Björn Fischler

Björn Fischler

Adjunct Professor | Docent
Visiting address: Enheten för pediatrik, Novum, Blickagången 6A, 14157 Huddinge
Postal address: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Pediatrik, 141 52 Huddinge
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About me

  • Adjunct Professor of Paediatrics specialising in liver diseases at the
    Department of Clinical Science, Intervention and Technology as of 1 January
    2021. Primary position: Senior consultant at the Astrid Lindgren Children’s
    Hospital, Karolinska University Hospital

Research

  • Björn Fischler’s research deals with liver disease in children,
    particularly different forms of cholestasis. His research is conducted within
    international networks and in collaboration with preclinical groups. Fischler
    has demonstrated an association between cytomegalovirus (CMV) infection and
    biliary atresia. He now intends to study whether anti-CMV medication can
    improve the severe prognosis.
    Fischler has planned and participated in an international clinical study
    showing that a new drug effectively mitigates the symptoms of the cholestatic
    condition PFIC and probably improves survival rates. The phase III study has
    recently been concluded and the drug has been licensed in Europe and USA. For
    another cholestatic disease, Alagille's syndrome, which also affects other
    organs as well as trhe immune system, Fischler is collaborating with Emma
    Andersson’s research group at KI, which has developed a mouse model. This,
    in combination with clinical data from patients, can be used to explain
    pathophysiologies and test new therapies.

Articles

All other publications

Employments

  • Adjunct Professor, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2021-2028

Degrees and Education

  • Docent, Karolinska Institutet, 2003
  • Doctor Of Philosophy, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 1998

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