Björn Fischler
Adjunct Professor | Docent
E-mail: bjorn.fischler@ki.se
Visiting address: Enheten för pediatrik, Novum, Blickagången 6A, 14157 Huddinge
Postal address: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Pediatrik, 141 52 Huddinge
About me
- Adjunct Professor of Paediatrics specialising in liver diseases at the
Department of Clinical Science, Intervention and Technology as of 1 January
2021. Primary position: Senior consultant at the Astrid Lindgren Children’s
Hospital, Karolinska University Hospital
Research
- Björn Fischler’s research deals with liver disease in children,
particularly different forms of cholestasis. His research is conducted within
international networks and in collaboration with preclinical groups. Fischler
has demonstrated an association between cytomegalovirus (CMV) infection and
biliary atresia. He now intends to study whether anti-CMV medication can
improve the severe prognosis.
Fischler has planned and participated in an international clinical study
showing that a new drug effectively mitigates the symptoms of the cholestatic
condition PFIC and probably improves survival rates. The phase III study has
recently been concluded and the drug has been licensed in Europe and USA. For
another cholestatic disease, Alagille's syndrome, which also affects other
organs as well as trhe immune system, Fischler is collaborating with Emma
Andersson’s research group at KI, which has developed a mouse model. This,
in combination with clinical data from patients, can be used to explain
pathophysiologies and test new therapies.
Articles
- Article: INFECTIOUS DISEASES. 2024;56(10):907-917
- Article: JPGN REP. 2024;5(3):303-308
- Article: HEPATOLOGY. 2024;79(6):1279-1292
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2024;78(4):957-972
- Article: ORPHANET JOURNAL OF RARE DISEASES. 2023;18(1):383
- Journal article: WFUMB ULTRASOUND OPEN. 2023;1(2):100024
- Article: PEDIATRIC TRANSPLANTATION. 2023;27(7):e14589
- Article: TRANSPLANTATION. 2023;107(11):2394-2405
- Journal article: JOURNAL OF HEPATOLOGY. 2023;78:s433
- Article: HEPATOLOGY COMMUNICATIONS. 2023;7(3):e0031
- Article: PEDIATRIC SURGERY INTERNATIONAL. 2023;39(1):117
- Article: JHEP REPORTS. 2023;5(2):100626
- Article: HEPATOLOGY. 2023;77(2):512-529
- Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(3):775
- Article: TRANSPLANT INTERNATIONAL. 2023;36:11729
- Article: EMBO MOLECULAR MEDICINE. 2022;14(12):e15809
- Article: ISCIENCE. 2022;25(10):105070
- Article: THE LANCET GASTROENTEROLOGY AND HEPATOLOGY. 2022;7(9):830-842
- Article: JOURNAL OF PERINATOLOGY. 2022;42(6):702-707
- Article: EUROSURVEILLANCE. 2022;27(19):2200370
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2022;74(3):338-347
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2022;74(3):e45-e56
- Article: JOURNAL OF CLINICAL MEDICINE. 2022;11(4):945
- Article: CELL TRANSPLANTATION. 2022;31:9636897211069900
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2021;73(5):630-635
- Article: CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY. 2021;45(5):101751
- Article: PEDIATRIC TRANSPLANTATION. 2021;25(6):e13993
- Article: AUSTRALASIAN JOURNAL OF ULTRASOUND IN MEDICINE. 2021;24(3):143-150
- Article: HEPATOLOGY. 2021;74(2):892-906
- Article: ELIFE. 2021;10:e60916
- Article: FRONTIERS IN PEDIATRICS. 2021;9:754941
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(1):141-148
- Article: GUT. 2020;69(12):2203-2213
- Article: INFECTIOUS DISEASES. 2020;52(11):776-785
- Article: CLINICAL TRANSPLANTATION. 2020;34(10):e14063
- Article: JOURNAL OF HEPATOLOGY. 2020;73(1):84-93
- Article: JOURNAL OF INTERNAL MEDICINE. 2020;287(5):534-545
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2020;70(5):711-717
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2020;70(4):527-538
- Article: TRANSPLANTATION. 2020;104(3):522-525
- Article: VACCINE. 2020;38(4):790-793
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2019;69(6):648-654
- Article: JOURNAL OF VIRAL HEPATITIS. 2019;26(8):961-968
- Article: ACTA ONCOLOGICA. 2019;58(7):997-1002
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2019;68(5):700-705
- Article: PEDIATRIC TRANSPLANTATION. 2019;23(1):e13327
- Article: JOURNAL OF PEDIATRIC SURGERY. 2018;53(8):1509-1515
- Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 2018;53(7):870-875
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2018;66(6):976-990
- Article: GASTROENTEROLOGY. 2018;154(4):1080-1095
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2018;66(3):505-515
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2018;66(2):345-360
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2018;66(2):334-344
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2018;66(1):106-111
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2017;65(6):608-612
- Article: ACTA RADIOLOGICA. 2017;58(11):1395-1399
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2017;65(3):e53-e59
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2017;64(6):864-868
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2017;64(1):154-168
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2017;64(1):76-82
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2016;63(2):288-294
- Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2016;35(6):708-710
- Article: AMERICAN JOURNAL OF TRANSPLANTATION. 2016;16(3):1021-1030
- Article: PEDIATRIC TRANSPLANTATION. 2016;20(1):96-104
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2015;60(6):702-707
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2015;104(5):479-484
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2015;60(4):550-561
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2015;60(3):408-420
- Article: THROMBOSIS RESEARCH. 2015;135(2):382-387
- Journal article: ARCHIVES OF DISEASE IN CHILDHOOD. 2014;99(Suppl 2):a8
- Article: TRANSFUSION. 2014;54(5):1366-1370
- Article: JOURNAL OF PEDIATRICS. 2013;163(5):1347-53.e1
- Article: VACCINE. 2013;31(40):4284-4286
- Article: THROMBOSIS RESEARCH. 2013;132(3):346-351
- Article: BRITISH JOURNAL OF DERMATOLOGY. 2013;168(6):1311-1315
- Article: EUROPEAN JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2013;25(2):152-158
- Article: PLOS ONE. 2013;8(7):e68031
- Article: JOURNAL OF CLINICAL AND EXPERIMENTAL HEPATOLOGY. 2012;2(4):315-322
- Article: JOURNAL OF PEDIATRICS. 2012;161(5):899-902
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2012;101(9):993-999
- Journal article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2012;101(9):1000
- Article: JOURNAL OF PEDIATRIC SURGERY. 2011;46(3):467-472
- Article: ACTA OPHTHALMOLOGICA. 2011;89(2):143-150
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2010;51(4):494-499
- Article: JOURNAL OF HEPATOLOGY. 2010;53(1):170-178
- Article: JOURNAL OF HEPATOLOGY. 2010;52(6):827-831
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2009;98(10):1600-1602
- Journal article: JOURNAL OF CROHN'S AND COLITIS. 2009;3(1):12
- Article: HUMAN MUTATION. 2009;30(2):E330-E337
- Article: PLOS ONE. 2009;4(4):e5321
- Article: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2008;27(9):800-807
- Article: PEDIATRIC TRANSPLANTATION. 2008;12(5):531-535
- Article: JOURNAL OF PEDIATRIC SURGERY. 2008;43(7):1312-1320
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2008;47(1):98-101
- Article: GASTROENTEROLOGY. 2008;134(4):1203-1214
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2007;96(11):1660-1664
- Article: JOURNAL OF INTERNAL MEDICINE. 2007;262(2):254-262
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2007;45(1):75-83
- Article: SEMINARS IN FETAL AND NEONATAL MEDICINE. 2007;12(3):168-173
- Article: HUMAN GENETICS. 2006;120(3):396-409
- Article: HEPATOLOGY. 2006;44(2):478-486
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2005;40(4):481-486
- Article: JOURNAL OF PEDIATRIC SURGERY. 2005;40(3):541-546
- Article: THROMBOSIS RESEARCH. 2005;116(3):185-197
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2004;39(Supplement 1):s129
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2004;39(S1):s129
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2004;93(3):368-371
- Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2004;36(3):182-185
- Article: PEDIATRIC TRANSPLANTATION. 2003;7(5):385-389
- Article: ACTA OPHTHALMOLOGICA. 2003;81(2):130-137
- Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2003;35(8):445-451
- Article: CLINICAL INFECTIOUS DISEASES. 2002;35(9):1027-1031
- Article: LAKARTIDNINGEN. 2002;99(41):4082-4083
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2002;35(3):400
- Article: JOURNAL OF PEDIATRICS. 2002;141(2):217-222
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2002;34(2):154-157
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2002;34(2):154-157
- Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2002;34(9):698-699
- Article: BJOG: AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. 2001;108(4):371-377
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2001;90(2):171-178
- Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2001;90(1):88-92
- Article: JOURNAL OF MEDICAL VIROLOGY. 2000;62(3):334-344
- Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2000;32(5):465-470
- Article: JOURNAL OF CLINICAL MICROBIOLOGY. 1999;37(12):4153-4155
- Article: LAKARTIDNINGEN. 1999;96(44):4795-4800
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1999;28(5):578
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1999;28(5):578
- Article: CLINICAL INFECTIOUS DISEASES. 1999;28(3):537-540
- Article: ARCHIVES OF DISEASE IN CHILDHOOD: FETAL AND NEONATAL EDITION. 1999;80(2):F130-F134
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1998;27(1):57-64
- Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1998;27(1):57-64
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1998;26(5):573
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1998;26(5):573
- Journal article: OBSTETRICAL AND GYNECOLOGICAL SURVEY. 1998;53(4):208-209.
- Article: JOURNAL OF INFECTIOUS DISEASES. 1997;176(1):281-285
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1997;24(4):488
- Article: TROPICAL MEDICINE AND INTERNATIONAL HEALTH. 1996;1(6):865-873
- Article: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 1996;28(4):353-356
- Journal article: PEDIATRIC NEPHROLOGY. 1994;8(1):81-82
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1993;17(4):464
- Journal article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1993;17(4):464
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All other publications
- Letter: VIRULENCE. 2024;15(1):2318582
- Letter: JOURNAL OF INFECTION. 2024;88(3):106127
- Letter: HEPATOLOGY COMMUNICATIONS. 2024;8(2):e0339
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2024;113(1):15-18
- Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:S971-S973
- Conference publication: JOURNAL OF HEPATOLOGY. 2023;78:S969-S970
- Conference publication: HEPATOLOGY. 2023;78:S121-S124
- Conference publication: HEPATOLOGY. 2023;78:S20-S23
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2022;111(9):1806-1807
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(10):2810-2811
- Preprint: BIORXIV. 2021
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2021;110(4):1289-1290
- Conference publication: HEPATOLOGY. 2021;74:1175A-1176A
- Conference publication: HEPATOLOGY. 2021;74(6):1387A-1389A
- Conference publication: PEDIATRIC RESEARCH. 2021;90(SUPPL 1):33
- Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:85
- Conference publication: TRANSPLANT INTERNATIONAL. 2021;34:87
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2020;109(12):2441-2442
- Review: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2020;71(2):176-183
- Letter: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2020;70(6):e137
- Review: INFECTIOUS DISEASES. 2020;52(1):1-22
- Conference publication: HEPATOLOGY. 2020;72:555A-556A
- Conference publication: HEPATOLOGY. 2020;72:878A-880A
- Conference publication: HEPATOLOGY. 2020;72:884A-886A
- Conference publication: HEPATOLOGY. 2020;72:882A-884A
- Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S536-S537
- Conference publication: JOURNAL OF HEPATOLOGY. 2020;73:S554-S555
- Other: CLINICAL CASE REPORTS. 2019;7(6):1133-1138
- Meeting abstract: JOURNAL OF HEPATOLOGY. 2019;70(1):E120
- Meeting abstract: JOURNAL OF HEPATOLOGY. 2019;70(1):e411
- Conference publication: HEPATOLOGY. 2019;70(6):1494A-1495A
- Book chapter: VIRAL HEPATITIS IN CHILDREN. 2019;p. 163-168
- Conference publication: HEPATOLOGY. 2019;70:48A-49A
- Conference publication: JOURNAL OF HEPATOLOGY. 2019;70(1):E121
- Book chapter: PEDIATRIC HEPATOLOGY AND LIVER TRANSPLANTATION. 2019;p. 57-66
- Conference publication: HEPATOLOGY. 2019;70:55A-56A
- Editorial comment: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2018;107(12):2212-2213
- Meeting abstract: JOURNAL OF HEPATOLOGY. 2018;68:S626-S627
- Meeting abstract: JOURNAL OF HEPATOLOGY. 2018;68:S632
- Conference publication: HEPATOLOGY. 2018;68:1045A-1046A
- Conference publication: HEPATOLOGY. 2018;68:1051A-1052A
- Conference publication: HEPATOLOGY. 2018;68:117A-118A
- Letter: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2017;64(3):e82
- Conference publication: TRANSPLANT INTERNATIONAL. 2017;30:17
- Conference publication: HEPATOLOGY. 2017;66:926A-927A
- Conference publication: TRANSPLANTATION. 2017;101(5):8-9
- Conference publication: HEPATOLOGY. 2017;66:646A-647A
- Conference publication: HEPATOLOGY. 2016;64:331A
- Meeting abstract: JOURNAL OF HEPATOLOGY. 2015;62:S824
- Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13:663
- Conference publication: PEDIATRIC TRANSPLANTATION. 2015;19:134
- Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13:667
- Review: CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY. 2014;38(4):415-418
- Meeting abstract: DIGESTIVE AND LIVER DISEASE. 2014;46:E102
- Conference publication: TRANSPLANTATION. 2014;98:299
- Review: CLINICS AND RESEARCH IN HEPATOLOGY AND GASTROENTEROLOGY. 2014;38(3):263-267
- Review: UGESKRIFT FOR LAEGER. 2014;176(8):V02130136
- Letter: LAKARTIDNINGEN. 2014;111(11):494-495
- Conference publication: AMERICAN JOURNAL OF TRANSPLANTATION. 2014;14:299
- Conference publication: HEPATOLOGY. 2013;58:370A
- Review: JOURNAL OF INTERNAL MEDICINE. 2012;272(3):201-223
- Review: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2012;44(7):502-521
- Book chapter: HEMATOLOGY, IMMUNOLOGY AND INFECTIOUS DISEASE: NEONATOLOGY QUESTIONS AND CONTROVERSIES. 2012;p. 219-235
- Conference publication: PEDIATRIC TRANSPLANTATION. 2011;15:86-87
- Conference publication: PEDIATRIC TRANSPLANTATION. 2011;15:84
- Conference publication: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2011;9:937
- Letter: PEDIATRIC INFECTIOUS DISEASE JOURNAL. 2010;29(11):1062
- Conference publication: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2010;50:E20
- Conference publication: HEPATOLOGY. 2009;50(4):418A-419A
- Review: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2009;41(6-7):389-402
- Conference publication: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2009;98:246
- Conference publication: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2008;154:43
- Book chapter: HEMATOLOGY, IMMUNOLOGY AND INFECTIOUS DISEASE. 2008;p. 231-247
- Review: SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES. 2008;40(6-7):436-450
- Letter: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2007;96(10):1551
- Conference publication: PEDIATRIC TRANSPLANTATION. 2007;11:97
- Conference publication: PEDIATRIC TRANSPLANTATION. 2007;11:64
- Conference publication: PEDIATRIC TRANSPLANTATION. 2007;11:63-64
- Published conference paper: JOURNAL OF INFECTIOUS DISEASES. 2005;192(11):1872-1879
- Review: EXPERT REVIEW OF VACCINES. 2005;4(5):725-738
- Conference publication: HEPATOLOGY. 2005;42(4):380A-381A
- Conference publication: HEPATOLOGY. 2004;40(4):471A
- Letter: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 2002;35(3):400
- Letter: LAKARTIDNINGEN. 2001;98(19):2370-2372
- Conference publication: HEPATOLOGY. 2001;34(4):531A
- Review: LAKARTIDNINGEN. 1997;94(10):845-851
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Employments
- Adjunct Professor, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 2021-2024
Degrees and Education
- Docent, Karolinska Institutet, 2003
- Doctor Of Philosophy, Department of Clinical Science, Intervention and Technology, Karolinska Institutet, 1998