Andreas Hober

Andreas Hober

Postdoctoral Researcher
Visiting address: Entrévägen 2, 18257 Danderyd
Postal address: D1 Kliniska vetenskaper, Danderyds sjukhus, D1 Medicin Klinisk immunologi, 171 77 Stockholm
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About me

  • Andreas Hober received his PhD in Biotechnology from KTH Royal Institute of Technology in 2022 under the supervision of Prof. Mathias Uhlén. His doctoral research focused on developing affinity enrichment and targeted proteomics strategies for clinical applications, with particular emphasis on stable isotope-labeled recombinant protein fragments for absolute quantification using selected reaction monitoring. His work advanced robust quantitative workflows for plasma proteomics and contributed to improved analytical strategies in biomedical mass spectrometry.
    Dr. Hober has authored or co-authored 20 peer-reviewed journal publications, including work in Science, Analytical Chemistry, Nature Communications, and eLife. His research spans quantitative plasma proteomics, biomarker development, antibody validation, clinical mass spectrometry, and patient-centric sampling technologies. His first-author contributions include high-precision assays for apolipoprotein quantification, mass spectrometry-based detection of SARS-CoV-2, and analytical evaluations of decentralized sampling strategies for biomarker monitoring.
     
    Following his PhD, he conducted postdoctoral research at AstraZeneca within BioPharmaceuticals R&D, where he worked on patient-centric home sampling solutions for biomarker monitoring in clinical trials, evaluating microsampling devices using both mass spectrometry- and immunoassay-based strategies.
     
    In October 2024, Dr. Hober joined Karolinska Institutet as a postdoctoral researcher in the group of Charlotte Thålin. His current research focuses on mucosal immunology of the respiratory tract, integrating omics and immunological methodologies to investigate local antibody responses and epithelial immune mechanisms. His work includes the use of advanced sampling approaches and epithelial organoid models to study antibody dynamics, particularly IgA, with the aim of improving our understanding of protective mucosal immunity and its clinical implications.
     
    In recognition of the quality and impact of his doctoral work, Andreas received an honorary mention in the 2024 Phabian Award for best doctoral thesis in pharmaceutical and biomedical analysis, awarded annually by Apotekarsocieteten’s Section for Pharmaceutical and Biomedical Analysis.
     
    Beyond his scientific contributions, Andreas is actively engaged in strengthening the proteomics community. He serves as President of Swedish Proteomics Early Career Scientists (SPECS), is a Board Member of the Swedish Proteomics Society, and has held leadership roles within the HUPO Early Career Researcher Initiative, fostering national and international collaboration among early-career researchers in proteomics.

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Employments

  • Postdoctoral Researcher, Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 2025-2026
  • Postdoctoral Fellow, Department of Translational Science and Experimental Medicine, AstraZeneca R&D Gothenburg, 2023-2025
  • Researcher, Department of Protein Science, KTH Royal Institute of Technology, 2022-2023
  • PhD Student, Department of Protein Science, KTH Royal Institute of Technology, 2018-2022
  • Research Engineer, Department of Protein Science, KTH Royal Institute of Technology, 2017-2018

Degrees and Education

  • Doctor of Philosophy, Biotechnology, Development of novel affinity enrichment strategies for clinical applications using selected reaction monitoring, Department of Protein Science, KTH Royal Institute of Technology, 2022
  • Master of Science in Engineering, Biotechnology, Sample Normalization of Dried Blood Spots: Accurate Diagnostics Using Targeted Proteomics, Department of Protein Science, KTH Royal Institute of Technology, 2017
  • Master of Science, Biotechnology, Sample Normalization of Dried Blood Spots: Accurate Diagnostics Using Targeted Proteomics, Department of Protein Science, KTH Royal Institute of Technology, 2017
  • Bachelor of Science, Biotechnology, Towards an organic tolerable protease for transacylation application, KTH Royal Institute of Technology, 2015

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