Alessandro Gasparini

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About me

I am a post-doctoral researcher in Biostatistics, working with Keith Humphreys on developing and extending statistical models for breast cancer growth and spread.

Other research interests cover the areas of survival analysis, statistical simulation, longitudinal data analysis, joint longitudinal-survival modelling, statistical issues in electronic health records data, kidney disease epidemiology.

My PhD thesis focussed on studying multilevel statistical methods applied in the settings of electronic health records. A digital copy can be found here.

Education
- PhD in Biostatistics (2020), University of Leicester

- MSc in Biostatistics and Experimental Statistics (2015), Università degli Studi di Milano-Bicocca

- BSc in Statistics and Experimental Statistics (2012), Università degli Studi di Padova

Articles

Article: JOURNAL OF INTERNAL MEDICINE. 2024;296(1):53-67
Early transfusion patterns improve the Molecular International Prognostic Scoring System (IPSS-M) prediction in myelodysplastic syndromes
Creignou M; Bernard E; Gasparini A; Tranberg A; Todisco G; Moura PL; Ejerblad E; Nilsson L; Garelius H; Antunovic P; Lorenz F; Rasmussen B; Walldin G; Mortera-Blanco T; Jansson M; Tobiasson M; Elena C; Ferrari J; Galli A; Pozzi S; Malcovati L; Edgren G; Crowther MJ; Jaedersten M; Papaemmanuil E; Hellstroem-Lindberg E
Article: BMC MEDICAL RESEARCH METHODOLOGY. 2024;24(1):6
Re-expressing coefficients from regression models for inclusion in a meta-analysis.
Linakis MW; Van Landingham C; Gasparini A; Longnecker MP
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2022;31(12):2415-2430
A natural history and copula-based joint model for regional and distant breast cancer metastasis
Gasparini A; Humphreys K
Article: BMC MEDICINE. 2022;20(1):420
The presence and impact of multimorbidity clusters on adverse outcomes across the spectrum of kidney function
Sullivan MK; Carrero J-J; Jani BD; Anderson C; McConnachie A; Hanlon P; Nitsch D; McAllister DA; Mair FS; Mark PB; Gasparini A
Article: STATISTICAL METHODS IN MEDICAL RESEARCH. 2022;31(5):862-881
Estimating latent, dynamic processes of breast cancer tumour growth and distant metastatic spread from mammography screening data
Gasparini A; Humphreys K
Article: BREAST CANCER RESEARCH. 2022;24(1):15
Assessing lead time bias due to mammography screening on estimates of loss in life expectancy
Syriopoulou E; Gasparini A; Humphreys K; Andersson TM-L
Article: CKJ: CLINICAL KIDNEY JOURNAL. 2022;15(3):442-451
Use of nephrotoxic medications in adults with chronic kidney disease in Swedish and US routine care
Bosi A; Xu Y; Gasparini A; Wettermark B; Barany P; Bellocco R; Inker LA; Chang AR; McAdams-DeMarco M; Grams ME; Shin J-I; Carrero JJ
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(2):275-280
Arteriovenous access placement and renal function decline
Lundstrom UH; Hedin U; Gasparini A; Caskey FJ; Carrero J-J; Evans M
Article: CRITICAL CARE EXPLORATIONS. 2020;2(4):e0104
Assessing the Course of Organ Dysfunction Using Joint Longitudinal and Time-to-Event Modeling in the Vasopressin and Septic Shock Trial.
Harhay MO; Gasparini A; Walkey AJ; Weissman GE; Crowther MJ; Ratcliffe SJ; Russell JA
Article: STATISTICS IN MEDICINE. 2019;38(23):4477-4502
Impact of model misspecification in shared frailty survival models
Gasparini A; Clements MS; Abrams KR; Crowther MJ
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2019;34(9):1534-1541
Plasma potassium ranges associated with mortality across stages of chronic kidney disease: the Stockholm CREAtinine Measurements (SCREAM) project
Gasparini A; Evans M; Barany P; Xu H; Jernberg T; Arnlov J; Lund LH; Carrero J-J
Article: AMERICAN JOURNAL OF KIDNEY DISEASES. 2019;73(2):206-217
Relationship of Estimated GFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-analysis in a Global Consortium
Inker LA; Grams ME; Levey AS; Coresh J; Cirillo M; Collins JF; Gansevoort RT; Gutierrez OM; Hamano T; Heine GH; Ishikawa S; Jee SH; Kronenberg F; Landray MJ; Miura K; Nadkarni GN; Peralta CA; Rothenbacher D; Schaeffner E; Sedaghat S; Shlipak MG; Zhang L; van Zuilen AD; Hallan SI; Kovesdy CP; Woodward M; Levin A; Astor B; Appel LJ; Greene T; Chen TK; Chalmers J; Arima H; Perkovic V; Yatsuya H; Tamakoshi K; Li Y; Hirakawa Y; Matsushita K; Grams M; Sang Y; Polldnghorne K; Chadban S; Atkins R; Djurdjev O; Liu L; Zhao M-H; Wang F; Wang J; Ebert N; Martus P; Tang M; Heine G; Emrich I; Seiler S; Zawada A; Nally J; Navaneethan SD; Schold JD; Zhao M; Sarnak MJ; Katz R; Hiramoto J; Iso H; Yamagishi K; Umesawa M; Murald I; Fukagawa M; Maruyama S; Hasegawa T; Fujii N; Wheeler DC; Emberson J; Townend J; Landray M; Brenner H; Schottker B; Saum K-U; Fox C; Hwang S-J; Kottgen A; Schneider MP; Eckardt K-U; Green JA; Kirchner HL; Chang AR; Ho K; Ito S; Miyazaki M; Nakayama M; Yamada G; Irie F; Sairenchi T; Yano Y; Kotani K; Nakamura T; Kimm H; Mok Y; Chodick G; Shalev V; Wetzels JFM; Blankestijn PJ; van den Brand JA; Sarnak M; Peralta C; Kollerits B; Ritz E; Nitsch D; Roderick P; Fletcher A; Bottinger E; Ellis SB; Nadukuru R; Ueshima H; Okayama A; Miura K; Tanaka S; Okamura T; Kadota A; Kenealy T; Elley CR; Drury PL; Ohkubo T; Asayama K; Metold H; Kikuya M; Nelson RG; Knowler WC; Bakker SJL; Hak E; Heerspink HJL; Brunskill NJ; Major RW; Shepherd D; Medcalf JF; Bernardo R; Jassal SK; Bergstrom J; Ix JH; Barrett-Connor E; Kalantar-Zadeh K; Sumida K; Muntner P; Warnock D; McClellan W; de Zeeuw D; Brenner B; Ikram MA; Hoorn EJ; Dehghan A; Carrero JJ; Gasparini A; Wettermark B; Elinder C-G; Wong TY; Sabanayagam C; Cheng C-Y; Sokor RBBMA; Visseren FLJ; Evans M; Segelmark M; Stendahl M; Schon S; Tangri N; Sud M; Naimark DM; Wen C-P; Tsao C-K; Tsai M-K; Chen C-H; Konta T; Hirayama A; Ichikawa K; Lannfelt L; Larsson A; Arnlov J; Bilo HJG; Landman GWD; van Hateren KJJ; Kleefstra N; Hallan S; Ballew SH; Chen J; Kwak L; Surapaneni A
Article: PLOS ONE. 2019;14(1):e0209440
Causes of death across categories of estimated glomerular filtration rate: The Stockholm CREAtinine Measurements (SCREAM) project
Runesson B; Qureshi AR; Xu H; Gasparini A; Lindholm B; Barany P; Elinder CG; Carrero JJ
Article: CKJ: CLINICAL KIDNEY JOURNAL. 2018;11(2):254-258
A scheme based on ICD-10 diagnoses and drug prescriptions to stage chronic kidney disease severity in healthcare administrative records
Friberg L; Gasparini A; Carrero JJ
Article: SCIENTIFIC REPORTS. 2018;8(1):5148
Lower serum calcium is independently associated with CKD progression
Janmaat CJ; van Diepen M; Gasparini A; Evans M; Qureshi AR; Arnlov J; Barany P; Elinder C-G; Rotmans JI; Vervloet M; Dekker FW; Carrero JJ
Article: SCIENTIFIC REPORTS. 2018;8(1):2103
Cinacalcet use and the risk of cardiovascular events, fractures and mortality in chronic kidney disease patients with secondary hyperparathyroidism
Evans M; Methven S; Gasparini A; Barany P; Birnie K; MacNeill S; May MT; Caskey FJ; Carrero J-J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;245:277-284
Incidence and determinants of hyperkalemia and hypokalemia in a large healthcare system
Nilsson E; Gasparini A; Arnlov J; Xu H; Henriksson KM; Coresh J; Grams ME; Carrero JJ
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;245:20-26
Outcomes associated to serum phosphate levels in patients with suspected acute coronary syndrome
Xu H; Evans M; Gasparini A; Szummer K; Spaak J; Arnlov J; Lindholm B; Jernberg T; Carrero JJ
Article: AMERICAN SOCIETY OF NEPHROLOGY. CLINICAL JOURNAL. 2017;12(9):1399-1408
eGFR and the Risk of Community-Acquired Infections
Xu H; Gasparini A; Ishigami J; Mzayen K; Su G; Barany P; Arnlov J; Lindholm B; Elinder CG; Matsushita K; Carrero JJ
Article: GASTROENTEROLOGY. 2017;153(3):702-710
Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease
Klatte DCF; Gasparini A; Xu H; de Deco P; Trevisan M; Johansson ALV; Wettermark B; Arnlov J; Janmaat CJ; Lindholm B; Dekker FW; Coresh J; Grams ME; Carrero JJ
Article: THE LANCET DIABETES AND ENDOCRINOLOGY. 2017;5(9):718-728
Measures of chronic kidney disease and risk of incident peripheral artery disease: a collaborative meta-analysis of individual participant data
Matsushita K; Ballew SH; Coresh J; Arima H; Arnlov J; Cirillo M; Ebert N; Hiramoto JS; Kimm H; Shlipak MG; Visseren FLJ; Gansevoort RT; Kovesdy CP; Shalev V; Woodward M; Kronenberg F
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2017;6(7):e005428
Hyperkalemia After Initiating Renin-Angiotensin System Blockade: The Stockholm Creatinine Measurements (SCREAM) Project
Bandak G; Sang Y; Gasparini A; Chang AR; Ballew SH; Evans M; Arnlov J; Lund LH; Inker LA; Coresh J; Carrero J-J; Grams ME
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2017;32(suppl_2):170-179
Routinely measured iohexol glomerular filtration rate versus creatinine-based estimated glomerular filtration rate as predictors of mortality in patients with advanced chronic kidney disease: a Swedish Chronic Kidney Disease Registry cohort study
Methven S; Gasparini A; Carrero JJ; Caskey FJ; Evans M
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2017;6(3):e004925
Time in Therapeutic Range and Outcomes After Warfarin Initiation in Newly Diagnosed Atrial Fibrillation Patients With Renal Dysfunction
Szummer K; Gasparini A; Eliasson S; Arnlov J; Qureshi AR; Barany P; Evans M; Friberg L; Carrero JJ
Article: BMC NEPHROLOGY. 2017;18(1):59
Low renal replacement therapy incidence among slowly progressing elderly chronic kidney disease patients referred to nephrology care: an observational study
Lundstrom UH; Gasparini A; Bellocco R; Qureshi AR; Carrero J-J; Evans M
Article: KIDNEY INTERNATIONAL. 2017;91(1):244-251
Albuminuria changes are associated with subsequent risk of end-stage renal disease and mortality
Carrero JJ; Grams ME; Sang Y; Arnlov J; Gasparini A; Matsushita K; Qureshi AR; Evans M; Barany P; Lindholm B; Ballew SH; Levey AS; Gansevoort RT; Elinder CG; Coresh J
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2016;31(12):2086-2094
Prevalence and recognition of chronic kidney disease in Stockholm healthcare
Gasparini A; Evans M; Coresh J; Grams ME; Norin O; Qureshi AR; Runesson B; Barany P; Arnlov J; Jernberg T; Wettermark B; Elinder CG; Carrero J-J
Article: CKJ: CLINICAL KIDNEY JOURNAL. 2016;9(1):119-127
The Stockholm CREAtinine Measurements (SCREAM) project: protocol overview and regional representativeness
Runesson B; Gasparini A; Qureshi AR; Norin O; Evans M; Barany P; Wettermark B; Elinder CG; Carrero JJ
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All other publications

Review: KIDNEY INTERNATIONAL. 2023;103(1):53-69
Defining measures of kidney function in observational studies using routine health care data: methodological and reporting considerations
Carrero JJ; Fu EL; Vestergaard SV; Jensen SK; Gasparini A; Mahalingasivam V; Bell S; Birn H; Heide-Jorgensen U; Clase CM; Cleary F; Coresh J; Dekker FW; Gansevoort RT; Hemmelgarn BR; Jager KJ; Jafar TH; Kovesdy CP; Sood MM; Stengel B; Christiansen CF; Iwagami M; Nitsch D
Published conference paper: STATISTICA NEERLANDICA. 2020;74(1):5-23
Editorial
Gasparini A; Abrams KR; Barrett JK; Major RW; Sweeting MJ; Brunskill NJ; Crowther MJ

Employments

Affiliated to Research, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 2022-2025

Supervisor

Letizia Orsini, 2022

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