Alexander Sun Zhang

About me

Our research projects focus on germline TP53-mutations (Li-Fraumeni syndrome/hTP53rc). We target research questions with direct clinical relevance in order to directly improve and develop clinical decision making and clinical handling. We study genotype-phenotype relationships using functional analyses, bioinformatical tools and registry based methods.

Journal article: EUROPEAN JOURNAL OF HUMAN GENETICS. 2025;:1-10
Characterisation of heritable TP53-related cancer syndrome in Sweden-a nationwide study of genotype-phenotype correlations in 90 families
Omran M; Liu Y; Sun Zhang A; Poluha A; Stenmark-Askmalm M; Persson F; Hallbeck A-L; Rosen A; Helgadottir HT; Tham E; Bajalica-Lagercrantz S
Article: ESMO OPEN. 2024;9(7):103617
Comprehensive genomic analysis of adrenocortical carcinoma reveals genetic profiles associated with patient survival
Sun-Zhang A; Juhlin CC; Carling T; Scholl U; Schott M; Larsson C; Bajalica-Lagercrantz S
Article: RNA BIOLOGY. 2023;20(1):368-383
Novel compounds that synergize with aminoglycoside G418 or eRF3 degraders for translational readthrough of nonsense mutant TP53 and PTEN
Heldin A; Cancer M; Palomar-Siles M; Ohlin S; Zhang M; Sun-Zhang A; Mariani A; Liu J; Bykov VJN; Wiman KGG
Article: CURRENT GENE THERAPY. 2023;23(5):356-367
Association of MicroRNA-652 Expression with Radiation Response of Colorectal Cancer: A Study from Rectal Cancer Patients in a Swedish Trial of Preoperative Radiotherapy
Pathak S; Meng W-J; Sriramulu S; Jothimani G; Jangamreddy JR; Banerjee A; Ganesan AT; Adell G; Zhang X; Sun-Zhang A; Zhang H; Sun X-F
Article: CANCERS. 2022;14(24):6166
CD163 as a Potential Biomarker in Colorectal Cancer for Tumor Microenvironment and Cancer Prognosis: A Swedish Study from Tissue Microarrays to Big Data Analyses
Ma S; Zhao Y; Liu X; Zhang AS; Zhang H; Hu G; Sun X-F

Review: CANCER BIOLOGY & THERAPY. 2024;25(1):2317999
Understanding the molecular mechanism responsible for developing therapeutic radiation-induced radioresistance of rectal cancer and improving the clinical outcomes of radiotherapy - A review
Jain SM; Ravichandran SN; Kumar MM; Banerjee A; Sun-Zhang A; Zhang H; Pathak R; Sun X-F; Pathak S
Review: CANCER INVESTIGATION. 2024;42(2):119-140
A Review on Emerging Techniques for Diagnosis of Colorectal Cancer
Ravichandran SN; Das D; Dayananda EK; Dey A; Banerjee A; Sun-Zhang A; Zhang H; Sun X-F; Pathak S
Review: CURRENT CANCER DRUG TARGETS. 2024;24(6):595-611
An Updated Review on Molecular Biomarkers in Diagnosis and Therapy of Colorectal Cancer
Ravichandran SN; Murali Kumar M; Das A; Banerjee A; Veronica S; Sun-Zhang A; Zhang H; Anbalagan M; Sun X-F; Pathak S
Review: CLINICAL & TRANSLATIONAL ONCOLOGY. 2023;25(12):3345-3356
A concise review on miRNAs as regulators of colon cancer stem cells and associated signalling pathways
Banerjee A; Deka D; Muralikumar M; Sun-Zhang A; Bisgin A; Christopher C; Zhang H; Sun X-F; Pathak S
Review: TECHNOLOGY IN CANCER RESEARCH & TREATMENT. 2023;22:15330338231178403
Recent Advancements, Limitations, and Future Perspectives of the use of Personalized Medicine in Treatment of Colon Cancer
Dey A; Mitra A; Pathak S; Prasad S; Zhang AS; Zhang H; Sun X-F; Banerjee A