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About me

I am an associate professor of epidemiology at Drexel University in Philadelphia, PA. My etiological research focuses on environmental influences shaping neurologic development, especially with regard to autism spectrum disorders, using population-based registers and databases and historical biobanks. A separate theme of my research focuses on the methodological toolbox necessary for causal inference in epidemiology.  Specific interests include biomarker characterization in epidemiologic studies, machine learning and data mining, and optimization of propensity score techniques.

Education

2009 PhD Epidemiology, Johns Hopkins University

2006 MHS Epidemiology, Johns Hopkins University

2003 AB Biological Anthropology, Harvard College

Research description

Current research grants:

“Early life vitamin D levels and risk of autism spectrum disorders”

“Use of Selective Serotonin Reuptake Inhibitors in Pregnancy and Offspring Neurodevelopment”

“Risk Profiling of Pregnant Women for Targeted Screening for Alloimmunization.”

“The role of early life inflammation in the etiology of autism spectrum disorders: a longitudinal study based on a combination of register and bio-sample data”

Teaching portfolio

Applied Causal Inference

Publications

Brief Report: Examining the Association of Autism and Adverse Childhood Experiences in the National Survey of Children's Health: The Important Role of Income and Co-occurring Mental Health Conditions
Kerns Cm, Newschaffer Cj, Berkowitz S, Lee Bk
Journal of autism and developmental disorders 2017;47(7):2275-2281

Brief Report: Prevalence of Co-occurring Epilepsy and Autism Spectrum Disorder: The US National Survey of Children's Health 2011-2012
Thomas S, Hovinga Me, Rai D, Lee Bk
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 2017;47(1):224-229

Length of Storage of Red Blood Cells and Patient Survival After Blood Transfusion: A Binational Cohort Study
Halmin M, Rostgaard K, Lee Bk, Wikman A, Norda R, Nielsen Kr, et al
Annals of internal medicine 2017;166(4):248-256

Maternal hirsutism and autism spectrum disorders in offspring
Lee Bk, Arver S, Widman L, Gardner Rm, Magnusson C, Dalman C, et al
Autism research : official journal of the International Society for Autism Research 2017;10(9):1544-1546

Maternal Polycystic Ovary Syndrome and Risk for Attention-Deficit/Hyperactivity Disorder in the Offspring
Kosidou K, Dalman C, Widman L, Arver S, Lee Bk, Magnusson C, et al
Biological psychiatry 2017;82(9):651-659

The Changing Epidemiology of Autism Spectrum Disorders
Lyall K, Croen L, Daniels J, Fallin Md, Ladd-acosta C, Lee Bk, et al
Annual review of public health 2017;38():81-102

Umbilical cord blood androgen levels and ASD-related phenotypes at 12 and 36 months in an enriched risk cohort study
Park By, Lee Bk, Burstyn I, Tabb Lp, Keelan Ja, Whitehouse Ajo, et al
MOLECULAR AUTISM 2017;:3-

Associations of Parental Depression With Child School Performance at Age 16 Years in Sweden
Shen H, Magnusson C, Rai D, Lundberg M, Lê-scherban F, Dalman C, et al
JAMA psychiatry 2016;73(3):239-46

Haemolytic and nonhaemolytic neonatal jaundice have different risk factor profiles
Lee Bk, Le Ray I, Sun Jy, Wikman A, Reilly M, Johansson S
Acta paediatrica (Oslo, Norway : 1992) 2016;105(12):1444-1450

In utero Exposure to beta-2-Adrenergic Receptor Agonist Drugs and Risk for Autism Spectrum Disorders
Gidaya Nb, Lee Bk, Burstyn I, Michael Y, Newschaffer Cj, Mortensen El
PEDIATRICS 2016;137(2):e20151316-

Maternal Exposure to Occupational Asthmagens During Pregnancy and Autism Spectrum Disorder in the Study to Explore Early Development
Singer Ab, Windham Gc, Croen La, Daniels Jl, Lee Bk, Qian Ye, et al
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS 2016;46(11):3458-3468

Maternal polycystic ovary syndrome and the risk of autism spectrum disorders in the offspring: a population-based nationwide study in Sweden
Kosidou K, Dalman C, Widman L, Arver S, Lee Bk, Magnusson C, et al
Molecular psychiatry 2016;21(10):1441-8

Maternal vitamin D deficiency and the risk of autism spectrum disorders: population-based study
Magnusson C, Lundberg M, Lee Bk, Rai D, Karlsson H, Gardner R, et al
BJPsych open 2016;2(2):170-172

Presence of an epigenetic signature of prenatal cigarette smoke exposure in childhood
Ladd-acosta C, Shu C, Lee Bk, Gidaya N, Singer A, Schieve La, et al
ENVIRONMENTAL RESEARCH 2016;:139-148

Advancing parental age and autism: multifactorial pathways
Lee Bk, Mcgrath Jj
Trends in molecular medicine 2015;21(2):118-25

Caregiving frequency and physical function: the Women's Health Initiative
Rosso Al, Lee Bk, Stefanick Ml, Kroenke Ch, Coker Lh, Woods Nf, et al
The journals of gerontology. Series A, Biological sciences and medical sciences 2015;70(2):210-5

Changes in prevalence of autism spectrum disorders in 2001-2011: findings from the Stockholm youth cohort
Idring S, Lundberg M, Sturm H, Dalman C, Gumpert C, Rai D, et al
Journal of autism and developmental disorders 2015;45(6):1766-73

Evaluating Propensity Score Methods in a Quasi-Experimental Study of the Impact of Menu-Labeling
Mayne Sl, Lee Bk, Auchincloss Ah
PLOS ONE 2015;10(12):e0144962-

Mapping collaboration networks in the world of Autism Research
Goldstein Nd, Tager-flusberg H, Lee Bk
Autism research : official journal of the International Society for Autism Research 2015;8(1):1-8

Maternal body mass index during early pregnancy, gestational weight gain, and risk of autism spectrum disorders: Results from a Swedish total population and discordant sibling study
Gardner Rm, Lee Bk, Magnusson C, Rai D, Frisell T, Karlsson H, et al
International journal of epidemiology 2015;44(3):870-83

Maternal folate status as a risk factor for autism spectrum disorders: a review of existing evidence
Devilbiss Ea, Gardner Rm, Newschaffer Cj, Lee Bk
The British journal of nutrition 2015;114(5):663-72

Maternal hospitalization with infection during pregnancy and risk of autism spectrum disorders
Lee Bk, Magnusson C, Gardner Rm, Blomström Å, Newschaffer Cj, Burstyn I, et al
Brain, behavior, and immunity 2015;44():100-5

Maternal Smoking and Autism Spectrum Disorder: A Meta-analysis
Rosen Bn, Lee Bk, Lee Nl, Yang Y, Burstyn I
Journal of autism and developmental disorders 2015;45(6):1689-98

Occupational physical demand and risk of hip fracture in older women
Palumbo Aj, Michael Yl, Burstyn I, Lee Bk, Wallace R
Occupational and environmental medicine 2015;72(8):567-72

A no-cost geocoding strategy using R
Goldstein Nd, Auchincloss Ah, Lee Bk
Epidemiology (Cambridge, Mass.) 2014;25(2):311-3

Associations of Rhesus and non-Rhesus maternal red blood cell alloimmunization with stillbirth and preterm birth
Fan J, Lee Bk, Wikman At, Johansson S, Reilly M
International journal of epidemiology 2014;43(4):1123-31

Brief report: trends in US National autism awareness from 2004 to 2014: the impact of national autism awareness month
Devilbiss Ea, Lee Bk
Journal of autism and developmental disorders 2014;44(12):3271-3

Hospital admission with infection during childhood and risk for psychotic illness--a population-based cohort study
Blomström Å, Karlsson H, Svensson A, Frisell T, Lee Bk, Dal H, et al
Schizophrenia bulletin 2014;40(6):1518-25

In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder
Gidaya Nb, Lee Bk, Burstyn I, Yudell M, Mortensen El, Newschaffer Cj
Journal of autism and developmental disorders 2014;44(10):2558-67

Knowledge and attitudes about Parkinson's disease among a diverse group of older adults
Pan S, Stutzbach J, Reichwein S, Lee Bk, Dahodwala N
Journal of cross-cultural gerontology 2014;29(3):339-52

Parental age and the risk of autism spectrum disorders: findings from a Swedish population-based cohort
Idring S, Magnusson C, Lundberg M, Ek M, Rai D, Svensson Ac, et al
International journal of epidemiology 2014;43(1):107-15

Residential proximity to electromagnetic field sources and birth weight: Minimizing residual confounding using multiple imputation and propensity score matching
De Vocht F, Lee B
Environment international 2014;69():51-7

School performance and the risk of suicide attempts in young adults: a longitudinal population-based study
Kosidou K, Dalman C, Fredlund P, Lee Bk, Galanti R, Isacsson G, et al
Psychological medicine 2014;44(6):1235-43

Use of meconium in perinatal epidemiology: potential benefits and pitfalls
Park By, Lee Bk
Annals of epidemiology 2014;24(12):878-81

Neonatal levels of acute phase proteins and later risk of non-affective psychosis
Gardner Rm, Dalman C, Wicks S, Lee Bk, Karlsson H
Translational psychiatry 2013;3():e228-

Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based case-control study
Rai D, Lee Bk, Dalman C, Golding J, Lewis G, Magnusson C
BMJ (Clinical research ed.) 2013;346():f2059-

Prognostic score-based balance measures can be a useful diagnostic for propensity score methods in comparative effectiveness research
Stuart Ea, Lee Bk, Leacy Fp
Journal of clinical epidemiology 2013;66(8 Suppl):S84-S90.e1

Serum folate but not vitamin B-12 concentrations are positively associated with cognitive test scores in children aged 6-16 years
Nguyen Ct, Gracely Ej, Lee Bk
The Journal of nutrition 2013;143(4):500-4

Total blood mercury levels and depression among adults in the United States: National Health and Nutrition Examination Survey 2005-2008
Ng Th, Mossey Jm, Lee Bk
PloS one 2013;8(11):e79339-

ABO and RhD blood groups and gestational hypertensive disorders: a population-based cohort study
Lee Bk, Zhang Z, Wikman A, Lindqvist Pg, Reilly M
BJOG : an international journal of obstetrics and gynaecology 2012;119(10):1232-7

Autism spectrum disorders in the Stockholm Youth Cohort: design, prevalence and validity
Idring S, Rai D, Dal H, Dalman C, Sturm H, Zander E, et al
PloS one 2012;7(7):e41280-

Brief report: maternal smoking during pregnancy and autism spectrum disorders
Lee Bk, Gardner Rm, Dal H, Svensson A, Galanti Mr, Rai D, et al
Journal of autism and developmental disorders 2012;42(9):2000-5

Joint effects of obesity and vitamin D insufficiency on insulin resistance and type 2 diabetes: results from the NHANES 2001-2006
Kabadi Sm, Lee Bk, Liu L
Diabetes care 2012;35(10):2048-54

Presentation of study results: the authors' responsibility
Burstyn I, Lee B, Gidaya Nb, Yudell M
Environmental health perspectives 2012;120(9):A343-4

Constructing a population-based research database from routine maternal screening records: a resource for studying alloimmunization in pregnant women
Lee Bk, Ploner A, Zhang Z, Gryfelt G, Wikman A, Reilly M
PloS one 2011;6(11):e27619-

Neighborhood psychosocial environment, apolipoprotein E genotype, and cognitive function in older adults
Lee Bk, Glass Ta, James Bd, Bandeen-roche K, Schwartz Bs
Archives of general psychiatry 2011;68(3):314-21

Weight trimming and propensity score weighting
Lee Bk, Lessler J, Stuart Ea
PloS one 2011;6(3):e18174-

Epidemiologic research and Web 2.0--the user-driven Web
Lee Bk
Epidemiology (Cambridge, Mass.) 2010;21(6):760-3

Improving propensity score weighting using machine learning
Lee Bk, Lessler J, Stuart Ea
Statistics in medicine 2010;29(3):337-46

Apolipoprotein e genotype, cortisol, and cognitive function in community-dwelling older adults
Lee Bk, Glass Ta, Wand Gs, Mcatee Mj, Bandeen-roche K, Bolla Ki, et al
The American journal of psychiatry 2008;165(11):1456-64

Variation in season of birth in singleton and multiple births concordant for autism spectrum disorders
Lee Lc, Newschaffer Cj, Lessler Jt, Lee Bk, Shah R, Zimmerman Aw
Paediatric and perinatal epidemiology 2008;22(2):172-9

Associations of salivary cortisol with cognitive function in the Baltimore memory study
Lee Bk, Glass Ta, Mcatee Mj, Wand Gs, Bandeen-roche K, Bolla Ki, et al
Archives of general psychiatry 2007;64(7):810-8

Genetic enhancement of visual learning by activation of protein kinase C pathways in small groups of rat cortical neurons
Zhang Gr, Wang X, Kong L, Lu Xg, Lee B, Liu M, et al
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(37):8468-81

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3215 Market St
Philadelphia