Ann-Charlotte Björklund

Publications
Public outreach and news

Articles

Article: SCIENTIFIC REPORTS. 2024;14(1):4000
Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia
Bwanika HC; Leo IR; Struyf N; Talanti A; Aswad L; Konnur A; Bjoerklund A-C; Heyman M; Rassidakis G; Erkers T; Seashore-Ludlow B; Jafari R; Pokrovskaja Tamm K
Article: CANCER RESEARCH. 2024;84(2):211-225
Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts
Moura PL; Mortera-Blanco T; Hofman IJ; Todisco G; Kretzschmar WW; Bjoerklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Cabrerizo Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead AJ; Lundin V; Dimitriou M; Yoshizato T; Woll PS; Ogawa S; Sandberg R; Jacobsen SEW; Hellstrom-Lindberg E
Article: CLINICAL CANCER RESEARCH. 2023;29(20):4256-4267
Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts
Todisco G; Creignou M; Bernard E; Bjorklund A-C; Moura PL; Tesi B; Mortera-Blanco T; Sander B; Jansson M; Walldin G; Barbosa I; Reinsbach SE; Hofman IJ; Nilsson C; Yoshizato T; Dimitriou M; Chang D; Olafsdottir S; Larsson SV; Tobiasson M; Malcovati L; Woll P; Jacobsen SEW; Papaemmanuil E; Hellstroem-Lindberg E
Article: FASEB JOURNAL. 2021;35(5):e21476
RNAi prodrugs decrease elevated mRNA levels of Polo-like kinase 1 in ex vivo cultured primary cells from pediatric acute myeloid leukemia patients
Kolosenko I; Goroshchuk O; Vidarsdottir L; Bjorklund A-C; Dowdy SF; Palm-Apergi C
Article: SCIENTIFIC REPORTS. 2020;10(1):2688
Targeting Plk1 with siRNNs in primary cells from pediatric B-cell acute lymphoblastic leukemia patients
Goroshchuk O; Vidarsdottir L; Bjorklund A-C; Hamil AS; Kolosenko I; Dowdy SF; Palm-Apergi C
Article: CELL DEATH & DISEASE. 2018;9(9):846
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment
Dyczynski M; Vesterlund M; Bjorklund A-C; Zachariadis V; Janssen J; Gallart-Ayala H; Daskalaki E; Wheelock CE; Lehtio J; Grander D; Tamm KP; Nilsson R
Article: EJNMMI RESEARCH. 2018;8(1):27
Hallmarks in prostate cancer imaging with Ga68-PSMA-11-PET/CT with reference to detection limits and quantitative properties
Sanchez-Crespo A; Jussing E; Bjorklund A-C; Tamm KP
Article: JOURNAL OF CONTROLLED RELEASE. 2017;261:199-206
RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients
Kolosenko I; Edsbacker E; Bjorklund A-C; Hamil AS; Goroshchuk O; Grander D; Dowdy SF; Palm-Apergi C
Article: ONCOTARGET. 2015;6(35):37066-37082
Sorafenib-induced defective autophagy promotes cell death by necroptosis
Kharaziha P; Chioureas D; Baltatzis G; Fonseca P; Rodriguez P; Gogvadze V; Lennartsson L; Bjorklund A-C; Zhivotovsky B; Grander D; Egevad L; Nilsson S; Panaretakis T
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(5):600-611
An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma
Lin H; Kolosenko I; Bjorklund A-C; Protsyuk D; Osterborg A; Grander D; Tamm KP
Article: CELL DEATH & DISEASE. 2012;3(1):e262
Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells
Kharaziha P; Rodriguez P; Li Q; Rundqvist H; Bjoerklund A-C; Augsten M; Ullen A; Egevad L; Wiklund P; Nilsson S; Kroemer G; Grander D; Panaretakis T
Article: BLOOD CANCER JOURNAL. 2011;1(7):e31
Glucocorticoid-induced cell death is mediated through reduced glucose metabolism in lymphoid leukemia cells
Buentke E; Nordstrom A; Lin H; Bjorklund A-C; Laane E; Harada M; Lu L; Tegnebratt T; Stone-Elander S; Heyman M; Soderhall S; Porwit A; Ostenson C-G; Shoshan M; Tamm KP; Grander D
Article: EXPERIMENTAL CELL RESEARCH. 2011;317(1):9-19
Activation of STAT1 is required for interferon-alpha-mediated cell death
Arulampalam V; Kolosenko I; Hjortsbert L; Bjorklund A-C; Grander D; Tamm KP
Article: CELL DEATH AND DIFFERENTIATION. 2009;16(7):1018-1029
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy
Laane E; Tamm KP; Buentke E; Ito K; Kharaziha P; Oscarsson J; Corcoran M; Bjorklund A-C; Hultenby K; Lundin J; Heyman M; Soderhall S; Mazur J; Porwit A; Pandolfi PP; Zhivotovsky B; Panaretakis T; Grander D
Article: EMBO JOURNAL. 2009;28(5):578-590
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
Panaretakis T; Kepp O; Brockmeier U; Tesniere A; Bjorklund A-C; Chapman DC; Durchschlag M; Joza N; Pierron G; van Endert P; Yuan J; Zitvogel L; Madeo F; Williams DB; Kroemer G
Article: MOLECULAR BIOLOGY OF THE CELL. 2008;19(1):41-50
Interferon α induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH₂-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin
Panaretakis T; Hjortsberg L; Tamm KP; Bjorklund A-C; Joseph B; Grander D
Article: MOLECULAR BIOLOGY OF THE CELL. 2005;16(8):3821-3831
Doxorubicin requires the sequential activation of caspase-2, protein kinase Cδ, and c-Jun NH₂-terminal kinase to induce apoptosis
Panaretakis T; Laane E; Pokrovskaja K; Björklund AC; Moustakas A; Zhivotovsky B; Heyman M; Shoshan MC; Grandér D
Article: INTERNATIONAL JOURNAL OF CANCER. 1996;67(1):106-112
Wild-type p53-induced apoptosis in a Burkitt lymphoma cell line is inhibited by interferon gamma
Sangfelt O; Einhorn S; Bjorklund AC; Wiman KG; Okan I; Grander D
Article: SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY. 1996;31(6):604-611
Factors influencing the response to interferon therapy in chronic hepatitis C - Studies on viral genotype and induction of 2',5'-oligoadenylate synthetase in the liver and peripheral blood cells
Grander D; Hultcrantz R; Weiland O; Xu B; Sangfelt O; Bjorklund AC; Befrits R; Bjorkholm M; Gruber A; Kinnman N; Reichard O; Widell A; Einhorn S

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