Alex Bersellini Farinotti

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About me

Research Specialist in the Molecular Pain Group.

After defending my PhD project, which focused on the antibody activation of sensory neurons, I stayed in Camilla Svensson's group to work as a post-doc and now as a research specialist on exploring new drug delivery methodologies for the treatment of chronic pain.

Education:
- Research Specialist (2022 - today) at Karolinska Institutet, Stockholm, Sweden
- Post-doc (2020-2022) at Karolinska Institutet, Stockholm, Sweden

- Ph.D. Degree (2014-2019) at Karolinska Institutet, Stockholm, Sweden

- Master's Degree in Molecular Biology (2012-2013) at University of Parma, Parma, Italy

- Bachelor's Degree in Biology (2008-2011) at University of Parma, Parma, Italy

Articles

Journal article: PAIN. 2024;165(7):e65-e79
Unraveling the neuroimmune interface in chronic pain-the association between cytokines in the cerebrospinal fluid and pain in patients with lumbar disk herniation or degenerative disk disease
Rosenstrom AHC; Ahmed AS; Kultima K; Freyhult E; Berg S; Farinotti AB; Palada V; Svensson CI; Kosek E
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2023;113:212-227
Insights into FcγR involvement in pain-like behavior induced by an RA-derived anti-modified protein autoantibody
Jurczak A; Sandor K; Farinotti AB; Krock E; Hunt MA; Agalave NM; Barbier J; Simon N; Wang Z; Rudjito R; Vazquez-Mora JA; Martinez-Martinez A; Raoof R; Eijkelkamp N; Gronwall C; Klareskog L; Jimenez-Andrade JM; Marchand F; Svensson CI
Article: ADVANCED HEALTHCARE MATERIALS. 2023;12(24):e2300550
Flexible Organic Electronic Ion Pump Fabricated Using Inkjet Printing and Microfabrication for Precision In Vitro Delivery of Bupivacaine
Cherian D; Roy A; Farinotti AB; Abrahamsson T; Sjostrom TA; Tybrandt K; Nilsson D; Berggren M; Svensson CI; Poxson DJ; Simon DT
Article: ADVANCED THERAPEUTICS. 2023;6(7)
Electrophoretic Delivery of Clinically Approved Anesthetic Drug for Chronic Pain Therapy
Roy A; Farinotti AB; Sjostrom TA; Abrahamsson T; Cherian D; Karaday M; Tybrandt K; Nilsson D; Berggren M; Poxson DJ; Svensson CI; Simon DT
Article: PLOS PATHOGENS. 2021;17(5):e1009553
UPEC kidney infection triggers neuro-immune communication leading to modulation of local renal inflammation by splenic IFNγ
Steiner SE; Choong FX; Antypas H; Morado-Urbina CE; Schulz A; Farinotti AB; Bas DB; Svensson CI; Richter-Dahlfors A; Melican K
Article: PAIN. 2021;162(2):446-458
Sex-dependent role of microglia in disulfide high mobility group box 1 protein-mediated mechanical hypersensitivity
Agalave NM; Rudjito R; Farinotti AB; Khoonsari PE; Sandor K; Nomura Y; Szabo-Pardi TA; Urbina CM; Palada V; Price TJ; Harris HE; Burton MD; Kultima K; Svensson CI
Article: PAIN. 2021;162(2):459-470
Sex- and cell-dependent contribution of peripheral high mobility group box 1 and TLR4 in arthritis-induced pain
Rudjito R; Agalave NM; Farinotti AB; Lundback P; Szabo-Pardi TA; Price TJ; Harris HE; Burton MD; Svensson CI
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2019;216(8):1904-1924
Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons
Farinotti AB; Wigerblad G; Nascimento D; Bas DB; Urbina CM; Nandakumar KS; Sandor K; Xu B; Abdelmoaty S; Hunt MA; Moller KA; Baharpoor A; Sinclair J; Jardemark K; Lanner JT; Khmaladze I; Borm LE; Zhang L; Wermeling F; Cragg MS; Lengqvist J; Chabot-Dore A-J; Diatchenko L; Belfer I; Collin M; Kultima K; Heyman B; Miguel Jimenez-Andrade J; Codeluppi S; Holmdahl R; Svensson CI
Article: HEART. 2018;104(24):2026-2034
Cardiomyopathy, oxidative stress and impaired contractility in a rheumatoid arthritis mouse model
Pironti G; Bersellini-Farinotti A; Agalave NM; Sandor K; Fernandez-Zafra T; Jurczak A; Lund LH; Svensson CI; Andersson DC
Article: BASIC RESEARCH IN CARDIOLOGY. 2016;111(3):34
Dietary nitrate improves cardiac contractility via enhanced cellular Ca²⁺ signaling
Pironti G; Ivarsson N; Yang J; Farinotti AB; Jonsson W; Zhang S-J; Bas D; Svensson CI; Westerblad H; Weitzberg E; Lundberg JO; Pernow J; Lanner J; Andersson DC
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):730-738
Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism
Wigerblad G; Bas DB; Fernades-Cerqueira C; Krishnamurthy A; Nandakumar KS; Rogoz K; Kato J; Sandor K; Su J; Miguel Jimenez-Andrade J; Finn A; Farinotti AB; Amara K; Lundberg K; Holmdahl R; Jakobsson P-J; Malmstrom V; Catrina AI; Klareskog L; Svensson CI

All other publications

Thesis / dissertation: 2019
Antibody activation of sensory neurons : exploring novel pain mechanisms in rheumatoid arthritis
Bersellini Farinotti, Alex
Editorial comment: NEURON. 2018;97(4):729-731
Autoantibodies Hurt: Transfer of Patient-Derived CASPR2 Antibodies Induces Neuropathic Pain in Mice
Hunt MA; Nascimento DSM; Farinotti AB; Svensson CI
Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):598A-599A
Enhanced Cardiac Contractility and Ca²⁺ Signalling Following Dietary Nitrate Supplementation in Mice
Ivarsson N; Pironti G; Yang J; Farinotti AB; Jonsson W; Svensson C; Westerblad H; Weitzberg E; Lundberg J; Pernow J; Lanner J; Andersson DC

Employments

Research Specialist, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Physiology and Pharmacology, Karolinska Institutet, 2020

About me

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Degrees and Education

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