Begum Horuluoglu

2023- Assistant Professor, Division of Rheumatology, Center for Molecular Medicine, KI

2019-2023: Postdoc, Division of Rheumatology, Center for Molecular Medicine, KI

2014-2019: PhD, Molecular Biology and Genetics, Bilkent University, Turkiye & National Cancer Instiute, NIH, USA (Graduate Partnership Program)

My research interest is to understand the immunological mechanisms that leads to autoimmunity. Having my PhD through a partnership programme between Bilkent University, Turkey, and the National Cancer Institute, National Institutes of Health, USA, I've gained a diverse academic background. With extensive training and research training in cancer immunology and autoimmunity my PhD thesis focused on investigating TLR agonists as a therapeutic tool for cancer and autoimmune diseases. Subsequently I joined Prof Ingrid Lundbergs research group to pursue my interest to understand the cellular mechanisms involved in autoimmune diseases and how we can develop targeted therapies. Our collaborative efforts extend across disciplines, working closely with e the Rheumatology Clinic (KS), T cell experts Assoc Prof Karine Chemin and Professor Vivianne Malmström, antibody engineering expert Assoc Prof Caroline Grönwall, and bioinformatics expert Assist Profe Lina Diaz Gallo.

Since August 2023, I've held the position of Assistant Professor within Prof Lundberg's group. My focus has been on integrating molecular techniques with bioinformatic approaches to gain deeper insights into disease pathogenesis in autoimmunity with a focus on myositis. I am currently the main supervisor of a PhD student, a postdoc and a research assistant dedicated to understand the molecular mechanisms of an autoimmune disease called myositis. We are using state of the art technologies such as in-situ hybridization and single cell sequencing along with classical molecular techniques like multi-paramter flow cytometry, ELISA, IHC/IF.
 
Research Support:
The Myositis Association (TMA)
Åke Wiberg Stiftelse
Alex and Eva Wallströms Stfitelse
Professor Nanna Svartz Stiftelse
Stiftelsen Konung Gustaf V:s 80-års fond
Reumatikerförbundet
KI Research Foundations

2024: R workshop for multi-color flow cytometry analysis, Workshop co-organizer, KI, Stockholm, Sweden
2023: Basic Inflammation 2705, Course co-organizer, KI, Stockholm, Sweden
2019-2020: Introduction to Basic Immunology, Mentor, KI, Stockholm, Sweden
2018: Journal Club for Summer Students, NCI, NIH, Frederick, USA
2012-2017: Graduate Teaching Assistant, Department of Molecular Biology and Genetics, Bilkent University, Ankara, Turkey
2008-2009: Student Teaching Assistant, Department of Chemistry, Istanbul Technical University, Istanbul, Turkey