Anders Hamsten

About me
Publications
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About me

Led own research group since 1987. The appointment was financed by the Medical Research Council until 1990, and from 1991 to 1997 by the Swedish Heart and Lung Foundation.

Docent (associate professor) in 1990 and professor in 1999.

Between 1993 and 2007, director of the King Gustaf V Research Institute, and between 1999 and 2007 the head of KI's Department of Medicine in Solna. From 2007 to 2012 head of division at the same department.

Alongside my research, I have also worked as a clinician. Received specialist training in heart disease and internal medicine at Danderyd Hospital from 1982 to 1986. Between 1987 and 2012 I worked as a cardiologist at Karolinska University Hospital, where I was consultant from 1997. From 2004 to 2007 I was head of the Thorax division.

Became a member of the Nobel Assembly at KI in 2004. Positions of trust for several bodies, including the King Gustav V 80th Birthday Fund, the Salus Ansvar Foundation, the Ragnar Söderberg Foundation and the Research Council of the Swedish Heart and Lung Foundation.

Education:
• Degree in medicine from Karolinska Institutet (KI) in 1978.
• PhD with his thesis on "Studies on myocardial infarction at young age" in 1986.
• Specialist training in heart disease and internal medicine at Danderyd Hospital from 1982 to 1986.
• Docent (associate professor) in 1990 and professor in 1999.

Academic honours, awards and prizes:
Among others prize for best original article (1986) from the Scandinavian Society for Atherosclerosis Research, and the 1997 Friedrich Merz Prize from Frankfurt University.

Research

Researches into the aetiology and prevention of atherosclerosis in the coronary artery (CAD). The causes of CAD are complex and involve numerous physiological systems, such as blood lipid metabolism, immunological defence and blood coagulation. In order to explain the high degree of CAD hereditariness in certain families, the existence has been posited of relatively rare gene variants with a much greater impact on disease risk than other involved genes. The search for such high-risk genes is a pursuit of particular interest to my research group.

One protein that I've been researching into for the past few decades is plasminogen activator inhibitor-1 (PAI-1), which plays a key part in the fibrinolytic (clot breakdown) system. As a doctoral student I helped to make the first discoveries on the links between PAI-1 and CAD, and since then the protein has become a recurrent theme in my research. For example, I was the first scientist in the world to show that high concentrations of PAI-1 in the blood increase the risk of cardiac infarction.

In recent years, I have spent much of my time working with major international partners on the identification of the genes and biological mechanisms of coronary artery disease (CAD). For instance, until 2012 I led PROCARDIS, a consortium comprising eight research centres in Sweden, Britain, Italy, Germany, France and Spain. As a result of these international collaborations, I spent 20 per cent of my working year at the Wellcome Trust Centre for Human Genetics at the University of Oxford between 2007 and 2012.

Alongside my research, I've worked as a cardiologist at Karolinska University Hospital from 1987 to 2012.

Articles

Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1151-1161
Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function
Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Ottosson V; Forsberg D; Thorlacius GE; Biavati L; Strandberg L; Mofors J; Ramskold D; Ruhrmann S; Meneghel L; Nyberg W; Espinosa A; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2021;19(8):2019-2028
FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer
Thibord F; Song C; Pattee J; Rodriguez BAT; Chen M-H; O'Donnell CJ; Kleber ME; Delgado GE; Guo X; Yao J; Taylor KD; Ozel AB; Brody JA; McKnight B; Gyorgy B; Simonsick E; Leonard HL; Carrasquilla GD; Guindo-Martinez M; Silveira A; Temprano-Sagrera G; Yanek LR; Becker DM; Mathias RA; Becker LC; Raffield LM; Kilpelainen TO; Grarup N; Pedersen O; Hansen T; Linneberg A; Hamsten A; Watkins H; Sabater-Lleal M; Nalls MA; Tregouet D-A; Morange P-E; Psaty BM; Tracy RP; Smith NL; Desch KC; Cushman M; Rotter JI; de Vries PS; Pankratz ND; Folsom AR; Morrison AC; Maerz W; Tang W; Johnson AD
Article: NATURE GENETICS. 2021;53(6):840-860
The trans-ancestral genomic architecture of glycemic traits
Chen J; Spracklen CN; Marenne G; Varshney A; Corbin LJ; Luan J; Willems SM; Wu Y; Zhang X; Horikoshi M; Boutin TS; Magi R; Waage J; Li-Gao R; Chan KHK; Yao J; Anasanti MD; Chu AY; Claringbould A; Heikkinen J; Hong J; Hottenga J-J; Huo S; Kaakinen MA; Louie T; Maerz W; Moreno-Macias H; Ndungu A; Nelson SC; Nolte IM; North KE; Raulerson CK; Ray D; Rohde R; Rybin D; Schurmann C; Sim X; Southam L; Stewart ID; Wang CA; Wang Y; Wu P; Zhang W; Ahluwalia TS; Appel EVR; Bielak LF; Brody JA; Burtt NP; Cabrera CP; Cade BE; Chai JF; Chai X; Chang L-C; Chen C-H; Chen BH; Chitrala KN; Chiu Y-F; de Haan HG; Delgado GE; Demirkan A; Duan Q; Engmann J; Fatumo SA; Gayan J; Giulianini F; Gong JH; Gustafsson S; Hai Y; Hartwig FP; He J; Heianza Y; Huang T; Huerta-Chagoya A; Hwang MY; Jensen RA; Kawaguchi T; Kentistou KA; Kim YJ; Kleber ME; Kooner IK; Lai S; Lange LA; Langefeld CD; Lauzon M; Li M; Ligthart S; Liu J; Loh M; Long J; Lyssenko V; Mangino M; Marzi C; Montasser ME; Nag A; Nakatochi M; Noce D; Noordam R; Pistis G; Preuss M; Raffield L; Rasmussen-Torvik LJ; Rich SS; Robertson NR; Rueedi R; Ryan K; Sanna S; Saxena R; Schraut KE; Sennblad B; Setoh K; Smith AV; Sparso T; Strawbridge RJ; Takeuchi F; Tan J; Trompet S; van den Akker E; van der Most PJ; Verweij N; Vogel M; Wang H; Wang C; Wang N; Warren HR; Wen W; Wilsgaard T; Wong A; Wood AR; Xie T; Zafarmand MH; Zhao J-H; Zhao W; Amin N; Arzumanyan Z; Astrup A; Bakker SJL; Baldassarre D; Beekman M; Bergman RN; Bertoni A; Blueher M; Bonnycastle LL; Bornstein SR; Bowden DW; Cai Q; Campbell A; Campbell H; Chang YC; de Geus EJC; Dehghan A; Du S; Eiriksdottir G; Farmaki AE; Franberg M; Fuchsberger C; Gao Y; Gjesing AP; Goel A; Han S; Hartman CA; Herder C; Hicks AA; Hsieh C-H; Hsueh WA; Ichihara S; Igase M; Ikram MA; Johnson WC; Jorgensen ME; Joshi PK; Kalyani RR; Kandeel FR; Katsuya T; Khor CC; Kiess W; Kolcic I; Kuulasmaa T; Kuusisto J; Lall K; Lam K; Lawlor DA; Lee NR; Lemaitre RN; Li H; Lin S-Y; Lindstrom J; Linneberg A; Liu J; Lorenzo C; Matsubara T; Matsuda F; Mingrone G; Mooijaart S; Moon S; Nabika T; Nadkarni GN; Nadler JL; Nelis M; Neville MJ; Norris JM; Ohyagi Y; Peters A; Peyser PA; Polasek O; Qi Q; Raven D; Reilly DF; Reiner A; Rivideneira F; Roll K; Rudan I; Sabanayagam C; Sandow K; Sattar N; Schuermann A; Shi J; Stringham HM; Taylor KD; Teslovich TM; Thuesen B; Timmers PRHJ; Tremoli E; Tsai MY; Uitterlinden A; van Dam RM; van Heemst D; van Hylckama Vlieg A; van Vliet-Ostaptchouk JV; Vangipurapu J; Vestergaard H; Wang T; Willems van Dijk K; Zemunik T; Abecasis GR; Adair LS; Aguilar-Salinas CA; Alarcon-Riquelme ME; An P; Aviles-Santa L; Becker DM; Beilin LJ; Bergmann S; Bisgaard H; Black C; Boehnke M; Boerwinkle E; Boehm BO; Bonnelykke K; Boomsma DI; Bottinger EP; Buchanan TA; Canouil M; Caulfield MJ; Chambers JC; Chasman DI; Chen Y-DI; Cheng C-Y; Collins FS; Correa A; Cucca F; de Silva HJ; Dedoussis G; Elmstahl S; Evans MK; Ferrannini E; Ferrucci L; Florez JC; Franks PW; Frayling TM; Froguel P; Gigante B; Goodarzi MO; Gordon-Larsen P; Grallert H; Grarup N; Grimsgaard S; Groop L; Gudnason V; Guo X; Hamsten A; Hansen T; Hayward C; Heckbert SR; Horta BL; Huang W; Ingelsson E; James PS; Jarvelin M-R; Jonas JB; Jukema JW; Kaleebu P; Kaplan R; Kardia SLR; Kato N; Keinanen-Kiukaanniemi SM; Kim B-J; Kivimaki M; Koistinen HA; Kooner JS; Koerner A; Kovacs P; Kuh D; Kumari M; Kutalik Z; Laakso M; Lakka TA; Launer LJ; Leander K; Li H; Lin X; Lind L; Lindgren C; Liu S; Loos RJF; Magnusson PKE; Mahajan A; Metspalu A; Mook-Kanamori DO; Mori TA; Munroe PB; Njolstad I; O'Connell JR; Oldehinkel AJ; Ong KK; Padmanabhan S; Palmer CNA; Palmer ND; Pedersen O; Pennell CE; Porteous DJ; Pramstaller PP; Province MA; Psaty BM; Qi L; Raffel LJ; Rauramaa R; Redline S; Ridker PM; Rosendaal FR; Saaristo TE; Sandhu M; Saramies J; Schneiderman N; Schwarz P; Scott LJ; Selvin E; Sever P; Shu X-O; Slagboom PE; Small KS; Smith BH; Snieder H; Sofer T; Sorensen TIA; Spector TD; Stanton A; Steves CJ; Stumvoll M; Sun L; Tabara Y; Tai ES; Timpson NJ; Tonjes A; Tuomilehto J; Tusie T; Uusitupa M; van der Harst P; van Duijn C; Vitart V; Vollenweider P; Vrijkotte TGM; Wagenknecht LE; Walker M; Wang YX; Wareham NJ; Watanabe RM; Watkins H; Wei WB; Wickremasinghe AR; Willemsen G; Wilson JF; Wong T-Y; Wu J-Y; Xiang AH; Yanek LR; Yengo L; Yokota M; Zeggini E; Zheng W; Zonderman AB; Rotter JI; Gloyn AL; McCarthy MI; Dupuis J; Meigs JB; Scott RA; Prokopenko I; Leong A; Liu C-T; Parker SCJ; Mohlke KL; Langenberg C; Wheeler E; Morris AP; Barroso I
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2021;41(5):1777-1788
Plasma Protein Profile of Carotid Artery Atherosclerosis and Atherosclerotic Outcomes Meta-Analyses and Mendelian Randomization Analyses
Lind L; Gigante B; Borne Y; Feldreich T; Leppert J; Hedberg P; Ostgren CJ; Nystrom FH; Sundstrom J; Arnlov J; Baldassarre D; Tremoli E; Veglia F; Hamsten A; O'Donnell CJ; Franceschini N; Orho-Melander M; Nilsson J; Melander O; Engstrom G; Malarstig A
Article: HUMAN MOLECULAR GENETICS. 2021;30(5):393-409
Genome-wide association study of circulating interleukin 6 levels identifies novel loci
Ahluwalia TS; Prins BP; Abdollahi M; Armstrong NJ; Aslibekyan S; Bain L; Jefferis B; Baumert J; Beekman M; Ben-Shlomo Y; Bis JC; Mitchell BD; de Geus E; Delgado GE; Marek D; Eriksson J; Kajantie E; Kanoni S; Kemp JP; Lu C; Marioni RE; McLachlan S; Milaneschi Y; Nolte IM; Petrelis AM; Porcu E; Sabater-Lleal M; Naderi E; Seppala I; Shah T; Singhal G; Standl M; Teumer A; Thalamuthu A; Thiering E; Trompet S; Ballantyne CM; Benjamin EJ; Casas JP; Toben C; Dedoussis G; Deelen J; Durda P; Engmann J; Feitosa MF; Grallert H; Hammarstedt A; Harris SE; Homuth G; Hottenga J-J; Jalkanen S; Jamshidi Y; Jawahar MC; Jess T; Kivimaki M; Kleber ME; Lahti J; Liu Y; Marques-Vidal P; Mellstrom D; Mooijaart SP; Muller-Nurasyid M; Penninx B; Revez JA; Rossing P; Raikkonen K; Sattar N; Scharnagl H; Sennblad B; Silveira A; St Pourcain B; Timpson NJ; Trollor J; van Dongen J; Van Heemst D; Visvikis-Siest S; Vollenweider P; Volker U; Waldenberger M; Willemsen G; Zabaneh D; Morris RW; Arnett DK; Baune BT; Boomsma DI; Chang Y-PC; Deary IJ; Deloukas P; Eriksson JG; Evans DM; Ferreira MA; Gaunt T; Gudnason V; Hamsten A; Heinrich J; Hingorani A; Humphries SE; Jukema JW; Koenig W; Kumari M; Kutalik Z; Lawlor DA; Lehtimaki T; Marz W; Mather KA; Naitza S; Nauck M; Ohlsson C; Price JF; Raitakari O; Rice K; Sachdev PS; Slagboom E; Sorensen TIA; Spector T; Stacey D; Stathopoulou MG; Tanaka T; Wannamethee SG; Whincup P; Rotter JI; Dehghan A; Boerwinkle E; Psaty BM; Snieder H; Alizadeh BZ
Article: SCIENTIFIC REPORTS. 2021;11(1):7866
Intake of food rich in saturated fat in relation to subclinical atherosclerosis and potential modulating effects from single genetic variants
Laguzzi F; Maitusong B; Strawbridge RJ; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; Kurl S; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Gigante B; Leander K
Article: EUROPEAN JOURNAL OF NUTRITION. 2021;60(1):123-134
Alcohol consumption in relation to carotid subclinical atherosclerosis and its progression: results from a European longitudinal multicentre study
Laguzzi F; Baldassarre D; Veglia F; Strawbridge RJ; Humphries SE; Rauramaa R; Smit AJ; Giral P; Silveira A; Tremoli E; Hamsten A; de Faire U; Frumento P; Leander K
Article: SCIENTIFIC REPORTS. 2021;11(1):632
The overlap of genetic susceptibility to schizophrenia and cardiometabolic disease can be used to identify metabolically different groups of individuals
Strawbridge RJ; Johnston KJA; Bailey MES; Baldassarre D; Cullen B; Eriksson P; deFaire U; Ferguson A; Gigante B; Giral P; Graham N; Hamsten A; Humphries SE; Kurl S; Lyall DM; Lyall LM; Pell JP; Pirro M; Savonen K; Smit AJ; Tremoli E; Tomainen T-P; Veglia F; Ward J; Sennblad B; Smith DJ
Article: NATURE COMMUNICATIONS. 2021;12(1):24
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability
Lagou V; Maegi R; Hottenga J-J; Grallert H; Perry JRB; Bouatia-Naji N; Marullo L; Rybin D; Jansen R; Min JL; Dimas AS; Ulrich A; Zudina L; Gadin JR; Jiang L; Faggian A; Bonnefond A; Fadista J; Stathopoulou MG; Isaacs A; Willems SM; Navarro P; Tanaka T; Jackson AU; Montasser ME; O'Connell JR; Bielak LF; Webster RJ; Saxena R; Stafford JM; Pourcain BS; Timpson NJ; Salo P; Shin S-Y; Amin N; Smith AV; Li G; Verweij N; Goel A; Ford I; Johnson PCD; Johnson T; Kapur K; Thorleifsson G; Strawbridge RJ; Rasmussen-Torvik LJ; Esko T; Mihailov E; Fall T; Fraser RM; Mahajan A; Kanoni S; Giedraitis V; Kleber ME; Silbernagel G; Meyer J; Mueller-Nurasyid M; Ganna A; Sarin A-P; Yengo L; Shungin D; Luan J; Horikoshi M; An P; Sanna S; Boettcher Y; Rayner NW; Nolte IM; Zemunik T; Iperen EV; Kovacs P; Hastie ND; Wild SH; McLachlan S; Campbell S; Polasek O; Carlson O; Egan J; Kiess W; Willemsen G; Kuusisto J; Laakso M; Dimitriou M; Hicks AA; Rauramaa R; Bandinelli S; Thorand B; Liu Y; Miljkovic I; Lind L; Doney A; Perola M; Hingorani A; Kivimaki M; Kumari M; Bennett AJ; Groves CJ; Herder C; Koistinen HA; Kinnunen L; Faire UD; Bakker SJL; Uusitupa M; Palmer CNA; Jukema JW; Sattar N; Pouta A; Snieder H; Boerwinkle E; Pankow JS; Magnusson PK; Krus U; Scapoli C; de Geus EJCN; Blueher M; Wolffenbuttel BHR; Province MA; Abecasis GR; Meigs JB; Hovingh GK; Lindstroem J; Wilson JF; Wright AF; Dedoussis GV; Bornstein SR; Schwarz PEH; Toenjes A; Winkelmann BR; Boehm BO; Maerz W; Metspalu A; Price JF; Deloukas P; Koerner A; Lakka TA; Keinanen-Kiukaanniemi SM; Saaristo TE; Bergman RN; Tuomilehto J; Wareham NJ; Langenberg C; Maennistoe S; Franks PW; Hayward C; Vitart V; Kaprio J; Visvikis-Siest S; Balkau B; Altshuler D; Rudan I; Stumvoll M; Campbell H; van Duijn CM; Gieger C; Illig T; Ferrucci L; Pedersen NL; Pramstaller PP; Boehnke M; Frayling TM; Shuldiner AR; Peyser PA; Kardia SLR; Palmer LJ; Penninx BW; Meneton P; Harris TB; Navis G; Harst PVD; Smith GD; Forouhi NG; Loos RJF; Salomaa V; Soranzo N; Boomsma DI; Groop L; Tuomi T; Hofman A; Munroe PB; Gudnason V; Siscovick DS; Watkins H; Lecoeur C; Vollenweider P; Franco-Cereceda A; Eriksson P; Jarvelin M-R; Stefansson K; Hamsten A; Nicholson G; Karpe F; Dermitzakis ET; Lindgren CM; McCarthy MI; Froguel P; Kaakinen MA; Lyssenko V; Watanabe RM; Ingelsson E; Florez JC; Dupuis J; Barroso I; Morris AP; Prokopenko I
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2020;13(6):e002769-648
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus
van Zuydam NR; Ladenvall C; Voight BF; Strawbridge RJ; Fernandez-Tajes J; Rayner NW; Robertson NR; Mahajan A; Vlachopoulou E; Goel A; Kleber ME; Nelson CP; Kwee LC; Esko T; Mihailov E; Magi R; Milani L; Fischer K; Kanoni S; Kumar J; Song C; Hartiala JA; Pedersen NL; Perola M; Gieger C; Peters A; Qu L; Willems SM; Doney ASF; Morris AD; Zheng Y; Sesti G; Hu FB; Qi L; Laakso M; Thorsteinsdottir U; Grallert H; van Duijn C; Reilly MP; Ingelsson E; Deloukas P; Kathiresan S; Metspalu A; Shah SH; Sinisalo J; Salomaa V; Hamsten A; Samani NJ; Maerz W; Hazen SL; Watkins H; Saleheen D; Morris AP; Colhoun HM; Groop L; McCarthy MI; Palmer CNA
Article: NATURE METABOLISM. 2020;2(10):1135-1148
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Folkersen L; Gustafsson S; Wang Q; Hansen DH; Hedman AK; Schork A; Page K; Zhernakova DV; Wu Y; Peters J; Eriksson N; Bergen SE; Boutin TS; Bretherick AD; Enroth S; Kalnapenkis A; Gadin JR; Suur BE; Chen Y; Matic L; Gale JD; Lee J; Zhang W; Quazi A; Ala-Korpela M; Choi SH; Claringbould A; Danesh J; Smith GD; de Masi F; Elmstahl S; Engstrom G; Fauman E; Fernandez C; Franke L; Franks PW; Giedraitis V; Haley C; Hamsten A; Ingason A; Johansson A; Joshi PK; Lind L; Lindgren CM; Lubitz S; Palmer T; Macdonald-Dunlop E; Magnusson M; Melander O; Michaelsson K; Morris AP; Magi R; Nagle MW; Nilsson PM; Nilsson J; Orho-Melander M; Polasek O; Prins B; Palsson E; Qi T; Sjogren M; Sundstrom J; Surendran P; Vosa U; Werge T; Wernersson R; Westra H-J; Yang J; Zhernakova A; Arnlov J; Fu J; Smith JG; Esko T; Hayward C; Gyllensten U; Landen M; Siegbahn A; Wilson JF; Wallentin L; Butterworth AS; Holmes MV; Ingelsson E; Malarstig A
Article: LIFE SCIENCE ALLIANCE. 2020;3(10):e202000817
Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality
Hong M-G; Dodig-Crnkovic T; Chen X; Drobin K; Lee W; Wang Y; Edfors F; Kotol D; Thomas CE; Sjoberg R; Odeberg J; Hamsten A; Silveira A; Hall P; Nilsson P; Pawitan Y; Uhlen M; Pedersen NL; Hagg S; Magnusson PK; Schwenk JM
Article: CIRCULATION RESEARCH. 2020;126(5):571-585
PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling
Rykaczewska U; Suur BE; Rohl S; Razuvaev A; Lengquist M; Sabater-Lleal M; van der Laan SW; Miller CL; Wirka RC; Kronqvist M; Diez MG; Vesterlund M; Gillgren P; Odeberg J; Lindeman JH; Veglia F; Humphries SE; de Faire U; Baldassarre D; Tremoli E; Lehtio J; Hansson GK; Paulsson-Berne G; Pasterkamp G; Quertermous T; Hamsten A; Eriksson P; Hedin U; Matic L
Article: ATHEROSCLEROSIS. 2020;295:25-30
The plasma protein profile and cardiovascular risk differ between intima-media thickness of the common carotid artery and the bulb: A meta-analysis and a longitudinal evaluation
Lind L; Gigante B; Borne Y; Malarstig A; Sundstrom J; Arnlov J; Ingelsson E; Baldassarre D; Tremoli E; Veglia F; Hamsten A; Orho-Melander M; Nilsson J; Melander O; Engstrom G
Article: GENES AND IMMUNITY. 2020;21(2):100-108
Analysis of the genetic variants associated with circulating levels of sgp130. Results from the IMPROVE study
Bonomi A; Veglia F; Baldassarre D; Strawbridge RJ; Golabkesh Z; Sennblad B; Leander K; Smit AJ; Giral P; Humphries SE; Tremoli E; Hamsten A; de Faire U; Gigante B; Sirtori CR; Castelnuovo S; Calabresi L; Amato M; Frigerio B; Ravani A; Sansaro D; Coggi D; Tedesco CC; Eriksson P; Silveira A; Laguzzi F; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; Rauramaa R; Van Gessel AI; Van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Kurl S; Vaudo G; Alaeddin A; Siepi D; Lupattelli G; Mannarino E
Article: JVS - VASCULAR SCIENCE. 2020;1:13-27
Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.
Röhl S; Rykaczewska U; Seime T; Suur BE; Diez MG; Gådin JR; Gainullina A; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JHN; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Matic LP
Article: JOURNAL OF INTERNAL MEDICINE. 2019;286(6):660-675
Subclinical atherosclerosis and its progression are modulated by PLIN2 through a feed-forward loop between LXR and autophagy
Saliba-Gustafsson P; Pedrelli M; Gertow K; Werngren O; Janas V; Pourteymour S; Baldassarre D; Tremoli E; Veglia F; Rauramaa R; Smit AJ; Giral P; Kurl S; Pirro M; de Faire U; Humphries SE; Hamsten A; Goncalves I; Orho-Melander M; Franco-Cereceda A; Boren J; Eriksson P; Magne J; Parini P; Ehrenborg E; Sirtori CR; Castelnuovo S; Amato M; Frigerio B; Ravani A; Sansaro D; Tedesco C; Bovis F; Discacciati A; Ahl M; Blomgren G; Eriksson MJ; Fahlstadius P; Heinonen M; Nilson L; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; van Gessel AI; van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Vaudo G; Alaeddin A; Siepi D; Lupattelli G; Schillaci G
Article: NATURE COMMUNICATIONS. 2019;10(1):4957
Associations of autozygosity with a broad range of human phenotypes
Clark DW; Okada Y; Moore KHS; Mason D; Pirastu N; Gandin I; Mattsson H; Barnes CLK; Lin K; Zhao JH; Deelen P; Rohde R; Schurmann C; Guo X; Giulianini F; Zhang W; Medina-Gomez C; Karlsson R; Bao Y; Bartz TM; Baumbach C; Biino G; Bixley MJ; Brumat M; Chai J-F; Corre T; Cousminer DL; Dekker AM; Eccles DA; Van Eijk KR; Fuchsberger C; Gao H; Germain M; Gordon SD; de Haan HG; Harris SE; Hofer E; Huerta-Chagoya A; Igartua C; Jansen IE; Jia Y; Kacprowski T; Karlsson T; Kleber ME; Li SA; Li-Gao R; Mahajan A; Matsuda K; Meidtner K; Meng W; Montasser ME; van der Most PJ; Munz M; Nutile T; Palviainen T; Prasad G; Prasad RB; Priyanka TDS; Rizzi F; Salvi E; Sapkota BR; Shriner D; Skotte L; Smart MC; Smith AV; van der Spek A; Spracklen CN; Strawbridge RJ; Tajuddin SM; Trompet S; Turman C; Verweij N; Viberti C; Wang L; Warren HR; Wootton RE; Yanek LR; Yao J; Yousri NA; Zhao W; Adeyemo AA; Afaq S; Alberto Aguilar-Salinas C; Akiyama M; Albert ML; Allison MA; Alver M; Aung T; Azizi F; Bentley AR; Boeing H; Boerwinkle E; Borja JB; de Borst GJ; Bottinger EP; Broer L; Campbell H; Chanock S; Chee M-L; Chen G; Chen Y-DI; Chen Z; Chiu Y-F; Cocca M; Collins FS; Concas MP; Corley J; Cugliari G; Van Dam RM; Damulina A; Daneshpour MS; Day FR; Delgado GE; Dhana K; Doney ASF; Doerr M; Doumatey AP; Dzimiri N; Ebenesersdottir SS; Elliott J; Elliott P; Ewert R; Felix JF; Fischer K; Freedman BI; Girotto G; Goel A; Gogele M; Goodarzi MO; Graff M; Granot-Hershkovitz E; Grodstein F; Guarrera S; Gudbjartsson DF; Guity K; Gunnarsson B; Guo Y; Hagenaars SP; Haiman CA; Halevy A; Harris TB; Hedayati M; van Heel DA; Hirata M; Hofer I; Hsiung CA; Huang J; Hung Y-J; Ikram MA; Jagadeesan A; Jousilahti P; Kamatani Y; Kanai M; Kerrison ND; Kessler T; Khaw K-T; Khor CC; de Kleijn DPV; Koh W-P; Kolcic I; Kraft P; Kramer BK; Kutalik Z; Kuusisto J; Langenberg C; Launer LJ; Lawlor DA; Lee I-T; Lee W-J; Lerch MM; Li L; Liu J; Loh M; London SJ; Loomis S; Lu Y; Luan J; Magi R; Manichaikul AW; Manunta P; Masson G; Matoba N; Mei XW; Meisinger C; Meitinger T; Mezzavilla M; Milani L; Millwood IY; Momozawa Y; Moore A; Morange P-E; Moreno-Macias H; Mori TA; Morrison AC; Muka T; Murakami Y; Murray AD; de Mutsert R; Mychaleckyj JC; Nalls MA; Nauck M; Neville MJ; Nolte IM; Ong KK; Orozco L; Padmanabhan S; Palsson G; Pankow JS; Pattaro C; Pattie A; Polasek O; Poulter N; Pramstaller PP; Quintana-Murci L; Raikkonen K; Ralhan S; Rao DC; van Rheenen W; Rich SS; Ridker PM; Rietveld CA; Robino A; van Rooij FJA; Ruggiero D; Saba Y; Sabanayagam C; Sabater-Lleal M; Felicita Sala C; Salomaa V; Sandow K; Schmidt H; Scott LJ; Scott WR; Sedaghati-Khayat B; Sennblad B; van Setten J; Sever PJ; Sheu WH-H; Shi Y; Shrestha S; Shukla SR; Sigurdsson JK; Sikka TT; Singh JR; Smith BH; Stancakova A; Stanton A; Starr JM; Stefansdottir L; Straker L; Sulem P; Sveinbjornsson G; Swertz MA; Taylor AM; Taylor KD; Terzikhan N; Tham Y-C; Thorleifsson G; Thorsteinsdottir U; Tillander A; Tracy RP; Tusie-Luna T; Tzoulaki I; Vaccargiu S; Vangipurapu J; Veldink JH; Vitart V; Volker U; Vuoksimaa E; Wakil SM; Waldenberger M; Wander GS; Wang YX; Wareham NJ; Wild S; Yajnik CS; Yuan J-M; Zeng L; Zhang L; Zhou J; Amin N; Asselbergs FW; Bakker SJL; Becker DM; Lehne B; Bennett DA; van den Berg LH; Berndt SI; Bharadwaj D; Bielak LF; Bochud M; Boehnke M; Bouchard C; Bradfield JP; Brody JA; Campbell A; Carmi S; Caulfield MJ; Cesarini D; Chambers JC; Chandak GR; Cheng C-Y; Ciullo M; Cornelis M; Cusi D; Smith GD; Deary IJ; Dorajoo R; van Duijn CM; Ellinghaus D; Erdmann J; Eriksson JG; Evangelou E; Evans MK; Faul JD; Feenstra B; Feitosa M; Foisy S; Franke A; Friedlander Y; Gasparini P; Gieger C; Gonzalez C; Goyette P; Grant SFA; Griffiths LR; Groop L; Gudnason V; Gyllensten U; Hakonarson H; Hamsten A; van der Harst P; Heng C-K; Hicks AA; Hochner H; Huikuri H; Hunt SC; Jaddoe VWV; De Jager PL; Johannesson M; Johansson A; Jonas JB; Jukema JW; Junttila J; Kaprio J; Kardia SLR; Karpe F; Kumari M; Laakso M; van der Laan SW; Lahti J; Laudes M; Lea RA; Lieb W; Lumley T; Martin NG; Marz W; Matullo G; McCarthy MI; Medland SE; Merriman TR; Metspalu A; Meyer BF; Mohlke KL; Montgomery GW; Mook-Kanamori D; Munroe PB; North KE; Nyholt DR; O'connell JR; Ober C; Oldehinkel AJ; Palmas W; Palmer C; Pasterkamp GG; Patin E; Pennell CE; Perusse L; Peyser PA; Pirastu M; Polderman TJC; Porteous DJ; Posthuma D; Psaty BM; Rioux JD; Rivadeneira F; Rotimi C; Rotter JI; Rudan I; Den Ruijter HM; Sanghera DK; Sattar N; Schmidt R; Schulze MB; Schunkert H; Scott RA; Shuldiner AR; Sim X; Small N; Smith JA; Sotoodehnia N; Tai E-S; Teumer A; Timpson NJ; Toniolo D; Tregouet D-A; Tuomi T; Vollenweider P; Wang CA; Weir DR; Whitfield JB; Wijmenga C; Wong T-Y; Wright J; Yang J; Yu L; Zemel BS; Zonderman AB; Perola M; Magnusson PKE; Uitterlinden AG; Kooner JS; Chasman DI; Loos RJF; Franceschini N; Franke L; Haley CS; Hayward C; Walters RG; Perry JRB; Esko T; Helgason A; Stefansson K; Joshi PK; Kubo M; Wilson JF
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(13):E3221-3221
Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes
Pujol-Moix N; Martinez-Perez A; Sabater-Lleal M; Llobet D; Vilalta N; Hamsten A; Carles Souto J; Manuel Soria J
Article: SCIENTIFIC REPORTS. 2019;9(1):7339
Genetic variation in CADM2 as a link between psychological traits and obesity
Morris J; Bailey MES; Baldassarre D; Cullen B; de Faire U; Ferguson A; Gigante B; Giral P; Goel A; Graham N; Hamsten A; Humphries SE; Johnston KJA; Lyall DM; Lyall LM; Sennblad B; Silveira A; Smit AJ; Tremoli E; Veglia F; Ward J; Watkins H; Smith DJ; Strawbridge RJ
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2019;282:88-92
A priori-defined Mediterranean-like dietary pattern predicts cardiovascular events better in north Europe than in Mediterranean countries
Veglia F; Baldassarre D; de Faire U; Kurl S; Smit AJ; Rauramaa R; Giral P; Amato M; Di Minno A; Ravani A; Frigerio B; Castelnuovo S; Sansaro D; Coggi D; Bonomi A; Tedesco CC; Mannarino E; Humphries SE; Hamsten A; Tremoli E; Calabresi L; Sirtori CR; Ahl M; Blomgren G; Eriksson MJ; Fahlstadius P; Heinonen M; Nilson L; Cooper J; Acharya J; Huttunen K; Rauramaa E; Pekkarinen H; Penttila IM; Torronen J; van Gessel AI; van Roon AM; Teune GC; Kuipers WD; Bruin M; Nicolai A; Haarsma-Jorritsma P; Mulder DJ; Bilo HJG; Smeets GH; Beaudeux JL; Kahn JF; Carreau V; Kontush A; Karppi J; Nurmi T; Nyyssonen K; Salonen R; Tuomainen TP; Tuomainen J; Kauhanen J; Vaudo G; Alaeddin A; Siepi D; Lupattelli G
Article: DATA IN BRIEF. 2019;23:103789
Data on the association between a simplified Mediterranean diet score and the incidence of combined, cardio and cerebro vascular events
Veglia F; Baldassarre D; de Faire U; Kurl S; Smit AJ; Rauramaa R; Giral P; Amato M; Di Minno A; Ravani A; Frigerio B; Castelnuovo S; Sansaro D; Coggi D; Bonomi A; Tedesco CC; Mannarino E; Humphries SE; Hamsten A; Tremoli E
Article: BLOOD. 2019;133(9):967-977
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology
de Vries PS; Sabater-Lleal M; Huffman JE; Marten J; Song C; Pankratz N; Bartz TM; de Haan HG; Delgado GE; Eicher JD; Martinez-Perez A; Ward-Caviness CK; Brody JA; Chen M-H; de Maat MPM; Franberg M; Gill D; Kleber ME; Rivadeneira F; Manuel Soria J; Tang W; Tofler GH; Uitterlinden AG; Vlieg AVH; Seshadri S; Boerwinkle E; Davies NM; Giese A-K; Ikram MK; Kittner SJ; McKnight B; Psaty BM; Reiner AP; Sargurupremraj M; Taylor KD; Fornage M; Hamsten A; Maerz W; Rosendaal FR; Carlos Souto J; Dehghan A; Johnson AD; Morrison AC; O'Donnell CJ; Smith NL
Article: NATURE COMMUNICATIONS. 2018;9(1):5141
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes
Franceschini N; Giambartolomei C; de Vries PS; Finan C; Bis JC; Huntley RP; Lovering RC; Tajuddin SM; Winkler TW; Graff M; Kavousi M; Dale C; Smith AV; Hofer E; van Leeuwen EM; Nolte IM; Lu L; Scholz M; Sargurupremraj M; Pitkanen N; Franzen O; Joshi PK; Noordam R; Marioni RE; Hwang S-J; Musani SK; Schminke U; Palmas W; Isaacs A; Correa A; Zonderman AB; Hofman A; Teumer A; Cox AJ; Uitterlinden AG; Wong A; Smit AJ; Newman AB; Britton A; Ruusalepp A; Sennblad B; Hedblad B; Pasaniuc B; Penninx BW; Langefeld CD; Wassel CL; Tzourio C; Fava C; Baldassarre D; O'Leary DH; Teupser D; Kuh D; Tremoli E; Mannarino E; Grossi E; Boerwinkle E; Schadt EE; Ingelsson E; Veglia F; Rivadeneira F; Beutner F; Chauhan G; Heiss G; Snieder H; Campbell H; Voelzke H; Markus HS; Deary IJ; Jukema JW; de Graaf J; Price J; Pott J; Hopewell JC; Liang J; Thiery J; Engmann J; Gertow K; Rice K; Taylor KD; Dhana K; Kiemeney LALM; Lind L; Raffield LM; Launer LJ; Holdt LM; Doer M; Dichgans M; Traylor M; Sitzer M; Kumari M; Kivimaki M; Nalls MA; Melander O; Raitakari O; Franco OH; Rueda-Ochoa OL; Roussos P; Whincup PH; Amouyel P; Giral P; Anugu P; Wong Q; Malik R; Rauramaa R; Burkhardt R; Hardy R; Schmidt R; de Mutsert R; Morris RW; Strawbridge RJ; Wannamethee SG; Hagg S; Shah S; McLachlan S; Trompet S; Seshadri S; Kurl S; Heckbert SR; Ring S; Harris TB; Lehtimaki T; Galesloot TE; Shah T; de Faire U; Plagnol V; Rosamond WD; Post W; Zhu X; Zhang X; Guo X; Saba Y; Dehghan A; Seldenrijk A; Morrison AC; Hamsten A; Psaty BM; van Duijn CM; Lawlor DA; Mook-Kanamori DO; Bowden DW; Schmidt H; Wilson JF; Wilson JG; Rotter JI; Wardlaw JM; Deanfield J; Halcox J; Lyytikainen L-P; Loeffler M; Evans MK; Debette S; Humphries SE; Voelker U; Gudnason V; Hingorani AD; Bjorkegren JLM; Casas JP; O'Donnell CJ
Article: NEUROLOGY: GENETICS. 2018;4(6):e293
Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes
Pulit SL; Weng L-C; McArdle PF; Trinquart L; Choi SH; Mitchell BD; Rosand J; de Bakker PIW; Benjamin EJ; Ellinor PT; Kittner SJ; Lubitz SA; Anderson CD; Christophersen IE; Rienstra M; Roselli C; Yin X; Geelhoed B; Barnard J; Lin H; Arking DE; Smith AV; Albert CM; Chaffin M; Tucker NR; Li M; Klarin D; Bihlmeyer NA; Low S-K; Weeke PE; Mueller-Nurasyid M; Smith JG; Brody JA; Niemeijer MN; Doerr M; Trompet S; Huffman J; Gustafsson S; Schurmann C; Kleber ME; Lyytikainen L-P; Seppala I; Malik R; Horimoto ARVR; Perez M; Sinisalo J; Aeschbacher S; Theriault S; Yao J; Radmanesh F; Weiss S; Teumer A; Clauss S; Deo R; Rader DJ; Shah S; Sun A; Hopewell JC; Debette S; Chauhan G; Yang Q; Worrall BB; Pare G; Kamatani Y; Hagemeijer YP; Verweij N; Siland JE; Kubo M; Smith JD; Van Wagoner DR; Bis JC; Perz S; Psaty BM; Ridker PM; Magnani JW; Harris TB; Launer LJ; Shoemaker MB; Padmanabhan S; Haessler J; Bartz TM; Waldenberger M; Lichtner P; Arendt M; Krieger JE; Kahonen M; Risch L; Mansur AJ; Peters A; Smith BH; Lind L; Scott SA; Lu Y; Bottinger EB; Hernesniemi J; Lindgren CM; Wong JA; Huang J; Eskola M; Morris AP; Ford I; Reiner AP; Delgado G; Chen LY; Chen Y-DI; Sandhu RK; Li M; Boerwinkle E; Eisele L; Lannfelt L; Rost N; Taylor KD; Campbell A; Magnusson PK; Porteous D; Hocking LJ; Vlachopoulou E; Pedersen NL; Nikus K; Orho-Melander M; Hamsten A; Heeringa J; Denny JC; Kriebel J; Darbar D; Newton-Cheh C; Shaffer C; Macfarlane PW; Heilmann S; Almgren P; Huang PL; Sotoodehnia N; Soliman EZ; Uitterlinden AG; Hofman A; Franco OH; Voelker U; Joeckel K-H; Sinner MF; Lin HJ; Guo X; Dichgans M; Ingelsson E; Kooperberg C; Melander O; Loos RJF; Laurikka J; Conen D; van der Harst P; Lokki M-L; Kathiresan S; Pereira A; Jukema JW; Hayward C; Rotter JI; Maerz W; Lehtimaki T; Stricker BH; Chung MK; Felix SB; Gudnason V; Alonso A; Roden DM; Kaeaeb S; Chasman DI; Heckbert SR; Tanaka T; Lunetta KL; Smoller S; Sorkin J; Wang X; Selim M; Pikula A; Wolf P; Seshadri S; de Bakker P; Chasman D; Rexrode K; Chen I; Rotter J; Luke M; Sale M; Lee T-H; Chang K-C; Elkind M; Goldstein L; James ML; Breteler M; O'Donnell C; Leys D; Carty C; Kidwell C; Olesen J; Sharma P; Rich S; Tatlisumak T; Happola O; Bijlenga P; Soriano C; Giralt E; Roquer J; Jimenez-Conde J; Cotlarcius I; Hardy J; Korostynski M; Boncoraglio G; Ballabio E; Parati E; Mateusz A; Urbanik A; Dziedzic T; Jagiella J; Gasowski J; Wnuk M; Olszanecki R; Pera J; Slowik A; Juchniewicz KJ; Levi C; Nyquist P; Cendes I; Cabral N; Franca P; Goncalves A; Keller L; Crisby M; Kostulas K; Lemmens R; Ahmadi K; Opherk C; Duering M; Gonik M; Staals J; Burri P; Sadr-Nabavi A; Romero J; Biffi A; Anderson C; Falcone G; Brouwers B; Du R; Kourkoulis C; Battey T; Lubitz S; Mueller-Myhsok B; Meschia J; Brott T; Pichler A; Enzinger C; Schmidt H; Schmidt R; Seiler S; Blanton S; Yamada Y; Bersano A; Rundek T; Sacco R; Chan Y-FY; Gschwendtner A; Deng Z; Barr T; Gwinn K; Corriveau R; Singleton A; Waddy S; Launer L; Chen C; Le KE; Lee WL; Tan EK; Olugbodi A; Rothwell P; Schilling S; Mok V; Lebedeva E; Jern C; Jood K; Olsson S; Kim H; Lee C; Kilarski L; Markus H; Peycke J; Bevan S; Sheu W; Chiou HY; Chern J; Giraldo E; Taqi M; Jain V; Lam O; Howard G; Woo D; Kittner S; Mitchell B; Cole J; O'Connell J; Milewicz D; Illoh K; Worrall B; Stine C; Karaszewski B; Werring D; Sofat R; Smalley J; Lindgren A; Hansen B; Norrving B; Smith G; Jose Martin J; Thijs V; Klijn K; van't Hof F; Algra A; Macleod M; Perry R; Arnett D; Pezzini A; Padovani A; Cramer S; Fisher M; Saleheen D; Broderick J; Kissela B; Doney A; Sudlow C; Rannikmae K; Silliman S; McDonough C; Walters M; Pedersen A; Nakagawa K; Chang C; Dobbins M; McArdle P; Chang Y-C; Brown R; Brown D; Holliday E; Kalaria R; Maguire J; Attia J; Farrall M; Giese A-K; Fornage M; Majersik J; Cushman M; Keene K; Bennett S; Tirschwell D; Psaty B; Reiner A; Longstreth W; Spence D; Montaner J; Fernandez-Cadenas I; Langefeld C; Bushnell C; Heitsch L; Lee J-M; Sheth K
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2018;103(5):691-706
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
Ligthart S; Vaez A; Vosa U; Stathopoulou MG; de Vries PS; Prins BP; Van der Most PJ; Tanaka T; Naderi E; Rose LM; Wu Y; Karlsson R; Barbalic M; Lin H; Pool R; Zhu G; Mace A; Sidore C; Trompet S; Mangino M; Sabater-Lleal M; Kemp JP; Abbasi A; Kacprowski T; Verweij N; Smith AV; Huang T; Marzi C; Feitosa MF; Lohman KK; Kleber ME; Milaneschi Y; Mueller C; Huq M; Vlachopoulou E; Lyytikainen L-P; Oldmeadow C; Deelen J; Perola M; Zhao JH; Feenstra B; Amini M; Lahti J; Schraut KE; Fornage M; Suktitipat B; Chen W-M; Li X; Nutile T; Malerba G; Luan J; Bak T; Schork N; Del Greco FM; Thiering E; Mahajan A; Marioni RE; Mihailov E; Eriksson J; Ozel AB; Zhang W; Nethander M; Cheng Y-C; Aslibekyan S; Ang W; Gandin I; Yengo L; Portas L; Kooperberg C; Hofer E; Rajan KB; Schurmann C; den Hollander W; Ahluwalia TS; Zhao J; Draisma HHM; Ford I; Timpson N; Teumer A; Huang H; Wahl S; Liu Y; Huang J; Uh H-W; Geller F; Joshi PK; Yanek LR; Trabetti E; Lehne B; Vozzi D; Verbanck M; Biino G; Saba Y; Meulenbelt I; O'Connell JR; Laakso M; Giulianini F; Magnusson PKE; Ballantyne CM; Hottenga JJ; Montgomery G; Rivadineira F; Rueedi R; Steri M; Herzig K-H; Stott DJ; Menni C; Franberg M; St Pourcain B; Felix SB; Pers TH; Bakker SJL; Kraft P; Peters A; Vaidya D; Delgado G; Smit JH; Grossmann V; Sinisalo J; Seppala I; Williams SR; Holliday EG; Moed M; Langenberg C; Raikkonen K; Ding J; Campbell H; Sale MM; Chen Y-DI; James AL; Ruggiero D; Soranzo N; Hartman CA; Smith EN; Berenson GS; Fuchsberger C; Hernandez D; Tiesler CMT; Giedraitis V; Liewald D; Fischer K; Mellstrom D; Larsson A; Wang Y; Scott WR; Lorentzon M; Beilby J; Ryan KA; Pennell CE; Vuckovic D; Balkau B; Concas MP; Schmidt R; de Leon CFM; Bottinger EP; Kloppenburg M; Paternoster L; Boehnke M; Musk AW; Willemsen G; Evans DM; Madden PAF; Kahonen M; Kutalik Z; Zoledziewska M; Karhunen V; Kritchevsky SB; Sattar N; Lachance G; Clarke R; Harris TB; Raitakari OT; Attia JR; Van Heemst D; Kajantie E; Sorice R; Gambaro G; Scott RA; Hicks AA; Ferrucci L; Standl M; Lindgren CM; Starr JM; Karlsson M; Lind L; Li JZ; Chambers JC; Mori TA; de Geus EJCN; Heath AC; Martin NG; Auvinen J; Buckley BM; de Craen AJM; Waldenberger M; Strauch K; Meitinger T; Scott RJ; McEvoy M; Beekman M; Bombieri C; Ridker PM; Mohlke KL; Pedersen NL; Morrison AC; Boomsma DI; Whitfield JB; Strachan DP; Hofman A; Vollenweider P; Cucca F; Jarvelin M-R; Jukema JW; Spector TD; Hamsten A; Zeller T; Uitterlinden AG; Nauck M; Gudnason V; Qi L; Grallert H; Borecki IB; Rotter JI; Maerz W; Wild PS; Lokki M-L; Boyle M; Salomaa V; Melbye M; Eriksson JG; Wilson JF; Penninx BWJH; Becker DM; Worrall BB; Gibson G; Krauss RM; Ciullo M; Zaza G; Wareham NJ; Oldehinkel AJ; Palmer LJ; Murray SS; Pramstaller PP; Bandinelli S; Heinrich J; Ingelsson E; Deary IJ; Magi R; Vandenput L; van der Harst P; Desch KC; Kooner JS; Ohlsson C; Hayward C; Lehtimaki T; Shuldiner AR; Arnett DK; Beilin LJ; Robino A; Froguel P; Pirastu M; Jess T; Koenig W; Loos RJF; Evans DA; Schmidt H; Smith GD; Slagboom PE; Eiriksdottir G; Morris AP; Psaty BM; Tracy RP; Nolte IM; Boerwinkle E; Visvikis-Siest S; Reiner AP; Gross M; Bis JC; Franke L; Franco OH; Benjamin EJ; Chasman DI; Dupuis J; Snieder H; Dehghan A; Alizadeh BZ
Article: NATURE GENETICS. 2018;50(10):1412-1425
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits
Evangelou E; Warren HR; Mosen-Ansorena D; Mifsu B; Pazoki R; Gao H; Ntritsos G; Dimou N; Cabrer CP; Karaman I; Ng F; Evangelou M; Witkowska K; Tzanis E; Hellwege JN; Giri A; Edwards DRV; Sun YV; Cho K; Gaziano JM; Wilson PWF; Tsao PS; Kovesdy CP; Esko T; Magi R; Milani L; Almgren P; Boutin T; Debette S; Ding J; Giulianini F; Holliday EG; Jackson AU; Li-Gao R; Lin W-Y; Luan J; Mangino M; Oldmeadow C; Prins BP; Qian Y; Sargurupremraj M; Shah N; Surendran P; Theriault S; Verweij N; Willems SM; Zhao J-H; Amouyel P; Connell J; de Mutsert R; Doney ASF; Farrall M; Menni C; Morris AD; Noordam R; Pare G; Poulter NR; Shields DC; Stanton A; Thom S; Abecasis G; Amin N; Arking DE; Ayers KL; Barbieri CM; Batini C; Bis JC; Blake T; Bochud M; Boehnke M; Boerwinkle E; Boomsma DI; Bottinger EP; Braund PS; Brumat M; Campbell A; Campbell H; Chakravarti A; Chambers JC; Chauhan G; Ciullo M; Cocca M; Collins F; Cordell HJ; Davies G; de Borst MH; de Geus EJ; Deary IJ; Deelen J; Del Greco FM; Demirkale CY; Doerr M; Ehret GB; Elosua R; Enroth S; Erzurumluoglu AM; Ferreira T; Franberg M; Franco OH; Gandin I; Gasparini P; Giedraitis V; Gieger C; Girotto G; Goel A; Gow AJ; Gudnason V; Guo X; Gyllensten U; Hamsten A; Harris TB; Harris SE; Hartman CA; Havulinna AS; Hicks AA; Hofer E; Hofman A; Hottenga J-J; Huffman JE; Hwang S-J; Ingelsson E; James A; Jansen R; Jarvelin M-R; Joehanes R; Johansson A; Johnson AD; Joshi PK; Jousilahti P; Jukema JW; Jula A; Kahonen M; Kathiresan S; Keavney BD; Khaw K-T; Knekt P; Knight J; Kolcic I; Kooner JS; Koskinen S; Kristiansson K; Kutalik Z; Laan M; Larson M; Launer LJ; Lehne B; Lehtimaki T; Liewald DCM; Lin L; Lind L; Lindgren CM; Liu Y; Loos RJF; Lopez LM; Lu Y; Lyytikainen L-P; Mahajan A; Mamasoula C; Marrugat J; Marten J; Milaneschi Y; Morgan A; Morris AP; Morrison AC; Munson PJ; Nalls MA; Nandakumar P; Nelson CP; Niiranen T; Nolte IM; Nutile T; Oldehinkel AJ; Oostra BA; O'Reilly PF; Org E; Padmanabhan S; Palmas W; Palotie A; Pattie A; Penninx BWJH; Perola M; Peters A; Polasek O; Pramstaller PP; Nguyen QT; Raitakari OT; Ren M; Rettig R; Rice K; Ridker PM; Ried JS; Riese H; Ripatti S; Robino A; Rose LM; Rotter JI; Rudan I; Ruggiero D; Saba Y; Sala CF; Salomaa V; Samani NJ; Sarin A-P; Schmidt R; Schmidt H; Shrine N; Siscovick D; Smith AV; Snieder H; Sober S; Sorice R; Starr JM; Stott DJ; Strachan DP; Strawbridge RJ; Sundstrom J; Swertz MA; Taylor KD; Teumer A; Tobin MD; Tomaszewski M; Toniolo D; Traglia M; Trompet S; Tuomilehto J; Tzourio C; Uitterlinden AG; Vaez A; van der Most PJ; van Duijn CM; Vergnaud A-C; Verwoert GC; Vitart V; Voelker U; Vollenweider P; Vuckovic D; Watkins H; Wild SH; Willemsen G; Wilson JF; Wright AF; Yao J; Zemunik T; Zhang W; Attia JR; Butterworth AS; Chasman D; Conen D; Cucca F; Danesh J; Hayward C; Howson JMM; Laakso M; Lakatta EG; Langenberg C; Melander O; Mook-Kanamori DO; Palmer CNA; Risch L; Scott RA; Scott RJ; Sever P; Spector TD; van der Harst P; Wareham NJ; Zeggini E; Levy D; Munroe PB; Newton-Cheh C; Brown MJ; Metspalu A; Hung AM; O'Donnell C; Edwards TL; Psaty BM; Tzoulaki I; Barnes MR; Wain LV; Elliott P; Caulfield MJ
Article: NATURE GENETICS. 2018;50(9):1225-1233
Multi-ethnic genome-wide association study for atrial fibrillation
Roselli C; Chaffin MD; Weng L-C; Aeschbacher S; Ahlberg G; Albert CM; Almgren P; Alonso A; Anderson CD; Aragam KG; Arking DE; Barnard J; Bartz TM; Benjamin EJ; Bihlmeyer NA; Bis JC; Bloom HL; Boerwinkle E; Bottinger EB; Brody JA; Calkins H; Campbell A; Cappola TP; Carlquist J; Chasman DI; Chen LY; Chen Y-DI; Choi E-K; Choi SH; Christophersen IE; Chung MK; Cole JW; Conen D; Cook J; Crijns HJ; Cutler MJ; Damrauer SM; Daniels BR; Darbar D; Delgado G; Denny JC; Dichgans M; Doerr M; Dudink EA; Dudley SC; Esa N; Esko T; Eskola M; Fatkin D; Felix SB; Ford I; Franco OH; Geelhoed B; Grewal RP; Gudnason V; Guo X; Gupta N; Gustafsson S; Gutmann R; Hamsten A; Harris TB; Hayward C; Heckbert SR; Hernesniemi J; Hocking LJ; Hofman A; Horimoto ARVR; Huang J; Huang PL; Huffman J; Ingelsson E; Ipek EG; Ito K; Jimenez-Conde J; Johnson R; Jukema JW; Kaeaeb S; Kahonen M; Kamatani Y; Kane JP; Kastrati A; Kathiresan S; Katschnig-Winter P; Kavousi M; Kessler T; Kietselaer BL; Kirchhof P; Kleber ME; Knight S; Krieger JE; Kubo M; Launer LJ; Laurikka J; Lehtimaki T; Leineweber K; Lemaitre RN; Li M; Lim HE; Lin HJ; Lin H; Lind L; Lindgren CM; Lokki M-L; London B; Loos RJF; Low S-K; Lu Y; Lyytikainen L-P; Macfarlane PW; Magnusson PK; Mahajan A; Malik R; Mansur AJ; Marcus GM; Margolin L; Margulies KB; Maerz W; McManus DD; Melander O; Mohanty S; Montgomery JA; Morley MP; Morris AP; Mueller-Nurasyid M; Natale A; Nazarian S; Neumann B; Newton-Cheh C; Niemeijer MN; Nikus K; Nilsson P; Noordam R; Oellers H; Olesen MS; Orho-Melander M; Padmanabhan S; Pak H-N; Pare G; Pedersen NL; Pera J; Pereira A; Porteous D; Psaty BM; Pulit SL; Pullinger CR; Rader DJ; Refsgaard L; Ribases M; Ridker PM; Rienstra M; Risch L; Roden DM; Rosand J; Rosenberg MA; Rost N; Rotter JI; Saba S; Sandhu RK; Schnabel RB; Schramm K; Schunkert H; Schurman C; Scott SA; Seppala I; Shaffer C; Shah S; Shalaby AA; Shim J; Shoemaker MB; Siland JE; Sinisalo J; Sinner MF; Slowik A; Smith AV; Smith BH; Smith JG; Smith JD; Smith NL; Soliman EZ; Sotoodehnia N; Stricker BH; Sun A; Sun H; Svendsen JH; Tanaka T; Tanriverdi K; Taylor KD; Teder-Laving M; Teumer A; Theriault S; Trompet S; Tucker NR; Tveit A; Uitterlinden AG; Van Der Harst P; Van Gelder IC; Van Wagoner DR; Verweij N; Vlachopoulou E; Voelker U; Wang B; Weeke PE; Weijs B; Weiss R; Weiss S; Wells QS; Wiggins KL; Wong JA; Woo D; Worrall BB; Yang P-S; Yao J; Yoneda ZT; Zeller T; Zeng L; Lubitz SA; Lunetta KL; Ellinor PT
Article: INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY. 2018;40(3):251-257
VIIaAT complexes, procoagulant phospholipids, and thrombin generation during postprandial lipemia
Silveira A; Carlo A; Adam M; McLeod O; Lundman P; Boquist S; Woodhams BJ; Hamsten A
Article: NATURE GENETICS. 2018;50(4):524-537
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes
Malik R; Chauhan G; Traylor M; Sargurupremraj M; Okada Y; Mishra A; Rutten-Jacobs L; Giese A-K; van der Laan SW; Gretarsdottir S; Anderson CD; Chong M; Adams HHH; Ago T; Almgren P; Amouyel P; Ay H; Bartz TM; Benavente OR; Bevan S; Boncoraglio GB; Brown RDJ; Butterworth AS; Carrera C; Carty CL; Chasman DI; Chen W-M; Cole JW; Correa A; Cotlarciuc I; Cruchaga C; Danesh J; de Bakker PIW; DeStefano AL; den Hoed M; Duan Q; Engelter ST; Falcone GJ; Gottesman RF; Grewal RP; Gudnason V; Gustafsson S; Haessler J; Harris TB; Hassan A; Havulinna AS; Heckbert SR; Holliday EG; Howard G; Hsu F-C; Hyacinth HI; Ikram MA; Ingelsson E; Irvin MR; Jian X; Jimenez-Conde J; Johnson JA; Jukema JW; Kanai M; Keene KL; Kissela BM; Kleindorfer DO; Kooperberg C; Kubo M; Lange LA; Langefeld CD; Langenberg C; Launer LJ; Lee J-M; Lemmens R; Leys D; Lewis CM; Lin W-Y; Lindgren AG; Lorentzen E; Magnusson PK; Maguire J; Manichaikul A; McArdle PF; Meschia JF; Mitchell BD; Mosley TH; Nalls MA; Ninomiya T; O'Donnell MJ; Psaty BM; Pulit SL; Rannikmae K; Reiner AP; Rexrode KM; Rice K; Rich SS; Ridker PM; Rost NS; Rothwell PM; Rotter JI; Rundek T; Sacco RL; Sakaue S; Sale MM; Salomaa V; Sapkota BR; Schmidt R; Schmidt CO; Schminke U; Sharma P; Slowik A; Sudlow CLM; Tanislav C; Tatlisumak T; Taylor KD; Thijs VNS; Thorleifsson G; Thorsteinsdottir U; Tiedt S; Trompet S; Tzourio C; van Duijn CM; Walters M; Wareham NJ; Wassertheil-Smoller S; Wilson JG; Wiggins KL; Yang Q; Yusuf S; Bis JC; Pastinen T; Ruusalepp A; Schadt EE; Koplev S; Bjorkegren JLM; Codoni V; Civelek M; Smith NL; Tregouet DA; Christophersen IE; Roselli C; Lubitz SA; Ellinor PT; Tai ES; Kooner JS; Kato N; He J; van der Harst P; Elliott P; Chambers JC; Takeuchi F; Johnson AD; Sanghera DK; Melander O; Jern C; Strbian D; Fernandez-Cadenas I; Longstreth WTJ; Rolfs A; Hata J; Woo D; Rosand J; Pare G; Hopewell JC; Saleheen D; Stefansson K; Worrall BB; Kittner SJ; Seshadri S; Fornage M; Markus HS; Howson JMM; Kamatani Y; Debette S; Dichgans M
Article: NATURE COMMUNICATIONS. 2018;9(1):987
Genome-wide analysis yields new loci associating with aortic valve stenosis
Helgadottir A; Thorleifsson G; Gretarsdottir S; Stefansson OA; Tragante V; Thorolfsdottir RB; Jonsdottir I; Bjornsson T; Steinthorsdottir V; Verweij N; Nielsen JB; Zhou W; Folkersen L; Martinsson A; Heydarpour M; Prakash S; Oskarsson G; Gudbjartsson T; Geirsson A; Olafsson I; Sigurdsson EL; Almgren P; Melander O; Franco-Cereceda A; Hamsten A; Fritsche L; Lin M; Yang B; Hornsby W; Guo D; Brummett CM; Abecasis G; Mathis M; Milewicz D; Body SC; Eriksson P; Willer CJ; Hveem K; Newton-Cheh C; Smith JG; Danielsen R; Thorgeirsson G; Thorsteinsdottir U; Gudbjartsson DF; Holm H; Stefansson K
Article: JOURNAL OF PROTEOME RESEARCH. 2018;17(2):870-878
Increased Levels of Circulating Fatty Acids Are Associated with Protective Effects against Future Cardiovascular Events in Nondiabetics
Kamleh MA; McLeod O; Checa A; Baldassarre D; Veglia F; Gertow K; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Silveira A; Orvik J; Hamsten A; Wheelock CE
Article: ATHEROSCLEROSIS. 2018;269:129-137
Association of lifelong occupation and educational level with subclinical atherosclerosis in different European regions. Results from the IMPROVE study
Tedesco CC; Veglia F; de Faire U; Kurl S; Smit AJ; Rauramaa R; Giral P; Amato M; Bonomi A; Ravani A; Frigerio B; Castelnuovo S; Sansaro D; Mannarino E; Humphries SE; Hamsten A; Tremoli E; Baldassarre D
Article: OPEN HEART. 2018;5(1):e000807
Plasma cytokines and risk of coronary heart disease in the PROCARDIS study
Clarke R; Valdes-Marquez E; Hill M; Gordon J; Farrall M; Hamsten A; Watkins H; Hopewell JC
Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444
Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke
Mahdessian H; Matic LP; Lengquist M; Gertow K; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Hamsten A; Eriksson P; Hedin U; Malarstig A
Article: ATHEROSCLEROSIS. 2017;266:196-204
Identification of a novel proinsulin-associated SNP and demonstration that proinsulin is unlikely to be a causal factor in subclinical vascular remodelling using Mendelian randomisation
Strawbridge RJ; Silveira A; den Hoed M; Gustafsson S; Luan J; Rybin D; Dupuis J; Li-Gao R; Kavousi M; Dehghan A; Haljas K; Lahti J; Gadin JR; Backlund A; de Faire U; Gertow K; Giral P; Goel A; Humphries SE; Kurl S; Langenberg C; Lannfelt LL; Lind L; Lindgren CCM; Mannarino E; Mook-Kanamori DO; Morris AP; de Mutsert R; Rauramaa R; Saliba-Gustafsson P; Sennblad B; Smit AJ; Syvanen A-C; Tremoli E; Veglia F; Zethelius B; Bjorck HM; Eriksson JG; Hofman A; Franco OH; Watkins H; Jukema JW; Florez JC; Wareham NJ; Meigs JB; Ingelsson E; Baldassarre D; Hamsten A
Article: DIABETES. 2017;66(11):2888-2902
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Scott RA; Scott LJ; Maegi R; Marullo L; Gaulton KJ; Kaakinen M; Pervjakova N; Pers TH; Johnson AD; Eicher JD; Jackson AU; Ferreira T; Lee Y; Ma C; Steinthorsdottir V; Thorleifsson G; Qi L; Van Zuydam NR; Mahajan A; Chen H; Almgren P; Voight BF; Grallert H; Mueller-Nurasyid M; Ried JS; Rayner NW; Robertson N; Karssen LC; Van Leeuwen EM; Willems SM; Fuchsberger C; Kwan P; Teslovich TM; Chanda P; Li M; Lu Y; Dina C; Thuillier D; Yengo L; Jiang L; Sparso T; Kestler HA; Chheda H; Eisele L; Gustafsson S; Franberg M; Strawbridge RJ; Benediktsson R; Hreidarsson AB; Kong A; Sigurdsson G; Kerrison ND; Luan J; Liang L; Meitinger T; Roden M; Thorand B; Esko T; Mihailov E; Fox C; Liu C-T; Rybin D; Isomaa B; Lyssenko V; Tuomi T; Couper DJ; Pankow JS; Grarup N; Have CT; Jorgensen ME; Jorgensen T; Linneberg A; Cornelis MC; Van Dam RM; Hunter DJ; Kraft P; Sun Q; Edkins S; Owen KR; Perry JRB; Wood AR; Zeggini E; Tajes-Fernandes J; Abecasis GR; Bonnycastle LL; Chines PS; Stringham HM; Koistinen HA; Kinnunen L; Sennblad B; Muehleisen TW; Noethen MM; Pechlivanis S; Baldassarre D; Gertow K; Humphries SE; Tremoli E; Klopp N; Meyer J; Steinbach G; Wennauer R; Eriksson JG; Mannisto S; Peltonen L; Tikkanen E; Charpentier G; Eury E; Lobbens S; Gigante B; Leander K; McLeod O; Bottinger EP; Gottesman O; Ruderfer D; Blueher M; Kovacs P; Tonjes A; Maruthur NM; Scapoli C; Erbel R; Joeckel K-H; Moebus S; De Faire U; Hamsten A; Stumvoll M; Deloukas P; Donnelly PJ; Frayling TM; Hattersley AT; Ripatti S; Salomaa V; Pedersen NL; Boehm BO; Bergman RN; Collins FS; Mohlke KL; Tuomilehto J; Hansen T; Pedersen O; Barroso I; Lannfelt L; Ingelsson E; Lind L; Lindgren CM; Cauchi S; Froguel P; Loos RJF; Balkau B; Boeing H; Franks PW; Gurrea AB; Palli D; Van der Schouw YT; Altshuler D; Groop LC; Langenberg C; Wareham NJ; Sijbrands E; Van Duijn CM; Florez JC; Meigs JB; Boerwinkle E; Gieger C; Strauch K; Metspalu A; Morris AD; Palmer CNA; Hu FB; Thorsteinsdottir U; Stefansson K; Dupuis J; Morris AP; Boehnke M; McCarthy MI; Prokopenko I
Article: PLOS MEDICINE. 2017;14(9):e1002383
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis
Wheeler E; Leong A; Liu C-T; Hivert M-F; Strawbridge RJ; Podmore C; Li M; Yao J; Sim X; Hong J; Chu AY; Zhang W; Wang X; Chen P; Maruthur NM; Porneala BC; Sharp SJ; Jia Y; Kabagambe EK; Chang L-C; Chen W-M; Elks CE; Evans DS; Fan Q; Giulianini F; Go MJ; Hottenga J-J; Hu Y; Jackson AU; Kanoni S; Kim YJ; Kleber ME; Ladenvall C; Lecoeur C; Lim S-H; Lu Y; Mahajan A; Marzi C; Nalls MA; Navarro P; Nolte IM; Rose LM; Rybin DV; Sanna S; Shi Y; Stram DO; Takeuchi F; Tan SP; van der Most PJ; Van Vliet-Ostaptchouk JV; Wong A; Yengo L; Zhao W; Goel A; Martinez Larrad MT; Radke D; Salo P; Tanaka T; van Iperen EPA; Abecasis G; Afaq S; Alizadeh BZ; Bertoni AG; Bonnefond A; Boettcher Y; Bottinger EP; Campbell H; Carlson OD; Chen C-H; Cho YS; Garvey WT; Gieger C; Goodarzi MO; Grallert H; Hamsten A; Hartman CA; Herder C; Hsiung CA; Huang J; Igase M; Isono M; Katsuya T; Khor C-C; Kiess W; Kohara K; Kovacs P; Lee J; Lee W-J; Lehne B; Li H; Liu J; Lobbens S; Luang J; Lyssenko V; Meitinger T; Miki T; Miljkovic I; Moon S; Mulas A; Mueller G; Mueller-Nurasyid M; Nagaraja R; Nauck M; Pankow JS; Polasek O; Prokopenko I; Ramos PS; Rasmussen-Torvik L; Rathmann W; Rich SS; Robertson NR; Roden M; Roussel R; Rudan I; Scott RA; Scott WR; Sennblad B; Siscovick DS; Strauch K; Sun L; Swertz M; Tajuddin SM; Taylor KD; Teo Y-Y; Tham YC; Toenjes A; Wareham NJ; Willemsen G; Wilsgaard T; Hingorani AD; Egan J; Ferrucci L; Hovingh GK; Jula A; Kivimaki M; Kumari M; Njolstad I; Palmer CNA; Serrano Rios M; Stumvoll M; Watkins H; Aung T; Blueher M; Boehnke M; Boomsma DI; Bornstein SR; Chambers JC; Chasman DI; Chen Y-DI; Chen Y-T; Cheng C-Y; Cucca F; de Geus EJC; Deloukas P; Evans MK; Fornage M; Friedlander Y; Froguel P; Groop L; Gross MD; Harris TB; Hayward C; Heng C-K; Ingelsson E; Kato N; Kim B-J; Koh W-P; Kooner JS; Koerner A; Kuh D; Kuusisto J; Laakso M; Lin X; Liu Y; Loos RJF; Magnusson PKE; Maerz W; McCarthy MI; Oldehinkel AJ; Ong KK; Pedersen NL; Pereira MA; Peters A; Ridker PM; Sabanayagam C; Sale M; Saleheen D; Saltevo J; Schwarz PEH; Sheu WHH; Snieder H; Spector TD; Tabara Y; Tuomilehto J; van Dam RM; Wilson JG; Wilson JF; Wolffenbuttel BHR; Wong TY; Wu J-Y; Yuan J-M; Zonderman AB; Soranzo N; Guo X; Roberts DJ; Florez JC; Sladek R; Dupuis J; Morris AP; Tai E-S; Selvin E; Rotter JI; Langenberg C; Barroso I; Meigs JB
Article: HYPERTENSION. 2017;70(3):E4-e19
Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney
Wain LV; Vaez A; Jansen R; Joehanes R; van der Most PJ; Erzurumluoglu AM; O'Reilly PF; Cabrera CP; Warren HR; Rose LM; Verwoert GC; Hottenga J-J; Strawbridge RJ; Esko T; Arking DE; Hwang S-J; Guo X; Kutalik Z; Trompet S; Shrine N; Teumer A; Ried JS; Bis JC; Smith AV; Amin N; Nolte IM; Lyytikainen L-P; Mahajan A; Wareham NJ; Hofer E; Joshi PK; Kristiansson K; Traglia M; Havulinna AS; Goel A; Nalls MA; Sober S; Vuckovic D; Luan J; Del Greco M F; Ayers KL; Marrugat J; Ruggiero D; Lopez LM; Niiranen T; Enroth S; Jackson AU; Nelson CP; Huffman JE; Zhang W; Marten J; Gandin I; Harris SE; Zemunik T; Lu Y; Evangelou E; Shah N; de Borst MH; Mangino M; Prins BP; Campbell A; Li-Gao R; Chauhan G; Oldmeadow C; Abecasis G; Abedi M; Barbieri CM; Barnes MR; Batini C; Beilby J; Blake T; Boehnke M; Bottinger EP; Braund PS; Brown M; Brumat M; Campbell H; Chambers JC; Cocca M; Collins F; Connell J; Cordell HJ; Damman JJ; Davies G; de Geus EJ; de Mutsert R; Deelen J; Demirkale Y; Doney ASF; Dorr M; Farrall M; Ferreira T; Franberg M; Gao H; Giedraitis V; Gieger C; Giulianini F; Gow AJ; Hamsten A; Harris TB; Hofman A; Holliday EG; Hui J; Jarvelin M-R; Johansson A; Johnson AD; Jousilahti P; Jula A; Kahonen M; Kathiresan S; Khaw K-T; Kolcic I; Koskinen S; Langenberg C; Larson M; Launer LJ; Lehne B; Liewald DCM; Lin L; Lind L; Mach F; Mamasoula C; Menni C; Mifsud B; Milaneschi Y; Morgan A; Morris AD; Morrison AC; Munson PJ; Nandakumar P; Quang TN; Nutile T; Oldehinkel AJ; Oostra BA; Org E; Padmanabhan S; Palotie A; Pare G; Pattie A; Penninx BWJH; Poulter N; Pramstaller PP; Raitakari OT; Ren M; Rice K; Ridker PM; Riese H; Ripatti S; Robino A; Rotter JI; Rudan I; Saba Y; Saint Pierre A; Sala CF; Sarin A-P; Schmidt R; Scott R; Seelen MA; Shields DC; Siscovick D; Sorice R; Stanton A; Stott DJ; Sundstrom J; Swertz M; Taylor KD; Thom S; Tzoulaki I; Tzourio C; Uitterlinden AG; Volker U; Vollenweider P; Wild S; Willemsen G; Wright AF; Yao J; Theriault S; Conen D; Attia J; Sever P; Debette S; Mook-Kanamori DO; Zeggini E; Spector TD; van der Harst P; Palmer CNA; Vergnaud A-C; Loos RJF; Polasek O; Starr JM; Girotto G; Hayward C; Kooner JS; Lindgren CM; Vitart V; Samani NJ; Tuomilehto J; Gyllensten U; Knekt P; Deary IJ; Ciullo M; Elosua R; Keavney BD; Hicks AA; Scott RA; Gasparini P; Laan M; Liu Y; Watkins H; Hartman CA; Salomaa V; Toniolo D; Perola M; Wilson JF; Schmidt H; Zhao JH; Lehtimaki T; van Duijn CM; Gudnason V; Psaty BM; Peters A; Rettig R; James A; Jukema JW; Strachan DP; Palmas W; Metspalu A; Ingelsson E; Boomsma DI; Franco OH; Bochud M; Newton-Cheh C; Munroe PB; Elliott P; Chasman DI; Chakravarti A; Knight J; Morris AP; Levy D; Tobin MD; Snieder H; Caulfield MJ; Ehret GB; Alistair TY; Betholdson J-P; Xiao L
Article: ATHEROSCLEROSIS. 2017;263:412-419
Carotid plaque-thickness and common carotid IMT show additive value in cardiovascular risk prediction and reclassification
Amato M; Veglia F; de Faire U; Giral P; Rauramaa R; Smit AJ; Kurl S; Ravani A; Frigerio B; Sansaro D; Bonomi A; Tedesco CC; Castelnuovo S; Mannarino E; Humphries SE; Hamsten A; Tremoli E; Baldassarre D
Article: PLOS COMPUTATIONAL BIOLOGY. 2017;13(6):e1005556
Fast and general tests of genetic interaction for genome-wide association studies
Franberg M; Strawbridge RJ; Hamster A; de Faire U; Lagergren J; Sennblad B
Article: NATURE GENETICS. 2017;49(6):946-952
Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation
Christophersen IE; Rienstra M; Roselli C; Yin X; Geelhoed B; Barnard J; Lin H; Arking DE; Smith AV; Albert CM; Chaffin M; Tucker NR; Li M; Klarin D; Bihlmeyer NA; Low S-K; Weeke PE; Mueller-Nurasyid M; Smith JG; Brody JA; Niemeijer MN; Doerr M; Trompet S; Huffman J; Gustafsson S; Schurmann C; Kleber ME; Lyytikainen L-P; Seppala I; Malik R; Horimoto ARVR; Perez M; Sinisalo J; Aeschbacher S; Theriault S; Yao J; Radmanesh F; Weiss S; Teumer A; Choi SH; Weng L-C; Clauss S; Deo R; Rader DJ; Shah SH; Sun A; Hopewell JC; Debette S; Chauhan G; Yang Q; Worrall BB; Pare G; Kamatani Y; Hagemeijer YP; Verweij N; Siland JE; Kubo M; Smith JD; Van Wagoner DR; Bis JC; Perz S; Psaty BM; Ridker PM; Magnani JW; Harris TB; Launer LJ; Shoemaker MB; Padmanabhan S; Haessler J; Bartz TM; Waldenberger M; Lichtner P; Arendt M; Krieger JE; Kahonen M; Risch L; Mansur AJ; Peters A; Smith BH; Lind L; Scott SA; Lu Y; Bottinger EB; Hernesniemi J; Lindgren CM; Wong JA; Huang J; Eskola M; Morris AP; Ford I; Reiner AP; Delgado G; Chen LY; Chen Y-DI; Sandhu RK; Li M; Boerwinkle E; Eisele L; Lannfelt L; Rost N; Anderson CD; Taylor KD; Campbell A; Magnusson PK; Porteous D; Hocking LJ; Vlachopoulou E; Pedersen NL; Nikus K; Orho-Melander M; Hamsten A; Heeringa J; Denny JC; Kriebel J; Darbar D; Newton-Cheh C; Shaffer C; Macfarlane PW; Heilmann-Heimbach S; Almgren P; Huang PL; Sotoodehnia N; Soliman EZ; Uitterlinden AG; Hofman A; Franco OH; Voelker U; Joeckel K-H; Sinner MF; Lin HJ; Guo X; Dichgans M; Ingelsson E; Kooperberg C; Melander O; Loos RJF; Laurikka J; Conen D; Rosand J; van der Harst P; Lokki M-L; Kathiresan S; Pereira A; Jukema JW; Hayward C; Rotter JI; Maerz W; Lehtimaki T; Stricker BH; Chung MK; Felix SB; Gudnason V; Alonso A; Roden DM; Kaeaeb S; Chasman DI; Heckbert SR; Benjamin EJ; Tanaka T; Lunetta KL; Lubitz SA; Ellinor PT
Article: NATURE COMMUNICATIONS. 2017;8:14977
Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits
Justice AE; Winkler TW; Feitosa MF; Graff M; Fisher VA; Young K; Barata L; Deng X; Czajkowski J; Hadley D; Ngwa JS; Ahluwalia TS; Chu AY; Heard-Costa NL; Lim E; Perez J; Eicher JD; Kutalik Z; Xue L; Mahajan A; Renstrom F; Wu J; Qi Q; Ahmad S; Alfred T; Amin N; Bielak LF; Bonnefond A; Bragg J; Cadby G; Chittani M; Coggeshall S; Corre T; Direk N; Eriksson J; Fischer K; Gorski M; Harder MN; Horikoshi M; Huang T; Huffman JE; Jackson AU; Justesen JM; Kanoni S; Kinnunen L; Kleber ME; Komulainen P; Kumari M; Lim U; Luan J; Lyytikainen L-P; Mangino M; Manichaikul A; Marten J; Middelberg RPS; Mueller-Nurasyid M; Navarro P; Perusse L; Pervjakova N; Sarti C; Smith AV; Smith JA; Stancakova A; Strawbridge RJ; Stringham HM; Sung YJ; Tanaka T; Teumer A; Trompet S; van der Laan SW; van der Most PJ; Van Vliet-Ostaptchouk JV; Vedantam SL; Verweij N; Vink JM; Vitart V; Wu Y; Yengo L; Zhang W; Zhao JH; Zimmermann ME; Zubair N; Abecasis GR; Adair LS; Afaq S; Afzal U; Bakker SJL; Bartz TM; Beilby J; Bergman RN; Bergmann S; Biffar R; Blangero J; Boerwinkle E; Bonnycastle LL; Bottinger E; Braga D; Buckley BM; Buyske S; Campbell H; Chambers JC; Collins FS; Curran JE; de Borst GJ; de Craen AJM; de Geus EJC; Dedoussis G; Delgado GE; den Ruijter HM; Eiriksdottir G; Eriksson AL; Esko T; Faul JD; Ford I; Forrester T; Gertow K; Gigante B; Glorioso N; Gong J; Grallert H; Grammer TB; Grarup N; Haitjema S; Hallmans G; Hamsten A; Hansen T; Harris TB; Hartman CA; Hassinen M; Hastie ND; Heath AC; Hernandez D; Hindorff L; Hocking LJ; Hollensted M; Holmen OL; Homuth G; Hottenga JJ; Huang J; Hung J; Hutri-Kahonen N; Ingelsson E; James AL; Jansson J-O; Jarvelin M-R; Jhun MA; Jorgensen ME; Juonala M; Kahonen M; Karlsson M; Koistinen HA; Kolcic I; Kolovou G; Kooperberg C; Kramer BK; Kuusisto J; Kvaloy K; Lakka TA; Langenberg C; Launer LJ; Leander K; Lee NR; Lind L; Lindgren CM; Linneberg A; Lobbens S; Loh M; Lorentzon M; Luben R; Lubke G; Ludolph-Donislawski A; Lupoli S; Madden PAF; Mannikko R; Marques-Vidal P; Martin NG; McKenzie CA; McKnight B; Mellstrom D; Menni C; Montgomery GW; Musk AWB; Narisu N; Nauck M; Nolte IM; Oldehinkel AJ; Olden M; Ong KK; Padmanabhan S; Peyser PA; Pisinger C; Porteous DJ; Raitakari OT; Rankinen T; Rao DC; Rasmussen-Torvik LJ; Rawal R; Rice T; Ridker PM; Rose LM; Bien SA; Rudan I; Sanna S; Sarzynski MA; Sattar N; Savonen K; Schlessinger D; Scholtens S; Schurmann C; Scott RA; Sennblad B; Siemelink MA; Silbernagel G; Slagboom PE; Snieder H; Staessen JA; Stott DJ; Swertz MA; Swift AJ; Taylor KD; Tayo BO; Thorand B; Thuillier D; Tuomilehto J; Uitterlinden AG; Vandenput L; Vohl M-C; Volzke H; Vonk JM; Waeber G; Waldenberger M; Westendorp RGJ; Wild S; Willemsen G; Wolffenbuttel BHR; Wong A; Wright AF; Zhao W; Zillikens MC; Baldassarre D; Balkau B; Bandinelli S; Boger CA; Boomsma DI; Bouchard C; Bruinenberg M; Chasman DI; Chen Y-DI; Chines PS; Cooper RS; Cucca F; Cusi D; de Faire U; Ferrucci L; Franks PW; Froguel P; Gordon-Larsen P; Grabe H-J; Gudnason V; Haiman CA; Hayward C; Hveem K; Johnson AD; Jukema W; Kardia SLR; Kivimaki M; Kooner JS; Kuh D; Laakso M; Lehtimaki T; Le Marchand L; Marz W; McCarthy MI; Metspalu A; Morris AP; Ohlsson C; Palmer LJ; Pasterkamp G; Pedersen O; Peters A; Peters U; Polasek O; Psaty BM; Qi L; Rauramaa R; Smith BH; Sorensen TIA; Strauch K; Tiemeier H; Tremoli E; Van der Harst P; Vestergaard H; Vollenweider P; Wareham NJ; Weir DR; Whitfield JB; Wilson JF; Tyrrell J; Frayling TM; Barroso I; Boehnke M; Deloukas P; Fox CS; Hirschhorn JN; Hunter DJ; Spector TD; Strachan DP; van Duijn CM; Heid IM; Mohlke KL; Marchini J; Loos RJF; Kilpelainen TO; Liu C-T; Borecki IB; North KE; Cupples LA
Article: PLOS GENETICS. 2017;13(4):e1006706
Mapping of 79 loci for 83 plasma protein biomarkers in cardiovascular disease
Folkersen L; Fauman E; Sabater-Lleal M; Strawbridge RJ; Franberg M; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Enroth S; Johansson A; Enroth SB; Gustafsson S; Lind L; Lindgren C; Morris AP; Giedraitis V; Silveira A; Franco-Cereceda A; Tremoli E; Gyllensten U; Ingelsson E; Brunak S; Eriksson P; Ziemek D; Hamsten A; Malarstig A
Article: NATURE GENETICS. 2017;49(3):403-415
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk
Warren HR; Evangelou E; Cabrera CP; Gao H; Ren M; Mifsud B; Ntalla I; Surendran P; Liu C; Cook JP; Kraja AT; Drenos F; Loh M; Verweij N; Marten J; Karaman I; Lepe MPS; O'Reilly PF; Knight J; Snieder H; Kato N; He J; Tai ES; Said MA; Porteous D; Alver M; Poulter N; Farrall M; Gansevoort RT; Padmanabhan S; Magi R; Stanton A; Connell J; Bakker SJL; Metspalu A; Shields DC; Thom S; Brown M; Sever P; Esko T; Hayward C; van der Harst P; Saleheen D; Chowdhury R; Chambers JC; Chasman DI; Chakravarti A; Newton-Cheh C; Lindgren CM; Levy D; Kooner JS; Keavney B; Tomaszewski M; Samani NJ; Howson JMM; Tobin MD; Munroe PB; Ehret GB; Wain LV; Barnes MR; Tzoulaki J; Caulfield MJ; Elliott P; Wain LV; Vaez A; Jansen R; Joehanes R; van der Most PJ; Erzurumluoglu AM; O'Reilly P; Cabrera CP; Warren HR; Rose LM; Verwoert GC; Hottenga J-J; Strawbridge RJ; Esko T; Arking DE; Hwang S-J; Guo X; Kutalik Z; Trompet S; Shrine N; Teumer A; Ried JS; Bis JC; Smith AV; Amin N; Nolte IM; Lyytikainen L-P; Mahajan A; Wareham NJ; Hofer E; Joshi PK; Kristiansson K; Traglia M; Havulinna AS; Goel A; Nalls MA; Sober S; Vuckovic D; Luan J; Del Greco M F; Ayers KL; Marrugat J; Ruggiero D; Lopez LM; Niiranen T; Enroth S; Jackson AU; Nelson CP; Huffman JE; Zhang W; Marten J; Gandin I; Harris SE; Zemonik T; Lu Y; Evangelou E; Shah N; de Borst MH; Mangino M; Prins BP; Campbell A; Li-Gao R; Chauhan G; Oldmeadow C; Abecasis G; Abedi M; Barbieri CM; Barnes MR; Batini C; Blake T; Boehnke M; Bottinger EP; Braund PS; Brown M; Brumat M; Campbell H; Chambers JC; Cocca M; Collins F; Connell J; Cordell HJ; Damman JJ; Davies G; de Geus EJ; de Mutsert R; Deelen J; Demirkale Y; Doney ASF; Dorr M; Farrall M; Ferreira T; Franberg M; Gao H; Giedraitis V; Gieger C; Giulianini F; Gow AJ; Hamsten A; Harris TB; Hofman A; Holliday EG; Jarvelin M-R; Johansson A; Johnson AD; Jousilahti P; Jula A; Kahonen M; Kathiresan S; Khaw K-T; Kolcic I; Koskinen S; Langenberg C; Larson M; Launer LJ; Lehne B; Liewald DCM; Lin L; Lind L; Mach F; Mamasoula C; Menni C; Mifsud B; Milaneschi Y; Morgan A; Morris AD; Morrison AC; Munson PJ; Nandakumar P; Quang TN; Nutile T; Oldehinkel AJ; Oostra BA; Org E; Padmanabhan S; Palotie A; Pare G; Pattie A; Penninx BWJH; Poulter N; Pramstaller PP; Raitakari OT; Ren M; Rice K; Ridker PM; Riese H; Ripatti S; Robino A; Rotter JI; Rudan I; Saba Y; Saint Pierre A; Sala CF; Sarin A-P; Schmidt R; Scott R; Seelen MA; Shields DC; Siscovick D; Sorice R; Stanton A; Stott DJ; Sundstrom J; Swertz M; Taylor KD; Thom S; Tzoulaki I; Tzourio C; Uitterlinden AG; Volker U; Vollenweider P; Wild S; Willemsen G; Wright AF; Yao J; Theriault S; Conen D; John A; Sever P; Debette S; Mook-Kanamori DO; Zeggini E; Spector TD; van der Harst P; Palmer CNA; Vergnaud A-C; Loos RJF; Polasek O; Starr JM; Girotto G; Hayward C; Kooner JS; Lindgren CM; Vitart V; Samani NJ; Tuomilehto J; Gyllensten U; Knekt P; Deary IJ; Ciullo M; Elosua R; Keavney BD; Hicks AA; Scott RA; Gasparini P; Laan M; Liu Y; Watkins H; Hartman CA; Salomaa V; Toniolo D; Perola M; Wilson JF; Schmidt H; Zhao JH; Lehtimaki T; van Duijn CM; Gudnason V; Psaty BM; Peters A; Rettig R; James A; Jukema JW; Strachan DP; Palmas W; Metspalu A; Ingelsson E; Boomsma DI; Franco OH; Bochud M; Newton-Cheh C; Munroe PB; Elliott P; Chasman DI; Chakravarti A; Knight J; Morris AP; Levy D; Tobin MD; Snieder H; Caulfield MJ; Ehret GB
Article: HUMAN MOLECULAR GENETICS. 2017;26(3):637-649
Genome- wide association study with additional genetic and post-transcriptional analyses reveals novel regulators of plasma factor XI levels
Sennblad B; Basu S; Mazur J; Suchon P; Martinez-Perez A; Vlieg AVH; Vinh T; Li Y; Gadin JR; Tang W; Grossman V; de Haan HG; Handin N; Silveira A; Carlos Souto J; Franco-Cereceda A; Morange P-E; Gagnon F; Manuel Soria J; Eriksson P; Hamsten A; Maegdefessel L; Rosendaal FR; Wild P; Folsom AR; Tregouet D-A; Sabater-Lleal M
Article: PLOS ONE. 2017;12(1):e0167742
Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study
de Vries PS; Sabater-Lleal M; Chasman DI; Trompet S; Ahluwalia TS; Teumer A; Kleber ME; Chen M-H; Wang JJ; Attia JR; Marioni RE; Steri M; Weng L-C; Pool R; Grossmann V; Brody JA; Venturini C; Tanaka T; Rose LM; Oldmeadow C; Mazur J; Basu S; Franberg M; Yang Q; Ligthart S; Hottenga JJ; Rumley A; Mulas A; de Craen AJM; Grotevendt A; Taylor KD; Delgado GE; Kifley A; Lopez LM; Berentzen TL; Mangino M; Bandinelli S; Morrison AC; Hamsten A; Tofler G; de Maat MPM; Draisma HHM; Lowe GD; Zoledziewska M; Sattar N; Lackner KJ; Voelker U; McKnight B; Huang J; Holliday EG; McEvoy MA; Starr JM; Hysi PG; Hernandez DG; Guan W; Rivadeneira F; McArdle WL; Slagboom PE; Zeller T; Psaty BM; Uitterlinden AG; de Geus EJC; Stott DJ; Binder H; Hofman A; Franco OH; Rotter JI; Ferrucci L; Spector TD; Deary IJ; Maerz W; Greinacher A; Wild PS; Cucca F; Boomsma DI; Watkins H; Tang W; Ridker PM; Jukema JW; Scott RJ; Mitchell P; Hansen T; O'Donnell CJ; Smith NL; Strachan DP; Dehghan A
Article: BLOOD. 2016;128(23):e59-e66
PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study
Bruzelius M; Iglesias MJ; Hong M-G; Sanchez-Rivera L; Gyorgy B; Carlos Souto J; Franberg M; Fredolini C; Strawbridge RJ; Holmstrom M; Hamsten A; Uhlen M; Silveira A; Manuel Soria J; Smadja DM; Butler LM; Schwenk JM; Morange P-E; Tregouet D-A; Odeberg J
Article: NATURE COMMUNICATIONS. 2016;7:13357
A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape
Ried JS; Jeff JM; Chu AY; Bragg-Gresham JL; van Dongen J; Huffman JE; Ahluwalia TS; Cadby G; Eklund N; Eriksson J; Esko T; Feitosa MF; Goel A; Gorski M; Hayward C; Heard-Costa NL; Jackson AU; Jokinen E; Kanoni S; Kristiansson K; Kutalik Z; Lahti J; Luan J; Maegi R; Mahajan A; Mangino M; Medina-Gomez C; Monda KL; Nolte IM; Perusse L; Prokopenko I; Qi L; Rose LM; Salvi E; Smith MT; Snieder H; Stancakova A; Sung YJ; Tachmazidou I; Teumer A; Thorleifsson G; van der Harst P; Walker RW; Wang SR; Wild SH; Willems SM; Wong A; Zhang W; Albrecht E; Alves AC; Bakker SJL; Barlassina C; Bartz TM; Beilby J; Bellis C; Bergman RN; Bergmann S; Blangero J; Blueher M; Boerwinkle E; Bonnycastle LL; Bornstein SR; Bruinenberg M; Campbell H; Chen Y-DI; Chiang CWK; Chines PS; Collins FS; Cucca F; Cupples LA; D'Avila F; de Geus EJC; Dedoussis G; Dimitriou M; Doering A; Eriksson JG; Farmaki A-E; Farrall M; Ferreira T; Fischer K; Forouhi NG; Friedrich N; Gjesing AP; Glorioso N; Graff M; Grallert H; Grarup N; Graessler J; Grewal J; Hamsten A; Harder MN; Hartman CA; Hassinen M; Hastie N; Hattersley AT; Havulinna AS; Heliovaara M; Hillege H; Hofman A; Holmen O; Homuth G; Hottenga J-J; Hui J; Husemoen LL; Hysi PG; Isaacs A; Ittermann T; Jalilzadeh S; James AL; Jorgensen T; Jousilahti P; Jula A; Justesen JM; Justice AE; Kahonen M; Karaleftheri M; Khaw KT; Keinanen-Kiukaanniemi SM; Kinnunen L; Knekt PB; Koistinen HA; Kolcic I; Kooner IK; Koskinen S; Kovacs P; Kyriakou T; Laitinen T; Langenberg C; Lewin AM; Lichtner P; Lindgren CM; Lindstrom J; Linneberg A; Lorbeer R; Lorentzon M; Luben R; Lyssenko V; Mannisto S; Manunta P; Leach IM; McArdle WL; Mcknight B; Mohlke KL; Mihailov E; Milani L; Mills R; Montasser ME; Morris AP; Mueller G; Musk AW; Narisu N; Ong KK; Oostra BA; Osmond C; Palotie A; Pankow JS; Paternoster L; Penninx BW; Pichler I; Pilia MG; Polasek O; Pramstaller PP; Raitakari OT; Rankinen T; Rao DC; Rayner NW; Ribel-Madsen R; Rice TK; Richards M; Ridker PM; Rivadeneira F; Ryan KA; Sanna S; Sarzynski MA; Scholtens S; Scott RA; Sebert S; Southam L; Sparso TH; Steinthorsdottir V; Stirrups K; Stolk RP; Strauch K; Stringham HM; Swertz MA; Swift AJ; Toenjes A; Tsafantakis E; van der Most PJ; Van Vliet-Ostaptchouk JV; Vandenput L; Vartiainen E; Venturini C; Verweij N; Viikari JS; Vitart V; Vohl M-C; Vonk JM; Waeber G; Widen E; Willemsen G; Wilsgaard T; Winkler TW; Wright AF; Yerges-Armstrong LM; Zhao JH; Zillikens MC; Boomsma DI; Bouchard C; Chambers JC; Chasman DI; Cusi D; Gansevoort RT; Gieger C; Hansen T; Hicks AA; Hu F; Hveem K; Jarvelin M-R; Kajantie E; Kooner JS; Kuh D; Kuusisto J; Laakso M; Lakka TA; Lehtimaeki T; Metspalu A; Njolstad I; Ohlsson C; Oldehinkel AJ; Palmer LJ; Pedersen O; Perola M; Peters A; Psaty BM; Puolijoki H; Rauramaa R; Rudan I; Salomaa V; Schwarz PEH; Shudiner AR; Smit JH; Sorensen TIA; Spector TD; Stefansson K; Stumvoll M; Tremblay A; Tuomilehto J; Uitterlinden AG; Uusitupa M; Voelker U; Vollenweider P; Wareham NJ; Watkins H; Wilson JF; Zeggini E; Abecasis GR; Boehnke M; Borecki IB; Deloukas P; van Duijn CM; Fox C; Groop LC; Heid IM; Hunter DJ; Kaplan RC; McCarthy MI; North KE; O'Connell JR; Schlessinger D; Thorsteinsdottir U; Strachan DP; Frayling T; Hirschhorn JN; Mueller-Nurasyid M; Loos RJF
Article: NATURE GENETICS. 2016;48(11):1303-1312
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps
Iotchkova V; Huang J; Morris JA; Jain D; Barbieri C; Walter K; Min JL; Chen L; Astle W; Cocca M; Deelen P; Elding H; Farmaki A-E; Franklin CS; Franberg M; Gaunt TR; Hofman A; Jiang T; Kleber ME; Lachance G; Luan J; Malerba G; Matchan A; Mead D; Memari Y; Ntalla I; Panoutsopoulou K; Pazoki R; Perry JRB; Rivadeneira F; Sabater-Lleal M; Sennblad B; Shin S-Y; Southam L; Traglia M; van Dijk F; van Leeuwen EM; Zaza G; Zhang W; Amin N; Butterworth A; Chambers JC; Dedoussis G; Dehghan A; Franco OH; Franke L; Frontini M; Gambaro G; Gasparini P; Hamsten A; Issacs A; Kooner JS; Kooperberg C; Langenberg C; Marz W; Scott RA; Swertz MA; Toniolo D; Uitterlinden AG; van Duijn CM; Watkins H; Zeggini E; Maurano MT; Timpson NJ; Reiner AP; Auer PL; Soranzo N
Article: SCIENTIFIC REPORTS. 2016;6:35278
No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis
Loley C; Alver M; Assimes TL; Bjonnes A; Goel A; Gustafsson S; Hernesniemi J; Hopewell JC; Kanoni S; Kleber ME; Lau KW; Lu Y; Lyytikainen L-P; Nelson CP; Nikpay M; Qu L; Salfati E; Scholz M; Tukiainen T; Willenborg C; Won H-H; Zeng L; Zhang W; Anand SS; Beutner F; Bottinger EP; Clarke R; Dedoussis G; Do R; Esko T; Eskola M; Farrall M; Gauguier D; Giedraitis V; Granger CB; Hall AS; Hamsten A; Hazen SL; Huang J; Kahonen M; Kyriakou T; Laaksonen R; Lind L; Lindgren C; Magnusson PKE; Marouli E; Mihailov E; Morris AP; Nikus K; Pedersen N; Rallidis L; Salomaa V; Shah SH; Stewart AFR; Thompson JR; Zalloua PA; Chambers JC; Collins R; Ingelsson E; Iribarren C; Karhunen PJ; Kooner JS; Lehtimaki T; Loos RJF; Maerz W; McPherson R; Metspalu A; Reilly MP; Ripatti S; Sanghera DK; Thiery J; Watkins H; Deloukas P; Kathiresan S; Samani NJ; Schunkert H; Erdmann J; Koenig IR
Article: DIABETES. 2016;65(10):2888-2899
Soluble CD93 Is Involved in Metabolic Dysregulation but Does Not Influence Carotid Intima-Media Thickness
Strawbridge RJ; Hilding A; Silveira A; Osterholm C; Sennblad B; McLeod O; Tsikrika P; Foroogh F; Tremoli E; Baldassarre D; Veglia F; Rauramaa R; Smit AJ; Giral P; Kurl S; Mannarino E; Grossi E; Syvanen A-C; Humphries SE; de Faire U; Ostenson C-G; Maegdefessel L; Hamsten A; Backlund A
Article: NATURE GENETICS. 2016;48(10):1171-1184
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals
Ehret GB; Ferreira T; Chasman DI; Jackson AU; Schmidt EM; Johnson T; Thorleifsson G; Luan J; Donnelly LA; Kanoni S; Petersen A-K; Pihurl V; Strawbridge RJ; Shungin D; Hughes MF; Meirelles O; Kaakinen M; Bouatia-Naji N; Kristiansson K; Shah S; Kleber ME; Guo X; Lyytikainen L-P; Fava C; Eriksson N; Nolte IM; Magnusson PK; Salfati EL; Rallidis LS; Theusch E; Smith AJP; Folkersen L; Witkowska K; Pers TH; Joehanes R; Kim SK; Lataniotis L; Jansen R; Johnson AD; Warren H; Kim YJ; Zhao W; Wu Y; Tayo BO; Bochud M; Absher D; Adair LS; Amin N; Arkingl DE; Axelsson T; Baldassarre D; Balkau B; Bandinelli S; Barnes MR; Barroso I; Bevan S; Bis JC; Bjornsdottir G; Boehnke M; Boerwinkle E; Bonnycastle LL; Boomsma DI; Bornstein SR; Brown MJ; Burnier M; Cabrera CP; Chambers JC; Chang I-S; Cheng C-Y; Chines PS; Chung R-H; Collins FS; Connell JM; Doring A; Dallongeville J; Danesh J; de Faire U; Delgado G; Dominiczak AF; Doney ASF; Drenos F; Edkins S; Eicher JD; Elosua R; Enroth S; Erdmann J; Eriksson P; Esko T; Evangelou E; Evans A; Fai T; Farra M; Felixl JF; Ferrieres J; Ferrucci L; Fornage M; Forrester T; Franceschinil N; Franco OH; Franco-Cereceda A; Fraser RM; Ganesh SK; Gao H; Gertow K; Gianfagna F; Gigante B; Giulianini F; Goe A; Goodall AH; Goodarzi M; Gorski M; Grassler J; Groves CJ; Gudnason V; Gyllensten U; Hallmans G; Hartikainen A-L; Hassinen M; Havulinna AS; Hayward C; Hercberg S; Herzig K-H; Hicks AA; Hingorani AD; Hirschhorn JN; Hofmanl A; Holmen J; Holmen OL; Hottenga J-J; Howard P; Hsiung CA; Hunt SC; Ikram MA; Illig T; Iribarren C; Jensen RA; Kahonen M; Kang HM; Kathiresan S; Keating BJ; Khaw K-T; Kim YK; Kim E; Kivimaki M; Klopp N; Kolovou G; Komulainen P; Kooner JS; Kosova G; Krauss RM; Kuh D; Kutalik Z; Kuusisto J; Kvaloy K; Lakka TA; Lee NR; Lee I-T; Lee W-J; Levy D; Li X; Liang K-W; Lin H; Lin L; Lindstrom J; Lobbens S; Mannisto S; Muller G; Muller-Nurasyid M; Mach F; Markus HS; Marouli E; McCarthy MI; McKenzie CA; Meneton P; Menni C; Metspalu A; Mijatovic V; Moilanen L; Montasser ME; Morris AD; Morrison AC; Mulas A; Nagaraja R; Narisu N; Nikus K; O'Donnell CJ; O'Reilly PF; Ong KK; Paccaud F; Palmer CD; Parsa A; Pedersen NL; Penninx BW; Perola M; Peters A; Poulter N; Pramstaller PP; Psaty BM; Quertermous T; Rao DC; Rasheed A; Rayner NW; Renstrom F; Rettig R; Rice KM; Roberts R; Rose LM; Rossouw J; Samani NJ; Sanna S; Saramies J; Schunkert H; Sebert S; Sheu WH-H; Shin Y-A; Sim X; Smit JH; Smith AV; Sosa MX; Spector TD; Stancakova A; Stanton AV; Stirrups KE; Stringham HM; Sundstrom J; Swift AJ; Syvanen A-C; Tai E-S; Tanaka T; Tarasov KV; Teumer A; Thorsteinsdottir U; Tobin MD; Tremoli E; Uitterlinden AG; Uusitupa M; Vaez A; Vaidya D; van Duijn CM; van Iperen EPA; Vasan RS; Verwoert GC; Virtamo J; Vitart V; Voight BF; Vollenweider P; Wagner A; Wain LV; Wareham NJ; Watldns H; Weder AB; Westra HJ; Wilks R; Wilsgaard T; Wilson JF; Wong TY; Yang T-P; Yao J; Yengo L; Zhang W; Zhao JH; Zhu X; Bovet P; Cooper RS; Mohlke KL; Saleheen D; Lee J-Y; Elliott P; Gierman HJ; Willer CJ; Franke L; Hovingh GK; Taylor KD; Dedoussis G; Sever P; Wong A; Lind L; Assimes TL; Njolstad I; Schwarz PEH; Langenberg C; Snieder H; Caulfield MJ; Melander E; Laakso M; Saltevo J; Rauramaa R; Tuomilehto J; Ingelsson E; Lehtimaki T; Hveem K; Palmas W; Marz W; Kumar M; Salomaa V; Chen Y-DI; Rotter JI; Froguel P; Jarvelin M-R; Lakatta EG; Kuulasmaa K; Franks PW; Hamsten A; Wichmann H-E; Palmer CNA; Stefansson K; Ridker PM; Loos RJF; Chalcravarti A; Deloukas P; Morris AP; Newton-Cheh C; Munroe PB
Article: HUMAN MOLECULAR GENETICS. 2016;25(18):4094-4106
Analysis with the exome array identifies multiple new independent variants in lipid loci
Kanoni S; Masca NGD; Stirrups KE; Varga TV; Warren HR; Scott RA; Southam L; Zhang W; Yaghootkar H; Mueller-Nurasyid M; Alves AC; Strawbridge RJ; Lataniotis L; Hashim NA; Besse C; Boland A; Braund PS; Connell JM; Dominiczak A; Farmaki A-E; Franks S; Grallert H; Jansson J-H; Karaleftheri M; Keinanen-Kiukaanniemi S; Matchan A; Pasko D; Peters A; Poulter N; Rayner NW; Renstrom F; Rolandsson O; Sabater-Lleal M; Sennblad B; Sever P; Shields D; Silveira A; Stanton AV; Strauch K; Tomaszewski M; Tsafantakis E; Waldenberger M; Blakemore AIF; Dedoussis G; Escher SA; Kooner JS; McCarthy MI; Palmer CNA; Hamsten A; Caulfield MJ; Frayling TM; Tobin MD; Jarvelin M-R; Zeggini E; Gieger C; Chambers JC; Wareham NJ; Munroe PB; Franks PW; Samani NJ; Deloukas P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2016;36(9):1947-1961
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM
Matic LP; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Rohl S; Kronqvist M; Aldi S; Magne J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojevic V; Lehtio J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: HUMAN MOLECULAR GENETICS. 2016;25(9):1867-1874
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis
Hinds DA; Buil A; Ziemek D; Martinez-Perez A; Malik R; Folkersen L; Germain M; Malarstig A; Brown A; Manuel Soria J; Dichgans M; Bing N; Franco-Cereceda A; Carlos Souto J; Dermitzakis ET; Hamsten A; Worrall BB; Tung JY; Sabater-Lleal M
Article: CYTOKINE. 2016;81:1-9
Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease
McLeod O; Silveira A; Valdes-Marquez E; Bjorkbacka H; Almgren P; Gertow K; Gadin JR; Backlund A; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Tremoli E; de Faire U; Nilsson J; Melander O; Hopewell JC; Clarke R; Bjorck HM; Hamsten A; Ohrvik J; Strawbridge RJ
Article: CIRCULATION. 2016;133(13):1230-1239
Circulating Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Predicts Future Risk of Cardiovascular Events Independently of Established Risk Factors
Leander K; Malarstig A; van't Hooft FM; Hyde C; Hellenius M-L; Troutt JS; Konrad RJ; Ohrvik J; Hamsten A; de Faire U
Article: SCIENTIFIC REPORTS. 2016;6:21134
GeneiASE: Detection of condition-dependent and static allele-specific expression from RNA-seq data without haplotype information
Edsgard D; Iglesias MJ; Reilly S-J; Hamsten A; Tornvall P; Odeberg J; Emanuelsson O
Article: HUMAN MOLECULAR GENETICS. 2016;25(2):358-370
A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration
de Vries PS; Chasman DI; Sabater-Lleal M; Chen M-H; Huffman JE; Steri M; Tang W; Teumer A; Marioni RE; Grossmann V; Hottenga JJ; Trompet S; Mueller-Nurasyid M; Zhao JH; Brody JA; Kleber ME; Guo X; Wang JJ; Auer PL; Attia JR; Yanek LR; Ahluwalia TS; Lahti J; Venturini C; Tanaka T; Bielak LF; Joshi PK; Rocanin-Arjo A; Kolcic I; Navarro P; Rose LM; Oldmeadow C; Riess H; Mazur J; Basu S; Goel A; Yang Q; Ghanbari M; Willemsen G; Rumley A; Fiorillo E; de Craen AJM; Grotevendt A; Scott R; Taylor KD; Delgado GE; Yao J; Kifley A; Kooperberg C; Qayyum R; Lopez LM; Berentzen TL; Raikkonen K; Mangino M; Bandinelli S; Peyser PA; Wild S; Tregouet D-A; Wright AF; Marten J; Zemunik T; Morrison AC; Sennblad B; Tofler G; de Maat MPM; de Geus EJC; Lowe GD; Zoledziewska M; Sattar N; Binder H; Voelker U; Waldenberger M; Khaw K-T; Mcknight B; Huang J; Jenny NS; Holliday EG; Qi L; Mcevoy MG; Becker DM; Starr JM; Sarin A-P; Hysi PG; Hernandez DG; Jhun MA; Campbell H; Hamsten A; Rivadeneira F; Mcardle WL; Slagboom PE; Zeller T; Koenig W; Psaty BM; Haritunians T; Liu J; Palotie A; Uitterlinden AG; Stott DJ; Hofman A; Franco OH; Polasek O; Rudan I; Morange P-E; Wilson JF; Kardia SLR; Ferrucci L; Spector TD; Eriksson JG; Hansen T; Deary IJ; Becker LC; Scott RJ; Mitchell P; Maerz W; Wareham NJ; Peters A; Greinacher A; Wild PS; Jukema JW; Boomsma DI; Hayward C; Cucca F; Tracy R; Watkins H; Reiner AP; Folsom AR; Ridker PM; O'Donnell CJ; Smith NL; Strachan DP; Dehghan A
Article: PLOS ONE. 2016;11(1):e0146922
Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project
Martin-Fernandez L; Ziyatdinov A; Carrasco M; Antonio Millon J; Martinez-Perez A; Vilalta N; Brunel H; Font M; Hamsten A; Carlos Souto J; Manuel Soria J
Article: PLOS ONE. 2016;11(4):e0153990
Effects of Genetic Loci Associated with Central Obesity on Adipocyte Lipolysis
Strawbridge RJ; Laumen H; Hamsten A; Breier M; Grallert H; Hauner H; Arner P; Dahlman I
Article: THROMBOSIS AND HAEMOSTASIS. 2016;115(2):406-414
F11 is associated with recurrent VTE in women A prospective cohort study
Bruzelius M; Ljungqvist M; Bottai M; Bergendal A; Strawbridge RJ; Holmstrom M; Silveira A; Kieler H; Hamsten A; Larfars G; Odeberg J
Article: HUMAN MOLECULAR GENETICS. 2015;24(25):7445-7449
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index
Yang J; Bakshi A; Zhu Z; Hemani G; Vinkhuyzen AAE; Nolte IM; van Vliet-Ostaptchouk JV; Snieder H; Study LC; Esko T; Milani L; Maegi R; Metspalu A; Hamsten A; Magnusson PKE; Pedersen NL; Ingelsson E; Visscher PM
Article: NATURE GENETICS. 2015;47(12):1415-1425
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
Gaulton KJ; Ferreira T; Lee Y; Raimondo A; Maegi R; Reschen ME; Mahajan A; Locke A; Rayner NW; Robertson N; Scott RA; Prokopenko I; Scott LJ; Green T; Sparso T; Thuillier D; Yengo L; Grallert H; Wahl S; Franberg M; Strawbridge RJ; Kestler H; Chheda H; Eisele L; Gustafsson S; Steinthorsdottir V; Thorleifsson G; Qi L; Karssen LC; van Leeuwen EM; Willems SM; Li M; Chen H; Fuchsberger C; Kwan P; Ma C; Linderman M; Lu Y; Thomsen SK; Rundle JK; Beer NL; van de Bunt M; Chalisey A; Kang HM; Voight BF; Abecasis GR; Almgren P; Baldassarre D; Balkau B; Benediktsson R; Blueher M; Boeing H; Bonnycastle LL; Bottinger EP; Burtt NP; Carey J; Charpentier G; Chines PS; Cornelis MC; Couper DJ; Crenshaw AT; van Dam RM; Doney ASF; Dorkhan M; Edkins S; Eriksson JG; Esko T; Eury E; Fadista J; Flannick J; Fontanillas P; Fox C; Franks PW; Gertow K; Gieger C; Gigante B; Gottesman O; Grant GB; Grarup N; Groves CJ; Hassinen M; Have CT; Herder C; Holmen OL; Hreidarsson AB; Humphries SE; Hunter DJ; Jackson AU; Jonsson A; Jorgensen ME; Jorgensen T; Kao W-HL; Kerrison ND; Kinnunen L; Klopp N; Kong A; Kovacs P; Kraft P; Kravic J; Langford C; Leander K; Liang L; Lichtner P; Lindgren CM; Lindholm E; Linneberg A; Liu C-T; Lobbens S; Luan J; Lyssenko V; Mannisto S; McLeod O; Meyer J; Mihailov E; Mirza G; Muehleisen TW; Mueller-Nurasyid M; Navarro C; Noethen MM; Oskolkov NN; Owen KR; Palli D; Pechlivanis S; Peltonen L; Perry JRB; Platou CGP; Roden M; Ruderfer D; Rybin D; van der Schouw YT; Sennblad B; Sigurdsson G; Stancakova A; Steinbach G; Storm P; Strauch K; Stringham HM; Sun Q; Thorand B; Tikkanen E; Tonjes A; Trakalo J; Tremoli E; Tuomi T; Wennauer R; Wiltshire S; Wood AR; Zeggini E; Dunham I; Birney E; Pasquali L; Ferrer J; Loos RJF; Dupuis J; Florez JC; Boerwinkle E; Pankow JS; van Duijn C; Sijbrands E; Meigs JB; Hu FB; Thorsteinsdottir U; Stefansson K; Lakka TA; Rauramaa R; Stumvoll M; Pedersen NL; Lind L; Keinanen-Kiukaanniemi SM; Korpi-Hyovalti E; Saaristo TE; Saltevo J; Kuusisto J; Laakso M; Metspalu A; Erbel R; Joecke K-H; Moebus S; Ripatti S; Salomaa V; Ingelsson E; Boehm BO; Bergman RN; Collins FS; Mohlke KL; Koistinen H; Tuomilehto J; Hveem K; Njolstad I; Deloukas P; Donnelly PJ; Frayling TM; Hattersley AT; de Faire U; Hamsten A; Illig T; Peters A; Cauchi S; Sladek R; Froguel P; Hansen T; Pedersen O; Morris AD; Palmer CNA; Kathiresan S; Melander O; Nilsson PM; Groop LC; Barroso I; Langenberg C; Wareham NJ; O'Callaghan CA; Gloyn AL; Altshuler D; Boehnke M; Teslovich TM; McCarthy MI; Morris AP
Article: DIABETES. 2015;64(10):3425-3438
Toll-Like Receptor 3 Influences Glucose Homeostasis and β-Cell Insulin Secretion
Strodthoff D; Ma Z; Wirstrom T; Strawbridge RJ; Ketelhuth DFJ; Engel D; Clarke R; Falkmer S; Hamsten A; Hansson GK; Bjorklund A; Lundberg AM
Article: PLOS GENETICS. 2015;11(10):e1005378
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Winkler TW; Justice AE; Graff M; Barata L; Feitosa MF; Chu S; Czajkowski J; Esko T; Fall T; Kilpelainen TO; Lu Y; Magi R; Mihailov E; Pers TH; Rueeger S; Teumer A; Ehret GB; Ferreira T; Heard-Costa NL; Karjalainen J; Lagou V; Mahajan A; Neinast MD; Prokopenko I; Simino J; Teslovich TM; Jansen R; Westra H-J; White CC; Absher D; Ahluwalia TS; Ahmad S; Albrecht E; Alves AC; Bragg-Gresham JL; de Craen AJM; Bis JC; Bonnefond A; Boucher G; Cadby G; Cheng Y-C; Chiang CWK; Delgado G; Demirkan A; Dueker N; Eklund N; Eiriksdottir G; Eriksson J; Feenstra B; Fischer K; Frau F; Galesloot TE; Geller F; Goel A; Gorski M; Grammer TB; Gustafsson S; Haitjema S; Hottenga J-J; Huffman JE; Jackson AU; Jacobs KB; Johansson A; Kaakinen M; Kleber ME; Lahti J; Leach IM; Lehne B; Liu Y; Lo KS; Lorentzon M; Luan J; Madden PAF; Mangino M; McKnight B; Medina-Gomez C; Monda KL; Montasser ME; Mueller G; Mueller-Nurasyid M; Nolte IM; Panoutsopoulou K; Pascoe L; Paternoster L; Rayner NW; Renstrom F; Rizzi F; Rose LM; Ryan KA; Salo P; Sanna S; Scharnagl H; Shi J; Smith AV; Southam L; Stancakova A; Steinthorsdottir V; Strawbridge RJ; Sung YJ; Tachmazidou I; Tanaka T; Thorleifsson G; Trompet S; Pervjakova N; Tyrer JP; Vandenput L; van der Laan SW; van der Velde N; van Setten J; van Vliet-Ostaptchouk JV; Verweij N; Vlachopoulou E; Waite LL; Wang SR; Wang Z; Wild SH; Willenborg C; Wilson JF; Wong A; Yang J; Yengo L; Yerges-Armstrong LM; Yu L; Zhang W; Zhao JH; Andersson EA; Bakker SJL; Baldassarre D; Banasik K; Barcella M; Barlassina C; Bellis C; Benaglio P; Blangero J; Blueher M; Bonnet F; Bonnycastle LL; Boyd HA; Bruinenberg M; Buchman AS; Campbell H; Chen Y-DI; Chines PS; Claudi-Boehm S; Cole J; Collins FS; de Geus EJC; de Groot LCPGM; Dimitriou M; Duan J; Enroth S; Eury E; Farmaki A-E; Forouhi NG; Friedrich N; Gejman PV; Gigante B; Glorioso N; Go AS; Gottesman O; Graessler J; Grallert H; Grarup N; Gu Y-M; Broer L; Ham AC; Hansen T; Harris TB; Hartman CA; Hassinen M; Hastie N; Hattersley AT; Heath AC; Henders AK; Hernandez D; Hillege H; Holmen O; Hovingh KG; Hui J; Husemoen LL; Hutri-Kahonen N; Hysi PG; Illig T; De Jager PL; Jalilzadeh S; Jorgensen T; Jukema JW; Juonala M; Kanoni S; Karaleftheri M; Khaw KT; Kinnunen L; Kittner SJ; Koenig W; Kolcic I; Kovacs P; Krarup NT; Kratzer W; Krueger J; Kuh D; Kumari M; Kyriakou T; Langenberg C; Lannfelt L; Lanzani C; Lotay V; Launer LJ; Leander K; Lindstrom J; Linneberg A; Liu Y-P; Lobbens S; Luben R; Lyssenko V; Mannisto S; Magnusson PK; McArdle WL; Menni C; Merger S; Milani L; Montgomery GW; Morris AP; Narisu N; Nelis M; Ong KK; Palotie A; Perusse L; Pichler I; Pilia MG; Pouta A; Rheinberger M; Ribel-Madsen R; Richards M; Rice KM; Rice TK; Rivolta C; Salomaa V; Sanders AR; Sarzynski MA; Scholtens S; Scott RA; Scott WR; Sebert S; Sengupta S; Sennblad B; Seufferlein T; Silveira A; Slagboom PE; Smit JH; Sparso TH; Stirrups K; Stolk RP; Stringham HM; Swertz MA; Swift AJ; Syvanen A-C; Tan S-T; Thorand B; Toenjes A; Tremblay A; Tsafantakis E; van der Most PJ; Voelker U; Vohl M-C; Vonk JM; Waldenberger M; Walker RW; Wennauer R; Widen E; Willemsen G; Wilsgaard T; Wright AF; Zillikens MC; van Dijk SC; van Schoor NM; Asselbergs FW; de Bakker PIW; Beckmann JS; Beilby J; Bennett DA; Bergman RN; Bergmann S; Boeger CA; Boehm BO; Boerwinkle E; Boomsma DI; Bornstein SR; Bottinger EP; Bouchard C; Chambers JC; Chanock SJ; Chasman DI; Cucca F; Cusi D; Dedoussis G; Erdmann J; Eriksson JG; Evans DA; de Faire U; Farrall M; Ferrucci L; Ford I; Franke L; Franks PW; Froguel P; Gansevoort RT; Gieger C; Gronberg H; Gudnason V; Gyllensten U; Hall P; Hamsten A; van der Harst P; Hayward C; Heliovaara M; Hengstenberg C; Hicks AA; Hingorani A; Hofman A; Hu F; Huikuri HV; Hveem K; James AL; Jordan JM; Jula A; Kaehoenen M; Kajantie E; Kathiresan S; Kiemeney LALM; Kivimaki M; Knekt PB; Koistinen HA; Kooner JS; Koskinen S; Kuusisto J; Maerz W; Martin NG; Laakso M; Lakka TA; Lehtimaki T; Lettre G; Levinson DF; Lind L; Lokki M-L; Mantyselka P; Melbye M; Metspalu A; Mitchell BD; Moll FL; Murray JC; Musk AW; Nieminen MS; Njolstad I; Ohlsson C; Oldehinkel AJ; Oostra BA; Palmer LJ; Pankow JS; Pasterkamp G; Pedersen NL; Pedersen O; Penninx BW; Perola M; Peters A; Polasek O; Pramstaller PP; Psaty BM; Qi L; Quertermous T; Raitakari OT; Rankinen T; Rauramaa R; Ridker PM; Rioux JD; Rivadeneira F; Rotter JI; Rudan I; den Ruijter HM; Saltevo J; Sattar N; Schunkert H; Schwarz PEH; Shuldiner AR; Sinisalo J; Snieder H; Sorensen TIA; Spector TD; Staessen JA; Stefania B; Thorsteinsdottir U; Stumvoll M; Tardif J-C; Tremoli E; Tuomilehto J; Uitterlinden AG; Uusitupa M; Verbeek ALM; Vermeulen SH; Viikari JS; Vitart V; Voelzke H; Vollenweider P; Waeber G; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Zeggini E; Chakravarti A; Clegg DJ; Cupples LA; Gordon-Larsen P; Jaquish CE; Rao DC; Abecasis GR; Assimes TL; Barroso I; Berndt SI; Boehnke M; Deloukas P; Fox CS; Groop LC; Hunter DJ; Ingelsson E; Kaplan RC; McCarthy MI; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Hirschhorn JN; Lindgren CM; Heid IM; North KE; Borecki IB; Kutalik Z; Loos RJF
Article: NATURE GENETICS. 2015;47(10):1121-1130
A comprehensive 1000 Genomes-based genome-wide association meta-analysis of coronary artery disease
Nikpay M; Goel A; Won H-H; Hall LM; Willenborg C; Kanoni S; Saleheen D; Kyriakou T; Nelson CP; Hopewell JC; Webb TR; Zeng L; Dehghan A; Alver M; Armasu SM; Auro K; Bjonnes A; Chasman DI; Chen S; Ford I; Franceschini N; Gieger C; Grace C; Gustafsson S; Huang J; Hwang S-J; Kim YK; Kleber ME; Lau KW; Lu X; Lu Y; Lyytikainen L-P; Mihailov E; Morrison AC; Pervjakova N; Qu L; Rose LM; Salfati E; Saxena R; Scholz M; Smith AV; Tikkanen E; Uitterlinden A; Yang X; Zhang W; Zhao W; de Andrade M; de Vries PS; van Zuydam NR; Anand SS; Bertram L; Beutner F; Dedoussis G; Frossard P; Gauguier D; Goodall AH; Gottesman O; Haber M; Han B-G; Huang J; Jalilzadeh S; Kessler T; Koenig IR; Lannfelt L; Lieb W; Lind L; Lindgren CM; Lokki M-L; Magnusson PK; Mallick NH; Mehra N; Meitinger T; Memon F-U; Morris AP; Nieminen MS; Pedersen NL; Peters A; Rallidis LS; Rasheed A; Samuel M; Shah SH; Sinisalo J; Stirrups KE; Trompet S; Wang L; Zaman KS; Ardissino D; Boerwinkle E; Borecki IB; Bottinger EP; Buring JE; Chambers JC; Collins R; Cupples LA; Danesh J; Demuth I; Elosua R; Epstein SE; Esko T; Feitosa MF; Franco OH; Franzosi MG; Granger CB; Gu D; Gudnason V; Hall AS; Hamsten A; Harris TB; Hazen SL; Hengstenberg C; Hofman A; Ingelsson E; Iribarren C; Jukema JW; Karhunen PJ; Kim B-J; Kooner JS; Kullo IJ; Lehtimaki T; Loos RJF; Melander O; Metspalu A; Maerz W; Palmer CN; Perola M; Quertermous T; Rader DJ; Ridker PM; Ripatti S; Roberts R; Salomaa V; Sanghera DK; Schwartz SM; Seedorf U; Stewart AF; Stott DJ; Thiery J; Zalloua PA; O'Donnell CJ; Reilly MP; Assimes TL; Thompson JR; Erdmann J; Clarke R; Watkins H; Kathiresan S; McPherson R; Deloukas P; Schunkert H; Samani NJ; Farrall M
Article: NATURE GENETICS. 2015;47(10):1114-1120
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index
Yang J; Bakshi A; Zhu Z; Hemani G; Vinkhuyzen AAE; Lee SH; Robinson MR; Perry JRB; Nolte IM; van Vliet-Ostaptchouk JV; Snieder H; Esko T; Milani L; Maegi R; Metspalu A; Hamsten A; Magnusson PKE; Pedersen NL; Ingelsson E; Soranzo N; Keller MC; Wray NR; Goddard ME; Visscher PM
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2015;8(5):696-706
Functional Analysis of a Carotid Intima-Media Thickness Locus Implicates BCAR1 and Suggests a Causal Variant
Boardman-Pretty F; Smith AJP; Cooper J; Palmen J; Folkersen L; Hamsten A; Catapano AL; Melander O; Price JF; Kumari M; Deanfield JE; Kivimaki M; Gertow K; Baragetti A; Norata GD; Humphries SE
Article: BLOOD. 2015;126(11):e19-e29
Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF
Huffman JE; de Vries PS; Morrison AC; Sabater-Lleal M; Kacprowski T; Auer PL; Brody JA; Chasman DI; Chen M-H; Guo X; Lin L-A; Marioni RE; Mueller-Nurasyid M; Yanek LR; Pankratz N; Grove ML; de Maat MPM; Cushman M; Wiggins KL; Qi L; Sennblad B; Harris SE; Polasek O; Riess H; Rivadeneira F; Rose LM; Goel A; Taylor KD; Teumer A; Uitterlinden AG; Vaidya D; Yao J; Tang W; Levy D; Waldenberger M; Becker DM; Folsom AR; Giulianini F; Greinacher A; Hofman A; Huang C-C; Kooperberg C; Silveira A; Starr JM; Strauch K; Strawbridge RJ; Wright AF; McKnight B; Franco OH; Zakai N; Mathias RA; Psaty BM; Ridker PM; Tofler GH; Voelker U; Watkins H; Fornage M; Hamsten A; Deary IJ; Boerwinkle E; Koenig W; Rotter JI; Hayward C; Dehghan A; Reiner AP; O'Donnell CJ; Smith NL
Article: PLOS GENETICS. 2015;11(9):e1005502
Discovering Genetic Interactions in Large-Scale Association Studies by Stage-wise Likelihood Ratio Tests
Franberg M; Gertow K; Hamsten A; Lagergren J; Sennblad B
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2015;23(9):1216-1222
Exome sequencing followed by genotyping suggests SYPL2 as a susceptibility gene for morbid obesity
Jiao H; Arner P; Gerdhem P; Strawbridge RJ; Naslund E; Thorell A; Hamsten A; Kere J; Dahlman I
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2015;4(8):e001853
Sex-Specific Effects of Adiponectin on Carotid Intima-Media Thickness and Incident Cardiovascular Disease
Persson J; Strawbridge RJ; McLeod O; Gertow K; Silveira A; Baldassarre D; Van Zuydam N; Shah S; Fava C; Gustafsson S; Veglia F; Sennblad B; Larsson M; Sabater-Lleal M; Leander K; Gigante B; Tabak A; Kivimaki M; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Humphries SE; Tremoli E; de Faire U; Lind L; Ingelsson E; Hedblad B; Melander O; Kumari M; Hingorani A; Morris AD; Palmer CNA; Lundman P; Ohrvik J; Soderberg S
Article: NATURE. 2015;523(7561):459-U176
Directional dominance on stature and cognition in diverse human populations
Joshi PK; Esko T; Mattsson H; Eklund N; Gandin I; Nutile T; Jackson AU; Schurmann C; Smith AV; Zhang W; Okada Y; Stancakova A; Faul JD; Zhao W; Bartz TM; Concas MP; Franceschini N; Enroth S; Vitart V; Trompet S; Guo X; Chasman DI; O'Connel JR; Corre T; Nongmaithem SS; Chen Y; Mangino M; Ruggiero D; Traglia M; Farmaki A-E; Kacprowski T; Bjonnes A; van der Spek A; Wu Y; Giri AK; Yanek LR; Wang L; Hofer E; Rietveld CA; McLeod O; Cornelis MC; Pattaro C; Verweij N; Baumbach C; Abdellaoui A; Warren HR; Vuckovic D; Mei H; Bouchard C; Perry JRB; Cappellani S; Mirza SS; Benton MC; Broeckel U; Medland SE; Lind P; Malerba G; Drong A; Yengo L; Bielak LF; Zhi D; van der Most PJ; Shriner D; Maegi R; Hemani G; Karaderi T; Wang Z; Liu T; Demuth I; Zhao JH; Meng W; Lataniotis L; van der Laan SW; Bradfield JP; Wood AR; Bonnefond A; Ahluwalia TS; Hall L; Salvi E; Yazar S; Carstensen L; de Haan HG; Abney M; Afzal U; Allison MA; Amin N; Asselbergs FW; Bakker SJL; Barr RG; Baumeister SE; Benjamin DJ; Bergmann S; Boerwinkle E; Bottinger EP; Campbell A; Chakravarti A; Chan Y; Chanock SJ; Chen C; Chen Y-DI; Collins FS; Connell J; Correa A; Cupples LA; Smith GD; Davies G; Doerr M; Ehret G; Ellis SB; Feenstra B; Feitosa MF; Ford I; Fox CS; Frayling TM; Friedrich N; Geller F; Scotland G; Gillham-Nasenya I; Gottesman O; Graff M; Grodstein F; Gu C; Haley C; Hammond CJ; Harris SE; Harris TB; Hastie ND; Heard-Costa NL; Heikkila K; Hocking LJ; Homuth G; Hottenga J-J; Huang J; Huffman JE; Hysi PG; Ikram MA; Ingelsson E; Joensuu A; Johansson A; Jousilahti P; Jukema JW; Kahonen M; Kamatani Y; Kanoni S; Kerr SM; Khan NM; Koellinger P; Koistinen HA; Kooner MK; Kubo M; Kuusisto J; Lahti J; Launer LJ; Lea RA; Lehne B; Lehtimaki T; Liewald DCM; Lind L; Loh M; Lokki M-L; London SJ; Loomis SJ; Loukola A; Lu Y; Lumley T; Lundqvist A; Mannisto S; Marques-Vidal P; Masciullo C; Matchan A; Mathias RA; Matsuda K; Meigs JB; Meisinger C; Meitinger T; Menni C; Mentch FD; Mihailov E; Milani L; Montasser ME; Montgomery G; Morrison A; Myers RH; Nadukuru R; Navarro P; Nelis M; Nieminen MS; Nolte IM; O'Connor GT; Ogunniyi A; Padmanabhan S; Palmas WR; Pankow JS; Patarcic I; Pavani F; Peyser PA; Pietilainen K; Poulter N; Prokopenko I; Ralhan S; Redmond P; Rich SS; Rissanen H; Robino A; Rose LM; Rose R; Sala C; Salako B; Salomaa V; Sarin A-P; Saxena R; Schmidt H; Scott LJ; Scott WR; Sennblad B; Seshadri S; Sever P; Shrestha S; Smith BH; Smith JA; Soranzo N; Sotoodehnia N; Southam L; Stanton AV; Stathopoulou MG; Strauch K; Strawbridge RJ; Suderman MJ; Tandon N; Tang S-T; Taylor KD; Tayo BO; Toeglhofer AM; Tomaszewski M; Tsernikova N; Tuomilehto J; Uitterlinden AG; Vaidya D; Vlieg AVH; van Setten J; Vasankari T; Vedantam S; Vlachopoulou E; Vozzi D; Vuoksimaa E; Waldenberger M; Ware EB; Wentworth-Shields W; Whitfield JB; Wild S; Willemsen G; Yajnik CS; Yao J; Zaza G; Zhu X; Salem RM; Melbye M; Bisgaard H; Samani NJ; Cusi D; Mackey DA; Cooper RS; Froguel P; Pasterkamp G; Grant SFA; Hakonarson H; Ferrucci L; Scott RA; Morris AD; Palmer CNA; Dedoussis G; Deloukas P; Bertram L; Lindenberger U; Berndt SI; Lindgren CM; Timpson NJ; Toenjes A; Munroe PB; Sorensen TIA; Rotimi CN; Arnett DK; Oldehinkel AJ; Kardia SLR; Balkau B; Gambaro G; Morris AP; Eriksson JG; Wright MJ; Martin NG; Hunt SC; Starr JM; Deary IJ; Griffiths LR; Tiemeier H; Pirastu N; Kaprio J; Wareham NJ; Perusse L; Wilson JG; Girotto G; Caulfield MJ; Raitakari O; Boomsma DI; Gieger C; van der Harst P; Hicks AA; Kraft P; Sinisalo J; Knekt P; Johannesson M; Magnusson PKE; Hamsten A; Schmidt R; Borecki IB; Vartiainen E; Becker DM; Bharadwaj D; Mohlke KL; Boehnke M; van Duijn CM; Sanghera DK; Teumer A; Zeggini E; Metspalu A; Gasparini P; Ulivi S; Ober C; Toniolo D; Rudan I; Porteous DJ; Ciullo M; Spector TD; Hayward C; Dupuis J; Loos RJF; Wright AF; Chandak GR; Vollenweider P; Shuldiner AR; Ridker PM; Rotter JI; Sattar N; Gyllensten U; North KE; Pirastu M; Psaty BM; Weir DR; Laakso M; Gudnason V; Takahashi A; Chambers JC; Kooner JS; Strachan DP; Campbell H; Hirschhorn JN; Perola M; Polasek O; Wilson JF
Article: PLOS GENETICS. 2015;11(7):e1005230
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation
Horikoshi M; Maegi R; van de Bunt M; Surakka I; Sarin A-P; Mahajan A; Marullo L; Thorleifsson G; Haegg S; Hottenga J-J; Ladenvall C; Ried JS; Winkler TW; Willems SM; Pervjakova N; Esko T; Beekman M; Nelson CP; Willenborg C; Wiltshire S; Ferreira T; Fernandez J; Gaulton KJ; Steinthorsdottir V; Hamsten A; Magnusson PKE; Willemsen G; Milaneschi Y; Robertson NR; Groves CJ; Bennett AJ; Lehtimaeki T; Viikari JS; Rung J; Lyssenko V; Perola M; Heid IM; Herder C; Grallert H; Mueller-Nurasyid M; Roden M; Hypponen E; Isaacs A; van Leeuwen EM; Karssen LC; Mihailov E; Houwing-Duistermaat JJ; de Craen AJM; Deelen J; Havulinna AS; Blades M; Hengstenberg C; Erdmann J; Schunkert H; Kaprio J; Tobin MD; Samani NJ; Lind L; Salomaa V; Lindgren CM; Slagboom PE; Metspalu A; van Duijn CM; Eriksson JG; Peters A; Gieger C; Jula A; Groop L; Raitakari OT; Power C; Penninx BWJH; de Geus E; Smit JH; Boomsma DI; Pedersen NL; Ingelsson E; Thorsteinsdottir U; Stefansson K; Ripatti S; Prokopenko I; McCarthy MI; Morris AP
Article: NATURE GENETICS. 2015;47(6):589-597
The impact of low-frequency and rare variants on lipid levels
Surakka I; Horikoshi M; Magi R; Sarin A-P; Mahajan A; Lagou V; Marullo L; Ferreira T; Miraglio B; Timonen S; Kettunen J; Pirinen M; Karjalainen J; Thorleifsson G; Hagg S; Hottenga J-J; Isaacs A; Ladenvall C; Beekman M; Esko T; Ried JS; Nelson CP; Willenborg C; Gustafsson S; Westra H-J; Blades M; de Craen AJM; de Geus EJ; Deelen J; Grallert H; Hamsten A; Havulinna AS; Hengstenberg C; Houwing-Duistermaat JJ; Hypponen E; Karssen LC; Lehtimaki T; Lyssenko V; Magnusson PKE; Mihailov E; Muller-Nurasyid M; Mpindi J-P; Pedersen NL; Penninx BWJH; Perola M; Pers TH; Peters A; Rung J; Smit JH; Steinthorsdottir V; Tobin MD; Tsernikova N; van Leeuwen EM; Viikari JS; Willems SM; Willemsen G; Schunkert H; Erdmann J; Samani NJ; Kaprio J; Lind L; Gieger C; Metspalu A; Slagboom PE; Groop L; van Duijn CM; Eriksson JG; Jula A; Salomaa V; Boomsma DI; Power C; Raitakari OT; Ingelsson E; Jarvelin M-R; Thorsteinsdottir U; Franke L; Ikonen E; Kallioniemi O; Pietiainen V; Lindgren CM; Stefansson K; Palotie A; McCarthy MI; Morris AP; Prokopenko I; Ripatti S
Article: DIABETOLOGIA. 2015;58(6):1363-1371
Protein biomarkers for the prediction of cardiovascular disease in type 2 diabetes
Looker HC; Colombo M; Agakov F; Zeller T; Groop L; Thorand B; Palmer CN; Hamsten A; de Faire U; Nogoceke E; Livingstone SJ; Salomaa V; Leander K; Barbarini N; Bellazzi R; van Zuydam N; McKeigue PM; Colhoun HM
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2015;23(5):688-692
Identity-by-descent mapping in a Scandinavian multiple sclerosis cohort
Westerlind H; Imrell K; Ramanujam R; Myhr K-M; Celius EG; Harbo HF; Oturai AB; Hamsten A; Alfredsson L; Olsson T; Kockum I; Koski T; Hillert J
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2015;372(17):1608-1618
Genetically Determined Height and Coronary Artery Disease
Nelson CP; Hamby SE; Saleheen D; Hopewell JC; Zeng L; Assimes TL; Kanoni S; Willenborg C; Burgess S; Amouyel P; Anand S; Blankenberg S; Boehm BO; Clarke RJ; Collins R; Dedoussis G; Farrall M; Franks PW; Groop L; Hall AS; Hamsten A; Hengstenberg C; Hovingh GK; Ingelsson E; Kathiresan S; Kee F; Koenig IR; Kooner J; Lehtimaeki T; Maerz W; McPherson R; Metspalu A; Nieminen MS; O'Donnell CJ; Palmer CNA; Peters A; Perola M; Reilly MP; Ripatti S; Roberts R; Salomaa V; Shah SH; Schreiber S; Siegbahn A; Thorsteinsdottir U; Veronesi G; Wareham N; Willer CJ; Zalloua PA; Erdmann J; Deloukas P; Watkins H; Schunkert H; Danesh J; Thompson JR; Samani NJ
Article: OBESITY REVIEWS. 2015;16(4):327-340
Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults
Zimmermann E; Angquist LH; Mirza SS; Zhao JH; Chasman DI; Fischer K; Qi Q; Smith AV; Thinggaard M; Jarczok MN; Nalls MA; Trompet S; Timpson NJ; Schmidt B; Jackson AU; Lyytikainen LP; Verweij N; Mueller-Nurasyid M; Vikstrom M; Marques-Vidal P; Wong A; Meidtner K; Middelberg RP; Strawbridge RJ; Christiansen L; Kyvik KO; Hamsten A; Jaaskelainen T; Tjonneland A; Eriksson JG; Whitfield JB; Boeing H; Hardy R; Vollenweider P; Leander K; Peters A; van der Harst P; Kumari M; Lehtimaki T; Meirhaeghe A; Tuomilehto J; Joeckel K-H; Ben-Shlomo Y; Sattar N; Baumeister SE; Smith GD; Casas JP; Houston DK; Maerz W; Christensen K; Gudnason V; Hu FB; Metspalu A; Ridker PM; Wareham NJ; Loos RJF; Tiemeier H; Sonestedt E; Sorensen TIA
Article: ATHEROSCLEROSIS. 2015;239(2):304-310
GWAS-identified loci for coronary heart disease are associated with intima-media thickness and plaque presence at the carotid artery bulb
den Hoed M; Strawbridge RJ; Almgren P; Gustafsson S; Axelsson T; Engstrom G; de Faire U; Hedblad B; Humphries SE; Lindgren CM; Morris AP; Ostling G; Syvanen A-C; Tremoli E; Hamsten A; Ingelsson E; Melander O; Lind L
Article: CYTOKINE. 2015;72(2):178-184
Duffy antigen receptor genetic variant and the association with Interleukin 8 levels
Velasquez IM; Kumar J; Bjorkbacka H; Nilsson J; Silveira A; Leander K; Berglund A; Strawbridge RJ; Arnlov J; Melander O; Almgren P; Lind L; Hamsten A; de Faire U; Gigante B
Article: ATHEROSCLEROSIS. 2015;239(1):125-130
Plasma IL-5 concentration and subclinical carotid atherosclerosis
Silveira A; McLeod O; Strawbridge RJ; Gertow K; Sennblad B; Baldassarre D; Veglia F; Deleskog A; Persson J; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Gustafsson S; Soderberg S; Ohrvik J; Humphries SE; Tremoli E; de Faire U; Hamsten A
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY: HEART & VASCULATURE. 2015;6:42-47
Autoantibodies against basement membrane collagen type IV are associated with myocardial infarction.
McLeod O; Dunér P; Samnegård A; Tornvall P; Nilsson J; Hamsten A; Bengtsson E
Article: CIRCULATION RESEARCH. 2015;116(4):642-652
Increased Arterial Blood Pressure and Vascular Remodeling in Mice Lacking Salt-Inducible Kinase 1 (SIK1)
Bertorello AM; Pires N; Igreja B; Pinho MJ; Vorkapic E; Wagsater D; Wikstrom J; Behrendt M; Hamsten A; Eriksson P; Soares-da-Silva P; Brion L
Article: NATURE. 2015;518(7538):197-206
Genetic studies of body mass index yield new insights for obesity biology
Locke AE; Kahali B; Berndt SI; Justice AE; Pers TH; Day FR; Powell C; Vedantam S; Buchkovich ML; Yang J; Croteau-Chonka DC; Esko T; Fall T; Ferreira T; Gustafsson S; Kutalik Z; Luan J; Maegi R; Randall JC; Winkler TW; Wood AR; Workalemahu T; Faul JD; Smith JA; Zhao JH; Zhao W; Chen J; Fehrmann R; Hedman AK; Karjalainen J; Schmidt EM; Absher D; Amin N; Anderson D; Beekman M; Bolton JL; Bragg-Gresham L; Buyske S; Demirkan A; Deng G; Ehret GB; Feenstra B; Feitosa MF; Fischer K; Goel A; Gong J; Jackson AU; Kanoni S; Kleber ME; Kristiansson K; Lim U; Lotay V; Mangino M; Leach IM; Medina-Gomez C; Medland SE; Nalls MA; Palmer CD; Pasko D; Pechlivanis S; Peters MJ; Prokopenko I; Shungin D; Stancakova A; Strawbridge RJ; Sung YJ; Tanaka T; Teumer A; Trompet S; van der Laan SW; van Settee J; Van Vliet-Ostaptchouk JV; Wang Z; Yengo L; Zhang W; Isaacs A; Albrecht E; Arnlov J; Arscott GM; Attwood AP; Bandinelli S; Barrett A; Bas IN; Bellis C; Bennett AJ; Berne C; Blagieva R; Blueher M; Bohringer S; Bonnycastle LL; Boettcher Y; Boyd HA; Bruinenberg M; Caspersen IH; Chen Y-DI; Clarke R; Daw EW; de Craen AJM; Delgado G; Dimitriou M; Doney ASF; Eklund N; Estrada K; Eury E; Folkersen L; Fraser RM; Garcia ME; Geller F; Giedraitis V; Gigante B; Go AS; Golay A; Goodall AH; Gordon SD; Gorski M; Grabe H-J; Grallert H; Grammer TB; Graessler J; Gronberg H; Groves CJ; Gusto G; Haessler J; Hall P; Haller T; Hallmans G; Hartman CA; Hassinen M; Hayward C; Heard-Costa NL; Helmer Q; Hengstenberg C; Holmen O; Hottenga J-J; James AL; Jeff JM; Johansson A; Jolley J; Juliusdottir T; Kinnunen L; Koenig W; Koskenvuo M; Kratzer W; Laitinen J; Lamina C; Leander K; Lee NR; Lichtner P; Lind L; Lindstrom J; Lo KS; Lobbens S; Lorbeer R; Lu Y; Mach F; Magnusson PKE; Mahajan A; McArdle WL; McLachlan S; Menni C; Merger S; Mihailov E; Milani L; Moayyeri A; Monda KL; Morken MA; Mulas A; Mueller G; Mueller-Nurasyid M; Musk AW; Nagaraja R; Noethen MM; Nolte IM; Pilz S; Rayner NW; Renstrom F; Rettig R; Ried JS; Ripke S; Robertson NR; Rose LM; Sanna S; Scharnagl H; Scholtens S; Schumacher FR; Scott WR; Seufferlein T; Shi J; Smith AV; Smolonska J; Stanton AV; Steinthorsdottir V; Stirrups K; Stringham HM; Sundstrom J; Swertz MA; Swift AJ; Syvanen A-C; Tan S-T; Tayo BO; Thorand B; Thorleifsson G; Tyrer JP; Uh H-W; Vandenput L; Verhulst FC; Vermeulen SH; Verweij N; Vonk JM; Waite LL; Warren HR; Waterworth D; Weedon MN; Wilkens LR; Willenborg C; Wilsgaard T; Wojczynski MK; Wong A; Wrightl AF; Zhang Q; Brennan EP; Choi M; Dastani Z; Drong AW; Eriksson P; Franco-Cereceda A; Gadin JR; Gharavi AG; Goddard ME; Handsaker RE; Huang J; Karpe F; Kathiresan S; Keildson S; Kiryluk K; Kubo M; Lee J-Y; Liang L; Lifton RP; Ma B; McCarroll SA; McKnight AJ; Min JL; Moffatt MF; Montgomery GW; Murabito JM; Nicholson G; Nyholt DR; Okada Y; Perry JRB; Dorajoo R; Reinmaa E; Salem RM; Sandholm N; Scott RA; Stolk L; Takahashi A; Tanaka T; van 't Hooft FM; Vinkhuyzen AAE; Westra H-J; Zheng W; Zondervan KT; Heath AC; Arveiler D; Bakker SJL; Beilby J; Bergman RN; Blangero J; Bovet P; Campbell H; Caulfield MJ; Cesana G; Chakravarti A; Chasman DI; Chines PS; Collins FS; Crawford DC; Cupples LA; Cusi D; Danesh J; de Faire U; den Ruijter HM; Dominiczak AF; Erbel R; Erdmann J; Eriksson JG; Farrall M; Felix SB; Ferrannini E; Ferrieres J; Ford I; Forouhi NG; Forrester T; Franco OH; Gansevoort RT; Gejman PV; Gieger C; Gottesman O; Gudnason V; Gyllensten U; Hall AS; Harris TB; Hattersley AT; Hicks AA; Hindorff LA; Hingorani AD; Hofman A; Homuth G; Hovingh GK; Humphries SE; Hunt SC; Hypponen E; Illig T; Jacobs KB; Jarvelin M-R; Joeckel K-H; Johansen B; Jousilahti P; Jukema JW; Jula AM; Kaprio J; Kastelein JJP; Keinanen-Kiukaanniemi SM; Kiemeney LA; Knekt P; Kooner JS; Kooperberg C; Kovacs P; Kraja AT; Kumari M; Kuusisto J; Lakka TA; Langenberg C; Le Marchand L; Lehtimaki T; Lyssenko V; Mannisto S; Marette A; Matise TC; McKenzie CA; McKnight B; Moll FL; Morris AD; Morris AP; Murray JC; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Madden PAF; Pasterkamp G; Peden JF; Peters A; Postma DS; Pramstaller PP; Price JF; Qi L; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ridker PM; Rioux JD; Ritchie MD; Rudan I; Salomaa V; Samani NJ; Saramines J; Sarzynski MA; Schunkert H; Schwarz PEH; Sever P; Shuldiner AR; Sinisalo J; Stolk RP; Strauch K; Toenjes A; Tregouet D-A; Tremblay A; Tremoli E; Virtamo J; Vohl M-C; Voelker U; Waeber G; Willemsen G; Witteman JC; Zillikens MC; Adair LS; Amouyel P; Asselbergs FW; Assimes TL; Bochud M; Boehm BO; Boerwinkle E; Bornstein SR; Bottinger EP; Bouchard C; Cauchi S; Chambers JC; Chanock SJ; Cooper RS; de Bakker PIW; Dedoussis G; Ferrucci L; Franks PW; Froguel P; Groop LC; Haiman CA; Hamsten A; Hui J; Hunter DJ; Hveem K; Kaplan RC; Kivimaki M; Kuh D; Laakso M; Liu Y; Martin NG; Maerz W; Melbve M; Metspalu A; Moebus S; Munroe PB; Njolstad I; Oostra BA; Palmer CNA; Pedersen NL; Perola M; Perusse L; Peters U; Power C; Quertermous T; Rauramaa R; Rivadeneira F; Saaristo TE; Saleheen D; Sattar N; Schadt EE; Schlessinger D; Slagboom PE; Snieder H; Spector TD; Thorsteinsdottir UR; Stumvoll M; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Weir DR; Wichmann H-E; Wilson JF; Zanen P; Borecki IB; Deloukas P; Fox CS; Heid IM; O'Connell JR; Strachan DP; Stefansson K; van Duijri CM; Abecasis GR; Franke L; Frayling TM; McCarthy MI; Visscher PM; Scherag A; Willer CJ; Boehnke M; Mohlke KL; Lindgren CM; Beckmann JS; Barroso I; North KE; Ingelsson E; Hirschhorn JN; Loos RJF; Speliotes EK
Article: NATURE. 2015;518(7538):187-U378
New genetic loci link adipose and insulin biology to body fat distribution
Shungin D; Winkler TW; Croteau-Chonka DC; Ferreira T; Lockes AE; Maegi R; Strawbridge RJ; Pers TH; Fischer K; Justice AE; Workalemahu T; Wu JMW; Buchkovich ML; Heard-Costa NL; Roman TS; Drong AW; Song C; Gustafsson S; Day FR; Esko T; Fall T; Kutalik Z; Luan J; Randall JC; Scherag A; Vedantam S; Wood AR; Chen J; Fehrmann R; Karjalainen J; Kahali B; Liu C-T; Schmidt EM; Absher D; Amin N; Anderson D; Beekman M; Bragg-Gresham JL; Buyske S; Demirkan A; Ehret GB; Feitosa MF; Goel A; Jackson AU; Johnson T; Kleber ME; Kristiansson K; Mangino M; Leach IM; Medina-Gomez C; Palmer CD; Pasko D; Pechlivaniss S; Peters MJ; Prokopenko I; Stancakova A; Sung YJ; Tanakam T; Teumer A; Van Vliet-Ostaptchouk JV; Yengo L; Zhang W; Albrecht E; Arnlov J; Arscott GM; Bandinelli S; Barrett A; Bellis C; Bennett AJ; Berne C; Blueher M; Buhringer S; Bonnet F; Boettcher Y; Bruinenberg M; Carba DB; Caspersen IH; Clarke R; Daw EW; Deelen J; Deelman E; Delgado G; Doney ASF; Eklund N; Erdos MR; Estrada K; Eury E; Friedrichs N; Garcia ME; Giedraitis V; Gigante B; Go AS; Golay A; Grallert H; Grammer TB; Graessler J; Grewal J; Groves CJ; Haller T; Hallmans G; Hartman CA; Hassinen M; Hayward C; Heikkila K; Herzig K-H; Helmer Q; Hillege HL; Holmen O; Hunt SC; Isaacs A; Ittermann T; James AL; Johansson I; Juliusdottir T; Kalafati I-P; Kinnunen L; Koenig W; Kooner IK; Kratzer W; Lamina C; Leander K; Lee NR; Lichtner P; Lind L; Lindstrom J; Lobbens S; Lorentzon M; Mach F; Magnusson PKE; Mahajan A; McArdle WL; Menni C; Merger S; Mihailov E; Milani L; Mills R; Moayyeri A; Monda KL; Mooijaart SP; Muehleisen TW; Mulas A; Mueller G; Mueller-Nurasyid M; Nagaraja R; Nalls MA; Narisu N; Glorioso N; Nolte IM; Olden M; Rayner NW; Renstrom F; Ried JS; Robertson NR; Rose LM; Sanna S; Scharnagl H; Scholtens S; Sennblad B; Seufferlein T; Sitlani CM; Smith AV; Stirrups K; Stringham HM; Sundstrom J; Swertz MA; Swift AJ; Syvanen A-C; Tayo BO; Thorand B; Thorleifsson G; Tomaschitz A; Troffa C; van Oort FVA; Verweij N; Vonk JM; Waite LL; Wennauer R; Wilsgaard T; Wojczynski MK; Wong A; Zhang Q; Zhao JH; Brennan EP; Choi M; Eriksson P; Folkersen L; Franco-Cereceda A; Gharavi AG; Hedman AK; Hivert M-F; Huang J; Kanoni S; Karpe F; Keildson S; Kiryluk K; Liang L; Lifton RP; Ma B; McKnight AJ; McPherson R; Metspalu A; Min JL; Moffatt MF; Montgomery GW; Murabito JM; Nicholson G; Nyholt DR; Olsson C; Perry JRB; Reinmaa E; Salem RM; Sandholm N; Schadt EE; Scott RA; Stolk L; Vallejo EE; Westra H-J; Zondervan KT; Amouyel P; Arveiler D; Bakker SJL; Beilby J; Bergman RN; Blangero J; Brown MJ; Burnier M; Campbell H; Chakravarti A; Chiness PS; Claudi-Boehmi S; Collins FS; Crawford DC; Danesh J; de Faire U; de Geusl EJC; Doerr M; Erbel R; Eriksson JG; Farrall M; Ferrannini E; Ferrieres J; Forouhi NG; Forrester T; Franco OH; Gansevoort RT; Gieger C; Gudnason V; Haiman CA; Harris TB; Hattersley AT; Heliovaara M; Hicks AA; Hingorani AD; Hoffmann W; Hofman A; Homuth G; Humphries SE; Hyppoenen E; Illig T; Jarvelin M-R; Johansen B; Jousilahti P; Jula AM; Kaprio J; Kee F; Keinanen-Kiukaanniemi SM; Kooner JS; Kooperberg C; Kovacs P; Kraja AT; Kumari M; Kuulasmaa K; Kuusisto J; Lakka TA; Langenberg C; Le Marchand L; Lehtimaki T; Lyssenko V; Mannisto S; Marette A; Matise TC; McKenzie CA; McKnight B; Musk AW; Mohlenkamp S; Morris AD; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Palmer LJ; Penninx BW; Peters A; Pramstaller PP; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ridker PM; Ritchie MD; Rudan I; Salomaa V; Samani NJ; Saramies J; Sarzynski MA; Schwarz PEH; Shuldiner AR; Staessen JA; Steinthorsdottir V; Stolk RP; Strauch K; Toenjes A; Tremblay A; Tremoli E; Vohl M-C; Voelker U; Vollenweider P; Wilson JF; Witteman JC; Adair LS; Bochud M; Boehm BO; Bornstein SR; Bouchard C; Cauchi S; Caulfield MJ; Chambers JC; Chasman DI; Cooper RS; Dedoussis G; Ferrucci L; Froguel P; Grabe H-J; Hamsten A; Hui J; Hveem K; Joeckel K-H; Kivimaki M; Kuh D; Laakso M; Liu Y; Maerz W; Munroe PB; Njolstad I; Oostra BA; Palmer CNA; Pedersen NL; Perola M; Perusse L; Peters U; Power C; Quertermous T; Rauramaa R; Rivadeneira F; Saaristo TE; Saleheen D; Sinisalo J; Slagboom PE; Snieder H; Spector TD; Thorsteinsdottir UR; Stumvoll M; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Veronesi G; Walker M; Wareham NJ; Watkins H; Wichmann H-E; Abecasis GR; Assimes TL; Berndt SI; Boehnkes M; Borecki IB; Deloukas P; Franke L; Frayling TM; Groop LC; Hunter DJ; Kaplan RC; O'Connell JR; Qi L; Schlessinger D; Strachan DP; Stefansson K; van Dujin CM; Willer CJ; Visscher PM; Yang J; Hirschhorn JN; Zillikens MC; McCarthy MI; Speliotes EK; North KE; Fox CS; Barroso I; Franks PW; Ingelsson E; Heid IM; Loos RJF; Cupples LA; Morris AP; Lindgren CM; Mohlke KL
Article: NATURE. 2015;518(7537):102-106
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction
Do R; Stitziel NO; Won H-H; Jorgensen AB; Duga S; Merlini PA; Kiezun A; Farrall M; Goel A; Zuk O; Guella I; Asselta R; Lange LA; Peloso GM; Auer PL; Girelli D; Martinelli N; Farlow DN; DePristo MA; Roberts R; Stewart AFR; Saleheen D; Danesh J; Epstein SE; Sivapalaratnam S; Hovingh GK; Kastelein JJ; Samani NJ; Schunkert H; Erdmann J; Shah SH; Kraus WE; Davies R; Nikpay M; Johansen CT; Wang J; Hegele RA; Hechter E; Marz W; Kleber ME; Huang J; Johnson AD; Li M; Burke GL; Gross M; Liu Y; Assimes TL; Heiss G; Lange EM; Folsom AR; Taylor HA; Olivieri O; Hamsten A; Clarke R; Reilly DF; Yin W; Rivas MA; Donnelly P; Rossouw JE; Psaty BM; Herrington DM; Wilson JG; Rich SS; Bamshad MJ; Tracy RP; Cupples LA; Rader DJ; Reilly MP; Spertus JA; Cresci S; Hartiala J; Tang WHW; Hazen SL; Allayee H; Reiner AP; Carlson CS; Kooperberg C; Jackson RD; Boerwinkle E; Lander ES; Schwartz SM; Siscovick DS; McPherson R; Tybjaerg-Hansen A; Abecasis GR; Watkins H; Nickerson DA; Ardissino D; Sunyaev SR; O'Donnell CJ; Altshuler D; Gabriel S; Kathiresan S
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2015;13(2):219-227
Predicting venous thrombosis in women using a combination of genetic markers and clinical risk factors
Bruzelius M; Bottai M; Sabater-Lleal M; Strawbridge RJ; Bergendal A; Silveira A; Sundstrom A; Kieler H; Hamsten A; Odeberg J
Article: NATURE COMMUNICATIONS. 2015;6:5897
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility
Wessel J; Chu AY; Willems SM; Wang S; Yaghootkar H; Brody JA; Dauriz M; Hivert M-F; Raghavan S; Lipovich L; Hidalgo B; Fox K; Huffman JE; An P; Lu Y; Rasmussen-Torvik LJ; Grarup N; Ehm MG; Li L; Baldridge AS; Stancakova A; Abrol R; Besse C; Boland A; Bork-Jensen J; Fornage M; Freitag DF; Garcia ME; Guo X; Hara K; Isaacs A; Jakobsdottir J; Lange LA; Layton JC; Li M; Zhao JH; Meidtner K; Morrison AC; Nalls MA; Peters MJ; Sabater-Lleal M; Schurmann C; Silveira A; Smith AV; Southam L; Stoiber MH; Strawbridge RJ; Taylor KD; Varga TV; Allin KH; Amin N; Aponte JL; Aung T; Barbieri C; Bihlmeyer NA; Boehnke M; Bombieri C; Bowden DW; Burns SM; Chen Y; Chen Y-D; Cheng C-Y; Correa A; Czajkowski J; Dehghan A; Ehret GB; Eiriksdottir G; Escher SA; Farmaki A-E; Franberg M; Gambaro G; Giulianini F; Goddard WAIII; Goel A; Gottesman O; Grove ML; Gustafsson S; Hai Y; Hallmans G; Heo J; Hoffmann P; Ikram MK; Jensen RA; Jorgensen ME; Jorgensen T; Karaleftheri M; Khor CC; Kirkpatrick A; Kraja AT; Kuusisto J; Lange EM; Lee IT; Lee W-J; Leong A; Liao J; Liu C; Liu Y; Lindgren CM; Linneberg A; Malerba G; Mamakou V; Marouli E; Maruthur NM; Matchan A; McKean-Cowdin R; McLeod O; Metcalf GA; Mohlke KL; Muzny DM; Ntalla I; Palmer ND; Pasko D; Peter A; Rayner NW; Renstroem F; Rice K; Sala CF; Sennblad B; Serafetinidis I; Smith JA; Soranzo N; Speliotes EK; Stahl EA; Stirrups K; Tentolouris N; Thanopoulou A; Torres M; Traglia M; Tsafantakis E; Javad S; Yanek LR; Zengini E; Becker DM; Bis JC; Brown JB; Cupples LA; Hansen T; Ingelsson E; Karter AJ; Lorenzo C; Mathias RA; Norris JM; Peloso GM; Sheu WH-H; Toniolo D; Vaidya D; Varma R; Wagenknecht LE; Boeing H; Bottinger EP; Dedoussis G; Deloukas P; Ferrannini E; Franco OH; Franks PW; Gibbs RA; Gudnason V; Hamsten A; Harris TB; Hattersley AT; Hayward C; Hofman A; Jansson J-H; Langenberg C; Launer LJ; Levy D; Oostra BA; O'Donnell CJ; O'Rahilly S; Padmanabhan S; Pankow JS; Polasek O; Province MA; Rich SS; Ridker PM; Rudan I; Schulze MB; Smith BH; Uitterlinden AG; Walker M; Watkins H; Wong TY; Zeggini E; Laakso M; Borecki IB; Chasman DI; Pedersen O; Psaty BM; Tai ES; van Duijn CM; Wareham NJ; Waterworth DM; Boerwinkle E; Kao WHL; Florez JC; Loos RJF; Wilson JG; Frayling TM; Siscovick DS; Dupuis J; Rotter JI; Meigs JB; Scott RA; Goodarzi MO; Sharp SJ; Forouhi NG; Kerrison ND; Lucarelli DME; Sims M; Barroso I; McCarthy MI; Arriola L; Balkau B; Barricarte A; Gonzalez C; Grioni S; Kaaks R; Key TJ; Navarro C; Nilsson PM; Overvad K; Palli D; Panico S; Quiros JR; Rolandsson O; Sacerdote C; Sanchez M-J; Slimani N; Tjonneland A; Tumino R; van der A DL; van der Schouw YT; Riboli E
Article: THE LANCET. 2015;385(9965):351-361
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Swerdlow DI; Preiss D; Kuchenbaecker KB; Holmes MV; Engmann JEL; Shah T; Sofat R; Stender S; Johnson PCD; Scott RA; Leusink M; Verweij N; Sharp SJ; Guo Y; Giambartolomei C; Chung C; Peasey A; Amuzu A; Li K; Palmen J; Howard P; Cooper JA; Drenos F; Li YR; Lowe G; Gallacher J; Stewart MCW; Tzoulaki I; Buxbaum SG; Daphne LVDA; Forouhi NG; Onland-Moret NC; van der Schouw YT; Schnabel RB; Hubacek JA; Kubinova R; Baceviciene M; Tamosiunas A; Pajak A; Topor-Madry R; Stepaniak U; Malyutina SA; Baldassarre D; Sennblad B; Tremoli E; de Faire U; Veglia F; Ford I; Jukema JW; Westendorp RGJ; de Borst GJ; de Jong PA; Algra A; Spiering W; Maitland-van der Zee AH; Klungel OH; de Boer A; Doevendans PA; Eaton CB; Robinson JG; Duggan D; Kjekshus J; Downs JR; Gotto AM; Keech AC; Marchioli R; Tognoni G; Sever PS; Poulter NR; Waters DD; Pedersen TR; Amarenco P; Nakamura H; McMurray JJV; Lewsey JD; Chasman DI; Ridker PM; Maggioni AP; Tavazzi L; Ray KK; Seshasai SRK; Manson JE; Price JF; Whincup PH; Morris RW; Lawlor DA; Smith GD; Ben-Shlomo Y; Schreiner PJ; Fornage M; Siscovick DS; Cushman M; Kumari M; Wareham NJ; Verschuren WMM; Redline S; Patel SR; Whittaker JC; Hamsten A; Delaney JA; Dale C; Gaunt TR; Wong A; Kuh D; Hardy R; Kathiresan S; Castillo BA; van der Harst P; Brunner EJ; Tybjaerg-Hansen A; Marmot MG; Krauss RM; Tsai M; Coresh J; Hoogeveen RC; Psaty BM; Lange LA; Hakonarson H; Dudbridge F; Humphries SE; Talmud PJ; Kivimaeki M; Timpson NJ; Langenberg C; Asselbergs FW; Voevoda M; Bobak M; Pikhart H; Wilson JG; Reiner AP; Keating BJ; Hingorani AD; Sattar N
Article: PLOS ONE. 2015;10(3):e0119980
Analysis of the Role of Interleukin 6 Receptor Haplotypes in the Regulation of Circulating Levels of Inflammatory Biomarkers and Risk of Coronary Heart Disease
Gigante B; Strawbridge RJ; Velasquez IM; Golabkesh Z; Silveira A; Goel A; Baldassarre D; Veglia F; Tremoli E; Clarke R; Watkins H; Hamsten A; Humphries SE; de Faire U
Article: NATURE GENETICS. 2014;46(11):1173-1186
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood AR; Esko T; Yang J; Vedantam S; Pers TH; Gustafsson S; Chun AY; Estrada K; Luan J; Kutalik Z; Amin N; Buchkovich ML; Croteau-Chonka DC; Day FR; Duan Y; Fall T; Fehrmann R; Ferreira T; Jackson AU; Karjalainen J; Lo KS; Locke AE; Maegi R; Mihailov E; Porcu E; Randall JC; Scherag A; Vinkhuyzen AAE; Westra H-J; Winkler TW; Workalemahu T; Zhao JH; Absher D; Albrecht E; Anderson D; Baron J; Beekman M; Demirkan A; Ehret GB; Feenstra B; Feitosa MF; Fischer K; Fraser RM; Goel A; Gong J; Justice AE; Kanoni S; Kleber ME; Kristiansson K; Lim U; Lotay V; Lui JC; Mangino M; Leach IM; Medina-Gomez C; Nalls MA; Nyholt DR; Palmer CD; Pasko D; Pechlivanis S; Prokopenko I; Ried JS; Ripke S; Shungin D; Stancakova A; Strawbridge RJ; Sung YJ; Tanaka T; Teumer A; Trompet S; van der Laan SW; van Setten J; Van Vliet-Ostaptchouk JV; Wang Z; Yengo L; Zhang W; Afzal U; Arnloev J; Arscott GM; Bandinelli S; Barrett A; Bellis C; Bennett AJ; Berne C; Blueher M; Bolton JL; Boettcher Y; Boyd HA; Bruinenberg M; Buckley BM; Buyske S; Caspersen IH; Chines PS; Clarke R; Claudi-Boehm S; Cooper M; Daw EW; De Jong PA; Deelen J; Delgado G; Denny JC; Dhonukshe-Rutten R; Dimitriou M; Doney ASF; Doerr M; Eklund N; Eury E; Folkersen L; Garcia ME; Geller F; Giedraitis V; Go AS; Grallert H; Grammer TB; Graessler J; Groenberg H; de Groot LCPGM; Groves CJ; Haessler J; Hall P; Haller T; Hallmans G; Hannemann A; Hartman CA; Hassinen M; Hayward C; Heard-Costa NL; Helmer Q; Hemani G; Henders AK; Hillege HL; Hlatky MA; Hoffmann W; Hoffmann P; Holmen O; Houwing-Duistermaat JJ; Illig T; Isaacs A; James AL; Jeff J; Johansen B; Johansson A; Jolley J; Juliusdottir T; Junttila J; Kho AN; Kinnunen L; Klopp N; Kocher T; Kratzer W; Lichtner P; Lind L; Lindstroem J; Lobbens S; Lorentzon M; Lu Y; Lyssenko V; Magnusson PKE; Mahajan A; Maillard M; McArdle WL; McKenzie CA; McLachlan S; McLaren PJ; Menni C; Merger S; Milani L; Moayyeri A; Monda KL; Morken MA; Mueller G; Mueller-Nurasyid M; Musk AW; Narisu N; Nauck M; Nolte IM; Noethen MM; Oozageer L; Pilz S; Rayner NW; Renstrom F; Robertson NR; Rose LM; Roussel R; Sanna S; Scharnagl H; Scholtens S; Schumacher FR; Schunkert H; Scott RA; Sehmi J; Seufferlein T; Shin J; Silventoinen K; Smit JH; Smith AV; Smolonska J; Stanton AV; Stirrups K; Stott DJ; Stringham HM; Sundstrom J; Swertz MA; Syvanen A-C; Tayo BO; Thorleifsson G; Tyrer JP; van Dijk S; van Schoor NM; van der Velde N; van Heemst D; van Oort FVA; Vermeulen SH; Verweij N; Vonk JM; Waite LL; Waldenberger M; Wennauer R; Wilkens LR; Willenborg C; Wilsgaard T; Wojczynski MK; Wong A; Wright AF; Zhang Q; Arveiler D; Bakker SJL; Beilby J; Bergman RN; Bergmann S; Biffar R; Blangero J; Boomsma DI; Bornstein SR; Bovet P; Brambilla P; Brown MJ; Campbell H; Caulfield MJ; Chakravarti A; Collins R; Collins FS; Crawford DC; Cupples LA; Danesh J; de Faire U; den Ruijter HM; Erbel R; Erdmann J; Eriksson JG; Farrall M; Ferrannini E; Ferrieres J; Ford I; Forouhi NG; Forrester T; Gansevoort RT; Gejman PV; Gieger C; Golay A; Gottesman O; Gudnason V; Gyllensten U; Haas DW; Hall AS; Harris TB; Hattersley AT; Heath AC; Hengstenberg C; Hicks AA; Hindorff LA; Hingorani AD; Hofman A; Hovingh GK; Humphries SE; Hunt SC; Hypponen E; Jacobs KB; Jarvelin M-R; Jousilahti P; Jula AM; Kaprio J; Kastelein JJP; Kayser M; Kee F; Keinanen-Kiukaanniemi SM; Kiemeney LA; Kooner JS; Kooperberg C; Koskinen S; Kovacs P; Kraja AT; Kumari M; Kuusisto J; Lakka TA; Langenberg C; Le Marchand L; Lehtimaki T; Lupoli S; Madden PAF; Mannisto S; Manunta P; Marette A; Matise TC; McKnight B; Meitinger T; Moll FL; Montgomery GW; Morris AD; Morris AP; Murray JC; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Ouwehand WH; Pasterkamp G; Peters A; Pramstaller PP; Price JF; Qi L; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ritchie M; Rudan I; Salomaa V; Samani NJ; Saramies J; Sarzynski MA; Schwarz PEH; Sebert S; Sever P; Shuldiner AR; Sinisalo J; Steinthorsdottir V; Stolk RP; Tardif J-C; Toenjes A; Tremblay A; Tremoli E; Virtamo J; Vohl M-C; Amouyel P; Asselbergs FW; Assimes TL; Bochud M; Boehm BO; Boerwinkle E; Bottinger EP; Bouchard C; Cauchi S; Chambers JC; Chanock SJ; Cooper RS; de Bakker PIW; Dedoussis G; Ferrucci L; Franks PW; Froguel P; Groop LC; Haiman CA; Hamsten A; Hayes MG; Hui J; Hunter DJ; Hveem K; Jukema JW; Kaplan RC; Kivimaki M; Kuh D; Laakso M; Liu Y; Martin NG; Maerz W; Melbye M; Moebus S; Munroe PB; Njolstad I; Oostra BA; Palmer CNA; Pedersen NL; Perola M; Perusse L; Peters U; Powell JE; Power C; Quertermous T; Rauramaa R; Reinmaa E; Ridker PM; Rivadeneira F; Rotter JI; Saaristo TE; Saleheen D; Schlessinger D; Slagboom PE; Snieder H; Spector TD; Strauch K; Stumvoll M; Tuomilehto J; Uusitupa M; van der Harst P; Voelzke H; Walker M; Wareham NJ; Watkins H; Wichmann H-E; Wilson JF; Zanen P; Deloukas P; Heid IM; Lindgren CM; Mohlke KL; Speliotes EK; Thorsteinsdottir U; Barroso I; Fox CS; North KE; Strachan DP; Beckmann JS; Berndt SI; Boehnke M; Borecki IB; McCarthy MI; Metspalu A; Stefansson K; Uitterlinden AG; van Duijn CM; Franke L; Willer CJ; Price AL; Lettre G; Loos RJF; Weedon MN; Ingelsson E; O'Connell JR; Abecasis GR; Chasman DI; Goddard ME; Visscher PM; Hirschhorn JN; Frayling TM
Article: NATURE COMMUNICATIONS. 2014;5:5214
miR-24 limits aortic vascular inflammation and murine abdominal aneurysm development
Maegdefessel L; Spin JM; Raaz U; Eken SM; Toh R; Azuma J; Adam M; Nagakami F; Heymann HM; Chernugobova E; Jin H; Roy J; Hultgren R; Caidahl K; Schrepfer S; Hamsten A; Eriksson P; McConnell MV; Dalman RL; Tsao PS
Article: MOLECULAR MEDICINE. 2014;20(1):456-465
Human Genetic Evidence for Involvement of CD137 in Atherosclerosis
Soderstrom LA; Gertow K; Folkersen L; Sabater-Lleal M; Sundman E; Sheikine Y; Goel A; Baldassarre D; Humphries SE; de Faire U; Watkins H; Tremoli E; Veglia F; Hamsten A; Hansson GK; Olofsson PS
Article: ATHEROSCLEROSIS. 2014;236(2):394-399
Low levels of IgM antibodies against phosphorylcholine are associated with fast carotid intima media thickness progression and cardiovascular risk in men
Gigante B; Leander K; Vikstrom M; Baldassarre D; Veglia F; Strawbridge RJ; McLeod O; Gertow K; Sennblad B; Shah S; Zabaneh D; Humphries SE; Kauhanen JP; Rauramaa R; Smit AJ; Mannarino E; Giral P; Tremoli E; Hamsten A; Frostegard J; De Faire U
Article: JOURNAL OF INTERNAL MEDICINE. 2014;276(3):260-268
Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease
Hopewell JC; Seedorf U; Farrall M; Parish S; Kyriakou T; Goel A; Hamsten A; Collins R; Watkins H; Clarke R
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(9):2068-2077
Lim Domain Binding 2 A Key Driver of Transendothelial Migration of Leukocytes and Atherosclerosis
Shang M-M; Talukdar HA; Hofmann JJ; Niaudet C; Asl HF; Jain RK; Rossignoli A; Cedergren C; Silveira A; Gigante B; Leander K; de Faire U; Hamsten A; Ruusalepp A; Melander O; Ivert T; Michoel T; Schadt EE; Betsholtz C; Skogsberg J; Bjorkegren JLM
Article: THROMBOSIS RESEARCH. 2014;134(2):426-432
Influence of coronary artery disease-associated genetic variants on risk of venous thromboembolism
Bruzelius M; Strawbridge RJ; Tregouet D-A; Wiggins KL; Gertow K; Sabater-Lleal M; Ohrvik J; Bergendal A; Silveira A; Sundstrom A; Kieler H; Syvanen A-C; Smith NL; Morange P-E; Odeberg J; Hamsten A
Article: THE BMJ. 2014;349:g4164
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
Holmes MV; Dale CE; Zuccolo L; Silverwood RJ; Guo Y; Ye Z; Prieto-Merino D; Dehghan A; Trompet S; Wong A; Cavadino A; Drogan D; Padmanabhan S; Li S; Yesupriya A; Leusink M; Sundstrom J; Hubacek JA; Pikhart H; Swerdlow DI; Panayiotou AG; Borinskaya SA; Finan C; Shah S; Kuchenbaecker KB; Shah T; Engmann J; Folkersen L; Eriksson P; Ricceri F; Melander O; Sacerdote C; Gamble DM; Rayaprolu S; Ross OA; McLachlan S; Vikhireva O; Sluijs I; Scott RA; Adamkova V; Flicker L; Van Bockxmeer FM; Power C; Marques-Vidal P; Meade T; Marmot MG; Ferro JM; Paulos-Pinheiro S; Humphries SE; Talmud PJ; Leach IM; Verweij N; Linneberg A; Skaaby T; Doevendans PA; Cramer MJ; Van der Harst P; Klungel OH; Dowling NF; Dominiczak AF; Kumari M; Nicolaides AN; Weikert C; Boeing H; Ebrahim S; Gaunt TR; Price JF; Lannfelt L; Peasey A; Kubinova R; Pajak A; Malyutina S; Voevoda MI; Tamosiunas A; Maitland-van der Zee AH; Norman PE; Hankey GJ; Bergmann MM; Hofman A; Franco OH; Cooper J; Palmen J; Spiering W; de Jong PA; Kuh D; Hardy R; Uitterlinden AG; Ikram MA; Ford I; Hyppoenen E; Almeida OP; Wareham NJ; Khaw K-T; Hamsten A; Husemoen LLN; Tjonneland A; Tolstrup JS; Rimm E; Beulens JWJ; Verschuren WMM; Onland-Moret NC; Hofker MH; Wannamethee SG; Whincup PH; Morris R; Vicente AM; Watkins H; Farrall M; Jukema JW; Meschia J; Cupples LA; Sharp SJ; Fornage M; Kooperberg C; LaCroix AZ; Dai JY; Lanktree MB; Siscovick DS; Jorgenson E; Spring B; Coresh J; Li YR; Buxbaum SG; Schreiner PJ; Ellison RC; Tsai MY; Patel SR; Redline S; Johnson AD; Hoogeveen RC; Rotter JI; Boerwinkle E; de Bakker PIW; Kivimaki M; Asselbergs FW; Sattar N; Lawlor DA; Whittaker J; Smith GD; Mukamal K; Psaty BM; Wilson JG; Lange LA; Hamidovic A; Hingorani AD; Nordestgaard BG; Bobak M; Leon DA; Langenberg C; Palmer TM; Reiner AP; Keating BJ; Dudbridge F; Casas JP
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2014;111(24):8913-8918
TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content
Mahdessian H; Taxiarchis A; Popov S; Silveira A; Franco-Cereceda A; Hamsten A; Eriksson P; van't Hooft F
Article: DIABETOLOGIA. 2014;57(6):1159-1172
A serum 25-hydroxyvitamin D concentration-associated genetic variant in DHCR7 interacts with type 2 diabetes status to influence subclinical atherosclerosis (measured by carotid intima-media thickness)
Strawbridge RJ; Deleskog A; McLeod O; Folkersen L; Kavousi M; Gertow K; Baldassarre D; Veglia F; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Dehghan A; Hofman A; Franco OH; Humphries SE; Tremoli E; de Faire U; Gustafsson S; Ostensson C-G; Eriksson P; Ohrvik J; Hamsten A
Article: JOURNAL OF INTERNAL MEDICINE. 2014;275(6):640-651
The HLA locus contains novel foetal susceptibility alleles for congenital heart block with significant paternal influence
Meisgen S; Ostberg T; Salomonsson S; Ding B; Eliasson H; Malarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Axelsson T; Gadler F; Jonzon A; Sonesson S-E; Kockum I; Wahren-Herlenius M
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2014;34(5):1093-1101
Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2
Huang J; Huffman JE; Yamkauchi M; Trompet S; Asselbergs FW; Sabater-Lleal M; Tregouet D-A; Chen W-M; Smith NL; Kleber ME; Shin S-Y; Becker DM; Tang W; Dehghan A; Johnson AD; Vinh T; Folkersen L; Yang Q; Oudot-Mellkah T; Buckley BM; Moore JH; Williams FMK; Campbell H; Silbernagel G; Vitart V; Rudan I; Tofler GH; Navis GJ; DeStefano A; Wright AF; Chen M-H; de Craen AJM; Worrall BB; Rudnicka AR; Rumley A; Bookman EB; Psaty BM; Chen F; Keene KL; Franco OH; Boehm BO; Uitterlinden AG; Carter AM; Jukema JW; Sattar N; Bis JC; Ikram MA; Sale MM; McKnight B; Fornage M; Ford I; Taylor K; Slagboom PE; McArdle WL; Hsu F-C; Franco-Cereceda A; Goodall AH; Yanek LR; Furie KL; Cushman M; Hofman A; Witteman JCM; Folsom AR; Basu S; Matijevic N; van Gilst WH; Wilson JF; Westendorp RGJ; Kathiresan S; Reilly MP; Tracy RP; Polasek O; Winkelmann BR; Grant PJ; Hillege HL; Cambien F; Stott DJ; Lowe GD; Spector TD; Meigs JB; Marz W; Eriksson P; Becker LC; Morange P-E; Soranzo N; Williams SM; Hayward C; van der Harst P; Hamsten A; Lowenstein CJ; Strachan DP; O'Donnell CJ
Article: NATURE GENETICS. 2014;46(3):234-244
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
Mahajan A; Go MJ; Zhang W; Below JE; Gaulton KJ; Ferreira T; Horikoshi M; Johnson AD; Ng MCY; Prokopenko I; Saleheen D; Wang X; Zeggini E; Abecasis GR; Adair LS; Almgren P; Atalay M; Aung T; Baldassarre D; Balkau B; Bao Y; Barnett AH; Barroso I; Basit A; Been LF; Beilby J; Bell GI; Benediktsson R; Bergman RN; Boehm BO; Boerwinkle E; Bonnycastle LL; Burtt N; Cai Q; Campbell H; Carey J; Cauchi S; Caulfield M; Chan JCN; Chang L-C; Chang T-J; Chang Y-C; Charpentier G; Chen C-H; Chen H; Chen Y-T; Chia K-S; Chidambaram M; Chines PS; Cho NH; Cho YM; Chuang L-M; Collins FS; Cornelis MC; Couper DJ; Crenshaw AT; van Dam RM; Danesh J; Das D; de Faire U; Dedoussis G; Deloukas P; Dimas AS; Dina C; Doney ASF; Donnelly PJ; Dorkhan M; van Duijn C; Dupuis J; Edkins S; Elliott P; Emilsson V; Erbel R; Eriksson JG; Escobedo J; Esko T; Eury E; Florez JC; Fontanillas P; Forouhi NG; Forsen T; Fox C; Fraser RM; Frayling TM; Froguel P; Frossard P; Gao Y; Gertow K; Gieger C; Gigante B; Grallert H; Grant GB; Groop LC; Groves CJ; Grundberg E; Guiducci C; Hamsten A; Han B-G; Hara K; Hassanali N; Hattersley AT; Hayward C; Hedman AK; Herder C; Hofman A; Holmen OL; Hovingh K; Hreidarsson AB; Hu C; Hu FB; Hui J; Humphries SE; Hunt SE; Hunter DJ; Hveem K; Hydrie ZI; Ikegami H; Illig T; Ingelsson E; Islam M; Isomaa B; Jackson AU; Jafar T; James A; Jia W; Joeckel K-H; Jonsson A; Jowett JBM; Kadowaki T; Kang HM; Kanoni S; Kao WHL; Kathiresan S; Kato N; Katulanda P; Keinanen-Kiukaanniemi SM; Kelly AM; Khan H; Khaw K-T; Khor C-C; Kim H-L; Kim S; Kim YJ; Kinnunen L; Klopp N; Kong A; Korpi-Hyovalti E; Kowlessur S; Kraft P; Kravic J; Kristensen MM; Krithika S; Kumar A; Kumate J; Kuusisto J; Kwak SH; Laakso M; Lagou V; Lakka TA; Langenberg C; Langford C; Lawrence R; Leander K; Lee J-M; Lee NR; Li M; Li X; Li Y; Liang J; Liju S; Lim W-Y; Lind L; Lindgren CM; Lindholm E; Liu C-T; Liu JJ; Lobbens S; Long J; Loos RJF; Lu W; Luan J; Lyssenko V; Ma RCW; Maeda S; Maegi R; Mannisto S; Matthews DR; Meigs JB; Melander O; Metspalu A; Meyer J; Mirza G; Mihailov E; Moebus S; Mohan V; Mohlke KL; Morris AD; Muehleisen TW; Mueller-Nurasyid M; Musk B; Nakamura J; Nakashima E; Navarro P; Peng-Keat N; Nica AC; Nilsson PM; Njolstad I; Noethen MM; Ohnaka K; Ong TH; Owen KR; Palmer CNA; Pankow JS; Park KS; Parkin M; Pechlivanis S; Pedersen NL; Peltonen L; Perry JRB; Peters A; Pinidiyapathirage JM; Platou CGP; Potter S; Price JF; Qi L; Radha V; Rallidis L; Rasheed A; Rathmann W; Rauramaa R; Raychaudhuri S; Rayner NW; Rees SD; Rehnberg E; Ripatti S; Robertson N; Roden M; Rossin EJ; Rudan I; Rybin D; Saaristo TE; Salomaa V; Saltevo J; Samuel M; Sanghera DK; Saramies J; Scott J; Scott LJ; Scott RA; Segre AV; Sehmi J; Sennblad B; Shah N; Shah S; Shera AS; Shu XO; Shuldiner AR; Sigurdsson G; Sijbrands E; Silveira A; Sim X; Sivapalaratnam S; Small KS; So WY; Stancakova A; Stefansson K; Steinbach G; Steinthorsdottir V; Stirrups K; Strawbridge RJ; Stringham HM; Sun Q; Suo C; Syvanen A-C; Takayanagi R; Takeuchi F; Tay WT; Teslovich TM; Thorand B; Thorleifsson G; Thorsteinsdottir U; Tikkanen E; Trakalo J; Tremoli E; Trip MD; Tsai FJ; Tuomi T; Tuomilehto J; Uitterlinden AG; Valladares-Salgado A; Vedantam S; Veglia F; Voight BF; Wang C; Wareham NJ; Wennauer R; Wickremasinghe AR; Wilsgaard T; Wilson JF; Wiltshire S; Winckler W; Wong TY; Wood AR; Wu J-Y; Wu Y; Yamamoto K; Yamauchi T; Yang M; Yengo L; Yokota M; Young R; Zabaneh D; Zhang F; Zhang R; Zheng W; Zimmet PZ; Altshuler D; Bowden DW; Cho YS; Cox NJ; Cruz M; Hanis CL; Kooner J; Lee J-Y; Seielstad M; Teo YY; Boehnke M; Parra EJ; Chambers JC; Tai ES; McCarthy MI; Morris AP
Article: PLOS GENETICS. 2014;10(2):e1004201
Plasma Cholesterol-Induced Lesion Networks Activated before Regression of Early, Mature, and Advanced Atherosclerosis
Bjorkegren JLM; Hagg S; Talukdar HA; Asl HF; Jain RK; Cedergren C; Shang M-M; Rossignoli A; Takolander R; Melander O; Hamsten A; Michoel T; Skogsberg J
Article: PLOS ONE. 2014;9(4):e95771
Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake
Popov S; Takemori H; Tokudome T; Mao Y; Otani K; Mochizuki N; Pires N; Pinho MJ; Franco-Cereceda A; Torielli L; Ferrandi M; Hamsten A; Soares-da-Silva P; Eriksson P; Bertorello AM; Brion L
Article: PLOS ONE. 2014;9(12):e111156
No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects
Baumert J; Huang J; McKnight B; Sabater-Lleal M; Steri M; Chu AY; Trompet S; Lopez LM; Fornage M; Teumer A; Tang W; Rudnicka AR; Maelarstig A; Hottenga J-J; Kavousi M; Lahti J; Tanaka T; Hayward C; Huffman JE; Morange P-E; Rose LM; Basu S; Rumley A; Stott DJ; Buckley BM; de Craen AJM; Sanna S; Masala M; Biffar R; Homuth G; Silveira A; Sennblad B; Goel A; Watkins H; Mueller-Nurasyid M; Rueckerl R; Taylor K; Chen M-H; de Geus EJC; Hofman A; Witteman JCM; de Maat MPM; Palotie A; Davies G; Siscovick DS; Kolcic I; Wild SH; Song J; McArdle WL; Ford I; Sattar N; Schlessinger D; Grotevendt A; Franzosi MG; Illig T; Waldenberger M; Lumley T; Tofler GH; Willemsen G; Uitterlinden AG; Rivadeneira F; Raeikkonen K; Chasman DI; Folsom AR; Lowe GD; Westendorp RGJ; Slagboom PE; Cucca F; Wallaschofski H; Strawbridge RJ; Seedorf U; Koenig W; Bis JC; Mukamal KJ; van Dongen J; Widen E; Franco OH; Starr JM; Liu K; Ferrucci L; Polasek O; Wilson JF; Oudot-Mellakh T; Campbell H; Navarro P; Bandinelli S; Eriksson J; Boomsma DI; Dehghan A; Clarke R; Hamsten A; Boerwinkle E; Jukema JW; Naitza S; Ridker PM; Voezke H; Deary IJ; Reiner AP; Tregoueet D-A; O'Donnell CJ; Strachan DP; Peters A; Smith NL
Article: PLOS ONE. 2014;9(12):e113740
Detection of Circulating hcmv-miR-UL112-3p in Patients with Glioblastoma, Rheumatoid Arthritis, Diabetes Mellitus and Healthy Controls
Mohammad A-A; Rahbar A; Lui W-O; Davoudi B; Catrina A; Stragliotto G; Mellbin L; Hamsten A; Ryden L; Yaiw K-C; Soderberg-Naucler C
Article: PLOS ONE. 2014;9(8):e104082
Common Genetic Determinants of Lung Function, Subclinical Atherosclerosis and Risk of Coronary Artery Disease
Sabater-Lleal M; Maelarstig A; Folkersen L; Artigas MS; Baldassarre D; Kavousi M; Almgren P; Veglia F; Brusselle G; Hofman A; Engstrom G; Franco OH; Melander O; Paulsson-Berne G; Watkins H; Eriksson P; Humphries SE; Tremoli E; de Faire U; Tobin MD; Hamsten A
Article: ATHEROSCLEROSIS. 2014;232(1):242-248
Plasma autoantibodies against apolipoprotein B-100 peptide 210 in subclinical atherosclerosis
McLeod O; Silveira A; Fredrikson GN; Gertow K; Baldassarre D; Veglia F; Sennblad B; Strawbridge RJ; Larsson M; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Humphries SE; Tremoli E; de Faire U; Ohrvik J; Nilsson J; Hamsten A
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2013;62(21):1966-1976
Secretory Phospholipase A₂-IIA and Cardiovascular Disease
Holmes MV; Simon T; Exeter HJ; Folkersen L; Asselbergs FW; Guardiola M; Cooper JA; Palmen J; Hubacek JA; Carruthers KF; Horne BD; Brunisholz KD; Mega JL; Van Iperen EPA; Li M; Leusink M; Trompet S; Verschuren JJW; Hovingh GK; Dehghan A; Nelson CP; Kotti S; Danchin N; Scholz M; Haase CL; Rothenbacher D; Swerdlow DI; Kuchenbaecker KB; Staines-Urias E; Goel A; van 't Hooft F; Gertow K; de Faire U; Panayiotou AG; Tremoli E; Baldassarre D; Veglia F; Holdt LM; Beutner F; Gansevoort RT; Navis GJ; Leach IM; Breitling LP; Brenner H; Thiery J; Dallmeier D; Franco-Cereceda A; Boer JMA; Stephens JW; Hofker MH; Tedgui A; Hofman A; Uitterlinden AG; Adamkova V; Pitha J; Onland-Moret NC; Cramer MJ; Nathoe HM; Spiering W; Klungel OH; Kumari M; Whincup PH; Morrow DA; Braund PS; Hall AS; Olsson AG; Doevendans PA; Trip MD; Tobin MD; Hamsten A; Watkins H; Koenig W; Nicolaides AN; Teupser D; Day INM; Carlquist JF; Gaunt TR; Ford I; Sattar N; Tsimikas S; Schwartz GG; Lawlor DA; Morris RW; Sandhu MS; Poledne R; Maitland-van der Zee AH; Khaw K-T; Keating BJ; van der Harst P; Price JF; Mehta SR; Yusuf S; Witteman JCM; Franco OH; Jukema JW; de Knijff P; Tybjaerg-Hansen A; Rader DJ; Farrall M; Samani NJ; Kivimaki M; Fox KAA; Humphries SE; Anderson JL; Boekholdt SM; Palmer TM; Eriksson P; Pare G; Hingorani AD; Sabatine MS; Mallat Z; Casas JP; Talmud PJ
Article: NATURE GENETICS. 2013;45(11):1274-1283
Discovery and refinement of loci associated with lipid levels
Willer CJ; Schmidt EM; Sengupta S; Peloso GM; Gustafsson S; Kanoni S; Ganna A; Chen J; Buchkovich ML; Mora S; Beckmann JS; Bragg-Gresham JL; Chang H-Y; Demirkan A; Den Hertog HM; Do R; Donnelly LA; Ehret GB; Esko T; Feitosa MF; Ferreira T; Fischer K; Fontanillas P; Fraser RM; Freitag DF; Gurdasani D; Heikkila K; Hyppoenen E; Isaacs A; Jackson AU; Johansson A; Johnson T; Kaakinen M; Kettunen J; Kleber ME; Li X; Luan J; Lyytikainen L-P; Magnusson PKE; Mangino M; Mihailov E; Montasser ME; Mueller-Nurasyid M; Nolte IM; O'Connell JR; Palmer CD; Perola M; Petersen A-K; Sanna S; Saxena R; Service SK; Shah S; Shungin D; Sidore C; Song C; Strawbridge RJ; Surakka I; Tanaka T; Teslovich TM; Thorleifsson G; Van den Herik EG; Voight BF; Volcik KA; Waite LL; Wong A; Wu Y; Zhang W; Absher D; Asiki G; Barroso I; Been LF; Bolton JL; Bonnycastle LL; Brambilla P; Burnett MS; Cesana G; Dimitriou M; Doney ASF; Doering A; Elliott P; Epstein SE; Eyjolfsson GI; Gigante B; Goodarzi MO; Grallert H; Gravito ML; Groves CJ; Hallmans G; Hartikainen A-L; Hayward C; Hernandez D; Hicks AA; Holm H; Hung Y-J; Illig T; Jones MR; Kaleebu P; Kastelein JJP; Khaw K-T; Kim E; Klopp N; Komulainen P; Kumari M; Langenberg C; Lehtimaki T; Lin S-Y; Lindstrom J; Loos RJF; Mach F; McArdle WL; Meisinger C; Mitchell BD; Mueller G; Nagaraja R; Narisu N; Nieminen TVM; Nsubuga RN; Olafsson I; Ong KK; Palotie A; Papamarkou T; Pomilla C; Pouta A; Rader DJ; Reilly MP; Ridker PM; Rivadeneira F; Rudan I; Ruokonen A; Samani N; Scharnagl H; Seeley J; Silander K; Stancakova A; Stirrups K; Swift AJ; Tiret L; Uitterlinden AG; van Pelt LJ; Vedantam S; Wainwright N; Wijmenga C; Wild SH; Willemsen G; Wilsgaard T; Wilson JF; Young EH; Zhao JH; Adair LS; Arveiler D; Assimes TL; Bandinelli S; Bennett F; Bochud M; Boehm BO; Boomsma DI; Borecki IB; Bornstein SR; Bovet P; Burnier M; Campbell H; Chakravarti A; Chambers JC; Chen Y-DI; Collins FS; Cooper RS; Danesh J; Dedoussis G; de Faire U; Feranil AB; Ferrieres J; Ferrucci L; Freimer NB; Gieger C; Groop LC; Gudnason V; Gyllensten U; Hamsten A; Harris TB; Hingorani A; Hirschhorn JN; Hofman A; Hovingh GK; Hsiung CA; Humphries SE; Hunt SC; Hveem K; Iribarren C; Jarvelin M-R; Jula A; Kahonen M; Kaprio J; Kesaniemi A; Kivimaki M; Kooner JS; Koudstaal PJ; Krauss RM; Kuh D; Kuusisto J; Kyvik KO; Laakso M; Lakka TA; Lind L; Lindgren CM; Martin NG; Maerz W; McCarthy MI; McKenzie CA; Meneton P; Metspalu A; Moilanen L; Morris AD; Munroe PB; Njolstad I; Pedersen NL; Power C; Pramstaller PP; Price JF; Psaty BM; Quertermous T; Rauramaa R; Saleheen D; Salomaa V; Sanghera DK; Saramies J; Schwarz PEH; Sheu WH-H; Shuldiner AR; Siegbahn A; Spector TD; Stefansson K; Strachan DP; Tayo BO; Tremoli E; Tuomilehto J; Uusitupa M; van Duijn CM; Vollenweider P; Wallentin L; Wareham NJ; Whitfield JB; Wolffenbuttel BHR; Ordovas JM; Boerwinkle E; Palmer CNA; Thorsteinsdottir U; Chasman DI; Rotter JI; Franks PW; Ripatti S; Cupples LA; Sandhu MS; Rich SS; Boehnke M; Deloukas P; Kathiresan S; Mohlke KL; Ingelsson E; Abecasis GR
Article: NATURE GENETICS. 2013;45(11):1345-1352
Common variants associated with plasma triglycerides and risk for coronary artery disease
Do R; Willer CJ; Schmidt EM; Sengupta S; Gao C; Peloso GM; Gustafsson S; Kanoni S; Ganna A; Chen J; Buchkovich ML; Mora S; Beckmann JS; Bragg-Gresham JL; Chang H-Y; Demirkan A; Den Hertog HM; Donnelly LA; Ehret GB; Esko T; Feitosa MF; Ferreira T; Fischer K; Fontanillas P; Fraser RM; Freitag DF; Gurdasani D; Heikkila K; Hyppoenen E; Isaacs A; Jackson AU; Johansson A; Johnson T; Kaakinen M; Kettunen J; Kleber ME; Li X; Luan J; Lyytikainen L-P; Magnusson PKE; Mangino M; Mihailov E; Montasser ME; Mueller-Nurasyid M; Nolte IM; O'Connell JR; Palmer CD; Perola M; Petersen A-K; Sanna S; Saxena R; Service SK; Shah S; Shungin D; Sidore C; Song C; Strawbridge RJ; Surakka I; Tanaka T; Teslovich TM; Thorleifsson G; Van den Herik EG; Voight BF; Volcik KA; Waite LL; Wong A; Wu Y; Zhang W; Absher D; Asiki G; Barroso I; Been LF; Bolton JL; Bonnycastle LL; Brambilla P; Burnett MS; Cesana G; Dimitriou M; Doney ASF; Doering A; Elliott P; Epstein SE; Eyjolfsson GI; Gigante B; Goodarzi MO; Grallert H; Gravito ML; Groves CJ; Hallmans G; Hartikainen A-L; Hayward C; Hernandez D; Hicks AA; Holm H; Hung Y-J; Illig T; Jones MR; Kaleebu P; Kastelein JJP; Khaw K-T; Kim E; Klopp N; Komulainen P; Kumari M; Langenberg C; Lehtimaki T; Lin S-Y; Lindstrom J; Loos RJF; Mach F; McArdle WL; Meisinger C; Mitchell BD; Mueller G; Nagaraja R; Narisu N; Nieminen TVM; Nsubuga RN; Olafsson I; Ong KK; Palotie A; Papamarkou T; Pomilla C; Pouta A; Rader DJ; Reilly MP; Ridker PM; Rivadeneira F; Rudan I; Ruokonen A; Samani N; Scharnagl H; Seeley J; Silander K; Stancakova A; Stirrups K; Swift AJ; Tiret L; Uitterlinden AG; van Pelt LJ; Vedantam S; Wainwright N; Wijmenga C; Wild SH; Willemsen G; Wilsgaard T; Wilson JF; Young EH; Zhao JH; Adair LS; Arveiler D; Assimes TL; Bandinelli S; Bennett F; Bochud M; Boehm BO; Boomsma DI; Borecki IB; Bornstein SR; Bovet P; Burnier M; Campbell H; Chakravarti A; Chambers JC; Chen Y-DI; Collins FS; Cooper RS; Danesh J; Dedoussis G; de Faire U; Feranil AB; Ferrieres J; Ferrucci L; Freimer NB; Gieger C; Groop LC; Gudnason V; Gyllensten U; Hamsten A; Harris TB; Hingorani A; Hirschhorn JN; Hofman A; Hovingh GK; Hsiung CA; Humphries SE; Hunt SC; Hveem K; Iribarren C; Jarvelin M-R; Jula A; Kahonen M; Kaprio J; Kesaniemi A; Kivimaki M; Kooner JS; Koudstaal PJ; Krauss RM; Kuh D; Kuusisto J; Kyvik KO; Laakso M; Lakka TA; Lind L; Lindgren CM; Martin NG; Maerz W; McCarthy MI; McKenzie CA; Meneton P; Metspalu A; Moilanen L; Morris AD; Munroe PB; Njolstad I; Pedersen NL; Power C; Pramstaller PP; Price JF; Psaty BM; Quertermous T; Rauramaa R; Saleheen D; Salomaa V; Sanghera DK; Saramies J; Schwarz PEH; Sheu WH-H; Shuldiner AR; Siegbahn A; Spector TD; Stefansson K; Strachan DP; Tayo BO; Tremoli E; Tuomilehto J; Uusitupa M; van Duijn CM; Vollenweider P; Wallentin L; Wareham NJ; Whitfield JB; Wolffenbuttel BHR; Altshuler D; Ordovas JM; Boerwinkle E; Palmer CNA; Thorsteinsdottir U; Chasman DI; Rotter JI; Franks PW; Ripatti S; Cupples LA; Sandhu MS; Rich SS; Boehnke M; Deloukas P; Mohlke KL; Ingelsson E; Abecasis GR; Daly MJ; Neale BM; Kathiresan S
Article: NATURE GENETICS. 2013;45(11):1353-1360
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
Beecham AH; Patsopoulos NA; Xifara DK; Davis MF; Kemppinen A; Cotsapas C; Shah TS; Spencer C; Booth D; Goris A; Oturai A; Saarela J; Fontaine B; Hemmer B; Martin C; Zipp F; D'Alfonso S; Martinelli-Boneschi F; Taylor B; Harbo HF; Kockum I; Hillert J; Olsson T; Ban M; Oksenberg JR; Hintzen R; Barcellos LF; Agliardi C; Alfredsson L; Alizadeh M; Anderson C; Andrews R; Sondergaard HB; Baker A; Band G; Baranzini SE; Barizzone N; Barrett J; Bellenguez C; Bergamaschi L; Bernardinelli L; Berthele A; Biberacher V; Binder TMC; Blackburn H; Bomfim IL; Brambilla P; Broadley S; Brochet B; Brundin L; Buck D; Butzkueven H; Caillier SJ; Camu W; Carpentier W; Cavalla P; Celius EG; Coman I; Comi G; Corrado L; Cosemans L; Cournu-Rebeix I; Cree BAC; Cusi D; Damotte V; Defer G; Delgado SR; Deloukas P; di Sapio A; Dilthey AT; Donnelly P; Dubois B; Duddy M; Edkins S; Elovaara I; Esposito F; Evangelou N; Fiddes B; Field J; Franke A; Freeman C; Frohlich IY; Galimberti D; Gieger C; Gourraud P-A; Graetz C; Graham A; Grummel V; Guaschino C; Hadjixenofontos A; Hakonarson H; Halfpenny C; Hall G; Hall P; Hamsten A; Harley J; Harrower T; Hawkins C; Hellenthal G; Hillier C; Hobart J; Hoshi M; Hunt SE; Jagodic M; Jelcic I; Jochim A; Kendall B; Kermode A; Kilpatrick T; Koivisto K; Konidari I; Korn T; Kronsbein H; Langford C; Larsson M; Lathrop M; Lebrun-Frenay C; Lechner-Scott J; Lee MH; Leone MA; Leppa V; Liberatore G; Lie BA; Lill CM; Linden M; Link J; Luessi F; Lycke J; Macciardi F; Mannisto S; Manrique CP; Martin R; Martinelli V; Mason D; Mazibrada G; McCabe C; Mero I-L; Mescheriakova J; Moutsianas L; Myhr K-M; Nagels G; Nicholas R; Nilsson P; Piehl F; Pirinen M; Price SE; Quach H; Reunanen M; Robberecht W; Robertson NP; Rodegher M; Rog D; Salvetti M; Schnetz-Boutaud NC; Sellebjerg F; Selter RC; Schaefer C; Shaunak S; Shen L; Shields S; Siffrin V; Slee M; Sorensen PS; Sorosina M; Sospedra M; Spurkland A; Strange A; Sundqvist E; Thijs V; Thorpe J; Ticca A; Tienari P; van Duijn C; Visser EM; Vucic S; Westerlind H; Wiley JS; Wilkins A; Wilson JF; Winkelmann J; Zajicek J; Zindler E; Haines JL; Pericak-Vance MA; Ivinson AJ; Stewart G; Hafler D; Hauser SL; Compston A; McVean G; De Jager P; Sawcer SJ; McCauley JL
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(11):2633-2638
Serum 25-Hydroxyvitamin D Concentration in Subclinical Carotid Atherosclerosis
Deleskog A; Piksasova O; Silveira A; Gertow K; Baldassarre D; Veglia F; Sennblad B; Strawbridge RJ; Larsson M; Leander K; Gigante B; Kauhanen J; Rauramaa R; Smit AJ; Mannarino E; Giral P; Gustafsson S; Ostenson C-G; Humphries SE; Tremoli E; de Faire U; Ohrvik J; Hamsten A
Article: CIRCULATION. 2013;128(12):1310-1324
Multiethnic Meta-Analysis of Genome-Wide Association Studies in > 100 000 Subjects Identifies 23 FibrinogenAssociated Loci but No Strong Evidence of a Causal Association Between Circulating Fibrinogen and Cardiovascular Disease
Sabater-Lleal M; Huang J; Chasman D; Naitza S; Dehghan A; Johnson AD; Teumer A; Reiner AP; Folkersen L; Basu S; Rudnicka AR; Trompet S; Malarstig A; Baumert J; Bis JC; Guo X; Hottenga JJ; Shin S-Y; Lopez LM; Lahti J; Tanaka T; Yanek LR; Oudot-Mellakh T; Wilson JF; Navarro P; Huffman JE; Zemunik T; Redline S; Mehra R; Pulanic D; Rudan I; Wright AF; Kolcic I; Polasek O; Wild SH; Campbell H; Curb JD; Wallace R; Liu S; Eaton CB; Becker DM; Becker LC; Bandinelli S; Raikkonen K; Widen E; Palotie A; Fornage M; Green D; Gross M; Davies G; Harris SE; Liewald DC; Starr JM; Williams FMK; Grant PJ; Spector TD; Strawbridge RJ; Silveira A; Sennblad B; Rivadeneira F; Uitterlinden AG; Franco OH; Hofman A; van Dongen J; Willemsen G; Boomsma DI; Yao J; Jenny NS; Haritunians T; McKnight B; Lumley T; Taylor KD; Rotter JI; Psaty BM; Peters A; Gieger C; Illig T; Grotevendt A; Homuth G; Voelzke H; Kocher T; Goel A; Franzosi MG; Seedorf U; Clarke R; Steri M; Tarasov KV; Sanna S; Schlessinger D; Stott DJ; Sattar N; Buckley BM; Rumley A; Lowe GD; McArdle WL; Chen M-H; Tofler GH; Song J; Boerwinkle E; Folsom AR; Rose LM; Franco-Cereceda A; Teichert M; Ikram MA; Mosley TH; Bevan S; Dichgans M; Rothwell PM; Sudlow CLM; Hopewell JC; Chambers JC; Saleheen D; Kooner JS; Danesh J; Nelson CP; Erdmann J; Reilly MP; Kathiresan S; Schunkert H; Morange P-E; Ferrucci L; Eriksson JG; Jacobs D; Deary IJ; Soranzo N; Witteman JCM; de Geus EJC; Tracy RP; Hayward C; Koenig W; Cucca F; Jukema JW; Eriksson P; Seshadri S; Markus HS; Watkins H; Samani NJ; Wallaschofski H; Smith NL; Tregouet D; Ridker PM; Tang W; Strachan DP; Hamsten A; O'Donnell CJ
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2013;98(3):668-676
Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease
van Meurs JBJ; Pare G; Schwartz SM; Hazra A; Tanaka T; Vermeulen SH; Cotlarciuc I; Yuan X; Malarstig A; Bandinelli S; Bis JC; Morn H; Brown MJ; Chen C; Chen Y-D; Clarke RJ; Dehghan A; Erdmann J; Ferrucci L; Hamsten A; Hofman A; Hunten DJ; Goel A; Johnson AD; Kathiresan S; Kampman E; Kiel DP; Kiemeney LA; Chambers JC; Kraft P; Lindemans J; McKnight B; Nelson CP; O'Donnell CJ; Psaty BM; Ridken PM; Rivadeneira F; Rose LM; Seedoif U; Siscovick DS; Schunkert H; Selhub J; Ueland PM; Vollenweiden P; Waeben G; Waterworth DM; Watkins H; Witteman JCM; den Heijen M; Jacques P; Uitterlinden AG; Koonet JS; Rader DJ; Reilly MP; Moose V; Chasman DI; Samani NJ; Ahmadi KR
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(9):2273-2279
Progression of Carotid Intima-Media Thickness as Predictor of Vascular Events Results from the IMPROVE Study
Baldassarre D; Veglia F; Hamsten A; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Grossi E; Paoletti R; Tremoli E
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(9):2267-2272
Multilocus Genetic Risk Scores for Coronary Heart Disease Prediction
Ganna A; Magnusson PKE; Pedersen NL; de Faire U; Reilly M; Arnloe J; Sundstrom J; Hamsten A; Ingelsson E
Article: PLOS GENETICS. 2013;9(6):e1003500
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Randall JC; Winkler TW; Kutalik Z; Berndt SI; Jackson AU; Monda KL; Kilpelaeinen TO; Esko T; Maegi R; Li S; Workalemahu T; Feitosa MF; Croteau-Chonka DC; Day FR; Fall T; Ferreira T; Gustafsson S; Locke AE; Mathieson I; Scherag A; Vedantam S; Wood AR; Liang L; Steinthorsdottir V; Thorleifsson G; Dermitzakis ET; Dimas AS; Karpe F; Min JL; Nicholson G; Clegg DJ; Person T; Krohn JP; Bauer S; Buechler C; Eisinger K; Bonnefond A; Froguel P; Hottenga J-J; Prokopenko I; Waite LL; Harris TB; Smith AV; Shuldiner AR; McArdle WL; Caulfield MJ; Munroe PB; Gronberg H; Chen Y-DI; Li G; Beckmann JS; Johnson T; Thorsteinsdottir U; Teder-Laving M; Khaw K-T; Wareham NJ; Zhao JH; Amin N; Oostra BA; Kraja AT; Province MA; Cupples LA; Heard-Costa NL; Kaprio J; Ripatti S; Surakka I; Collins FS; Saramies J; Tuomilehto J; Jula A; Salomaa V; Erdmann J; Hengstenberg C; Loley C; Schunkert H; Lamina C; Wichmann HE; Albrecht E; Gieger C; Hicks AA; Johansson A; Pramstaller PP; Kathiresan S; Speliotes EK; Penninx B; Hartikainen A-L; Jarvelin M-R; Gyllensten U; Boomsma DI; Campbell H; Wilson JF; Chanock SJ; Farrall M; Goel A; Medina-Gomez C; Rivadeneira F; Estrada K; Uitterlinden AG; Hofman A; Zillikens MC; den Heijer M; Kiemeney LA; Maschio A; Hall P; Tyrer J; Teumer A; Voelzke H; Kovacs P; Toenjes A; Mangino M; Spector TD; Hayward C; Rudan I; Hall AS; Samani NJ; Attwood AP; Sambrook JG; Hung J; Palmer LJ; Lokki M-L; Sinisalo J; Boucher G; Huikuri H; Lorentzon M; Ohlsson C; Eklund N; Eriksson JG; Barlassina C; Rivolta C; Nolte IM; Snieder H; Van der Klauw MM; Van Vliet-Ostaptchouk JV; Gejman PV; Shi J; Jacobs KB; Wang Z; Bakker SJL; Leach IM; Navis G; van der Harst P; Martin NG; Medland SE; Montgomery GW; Yang J; Chasman DI; Ridker PM; Rose LM; Lehtimaki T; Raitakari O; Absher D; Iribarren C; Basart H; Hovingh KG; Hyppoenen E; Power C; Anderson D; Beilby JP; Hui J; Jolley J; Sager H; Bornstein SR; Schwarz PEH; Kristiansson K; Perola M; Lindstrom J; Swift AJ; Uusitupa M; Atalay M; Lakka TA; Rauramaa R; Bolton JL; Fowkes G; Fraser RM; Price JF; Fischer K; KrjutAikov K; Metspalu A; Mihailov E; Langenberg C; Luan J; Ong KK; Chines PS; Keinanen-Kiukaanniemi SM; Saaristo TE; Edkins S; Franks PW; Hallmans G; Shungin D; Morris AD; Palmer CNA; Erbel R; Moebus S; Noethen MM; Pechlivanis S; Hveem K; Narisu N; Hamsten A; Humphries SE; Strawbridge RJ; Tremoli E; Grallert H; Thorand B; Illig T; Koenig W; Mueller-Nurasyid M; Peters A; Boehm BO; Kleber ME; Maerz W; Winkelmann BR; Kuusisto J; Laakso M; Arveiler D; Cesana G; Kuulasmaa K; Virtamo J; Yarnell JWG; Kuh D; Wong A; Lind L; de Faire U; Gigante B; Magnusson PKE; Pedersen NL; Dedoussis G; Dimitriou M; Kolovou G; Kanoni S; Stirrups K; Bonnycastle LL; Njolstad I; Wilsgaard T; Ganna A; Rehnberg E; Hingorani A; Kivimaki M; Kumari M; Assimes TL; Barroso IS; Boehnke M; Borecki IB; Deloukas P; Fox CS; Frayling T; Groop LC; Haritunians T; Hunter D; Ingelsson E; Kaplan R; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Abecasis GR; McCarthy MI; Hirschhorn JN; Qi L; Loos RJF; Lindgren CM; North KE; Heid IM
Article: NATURE GENETICS. 2013;45(5):501-U69
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
Berndt SI; Gustafsson S; Maegi R; Ganna A; Wheeler E; Feitosa MF; Justice AE; Monda KL; Croteau-Chonka DC; Day FR; Esko T; Fall T; Ferreira T; Gentilini D; Jackson AU; Luan J; Randall JC; Vedantam S; Willer CJ; Winkler TW; Wood AR; Workalemahu T; Hu Y-J; Lee SH; Liang L; Lin D-Y; Min JL; Neale BM; Thorleifsson G; Yang J; Albrecht E; Amin N; Bragg-Gresham JL; Cadby G; den Heijer M; Eklund N; Fischer K; Goel A; Hottenga J-J; Huffman JE; Jarick I; Johansson A; Johnson T; Kanoni S; Kleber ME; Koenig IR; Kristiansson K; Kutalik Z; Lamina C; Lecoeur C; Li G; Mangino M; McArdle WL; Medina-Gomez C; Mueller-Nurasyid M; Ngwa JS; Nolte IM; Paternoster L; Pechlivanis S; Perola M; Peters MJ; Preuss M; Rose LM; Shi J; Shungin D; Smith AV; Strawbridge RJ; Surakka I; Teumer A; Trip MD; Tyrer J; Van Vliet-Ostaptchouk JV; Vandenput L; Waite LL; Zhao JH; Absher D; Asselbergs FW; Atalay M; Attwood AP; Balmforth AJ; Basart H; Beilby J; Bonnycastle LL; Brambilla P; Bruinenberg M; Campbell H; Chasman DI; Chines PS; Collins FS; Connell JM; Cookson WO; de Faire U; de Vegt F; Dei M; Dimitriou M; Edkins S; Estrada K; Evans DM; Farrall M; Ferrario MM; Ferrieres J; Franke L; Frau F; Gejman PV; Grallert H; Groenberg H; Gudnason V; Hall AS; Hall P; Hartikainen A-L; Hayward C; Heard-Costa NL; Heath AC; Hebebrand J; Homuth G; Hu FB; Hunt SE; Hyppoenen E; Iribarren C; Jacobs KB; Jansson J-O; Jula A; Kahonen M; Kathiresan S; Kee F; Khaw K-T; Kivimaki M; Koenig W; Kraja AT; Kumari M; Kuulasmaa K; Kuusisto J; Laitinen JH; Lakka TA; Langenberg C; Launer LJ; Lind L; Lindstrom J; Liu J; Liuzzi A; Lokki M-L; Lorentzon M; Madden PA; Magnusson PK; Manunta P; Marek D; Maerz W; Leach IM; McKnight B; Medland SE; Mihailov E; Milani L; Montgomery GW; Mooser V; Muehleisen TW; Munroe PB; Musk AW; Narisu N; Navis G; Nicholson G; Nohr EA; Ong KK; Oostra BA; Palmer CNA; Palotie A; Peden JF; Pedersen N; Peters A; Polasek O; Pouta A; Pramstaller PP; Prokopenko I; Puetter C; Radhakrishnan A; Raitakari O; Rendon A; Rivadeneira F; Rudan I; Saaristo TE; Sambrook JG; Sanders AR; Sanna S; Saramies J; Schipf S; Schreiber S; Schunkert H; Shin S-Y; Signorini S; Sinisalo J; Skrobek B; Soranzo N; Stancakova A; Stark K; Stephens JC; Stirrups K; Stolk RP; Stumvoll M; Swift AJ; Theodoraki EV; Thorand B; Tregouet D-A; Tremoli E; Van der Klauw MM; van Meurs JBJ; Vermeulen SH; Viikari J; Virtamo J; Vitart V; Waeber G; Wang Z; Widen E; Wild SH; Willemsen G; Winkelmann BR; Witteman JCM; Wolffenbuttel BHR; Wong A; Wright AF; Zillikens MC; Amouyel P; Boehm BO; Boerwinkle E; Boomsma DI; Caulfield MJ; Chanock SJ; Cupples LA; Cusi D; Dedoussis GV; Erdmann J; Eriksson JG; Franks PW; Froguel P; Gieger C; Gyllensten U; Hamsten A; Harris TB; Hengstenberg C; Hicks AA; Hingorani A; Hinney A; Hofman A; Hovingh KG; Hveem K; Illig T; Jarvelin M-R; Joeckel K-H; Keinanen-Kiukaanniemi SM; Kiemeney LA; Kuh D; Laakso M; Lehtimaki T; Levinson DF; Martin NG; Metspalu A; Morris AD; Nieminen MS; Njolstad I; Ohlsson C; Oldehinkel AJ; Ouwehand WH; Palmer LJ; Penninx B; Power C; Province MA; Psaty BM; Qi L; Rauramaa R; Ridker PM; Ripatti S; Salomaa V; Samani NJ; Snieder H; Sorensen TIA; Spector TD; Stefansson K; Tonjes A; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Vollenweider P; Wallaschofski H; Wareham NJ; Watkins H; Wichmann H-E; Wilson JF; Abecasis GR; Assimes TL; Barroso I; Boehnke M; Borecki IB; Deloukas P; Fox CS; Frayling T; Groop LC; Haritunian T; Heid IM; Hunter D; Kaplan RC; Karpe F; Moffatt MF; Mohlke KL; O'Connell JR; Pawitan Y; Schadt EE; Schlessinger D; Steinthorsdottir V; Strachan DP; Thorsteinsdottir U; van Duijn CM; Visscher PM; Di Blasio AM; Hirschhorn JN; Lindgren CM; Morris AP; Meyre D; Scherag A; McCarthy MI; Speliotes EK; North KE; Loos RJF; Ingelsson E
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2013;33(5):1063-1069
Identification of a Functional Apolipoprotein E Promoter Polymorphism Regulating Plasma Apolipoprotein E Concentration
Mannila MN; Mahdessian H; Franco-Cereceda A; Eggertsen G; de Faire U; Syvanen A-C; Eriksson P; Hamsten A; van 't Hooft FM
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2013;11(3):521-528
Genetic determinants of plasma β₂-glycoprotein I levels: a genome-wide association study in extended pedigrees from Spain
Athanasiadis G; Sabater-Lleal M; Buil A; Souto JC; Borrell M; Lathrop M; Watkins H; Almasy L; Hamsten A; Soria JM
Article: ATHEROSCLEROSIS. 2013;226(2):440-446
A gene-centric study of common carotid artery remodelling
Harrison SC; Zabaneh D; Asselbergs FW; Drenos F; Jones GT; Shah S; Gertow K; Sennblad B; Strawbridge RJ; Gigante B; Holewijn S; De Graaf J; Vermeulen S; Folkersen L; van Rij AM; Baldassarre D; Veglia F; Talmud PJ; Deanfield JE; Agu O; Kivimaki M; Kumari M; Bown MJ; Nyyssonen K; Rauramaa R; Smit AJ; Franco-Cereceda A; Giral P; Mannarino E; Silveira A; Syvanen A-C; de Borst GJ; van der Graaf Y; de Faire U; Baas AF; Blankensteijn JD; Wareham NJ; Fowkes G; Tzoulaki I; Price JF; Tremoli E; Hingorani AD; Eriksson P; Hamsten A; Humphries SE
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2013;6(1):63-72
Causal Relevance of Blood Lipid Fractions in the Development of Carotid Atherosclerosis Mendelian Randomization Analysis
Shah S; Casas J-P; Drenos F; Whittaker J; Deanfield J; Swerdlow DI; Holmes MV; Kivimaki M; Langenberg C; Wareham N; Gertow K; Sennblad B; Strawbridge RJ; Baldassarre D; Veglia F; Tremoli E; Gigante B; de Faire U; Kumari M; Talmud PJ; Hamsten A; Humphries SE; Hingorani AD
Article: NATURE GENETICS. 2013;45(1):25-33
Large-scale association analysis identifies new risk loci for coronary artery disease.
CARDIoGRAMplusC4D Consortium; Deloukas P; Kanoni S; Willenborg C; Farrall M; Assimes TL; Thompson JR; Ingelsson E; Saleheen D; Erdmann J; Goldstein BA; Stirrups K; König IR; Cazier J-B; Johansson A; Hall AS; Lee J-Y; Willer CJ; Chambers JC; Esko T; Folkersen L; Goel A; Grundberg E; Havulinna AS; Ho WK; Hopewell JC; Eriksson N; Kleber ME; Kristiansson K; Lundmark P; Lyytikäinen L-P; Rafelt S; Shungin D; Strawbridge RJ; Thorleifsson G; Tikkanen E; Van Zuydam N; Voight BF; Waite LL; Zhang W; Ziegler A; Absher D; Altshuler D; Balmforth AJ; Barroso I; Braund PS; Burgdorf C; Claudi-Boehm S; Cox D; Dimitriou M; Do R; DIAGRAM Consortium; CARDIOGENICS Consortium; Doney ASF; El Mokhtari N; Eriksson P; Fischer K; Fontanillas P; Franco-Cereceda A; Gigante B; Groop L; Gustafsson S; Hager J; Hallmans G; Han B-G; Hunt SE; Kang HM; Illig T; Kessler T; Knowles JW; Kolovou G; Kuusisto J; Langenberg C; Langford C; Leander K; Lokki M-L; Lundmark A; McCarthy MI; Meisinger C; Melander O; Mihailov E; Maouche S; Morris AD; Müller-Nurasyid M; MuTHER Consortium; Nikus K; Peden JF; Rayner NW; Rasheed A; Rosinger S; Rubin D; Rumpf MP; Schäfer A; Sivananthan M; Song C; Stewart AFR; Tan S-T; Thorgeirsson G; van der Schoot CE; Wagner PJ; Wellcome Trust Case Control Consortium; Wells GA; Wild PS; Yang T-P; Amouyel P; Arveiler D; Basart H; Boehnke M; Boerwinkle E; Brambilla P; Cambien F; Cupples AL; de Faire U; Dehghan A; Diemert P; Epstein SE; Evans A; Ferrario MM; Ferrières J; Gauguier D; Go AS; Goodall AH; Gudnason V; Hazen SL; Holm H; Iribarren C; Jang Y; Kähönen M; Kee F; Kim H-S; Klopp N; Koenig W; Kratzer W; Kuulasmaa K; Laakso M; Laaksonen R; Lee J-Y; Lind L; Ouwehand WH; Parish S; Park JE; Pedersen NL; Peters A; Quertermous T; Rader DJ; Salomaa V; Schadt E; Shah SH; Sinisalo J; Stark K; Stefansson K; Trégouët D-A; Virtamo J; Wallentin L; Wareham N; Zimmermann ME; Nieminen MS; Hengstenberg C; Sandhu MS; Pastinen T; Syvänen A-C; Hovingh GK; Dedoussis G; Franks PW; Lehtimäki T; Metspalu A; Zalloua PA; Siegbahn A; Schreiber S; Ripatti S; Blankenberg SS; Perola M; Clarke R; Boehm BO; O'Donnell C; Reilly MP; März W; Collins R; Kathiresan S; Hamsten A; Kooner JS; Thorsteinsdottir U; Danesh J; Palmer CNA; Roberts R; Watkins H; Schunkert H; Samani NJ
Article: PLOS GENETICS. 2013;9(7):e1003607
Gene x Physical Activity Interactions in Obesity: Combined Analysis of 111,421 Individuals of European Ancestry
Ahmad S; Rukh G; Varga TV; Ali A; Kurbasic A; Shungin D; Ericson U; Koivula RW; Chu AY; Rose LM; Ganna A; Qi Q; Stancakova A; Sandholt CH; Elks CE; Curhan G; Jensen MK; Tamimi RM; Allin KH; Jorgensen T; Brage S; Langenberg C; Aadahl M; Grarup N; Linneberg A; Pare G; Magnusson PKE; Pedersen NL; Boehnke M; Hamsten A; Mohlke KL; Pasquale LT; Pedersen O; Scott RA; Ridker PM; Ingelsson E; Laakso M; Hansen T; Qi L; Wareham NJ; Chasman DI; Hallmans G; Hu FB; Renstrom F; Orho-Melander M; Franks PW
Article: PLOS ONE. 2013;8(3):e60454
Genetic Variants from Lipid-Related Pathways and Risk for Incident Myocardial Infarction
Song C; Pedersen NL; Reynolds CA; Sabater-Lleal M; Kanoni S; Willenborg C; Syvanen A-C; Watkins H; Hamsten A; Prince JA; Ingelsson E
Article: PLOS ONE. 2013;8(12):e83122
Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease
Maubaret CG; Salpea KD; Romanoski CE; Folkersen L; Cooper JA; Stephanou C; Li KW; Palmen J; Hamsten A; Neil A; Stephens JW; Lusis AJ; Eriksson P; Talmud PJ; Humphries SE
Article: BLOOD. 2012;120(24):4873-4881
Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation
Huang J; Sabater-Lleal M; Asselbergs FW; Tregouet D; Shin S-Y; Ding J; Baumert J; Oudot-Mellakh T; Folkersen L; Johnson AD; Smith NL; Williams SM; Ikram MA; Kleber ME; Becker DM; Vinh T; Mychaleckyj JC; Tang W; Yang Q; Sennblad B; Moore JH; Williams FMK; Dehghan A; Silbernagel G; Schrijvers EMC; Smith S; Karakas M; Tofler GH; Silveira A; Navis GJ; Lohman K; Chen M-H; Peters A; Goel A; Hopewell JC; Chambers JC; Saleheen D; Lundmark P; Psaty BM; Strawbridge RJ; Boehm BO; Carter AM; Meisinger C; Peden JF; Bis JC; McKnight B; Ohrvik J; Taylor K; Franzosi MG; Seedorf U; Collins R; Franco-Cereceda A; Syvaenen A-C; Goodall AH; Yanek LR; Cushman M; Mueller-Nurasyid M; Folsom AR; Basu S; Matijevic N; van Gilst WH; Kooner JS; Hofman A; Danesh J; Clarke R; Meigs JB; Kathiresan S; Reilly MP; Klopp N; Harris TB; Winkelmann BR; Grant PJ; Hillege HL; Watkins H; Spector TD; Becker LC; Tracy RP; Maerz W; Uitterlinden AG; Eriksson P; Cambien F; Morange P-E; Koenig W; Soranzo N; van der Harst P; Liu Y; O'Donnell CJ; Hamsten A
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665
Identification of the BCAR1-CFDP1-TMEM170A Locus as a Determinant of Carotid Intima-Media Thickness and Coronary Artery Disease Risk
Gertow K; Sennblad B; Strawbridge RJ; Oehrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimaeki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikstrom M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssonen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvanen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: ATHEROSCLEROSIS. 2012;225(1):231-236
LDL oxidative modification and carotid atherosclerosis: Results of a multicenter study
Nyyssonen K; Kurl S; Karppi J; Nurmi T; Baldassarre D; Veglia F; Rauramaa R; de Faire U; Hamsten A; Smit AJ; Mannarino E; Humphries SE; Giral P; Grossi E; Tremoli E
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2012;60(16):1489-1499
Measurements of Carotid Intima-Media Thickness and of Interadventitia Common Carotid Diameter Improve Prediction of Cardiovascular Events Results of the IMPROVE (Carotid Intima Media Thickness [IMT] and IMT-Progression as Predictors of Vascular Events in a High Risk European Population) Study
Baldassarre D; Hamsten A; Veglia F; de Faire U; Humphries SE; Smit AJ; Giral P; Kurl S; Rauramaa R; Mannarino E; Grossi E; Paoletti R; Tremoli E
Article: NATURE. 2012;490(7419):267-272
FTO genotype is associated with phenotypic variability of body mass index
Yang J; Loos RJF; Powell JE; Medland SE; Speliotes EK; Chasman DI; Rose LM; Thorleifsson G; Steinthorsdottir V; Maegi R; Waite L; Smith AV; Yerges-Armstrong LM; Monda KL; Hadley D; Mahajan A; Li G; Kapur K; Vitart V; Huffman JE; Wang SR; Palmer C; Esko T; Fischer K; Zhao JH; Demirkan A; Isaacs A; Feitosa MF; Luan J; Heard-Costa NL; White C; Jackson AU; Preuss M; Ziegler A; Eriksson J; Kutalik Z; Frau F; Nolte IM; Van Vliet-Ostaptchouk JV; Hottenga J-J; Jacobs KB; Verweij N; Goel A; Medina-Gomez C; Estrada K; Bragg-Gresham JL; Sanna S; Sidore C; Tyrer J; Teumer A; Prokopenko I; Mangino M; Lindgren CM; Assimes TL; Shuldiner AR; Hui J; Beilby JP; McArdle WL; Hall P; Haritunians T; Zgaga L; Kolcic I; Polasek O; Zemunik T; Oostra BA; Junttila MJ; Groenberg H; Schreiber S; Peters A; Hicks AA; Stephens J; Foad NS; Laitinen J; Pouta A; Kaakinen M; Willemsen G; Vink JM; Wild SH; Navis G; Asselbergs FW; Homuth G; John U; Iribarren C; Harris T; Launer L; Gudnason V; O'Connell JR; Boerwinkle E; Cadby G; Palmer LJ; James AL; Musk AW; Ingelsson E; Psaty BM; Beckmann JS; Waeber G; Vollenweider P; Hayward C; Wright AF; Rudan I; Groop LC; Metspalu A; Khaw KT; van Duijn CM; Borecki IB; Province MA; Wareham NJ; Tardif J-C; Huikuri HV; Cupples LA; Atwood LD; Fox CS; Boehnke M; Collins FS; Mohlke KL; Erdmann J; Schunkert H; Hengstenberg C; Stark K; Lorentzon M; Ohlsson C; Cusi D; Staessen JA; Van der Klauw MM; Pramstaller PP; Kathiresan S; Jolley JD; Ripatti S; Jarvelin M-R; de Geus EJC; Boomsma DI; Penninx B; Wilson JF; Campbell H; Chanock SJ; van der Harst P; Hamsten A; Watkins H; Hofman A; Witteman JC; Zillikens MC; Uitterlinden AG; Rivadeneira F; Zillikens MC; Kiemeney LA; Vermeulen SH; Abecasis GR; Schlessinger D; Schipf S; Stumvoll M; Toenjes A; Spector TD; North KE; Lettre G; McCarthy MI; Berndt SI; Heath AC; Madden PAF; Nyholt DR; Montgomery GW; Martin NG; McKnight B; Strachan DP; Hill WG; Snieder H; Ridker PM; Thorsteinsdottir U; Stefansson K; Frayling TM; Hirschhorn JN; Goddard ME; Visscher PM
Article: NATURE GENETICS. 2012;44(9):991-1005
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Scott RA; Lagou V; Welch RP; Wheeler E; Montasser ME; Luan J; Maegi R; Strawbridge RJ; Rehnberg E; Gustafsson S; Kanoni S; Rasmussen-Torvik LJ; Yengo L; Lecoeur C; Shungin D; Sanna S; Sidore C; Johnson PCD; Jukema JW; Johnson T; Mahajan A; Verweij N; Thorleifsson G; Hottenga J-J; Shah S; Smith AV; Sennblad B; Gieger C; Salo P; Perola M; Timpson NJ; Evans DM; St Pourcain B; Wu Y; Andrews JS; Hui J; Bielak LF; Zhao W; Horikoshi M; Navarro P; Isaacs A; O'Connell JR; Stirrups K; Vitart V; Hayward C; Esko T; Mihailov E; Fraser RM; Fall T; Voight BF; Raychaudhuri S; Chen H; Lindgren CM; Morris AP; Rayner NW; Robertson N; Rybin D; Liu C-T; Beckmann JS; Willems SM; Chines PS; Jackson AU; Kang HM; Stringham HM; Song K; Tanaka T; Peden JF; Goel A; Hicks AA; An P; Mueller-Nurasyid M; Franco-Cereceda A; Folkersen L; Marullo L; Jansen H; Oldehinkel AJ; Bruinenberg M; Pankow JS; North KE; Forouhi NG; Loos RJF; Edkins S; Varga TV; Hallmans G; Oksa H; Antonella M; Nagaraja R; Trompet S; Ford I; Bakker SJL; Kong A; Kumari M; Gigante B; Herder C; Munroe PB; Caulfield M; Antti J; Mangino M; Small K; Miljkovic I; Liu Y; Atalay M; Kiess W; James AL; Rivadeneira F; Uitterlinden AG; Palmer CNA; Doney ASF; Willemsen G; Smit JH; Campbell S; Polasek O; Bonnycastle LL; Hercberg S; Dimitriou M; Bolton JL; Fowkes GR; Kovacs P; Lindstrom J; Zemunik T; Bandinelli S; Wild SH; Basart HV; Rathmann W; Grallert H; Maerz W; Kleber ME; Boehm BO; Peters A; Pramstaller PP; Province MA; Borecki IB; Hastie ND; Rudan I; Campbell H; Watkins H; Farrall M; Stumvoll M; Ferrucci L; Waterworth DM; Bergman RN; Collins FS; Tuomilehto J; Watanabe RM; de Geus EJC; Penninx BW; Hofman A; Oostra BA; Psaty BM; Vollenweider P; Wilson JF; Wright AF; Hovingh GK; Metspalu A; Uusitupa M; Magnusson PKE; Kyvik KO; Kaprio J; Price JF; Dedoussis GV; Deloukas P; Meneton P; Lind L; Boehnke M; Shuldiner AR; van Duijn CM; Morris AD; Toenjes A; Peyser PA; Beilby JP; Koerner A; Kuusisto J; Laakso M; Bornstein SR; Schwarz PEH; Lakka TA; Rauramaa R; Adair LS; Smith GD; Spector TD; Illig T; de Faire U; Hamsten A; Gudnason V; Kivimaki M; Hingorani A; Keinanen-Kiukaanniemi SM; Saaristo TE; Boomsma DI; Stefansson K; van der Harst P; Dupuis J; Pedersen NL; Sattar N; Harris TB; Cucca F; Ripatti S; Salomaa V; Mohlke KL; Balkau B; Froguel P; Pouta A; Jarvelin M-R; Wareham NJ; Bouatia-Naji N; McCarthy MI; Franks PW; Meigs JB; Teslovich TM; Florez JC; Langenberg C; Ingelsson E; Prokopenko I; Barroso I
Article: NATURE GENETICS. 2012;44(9):981-990
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Morris AP; Voight BF; Teslovich TM; Ferreira T; Segre AV; Steinthorsdottir V; Strawbridge RJ; Khan H; Grallert H; Mahajan A; Prokopenko I; Kang HM; Dina C; Esko T; Fraser RM; Kanoni S; Kumar A; Lagou V; Langenberg C; Luan J; Lindgren CM; Mueller-Nurasyid M; Pechlivanis S; Rayner NW; Scott LJ; Wiltshire S; Yengo L; Kinnunen L; Rossin EJ; Raychaudhuri S; Johnson AD; Dimas AS; Loos RJF; Vedantam S; Chen H; Florez JC; Fox C; Liu C-T; Rybin D; Couper DJ; Kao WHL; Li M; Cornelis MC; Kraft P; Sun Q; van Dam RM; Stringham HM; Chines PS; Fischer K; Fontanillas P; Holmen OL; Hunt SE; Jackson AU; Kong A; Lawrence R; Meyer J; Perry JRB; Platou CGP; Potter S; Rehnberg E; Robertson N; Sivapalaratnam S; Stancakova A; Stirrups K; Thorleifsson G; Tikkanen E; Wood AR; Almgren P; Atalay M; Benediktsson R; Bonnycastle LL; Burtt N; Carey J; Charpentier G; Crenshaw AT; Doney ASF; Dorkhan M; Edkins S; Emilsson V; Eury E; Forsen T; Gertow K; Gigante B; Grant GB; Groves CJ; Guiducci C; Herder C; Hreidarsson AB; Hui J; James A; Jonsson A; Rathmann W; Klopp N; Kravic J; Krjutskov K; Langford C; Leander K; Lindholm E; Lobbens S; Mannisto S; Mirza G; Muehleisen TW; Musk B; Parkin M; Rallidis L; Saramies J; Sennblad B; Shah S; Sigurdsson G; Silveira A; Steinbach G; Thorand B; Trakalo J; Veglia F; Wennauer R; Winckler W; Zabaneh D; Campbell H; van Duijn C; Uitterlinden AG; Hofman A; Sijbrands E; Abecasis GR; Owen KR; Zeggini E; Trip MD; Forouhi NG; Syvanen A-C; Eriksson JG; Peltonen L; Noethen MM; Balkau B; Palmer CNA; Lyssenko V; Tuomi T; Isomaa B; Hunter DJ; Qi L; Shuldiner AR; Roden M; Barroso I; Wilsgaard T; Beilby J; Hovingh K; Price JF; Wilson JF; Rauramaa R; Lakka TA; Lind L; Dedoussis G; Njolstad I; Pedersen NL; Khaw K-T; Wareham NJ; Keinanen-Kiukaanniemi SM; Saaristo TE; Korpi-Hyovalti E; Saltevo J; Laakso M; Kuusisto J; Metspalu A; Collins FS; Mohlke KL; Bergman RN; Tuomilehto J; Boehm BO; Gieger C; Hveem K; Cauchi S; Froguel P; Baldassarre D; Tremoli E; Humphries SE; Saleheen D; Danesh J; Ingelsson E; Ripatti S; Salomaa V; Erbel R; Joeckel K-H; Moebus S; Peters A; Illig T; de Faire U; Hamsten A; Morris AD; Donnelly PJ; Frayling TM; Hattersley AT; Boerwinkle E; Melander O; Kathiresan S; Nilsson PM; Deloukas P; Thorsteinsdottir U; Groop LC; Stefansson K; Hu F; Pankow JS; Dupuis J; Meigs JB; Altshuler D; Boehnke M; McCarthy MI
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2012;60(8):722-729
Apolipoprotein(a) Genetic Sequence Variants Associated With Systemic Atherosclerosis and Coronary Atherosclerotic Burden But Not With Venous Thromboembolism
Helgadottir A; Gretarsdottir S; Thorleifsson G; Holm H; Patel RS; Gudnason T; Jones GT; van Rij AM; Eapen DJ; Baas AF; Tregouet D-A; Morange P-E; Emmerich J; Lindblad B; Gottsater A; Kiemeny LA; Lindholt JS; Sakalihasan N; Ferrell RE; Carey DJ; Elmore JR; Tsao PS; Grarup N; Jorgensen T; Witte DR; Hansen T; Pedersen O; Pola R; Gaetani E; Magnadottir HB; Wijmenga C; Tromp G; Ronkainen A; Ruigrok YM; Blankensteijn JD; Mueller T; Wells PS; Corral J; Manuel Soria J; Carlos Souto J; Peden JF; Jalilzadeh S; Mayosi BM; Keavney B; Strawbridge RJ; Sabater-Lleal M; Gertow K; Baldassarre D; Nyyssonen K; Rauramaa R; Smit AJ; Mannarino E; Giral P; Tremoli E; de Faire U; Humphries SE; Hamsten A; Haraldsdottir V; Olafsson I; Magnusson MK; Samani NJ; Levey AI; Markus HS; Kostulas K; Dichgans M; Berger K; Kuhlenbaeumer G; Ringelstein EB; Stoll M; Seedorf U; Rothwell PM; Powell JT; Kuivaniemi H; Onundarson PT; Valdimarsson E; Matthiasson SE; Gudbjartsson DF; Thorgeirsson G; Quyyumi AA; Watkins H; Farrall M; Thorsteinsdottir U; Stefansson K
Article: THROMBOSIS RESEARCH. 2012;130(2):221-225
Relationships of plasma factor VIIa-antithrombin complexes to manifest and future cardiovascular disease
Silveira A; Scanavini D; Boquist S; Ericsson C-G; Hellenius M-L; Leander K; de Faire U; Ohrvik J; Woodhams B; Morrissey JH; Hamsten A
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2012;30(2):288-294
Serine protease inhibitor A3 in atherosclerosis and aneurysm disease
Wagsater D; Johansson D; Fontaine V; Vorkapic E; Backlund A; Razuvaev A; Mayranpaa MI; Hjerpe C; Caidahl K; Hamsten A; Franco-Cereceda A; Wilbertz J; Swedenborg J; Zhou X; Eriksson P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2012;32(8):2008-2016
A Genome-Wide Association Study Identifies KNG1 as a Genetic Determinant of Plasma Factor XI Level and Activated Partial Thromboplastin Time
Sabater-Lleal M; Martinez-Perez A; Buil A; Folkersen L; Carlos Souto J; Bruzelius M; Borrell M; Odeberg J; Silveira A; Eriksson P; Almasy L; Hamsten A; Manuel Soria J
Article: ATHEROSCLEROSIS. 2012;223(1):223-229
Serum 25-hydroxyvitamin D concentration, established and emerging cardiovascular risk factors and risk of myocardial infarction before the age of 60 years
Deleskog A; Piksasova O; Silveira A; Samnegard A; Tornvall P; Eriksson P; Gustafsson S; Ostenson C-G; Ohrvik J; Hamsten A
Article: DIABETOLOGIA. 2012;55(6):1668-1678
Low serum 25-hydroxyvitamin D level predicts progression to type 2 diabetes in individuals with prediabetes but not with normal glucose tolerance
Deleskog A; Hilding A; Brismar K; Hamsten A; Efendic S; Ostenson C-G
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2012;32(6):1526-1534
Common and Low-Frequency Genetic Variants in the PCSK9 Locus Influence Circulating PCSK9 Levels
Chernogubova E; Strawbridge R; Mahdessian H; Malarstig A; Krapivner S; Gigante B; Hellenius M-L; de Faire U; Franco-Cereceda A; Syvaenen A-C; Troutt JS; Konrad RJ; Eriksson P; Hamsten A; van 't Hooft FM
Article: NATURE GENETICS. 2012;44(6):659-U81
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
Manning AK; Hivert M-F; Scott RA; Grimsby JL; Bouatia-Naji N; Chen H; Rybin D; Liu C-T; Bielak LF; Prokopenko I; Amin N; Barnes D; Cadby G; Hottenga J-J; Ingelsson E; Jackson AU; Johnson T; Kanoni S; Ladenvall C; Lagou V; Lahti J; Lecoeur C; Liu Y; Martinez-Larrad MT; Montasser ME; Navarro P; Perry JRB; Rasmussen-Torvik LJ; Salo P; Sattar N; Shungin D; Strawbridge RJ; Tanaka T; van Duijn CM; An P; de Andrade M; Andrews JS; Aspelund T; Atalay M; Aulchenko Y; Balkau B; Bandinelli S; Beckmann JS; Beilby JP; Bellis C; Bergman RN; Blangero J; Boban M; Boehnke M; Boerwinkle E; Bonnycastle LL; Boomsma DI; Borecki IB; Boettcher Y; Bouchard C; Brunner E; Budimir D; Campbell H; Carlson O; Chines PS; Clarke R; Collins FS; Corbaton-Anchuelo A; Couper D; de Faire U; Dedoussis GV; Deloukas P; Dimitriou M; Egan JM; Eiriksdottir G; Erdos MR; Eriksson JG; Eury E; Ferrucci L; Ford I; Forouhi NG; Fox CS; Franzosi MG; Franks PW; Frayling TM; Froguel P; Galan P; de Geus E; Gigante B; Glazer NL; Goel A; Groop L; Gudnason V; Hallmans G; Hamsten A; Hansson O; Harris TB; Hayward C; Heath S; Hercberg S; Hicks AA; Hingorani A; Hofman A; Hui J; Hung J; Jarvelin M-R; Jhun MA; Johnson PCD; Jukema JW; Jula A; Kao WH; Kaprio J; Kardia SLR; Keinanen-Kiukaanniemi S; Kivimaki M; Kolcic I; Kovacs P; Kumari M; Kuusisto J; Kyvik KO; Laakso M; Lakka T; Lannfelt L; Lathrop GM; Launer LJ; Leander K; Li G; Lind L; Lindstrom J; Lobbens S; Loos RJF; Luan J; Lyssenko V; Magi R; Magnusson PKE; Marmot M; Meneton P; Mohlke KL; Mooser V; Morken MA; Miljkovic I; Narisu N; O'Connell J; Ong KK; Oostra BA; Palmer LJ; Palotie A; Pankow JS; Peden JF; Pedersen NL; Pehlic M; Peltonen L; Penninx B; Pericic M; Perola M; Perusse L; Peyser PA; Polasek O; Pramstaller PP; Province MA; Raikkonen K; Rauramaa R; Rehnberg E; Rice K; Rotter JI; Rudan I; Ruokonen A; Saaristo T; Sabater-Lleal M; Salomaa V; Savage DB; Saxena R; Schwarz P; Seedorf U; Sennblad B; Serrano-Rios M; Shuldiner AR; Sijbrands EJG; Siscovick DS; Smit JH; Small KS; Smith NL; Smith AV; Stancakova A; Stirrups K; Stumvoll M; Sun YV; Swift AJ; Toenjes A; Tuomilehto J; Trompet S; Uitterlinden AG; Uusitupa M; Vikstrom M; Vitart V; Vohl M-C; Voight BF; Vollenweider P; Waeber G; Waterworth DM; Watkins H; Wheeler E; Widen E; Wild SH; Willems SM; Willemsen G; Wilson JF; Witteman JCM; Wright AF; Yaghootkar H; Zelenika D; Zemunik T; Zgaga L; Wareham NJ; McCarthy MI; Barroso I; Watanabe RM; Florez JC; Dupuis J; Meigs JB; Langenberg C
Article: CLINICA CHIMICA ACTA. 2012;413(7-8):727-732
NAMPT (visfatin) and AKT1 genetic variants associate with myocardial infarction
Leander K; Gigante B; Silveira A; Vikstrom M; Hamsten A; Hogberg J
Article: EUROPEAN HEART JOURNAL. 2012;33(7):881-888
Association of a sequence variant in DAB2IP with coronary heart disease
Harrison SC; Cooper JA; Li K; Talmud PJ; Sofat R; Stephens JW; Hamsten A; Sanders J; Montgomery H; Neil A; Humphries SE
Article: THE LANCET. 2012;379(9822):1205-1213
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Sarwar N; Butterworth AS; Freitag DF; Gregson J; Willeit P; Gorman DN; Gao P; Saleheen D; Rendon A; Nelson CP; Braund PS; Hall AS; Chasman DI; Tybjaerg-Hansen A; Chambers JC; Benjamin EJ; Franks PW; Clarke R; Wilde AAM; Trip MD; Steri M; Witteman JCM; Qi L; van der Schoot CE; de Faire U; Erdmann J; Stringham HM; Koenig W; Rader DJ; Melzer D; Reich D; Psaty BM; Kleber ME; Panagiotakos DB; Willeit J; Wennberg P; Woodward M; Adamovic S; Rimm EB; Meade TW; Gillum RF; Shaffer JA; Hofman A; Onat A; Sundstrom J; Wassertheil-Smoller S; Mellstrom D; Gallacher J; Cushman M; Tracy RP; Kauhanen J; Karlsson M; Salonen JT; Wilhelmsen L; Amouyel P; Cantin B; Best LG; Ben-Shlomo Y; Manson JE; Davey-Smith G; de Bakker PIW; O'Donnell CJ; Wilson JF; Wilson AG; Assimes TL; Jansson J-O; Ohlsson C; Tivesten A; Ljunggren O; Reilly MP; Hamsten A; Ingelsson E; Cambien F; Hung J; Thomas GN; Boehnke M; Schunkert H; Asselbergs FW; Kastelein JJP; Gudnason V; Salomaa V; Harris TB; Kooner JS; Allin KH; Nordestgaard BG; Hopewell JC; Goodall AH; Ridker PM; Holm H; Watkins H; Ouwehand WH; Samani NJ; Kaptoge S; Di Angelantonio E; Harari O; Danesh J
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;90(3):410-425
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci
Saxena R; Elbers CC; Guo Y; Peter I; Gaunt TR; Mega JL; Lanktree MB; Tare A; Almoguera Castillo B; Li YR; Johnson T; Bruinenberg M; Gilbert-Diamond D; Rajagopalan R; Voight BF; Balasubramanyam A; Barnard J; Bauer F; Baumert J; Bhangale T; Boehm BO; Braund PS; Burton PR; Chandrupatla HR; Clarke R; Cooper-DeHoff RM; Crook ED; Davey-Smith G; Day IN; de Boer A; de Groot MCH; Drenos F; Ferguson J; Fox CS; Furlong CE; Gibson Q; Gieger C; Gilhuijs-Pederson LA; Glessner JT; Goel A; Gong Y; Grant SFA; Grobbee DE; Hastie C; Humphries SE; Kim CE; Kivimaki M; Kleber M; Meisinger C; Kumari M; Langaee TY; Lawlor DA; Li M; Lobmeyer MT; Maitland-van der Zee A-H; Meijs MFL; Molony CM; Morrow DA; Murugesan G; Musani SK; Nelson CP; Newhouse SJ; O'Connell JR; Padmanabhan S; Palmen J; Patel SR; Pepine CJ; Pettinger M; Price TS; Rafelt S; Ranchalis J; Rasheed A; Rosenthal E; Ruczinski I; Shah S; Shen H; Silbernagel G; Smith EN; Spijkerman AWM; Stanton A; Steffes MW; Thorand B; Trip M; van der Harst P; van der A DL; van Iperen EPA; van Setten J; van Vliet-Ostaptchouk JV; Verweij N; Wolffenbuttel BHR; Young T; Zafarmand MH; Zmuda JM; Boehnke M; Altshuler D; McCarthy M; Kao WHL; Pankow JS; Cappola TP; Sever P; Poulter N; Caulfield M; Dominiczak A; Shields DC; Bhatt DL; Zhang L; Curtis SP; Danesh J; Casas JP; van der Schouw YT; Onland-Moret NC; Doevendans PA; Dorn GWII; Farrall M; FitzGerald GA; Hamsten A; Hegele R; Hingorani AD; Hofker MH; Huggins GS; Illig T; Jarvik GP; Johnson JA; Klungel OH; Knowler WC; Koenig W; Maerz W; Meigs JB; Melander O; Munroe PB; Mitchell BD; Bielinski SJ; Rader DJ; Reilly MP; Rich SS; Rotter JI; Saleheen D; Samani NJ; Schadt EE; Shuldiner AR; Silverstein R; Kottke-Marchant K; Talmud PJ; Watkins H; Asselbergs FW; de Bakker PIW; McCaffery J; Wijmenga C; Sabatine MS; Wilson JG; Reiner A; Bowden DW; Hakonarson H; Siscovick DS; Keating BJ
Article: PLOS ONE. 2012;7(2):e32306
Combined Chromatin and Expression Analysis Reveals Specific Regulatory Mechanisms within Cytokine Genes in the Macrophage Early Immune Response
Iglesias MJ; Reilly S-J; Emanuelsson O; Sennblad B; Najafabadi MP; Folkersen L; Malarstig A; Lagergren J; Eriksson P; Hamsten A; Odeberg J
Article: OBESITY. 2012;20(1):88-94
Obesity-Related Derangements of Coagulation and Fibrinolysis: A Study of Obesity-Discordant Monozygotic Twin Pairs
Kaye SM; Pietilainen KH; Kotronen A; Joutsi-Korhonen L; Kaprio J; Yki-Jarvinen H; Silveira A; Hamsten A; Lassila R; Rissanen A
Article: PLOS ONE. 2012;7(5):e37803
Involvement of SIK3 in Glucose and Lipid Homeostasis in Mice
Uebi T; Itoh Y; Hatano O; Kumagai A; Sanosaka M; Sasaki T; Sasagawa S; Doi J; Tatsumi K; Mitamura K; Morii E; Aozasa K; Kawamura T; Okumura M; Nakae J; Takikawa H; Fukusato T; Koura M; Nish M; Hamsten A; Silveira A; Bertorello AM; Kitagawa K; Nagaoka Y; Kawahara H; Tomonaga T; Naka T; Ikegawa S; Tsumaki N; Matsuda J; Takemori H
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2011;89(6):688-700
Blood Pressure Loci Identified with a Gene-Centric Array
Johnson T; Gaunt TR; Newhouse SJ; Padmanabhan S; Tomaszewski M; Kumari M; Morris RW; Tzoulaki I; O'Brien ET; Poulter NR; Sever P; Shields DC; Thom S; Wannamethee SG; Whincup PH; Brown MJ; Connell JM; Dobson RJ; Howard PJ; Mein CA; Onipinla A; Shaw-Hawkins S; Zhang Y; Smith GD; Day INM; Lawlor DA; Goodall AH; Fowkes FG; Abecasis GR; Elliott P; Gateva V; Braund PS; Burton PR; Nelson CP; Tobin MD; van der Harst P; Glorioso N; Neuvrith H; Salvi E; Staessen JA; Stucchi A; Devos N; Jeunemaitre X; Plouin P-F; Tichet J; Juhanson P; Org E; Putku M; Sober S; Veldre G; Viigimaa M; Levinsson A; Rosengren A; Thelle DS; Hastie CE; Hedner T; Lee WK; Melander O; Wahlstrand B; Hardy R; Wong A; Cooper JA; Palmen J; Chen L; Stewart AFR; Wells GA; Westra H-J; Wolfs MGM; Clarke R; Franzosi MG; Goel A; Hamsten A; Lathrop M; Peden JF; Seedorf U; Watkins H; Ouwehand WH; Sambrook J; Stephens J; Casas J-P; Drenos F; Holmes MV; Kivimaki M; Shah S; Shah T; Talmud PJ; Whittaker J; Wallace C; Delles C; Laan M; Kuh D; Humphries SE; Nyberg F; Cusi D; Roberts R; Newton-Cheh C; Franke L; Stanton AV; Dominiczak AF; Farrall M; Hingorani AD; Samani NJ; Caulfield MJ; Munroe PB
Article: JOURNAL OF HYPERTENSION. 2011;29(12):2395-2403
Salt-inducible kinase 1 influences Na⁺,K⁺-ATPase activity in vascular smooth muscle cells and associates with variations in blood pressure
Popov S; Silveira A; Wagsater D; Takemori H; Oguro R; Matsumoto S; Sugimoto K; Kamide K; Hirose T; Satoh M; Metoki H; Kikuya M; Ohkubo T; Katsuya T; Rakugi H; Imai Y; Sanchez F; Leosdottir M; Syvanen A-C; Hamsten A; Melander O; Bertorello AM
Article: DIABETES. 2011;60(10):2624-2634
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
Strawbridge RJ; Dupuis J; Prokopenko I; Barker A; Ahlqvist E; Rybin D; Petrie JR; Travers ME; Bouatia-Naji N; Dimas AS; Nica A; Wheeler E; Chen H; Voight BF; Taneera J; Kanoni S; Peden JF; Turrini F; Gustafsson S; Zabena C; Almgren P; Barker DJP; Barnes D; Dennison EM; Eriksson JG; Eriksson P; Eury E; Folkersen L; Fox CS; Frayling TM; Goel A; Gu HF; Horikoshi M; Isomaa B; Jackson AU; Jameson KA; Kajantie E; Kerr-Conte J; Kuulasmaa T; Kuusisto J; Loos RJF; Luan J; Makrilakis K; Manning AK; Teresa Martinez-Larrad M; Narisu N; Mannila MN; Ohrvik J; Osmond C; Pascoe L; Payne F; Sayer AA; Sennblad B; Silveira A; Stancakova A; Stirrups K; Swift AJ; Syvanen A-C; Tuomi T; van 't Hooft FM; Walker M; Weedon MN; Xie W; Zethelius B; Ongen H; Malarstig A; Hopewell JC; Saleheen D; Chambers J; Parish S; Danesh J; Kooner J; Ostenson C-G; Lind L; Cooper CC; Serrano-Rios M; Ferrannini E; Forsen TJ; Clarke R; Franzosi MG; Seedorf U; Watkins H; Froguel P; Johnson P; Deloukas P; Collins FS; Laakso M; Dermitzakis ET; Boehnke M; McCarthy MI; Wareham NJ; Groop L; Pattou F; Gloyn AL; Dedoussis GV; Lyssenko V; Meigs JB; Barroso I; Watanabe RM; Ingelsson E; Langenberg C; Hamsten A; Florez JC
Article: OBESITY. 2011;19(10):2031-2037
Variants at the Endocannabinoid Receptor CB1 Gene (CNR1) and Insulin Sensitivity, Type 2 Diabetes, and Coronary Heart Disease
de Miguel-Yanes JM; Manning AK; Shrader P; McAteer JB; Goel A; Hamsten A; Fox CS; Florez JC; Dupuis J; Meigs JB
Article: NATURE. 2011;478(7367):103-109
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
Ehret GB; Munroe PB; Rice KM; Bochud M; Johnson AD; Chasman DI; Smith AV; Tobin MD; Verwoert GC; Hwang S-J; Pihur V; Vollenweider P; O'Reilly PF; Amin N; Bragg-Gresham JL; Teumer A; Glazer NL; Launer L; Zhao JH; Aulchenko Y; Heath S; Sober S; Parsa A; Luan J; Arora P; Dehghan A; Zhang F; Lucas G; Hicks AA; Jackson AU; Peden JF; Tanaka T; Wild SH; Rudan I; Igl W; Milaneschi Y; Parker AN; Fava C; Chambers JC; Fox ER; Kumari M; Go MJ; van der Harst P; Kao WHL; Sjogren M; Vinay DG; Alexander M; Tabara Y; Shaw-Hawkins S; Whincup PH; Liu Y; Shi G; Kuusisto J; Tayo B; Seielstad M; Sim X; Khanh-Dung HN; Lehtimaki T; Matullo G; Wu Y; Gaunt TR; Onland-Moret NC; Cooper MN; Platou CGP; Org E; Hardy R; Dahgam S; Palmen J; Vitart V; Braund PS; Kuznetsova T; Uiterwaal CSPM; Adeyemo A; Palmas W; Campbell H; Ludwig B; Tomaszewski M; Tzoulaki I; Palmer ND; Aspelund T; Garcia M; Chang Y-PC; O'Connell JR; Steinle NI; Grobbee DE; Arking DE; Kardia SL; Morrison AC; Hernandez D; Najjar S; McArdle WL; Hadley D; Brown MJ; Connell JM; Hingorani AD; Day INM; Lawlor DA; Beilby JP; Lawrence RW; Clarke R; Hopewell JC; Ongen H; Dreisbach AW; Li Y; Young JH; Bis JC; Kahonen M; Viikari J; Adair LS; Lee NR; Chen M-H; Olden M; Pattaro C; Bolton JAH; Koettgen A; Bergmann S; Mooser V; Chaturvedi N; Frayling TM; Islam M; Jafar TH; Erdmann J; Kulkarni SR; Bornstein SR; Graessler J; Groop L; Voight BF; Kettunen J; Howard P; Taylor A; Guarrera S; Ricceri F; Emilsson V; Plump A; Barroso IS; Khaw K-T; Weder AB; Hunt SC; Sun YV; Bergman RN; Collins FS; Bonnycastle LL; Scott LJ; Stringham HM; Peltonen L; Perola M; Vartiainen E; Brand S-M; Staessen JA; Wang TJ; Burton PR; Artigas MS; Dong Y; Snieder H; Wang X; Zhu H; Lohman KK; Rudock ME; Heckbert SR; Smith NL; Wiggins KL; Doumatey A; Shriner D; Veldre G; Viigimaa M; Kinra S; Prabhakaran D; Tripathy V; Langefeld CD; Rosengren A; Thelle DS; Corsi AM; Singleton A; Forrester T; Hilton G; McKenzie CA; Salako T; Iwai N; Kita Y; Ogihara T; Ohkubo T; Okamura T; Ueshima H; Umemura S; Eyheramendy S; Meitinger T; Wichmann H-E; Cho YS; Kim H-L; Lee J-Y; Scott J; Sehmi JS; Zhang W; Hedblad B; Nilsson P; Smith GD; Wong A; Narisu N; Stancakova A; Raffel LJ; Yao J; Kathiresan S; O'Donnell CJ; Schwartz SM; Ikram MA; Longstreth WTJ; Mosley TH; Seshadri S; Shrine NRG; Wain LV; Morken MA; Swift AJ; Laitinen J; Prokopenko I; Zitting P; Cooper JA; Humphries SE; Danesh J; Rasheed A; Goel A; Hamsten A; Watkins H; Bakker SJL; van Gilst WH; Janipalli CS; Mani KR; Yajnik CS; Hofman A; Mattace-Raso FUS; Oostra BA; Demirkan A; Isaacs A; Rivadeneira F; Lakatta EG; Orru M; Scuteri A; Ala-Korpela M; Kangas AJ; Lyytikainen L-P; Soininen P; Tukiainen T; Wurtz P; Ong RT-H; Doerr M; Kroemer HK; Voelker U; Voelzke H; Galan P; Hercberg S; Lathrop M; Zelenika D; Deloukas P; Mangino M; Spector TD; Zhai G; Meschia JF; Nalls MA; Sharma P; Terzic J; Kumar MVK; Denniff M; Zukowska-Szczechowska E; Wagenknecht LE; Fowkes FGR; Charchar FJ; Schwarz PEH; Hayward C; Guo X; Rotimi C; Bots ML; Brand E; Samani NJ; Polasek O; Talmud PJ; Nyberg F; Kuh D; Laan M; Hveem K; Palmer LJ; van der Schouw YT; Casas JP; Mohlke KL; Vineis P; Raitakari O; Ganesh SK; Wong TY; Tai ES; Cooper RS; Laakso M; Rao DC; Harris TB; Morris RW; Dominiczak AF; Kivimaki M; Marmot MG; Miki T; Saleheen D; Chandak GR; Coresh J; Navis G; Salomaa V; Han B-G; Zhu X; Kooner JS; Melander O; Ridker PM; Bandinelli S; Gyllensten UB; Wright AF; Wilson JF; Ferrucci L; Farrall M; Tuomilehto J; Pramstaller PP; Elosua R; Soranzo N; Sijbrands EJG; Altshuler D; Loos RJF; Shuldiner AR; Gieger C; Meneton P; Uitterlinden AG; Wareham NJ; Gudnason V; Rotter JI; Rettig R; Uda M; Strachan DP; Witteman JCM; Hartikainen A-L; Beckmann JS; Boerwinkle E; Vasan RS; Boehnke M; Larson MG; Jarvelin M-R; Psaty BM; Abecasis GR; Chakravarti A; Elliott P; van Duijn CM; Newton-Cheh C; Levy D; Caulfield MJ; Johnson T
Article: NATURE GENETICS. 2011;43(10):1005-1011
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure
Wain LV; Verwoert GC; O'Reilly PF; Shi G; Johnson T; Johnson AD; Bochud M; Rice KM; Henneman P; Smith AV; Ehret GB; Amin N; Larson MG; Mooser V; Hadley D; Doerr M; Bis JC; Aspelund T; Esko T; Janssens ACJW; Zhao JH; Heath S; Laan M; Fu J; Pistis G; Luan J; Arora P; Lucas G; Pirastu N; Pichler I; Jackson AU; Webster RJ; Zhang F; Peden JF; Schmidt H; Tanaka T; Campbell H; Igl W; Milaneschi Y; Hottenga J-J; Vitart V; Chasman DI; Trompet S; Bragg-Gresham JL; Alizadeh BZ; Chambers JC; Guo X; Lehtimaki T; Kuehnel B; Lopez LM; Polasek O; Boban M; Nelson CP; Morrison AC; Pihur V; Ganesh SK; Hofman A; Kundu S; Mattace-Raso FUS; Rivadeneira F; Sijbrands EJG; Uitterlinden AG; Hwang S-J; Vasan RS; Wang TJ; Bergmann S; Vollenweider P; Waeber G; Laitinen J; Pouta A; Zitting P; McArdle WL; Kroemer HK; Voelker U; Voelzke H; Glazer NL; Taylor KD; Harris TB; Alavere H; Haller T; Keis A; Tammesoo M-L; Aulchenko Y; Barroso I; Khaw K-T; Galan P; Hercberg S; Lathrop M; Eyheramendy S; Org E; Sober S; Lu X; Nolte IM; Penninx BW; Corre T; Masciullo C; Sala C; Groop L; Voight BF; Melander O; O'Donnell CJ; Salomaa V; d'Adamo AP; Fabretto A; Faletra F; Ulivi S; Del Greco FM; Facheris M; Collins FS; Bergman RN; Beilby JP; Hung J; Musk AW; Mangino M; Shin S-Y; Soranzo N; Watkins H; Goel A; Hamsten A; Gider P; Loitfelder M; Zeginigg M; Hernandez D; Najjar SS; Navarro P; Wild SH; Corsi AM; Singleton A; de Geus EJC; Willemsen G; Parker AN; Rose LM; Buckley B; Stott D; Orru M; Uda M; van der Klauw MM; Zhang W; Li X; Scott J; Chen Y-DI; Burke GL; Kahonen M; Viikari J; Doering A; Meitinger T; Davies G; Starr JM; Emilsson V; Plump A; Lindeman JH; 't Hoen PAC; Koenig IR; Felix JF; Clarke R; Hopewell JC; Ongen H; Breteler M; Debette S; DeStefano AL; Fornage M; Mitchell GF; Smith NL; Holm H; Stefansson K; Thorleifsson G; Thorsteinsdottir U; Samani NJ; Preuss M; Rudan I; Hayward C; Deary IJ; Wichmann H-E; Raitakari OT; Palmas W; Kooner JS; Stolk RP; Jukema JW; Wright AF; Boomsma DI; Bandinelli S; Gyllensten UB; Wilson JF; Ferrucci L; Schmidt R; Farrall M; Spector TD; Palmer LJ; Tuomilehto J; Pfeufer A; Gasparini P; Siscovick D; Altshuler D; Loos RJF; Toniolo D; Snieder H; Gieger C; Meneton P; Wareham NJ; Oostra BA; Metspalu A; Launer L; Rettig R; Strachan DP; Beckmann JS; Witteman JCM; Erdmann J; van Dijk KW; Boerwinkle E; Boehnke M; Ridker PM; Jarvelin M-R; Chakravarti A; Abecasis GR; Gudnason V; Newton-Cheh C; Levy D; Munroe PB; Psaty BM; Caulfield MJ; Rao DC; Tobin MD; Elliott P; van Duijn CM
Article: JOURNAL OF INTERNAL MEDICINE. 2011;270(3):229-236
Plasma CD93 concentration is a potential novel biomarker for coronary artery disease
Malarstig A; Silveira A; Wagsater D; Ohrvik J; Backlund A; Samnegard A; Khademi M; Hellenius M-L; Leander K; Olsson T; Uhlen M; de Faire U; Eriksson P; Hamsten A
Article: PLOS GENETICS. 2011;7(9):e1002260
Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease
Butterworth AS; Braund PS; Farrall M; Hardwick RJ; Saleheen D; Peden JF; Soranzo N; Chambers JC; Sivapalaratnam S; Kleber ME; Keating B; Qasim A; Klopp N; Erdmann J; Assimes TL; Ball SG; Balmforth AJ; Barnes TA; Basart H; Baumert J; Bezzina CR; Boerwinkle E; Boehm BO; Brocheton J; Bugert P; Cambien F; Clarke R; Codd V; Collins R; Couper D; Cupples LA; de Jong JS; Diemert P; Ejebe K; Elbers CC; Elliott P; Fornage M; Franzosi M-G; Frossard P; Garner S; Goel A; Goodall AH; Hengstenberg C; Hunt SE; Kastelein JJP; Klungel OH; Klueter H; Koch K; Koenig IR; Kooner AS; Laaksonen R; Lathrop M; Li M; Liu K; McPherson R; Musameh MD; Musani S; Nelson CP; O'Donnell CJ; Ongen H; Papanicolaou G; Peters A; Peters BJM; Potter S; Psaty BM; Qu L; Rader DJ; Rasheed A; Rice C; Scott J; Seedorf U; Sehmi JS; Sotoodehnia N; Stark K; Stephens J; van der Schoot CE; van der Schouw YT; Thorsteinsdottir U; Tomaszewski M; van der Harst P; Vasan RS; Wilde AAM; Willenborg C; Winkelmann BR; Zaidi M; Zhang W; Ziegler A; de Bakker PIW; Koenig W; Maerz W; Trip MD; Reilly MP; Kathiresan S; Schunkert H; Hamsten A; Hall AS; Kooner JS; Thompson SG; Thompson JR; Deloukas P; Ouwehand WH; Watkins H; Danesh J; Samani NJ
Article: NATURE. 2011;476(7359):214-219
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Sawcer S; Hellenthal G; Pirinen M; Spencer CCA; Patsopoulos NA; Moutsianas L; Dilthey A; Su Z; Freeman C; Hunt SE; Edkins S; Gray E; Booth DR; Potter SC; Goris A; Band G; Oturai AB; Strange A; Saarela J; Bellenguez C; Fontaine B; Gillman M; Hemmer B; Gwilliam R; Zipp F; Jayakumar A; Martin R; Leslie S; Hawkins S; Giannoulatou E; D'alfonso S; Blackburn H; Boneschi FM; Liddle J; Harbo HF; Perez ML; Spurkland A; Waller MJ; Mycko MP; Ricketts M; Comabella M; Hammond N; Kockum I; McCann OT; Ban M; Whittaker P; Kemppinen A; Weston P; Hawkins C; Widaa S; Zajicek J; Dronov S; Robertson N; Bumpstead SJ; Barcellos LF; Ravindrarajah R; Abraham R; Alfredsson L; Ardlie K; Aubin C; Baker A; Baker K; Baranzini SE; Bergamaschi L; Bergamaschi R; Bernstein A; Berthele A; Boggild M; Bradfield JP; Brassat D; Broadley SA; Buck D; Butzkueven H; Capra R; Carroll WM; Cavalla P; Celius EG; Cepok S; Chiavacci R; Clerget-Darpoux F; Clysters K; Comi G; Cossburn M; Cournu-Rebeix I; Cox MB; Cozen W; Cree BAC; Cross AH; Cusi D; Daly MJ; Davis E; de Bakker PIW; Debouverie M; D'hooghe MB; Dixon K; Dobosi R; Dubois B; Ellinghaus D; Elovaara I; Esposito F; Fontenille C; Foote S; Franke A; Galimberti D; Ghezzi A; Glessner J; Gomez R; Gout O; Graham C; Grant SFA; Guerini FR; Hakonarson H; Hall P; Hamsten A; Hartung H-P; Heard RN; Heath S; Hobart J; Hoshi M; Infante-Duarte C; Ingram G; Ingram W; Islam T; Jagodic M; Kabesch M; Kermode AG; Kilpatrick TJ; Kim C; Klopp N; Koivisto K; Larsson M; Lathrop M; Lechner-Scott JS; Leone MA; Leppa V; Liljedahl U; Bomfim IL; Lincoln RR; Link J; Liu J; Lorentzen AR; Lupoli S; Macciardi F; Mack T; Marriott M; Martinelli V; Mason D; McCauley JL; Mentch F; Mero I-L; Mihalova T; Montalban X; Mottershead J; Myhr K-M; Naldi P; Ollier W; Page A; Palotie A; Pelletier J; Piccio L; Pickersgill T; Piehl F; Pobywajlo S; Quach HL; Ramsay PP; Reunanen M; Reynolds R; Rioux J; Rodegher M; Roesner S; Rubio JP; Rueckert I-M; Salvetti M; Salvi E; Santaniello A; Schaefer CA; Schreiber S; Schulze C; Scott RJ; Sellebjerg F; Selmaj KW; Sexton D; Shen L; Simms-Acuna B; Skidmore S; Sleiman PMA; Smestad C; Sorensen PS; Sondergaard HB; Stankovich J; Strange RC; Sulonen A-M; Sundqvist E; Syvaenen A-C; Taddeo F; Taylor B; Blackwell JM; Tienari P; Bramon E; Tourbah A; Brown MA; Tronczynska E; Casas JP; Tubridy N; Corvin A; Vickery J; Jankowski J; Villoslada P; Markus HS; Wang K; Mathew CG; Wason J; Palmer CNA; Wichmann H-E; Plomin R; Willoughby E; Rautanen A; Winkelmann J; Wittig M; Trembath RC; Yaouanq J; Viswanathan AC; Zhang H; Wood NW; Zuvich R; Deloukas P; Langford C; Duncanson A; Oksenberg JR; Pericak-Vance MA; Haines JL; Olsson T; Hillert J; Ivinson AJ; De Jager PL; Peltonen L; Stewart GJ; Hafler DA; Hauser SL; McVean G; Donnelly P; Compston A
Article: JOURNAL OF LIPID RESEARCH. 2011;52(8):1569-1574
Plasma lecithin: cholesterol acyltransferase and carotid intima-media thickness in European individuals at high cardiovascular risk
Calabresi L; Baldassarre D; Simonelli S; Gomaraschi M; Amato M; Castelnuovo S; Frigerio B; Ravani A; Sansaro D; Kauhanen J; Rauramaa R; de Faire U; Hamsten A; Smit AJ; Mannarino E; Humphries SE; Giral P; Veglia F; Sirtori CR; Franceschini G; Tremoli E
Article: BMC MEDICAL GENOMICS. 2011;4:51
Genome wide association study identifies KCNMA1 contributing to human obesity
Jiao H; Arner P; Hoffstedt J; Brodin D; Dubern B; Czernichow S; van't Hooft F; Axelsson T; Pedersen O; Hansen T; Sorensen TIA; Hebebrand J; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2011;96(6):E962-E966
Genetic Association and Gene Expression Analysis Identify FGFR1 as a New Susceptibility Gene for Human Obesity
Jiao H; Arner P; Dickson SL; Vidal H; Mejhert N; Henegar C; Taube M; Hansson C; Hinney A; Galan P; Simon C; Silveira A; Benrick A; Jansson J-O; Bouloumie A; Langin D; Laville M; Debard C; Axelsson T; Ryden M; Kere J; Dahlman-Wright K; Hamsten A; Clement K; Dahlman I
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2011;19(4):479-484
A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE
Sandling JK; Garnier S; Sigurdsson S; Wang C; Nordmark G; Gunnarsson I; Svenungsson E; Padyukov L; Sturfelt G; Jonsen A; Bengtsson AA; Truedsson L; Eriksson C; Rantapaa-Dahlqvist S; Malarstig A; Strawbridge RJ; Hamsten A; Criswell LA; Graham RR; Behrens TW; Eloranta M-L; Alm G; Ronnblom L; Syvanen A-C
Article: PLOS ONE. 2011;6(3):e17652
A Common Polymorphism in the Promoter Region of the TNFSF4 Gene Is Associated with Lower Allele-Specific Expression and Risk of Myocardial Infarction
Ria M; Lagercrantz J; Samnegard A; Boquist S; Hamsten A; Eriksson P
Article: NATURE GENETICS. 2011;43(4):339-U89
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
Peden JF; Hopewell JC; Saleheen D; Chambers JC; Hager J; Soranzo N; Collins R; Danesh J; Elliott P; Farrall M; Stirrups K; Zhang W; Hamsten A; Parish S; Lathrop M; Watkins H; Clarke R; Deloukas P; Kooner JS; Goel A; Ongen H; Strawbridge RJ; Heath S; Malarstig A; Helgadottir A; Ohrvik J; Murtaza M; Potter S; Hunt SE; Delepine M; Jalilzadeh S; Axelsson T; Syvanen A-C; Gwilliam R; Bumpstead S; Gray E; Edkins S; Folkersen L; Kyriakou T; Franco-Cereceda A; Gabrielsen A; Seedorf U; Eriksson P; Offer A; Bowman L; Sleight P; Armitage J; Peto R; Abecasis G; Ahmed N; Caulfield M; Donnelly P; Froguel P; Kooner AS; McCarthy MI; Samani NJ; Scott J; Sehmi J; Silveira A; Hellenius M-L; van't Hooft FM; Olsson G; Rust S; Assmann G; Barlera S; Tognoni G; Franzosi MG; Linksted P; Green FR; Rasheed A; Zaidi M; Shah N; Samuel M; Mallick NH; Azhar M; Zaman KS; Samad A; Ishaq M; Gardezi AR; Memon F-U; Frossard PM; Spector T; Peltonen L; Nieminen MS; Sinisalo J; Salomaa V; Ripatti S; Bennett D; Leander K; Gigante B; de Faire U; Pietri S; Gori F; Marchioli R; Sivapalaratnam S; Kastelein JJP; Trip MD; Theodoraki EV; Dedoussis GV; Engert JC; Yusuf S; Anand SS
Article: JOURNAL OF DIABETES AND ITS COMPLICATIONS. 2011;25(2):97-106
The prevalence of peripheral neuropathy in a population-based study of patients with type 2 diabetes in Sweden
Karvestedt L; Martensson E; Grill V; Elofsson S; von Wendt G; Hamsten A; Brismar K
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2011;31(3):691-697
Impaired Splicing of Fibronectin Is Associated With Thoracic Aortic Aneurysm Formation in Patients With Bicuspid Aortic Valve
Paloschi V; Kurtovic S; Folkersen L; Gomez D; Wagsaeter D; Roy J; Petrini J; Eriksson MJ; Caidahl K; Hamsten A; Liska J; Michel J-B; Franco-Cereceda A; Eriksson P
Article: JOURNAL OF INTERFERON AND CYTOKINE RESEARCH. 2011;31(2):259-264
Genetic and Environmental Influences on the Plasma Interleukin-6 Concentration in Patients with a Recent Myocardial Infarction: A Case-Control Study
Bennermo M; Nordin M; Lundman P; Boqvist S; Held C; Samnegard A; Ericsson C-G; Silveira A; Hamsten A; Nastase MM; Tornvall P
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 2011;88(1):6-18
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height
Lanktree MB; Guo Y; Murtaza M; Glessner JT; Bailey SD; Onland-Moret NC; Lettre G; Ongen H; Rajagopalan R; Johnson T; Shen H; Nelson CP; Klopp N; Baumert J; Padmanabhan S; Pankratz N; Pankow JS; Shah S; Taylor K; Barnard J; Peters BJ; Maloney CM; Lobmeyer MT; Stanton A; Zafarmand MH; Romaine SPR; Mehta A; van Iperen EPA; Gong Y; Price TS; Smith EN; Kim CE; Li YR; Asselbergs FW; Atwood LD; Bailey KM; Bhatt D; Bauer F; Behr ER; Bhangale T; Boer JMA; Boehm BO; Bradfield JP; Brown M; Braund PS; Burton PR; Carty C; Chandrupatla HR; Chen W; Connell J; Dalgeorgou C; de Boer A; Drenos F; Elbers CC; Fang JC; Fox CS; Frackelton EC; Fuchs B; Furlong CE; Gibson Q; Gieger C; Goe A; Grobbee DE; Hastie C; Howard PJ; Huang G-H; Johnson WC; Li Q; Kleber ME; Klein BEK; Klein R; Kooperberg C; Ky B; LaCroix A; Lanken P; Lathrop M; Li M; Marshal V; Melander O; Mentch FD; Meyer NJ; Monda KL; Montpetit A; Murugesan G; Nakayama K; Nondah D; Onipinla A; Rafelt S; Newhouse SJ; Otieno FG; Patel SR; Putt ME; Rodriguez S; Safa RN; Sawyer DB; Schreiner PJ; Simpson C; Sivapalaratnam S; Srinivasan SR; Suver C; Swergold G; Sweitzer NK; Thomas KA; Thorand B; Timpson NJ; Tischfield S; Tobin M; Tomaszweski M; Verschuren WMM; Wallace C; Winkelmann B; Zhang H; Zheng D; Zhang L; Zmuda JM; Clarke R; Balmforth AJ; Danesh J; Day IN; Schork NJ; de Bakker PIW; Delles C; Duggan D; Hingorani AD; Hirschhorn JN; Hofker MH; Humphries SE; Kivimaki M; Lawlor DA; Kottke-Marchant K; Mega JL; Mitchell BD; Morrow DA; Palmen J; Redline S; Shields DC; Shuldiner AR; Sleiman PM; Smith GD; Farrall M; Jamshidi Y; Christiani DC; Casas JP; Hall AS; Doevendans PA; Christie JD; Berenson GS; Murray SS; Illig T; Dorn GWII; Cappola TP; Boerwinkle E; Sever P; Rader DJ; Reilly MP; Caulfield M; Talmud PJ; Topol E; Engert JC; Wang K; Dominiczak A; Hamsten A; Curtis SP; Silverstein RL; Lange LA; Sabatine MS; Trip M; Saleheen D; Peden JF; Cruickshanks KJ; Maerz W; O'Connell JR; Klungel OH; Wijmenga C; Maitland-van der Zee AH; Schadt EE; Johnson JA; Jarvik GP; Papanicolaou GJ; Watkins H; Grant SFA; Munroe PB; North KE; Samani NJ; Koenig W; Gaunt TR; Anand SS; van der Schouw YT; Kumari M; Soranzo N; FitzGerald GA; Reiner A; Hegele RA; Hakonarson H; Keating BJ
Article: MOLECULAR MEDICINE. 2011;17(11-12):1365-1373
Unraveling Divergent Gene Expression Profiles in Bicuspid and Tricuspid Aortic Valve Patients with Thoracic Aortic Dilatation: The ASAP Study
Folkersen L; Wagsater D; Paloschi V; Jackson V; Petrini J; Kurtovic S; Maleki S; Eriksson MJ; Caidahl K; Hamsten A; Michel J-B; Liska J; Gabrielsen A; Franco-Cereceda A; Eriksson P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(49):21093-21097
Increased expression of leukotriene C₄ synthase and predominant formation of cysteinyl-leukotrienes in human abdominal aortic aneurysm
Di Gennaro A; Wagsater D; Mayranpaa MI; Gabrielsen A; Swedenborg J; Hamsten A; Samuelsson B; Eriksson P; Haeggstrom JZ
Article: DIABETES CARE. 2010;33(11):2451-2456
Mannose-Binding Lectin Genotype and Phenotype in Patients With Type 2 Diabetes and Myocardial Infarction
Mellbin LG; Hamsten A; Malmberg K; Steffensen R; Ryden L; Ohrvik J; Hansen TK
Article: NATURE GENETICS. 2010;42(11):949-U160
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Heid IM; Jackson AU; Randall JC; Winkler TW; Qi L; Steinthorsdottir V; Thorleifsson G; Zillikens MC; Speliotes EK; Maegi R; Workalemahu T; White CC; Bouatia-Naji N; Harris TB; Berndt SI; Ingelsson E; Willer CJ; Weedon MN; Luan J; Vedantam S; Esko T; Kilpelaeinen TO; Kutalik Z; Li S; Monda KL; Dixon AL; Holmes CC; Kaplan LM; Liang L; Min JL; Moffatt MF; Molony C; Nicholson G; Schadt EE; Zondervan KT; Feitosa MF; Ferreira T; Allen HL; Weyant RJ; Wheeler E; Wood AR; Estrada K; Goddard ME; Lettre G; Mangino M; Nyholt DR; Purcell S; Smith AV; Visscher PM; Yang J; McCarroll SA; Nemesh J; Voight BF; Absher D; Amin N; Aspelund T; Coin L; Glazer NL; Hayward C; Heard-Costa NL; Hottenga J-J; Johansson A; Johnson T; Kaakinen M; Kapur K; Ketkar S; Knowles JW; Kraft P; Kraja AT; Lamina C; Leitzmann MF; McKnight B; Morris AP; Ong KK; Perry JRB; Peters MJ; Polasek O; Prokopenko I; Rayner NW; Ripatti S; Rivadeneira F; Robertson NR; Sanna S; Sovio U; Surakka I; Teumer A; van Wingerden S; Vitart V; Zhao JH; Cavalcanti-Proenca C; Chines PS; Fisher E; Kulzer JR; Lecoeur C; Narisu N; Sandholt C; Scott LJ; Silander K; Stark K; Tammesoo M-L; Teslovich TM; Timpson NJ; Watanabe RM; Welch R; Chasman DI; Cooper MN; Jansson J-O; Kettunen J; Lawrence RW; Pellikka N; Perola M; Vandenput L; Alavere H; Almgren P; Atwood LD; Bennett AJ; Biffar R; Bonnycastle LL; Bornstein SR; Buchanan TA; Campbell H; Day INM; Dei M; Doerr M; Elliott P; Erdos MR; Eriksson JG; Freimer NB; Fu M; Gaget S; Geus EJC; Gjesing AP; Grallert H; Graessler J; Groves CJ; Guiducci C; Hartikainen A-L; Hassanali N; Havulinna AS; Herzig K-H; Hicks AA; Hui J; Igl W; Jousilahti P; Jula A; Kajantie E; Kinnunen L; Kolcic I; Koskinen S; Kovacs P; Kroemer HK; Krzelj V; Kuusisto J; Kvaloy K; Laitinen J; Lantieri O; Lathrop GM; Lokki M-L; Luben RN; Ludwig B; McArdle WL; McCarthy A; Morken MA; Nelis M; Neville MJ; Pare G; Parker AN; Peden JF; Pichler I; Pietilainen KH; Platou CGP; Pouta A; Ridderstrale M; Samani NJ; Saramies J; Sinisalo J; Smit JH; Strawbridge RJ; Stringham HM; Swift AJ; Teder-Laving M; Thomson B; Usala G; van Meurs JBJ; van Ommen G-J; Vatin V; Volpato CB; Wallaschofski H; Walters GB; Widen E; Wild SH; Willemsen G; Witte DR; Zgaga L; Zitting P; Beilby JP; James AL; Kahonen M; Lehtimaki T; Nieminen MS; Ohlsson C; Palmer LJ; Raitakari O; Ridker PM; Stumvoll M; Toenjes A; Viikari J; Balkau B; Ben-Shlomo Y; Bergman RN; Boeing H; Smith GD; Ebrahim S; Froguel P; Hansen T; Hengstenberg C; Hveem K; Isomaa B; Jorgensen T; Karpe F; Khaw K-T; Laakso M; Lawlor DA; Marre M; Meitinger T; Metspalu A; Midthjell K; Pedersen O; Salomaa V; Schwarz PEH; Tuomi T; Tuomilehto J; Valle TT; Wareham NJ; Arnold AM; Beckmann JS; Bergmann S; Boerwinkle E; Boomsma DI; Caulfield MJ; Collins FS; Eiriksdottir G; Gudnason V; Gyllensten U; Hamsten A; Hattersley AT; Hofman A; Hu FB; Illig T; Iribarren C; Jarvelin M-R; Kao WHL; Kaprio J; Launer LJ; Munroe PB; Oostra B; Penninx BW; Pramstaller PP; Psaty BM; Quertermous T; Rissanen A; Rudan I; Shuldiner AR; Soranzo N; Spector TD; Syvanen A-C; Uda M; Uitterlinden A; Voelzke H; Vollenweider P; Wilson JF; Witteman JC; Wright AF; Abecasis GR; Boehnke M; Borecki IB; Deloukas P; Frayling TM; Groop LC; Haritunians T; Hunter DJ; Kaplan RC; North KE; O'Connell JR; Peltonen L; Schlessinger D; Strachan DP; Hirschhorn JN; Assimes TL; Wichmann H-E; Thorsteinsdottir U; van Duijn CM; Stefansson K; Cupples LA; Loos RJF; Barroso I; McCarthy MI; Fox CS; Mohlke KL; Lindgren CM
Article: NATURE. 2010;467(7317):832-838
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Allen HL; Estrada K; Lettre G; Berndt SI; Weedon MN; Rivadeneira F; Willer CJ; Jackson AU; Vedantam S; Raychaudhuri S; Ferreira T; Wood AR; Weyant RJ; Segre AV; Speliotes EK; Wheeler E; Soranzo N; Park J-H; Yang J; Gudbjartsson D; Heard-Costa NL; Randall JC; Qi L; Smith AV; Maegi R; Pastinen T; Liang L; Heid IM; Luan J; Thorleifsson G; Winkler TW; Goddard ME; Lo KS; Palmer C; Workalemahu T; Aulchenko YS; Johansson A; Zillikens MC; Feitosa MF; Esko T; Johnson T; Ketkar S; Kraft P; Mangino M; Prokopenko I; Absher D; Albrecht E; Ernst F; Glazer NL; Hayward C; Hottenga J-J; Jacobs KB; Knowles JW; Kutalik Z; Monda KL; Polasek O; Preuss M; Rayner NW; Robertson NR; Steinthorsdottir V; Tyrer JP; Voight BF; Wiklund F; Xu J; Zhao JH; Nyholt DR; Pellikka N; Perola M; Perry JRB; Surakka I; Tammesoo M-L; Altmaier EL; Amin N; Aspelund T; Bhangale T; Boucher G; Chasman DI; Chen C; Coin L; Cooper MN; Dixon AL; Gibson Q; Grundberg E; Hao K; Junttila MJ; Kaplan LM; Kettunen J; Koenig IR; Kwan T; Lawrence RW; Levinson DF; Lorentzon M; McKnight B; Morris AP; Mueller M; Ngwa JS; Purcell S; Rafelt S; Salem RM; Salvi E; Sanna S; Shi J; Sovio U; Thompson JR; Turchin MC; Vandenput L; Verlaan DJ; Vitart V; White CC; Ziegler A; Almgren P; Balmforth AJ; Campbell H; Citterio L; De Grandi A; Dominiczak A; Duan J; Elliott P; Elosua R; Eriksson JG; Freimer NB; Geus EJC; Glorioso N; Haiqing S; Hartikainen A-L; Havulinna AS; Hicks AA; Hui J; Igl W; Illig T; Jula A; Kajantie E; Kilpelaeinen TO; Koiranen M; Kolcic I; Koskinen S; Kovacs P; Laitinen J; Liu J; Lokki M-L; Marusic A; Maschio A; Meitinger T; Mulas A; Pare G; Parker AN; Peden JF; Petersmann A; Pichler I; Pietilainen KH; Pouta A; Riddertrale M; Rotter JI; Sambrook JG; Sanders AR; Schmidt CO; Sinisalo J; Smit JH; Stringham HM; Walters GB; Widen E; Wild SH; Willemsen G; Zagato L; Zgaga L; Zitting P; Alavere H; Farrall M; McArdle WL; Nelis M; Peters MJ; Ripatti S; vVan Meurs JBJ; Aben KK; Ardlie KG; Beckmann JS; Beilby JP; Bergman RN; Bergmann S; Collins FS; Cusi D; den Heijer M; Eiriksdottir G; Gejman PV; Hall AS; Hamsten A; Huikuri HV; Iribarren C; Kahonen M; Kaprio J; Kathiresan S; Kiemeney L; Kocher T; Launer LJ; Lehtimaki T; Melander O; Mosley THJ; Musk AW; Nieminen MS; O'Donnell CJ; Ohlsson C; Oostra B; Palmer LJ; Raitakari O; Ridker PM; Rioux JD; Rissanen A; Rivolta C; Schunkert H; Shuldiner AR; Siscovick DS; Stumvoll M; Toenjes A; Tuomilehto J; van Ommen G-J; Viikari J; Heath AC; Martin NG; Montgomery GW; Province MA; Kayser M; Arnold AM; Atwood LD; Boerwinkle E; Chanock SJ; Deloukas P; Gieger C; Gronberg H; Hall P; Hattersley AT; Hengstenberg C; Hoffman W; Lathrop GM; Salomaa V; Schreiber S; Uda M; Waterworth D; Wright AF; Assimes TL; Barroso I; Hofman A; Mohlke KL; Boomsma DI; Caulfield MJ; Cupples LA; Erdmann J; Fox CS; Gudnason V; Gyllensten U; Harris TB; Hayes RB; Jarvelin M-R; Mooser V; Munroe PB; Ouwehand WH; Penninx BW; Pramstaller PP; Quertermous T; Rudan I; Samani NJ; Spector TD; Voelzke H; Watkins H; Wilson JF; Groop LC; Haritunians T; Hu FB; Kaplan RC; Metspalu A; North KE; Schlessinger D; Wareham NJ; Hunter DJ; O'Connell JR; Strachan DP; Schadt H-E; Thorsteinsdottir U; Peltonen L; Uitterlinden AG; Visscher PM; Chatterjee N; Loos RJF; Boehnke M; McCarthy MI; Ingelsson E; Lindgren CM; Abecasis GR; Stefansson K; Frayling TM; Hirschhorn JN
Article: JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY. 2010;23(9):985-992
The Feasibility of Velocity Vector Imaging by Transesophageal Echocardiography for Assessment of Elastic Properties of the Descending Aorta in Aortic Valve Disease
Petrini J; Yousry M; Rickenlund A; Liska J; Hamsten A; Eriksson P; Franco-Cereceda A; Caidahl K; Eriksson MJ
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 2010;59(9):1316-1318
Preliminary report: Zn-alpha2-glycoprotein genotype and serum levels are associated with serum lipids
Olofsson LE; Olsson B; Lystig T; Jacobson P; Jernas M; Sjoholm K; Gummesson A; Sjostrom L; Eriksson P; Hamsten A; Hale LP; Thelle DS; Carlsson B; Carlsson LMS
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2010;3(4):365-373
Association of Genetic Risk Variants With Expression of Proximal Genes Identifies Novel Susceptibility Genes for Cardiovascular Disease
Folkersen L; van't Hooft F; Chernogubova E; Agardh HE; Hansson GK; Hedin U; Liska J; Syvanen A-C; Paulssson-Berne G; Franco-Cereceda A; Hamsten A; Gabrielsen A; Eriksson P
Article: JOURNAL OF MOLECULAR MEDICINE. 2010;88(8):785-794
Telomeres are shorter in myocardial infarction patients compared to healthy subjects: correlation with environmental risk factors
Maubaret CG; Salpea KD; Jain A; Cooper JA; Hamsten A; Sanders J; Montgomery H; Neil A; Nair D; Humphries SE
Article: CURRENT ATHEROSCLEROSIS REPORTS. 2010;12(3):159-166
Genetics of Atherothrombosis and Thrombophilia
Malarstig A; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2010;30(5):962-967
DGAT1 Participates in the Effect of HNF4A on Hepatic Secretion of Triglyceride-Rich Lipoproteins
Krapivner S; Iglesias MJ; Silveira A; Tegner J; Bjorkegren J; Hamsten A; van't Hooft FM
Article: CIRCULATION. 2010;121(12):1382-1U45
Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium
Smith NL; Chen M-H; Dehghan A; Strachan DP; Basu S; Soranzo N; Hayward C; Rudan I; Sabater-Lleal M; Bis JC; de Maat MPM; Rumley A; Kong X; Yang Q; Williams FMK; Vitart V; Campbell H; Maelarstig A; Wiggins KL; Van Duijn CM; McArdle WL; Pankow JS; Johnson AD; Silveira A; McKnight B; Uitterlinden AG; Aleksic N; Meigs JB; Peters A; Koenig W; Cushman M; Kathiresan S; Rotter JI; Bovill EG; Hofman A; Boerwinkle E; Tofler GH; Peden JF; Psaty BM; Leebeek F; Folsom AR; Larson MG; Spector TD; Wright AF; Wilson JF; Hamsten A; Lumley T; Witteman JCM; Tang W; O'Donnell CJ
Article: EUROPEAN HEART JOURNAL. 2010;30(6):710-717
Concentration of apolipoprotein B is comparable with the apolipoprotein B/apolipoprotein A-I ratio and better than routine clinical lipid measurements in predicting coronary heart disease mortality: findings from a multi-ethnic US population
Sierra-Johnson J; Fisher RM; Romero-Corral A; Somers VK; Lopez-Jimenez F; Ohrvik J; Walldius G; Hellenius M-L; Hamsten A
Article: EUROPEAN HEART JOURNAL. 2010;31(5):614-622
Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study
Baldassarre D; Nyyssonen K; Rauramaa R; de Faire U; Hamsten A; Smit AJ; Mannarino E; Humphries SE; Giral P; Grossi E; Veglia F; Paoletti R; Tremoli E
Article: JOURNAL OF LIPID RESEARCH. 2010;51(1):103-111
Allele-specific regulation of MTTP expression influences the risk of ischemic heart disease
Aminoff A; Ledmyr H; Thulin P; Lundell K; Nunez L; Strandhagen E; Murphy C; Lidberg U; Westerbacka J; Franco-Cereceda A; Liska J; Nielsen LB; Gafvels M; Mannila MN; Hamsten A; Yki-Jarvinen H; Thelle D; Eriksson P; Boren J; Ehrenborg E
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2009;361(26):2518-2528
Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease
Clarke R; Peden JF; Hopewell JC; Kyriakou T; Goel A; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; de Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M
Article: PLOS GENETICS. 2009;5(12):e1000754
Multi-Organ Expression Profiling Uncovers a Gene Module in Coronary Artery Disease Involving Transendothelial Migration of Leukocytes and LIM Domain Binding 2: The Stockholm Atherosclerosis Gene Expression (STAGE) Study
Hagg S; Skogsberg J; Lundstrom J; Noori P; Nilsson R; Zhong H; Maleki S; Shang M-M; Brinne B; Bradshaw M; Bajic VB; Samnegard A; Silveira A; Kaplan LM; Gigante B; Leander K; de Faire U; Rosfors S; Lockowandt U; Liska J; Konrad P; Takolander R; Franco-Cereceda A; Schadt EE; Ivert T; Hamsten A; Tegner J; Bjorkegren J
Article: PLOS ONE. 2009;4(11):e7677
Relationship between CAD Risk Genotype in the Chromosome 9p21 Locus and Gene Expression. Identification of Eight New ANRIL Splice Variants
Folkersen L; Kyriakou T; Goel A; Peden J; Malarstig A; Paulsson-Berne G; Hamsten A; Franco-Cereceda A; Gabrielsen A; Eriksson P; Watkins H
Article: PLOS GENETICS. 2009;5(11):e1000730
Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis
Chasman DI; Pare G; Mora S; Hopewell JC; Peloso G; Clarke R; Cupples LA; Hamsten A; Kathiresan S; Maelarstig A; Ordovas JM; Ripatti S; Parker AN; Miletich JP; Ridker PM
Article: BLOOD. 2009;114(7):1417-1422
Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study
Malarstig A; Buil A; Carolos Souto J; Clarke R; Blanco-Vaca F; Fontcuberta J; Peden J; Andersen M; Silveira A; Barlera S; Seedorf U; Watkins H; Almasy L; Hamsten A; Manuel Soria J
Article: JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (JAMA). 2009;302(1):37-48
Genetic Loci Associated With C-Reactive Protein Levels and Risk of Coronary Heart Disease
Elliott P; Chambers JC; Zhang W; Clarke R; Hopewell JC; Peden JF; Erdmann J; Braund P; Engert JC; Bennett D; Coin L; Ashby D; Tzoulaki I; Brown IJ; Mt-Isa S; McCarthy MI; Peltonen L; Freimer NB; Farrall M; Ruokonen A; Hamsten A; Lim N; Froguel P; Waterworth DM; Vollenweider P; Waeber G; Jarvelin M-R; Mooser V; Scott J; Hall AS; Schunkert H; Anand SS; Collins R; Samani NJ; Watkins H; Kooner JS
Article: DIABETOLOGIA. 2009;52(6):1056-1060
A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans
Kotronen A; Johansson LE; Johansson LM; Roos C; Westerbacka J; Hamsten A; Bergholm R; Arkkila P; Arola J; Kiviluoto T; Fisher RM; Ehrenborg E; Orho-Melander M; Ridderstrale M; Groop L; Yki-Jarvinen H
Article: PLOS GENETICS. 2009;5(6):e1000508
Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
Lindgren CM; Heid IM; Randall JC; Lamina C; Steinthorsdottir V; Qi L; Speliotes EK; Thorleifsson G; Willer CJ; Herrera BM; Jackson AU; Lim N; Scheet P; Soranzo N; Amin N; Aulchenko YS; Chambers JC; Drong A; Luan J; Lyon HN; Rivadeneira F; Sanna S; Timpson NJ; Zillikens MC; Zhao JH; Almgren P; Bandinelli S; Bennett AJ; Bergman RN; Bonnycastle LL; Bumpstead SJ; Chanock SJ; Cherkas L; Chines P; Coin L; Cooper C; Crawford G; Doering A; Dominiczak A; Doney ASF; Ebrahim S; Elliott P; Erdos MR; Estrada K; Ferrucci L; Fischer G; Forouhi NG; Gieger C; Grallert H; Groves CJ; Grundy S; Guiducci C; Hadley D; Hamsten A; Havulinna AS; Hofman A; Holle R; Holloway JW; Illig T; Isomaa B; Jacobs LC; Jameson K; Jousilahti P; Karpe F; Kuusisto J; Laitinen J; Lathrop GM; Lawlor DA; Mangino M; McArdle WL; Meitinger T; Morken MA; Morris AP; Munroe P; Narisu N; Nordstrom A; Nordstroem P; Oostra BA; Palmer CNA; Payne F; Peden JF; Prokopenko I; Renstroem F; Ruokonen A; Salomaa V; Sandhu MS; Scott LJ; Scuteri A; Silander K; Song K; Yuan X; Stringham HM; Swift AJ; Tuomi T; Uda M; Vollenweider P; Waeber G; Wallace C; Walters GB; Weedon MN; Witteman JCM; Zhang C; Zhang W; Caulfield MJ; Collins FS; Smith GD; Day INM; Franks PW; Hattersley AT; Hu FB; Jarvelin M-R; Kong A; Kooner JS; Laakso M; Lakatta E; Mooser V; Morris AD; Peltonen L; Samani NJ; Spector TD; Strachan DP; Tanaka T; Tuomilehto J; Uitterlinden AG; van Duijn CM; Wareham NJ; Watkins H; Waterworth DM; Boehnke M; Deloukas P; Groop L; Hunter DJ; Thorsteinsdottir U; Schlessinger D; Wichmann H-E; Frayling TM; Abecasis GR; Hirschhorn JN; Loos RJF; Stefansson K; Mohlke KL; Barroso IS; McCarthy MI
Article: NATURE GENETICS. 2009;41(6):666-676
Genome-wide association study identifies eight loci associated with blood pressure
Newton-Cheh C; Johnson T; Gateva V; Tobin MD; Bochud M; Coin L; Najjar SS; Zhao JH; Heath SC; Eyheramendy S; Papadakis K; Voight BF; Scott LJ; Zhang F; Farrall M; Tanaka T; Wallace C; Chambers JC; Khaw K-T; Nilsson P; van der Harst P; Polidoro S; Grobbee DE; Onland-Moret NC; Bots ML; Wain LV; Elliott KS; Teumer A; Luan J; Lucas G; Kuusisto J; Burton PR; Hadley D; McArdle WL; Brown M; Dominiczak A; Newhouse SJ; Samani NJ; Webster J; Zeggini E; Beckmann JS; Bergmann S; Lim N; Song K; Vollenweider P; Waeber G; Waterworth DM; Yuan X; Groop L; Orho-Melander M; Allione A; Di Gregorio A; Guarrera S; Panico S; Ricceri F; Romanazzi V; Sacerdote C; Vineis P; Barroso I; Sandhu MS; Luben RN; Crawford GJ; Jousilahti P; Perola M; Boehnke M; Bonnycastle LL; Collins FS; Jackson AU; Mohlke KL; Stringham HM; Valle TT; Willer CJ; Bergman RN; Morken MA; Doering A; Gieger C; Illig T; Meitinger T; Org E; Pfeufer A; Wichmann HE; Kathiresan S; Marrugat J; O'Donnell CJ; Schwartz SM; Siscovick DS; Subirana I; Freimer NB; Hartikainen A-L; McCarthy MI; O'Reilly PF; Peltonen L; Pouta A; de Jong PE; Snieder H; van Gilst WH; Clarke R; Goel A; Hamsten A; Peden JF; Seedorf U; Syvanen A-C; Tognoni G; Lakatta EG; Sanna S; Scheet P; Schlessinger D; Scuteri A; Doerr M; Ernst F; Felix SB; Homuth G; Lorbeer R; Reffelmann T; Rettig R; Voelker U; Galan P; Gut IG; Hercberg S; Lathrop GM; Zelenika D; Deloukas P; Soranzo N; Williams FM; Zhai G; Salomaa V; Laakso M; Elosua R; Forouhi NG; Volzke H; Uiterwaal CS; van der Schouw YT; Numans ME; Matullo G; Navis G; Berglund G; Bingham SA; Kooner JS; Connell JM; Bandinelli S; Ferrucci L; Watkins H; Spector TD; Tuomilehto J; Altshuler D; Strachan DP; Laan M; Meneton P; Wareham NJ; Uda M; Jarvelin M-R; Mooser V; Melander O; Loos RJF; Elliott P; Abecasis GR; Caulfield M; Munroe PB
Article: THROMBOSIS AND HAEMOSTASIS. 2009;101(5):943-953
Variants in the coagulation factor 2 receptor (F2R) gene influence the risk of myocardial infarction in men through an interaction with interleukin 6 serum levels
Gigante B; Vikstrom M; Meuzelaar LS; Chernogubova E; Silveira A; van't Hooft F; Hamsten A; de Faire U
Article: CIRCULATION. GENOMIC AND PRECISION MEDICINE. 2009;2(2):142-150
Novel Associations of CPS1, MUT, NOX4, and DPEP1 With Plasma Homocysteine in a Healthy Population A Genome-Wide Evaluation of 13 974 Participants in the Women's Genome Health Study
Pare G; Chasman DI; Parker AN; Zee RRY; Malarstig A; Seedorf U; Collins R; Watkins H; Hamsten A; Miletich JP; Ridker PM
Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY (EJE). 2009;160(4):593-602
Genetic variation in the ADIPOR2 gene is associated with liver fat content and its surrogate markers in three independent cohorts
Kotronen A; Yki-Jarvinen H; Aminoff A; Bergholm R; Pietilainen KH; Westerbacka J; Talmud PJ; Humphries SE; Hamsten A; Isomaa B; Groop L; Orho-Melander M; Ehrenborg E; Fisher RM
Article: JOURNAL OF MOLECULAR MEDICINE. 2009;87(4):337-346
Genetic variants of TNFSF4 and risk for carotid artery disease and stroke
Olofsson PS; Soderstrom LA; Jern C; Sirsjoe A; Ria M; Sundler E; de Faire U; Wiklund PG; Ohrvik J; Hedin U; Paulsson-Berne G; Hamsten A; Eriksson P; Hansson GK
Article: JOURNAL OF INTERNAL MEDICINE. 2009;265(3):373-381
Association of genetic variation on chromosome 9p21.3 and arterial stiffness
Bjorck HM; Lanne T; Alehagen U; Persson K; Rundkvist L; Hamsten A; Dahlstrom U; Eriksson P
Article: CLINICAL SCIENCE. 2009;116(5-6):507-512
IGF-I/IGFBP-3 ratio: a mechanistic insight into the metabolic syndrome
Sierra-Johnson J; Romero-Corral A; Somers VK; Lopez-Jimenez F; Malarstig A; Brismar K; Hamsten A; Fisher RM; Hellenius M-L
Article: ATHEROSCLEROSIS. 2009;202(2):550-556
Gender specific associations between matrix metalloproteinases and inflammatory markers in post myocardial infarction patients
Samnegarda A; Hulthe J; Silveira A; Ericsson C-G; Hamsten A; Eriksson P
Article: DIABETES CARE. 2009;32(2):317-322
Peripheral Sensory Neuropathy Associates With Micro- or Macroangiopatly Results from a population-based study of type 2 diabetic patients in Sweden
Karvestedt L; Martensson E; Grill V; Elofsson S; von Wendt G; Hamsten A; Brismar K
Article: EUROPEAN HEART JOURNAL. 2008;29(18):2218-2226
High plasma concentrations of autoantibodies against native peptide 210 of apoB-100 are related to less coronary atherosclerosis and lower risk of myocardial infarction
Sjogren P; Fredrikson GN; Samnegard A; Ericsson C-G; Ohrvik J; Fisher RM; Nilsson J; Hamsten A
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2008;295(1):E85-E91
Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy-associated lipodystrophy
Sevastianova K; Sutinen J; Kannisto K; Hamsten A; Ristola M; Yki-Jarvinen H
Article: HEART. 2008;94(6):724-729
Raised interleukin-10 is an indicator of poor outcome and enhanced systemic inflammation in patients with acute coronary syndrome
Malarstig A; Eriksson P; Hamsten A; Lindahl B; Wallentin L; Siegbahn A
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2008;21(6):697-704
Expression profiling of macrophages from subjects with atherosclerosis to identify novel susceptibility genes
Hagg DA; Jernas M; Wiklund O; Thelle DS; Fagerberg B; Eriksson P; Hamsten A; Olsson B; Carlsson B; Carlsson LMS; Svensson P-A
Article: JOURNAL OF INTERNAL MEDICINE. 2008;263(5):538-552
Identifying the susceptibility genes for coronary artery disease: from hyperbole through doubt to cautious optimism
Hamsten A; Eriksson P
Article: CLINICAL CHEMISTRY. 2008;54(5):833-840
Genetic variants of tumor necrosis factor superfamily, member 4 (TNFSF4), and risk of incident atherothrombosis and venous thromboembolism
Maelarstig A; Eriksson P; Rose L; Diehl KA; Hamsten A; Ridker PM; Zee RYL
Article: AMERICAN JOURNAL OF PHYSIOLOGY - GASTROINTESTINAL AND LIVER PHYSIOLOGY. 2008;294(5):G1281-G1287
Gene expression in human NAFLD
Greco D; Kotronen A; Westerbacka J; Puig O; Arkkila P; Kiviluoto T; Laitinen S; Kolak M; Fisher RM; Hamsten A; Auvinen P; Yki-Jarvinen H
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2008;28(5):975-982
Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction
Malarstig A; Sigurdsson S; Eriksson P; Paulsson-Berne G; Hedin U; Wallentin L; Siegbahn A; Hamsten A; Syvanen A-C
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2008;93(5):1995-2001
Insulin-induced gene 2 involvement in human adipocyte metabolism and body weight regulation
Krapivner S; Popov S; Chernogubova E; Hellenius M-L; Fisher RM; Hamsten A; van't Hooft FM
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2008;294(5):E841-E845
Insulin regulation of MCP-1 in human adipose tissue of obese and lean women
Westerbacka J; Corner A; Kolak M; Makkonen J; Turpeinen U; Hamsten A; Fisher RM; Yki-Jarvinen H
Article: HUMAN MOLECULAR GENETICS. 2008;17(6):806-814
Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
Broadbent HM; Peden JF; Lorkowski S; Goel A; Ongen H; Green F; Clarke R; Collins R; Franzosi MG; Tognoni G; Seedorf U; Rust S; Eriksson P; Hamsten A; Farrall M; Watkins H
Article: PLOS GENETICS. 2008;4(3):e1000036
Transcriptional profiling uncovers a network of cholesterol-responsive atherosclerosis target genes
Skogsberg J; Lundstrom J; Kovacs A; Nilsson R; Noori P; Maleki S; Kohler M; Hamsten A; Tegner J; Bjorkegren J
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 2008;57(3):362-366
Autoantibodies against modified apolipoprotein B-100 in relation to low-density lipoprotein size and the metabolic syndrome in otherwise healthy men
Sjogren P; Fredrikson GN; Rosell M; de Faire U; Hamsten A; Nilsson J; Hellenius M-L; Fisher RM
Article: ATHEROSCLEROSIS. 2008;196(2):514-522
ADAMTS-4 and-8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques
Wagsater D; Bjork H; Zhu C; Bjorkegren J; Valen G; Hamsten A; Eriksson P
Article: DIABETOLOGIA. 2008;51(2):328-335
Fatty acid desaturases in human adipose tissue:: relationships between gene expression, desaturation indexes and insulin resistance
Sjogren P; Sierra-Johnson J; Gertow K; Rosell M; Vessby B; de Faire U; Hamsten A; Hellenius M-L; Fisher RM
Article: CLINICAL ENDOCRINOLOGY. 2008;68(1):51-58
Correlation of serum lGF-I and IGFBP-1 and-3 to cardiovascular risk indicators and early carotid atherosclerosis in healthy middle-aged men
Boquist S; Ruotolo G; Skoglund-Andersson C; Tang R; Bjorkegren J; Bond MG; de Faire U; Brismar K; Hamsten A
Article: PLOS ONE. 2008;3(11):e3771
ApoB100-LDL Acts as a Metabolic Signal from Liver to Peripheral Fat Causing Inhibition of Lipolysis in Adipocytes
Skogsberg J; Dicker A; Ryden M; Astrom G; Nilsson R; Bhuiyan H; Vitols S; Mairal A; Langin D; Alberts P; Walum E; Tegner J; Hamsten A; Arner P; Bjorkegren J
Article: THROMBOSIS AND HAEMOSTASIS. 2007;98(6):1246-1251
APC resistance during the normal menstrual cycle
van Rooijen M; Silveira A; Thomassen S; Odeberg J; Hamsten A; Rosing J; Bremme K
Article: ATHEROSCLEROSIS. 2007;195(2):e168-e175
Markers of endothelial activity are related to components of the metabolic syndrome, but not to circulating concentrations of the advanced glycation end-product Nε-carboxymethyl-lysine in healthy Swedish men
Sjogren P; Basta G; de Caterina R; Rosell M; Basu S; Silveira A; de Faire U; Vessby B; Hamsten A; Hellenius M-L; Fisher RM
Article: JOURNAL OF INTERNAL MEDICINE. 2007;262(5):545-554
Cardiomyopathy, pericarditis and myocarditis in a population-based cohort of inpatients with coeliac disease
Elfstrom P; Hamsten A; Montgomery SM; Ekbom A; Ludvigsson JF
Article: JOURNAL OF HYPERTENSION. 2007;25(11):2301-2307
Decreased flow-mediated dilation is present 1 year after a pre-eclamptic pregnancy
Hamad RR; Eriksson MJ; Silveira A; Hamsten A; Bremme K
Article: EUROPEAN HEART JOURNAL. 2007;28(21):2637-2643
ApoB/apoA-1 ratio:: an independent predictor of insulin resistance in US non-diabetic subjects
Sierra-Johnson J; Romero-Corral A; Somers VK; Lopez-Jimenez F; Walldius G; Hamsten A; Hellenius M-L; Fisher RM
Article: DIABETES. 2007;56(11):2759-2765
Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects
Westerbacka J; Kolak M; Kiviluoto T; Arkkila P; Siren J; Hamsten A; Fisher RM; Yki-Jaervinen H
Article: INTERNATIONAL JOURNAL OF OBESITY. 2007;31(10):1617-1625
Increased expression of the macrophage markers and of 11β-HSD-1 in subcutaneous adipose tissue, but not in cultured monocyte-derived macrophages, is associated with liver fat in human obesity
Makkonen J; Westerbacka J; Kolak M; Sutinen J; Corner A; Hamsten A; Fisher RM; Yki-Jarvinen H
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2007;27(10):2250-2257
Association of plasminogen activator inhibitor (PAI)-1 (SERPINE1) SNPs with myocardial infarction, plasma PAI-1, and metabolic parameters - The HIFMECH study
Morange PE; Saut N; Alessi MC; Yudkin JS; Margaglione M; Di Minno G; Hamsten A; Humphries SE; Tregouet DA; Juhan-Vague I
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(34):13768-13773
Human C-reactive protein slows atherosclerosis development in a mouse model with human-like hypercholesterolemia
Kovacs A; Tornvall P; Nilsson R; Tegner J; Hamsten A; Bjorkegren J
Article: BMC MOLECULAR BIOLOGY. 2007;8:70
Alternative splicing of human peroxisome proliferator-activated receptor delta (PPARdelta): effects on translation efficiency and trans-activation ability
Lundell K; Thulin P; Hamsten A; Ehrenborg E
Article: THROMBOSIS AND HAEMOSTASIS. 2007;98(2):427-433
Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms
Folkesson M; Kazi M; Zh C; Silveira A; Hemclahl A-L; Harristen A; Hedin U; Swedenborg J; Eriksson P
Article: DIABETES. 2007;56(8):1960-1968
Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity
Kolak M; Westerbacka J; Velagapudi VR; Wagsater D; Yetukuri L; Makkonen J; Rissanen A; Hakkinen A-M; Lindell M; Bergholm R; Hamsten A; Eriksson P; Fisher RM; Oresic M; Yki-Jarvinen H
Article: ATHEROSCLEROSIS. 2007;193(2):321-327
Post-prandial endothelial dysfunction in hypertriglyceridemic subjects: Molecular mechanisms and gene expression studies
Norata GD; Grigore L; Raselli S; Redaelli L; Hamsten A; Maggi F; Eriksson P; Catapano AL
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2007;5(4):766-773
Elevated plasma fibrinogen γ′ concentration is associated with myocardial infarction:: effects of variation in fibrinogen genes and environmental factors
Mannila MN; Lovely RS; Kazmierczak SC; Eriksson P; Samnegard A; Farrell DH; Hamsten A; Silveira A
Article: NUTRITION, METABOLISM AND CARDIOVASCULAR DISEASES. 2007;17(3):195-202
A high-fat meat is accompanied by increased plasma interleukin-6 concentrations
Lundman P; Boquist S; Samnegard A; Bennermo M; Held C; Ericsson C-G; Silveira A; Hamsten A; Tornvall P
Article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2007;15(2):221-227
Multiple QTL influence the serum Lp(a) concentration: a genome-wide linkage screen in the PROCARDIS study
Barlera S; Specchia C; Farrall M; Chiodini BD; Franzosi MG; Rust S; Green F; Nicolis EB; Peden J; Assmann G; Collins R; Hamsten A; Tognoni G; Watkins H
Article: JOURNAL OF INTERNAL MEDICINE. 2007;261(2):138-147
The association between fibrinogen haplotypes and myocardial infarction in men is partly mediated through pleiotropic effects on the serum IL-6 concentration
Mannila MN; Eriksson P; Leander K; Wiman B; de Faire U; Hamsten A; Silveira A
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2007;92(2):720-724
Effects of chronic rosiglitazone therapy on gene expression in human adipose tissue in vivo in patients with type 2 diabetes
Kolak M; Yki-Jarvinen H; Kannisto K; Tiikkainen M; Hamsten A; Eriksson P; Fisher RM
Article: DIABETOLOGIA. 2007;50(1):94-102
Human evidence for the involvement of insulin-induced gene 1 in the regulation of plasma glucose concentration
Krapivner S; Chernogubova E; Ericsson M; Ahlbeck-Glader C; Hamsten A; van't Hooft FM
Article: THROMBOSIS RESEARCH. 2007;120(5):653-661
Beneficial effects of dalteparin on haemostatic function and local tissue oxygenation in patients with diabetes, severe vascular disease and foot ulcers
Kalani M; Silveira A; Blomback M; Apelqvist J; Eliasson B; Eriksson JW; Fagrell B; Torffvit O; Hamsten A; Jorneskog G
Article: THROMBOSIS AND HAEMOSTASIS. 2007;97(1):15-20
Rapid activation of haemostasis after hormonal emergency contraception
von Rooijen M; Silveira A; Thomassen S; Hansson L-O; Rosing J; Hamsten A; Bremme K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;351(3):777-783
Allele-specific chromatin remodeling of the tumor necrosis factor-α promoter
Skoog T; Hamsten A; Eriksson P
Article: EUROPEAN JOURNAL OF CLINICAL NUTRITION. 2006;60(12):1406-1413
Fatty acid handling protein expression in adipose tissue, fatty acid composition of adipose tissue and serum, and markers of insulin resistance
Gertow K; Rosell M; Sjogren P; Eriksson P; Vessby B; de Faire U; Hamsten A; Hellenius M-L; Fisher RM
Article: ATHEROSCLEROSIS. 2006;188(2):450-454
Plasma interleukin (IL)-18 concentrations is elevated in patients with previous myocardial infarction and related-to severity of coronary atherosclerosis independently of C-reactive protein and IL-6
Hulthe J; McPheat W; Samnegard A; Tornvall P; Hamsten A; Eriksson P
Article: ATHEROSCLEROSIS. 2006;188(2):462-466
Decreased plasma CXCL16/SR-PSOX concentration is associated with coronary artery disease
Sheikine Y; Bang CS; Nilsson L; Samnegard A; Hamsten A; Jonasson L; Eriksson P; Sirsjo A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;348(3):1150-1156
Allele-specific MMP-3 transcription under in vivo conditions
Zhu C; Odeberg J; Hamsten A; Eriksson P
Article: CLINICAL CHEMISTRY. 2006;52(8):1522-1527
Increased plasma concentration of matrix metalloproteinase-7 in patients with coronary artery disease
Nilsson L; Jonasson L; Nijm J; Hamsten A; Eriksson P
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2006;35(4):922-931
Insight into the nature of the CRP-coronary event association using Mendelian randomization
Casas JP; Shah T; Cooper J; Hawe E; McMahon AD; Gaffney D; Packard CJ; O'Reilly DS; Juhan-Vague I; Yudkin JS; Tremoli E; Margaglione M; Di Minno G; Hamsten A; Kooistra T; Stephens JW; Hurel SJ; Livingstone S; Colhoun HM; Miller GJ; Bautista LE; Meade T; Sattar N; Humphries SE; Hingorani AD
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2006;91(7):2776-2781
Acquired obesity increases CD68 and tumor necrosis factor-α and decreases adiponectin gene expression in adipose tissue:: A study in monozygotic twins
Pietilainen KH; Kannisto K; Korsheninnikova E; Rissanen A; Kaprio J; Ehrenborg E; Hamsten A; Yki-Jarvinen H
Article: JOURNAL OF INTERNAL MEDICINE. 2006;259(5):530-536
Lower serum concentration of matrix metalloproteinase-3 in the acute stage of myocardial infarction
Samnegård A; Silveira A; Tornvall P; Hamsten A; Ericsson CG; Eriksson P
Article: PLOS GENETICS. 2006;2(5):755-761
Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17
Farrall M; Green FR; Peden JF; Olsson PG; Clarke R; Hellenius M-L; Rust S; Lagercrantz J; Franzosi MG; Schulte H; Carey A; Olsson G; Assmann G; Tognoni G; Collins R; Hamsten A; Watkins H
Article: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2006;40(4):484-494
Triglyceride-rich lipoproteins from hypertriglyceridemic subjects induce a pro-inflammatory response in the endothelium: Molecular mechanisms and gene expression studies
Norata GD; Grigore L; Raselli S; Seccomandi PM; Hamsten A; Maggi FM; Eriksson P; Catapano AL
Article: JOURNAL OF AMERICAN ACADEMY OF DERMATOLOGY. 2006;54(4):614-621
Psoriasis is associated with lipid abnormalities at the onset of skin disease
Mallbris L; Granath F; Hamsten A; Ståhle M
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2006;290(4):E739-E745
Microsomal triglyceride transfer protein-493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles
Lundahl B; Skoglund-Andersson C; Caslake M; Bedford D; Stewart P; Hamsten A; Packard CJ; Karpe F
Article: THROMBOSIS AND HAEMOSTASIS. 2006;95(3):420-427
Epistatic and pleiotropic effects of polymorphisms in the fibrinogen and coagulation factor XIII genes on plasma fibrinogen concentration, fibrin gel structure and risk of myocardial infarction
Mannila MN; Eriksson P; Ericsson CG; Hamsten A; Silveira A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2006;339(3):1001-1006
Human genetic evidence that OX40 is implicated in myocardial infarction
Ria M; Eriksson P; Boquist S; Ericsson CG; Hamsten A; Lagercrantz J
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2006;4(1):77-82
Treatment with combined oral contraceptives induces a rise in serum C-reactive protein in the absence of a general inflammatory response
van Rooijen M; Hansson LO; Frostegård J; Silveira A; Hamsten A; Bremme K
Article: DIABETOLOGIA. 2006;49(1):132-140
Acute in vivo effects of insulin on gene expression in adipose tissue in insulin-resistant and insulin-sensitive subjects
Westerbacka J; Cornér A; Kannisto K; Kolak M; Makkonen J; Korsheninnikova E; Nyman T; Hamsten A; Fisher RM; Yki-Järvinen H
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2006;17(1):45-52
Differential expression of peroxisomal proliferator activated receptors α and δ in skeletal muscle in response to changes in diet and exercise
Kannisto K; Chibalin A; Glinghammar B; Zierath JR; Hamsten A; Ehrenborg E
Article: ATHEROSCLEROSIS. 2005;183(2):283-292
EPCR Ser219Gly: Elevated sEPCR, prothrombin F1+2, risk for coronary heart disease, and increased sEPCR shedding in vitro
Ireland H; Konstantoulas CJ; Cooper JA; Hawe E; Humphries SE; Mather H; Goodall AH; Hogwood J; Juhan-Vague I; Yudkin JS; di Minno G; Margaglione M; Hamsten A; Miller GJ; Bauer KA; Kim YT; Stearns-Kurosawa DJ; Kurosawa S
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2005;25(12):2580-2586
Measures of oxidized low-density lipoprotein and oxidative stress are not related and not elevated in otherwise healthy men with the metabolic syndrome
Sjogren P; Basu S; Rosell M; Silveira A; de Faire U; Vessby B; Hamsten A; Hellenius ML; Fisher RM
Article: CIRCULATION RESEARCH. 2005;97(10):1070-1076
Haplotype effect of the matrix metalloproteinase-1 gene on risk of myocardial infarction
Pearce E; Tregouet DA; Samnegård A; Morgan AR; Cox C; Hamsten A; Eriksson P; Ye S
Article: JOURNAL OF INTERNAL MEDICINE. 2005;258(5):411-419
Serum matrix metalloproteinase-3 concentration is influenced by MMP-3-1612 5A/6A promoter genotype and associated with myocardial infarction
Samnegård A; Silveira A; Lundman P; Boquist S; Odeberg J; Hulthe J; Mcpheat W; Tornvall P; Bergstrand L; Ericsson CG; Hamsten A; Eriksson P
Article: DIABETOLOGIA. 2005;48(11):2229-2235
Beta cell dysfunction in patients with acute myocardial infarction but without previously known type 2 diabetes:: a report from the GAMI study
Wallander M; Bartnik M; Efendic S; Hamsten A; Malmberg K; Öhrvik J; Rydén L; Silveira A; Norhammar A
Article: BRITISH JOURNAL OF SURGERY. 2005;92(11):1372-1376
Genotype-phenotype relationships in an investigation of the role of proteases in abdominal aortic aneurysm expansion
Eriksson P; Jormsjö-Pettersson S; Brady AR; Deguchi H; Hamsten A; Powell JT
Article: STROKE. 2005;36(8):1661-1665
Plasminogen activator inhibitor-1 4G/5G polymorphism and risk of stroke - Replicated findings in two nested case-control studies based on independent cohorts
Wiklund PG; Nilsson L; Ardnor SN; Eriksson P; Johansson L; Stegmayr B; Hamsten A; Holmberg D; Asplund K
Article: THROMBOSIS AND HAEMOSTASIS. 2005;94(2):427-431
Genotype-specific increase in plasma concentrations of activated coagulation factor VII in response to experimental inflammation - A link between infection and acute myocardial infarction?
Bennermo M; Held C; Ericsson CG; Silveira A; Hamsten A; Tornvall P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2005;25(7):1341-1346
Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm
Kazi M; Zhu CY; Roy J; Paulsson-Berne G; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Article: CLINICAL CHEMISTRY. 2005;51(5):911-913
Hormonal regulation of circulating C-reactive protein in men
Kovacs A; Henriksson P; Hamsten A; Wallén H; Björkegren J; Tornvall P
Article: JOURNAL OF INTERNAL MEDICINE. 2005;257(5):415-422
Severity of coronary artery stenosis is associated with a polymorphism in the CXCL16/SR-PSOX gene
Lundberg GA; Kellin A; Samnegård A; Lundman P; Tornvall P; Dimmeler S; Zeiher AM; Hamsten A; Hansson GK; Eriksson P
Article: NATURE GENETICS. 2005;37(5):486-494
MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction
Swanberg M; Lidman O; Padyukov L; Eriksson P; Åkesson E; Jagodic M; Lobell A; Khademi M; Borjesson O; Lindgren CM; Lundman P; Brookes AJ; Kere J; Luthman H; Alfredsson L; Hillert J; Klareskog L; Hamsten A; Piehl F; Olsson T
Article: REGULATORY PEPTIDES. 2005;127(1-3):45-53
Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index:: possible mode of function
Ding B; Kull B; Liu ZR; Mottagui-Tabar S; Thonberg H; Gu HF; Brookes AJ; Grundemar L; Karlsson C; Hamsten A; Arner P; Östenson CG; Efendic S; Monné M; von Heijne G; Eriksson P; Wahlestedt C
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2005;45(7):1013-1017
The apolipoprotein Cl content of triglyceride-rich lipoproteins independently predicts early atherosclerosis in healthy middle-aged men
Hamsten A; Silveira A; Boquist S; Tang R; Bond MG; de Faire U; Björkegren J
Article: ATHEROSCLEROSIS. 2005;179(2):317-323
Interaction between the C-260T polymorphism of the CD14 gene and the plasma IL-6 concentration on the risk of myocardial infarction:: the HIFMECH study
Morange PE; Saut N; Alessi MC; Frere C; Hawe E; Yudkin JS; Tremoli E; Margaglione M; Di Minno G; Hamsten A; Humphries SE; Juhan-Vague I
Article: NATURE GENETICS. 2005;37(4):365-372
Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility
Wang XS; Ria M; Kelmenson PM; Eriksson P; Higgins DC; Samnegård C; Petros C; Rollins J; Bennet AM; Wiman B; de Faire U; Wennberg C; Olsson PG; Ishii N; Sugamura K; Hamsten A; Forsman-Semb K; Lagercrantz J; Paigen B
Article: EUROPEAN HEART JOURNAL. 2005;26(7):650-661
FASTTRACK Intense metabolic control by means of insulin in patients with diabetes mellitus and acute myocardial infarction (DIGAMI 2):: effects on mortality and morbidity
Malmberg K; Rydén L; Wedel H; Birkeland K; Bootsma A; Dickstein K; Efendic S; Fisher M; Hamsten A; Herlitz J; Hildebrandt P; MacLeod K; Laakso M; Torp-Pedersen C; Waldenström A
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(3):570-577
Contribution of haplotypes across the fibrinogen gene cluster to variation in risk of myocardial infarction
Mannila MN; Eriksson P; Lundman P; Samnegård A; Boquist S; Ericsson CG; Tornvall P; Hamsten A; Silveira A
Article: THROMBOSIS AND HAEMOSTASIS. 2005;93(2):351-358
Influence of factor VII gene polymorphisms and environmental factors on plasma coagulation factor VII concentrations in middle-aged women with and without manifest coronary heart disease
Eriksson-Berg M; Deguchi H; Hawe E; Scanavini D; Orth-Gomér K; Schenck-Gustafsson K; Humphries SE; Silveira A; Hamsten A
Article: ATHEROSCLEROSIS. 2005;178(1):193-198
A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein
Kovacs A; Green F; Hansson LO; Lundman P; Samnegård A; Boquist S; Ericsson CG; Watkins HH; Hamsten A; Tornvall P
Article: CARDIOLOGY. 2005;104(2):65-71
Plasma C-reactive protein and lipoprotein levels, and progression of coronary artery disease after myocardial infarction treated with thrombolysis
Tornvall P; Hamsten A; Hansson LO; O'Konor ML; Ericsson CG; Strandberg LE; Boavida A; Bergstrand L
Article: THROMBOSIS AND HAEMOSTASIS. 2004;92(6):1240-1249
Plasma fibrinogen concentration predicts the risk of myocardial infarction differently in various parts of Europe:: Effects of β-fibrinogen genotype and environmental factors -: The HIFMECH Study
Mannila MN; Silveira A; Hawe E; Eriksson P; Aillaud MF; Juhan-Vague I; Yudkin J; Margaglione M; di Minno G; Mussoni L; Tremoli E; Humphries S; Hamsten A
Article: ATHEROSCLEROSIS. 2004;177(2):443-450
Locating Ath8, a locus for murine atherosclerosis susceptibility and testing several of its candidate genes in mice and humans
Korstanje R; Eriksson P; Samnegård A; Olsson PG; Forsman-Semb K; Sen S; Churchill GA; Rollins J; Harris S; Hamsten A; Paigen B
Article: DIABETOLOGIA. 2004;47(10):1668-1671
In the lipodystrophy associated with highly active antiretroviral therapy, pseudo-Cushing's syndrome is associated with increased regeneration of cortisol by 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue
Sutinen J; Kannisto K; Korsheninnikova E; Nyman T; Ehrenborg E; Andrew R; Wake DJ; Hamsten A; Walker BR; Yki-Järvinen H
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2004;127(1):97-104
Oxidised-HDL₃ induces the expression of PAI-1 in human endothelial cells.: Role of p38MAPK activation and mRNA stabilization
Norata GD; Banfi C; Pirillo A; Tremoli E; Hamsten A; Catapano AL; Eriksson P
Article: JOURNAL OF INTERNAL MEDICINE. 2004;256(4):288-297
Abnormal glucose tolerance -: a common risk factor in patients with acute myocardial infarction in comparison with population-based controls
Bartnik M; Malmberg K; Hamsten A; Efendic S; Norhammar A; Silveira A; Tenerz Å; Öhrvik J; Rydén L
Article: JOURNAL OF LIPID RESEARCH. 2004;45(9):1768-1776
Effect of macrophage differentiation and exposure to mildly oxidized LDL on the proteolytic repertoire of THP-1 monocytes
Whatling C; Björk H; Gredmark S; Hamsten A; Eriksson P
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2004;89(9):4414-4421
Overexpression of 11β-hydroxysteroid dehydrogenase-1 in adipose tissue is associated with acquired obesity and features of insulin resistance:: Studies in young adult monozygotic twins
Kannisto K; Pietiläinen KH; Ehrenborg E; Rissanen A; Kaprio J; Hamsten A; Yki-Järvinen H
Article: EUROPEAN HEART JOURNAL. 2004;25(16):1447-1453
Association of hypo-responsive toll-like receptor 4 variants with risk of myocardial infarction
Edfeldt K; Bennet AM; Eriksson P; Frostegård J; Wiman B; Hamsten A; Hansson GK; de Faire U; Yan ZQ
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 2004;53(7):852-857
Low-grade inflammation may play a role in the etiology of the metabolic syndrome in patients with coronary heart disease: The HIFMECH study
Yudkin JS; Juhan-Vague I; Hawe E; Humphries SE; di Minno G; Margaglione M; Tremoli E; Kooistra T; Morange PE; Lundman P; Mohamed-Ali V; Hamsten A
Article: DIABETOLOGIA. 2004;47(6):1118-1125
Expression of fatty-acid-handling proteins in human adipose tissue in relation to obesity and insulin resistance
Gertow K; Pietiläinen KH; Yki-Järvinen H; Kaprio J; Rissanen A; Eriksson P; Hamsten A; Fisher RM
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2004;286(6):E941-E949
Effects of rosiglitazone on gene expression in subcutaneous adipose tissue in highly active antiretroviral therapy-associated lipodystrophy
Sutinen J; Kannisto K; Korsheninnikova E; Fisher RM; Ehrenborg E; Nyman T; Virkamäki A; Funahashi T; Matsuzawa Y; Vidal H; Hamsten A; Yki-Järvinen H
Article: ATHEROSCLEROSIS. 2004;174(1):157-163
Prognostic value of plasma interleukin-6 concentrations and the -174 G>C and -572 G>C promoter polymorphisms of the interleukin-6 gene in patients with acute myocardial infarction treated with thrombolysis
Bennermo M; Held C; Green F; Strandberg LE; Ericsson CG; Hansson LO; Watkins H; Hamsten A; Tornvall P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2004;24(3):551-557
Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease
Eriksson P; Deguchi H; Samnegård A; Lundman P; Boquist S; Tornvall P; Ericsson CG; Bergstrand L; Hansson LO; Ye S; Hamsten A
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2004;190(2):332-337
Sex hormone-binding globulin-A surrogate marker for the prothrombotic effects of combined oral contraceptives
van Rooijen M; Silveira A; Hamsten A; Bremme K
Article: MATRIX BIOLOGY. 2004;22(7):557-560
High-density lipoprotein subfraction 3 decreases ADAMTS-1 expression induced by lipopolysaccharide and tumor necrosis factor-α in human endothelial cells
Norata GD; Björk H; Hamsten A; Catapano AL; Eriksson P
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY AND METABOLISM (JCEM). 2004;89(1):392-399
Genetic and structural evaluation of fatty acid transport protein-4 in relation to markers of the insulin resistance syndrome
Gertow K; Bellanda M; Eriksson P; Boquist S; Hamsten A; Sunnerhagen M; Fisher RM
Article: JOURNAL OF INTERNAL MEDICINE. 2003;254(6):597-604
Peroxisome proliferator activated receptor delta genotype in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men
Skogsberg J; McMahon AD; Karpe F; Hamsten A; Packard CJ; Ehrenborg E
Article: BLOOD COAGULATION AND FIBRINOLYSIS. 2003;14(8):749-753
No evidence that the PLA1/PLA2 polymorphism of platelet glycoprotein IIIa is implicated in angiographically characterized coronary atherosclerosis and premature myocardial infarction
Lagercrantz J; Bergman M; Lundman P; Tornvall P; Hjemdahl P; Hamsten A; Eriksson P
Article: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. 2003;1(11):2322-2329
The plasminogen activator inhibitor-1-675 4G/5G genotype influences the risk of myocardial infarction associated with elevated plasma proinsulin and insulin concentrations in men from Europe: the HIFMECH Study
Juhan-Vague I; Morange PE; Frere C; Aillaud MF; Alessi MC; Hawe E; Boquist S; Tornvall P; Yudkin JS; Tremoli E; Margaglione M; Di Minno G; Hamsten A; Humphries SE
Article: DIABETES CARE. 2003;26(10):2770-2776
Diabetes, insulin resistance, and the metabolic syndrome in patients with acute myocardial infarction without previously known diabetes
Tenerz Å; Norhammar A; Silveira A; Hamsten A; Nilsson G; Rydén L; Malmberg K
Article: DIABETES CARE. 2003;26(9):2575-2580
Effect of dalteparin on healing of chronic foot ulcers in diabetic patients with peripheral arterial occlusive disease - A prospective, randomized, double-blind, placebo-controlled study
Kalani M; Apelqvist J; Blombäck M; Brismar K; Eliasson B; Eriksson JW; Fagrell B; Hamsten A; Torffvit O; Jörneskog G
Article: JOURNAL OF INTERNAL MEDICINE. 2003;254(3):244-250
Prognostic value of plasma C-reactive protein and fibrinogen determinations in patients with acute myocardial infarction treated with thrombolysis
Bennermo M; Held C; Hamsten A; Strandberg LE; Ericsson CG; Hansson LO; Tornvall P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2003;308(2):361-368
PPARδ activation induces COX-2 gene expression and cell proliferation in human hepatocellular carcinoma cells
Glinghammar B; Skogsberg J; Hamsten A; Ehrenborg E
Article: AIDS. 2003;17(12):1753-1762
Expression of adipogenic transcription factors, peroxisome proliferator-activated receptor gamma co-activator 1, IL-6 and CD45 in subcutaneous adipose tissue in lipodystrophy associated with highly active antiretroviral therapy
Kannisto K; Sutinen J; Korsheninnikova E; Fisher RM; Ehrenborg E; Gertow K; Virkamäki A; Nyman T; Vidal H; Hamsten A; Yki-Järvinen H
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2003;12(1):73-78
Effects of HDL₃ on the expression of matrix-degrading proteases in human endothelial cells
Norata GD; Pellegatta F; Hamsten A; Catapano AL; Eriksson P
Article: CARDIOVASCULAR RESEARCH (CVR). 2003;59(1):169-180
Gene expression and intracellular pathways involved in endothelial dysfunction induced by VLDL and oxidised VLDL
Norata GD; Pirillo A; Callegari E; Hamsten A; Catapano AL; Eriksson P
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2003;91(9):1128-1131
Relation of hypertriglyceridemia to plasma concentrations of biochemical markers of inflammation and endothelial activation (C-reactive protein, interleukin-6, soluble adhesion molecules, von Willebrand factor, and endothelin-1)
Lundman P; Eriksson MJ; Silveira A; Hansson LO; Pernow J; Ericsson CG; Hamsten A; Tornvall P
Article: CIRCULATION. 2003;107(13):1733-1737
Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease - The Diabetes Atherosclerosis Intervention Study (DAIS)
Vakkilainen J; Steiner G; Ansquer JC; Aubin F; Rattier S; Foucher C; Hamsten A; Taskinen MR
Article: ATHEROSCLEROSIS. 2003;167(2):347-353
Autoantibodies against modified low-density lipoproteins in coronary artery disease
Tornvall P; Waeg G; Nilsson J; Hamsten A; Regnström J
Article: ATHEROSCLEROSIS. 2003;167(2):311-317
Influence of common variants in the CETP, LPL, HL and APO E genes on LDL heterogeneity in healthy, middle-aged men
Skoglund-Andersson C; Ehrenborg E; Fisher RM; Olivercrona G; Hamsten A; Karpe F
Article: ATHEROSCLEROSIS. 2003;167(2):265-273
A common polymorphism in the fatty acid transport protein-1 gene associated with elevated post-prandial lipaemia and alterations in LDL particle size distribution
Gertow K; Skoglund-Andersson C; Eriksson P; Boquist S; Orth-Gomér K; Schenck-Gustafsson K; Hamsten A; Fisher RM
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2003;23(4):637-643
Evidence that peroxisome proliferator-activated receptor delta influences cholesterol metabolism in men
Skogsberg J; Kannisto K; Cassel TN; Hamsten A; Eriksson P; Ehrenborg E
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2003;23(4):688-694
Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy
Yki-Järvinen H; Sutinen J; Silveira A; Korsheninnikova E; Fisher RM; Kannisto K; Ehrenborg E; Eriksson P; Hamsten A
Article: LAKARTIDNINGEN. 2003;100(8):631-632
[The proposal of the National Board of Health and Welfare counteracts knowledge development within health care].
Klareskog L; Efendic S; Brismar K; Hamsten A
Article: LUPUS. 2003;12(6):454-461
TNF-α:: a link between hypertriglyceridaemia and inflammation in SLE patients with cardiovascular disease
Svenungsson E; Fei GZ; Jensen-Urstad K; de Faire U; Hamsten A; Frostegård J
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 2003;33(1):51-57
In vitro and in vivo lipolysis of plasma triglycerides increases the resistance to oxidative modification of low-density lipoproteins
Skoglund-Andersson C; Karpe F; Hellénius ML; Regnström J; Hamsten A; Tornvall P
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2002;239(1-2):95-100
Fatty acid binding protein expression in different human adipose tissue depots in relation to rates of lipolysis and insulin concentration in obese individuals
Fisher RM; Thörne A; Hamsten A; Arner P
Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(3):939-945
Differential expression of cysteine and aspartic proteases during progression of atherosclerosis in apolipoprotein E-deficient mice
Jormsjö S; Wuttge DM; Sirsjö A; Whatling C; Hamsten A; Stemme S; Eriksson P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2002;22(9):1470-1474
Postprandial enrichment of remnant lipoproteins with ApoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis
Björkegren J; Silveira A; Boquist S; Tang R; Karpe F; Bond MG; de Faire U; Hamsten A
Article: THE LANCET. 2002;359(9324):2140-2144
Glucose metabolism in patients with acute myocardial infarction and no previous diagnosis of diabetes mellitus: a prospective study
Norhammar A; Tenerz Å; Nilsson G; Hamsten A; Efendíc S; Rydén L; Malmberg K
Article: ATHEROSCLEROSIS. 2002;162(1):163-170
Effects of atorvastatin on postprandial plasma lipoproteins in postinfarction patients with combined hyperlipidaemia
Boquist S; Karpe F; Danell-Toverud K; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2002;22(5):867-873
Plasma thrombin-activatable fibrinolysis inhibitor antigen concentration and genotype in relation to myocardial infarction in the North and South of Europe
Juhan-Vague I; Morange PE; Aubert H; Henry M; Aillaud MF; Alessi MC; Samnegård A; Hawe E; Yudkin J; Margaglione M; Di Minno G; Hamsten A; Humphries SE
Article: EUROPEAN HEART JOURNAL. 2002;23(5):376-383
Plasma tumour necrosis factor-α and early carotid atherosclerosis in healthy middle-aged men
Skoog T; Dichtl W; Boquist S; Skoglund-Andersson C; Karpe F; Tang R; Bond MG; de Faire U; Nilsson J; Eriksson P; Hamsten A
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 2002;51(3):327-333
Linoleic acid-stimulated vascular adhesion molecule-1 expression in endothelial cells depends on nuclear factor-κB activation
Dichtl W; Ares MPS; Jönson AN; Jovinge S; Pachinger O; Giachelli CM; Hamsten A; Eriksson P; Nilsson J
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2002;22(2):289-293
Postprandial plasma ApoB-48 levels are influenced by a polymorphism in the promoter of the microsomal triglyceride transfer protein gene
Lundahl B; Hamsten A; Karpe F
Article: LUPUS. 2002;11(11):744-752
Cardiac valvular abnormalities are frequent in systemic lupus erythematosus patients with manifest arterial disease
Jensen-Urstad K; Svenungsson E; de Faire U; Silveira A; Witztum JL; Hamsten A; Frostegård J
Article: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2002;186(1):44-48
Different effects of oral contraceptives containing levonorgestrel or desogestrel on plasma lipoproteins and coagulation factor VII
van Rooijen M; von Schoultz B; Silveira A; Hamsten A; Bremme K
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2001;21(11):1834-1839
Allele-specific regulation of matrix metalloproteinase-7 promoter activity is associated with coronary artery luminal dimensions among hypercholesterolemic patients
Jormsjö S; Whatling C; Walter DH; Zeiher AM; Hamsten A; Eriksson P
Article: CIRCULATION. 2001;104(16):1887-1893
Risk factors for cardiovascular disease in systemic lupus erythematosus
Svenungsson E; Jensen-Urstad K; Heimbürger M; Silveira A; Hamsten A; de Faire U; Witztum JL; Frostegård J
Article: DIABETOLOGIA. 2001;44(10):1268-1273
Fatty acid binding protein expression in different adipose tissue depots from lean and obese individuals
Fisher RM; Eriksson P; Hoffstedt J; Hotamisligil GS; Thörne A; Rydén M; Hamsten A; Arner P
Article: CIRCULATION. 2001;104(11):1223-1228
Human evidence that the apolipoprotein A-II gene is implicated in visceral fat accumulation and metabolism of triglyceride-rich lipoproteins
van't Hooft FM; Ruotolo G; Boquist S; de Faire U; Eggertsen G; Hamsten A
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2001;38(1):111-116
Mild-to-moderate hypertriglyceridemia in young men is associated with endothelial dysfunction and increased plasma concentrations of asymmetric dimethylarginine
Lundman P; Eriksson MJ; Stühlinger M; Cooke JP; Hamsten A; Tornvall P
Article: ATHEROSCLEROSIS. 2001;157(1):181-187
Remnant-like lipoprotein particle cholesterol concentration and progression of coronary and vein-graft atherosclerosis in response to gemfibrozil treatment
Karpe F; Taskinen MR; Nieminen MS; Frick MH; Kesäniemi YA; Pasternack A; Hamsten A; Syvänne M
Article: DIABETES. 2001;50(7):1522-1530
Transcriptional regulation of plasminogen activator inhibitor type I gene by insulin - Insights into the signaling pathway
Banfi C; Eriksson P; Giandomenico G; Mussoni L; Sironi L; Hamsten A; Tremoli E
Article: THROMBOSIS AND HAEMOSTASIS. 2001;85(5):787-792
Coagulation factor VII in middle-aged women with and without coronary heart disease
Eriksson-Berg M; Silveira A; Orth-Gomér K; Hamsten A; Schenck-Gustafsson K
Article: THROMBOSIS AND HAEMOSTASIS. 2001;85(4):619-625
Effects of oral and transdermal estrogen replacement therapy on markers of coagulation, fibrinolysis, inflammation and serum lipids and lipoproteins in postmenopausal women
Vehkavaara S; Silveira A; Hakala-Ala-Pietilä T; Virkamäki A; Hovatta O; Hamsten A; Taskinen MR; Yki-Järvinen H
Article: ANNALS OF MEDICINE. 2001;33(2):103-112
Circulating immune complexes induced by food proteins implicated in precocious myocardial infarction
Mustafa A; Hamsten A; Holm G; Lefvert AK
Article: ATHEROSCLEROSIS. 2001;154(3):703-711
Polymorphisms in the thrombopoietin gene are associated with risk of myocardial infarction at a young age
Webb KE; Martin JF; Hamsten A; Eriksson P; Iacoviello L; Gattone M; Donati MB; Di Castelnuovo A; Erusalimsky J; Humphries SE
Article: JOURNAL OF LIPID RESEARCH. 2001;42(1):17-21
Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides
Karpe F; Boquist S; Tang R; Bond GM; de Faire U; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2001;21(1):108-114
LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis
Zhou XH; Caligiuri G; Hamsten A; Lefvert AK; Hansson GK
Article: THROMBOSIS AND HAEMOSTASIS. 2000;84(4):706-711
In vivo stimulation of vascular plasminogen activator inhibitor-1 production by very low-density lipoprotein involves transcription factor binding to a VLDL-responsive element
Dichtl W; Ares MPS; Stollenwerk M; Giachelli CM; Scatena M; Hamsten A; Eriksson P; Nilsson J
Article: THROMBOSIS AND HAEMOSTASIS. 2000;84(3):364-368
Plasma procarboxypeptidase U in men with symptomatic coronary artery disease
Silveira A; Schatteman K; Goossens F; Moor E; Scharpé S; Strömqvist M; Hendriks D; Hamsten A
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2000;6(1):73-81
Characterization of the human peroxisome proliferator activated receptor delta gene and its expression
Skogsberg J; Kannisto K; Roshani L; Gagné E; Hamsten A; Larsson C; Ehrenborg E
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2000;20(7):1835-1841
Plasma lipoproteins enhance tissue factor-independent factor VII activation
Kjalke M; Silveira A; Hamsten A; Hedner U; Ezban M
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2000;20(7):1784-1788
A functional polymorphism in the promoter region of the microsomal triglyceride transfer protein (MTP-493G/T) influences lipoprotein phenotype in familial hypercholesterolemia
Lundahl B; Leren TP; Ose L; Hamsten A; Karpe F
Article: JOURNAL OF INTERNAL MEDICINE. 2000;247(6):651-656
The Q/E27 polymorphism in the β₂-adrenoceptor gene is associated with increased body weight and dyslipoproteinaemia involving triglyceride-rich lipoproteins
Ehrenborg E; Skogsberg J; Ruotolo G; Large V; Eriksson P; Arner P; Hamsten A
Article: CIRCULATION RESEARCH. 2000;86(9):998-1003
Allele-specific regulation of matrix metalloproteinase-12 gene activity is associated with coronary artery luminal dimensions in diabetic patients with manifest coronary artery disease
Jormsjö S; Ye S; Moritz J; Walter DH; Dimmeler S; Zeiher AM; Henney A; Hamsten A; Eriksson P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2000;20(5):1335-1339
Functional characterization of 4 polymorphisms in promoter region of hepatic lipase gene
van 't Hooft FM; Lundahl B; Ragogna F; Karpe F; Olivecrona G; Hamsten A
Article: THROMBOSIS AND HAEMOSTASIS. 2000;83(4):545-548
Regional variation in plasminogen activator inhibitor-1 expression in adipose tissue from obese individuals
Eriksson P; Van Harmelen V; Hoffstedt J; Lundquist P; Vidal H; Stemme V; Hamsten A; Arner P; Reynisdottir S
Article: THROMBOSIS RESEARCH. 2000;98(1):39-49
Haemostatic function in patients undergoing coronary artery bypass grafting:: Peroperative perturbations and relations to saphenous vein graft closure
Moor E; Blombäck M; Silveira A; Wiman B; Cederlund K; Bergstrand L; Ivert T; Rydén L; Hamsten A
Article: THROMBOSIS AND HAEMOSTASIS. 2000;83(3):397-403
Fibrinolytic proteins and progression of coronary artery disease in relation to gemfibrozil therapy
Hamsten A; Syvänne M; Silveira A; Luong LA; Nieminen MS; Humphries S; Frick MH; Taskinen MR
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2000;35(3):647-654
Serum insulin-like growth factor-I level is independently associated with coronary artery disease progression in young male survivors of myocardial infarction:: Beneficial effects of bezafibrate treatment
Ruotolo G; Båvenholm P; Brismar K; Eféndic S; Ericsson CG; de Faire U; Nilsson J; Hamsten A
Article: DIABETOLOGIA. 2000;43(2):185-193
Insulin and non-esterified fatty acid relations to alimentary lipaemia and plasma concentrations of postprandial triglyceride-rich lipoproteins in healthy middle-aged men
Boquist S; Hamsten A; Karpe E; Ruotolo G
Article: CIRCULATION. 2000;101(3):227-230
Accumulation of apolipoprotein C-I-rich and cholesterol-rich VLDL remnants during exaggerated postprandial triglyceridemia in normolipidemic patients with coronary artery disease
Björkegren J; Boquist S; Samnegård A; Lundman P; Tornvall P; Ericsson CG; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1999;19(12):3063-3070
Two common, functional polymorphisms in the promoter region of the β-fibrinogen gene contribute to regulation of plasma fibrinogen concentration
van't Hooft FM; von Bahr SJF; Silveira A; Iliadou A; Eriksson P; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1999;19(12):3025-3032
Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells
Dichtl W; Stiko A; Eriksson P; Goncalves I; Calara F; Banfi C; Ares MPS; Hamsten A; Nilsson J
Article: HUMAN GENETICS. 1999;105(5):418-423
Genetic variation at the matrix metalloproteinase-9 locus on chromosome 20q12.2-13.1
Zhang BP; Henney A; Eriksson P; Hamsten A; Watkins H; Ye S
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1999;19(10):2422-2430
LDL particle size distribution is associated with carotid intima-media thickness in healthy 50-year-old men
Skoglund-Andersson C; Tang R; Bond MG; de Faire U; Hamsten A; Karpe F
Article: JOURNAL OF LIPID RESEARCH. 1999;40(9):1686-1694
A functional polymorphism in the apolipoprotein B promoter that influences the level of plasma low density lipoprotein
van 't Hooft FM; Jormsjö S; Lundahl B; Tornvall P; Eriksson P; Hamsten A
Article: CIRCULATION. 1999;100(7):723-728
Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men
Boquist S; Ruotolo G; Tang R; Björkegren J; Bond MG; de Faire U; Karpe F; Hamsten A
Article: HUMAN MOLECULAR GENETICS. 1999;8(8):1443-1449
A common functional polymorphism (C→A substitution at position-863) in the promoter region of the tumour necrosis factor-α (TNF-α) gene associated with reduced circulating levels of TNF-α
Skoog T; van't Hooft FM; Kallin B; Jovinge S; Boquist S; Nilsson J; Eriksson P; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1999;19(6):1577-1581
Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells
Nilsson L; Takemura T; Eriksson P; Hamsten A
Article: BLOOD. 1999;93(10):3432-3441
Two common functional polymorphisms in the promoter region of the coagulation factor VII gene determining plasma factor VII activity and mass concentration
van't Hooft FM; Silveira A; Tornvall P; Iliadou A; Ehrenborg E; Eriksson P; Hamsten A
Article: CIRCULATION RESEARCH. 1999;84(9):1085-1094
Very low-density lipoprotein activates nuclear factor-κB in endothelial cells
Dichtl W; Nilsson L; Goncalves I; Ares MPS; Banfi C; Calara F; Hamsten A; Eriksson P; Nilsson J
Article: JOURNAL OF LIPID RESEARCH. 1999;40(5):913-919
VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression:: involvement of the VLDL receptor
Nilsson L; Gåfvels M; Musakka L; Ensler K; Strickland DK; Angelin B; Hamsten A; Eriksson P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1999;19(5):1354-1360
Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells
Allison BA; Nilsson L; Karpe F; Hamsten A; Eriksson P
Article: CIRCULATION. 1999;99(14):1788-1794
Functional polymorphism in the regulatory region of gelatinase B gene in relation to severity of coronary atherosclerosis
Zhang BP; Ye S; Herrmann SM; Eriksson P; de Maat M; Evans A; Arveiler D; Luc G; Cambien F; Hamsten A; Watkins H; Henney AM
Article: THROMBOSIS AND HAEMOSTASIS. 1999;81(4):538-542
Haemostatic, endothelial and lipoprotein parameters and blood pressure levels in women with a history of preeclampsia
He S; Silveira A; Hamsten A; Blombäck M; Bremme K
Article: ATHEROSCLEROSIS. 1999;143(2):377-381
C4 null alleles and myocardial infarction
Nityanand S; Hamsten A; Lithell H; Holm G; Lefvert AK
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 1999;48(3):301-307
Differences in postprandial concentrations of very-low-density lipoprotein and chylomicron remnants between normotriglyceridemic and hypertriglyceridemic men with and without coronary heart disease
Karpe F; Hellénius ML; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1999;19(3):485-492
Socioeconomic status and determinants of hemostatic function in healthy women
Wamala SP; Murray MA; Horsten M; Eriksson M; Schenck-Gustafsson K; Hamsten A; Silveira A; Orth-Gomér K
Article: ATHEROSCLEROSIS. 1998;141(2):307-314
Magnitude of alimentary lipemia is related to intima-media thickness of the common carotid artery in middle-aged men
Karpe F; de Faire U; Mercuri M; Bond MG; Hellenius ML; Hamsten A
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998;32(6):1648-1656
Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT)
Ruotolo G; Ericsson CG; Tettamanti C; Karpe F; Grip L; Svane B; Nilsson J; De Faire U; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1998;18(11):1679-1685
Unsaturated fatty acids increase plasminogen activator inhibitor-1 expression in endothelial cells
Nilsson L; Banfi C; Diczfalusy U; Tremoli E; Hamsten A; Eriksson P
Article: THROMBOSIS AND HAEMOSTASIS. 1998;80(2):220-224
Coagulation factor V (Arg⁵⁰⁶→Gln) mutation and early saphenous vein graft occlusion after coronary artery bypass grafting
Moor E; Silveira A; van't Hooft F; Tornvall P; Blombäck M; Wiman B; Rydén L; Hamsten A
Article: CARDIOLOGY. 1998;90(1):8-12
Diastolic and systolic function as predictors of exercise capacity after myocardial infarction in young men
Eriksson SV; Caidahl K; de Faire U; Lindvall K; Rehnqvist N; Hamsten A
Article: JOURNAL OF LIPID RESEARCH. 1998;39(7):1412-1420
Differences in apolipoprotein and lipid composition between human chylomicron remnants and very low density lipoproteins isolated from fasting and postprandial plasma
Björkegren J; Karpe F; Milne RW; Hamsten A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1998;18(5):756-761
A common functional polymorphism in the promoter region of the microsomal triglyceride transfer protein gene influences plasma LDL levels
Karpe F; Lundahl B; Ehrenborg E; Eriksson P; Hamsten A
Article: ATHEROSCLEROSIS. 1998;137(2):391-400
Effects of a cardioselective β-blocker on postprandial triglyceride-rich lipoproteins, low density lipoprotein particle size and glucose-insulin homeostasis in middle-aged men with modestly increased cardiovascular risk
Boquist S; Ruotolo G; Hellénius ML; Danell-Toverud K; Karpe F; Hamsten A
Article: CIRCULATION. 1998;97(8):780-785
Effects of recombinant apolipoprotein A-I_Milano on aortic atherosclerosis in apolipoprotein E-deficient mice
Shah PK; Nilsson J; Kaul S; Fishbein MC; Ageland H; Hamsten A; Johansson J; Karpe F; Cercek B
Article: ATHEROSCLEROSIS. 1998;137(1):107-113
Alimentary lipemia enhances the membrane expression of platelet P-selectin without affecting other markers of platelet activation
Bröijersén A; Karpe F; Hamsten A; Goodall AH; Hjemdahl P
Article: EUROPEAN HEART JOURNAL. 1998;19(3):402-410
Progression of coronary artery disease in young male post-infarction patients is linked to disturbances of carbohydrate and lipoprotein metabolism and to impaired fibrinolytic function
Bavenholm P; de Faire U; Landou C; Efendic S; Nilsson J; Wiman B; Hamsten A
Article: JOURNAL OF INTERNAL MEDICINE. 1998;243(2):109-113
Helicobacter pylori seropositivity is not associated with inflammatory parameters, lipid concentrations and degree of coronary artery disease
Regnström J; Jovinge S; Båvenholm P; Ericsson CG; De Faire U; Hamsten A; Hellenius ML; Nilsson J; Tornvall P
Article: JOURNAL OF LIPID RESEARCH. 1998;39(2):423-436
Transient triglyceridemia in healthy normolipidemic men increases cellular processing of large very low density lipoproteins by fibroblasts in vitro
Björkegren J; Karpe F; Vitols S; Tornvall P; Hamsten A
Article: THROMBOSIS AND HAEMOSTASIS. 1998;79(2):268-275
Platelet activity in vivo in hyperlipoproteinemia -: Importance of combined hyperlipidemia
Bröijersén A; Hamsten A; Eriksson M; Angelin B; Hjemdahl P
Article: DIABETOLOGIA. 1998;41(1):65-71
Adipose tissue secretion of plasminogen activator inhibitor-1 in non-obese and obese individuals
Eriksson P; Reynisdottir S; Lönnqvist F; Stemme V; Hamsten A; Arner P
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1998;18(1):20-26
Very-low-density lipoprotein response element in the promoter region of the human plasminogen activator inhibitor-1 gene implicated in the impaired fibrinolysis of hypertriglyceridemia
Eriksson P; Nilsson L; Karpe F; Hamsten A
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 1998;47(1):113-118
Evidence for a role of tumor necrosis factor α in disturbances of triglyceride and glucose metabolism predisposing to coronary heart disease
Jovinge S; Hamsten A; Tornvall P; Proudler A; Båvenholm P; Ericsson CG; Godsland I; de Faire U; Nilsson J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 1997;80(9):1125-1129
Effect of bezafibrate treatment over five years on coronary plaques causing 20% to 50% diameter narrowing (The Bezafibrate Coronary Atherosclerosis Intervention Trial [BECAIT])
Ericsson CG; Nilsson J; Grip L; Svane B; Hamsten A
Article: JOURNAL OF LIPID RESEARCH. 1997;38(5):949-961
Chylomicron chylomicron remnant turnover in humans: evidence for margination of chylomicrons and poor conversion of larger to smaller chylomicron remnants
Karpe F; Olivecrona T; Hamsten A; Hultin M
Article: CARDIOVASCULAR RESEARCH (CVR). 1997;34(1):248-253
Mortality prediction in diabetic patients with myocardial infarction: Experiences from the DIGAMI study
Malmberg K; Ryden L; Hamsten A; Herlitz J; Waldenstrom A; Wedel H
Article: JOURNAL OF LIPID RESEARCH. 1997;38(2):301-314
Alterations of VLDL composition during alimentary lipemia
Bjorkegren J; Hamsten A; Milne RW; Karpe F
Article: EUROPEAN HEART JOURNAL. 1996;17:37-42
Secondary preventive potential of lipid-lowering drugs - The Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT)
deFaire U; Ericsson CG; Grip L; Nilsson J; Svane B; Hamsten A
Article: DIABETES CARE. 1996;19(11):1200-1206
The antidiabetogenic effect of GLP-1 is maintained during a 7-day treatment period and improves diabetic dyslipoproteinemia in NIDDM patients
JunttiBerggren L; Pigon J; Karpe F; Hamsten A; Gutniak M; Vignati L; Efendic S
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1996;16(11):1333-1339
In vivo demonstration in humans that large postprandial triglyceride-rich lipoproteins activate coagulation factor VII through the intrinsic coagulation pathway
Silveira A; Karpe F; Johnsson H; Bauer KA; Hamsten A
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 1996;45(11):1375-1382
High-density lipoprotein: Relations to metabolic parameters and severity of coronary artery disease
Tornvall P; Karpe F; Proudler A; Bavenholm P; Landou C; Olivecrona T; Hamsten A
Article: THROMBOSIS AND HAEMOSTASIS. 1996;76(4):535-540
Proneness to formation of tight and rigid fibrin gel structures in men with myocardial infarction at a young age
Fatah K; Silveira A; Tornvall P; Karpe F; Blomback M; Hamsten A
Article: EUROPEAN HEART JOURNAL. 1996;17(9):1337-1344
Effects of insulin treatment on cause-specific one-year mortality and morbidity in diabetic patients with acute myocardial infarction
Malmberg K; Ryden L; Hamsten A; Herlitz J; Waldenstrom A; Wedel H
Article: THROMBOSIS AND HAEMOSTASIS. 1996;76(2):171-176
Gemfibrozil reduces thrombin generation in patients with combined hyperlipidaemia, without influencing plasma fibrinogen, fibrin gel structure or coagulation factor VII
Broijersen A; Hamsten A; Silveira A; Fatah K; Goodall AH; Eriksson M; Angelin B; Hjemdahl P
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1996;271(22):13055-13060
Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression
Ye S; Eriksson P; Hamsten A; Kurkinen M; Humphries SE; Henney AM
Article: THE LANCET. 1996;347(9005):849-853
Angiographic assessment of effects of bezafibrate on progression of coronary artery disease in young male postinfarction patients
Ericsson CG; Hamsten A; Nilsson J; Grip L; Svane B; deFaire U
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 1996;63(3):377-385
Inverse relation between the concentration of low-density lipoprotein Vitamin E and severity of coronary artery disease
Regnstrom J; Nilsson J; Moldeus P; Strom K; Bavenholm P; Tornvall P; Hamsten A
Article: JOURNAL OF LIPID RESEARCH. 1996;37(1):76-86
Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway
Bjorkegren J; Packard CJ; Hamsten A; Bedford D; Caslake M; Foster L; Shepherd J; Stewart P; Karpe F
Article: FREE RADICAL RESEARCH. 1995;23(6):581-592
THE SUSCEPTIBILITY OF LOW-DENSITY-LIPOPROTEIN TO CHEMICAL OXIDATION IS CLOSELY-RELATED TO PRONENESS TO BIOLOGICAL MODIFICATION
FROSTEGARD J; REGNSTROM J; TORNVALL P; HAMSTEN A; NILSSON J
Article: METABOLISM: CLINICAL AND EXPERIMENTAL. 1995;44(11):1481-1488
ASSOCIATION OF INSULIN AND INSULIN PROPEPTIDES WITH AN ATHEROGENIC LIPOPROTEIN PHENOTYPE
BAVENHOLM P; KARPE F; PROUDLER A; TORNVALL P; CROOK D; HAMSTEN A
Article: JOURNAL OF LIPID RESEARCH. 1995;36(10):2104-2112
INTERACTION OF THE LIPOPROTEIN-LIPASE ASPARAGINE-291-]SERINE MUTATION WITH BODY-MASS INDEX DETERMINES ELEVATED PLASMA TRIACYLGLYCEROL CONCENTRATIONS - A STUDY IN HYPERLIPIDEMIC SUBJECTS, MYOCARDIAL-INFARCTION SURVIVORS, AND HEALTHY-ADULTS
FISHER RM; MAILLY F; PEACOCK RE; HAMSTEN A; SEED M; YUDKIN JS; BEISIEGEL U; FEUSSNER G; MILLER G; HUMPHRIES SE; TALMUD PJ
Article: CIRCULATION. 1995;92(6):1422-1429
INSULIN, INTACT AND SPLIT PROINSULIN, AND CORONARY-ARTERY DISEASE IN YOUNG MEN
BAVENHOLM P; PROUDLER A; TORNVALL P; GODSLAND I; LANDOU C; DEFAIRE U; HAMSTEN A
Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1995;25(9):699-707
CELLULAR PROCESSING OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS FROM YOUNG POSTINFARCTION PATIENTS AND HEALTHY CONTROLS
TORNVALL P; REGNSTROM J; HAMSTEN A
Article: HEART. 1995;74(2):124-130
LONG-TERM PROGNOSTIC-SIGNIFICANCE OF M-MODE ECHOCARDIOGRAPHY IN YOUNG MEN AFTER MYOCARDIAL-INFARCTION
ERIKSSON SV; CAIDAHL K; HAMSTEN A; DEFAIRE U; REHNQVIST N; LINDVALL K
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1995;15(8):1086-1093
LIPOPROTEIN-LIPASE MASS AND ACTIVITY IN PLASMA AND THEIR INCREASE AFTER HEPARIN ARE SEPARATE PARAMETERS WITH DIFFERENT RELATIONS TO PLASMA-LIPOPROTEINS
TORNVALL P; OLIVECRONA G; KARPE F; HAMSTEN A; OLIVECRONA T
Article: ATHEROSCLEROSIS. 1995;116(1):135-145
COMMON VARIATION IN THE GENE FOR APOLIPOPROTEIN-B MODULATES POSTPRANDIAL LIPOPROTEIN METABOLISM - A HYPOTHESIS GENERATING STUDY
PEACOCK RE; KARPE F; TALMUD PJ; HAMSTEN A; HUMPHRIES SE
Article: CURRENT OPINION IN LIPIDOLOGY. 1995;6(3):123-129
POSTPRANDIAL LIPOPROTEIN METABOLISM AND ATHEROSCLEROSIS
KARPE F; HAMSTEN A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1995;15(5):665-668
ASSOCIATION BETWEEN CIRCULATING IMMUNE-COMPLEXES, COMPLEMENT C4 NULL ALLELES, AND MYOCARDIAL-INFARCTION BEFORE AGE 45 YEARS
LEFVERT AK; HAMSTEN A; HOLM G
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1995;15(5):655-664
COAGULATION-FACTOR-VII MASS AND ACTIVITY IN YOUNG MEN WITH MYOCARDIAL-INFARCTION AT A YOUNG AGE - ROLE OF PLASMA-LIPOPROTEINS AND FACTOR-VII GENOTYPE
MOOR E; SILVEIRA A; VANTHOOFT F; SUONTAKA AM; ERIKSSON P; BLOMBACK M; HAMSTEN A
Article: THROMBOSIS AND HAEMOSTASIS. 1995;73(4):568-575
RELATIONSHIPS OF INSULIN AND INTACT AND SPLIT PROINSULIN TO HEMOSTATIC FUNCTION IN YOUNG MEN WITH AND WITHOUT CORONARY-ARTERY DISEASE
BAVENHOLM P; PROUDLER A; SILVEIRA A; CROOK D; BLOMBACK M; DEFAIRE U; HAMSTEN A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1995;15(4):468-478
A common variant in the gene for lipoprotein lipase (Asp9-->Asn). Functional implications and prevalence in normal and hyperlipidemic subjects.
Mailly F; Tugrul Y; Reymer PW; Bruin T; Seed M; Groenemeyer BF; Asplund-Carlson A; Vallance D; Winder AF; Miller GJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1995;92(6):1851-1855
ALLELE-SPECIFIC INCREASE IN BASAL TRANSCRIPTION OF THE PLASMINOGEN-ACTIVATOR INHIBITOR-1 GENE IS ASSOCIATED WITH MYOCARDIAL-INFARCTION
ERIKSSON P; KALLIN B; VANTHOOFT FM; BAVENHOLM P; HAMSTEN A
Article: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 1995;15(2):199-207
QUANTIFICATION OF POSTPRANDIAL TRIGLYCERIDE-RICH LIPOPROTEINS IN HEALTHY-MEN BY RETINYL ESTER LABELING AND SIMULTANEOUS MEASUREMENT OF APOLIPOPROTEINS B-48 AND B-100
KARPE F; BELL M; BJORKEGREN J; HAMSTEN A
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Corrigendum: NATURE COMMUNICATIONS. 2021;12(1):995
Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability (vol 12, 24, 2021)
Lagou V; Magi R; Hottenga J-J; Grallert H; Perry JRB; Bouatia-Naji N; Marullo L; Rybin D; Jansen R; Min JL; Dimas AS; Ulrich A; Zudina L; Gadin JR; Jiang L; Faggian A; Bonnefond A; Fadista J; Stathopoulou MG; Isaacs A; Willems SM; Navarro P; Tanaka T; Jackson AU; Montasser ME; O'Connell JR; Bielak LF; Webster RJ; Saxena R; Stafford JM; St Pourcain B; Timpson NJ; Salo P; Shin S-Y; Amin N; Smith AV; Li G; Verweij N; Goel A; Ford I; Johnson PCD; Johnson T; Kapur K; Thorleifsson G; Strawbridge RJ; Rasmussen-Torvik LJ; Esko T; Mihailov E; Fall T; Fraser RM; Mahajan A; Kanoni S; Giedraitis V; Kleber ME; Silbernagel G; Meyer J; Mueller-Nurasyid M; Ganna A; Sarin A-P; Yengo L; Shungin D; Luan J; Horikoshi M; An P; Sanna S; Boettcher Y; Rayner NW; Nolte IM; Zemunik T; van Iperen E; Kovacs P; Hastie ND; Wild SH; McLachlan S; Campbell S; Polasek O; Carlson O; Egan J; Kiess W; Willemsen G; Kuusisto J; Laakso M; Dimitriou M; Hicks AA; Rauramaa R; Bandinelli S; Thorand B; Liu Y; Miljkovic I; Lind L; Doney A; Perola M; Hingorani A; Kivimaki M; Kumari M; Bennett AJ; Groves CJ; Herder C; Koistinen HA; Kinnunen L; de Faire U; Bakker SJL; Uusitupa M; Palmer CNA; Jukema JW; Sattar N; Pouta A; Snieder H; Boerwinkle E; Pankow JS; Magnusson PK; Krus U; Scapoli C; de Geus EJCN; Blueher M; Wolffenbuttel BHR; Province MA; Abecasis GR; Meigs JB; Hovingh GK; Lindstroem J; Wilson JF; Wright AF; Dedoussis GV; Bornstein SR; Schwarz PEH; Toenjes A; Winkelmann BR; Boehm BO; Maerz W; Metspalu A; Price JF; Deloukas P; Koerner A; Lakka TA; Keinanen-Kiukaanniemi SM; Saaristo TE; Bergman RN; Tuomilehto J; Wareham NJ; Langenberg C; Mannisto S; Franks PW; Hayward C; Vitart V; Kaprio J; Visvikis-Siest S; Balkau B; Altshuler D; Rudan I; Stumvoll M; Campbell H; van Duijn CM; Gieger C; Illig T; Ferrucci L; Pedersen NL; Pramstaller PP; Boehnke M; Frayling TM; Shuldiner AR; Peyser PA; Kardia SLR; Palmer LJ; Penninx BW; Meneton P; Harris TB; Navis G; van der Harst P; Smith GD; Forouhi NG; Loos RJF; Salomaa V; Soranzo N; Boomsma DI; Groop L; Tuomi T; Hofman A; Munroe PB; Gudnason V; Siscovick DS; Watkins H; Lecoeur C; Vollenweider P; Franco-Cereceda A; Eriksson P; Jarvelin M-R; Stefansson K; Hamsten A; Nicholson G; Karpe F; Dermitzakis ET; Lindgren CM; McCarthy MI; Froguel P; Kaakinen MA; Lyssenko V; Watanabe RM; Ingelsson E; Florez JC; Dupuis J; Barroso I; Morris AP; Prokopenko I
Corrigendum: NATURE GENETICS. 2018;50(12):1755
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits (vol 50, pg 1412, 2018)
Evangelou E; Warren HR; Mosen-Ansorena D; Mifsud B; Pazoki R; Gao H; Ntritsos G; Dimou N; Cabrera CP; Karaman I; Fu LN; Evangelou M; Witkowska K; Tzanis E; Hellwege JN; Giri A; Edwards DRV; Sun YV; Cho K; Gaziano JM; Wilson PWF; Tsao PS; Kovesdy CP; Esko T; Magi R; Milani L; Almgren P; Boutin T; Debette S; Ding J; Giulianini F; Holliday EG; Jackson AU; Li-Gao R; Lin W-Y; Luan J; Mangino M; Oldmeadow C; Prins BP; Qian Y; Sargurupremraj M; Shah N; Surendran P; Theriault S; Verweij N; Willems SM; Zhao J-H; Amouyel P; Connell J; de Mutsert R; Doney ASF; Farrall M; Menni C; Morris AD; Noordam R; Pare G; Poulter NR; Shields DC; Stanton A; Thom S; Abecasis G; Amin N; Arking DE; Ayers KL; Barbieri CM; Batini C; Bis JC; Blake T; Bochud M; Boehnke M; Boerwinkle E; Boomsma DI; Bottinger EP; Braund PS; Brumat M; Campbell A; Campbell H; Chakravarti A; Chambers JC; Chauhan G; Ciullo M; Cocca M; Collins F; Cordell HJ; Davies G; de Borst MH; de Geus EJ; Deary IJ; Deelen J; Del Greco FM; Demirkale CY; Dorr M; Ehret GB; Elosua R; Enroth S; Erzurumluoglu AM; Ferreira T; Franberg M; Franco OH; Gandin I; Gasparini P; Giedraitis V; Gieger C; Girotto G; Goel A; Gow AJ; Gudnason V; Guo X; Gyllensten U; Hamsten A; Harris TB; Harris SE; Hartman CA; Havulinna AS; Hicks AA; Hofer E; Hofman A; Hottenga J-J; Huffman JE; Hwang S-J; Ingelsson E; James A; Jansen R; Jarvelin M-R; Joehanes R; Johansson A; Johnson AD; Joshi PK; Jousilahti P; Jukema JW; Jula A; Kahonen M; Kathiresan S; Keavney BD; Khaw K-T; Knekt P; Knight J; Kolcic I; Kooner JS; Koskinen S; Kristiansson K; Kutalik Z; Laan M; Larson M; Launer LJ; Lehne B; Lehtimaki T; Liewald DCM; Lin L; Lind L; Lindgren CM; Liu Y; Loos RJF; Lopez LM; Lu Y; Lyytikainen L-P; Mahajan A; Mamasoula C; Marrugat J; Marten J; Milaneschi Y; Morgan A; Morris AP; Morrison AC; Munson PJ; Nalls MA; Nandakumar P; Nelson CP; Niiranen T; Nolte IM; Nutile T; Oldehinkel AJ; Oostra BA; O'Reilly PF; Org E; Padmanabhan S; Palmas W; Palotie A; Pattie A; Penninx BWJH; Perola M; Peters A; Polasek O; Pramstaller PP; Quang TN; Raitakari OT; Ren M; Rettig R; Rice K; Ridker PM; Ried JS; Riese H; Ripatti S; Robino A; Rose LM; Rotter JI; Rudan I; Ruggiero D; Saba Y; Sala CF; Salomaa V; Samani NJ; Sarin A-P; Schmidt R; Schmidt H; Shrine N; Siscovick D; Smith AV; Snieder H; Sober S; Sorice R; Starr JM; Stott DJ; Strachan DP; Strawbridge RJ; Sundstrom J; Swertz MA; Taylor KD; Teumer A; Tobin MD; Tomaszewski M; Toniolo D; Traglia M; Trompet S; Tuomilehto J; Tzourio C; Uitterlinden AG; Vaez A; van der Most PJ; van Duijn CM; Vergnaud A-C; Verwoert GC; Vitart V; Volker U; Vollenweider P; Vuckovic D; Watkins H; Wild SH; Willemsen G; Wilson JF; Wright AF; Yao J; Zemunik T; Zhang W; Attia JR; Butterworth AS; Chasman DI; Conen D; Cucca F; Danesh J; Hayward C; Howson JMM; Laakso M; Lakatta EG; Langenberg C; Melander O; Mook-Kanamori DO; Palmer CNA; Risch L; Scott RA; Scott RJ; Sever P; Spector TD; van der Harst P; Wareham NJ; Zeggini E; Levy D; Munroe PB; Newton-Cheh C; Brown MJ; Metspalu A; Hung AM; O'Donnell CJ; Edwards TL; Psaty BM; Tzoulaki I; Barnes MR; Wain LV; Elliott P; Caulfield MJ
Corrigendum: NATURE GENETICS. 2018;50(12):1752
Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps (vol 48, pg 1303, 2016)
Iotchkova V; Huang J; Morris JA; Jain D; Barbieri C; Walter K; Min JL; Chen L; Astle W; Cocca M; Deelen P; Elding H; Farmaki A-E; Franklin CS; Franberg M; Gaunt TR; Hofman A; Jiang T; Kleber ME; Lachance G; Luan J; Malerba G; Matchan A; Mead D; Memari Y; Ntalla I; Panoutsopoulou K; Pazoki R; Perry JRB; Rivadeneira F; Sabater-Lleal M; Sennblad B; Shin S-Y; Southam L; Traglia M; van Dijk F; van Leeuwen EM; Zaza G; Zhang W; Amin N; Butterworth A; Chambers JC; Dedoussis G; Dehghan A; Franco OH; Franke L; Frontini M; Gambaro G; Gasparini P; Hamsten A; Isaacs A; Kooner JS; Kooperberg C; Langenberg C; Marz W; Scott RA; Swertz MA; Toniolo D; Uitterlinden AG; van Duijn CM; Watkins H; Zeggini E; Maurano MT; Timpson NJ; Reiner AP; Auer PL; Soranzo N
Editorial comment: CIRCULATION. 2012;126(15):1815-1817
Quest for Genes and Mechanisms Linking the Human Chromosome 9p21.3 Locus to Cardiovascular Disease
Hamsten A; Eriksson P
Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2011;70:A16
HLA-DRB1*04 IS A NOVEL FETAL SUSCEPTIBILITY ALLELE IN CONGENITAL HEART BLOCK
Ostberg T; Gorgen S; Salomonsson S; Ding B; Eliasson H; Elfving A; Malarstig A; Alfredsson L; Klareskog L; Hamsten A; Olsson T; Padukov L; Axelsson T; Gadler F; Jonzon A; Sonesson SE; Kockum I; Wahren-Herlenius M
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):12
TELOMERES ARE SHORTER IN PATIENTS WITH POLYGENIC AND MONOGENIC FORMS OF CORONARY HEART DISEASE
Maubaret CG; Salpea KD; Jain A; Cooper JA; Hamsten A; Sanders J; Montgomery H; Neil A; Nair D; Humphries SE
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):178
ECHOCARDIOGRAPHIC VISUAL VERSUS COMPUTERIZED EVALUATION OF THE DEGREE OF AORTIC VALVE CALCIFICATION IN PATIENTS WITH AORTIC VALVE AND ROOT PATHOLOGY
Yousry M; Eriksson MJ; Rickenlund A; Petrini J; Gustavsson T; Eriksson P; Hamsten A; Franco-Cereceda A; Liska J; Caidahl K
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2010;11(2):13
COMMON GENETIC VARIANTS ASSOCIATED WITH LOW Lp(a) KRINGLE-IV COPY NUMBER, HIGH Lp(a) CONCENTRATION, AND INCREASED RISK OF CORONARY HEART DISEASE
Seedorf U; Peden J; Hopewell J; Kyriakou T; Goel A; Heath S; Parish S; Barlera S; Grazia M; Rust S; Bennett D; Silveira A; Malarstig A; Green F; Lathrop M; Gigante B; Leander K; de Faire U; Clarke R; Hamsten A; Collins R; Watkins H
Meeting abstract: ATHEROSCLEROSIS. 2009;207(1):E4
ASSOCIATION STUDY OF CORONARY ARTERY DISEASE (CAD) USING HUMANCVD 50K CHIP
Goel A; Clarke R; Hopewell JC; Kyriakou T; Heath SC; Parish S; Barlera S; Franzosi MG; Rust S; Bennett D; Silveira A; Malarstig A; Green FR; Lathrop M; Gigante B; Leander K; Faire U; Seedorf U; Hamsten A; Collins R; Watkins H; Farrall M; Peden JF
Letter: NATURE GENETICS. 2008;40(12):1387-1388
Lack of support for association between common variation in TNFSF4 and myocardial infarction in a German population Reply
Wang X; Ria M; Eriksson P; de Faire U; Hamsten A; Paigen B
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):213
CAROTID INTIMA MEDIA THICKNESS AS MARKER OF ATHEROSCLEROSIS: RESULTIS OF THE IMPROVE STUDY
Tremoli E; Baldassarre D; Paoletti R; Rauramaa R; Nyssonen K; De Faire U; Hamsten A; Humphries S; Smit A; Mannarino E; Gyral P; Grossi E
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):116
Endothelial activity is related to diet and components of the metabolic syndrome, but not to advanced glycation end-products in healthy swedish men
Sjogren P; Basta G; de Caterina R; Rosell M; Basu S; Silveira A; de Faire U; Vessby B; Hamsten A; Hellenius ML; Fisher RM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):213
Activation of the peroxisome proliferator-activated receptor delta increases the expression of the human apolipoprotein A-II gene
Thulin P; Hamsten A; Ehrenborg E
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):60-61
Human evidence for the involvement of INSIG-2 in the adipose tissue metabolism
Krapivner S; Popov S; Chemogubova E; Hellenius M-L; Fisher R; Hamsten A; van't Hooft F
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):5
Alternative splicing of human peroxisome proliferator-activated receptor delta: Effects on translation efficiency and trans-activation ability
Lundell K; Thulin P; Hamsten A; Ehrenborg E
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2007;8(1):3
Stearoyl coa desaturase (SCD) activity in human adipose tissue is increased in the metabolic syndrome
Fisher RM; Sjogren P; Rose M; Hamsten A; Vessby B; Hellenius M-L
Editorial comment: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2006;26(11):2419-2420
Fibrin gel architecture influences endogenous fibrinolysis and may promote coronary artery disease
Silveira A; Hamsten A
Corrigendum: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. 2006;194(5):1499
Sex hormone-binding globulin - A surrogate marker for the prothrombic effects of combined oral contraceptives (vol 190, pg 332, 2004)
van Roolien M; Silveira A; Hamsten A; Bremme K
Letter: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2006;26(4):E31-E32
Oxidized LDL and the metabolic syndrome - In response
Sjogren P; Hamsten A; Hellenius ML; Fisher RM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):149-150
Quest for genes predisposing to atherothrombosis
Hamsten A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):231
Relationships between autoantibodies against modified LDL and advanced glycation end-products in clinically healthy men
Sjögren P; Fredrikson GN; Basta G; Hamsten A; Nilsson J; Hellenius ML; De Caterina R; Fisher RM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):200-201
Atherosclerosis before and after transformation of fatty streaks into plaques -: Implications for disease expansion and gene expression
Kovacs A; Skogsberg J; Nilsson R; Kohler M; Lundstrom J; Kurtsdotter I; Brinne B; Hamsten A; Tegner J; Bjorkegren J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):316
Matrix metalloproteinase-1 gene haplotype influences risk of myocardial infarction
Pearce E; Tregouet D; Samnergard A; Morgan A; Cox C; Hamsten A; Eriksson P; Ye S
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):145
A new OX40L promoter haplotype showing association with coronary artery disease in the PROCARDIS trio family and SCARF cohorts
Ria M; Olsson PG; Bengtsson O; Eriksson P; Hamsten A; Lagercrantz J
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):505
DGAT1 mediates the effect of the MODY1 gene HNF4A on hepatic secretion of triglyceride-rich lipoproteins
Krapivner S; Silveira A; Hamsten A; Van'T Hooft FM
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):492
Influence of INSIG-1 and INSIG-2 silencing on the expression of genes involved in fatty acid and cholesterol metabolism in HUH7 human hepatoma cells
Chernogubova E; Krapivner S; Hamsten A; Van'T Hooft F
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):357
The Stockholm atherosclerosis gene expression (stage) study -: Multiorgan expression profiling in well-characterized coronary artery disease patients
Hägg S; Lundström J; Skogsberg J; Nilsson R; Hallén K; Noori P; Ivert T; Hamsten A; Tegnér J; Björkegren J
Editorial comment: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2005;25(6):1100-1101
Quest for genes regulating plasma fibrinogen concentration - Still a long way to go
Hamsten A; Mannila MN; Silveira A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):78
Insight into the nature of the URF-uukunary event association using mendelian randomisation
Shah T; Casas J; Cooper J; Hawe E; Stephens J; Yudkin J; Colhoun H; Bautista L; Meade T; Gaffney D; McMahon A; Hamsten A; Sattar N; Humphries S; Hingorani A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):94-95
Genotype-specific increase in plasma concentrations of activated coagulation factor VII in response to experimental inflammation. A link between infection and acute myocardial infarction
Tornvall P; Held C; Ericsson CG; Silveira A; Hamsten A; Bennermo M
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2005;6(1):92
The fibrinogen gene loci revisited
Hamsten A; Mannila MN; Eriksson P; Silveira A
Published conference paper: JOURNAL OF NUTRITION. 2004;134(7):1729-1735
Milk-derived fatty acids are associated with a more favorable LDL particle size distribution in healthy men
Sjogren P; Rosell M; Skoglund-Andersson C; Zdravkovic S; Vessby B; de Faire U; Hamsten A; Hellenius ML; Fisher RM
Editorial comment: THE LANCET. 2004;363(9426):2011-2012
Statins in rheumatoid arthritis - two birds with one stone?
Klareskog L; Hamsten A
Published conference paper: BRITISH JOURNAL OF SURGERY. 2004;91(1):86-89
Genetic approach to the role of cysteine proteases in the expansion of abdominal aortic aneurysms
Eriksson P; Jones KG; Brown LC; Greenhalgh RM; Hamsten A; Powell JT
Meeting abstract: EUROPEAN HEART JOURNAL. 2003;24:156
Expression of Toll-like receptors in human atherosclerotic lesions and the relevance to myocardial infarction
Edfeldt K; Bennet AM; Eriksson P; Hamsten A; Hansson GK; DeFaire U; Yan ZQ
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):232
Evidence that the low density lipoprotein receptor prevents secretion of dense apoB100-containing lipoproteins from the liver
Bjorkegren J; Larsson S; Hamsten A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):10
DAIS: New results and links between correcting lipid abnormalities and cardiovascular benefits
Taskinen MR; Vakkilainen J; Ansquer JC; Aubin F; Hamsten A; Steiner G
Editorial comment: ARTERIOSCLEROSIS, THROMBOSIS, AND VASCULAR BIOLOGY. 2003;23(1):6-7
Thrombospondins and premature coronary artery disease - Time to go beyond genotype-phenotype association studies
Hamsten A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):323
Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease
Eriksson P; Deguchi H; Samnegard A; Lundman P; Boquist S; Tornvall P; Ericsson CG; Bergstrand L; Hansson LO; Hamsten A
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):219
Peroxisome proliferator activated receptor genotypes in relation to cardiovascular risk factors and risk of coronary heart disease in hypercholesterolaemic men
Skogsberg J; McMahon AD; Karpe F; Hamsten A; Packard CJ; Ehrenborg E
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):219
Effects of diet and exercise on the regulation of PPARα, δ and γ expression in rat skeletal muscle and visceral adipose tissue
Kannisto K; Chibalin A; Zierath JR; Hamsten A; Ehrenborg E
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):48-49
Genetic and structural evaluation of fatty acid transport protein-4 (FATP4) in relation to markers of the insulin resistance syndrome
Gertow K; Bellanda M; Sunnerhagen M; Eriksson P; Boquist S; Hamsten A; Fisher R
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):31
Characterization of the human homologue to the Ath1 atherosclerosis susceptibility locus in mice
Ria M; Eriksson P; Forsman-Semb K; Olsson PG; Hamsten A; Lagercrantz J
Letter: CIRCULATION. 2002;105(17):E129
On the mechanisms by which human apolipoprotein A-II gene variability relates to hypertriglyceridemia - Response
van't Hooft FM; Ruotolo G; Boquist S; de Faire U; Eggertsen G; Hamsten A
Letter: DIABETOLOGIA. 2001;44(5):654-655
Tumour necrosis factor-α (TNF-α) polymorphisms-857C/A and -863C/A are associated with TNF-α secretion from human adipose tissue
Skoog T; Eriksson P; Hoffstedt J; Rydén M; Hamsten A; Arner P
Published conference paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2000;902:27-37
Genetic diversity in the matrix metalloproteinase family -: Effects on function and disease progression
Henney AM; Ye S; Zhang BP; Jormsjö S; Whatling C; Eriksson P; Hamsten A
Meeting abstract: ATHEROSCLEROSIS. 1999;144:87
Remnants of postprandial triglyceride-rich lipoproteins and atherosclerosis
Karpe F; Boquist S; Larsson A; Hamsten A; Syvänne A
Meeting abstract: ATHEROSCLEROSIS. 1999;144:14-15
Genetic determination of haemostatic risk factors
Hamsten A
Meeting abstract: ATHEROSCLEROSIS. 1999;144:127
Very low density lipoprotein and free fatty acids stimulate nuclear factor-κB activation in endothelial cells
Dichtl W; Nilsson L; Goncalves MI; Ares MPS; Banfi C; Calara F; Hamsten A; Eriksson P; Nilsson J
Meeting abstract: ATHEROSCLEROSIS. 1999;144:112-113
VLDL activation of plasminogen activator inhibitor-1 (PAI-1) expression:: Involvement of the VLDL receptor
Nilsson L; Gåfvels M; Musakka L; Ensler K; Strickland DK; Angelin B; Hamsten A; Eriksson P
Meeting abstract: ATHEROSCLEROSIS. 1999;144:121
A common polymorphism in the promoter region of TNF-alpha gene determining the serum TNF-alpha concentration
Skoog T; van't Hooft FM; Kallin B; Nilsson J; Eriksson P; Hamsten A
Meeting abstract: ATHEROSCLEROSIS. 1999;144:124
Postprandial metabolism and composition of very low density lipoproteins in relation to atherosclerosis
Björkegren J; Hamsten A
Meeting abstract: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 1998;31:390A
Inhibition of aortic atherosclerosis in apolipoprotein E-deficient mice by recombinant apolipoprotein A-I Milano
Shah PK; Nilsson J; Kaul S; Yano J; Zhu J; Hamsten A; Cercek B
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):281
Circulating immune complexes containing food antigens in premature myocardial infarction
Mustafa A; Hamsten A; Lefvert AK
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):188
Platelet function in hypercholesterolemia - importance of combined hyperlipidemia
Broijersen A; Hamsten A; Eriksson M; Angelin B; Hjemdahl P
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):82
Complement factor C3 genotype and risk of MI
Senaratne JWB; Clark LA; Terry CF; Hamsten A; Green FR
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):189
Alpha fibrinogen genotype is associated with the porosity and density of the fibrin gel matrix in MI patients
Curran JM; Fatah K; Blomback M; Humphries S; Hamsten A; Green FR
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):284
Oxidised LDL induced T cell proliferation; LDL from patients with coronary artery disease inhibited the effect of oxidised LDL
Wu RH; Frostegard J; Giscombe R; Hamsten A; Holm G; Nilsson J; Lefvert AK
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):286
Postprandial lipaemia and coronary heart disease
Hamsten A
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):337
Postprandial very low density lipoproteins: Composition and cellular interactions
Bjorkegren J; Karpe F; Tornvall P; Hamsten A
Published conference paper: AMERICAN JOURNAL OF CARDIOLOGY. 1997;80(5A):64E-67E
The way ahead the management of unstable coronary artery disease
Ryden L; Hamsten A
Published conference paper: CARDIOVASCULAR DRUGS AND THERAPY. 1997;11:257-263
Retardation of coronary atherosclerosis: The bezafibrate coronary atherosclerosis intervention trial (BECAIT) and other angiographic trials
DeFaire U; Ericsson CG; Grip L; Nilsson J; Svane B; Hamsten A
Published conference paper: FIBRINOLYSIS. 1997;11:159-162
Bezafibrate following acute myocardial infarction: Important findings from the bezafibrate coronary atherosclerosis intervention trial
Nilsson J; Ericsson CG; Hamsten A; Grip L; Svane B; deFaire U
Corrigendum: CARDIOVASCULAR RESEARCH (CVR). 1997;36(3):460
Mortality prediction in diabetic patients with myocardial infarction:: experiences from the DIGAMI study (vol 34, pg 248, 1997)
Malmberg K; Ryden L; Hamsten A; Herlitz J; Waldenström A; Wedel H
Review: METHODS IN ENZYMOLOGY. 1996;263:95-104
Apolipoprotein B-48
Karpe F; Hamsten A; Uffelman K; Steiner G
Review: BEST PRACTICE AND RESEARCH: CLINICAL HAEMATOLOGY. 1995;8(2):345-363
FIBRINOLYSIS AND ATHEROSCLEROSIS
HAMSTEN A; ERIKSSON P
Editorial comment: NEW ENGLAND JOURNAL OF MEDICINE. 1995;332(10):677-678
HEMOSTATIC FUNCTION AND CORONARY-ARTERY DISEASE
HAMSTEN A
Review: DRUGS UNDER EXPERIMENTAL AND CLINICAL RESEARCH. 1995;21(3):105-124
DESIGN-FEATURES OF A 5-YEAR BEZAFIBRATE CORONARY ATHEROSCLEROSIS INTERVENTION TRIAL (BECAIT)
DEFAIRE U; ERICSSON CG; HAMSTEN A; NILSSON J
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Professor Emeritus/Emerita, Department of Medicine, Karolinska Institutet, 2023-2024

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Docent, Karolinska Institutet, 1990

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