Anna-Klara Rundlöf

Publications
CV
Public outreach and news

Articles

Article: ANTIOXIDANTS AND REDOX SIGNALING. 2013;18(7):795-799
Is Trichloroacetic Acid an Insufficient Sample Quencher of Redox Reactions?
Curbo S; Reiser K; Rundlof A-K; Karlsson A; Lundberg M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2013;430(1):90-94
Simvastatin inhibits the core promoter of the TXNRD1 gene and lowers cellular TrxR activity in HepG2 cells
Ekstrom L; Johansson M; Monostory K; Rundlof A-K; Arner ESJ; Bjorkhem-Bergman L
Article: BIOCHEMICAL PHARMACOLOGY. 2012;84(5):712-721
Inhibition of sphingosine kinase 1 enhances cytotoxicity, ceramide levels and ROS formation in liver cancer cells treated with selenite
Chatzakos V; Rundlof AK; Ahmed D; de Verdier PJ; Flygare J
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(11):1620-1629
Interaction of selenite and tellurite with thiol-dependent redox enzymes: Kinetics and mitochondrial implications
Rigobello MP; Folda A; Citta A; Scutari G; Gandin V; Fernandes AP; Rundloef A-K; Marzano C; Bjoernstedt M; Bindoli A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2009;47(6):710-721
Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift
Rigobello MP; Gandin V; Folda A; Rundlof A-K; Fernandes AP; Bindoli A; Marzano C; Bjornstedt M
Article: CANCER LETTERS. 2009;282(1):116-123
Selenite is a potent cytotoxic agent for human primary AML cells
Olm E; Jonsson-Videsater K; Ribera-Cortada I; Fernandes AP; Eriksson LC; Lehmann S; Rundlof A-K; Paul C; Bjornstedt M
Article: HISTOPATHOLOGY. 2009;55(3):313-320
Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation
Fernandes AP; Capitanio A; Selenius M; Brodin O; Rundlof A-K; Bjornstedt M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2009;106(27):11400-11405
Extracellular thiol-assisted selenium uptake dependent on the x_c^- cystine transporter explains the cancer-specific cytotoxicity of selenite
Olm E; Fernandes AP; Hebert C; Rundlof A-K; Larsen EH; Danielsson O; Bjornstedt M
Article: JOURNAL OF EXPERIMENTAL AND CLINICAL CANCER RESEARCH. 2009;28(1):92
Phenotype-dependent apoptosis signalling in mesothelioma cells after selenite exposure
Nilsonne G; Olm E; Szulkin A; Mundt F; Stein A; Kocic B; Rundlof A-K; Fernandes AP; Bjornstedt M; Dobra K
Article: THE FEBS JOURNAL. 2009;276(2):532-540
Effects of the antioxidant Pycnogenol^® on cellular redox systems in U1285 human lung carcinoma cells
Gandin V; Nystrom C; Rundlof A-K; Jonsson-Videsater K; Schonlau F; Horkko J; Bjornstedt M; Fernandes AP
Article: BIOCHEMICAL PHARMACOLOGY. 2008;75(11):2092-2099
Treatment of lung cancer cells with cytotoxic levels of sodium selenite:: Effects on the thioredoxin system
Selenius M; Fernandes AP; Brodin O; Bjornstedt M; Rundlof A-K
Article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2007;459(2):178-188
Differential regulation of expression of cytosolic and mitochondrial thioredoxin reductase in rat liver and kidney
Crosley LK; Meplan C; Nicol F; Rundlof AK; Arner ESJ; Hesketh JE; Arthur JR
Article: DIFFERENTIATION. 2007;75(2):123-132
Quantification of alternative mRNA species and identification of thioredoxin reductase 1 isoforms in human tumor cells
Rundlof A-K; Fernandes AP; Selenius M; Babic M; Shariatgorji M; Nilsonne G; Ilag LL; Dobra K; Bjornstedt M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2006;41(6):874-885
Selenite induces apoptosis in sarcomatoid malignant mesothelioma cells through oxidative stress.
Nilsonne G; Sun X; Nyström C; Rundlöf A-K; Potamitou Fernandes A; Björnstedt M; Dobra K
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2004;37(1):71-85
Thioredoxin reductase 1 is upregulated in atherosclerotic plaques:: Specific induction of the promoter in human macrophages by oxidized low-density lipoproteins
Furman C; Rundlöf AK; Larigauderie G; Jaye M; Bricca G; Copin C; Kandoussi AM; Fruchart JC; Arnér ESJ; Rouis M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2004;36(5):641-656
Evidence for intriguingly complex transcription of human thioredoxin reductase 1
Rundlöf AK; Janard M; Miranda-Vizuete A; Arnér ESJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(32):30542-30551
The core promoter of human thioredoxin reductase 1
Rundlöf AK; Carlsten M; Arnér ESJ
Article: BIOCHEMICAL JOURNAL. 2000;347(Pt 3):661-668
Prominent expression of the selenoprotein thioredoxin reductase in the medullary rays of the rat kidney and thioredoxin reductase mRNA variants differing at the 5′untranslated region
Rundlöf AK; Carlsten M; Giacobini MMJ; Arnér ESJ
Article: MOLECULAR GENETICS AND GENOMICS. 1999;260(6):603-607
Either of the chromosomal tuf genes of E. coli K-12 can be deleted without loss of cell viability.
Zuurmond AM; Rundlöf AK; Kraal B

All other publications

Review: ANTIOXIDANTS AND REDOX SIGNALING. 2010;12(7):867-880
Selenium and the Selenoprotein Thioredoxin Reductase in the Prevention, Treatment and Diagnostics of Cancer
Selenius M; Rundlof A-K; Olm E; Fernandes AP; Bjornstedt M
Meeting abstract: EJC SUPPLEMENTS. 2007;5(4):369
Selenite mediated cytotoxcicity in human lung cancer and the role of thioredoxin reductase 1
Fernandes AP; Selenius M; Capitanio A; Brodin O; Bjornstedt M; Rundlof AK
Meeting abstract: EJC SUPPLEMENTS. 2007;5(4):347
Selenite is a superior cytotoxic agent to human primary leukemia cells
Olm E; Jonsson-Videsaler K; Rundlof AK; Fernandes AP; Ribera I; Eriksson L; Paul C; Bjornstedt M
Meeting abstract: LUNG CANCER. 2006;54:S52
Targeting thioredoxin reductase -: a possible new treatment for malignant mesothelioma
Nilsonne G; Stein A; Rundloef A-K; Fernandes AP; Bjoernstedt M; Hjerpe A; Dobra K
Review: ANTIOXIDANTS AND REDOX SIGNALING. 2004;6(1):41-52
Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events
Rundlöf AK; Arnér ESJ
Thesis / dissertation: 2003
Expression of thioredoxin reductase 1 in mammalian cells with regulation by the core promoter and use of alternative splice variants
Rundlöf, Anna-Klara
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):291
The thioredoxin reductase/thioredoxin system is upregulated in atherosclerotic plaques:: Specific induction in human macrophages by oxidized low density lipoproteins
Furman C; Rundlöf AK; Jaye M; Searfoss G; Yue KT; Larigauderie G; Copin C; Kandoussi AM; Fruchart JC; Arnér ESJ; Rouis M

Employments

Senior Lecturer, Teaching and learning, Karolinska Institutet, 2023-

Degrees and Education

Docent, Karolinska Institutet, 2012
Doctor Of Philosophy, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2003

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