Carl-Fredrik Bowin

Publications
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Public outreach and news

Articles

Article: SCIENCE SIGNALING. 2023;16(779):eabo4974
WNT stimulation induces dynamic conformational changes in the Frizzled-Dishevelled interaction
Bowin C-F; Kozielewicz P; Gratz L; Kowalski-Jahn M; Schihada H; Schulte G
Article: NATURE COMMUNICATIONS. 2021;12(1):3919
Residue 6.43 defines receptor function in class F GPCRs
Turku A; Schihada H; Kozielewicz P; Bowin C-F; Schulte G
Article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2021;4(3):1235-1245
Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments
Kozielewicz P; Shekhani R; Moser S; Bowin C-F; Wesslowski J; Davidson G; Schulte G
Article: NATURE COMMUNICATIONS. 2020;11(1):414
Structural insight into small molecule action on Frizzleds
Kozielewicz P; Turku A; Bowin C-F; Petersen J; Valnohova J; Canizal MCA; Ono Y; Inoue A; Hoffmann C; Schulte G
Article: MOLECULAR PHARMACOLOGY. 2020;97(1):23-34
A NanoBRET-Based Binding Assay for Smoothened Allows Real-time Analysis of Ligand Binding and Distinction of Two Binding Sites for BODIPY-cyclopamine
Kozielewicz P; Bowin C-F; Turku A; Schulte G
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(31):11677-11684
WNT-3A-induced β-catenin signaling does not require signaling through heterotrimeric G proteins
Bowin C-F; Inoue A; Schulte G
Article: NATURE COMMUNICATIONS. 2019;10(1):667
A conserved molecular switch in Class F receptors regulates receptor activation and pathway selection
Wright SC; Kozielewicz P; Kowalski-Jahn M; Petersen J; Bowin C-F; Slodkowicz G; Marti-Solano M; Rodriguez D; Hot B; Okashah N; Strakova K; Valnohova J; Babu MM; Lambert NA; Carlsson J; Schulte G

All other publications

Letter: CELL RESEARCH. 2021;31(12):1311-1314
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric G_s
Xu L; Chen B; Schihada H; Wright SC; Turku A; Wu Y; Han G-W; Kowalski-Jahn M; Kozielewicz P; Bowin C-F; Zhang X; Li C; Bouvier M; Schulte G; Xu F
Thesis / dissertation: 2021
WNT/Frizzled signaling : illuminating the road towards pathway selectivity
Bowin, Carl-Fredrik

Employments

Postdoctoral Researcher, Department of Clinical Neuroscience, Karolinska Institutet, 2022-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Physiology and Pharmacology, Karolinska Institutet, 2021

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