Dasiel Oscar Borroto Escuela

Dasiel Oscar Borroto Escuela

Research Specialist
Visiting address: Solnavägen 9 - kvarter B8, 17165 Solna
Postal address: C4 Neurovetenskap, C4 Forskning Fuxe, 171 77 Stockholm
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About me

  • Understanding whether alterations in specific heteroreceptor complexes and
    their receptor-receptor interactions are associated with and/or play a role
    in brain disease development, e.g., depression
    In the past years, I have been focused on the study of GPCR-GPCR and GPCR-RTK
    receptor-receptor interactions in the CNS and the characterization of their
    interface interactions, especially on the implementation of new innovative
    tools and screening technologies* *to identify GPCR oligomerization (e.g.,
    RT-BRET, in situ PLA). A novel understanding of the pathophysiology of brain
    disease may take place based on pathological changes in discrete brain
    receptor heteromers. Therefore, I has been involved on understanding whether
    alterations in specific GPCR heteroreceptor complexes and their allosteric
    receptor-receptor interactions are associated with and/or play a role in
    pathogenetic mechanisms contributing to brain disease development, inter alia
    Parkinson's disease, Schizophrenia, addiction and depression. These homo and
    heteroreceptor complexes offer novel targets for treatment of psychiatry and
    neurological disorders.
    *ACADEMIC HONORS*
    2018-2023 Board member of the Ph.D. comission in Biomolecular and
    Health Sciences at the University of Urbino Carlo Bo, Urbino, Italy.
    2019 Chair of the FENS Regional Meeting Symposium " Understanding the
    role of GPCR heteroreceptor complexes in the neuronal networks of the brain
    in health and disease". Belgrade, July 10-14, 2019. Serbia
    2019 Co-chair of the Karolinska Institutet Neuroscience Network
    Symposium 2019. Brain integrative processing through Oligomeric receptor
    complexes. Nobel Forum, KI, November 25, 2019. Stockholm, Sweden.
    2015 Chair of the FENS Regional Meeting Symposium " The impact of
    receptor-receptor interactions on brain plasticity ". October 07-10, in
    Thessaloniki, Greece.
    *AWARDS AND PRIZES*
    2014 ECNP Fellowship Award. 27th ECNP Congress, 18-21 October,
    Berlin, Germany
    2014 Neuroscience Travel Award. iSAMS 2014, 1-6 Octuber 2014, Tokyo,
    Japan
    2014 FENS/IBRO travel grant. 9th FENS Forum of Neuroscience, Milano,
    Italy.
    2013 Young Fellowship Award. FEBS-YSF Congress. Saint Petersburg,
    Russia.
    2013 ESF-EMBO Grant. ESF-EMBO Conference on Protein-Protein
    Interactions.
    2012 Royal Swedish Academy of Sciences Postdoctoral fellow. KI,
    Stockholm, Sweden
    2012 IUBMB/FEBS Grant. 22nd IUBMB &
  • 37th FEBS Congress, Seville, Spain.
    2012 FENS/IBRO travel grant. 8th FENS, Barcelona, Spain.
    2011 Excellence Thesis Award of the Polytechnic University of
    Catalonia. Spain.
    2008 Technology Transfer Award. Barcelona, Spain.
    2006 Fellowship for Advanced Studies Abroad (BE). Geneva, Switzerland
    2008 PhD student Research Fellow from EU-ESF. Barcelona, Spain.
    2012* *M.B.A. Master of International Business. Pompeu Fabra
    University, Spain.
    2008* *Ph.D. in Polymers and Biopolymers. Polytechnic University of
    Catalonia, Spain.
    2003* *M.Sc. in Bioinformatics. Center for Genetic Engineering and
    Biotechnology, Cuba.
    2003* *B.S. in Biochemistry. College of Biological Science, University
    of Havana, Cuba.

Teaching

  • I have been acting as a main supervisor of eighteen graduate students (9 BSc,
    4 MSc, 4 PhD, 1 Postdoc). As a member of five international PhD thesis
    examination committee (Spain, Italy, Belgium).
    2015-2023: Guest Professor. PhD Programme of the Department of Earth, Life
    and Environmental Sciences, Universitá Degli Studio di Urbino Carlo Bo,
    Urbino, Italy.

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