Anne Örtqvist
About me
I am an associate professor of clinical epidemiology and a specialist in obstetrics and gynecology, affiliated with Professor Olof Stephansson's research group at the Clinical Epidemiology Division at the Department of Medicine, Solna. I earned my PhD in 2015 with a thesis named "Early life origins of asthma - genetic and environmental factors in twin and kin" at the Department of Medical Epidemiology and Biostatistics.
COURSES AND DEGREES2025, Board-certified obstetrician-gynecologist, the Swedish National Board of Health and Welfare
2024, Associate Professor (Docent) in Clinical Epidemiology, Karolinska Institutet (KI)2018, Licensed Medical Doctor, the Swedish National Board of Health and Welfare
2015, Doctoral degree (PhD), Dept. of Medical Epidemiology and Biostatistics, KI
2013, University Medical Degree (MD), KI
CURRENT POSITION
2025/04 - ongoing, 50% research at the Clinical Epidemiology Division, Dept of Medicine, Solna, KI, and 50% clinical work as a specialist in OB/GYN at Visby Lasarett, Gotland.
SELECTED ACADEMIC DISTINCTIONS AND OTHER MERITS
2011, Selected after nomination by the Swedish Nobel Foundation to represent Karolinska Institutet’s medical students at the ”61th Meeting of Nobel Laureates dedicated to Physiology/Medicine”, Lindau, Germany
2012, Recipient of Swedish Asthma and Allergy Foundation Scholarship, in memory of Kerstin Hejdenberg
2015, Recipient of Asklepiospriset, best published original paper by a medical student, Swedish Medical Association
2020-2022, Research and education representative at the board of Obstetrics and Gynaecologist under training (OGU), as well as national resident representative within the educational board at the Swedish Society of Obstetrics and Gynaecology (SFOG), including organization of a 2-day national congress for residents in OB/Gyn2020 – ongoing, board member of “Gotlands Forskningsfond”
2022 – ongoing, Academic Editor at scientific journal PLOS ONE
2022 – ongoing, reviewer of research grant applications for KI Fonder2022-2023, Co-chair of Junior Faculty at KEP, KI
2023, Recipient, Best short oral presentation of a scientific poster at the 42th Nordic Congresses of Obstetrics and Gynaecology, Trondheim2024, Associate Professor in Clinical Epidemiology, Department of Medicine, Solna, KI
Research
My main research focus is in infections, medication and vaccination during pregnancy. I am the principal investigator of a project focusing on maternal vaccination against pertussis, influenza, RS-virus and COVID-19 and subsequent outcomes for the mother and child in a project called Vaccination In Pregnancy study (VIPs).
I am also one of the project leaders of the Swedish node in a Scandinavian collaboration named "Scandinavian studies of COvid-19 in PrEgnancy" (SCOPE). SCOPE aims to study COVID-19 infection and vaccination during pregnancy in Sweden, Norway and Denmark. Since the start of the pandemic we have evaluated several aspects of infection and vaccination and subsequent maternal adverse outcomes as well as neonatal outcomes, including hypertension during pregnancy, miscarriage, preterm birth, vaccination uptake, and risk factors for infection among others.
Other research areas of interest focuses on health care determinants on pregnancy outcomes, and more specifically safe deliveries for both mother and child. We have studied the association between travel time to delivery unit and unplanned out-of-hospital birth, infant morbidity and mortality, as well as maternal outcomes such as spontaneous versus planned start (induction or elective cesarean section) of delivery.
My PhD-studies focused on the role of fetal growth and exposure to antibiotics, and the risk of developing asthma/lung function restriction. We have further investigated the potential role of early antibiotic exposure and the risk of developing very early onset inflammatory bowel disease. I have also worked with validation studies of asthma in the Swedish population-based registers.
Teaching
I am the main supervisor of PhD students Kévin Lasmi and Hanna Josefsson, Clinical Epidemiology Division, Deparment of Medicine, Solna, who will focus their doctoral education on epidemiological and qualitative aspects of vaccination in pregnancy.
I am also a co-supervisor to PhD student and midwife Silvia Segovia Chacón at the Clinical Pharmacoepidemiology unit, Department of Medicine, Solna, KI, and also to dr Jannica Smedberg, surgeon at Visby Lasarett, and PhD student at Uppsala University, Department of surgical sciences.
I was the course organizer and lecturer for the course in Scientific Education at Visby Lasarett between 2016-2022. I am also a seminar leader within the Research school in epidemiology for clinicians at KI, and a clinical supervisor of medical students from Uppsala University at their clinical course in ob/gyn at Visby Lasarett.
Articles
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2025;104(1):55-67Holowko N; Ladfors LV; Ortqvist AK; Ahlberg M; Stephansson O
- Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2024;39(10):1127-1138Magnus MC; Caspersen IH; Wensaas K-A; Eide HN; Ortqvist AK; Oakley L; Magnus P; Haberg SE
- Article: BMJ-BRITISH MEDICAL JOURNAL. 2024;386:e079364Magnus MC; Soderling J; Ortqvist AK; Andersen A-MN; Stephansson O; Haberg SE; Urhoj SK
- Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2024;331(5):396-407Norman M; Magnus MC; Soderling J; Juliusson PB; Naver L; Ortqvist AK; Haberg S; Stephansson O
- Article: BMJ PUBLIC HEALTH. 2023;1(1):e000314Magnus MC; Ortqvist AK; Urhoj SK; Aabakke A; Mortensen LH; Gjessing H; Nybo Andersen A-M; Stephansson O; Haberg SE
- Article: BRAIN COMMUNICATIONS. 2023;5(4):fcad213Kolbjer S; Munoz DAM; OIrtqvist AK; Pettersson M; Hammarsjo A; Anderlid B-M; Dahlin M
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102(6):681-689Ortqvist AK; Magnus MC; Aabakke AJM; Urhoj SK; Hansen AV; Andersen A-MN; Krebs L; Pettersson K; Haberg SE; Stephansson O
- Article: PUBLIC HEALTH. 2023;217:105-114Holowko N; Haas J; Ahlberg M; Stephansson O; Ortqvist A
- Article: NATURE HUMAN BEHAVIOUR. 2023;7(4):529-544Calvert C; Brockway MM; Zoega H; Miller JE; Been JV; Amegah AK; Racine-Poon A; Oskoui SE; Abok II; Aghaeepour N; Akwaowo CD; Alshaikh BN; Ayede AI; Bacchini F; Barekatain B; Barnes R; Bebak K; Berard A; Bhutta ZA; Brook JR; Bryan LR; Cajachagua-Torres KN; Campbell-Yeo M; Chu D-T; Connor KL; Cornette L; Cortes S; Daly M; Debauche C; Dedeke IOF; Einarsdottir K; Engjom H; Estrada-Gutierrez G; Fantasia I; Fiorentino NM; Franklin M; Fraser A; Gachuno OW; Gallo LA; Gissler M; Haberg SE; Habibelahi A; Haggstrom J; Hookham L; Hui L; Huicho L; Hunter KJ; Huq S; Ashish KC; Kadambari S; Kelishadi R; Khalili N; Kippen J; Le Doare K; Llorca J; Magee LA; Magnus MC; Man KKC; Mburugu PM; Mediratta RP; Morris AD; Muhajarine N; Mulholland RH; Bonnard LN; Nakibuuka V; Nassar N; Nyadanu SD; Oakley L; Oladokun A; Olayemi OO; Olutekunbi OA; Oluwafemi RO; Ogunkunle TO; Orton C; Ortqvist AK; Ouma J; Oyapero O; Palmer KR; Pedersen LH; Pereira G; Pereyra I; Philip RK; Pruski D; Przybylski M; Quezada-Pinedo HG; Regan AK; Rhoda NR; Rihs TA; Riley T; Rocha TAH; Rolnik DL; Saner C; Schneuer FJ; Souter VL; Stephansson O; Sun S; Swift EM; Szabo M; Temmerman M; Tooke L; Urquia ML; von Dadelszen P; Wellenius GA; Whitehead C; Wong ICK; Wood R; Wroblewska-Seniuk K; Yeboah-Antwi K; Yilgwan CS; Zawiejska A; Sheikh A; Rodriguez N; Burgner D; Stock SJ; Azad MB
- Article: BMJ MEDICINE. 2023;2(1):e000465Ortqvist AK; Magnus MC; Dahlqvist E; Soderling J; Johansson K; Sandstroem A; Haberg SE; Stephansson O
- Article: SCIENTIFIC REPORTS. 2022;12(1):20625Magnus MC; Oakley LL; Hansen AV; Ortqvist AK; Petersen TG; Mortensen LH; Bliddal M; Andersen A-MN; Stephansson O; Haberg SE
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2022;101(10):1146-1152Hellsing C; Ortqvist AK; Hagel E; Mesas-Burgos C; Gustafsson UO; Granstrom AL
- Article: BMC MEDICAL EDUCATION. 2022;22(1):602Wadell M; Ortqvist AK; Linden K; Akerstrom M; Andersson O; Carlsson Y; Graner S; Jonsson M; Naurin E; Sengpiel V; Veje M; Wessberg A; Zaigham M
- Article: VACCINE. 2022;40(33):4686-4692Ortqvist AK; Dahlqwist E; Magnus MC; Ljung R; Jonsson J; Aronsson B; Pasternak B; Haberg SE; Stephansson O
- Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2022;227(2):287.e1-287.e17Tsamantioti E; Lisonkova S; Muraca G; Ortqvist AK; Razaz N
- Article: SCIENTIFIC REPORTS. 2022;12(1):8355Ortqvist AK; Magnus MC; Soderling J; Oakley L; Andersen A-MN; Haberg SE; Stephansson O
- Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 2022;327(15):1469-1477Magnus MC; Ortqvist AK; Dahlqwist E; Ljung R; Skar F; Oakley L; Macsali F; Pasternak B; Gjessing HK; Haberg SE; Stephansson O
- Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2022;226(4):550.e1-550.e22Oakley LL; Ortqvist AK; Kinge J; Hansen AV; Petersen TG; Soderling J; Telle KE; Magnus MC; Mortensen LH; Andersen A-MN; Stephansson O; Haberg SE
- Article: JAMA NETWORK OPEN. 2022;5(1):e2143947Mantel A; Ortqvist AK; Hirschberg AL; Stephansson O
- Article: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2021;100(8):1478-1489Ortqvist AK; Haas J; Ahlberg M; Norman M; Stephansson O
- Article: PEDIATRIC ALLERGY AND IMMUNOLOGY. 2021;32(4):709-719Hedman AM; Kuja-Halkola R; Ortqvist AK; van Hage M; Almqvist C; Nordlund B
- Article: LANCET GASTROENTEROLOGY & HEPATOLOGY. 2020;5(11):986-995Nguyen LH; Ortqvist AK; Cao Y; Simon TG; Roelstraete B; Song M; Joshi AD; Staller K; Chan AT; Khalili H; Olen O; Ludvigsson JF
- Article: PLOS ONE. 2019;14(12):e0227091Brew BK; Chiesa F; Lundholm C; Ortqvist A; Almqvist C
- Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2019;143(6):2062-2074Reese SE; Xu C-J; den Dekker HT; Lee MK; Sikdar S; Ruiz-Arenas C; Merid SK; Rezwan FI; Page CM; Ullemar V; Melton PE; Oh SS; Yang IV; Burrows K; Soderhall C; Jima DD; Gao L; Arathimos R; Kupers LK; Wielscher M; Rzehak P; Lahti J; Laprise C; Madore A-M; Ward J; Bennett BD; Wang T; Bell DA; Vonk JM; Haberg SE; Zhao S; Karlsson R; Hollams E; Hu D; Richards AJ; Bergstrom A; Sharp GC; Felix JF; Bustamante M; Gruzieva O; Maguire RL; Gilliland F; Baiz N; Nohr EA; Corpeleijn E; Sebert S; Karmaus W; Grote V; Kajantie E; Magnus MC; Ortqvist AK; Eng C; Liu AH; Kull I; Jaddoe VWV; Sunyer J; Kere J; Hoyo C; Annesi-Maesano I; Arshad SH; Koletzko B; Brunekreef B; Binder EB; Raikkonen K; Reischl E; Holloway JW; Jarvelin M-R; Snieder H; Kazmi N; Breton CV; Murphy SK; Pershagen G; Maria Anto J; Relton CL; Schwartz DA; Burchard EG; Huang R-C; Nystad W-C; Almqvist C; Henderson AJ; Melen E; Duijts L; Koppelman GH; London SJ
- Article: NATURE COMMUNICATIONS. 2019;10(1):1893Kupers LK; Monnereau C; Sharp GC; Yousefi P; Salas LA; Ghantous A; Page CM; Reese SE; Wilcox AJ; Czamara D; Starling AP; Novoloaca A; Lent S; Roy R; Hoyo C; Breton CV; Allard C; Just AC; Bakulski KM; Holloway JW; Everson TM; Xu C-J; Huang R-C; van der Plaat DA; Wielscher M; Merid SK; Ullemar V; Rezwan FI; Lahti J; van Dongen J; Langie SAS; Richardson TG; Magnus MC; Nohr EA; Xu Z; Duijts L; Zhao S; Zhang W; Plusquin M; DeMeo DL; Solomon O; Heimovaara JH; Jima DD; Gao L; Bustamante M; Perron P; Wright RO; Hertz-Picciotto I; Zhang H; Karagas MR; Gehring U; Marsit CJ; Beilin LJ; Vonk JM; Jarvelin M-R; Bergstrom A; Ortqvist AK; Ewart S; Villa PM; Moore SE; Willemsen G; Standaert ARL; Haberg SE; Sorensen TIA; Taylor JA; Raikkonen K; Yang IV; Kechris K; Nawrot TS; Silver MJ; Gong YY; Richiardi L; Kogevinas M; Litonjua AA; Eskenazi B; Huen K; Mbarek H; Maguire RL; Dwyer T; Vrijheid M; Bouchard L; Baccarelli AA; Croen LA; Karmaus W; Anderson D; de Vries M; Sebert S; Kere J; Karlsson R; Arshad SH; Hamalainen E; Routledge MN; Boomsma DI; Feinberg AP; Newschaffer CJ; Govarts E; Moisse M; Fallin MD; Melen E; Prentice AM; Kajantie E; Almqvist C; Oken E; Dabelea D; Boezen HM; Melton PE; Wright RJ; Koppelman GH; Trevisi L; Hivert M-F; Sunyer J; Munthe-Kaas MC; Murphy SK; Corpeleijn E; Wiemels J; Holland N; Herceg Z; Binder EB; Smith GD; Jaddoe VWV; Lie RT; Nystad W; London SJ; Lawlor DA; Relton CL; Snieder H; Felix JF
- Article: GUT. 2019;68(2):218-225Örtqvist AK; Lundholm C; Halfvarson J; Ludvigsson JF; Almqvist C
- Article: TWIN RESEARCH AND HUMAN GENETICS. 2017;20(5):380-388Lindemalm C; Nordlund B; Ortqvist AK; Lundholm C; van Hage M; Gong T; Almqvist C
- Article: TWIN RESEARCH AND HUMAN GENETICS. 2017;20(4):330-337Nordlund B; Lundholm C; Ullemar V; van Hage M; Ortqvist AK; Almqvist C
- Article: ANNALS OF THE AMERICAN THORACIC SOCIETY. 2017;14(7):1147-1153Ortqvist AK; Ullemar V; Lundholm C; Kuja-Halkola R; Magnusson PKE; Lichtenstein P; Hallberg J; Almqvist C
- Article: PLOS ONE. 2016;11(10):e0164126Ahlén KM; Örtqvist AK; Gong T; Wallas A; Ye W; Lundholm C; Almqvist C
- Article: JAMA PEDIATRICS. 2015;169(11):e153219Fall T; Lundholm C; Örtqvist AK; Fall K; Fang F; Hedhammar Å; Kämpe O; Ingelsson E; Almqvist C
- Article: TWIN RESEARCH AND HUMAN GENETICS. 2015;18(3):256-265Ullemar V; Lundholm C; Örtqvist AK; Gumpert CH; Anckarsäter H; Lundström S; Almqvist C
- Article: TWIN RESEARCH AND HUMAN GENETICS. 2015;18(3):273-280Almqvist C; Örtqvist AK; Ullemar V; Lundholm C; Lichtenstein P; Magnusson PKE
- Article: ACTA PAEDIATRICA. 2015;104(4):392-395Almqvist C; Örtqvist AK; Gong T; Wallas A; Ahlén KM; Ye W; Lundholm C
- Article: BMJ-BRITISH MEDICAL JOURNAL. 2014;349:g6979Örtqvist AK; Lundholm C; Kieler H; Ludvigsson JF; Fall T; Ye W; Almqvist C
- Journal article: CLINICAL AND TRANSLATIONAL ALLERGY. 2014;4(Suppl 1):o1Örtqvist AK; Lundholm C; Wettermark B; Ludvigsson JF; Ye W; Almqvist C
- Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2013;22(8):850-860Örtqvist AK; Lundholm C; Wettermark B; Ludvigsson JF; Ye W; Almqvist C
- Article: CLINICAL AND EXPERIMENTAL ALLERGY. 2010;40(7):1044-1053Lundholm C; Ortqvist AK; Lichtenstein P; Cnattingius S; Almqvist C
- Article: PEDIATRICS. 2009;124(4):e737-e743Ortqvist AK; Lundholm C; Carlstrom E; Lichtenstein P; Cnattingius S; Almqvist C
- Show more
All other publications
- Letter: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2024;231(3):e99-e100Magnus MC; Rasmussen TD; Ortqvist AK; Oakley LL; Urhoj SK; Stephansson O; Haberg SE
- Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:53Ortqvist AK; Magnus MC; Dahlqvist E; Soderling J; Johansson K; Sandstrom A; Haberg SE; Stephansson O
- Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:87Wadell M; Ortqvist A; Linden K; Akerstrom M; Andersson O; Carlsson Y; Graner S; Jonsson M; Naurin E; Sengpiel V; Veje M; Wessberg A; Zaigham M
- Conference publication: ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA. 2023;102:46Ortqvist AK; Magnus MC; Aabakke AJM; Hansen AV; Urhoj SK; Andersen A-MN; Krebs L; Pettersson K; Haberg SE; Stephansson O
- Conference publication: BEHAVIOR GENETICS. 2019;49(6):494Hedman A; Kuja-Halkola R; Ortqvist A; van Hage M; Almqvist C; Nordlund B
- Letter: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE. 2017;5(5):1451-1454.e4Örtqvist AK; Lundholm C; Fang F; Fall T; Almqvist C
- Letter: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2016;31(3):331-332Ludvigsson JF; Lundholm C; Örtqvist AK; Almqvist C
- Doctoral thesis: 2015Örtqvist A
- Review: CLINICAL AND EXPERIMENTAL ALLERGY. 2012;42(10):1430-1447Tedner SG; Örtqvist AK; Almqvist C
- Conference publication: ALLERGY. 2009;64:92Lundholm C; Ortqvist A; Lichtenstein P; Cnattingius S; Almqvist C
Grants
- Vaccination in pregnancy study (VIPs) – studies of vaccine uptake, safety and effectiveness in mother and childSwedish Research Council for Health, Working Life and Welfare1 January 2025 - 31 December 2027
- Vaccination In Pregnancy (VIP)Svenska Sällskapet för Medicinsk Forskning (SSMF) starting grant1 January 2025 - 31 December 2028
- Epidemiological and qualitative studies on uptake and safety of pertussis vaccination in pregnancy in SwedenKarolinska Institutet (KID)1 January 2025 - 31 December 2028
- Swedish Research Council for Health Working Life and Welfare1 January 2025 - 31 December 2027Research problem and specific questionsInfants are at risk of contracting severe respiratory infections such as whooping cough and infection with respiratory syncytial virus (RSV). Vaccination of pregnant women induces a vaccine-specific immune response with the formation of antibodies that pass across the placenta to the fetus, thus protecting the child from potentially life-threatening infections. We plan to investigate factors related to the uptake of pertussis and RSV vaccination in pregnancy, as well as the safety and effectiveness of the vaccines.Data and methodBy studying data from population-based national registers of all women who have given birth in Sweden since 2014 (>1 million mother-child pairs) with information on socio-economics, origin, vaccinations, diagnoses, medications, congenital malformations and deaths, we will study rare but serious side effects of the vaccines, their effectiveness and factors influencing vaccination uptake among pregnant women. In order to increase knowledge and understanding of pregnant women´s reluctance and motivation for vaccination, individual interviews with vaccinated and unvaccinated pregnant women, as well as focus group discussions with healthcare professionals, who encounter these women, will be conducted.Societal relevance and utilizationVaccination during pregnancy can reduce and prevent severe illness and death in children. At the same time, we know that vaccination uptake is influenced by socio-economic, cultural and regional factors, which can lead to unequal social conditions when it comes to the burden of disease. Further, pregnant women need to know that the vaccines are safe and effective. In this project, we have a unique opportunity to use family- and population-based, as well as qualitative data to answer these questions and thus contribute to the maintenance of society´s trust in vaccinations, customize interventions to increase vaccination uptake and reduce the burden of disease in an equal way in society.Plan for project realizationThe epidemiological analyses regarding whooping cough, as well as the qualitative study will begin in 2025. Data extraction for RSV studies will be initiated in 2025 and analyses will begin in 2026. The costs for the project consist of data extraction from national registers, implementation of the qualitative study, salaries for the applicant, co-applicants, biostatistician, as well as for a doctoral student and a post-doc, who will be recruited in 2025.
- Vaccination during pregnancy in Sweden – who, when and why?Åke Wiberg Foundation1 December 2024 - 31 December 2025
- Swedish Research Council for Health Working Life and Welfare1 January 2020 - 31 December 2022
Employments
- Resident, Obstetrics and Gynecology, Obstetrics and Gynecology, Visby lasarett, 2018-
- Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2025
Degrees and Education
- Board-certified obstetrician-gynecologist, Obstetrics and gynecology, National Board of Health and Welfare, 2025
- Docent, Clinical Epidemiology, Karolinska Institutet, 2024
- Degree Of Doctor Of Philosophy, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2015
- Degree Of Master Of Science In Medicine, Karolinska Institutet, 2013