Caroline Nordenvall

Caroline Nordenvall

Affiliated to Research | Docent
Visiting address: Elite Hotell, plan 2, Eugeniavägen 6, 17176 Stockholm
Postal address: K1 Molekylär medicin och kirurgi, K1 MMK Kolorektalkirurgi, 171 76 Stockholm

About me

  • Caroline Nordenvall is an associate professor of surgery at Karolinska
    Institutet and clinically active colorectal surgeon at Karolinska University
    Hospital, Stockholm, Sweden. Nordenvall started with epidemiological research
    in 2002 and defended her thesis on risk factors for colorectal and anal
    cancer in 2010.
    Nordenvall became a board-certified surgeon in 2016 and an associate
    professor of surgery in the same year. After her PhD Nordenvall has continued
    with epidemiological and clinical research with a specific focus on
    inflammatory bowel disease (especially restorative surgery) and colorectal
    cancer. Since 2019 she is the head of the research group and responsible for
    the research field of colorectal surgery with special focus on clinical,
    translational and epidemiological studies on colorectal cancer. Since 2018,
    Nordenvall is the scientific secretary of the Swedish Society for Colorectal
    Surgeons, board member of the Swedish quality register for patients with IBD,
    as well as the register for patients with colorectal cancer. She supervise 11
    PhD students (4 as main supervisor) as well as 3 post docs.
    Research group leader of the group Colorectal Surgery [1]
    [1] http://ki.se/en/mmk/colorectal-surgery-0

Research

  • Caroline Nordenvall works as a colorectal surgeon in Colorectal cancer, Theme Cancer, Karolinska University Hospital. Nordenvall began research at the Department of Medical Epidemiology and Biostatistics, KI, 2002 and defended his thesis on risk factors for colorectal and anal cancer in 2010. She then joined the research group in Colorectal Surgery at MMK and has continued her research funded by, among others, two fellowships (SSMF, Ihre Fellowship) and clinical research position (Region Stockholm). Her areas of focus are surgical treatment of inflammatory bowel disease (IBD) and colorectal cancer. She thinks it´s incredible stimulating to combine research and clinic and is always curious on new projects. 


  • *IBD*
    Through national and international epidemiological studies, Nordenvall has studied the surgical treatment of patients with IBD. Her research have shown, among other things, that less than half of patients who have had colectomy undergoing reconstructive surgery, which has resulted in the CRUISE study (Colectomy and Reconstruction in Ulverative colitis in Sweden and England study) for which Nordenvall is the PI. The CRUISE study is a multicenter study in collaboration with Linköping, Gothenburg, St Marks Hospital and University Hospitals Birmingham. The aim of the study is to for the first time prospecitvely compare two different surgical methods in reconstructive surgery (ileorectal anastomosis and pelvic reservoir). In collaboration with docent Jenny Mjösberg the CIM-IBD study with immunological analyzes of IBD resectates is conducting. Nordenvall is also a member of the steering group for SWIBREG and Stockholms representative of the National Working Group for IBD (NAG-IBD). 


  • *Colorectal Cancer*
    The other area of interest is colorectal cancer. Nordenvall conducts clinical studies on advanced colon cancer, anal cancer and the sequel after rectal cancer treatment. In addition, she is on the steering committee for CRCBaSe (colorectal cancer quality registry linked to national registries) and conducts registry-based studies within megalinking https://cancercentrum.se/samverkan/cancerdiagnoser/tjocktarm-andtarm-och-anal/tjock--och-andtarm/kvalitetsregister/forskning/forskningsdatabas/.
    [1] Since two years ago, translational studies have been conducted on patients with colon cancer and metastatic colorectal cancer where the aim is to study the impact of the immune system on disease, treatment response and prognosis. [1] https://cancercentrum.se/samverkan/cancerdiagnoser/tjocktarm-andtarm-och-anal/tjock--och-andtarm/kvalitetsregister/forskning/forskningsdatabas/.

 
  • Articles

    All other publications

    Grants

    • Swedish Research Council
      1 January 2024 - 31 December 2026
    • Hur är den kirurgiska handläggningen av patienter med ulcerös kolit i Sverige och Finland?
      Martin Rind
      1 January 2018 - 31 December 2018
    • Hur är den kirurgiska handläggningen av patienter med ulcerös kolit i Sverige och Finland?
      Bengt Ihre Foundation
      1 January 2018 - 31 December 2018
    • Restorative surgery in patients with ulcerative colitis, register comparison studies and a multicentre international study
      KI fonder
      1 January 2018 - 31 December 2019
    • Hur påverkar den kirurgiska behandlingen av IBD progressen av PSC och vice versa?
      Ruth och Richard Julins fond
      1 January 2017 - 31 December 2017
    • Hur är den kirurgiska handläggningen av patienter med ulerös kolit i Sverige och England?
      Bengt Ihre´s fond
      1 January 2017 - 31 December 2017
    • The surgical treatment of patients with inflammatory bowel disease
      Bengt Ihre Research Fellowship
      1 January 2017 - 31 December 2018
    • Hur är den kirurgiska handläggningen av patienter med ulcerös kolit i olika länder?
      MagTarmfonden
      1 January 2016 - 31 December 2016
    • Hur är den kirurgiska handläggningen av patienter med ulcerös kolit i olika länder?
      KI fonder
      1 January 2016 - 31 December 2017
    • Komplikationer i samband med behandling för sköldkörtelcancer
      Serafimerlasarettet
      1 January 2015 - 31 December 2015
    • Komplikationer i samband med behandling för sköldkörtelcancer
      Martin Rinds Stiftelse
      1 January 2014 - 31 December 2014
    • Komplikationer i samband med behandling för sköldkörtelcancer
      Serafimerlasarettet
      1 January 2014 - 31 December 2014
    • Skadepanorama och bestående men, med fokus på skallskador, efter cykelolyckor hos cyklister med och utan hjälm
      Martin Rinds Stiftelse
      1 January 2014 - 31 December 2014
    • Mortalitet och morbiditet efter kolektomi hos patienter med ulcerös kolit och Mb Crohn
      Stiftelsen Serafimerlasarettet
      1 January 2013 - 31 December 2013
    • Skadepanorama och bestående men, med fokus på skallskador, efter cykelolyckor hos cyklister med och utan hjälm
      Tornspiran
      1 January 2013 - 31 December 2013
    • Mortalitet och morbiditet efter kolektomi hos patienter med ulcerös kolit och Mb Crohn
      KI fonder
      1 January 2013 - 1 January 2013
    • Hur går det för patienter med inflammatorisk tarmsjukdom efter att man opererat bort tjocktarmen (kolektomi)?
      Svenska Sällskapet för Medicinsk Forskning
      1 January 2013 - 31 December 2014
    • Mortaliteten efter akut och elektiv kolektomi hos patienter med Mb Crohn och ulcerös kolit
      Bengt Ihre
      1 January 2012 - 31 December 2012
    • Mortaliteten efter akut och elektiv kolektomi hos patienter med Mb Crohn och ulcerös kolit
      Tornspiran
      1 January 2012 - 1 January 2012

    Employments

    • Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-2025

    Degrees and Education

    • Docent, Karolinska Institutet, 2016
    • Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2010
    • University Medical Degree, Karolinska Institutet, 2006

    Supervisor

    • Emelie Wiktorsson, 2024
    • Sol Erika Boman, 2023
    • Ida Hed Myrberg, 2023
    • Emma Rosander, 2023
    • Erik Hallqvist Osterman, 2022
    • Erik Lundqvist, 2022
    • Cecilia Merk, 2022
    • Oda Rosvall, 2021
    • Malin Ljunggren, Metastatic colorectal cancer - identifying the patients that receive and benefit from treatment with curative intent, https://ki.se/en/people/malin-ljunggren, 2021
    • Mehrnoosh Shahrivar, Aspirin use, genetic profile and prognosis in patients with colorectal cancer, https://ki.se/en/people/mehrnoosh-shahrivar, 2020
    • Louise de la Motte, Sequele after multimodal treatment of rectal cancer, 2019
    • Anton Risto, 2019
    • Karin Westberg, 2019
    • Caroline Weibull, 2018
    • Aiva Båve Lundgren, 2018
    • Naseer Baloch, Perineal healing following abdominoperineal resection for rectal and anal cancer, 2017
    • Maximilian Zoltek, 2017
    • Emil Pienowski, Aspects of low anterior resection syndrome
    • prevalence, risk factors and treatment, 2017
    • Emma Rosander, Aspects of locally advanced colon cancer, 2015
    • Evelyne Zibung, Bicycle trauma and its consequences, 2015
    • Petri Rantanen, On the clinical evaluation of morhology related and other risk factors in colorectal cancer patients, 2014

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