Chandana Rao Prakash

About me

Masters Degree in Molecular and Medical Biology from Lund University, Sweden.
Bachelor of Engineering Degree in Biotechnology from PES University,
Bangalore, India.

My doctoral projects aim to understand the Lung-Brain axis in Multiple
Sclerosis with a focus on studying the impact of smoking and it's associated epigenetic changes in the lungs and brain of patients.
I am primarily interested in applying different omics methods and optimizing multi-omics techniques to understand epigenetic mechanisms driving the disease.

Article: GENOME BIOLOGY. 2026;27(1):52
Comprehensive profiling of CRISPR/dCas9 epigenome editors indicates a complex link between on and off target effects
Pahlevan Kakhki M; Rangani F; Ewing E; Starvaggi Cucuzza C; Zheleznyakova G; Kalomoiri M; Kenny L; Raghavan A; Rao Prakash C; van den Hoeven G; Venkata S. Badam T; Covacu R; Andreou I; Needhamsen M; Kular L; Jagodic M
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1251772
Simultaneous detection of DNA variation and methylation at HLA class II locus and immune gene promoters using targeted SureSelect Methyl-Sequencing
Kalomoiri M; Prakash CR; Lagstroem S; Hauschulz K; Ewing E; Shchetynsky K; Kular L; Needhamsen M; Jagodic M
Article: JOURNAL OF ASSISTED REPRODUCTION AND GENETICS. 2020;37(9):2137-2150
Culture of human ovarian tissue in xeno-free conditions using laminin components of the human ovarian extracellular matrix
Hao J; Tuck AR; Prakash CR; Damdimopoulos A; Sjodin MOD; Lindberg J; Niklasson B; Pettersson K; Hovatta O; Damdimopoulou P

Conference publication: EUROPEAN JOURNAL OF NEUROLOGY. 2026;33
Epigenetic modifications of cerebrospinal fluid cell-free DNA as a marker of neuronal damage
Cucuzza CS; Prakash CR; Nolan C; Simeone A; Sarre L; Charlesworth T; Puddu F; Han Y; Khademi M; Evertsson B; Fink K; Svenningsson P; Ingre C; Seitz C; Fang F; Thelin E; Kular L; Piehl F; Needhamsen M; Jagodic M
Preprint: BIORXIV. 2026
Transgenic dCas9-DNMT3A mouse lines enable ex vivo and in vivo methylation editing with locus-dependent transcriptional effects
Kalomoiri M; Sorini C; Vos S; Camargo A; Tsalikou A; Krstic A; Prakash CR; Svenningsson P; Needhamsen M; Pahlevan Kakhki M; Kular L; Jagodic M
Preprint: BIORXIV. 2026
Epigenomic profiling of cerebrospinal fluid cells identifies immune regulatory alterations and implicates protocadherins in multiple sclerosis
Han Y; Zheleznyakova GY; Sorini C; Kakhki MP; Ruffin N; Liang H; Hallen N; Prakash CR; Beckers V; Ivanova E; Khademi M; Karlsson MCI; Piehl F; Olsson T; Kelsey G; Kular L; Needhamsen M; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2025;31(3):1098
Exploration of small non-coding RNAs in Multiple Sclerosis
Rangani F; Kakhki MP; Prakash CR; Badam TVS; Ekman D; Sagir F; Piket E; Manouchehrinia A; Khademi M; Piehl F; Olsson T; Needhamsen M; Jagodic M

The role of Lung-Brain axis in Multiple Sclerosis development and Progression
Neuroförbundet