Aleksandra Mandic Havelka

Publications
CV
Public outreach and news

Articles

Article: ACTA PAEDIATRICA, INTERNATIONAL JOURNAL OF PAEDIATRICS. 2010;99(6):836-841
Maternal plasma level of antimicrobial peptide LL37 is a major determinant factor of neonatal plasma LL37 level
Havelka AM; Yektaei-Karin E; Hultenby K; Sorensen OE; Lundahl J; Berggren V; Marchini G
Article: INTERNATIONAL JOURNAL OF CANCER. 2009;124(6):1463-1469
Induction of the lysosomal apoptosis pathway by inhibitors of the ubiquitin-proteasome system
Berndtsson M; Beaujouin M; Rickardson L; Havelka AM; Larsson R; Westman J; Liaudet-Coopman E; Linder S
Article: BMC CHEMICAL BIOLOGY. 2008;8:2
Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase II.
Olofsson MH; Havelka AM; Brnjic S; Shoshan MC; Linder S
Article: CLINICAL CANCER RESEARCH. 2007;13(11):3198-3206
Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy
Olofsson MH; Ueno T; Pan Y; Xu R; Cai F; van der Kuip H; Muerdter TE; Sonnenberg M; Aulitzk WE; Schwarz S; Andersson E; Shoshan MC; Havelka AM; Toi M; Linder S
Article: INTERNATIONAL JOURNAL OF CANCER. 2007;120(1):175-180
Acute apoptosis by cisplatin requires induction of reactive oxygen species but is not associated with damage to nuclear DNA
Berndtsson M; Hagg M; Panaretakis T; Havelka AM; Shoshan MC; Linder S
Article: BRITISH JOURNAL OF CANCER. 2006;94(11):1592-1598
Docetaxel induces apoptosis in hormone refractory prostate carcinomas during multiple treatment cycles
Kramer G; Schwarz S; Hagg M; Havelka AM; Linder S
Article: FEBS LETTERS. 2005;579(14):3090-3094
Phosphorylation of BAD at Ser-128 during mitosis and paclitaxel-induced apoptosis
Berndtsson M; Konishi Y; Bonni A; Hägg M; Shoshan M; Linder S; Havelka AM
Article: JOURNAL OF IMMUNOLOGY. 2005;174(10):6080-6087
Preferential cell death of CD8⁺ effector memory (CCR7^-CD45RA^-) T cells by hydrogen peroxide-induced oxidative stress
Takahashi A; Hanson MGV; Norell HR; Havelka AM; Kono K; Malmberg KJ; Kiessling RVR
Article: MOLECULAR CANCER THERAPEUTICS. 2004;3(4):489-497
Induction of endoplasmic reticulum stress by ellipticine plant alkaloids
Hägg M; Berndtsson M; Mandic A; Zhou R; Shoshan MC; Linder S
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(11):9100-9106
Cisplatin induces endoplasmic reticulum stress and nucleus-independent apoptotic signaling
Mandic A; Hansson J; Linder S; Shoshan MC
Article: MOLECULAR AND CELLULAR BIOLOGY. 2002;22(9):3003-3013
Calpain-mediated bid cleavage and calpain-independent Bak modulation: Two separate pathways in cisplatin-induced apoptosis
Mandic A; Viktorsson K; Strandberg L; Heiden T; Hansson J; Linder S; Shoshan MC
Article: MOLECULAR AND CELLULAR BIOLOGY. 2001;21(11):3684-3691
Cisplatin induces the proapoptotic conformation of Bak in a ΔMEKK1-dependent manner
Mandic A; Viktorsson K; Molin M; Akusjärvi G; Eguchi H; Hayashi SI; Toi M; Hansson J; Linder S; Shoshan MC
Article: MELANOMA RESEARCH. 2001;11(1):11-19
The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis
Mandic A; Viktorsson K; Heiden T; Hansson J; Shoshan MC

All other publications

Review: MOLECULAR BIOSYSTEMS. 2010;6(5):767-774
Chemical biology suggests a role for calcium signaling in mediating sustained JNK activation during apoptosis
Brnjic S; Olofsson MH; Havelka AM; Linder S
Review: MINI-REVIEWS IN MEDICINAL CHEMISTRY. 2007;7(10):1035-1039
Mechanisms of action of DNA-damaging anticancer drugs in treatment of carcinomas: Is acute apoptosis an "off-target" effect?
Havelka AM; Berndtsson M; Olofsson MH; Shoshan MC; Linder S
Review: EXPERT OPINION ON DRUG DISCOVERY. 2006;1(6):585-594
Sense and sensibility: the use of cell death biomarker assays in high-throughput anticancer drug screening and monitoring treatment responses
Shoshan MC; Havelka AM; Neumann F; Linder S
Review: CANCER LETTERS. 2004;214(1):1-9
Determining tumor apoptosis and necrosis in patient serum using cytokeratin 18 as a biomarker
Linder S; Havelka AM; Ueno T; Shoshan MC
Thesis / dissertation: 2003
Elucidation of pro-apoptotic signaling induced by cisplatin
Mandic, Aleksandra

Employments

Affiliated to Research, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2024-2027

Degrees and Education

Doctor Of Philosophy, Department of Oncology-Pathology, Karolinska Institutet, 2003

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