMS PRECEDING THE ONSET OF NEPHRITIS
Manolakou T; Tsiara I; Nikolopoulos D; Garantziotis P; Benaki D; Gikas E; Frangou E; Mikroa E; Boumpas D
Review: CURRENT VASCULAR PHARMACOLOGY. 2020;18(6):549-565
Cardiovascular Disease in Systemic Lupus Erythematosus: Recent Data on Epidemiology, Risk Factors and Prevention
Kostopoulou M; Nikolopoulos D; Parodis I; Bertsias G

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