Alejandra Machado

About me
Publications
Grants
Public outreach and news

Research

My previous research work focused on Normal Aging and Neurodegenerative disorders such as Alzheimer’s Disease (AD), with a focus on the multidimensional and integrative study of cognitive, clinical, socio-demographic, and neuroimaging factors.

Since 2020 I have extended my research to the field of insurance medicine, focusing on risk factors for and consequences of sickness absence in relation to multiple sclerosis (MS).

Articles

Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2024;34(Suppl 3):ckae144.1301
Impact of Multiple Sclerosis on different life dimensions among working women in Sweden
Machado A; Teni FS; Friberg E
Journal article: OCCUPATIONAL MEDICINE. 2024;74(Supplement_1):0
P-625 NON-STANDARD FORMS OF EMPLOYMENT AMONG PEOPLE WITH MULTIPLE SCLEROSIS IN SWEDEN: A SURVEY PERSPECTIVE
Machado A; Friberg E
Journal article: OCCUPATIONAL MEDICINE. 2024;74(Supplement_1):0
P-309 NON-PHARMACOLOGICAL INTERVENTIONS FOR WORK PARTICIPATION IN PEOPLE WITH MULTIPLE SCLEROSIS
Saddal S; Van der Hiele K; Machado A; De Perez BD; Friberg E; Nair RD; Benedict R; Radford K; Daams J; Hulst H; De Groot V; Schaafsma F
Article: JOURNAL OF OCCUPATIONAL REHABILITATION. 2024;34(2):461-471
Work Adjustments by Types of Occupations Amongst People with Multiple Sclerosis: A Survey Study
Machado A; Murley C; Dervish J; Teni FS; Friberg E
Article: BMC PUBLIC HEALTH. 2024;24(1):1389
Exploring the working life of people with multiple sclerosis during the COVID-19 pandemic in Sweden
Murley C; Dervish J; Machado A; Svard V; Wennman-Larsen A; Hillert J; Friberg E
Article: MULTIPLE SCLEROSIS JOURNAL - EXPERIMENTAL, TRANSLATIONAL AND CLINICAL. 2024;10(2):20552173241248293
Coronavirus disease 2019 infection among working-aged people with multiple sclerosis and the impact of disease-modifying therapies
Murley C; Pettersson E; Hillert J; Machado A; Friberg E
Article: MULTIPLE SCLEROSIS JOURNAL. 2024;30(3):419-431
Recent trends in disease-modifying therapy use and associated sickness absence and disability pension among people with multiple sclerosis in Sweden
Teni FS; Machado A; Fink K; Gyllensten H; Hillert J; Friberg E
Article: FRONTIERS IN PUBLIC HEALTH. 2024;12:1331746
Disclosing or concealing multiple sclerosis in the workplace: two sides of the same coin-insights from a Swedish population-based survey
Dervish J; Arfuch VM; Murley C; Mckay KA; Machado A; Wennman-Larsen A; Friberg E
Article: EUROPEAN JOURNAL OF HEALTH ECONOMICS. 2023;24(8):1357-1371
Excess costs of multiple sclerosis: a register-based study in Sweden
Murley C; Tinghog P; Teni FS; Machado A; Alexanderson K; Hillert J; Karampampa K; Friberg E
Article: NEUROLOGY. 2023;101(3):e277-e288
Association of Chronic Kidney Disease With Plasma NfL and Other Biomarkers of Neurodegeneration The H70 Birth Cohort Study in Gothenburg
Dittrich A; Ashton NJJ; Zetterberg H; Blennow K; Zettergren A; Simren J; Skillback T; Shams S; Machado A; Westman E; Scholl M; Skoog I; Kern S
Article: EUROPEAN JOURNAL OF NEUROLOGY. 2023;30(7):1843-1853
Self-reported restrictions in different life domains and associated factors among people with multiple sclerosis in Sweden
Teni FS; Machado A; Murley C; Fink K; Gyllensten H; Dervish J; Hillert J; Friberg E
Journal article: ALZHEIMER'S AND DEMENTIA. 2023;19(S2)
Biomarker evidence of neurodegeneration in chronic kidney disease, in a general population
Dittrich A; Ashton NJ; Zetterberg H; Blennow K; Zettergren A; Simrén J; Shams S; Machado A; Westman E; Schöll M; Skoog I; Kern S
Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2023;69:104456
Trajectories of disease-modifying therapies and associated sickness absence and disability pension among 1923 people with multiple sclerosis in Sweden
Teni FS; Machado A; Murley C; He A; Fink K; Gyllensten H; Glaser A; Alexanderson K; Hillert J; Friberg E
Article: PLOS ONE. 2023;18(8):e0288998
Gender differences in earnings among people with multiple sclerosis and associations with type of occupation and family composition: A population-based study with matched references
Machado A; Azad A; Pettersson E; Hillert JV; Alexanderson KV; Friberg EV
Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2022;32(Supplement_3):ckac129.097
Excess costs of multiple sclerosis: A register-based study in Sweden
Murley C; Tinghög P; Teni FS; Machado A; Alexanderson K; Hillert J; Karampampa K; Friberg E
Article: NEUROLOGY. 2022;99(15):e1619-e1629
Association of Cerebrovascular and Alzheimer Disease Biomarkers With Cholinergic White Matter Degeneration in Cognitively Unimpaired Individuals
Cedres N; Ferreira D; Nemy M; Machado A; Pereira JB; Shams S; Wahlund L-O; Zettergren A; Stepankova O; Vyslouzilova L; Eriksdotter M; Teipel S; Grothe MJ; Blennow K; Zetterberg H; Scholl M; Kern S; Skoog I; Westman E
Article: ACTA NEUROLOGICA SCANDINAVICA. 2022;146(3):283-294
Self-employment, sickness absence, and disability pension in multiple sclerosis
Machado A; Murley C; Hillert J; Alexanderson K; Friberg E
Article: MULTIPLE SCLEROSIS JOURNAL. 2022;28(9):1402-1413
Trajectories of sickness absence and disability pension days among people with multiple sclerosis by type of occupation
Bosma AR; Murley C; Aspling J; Hillert J; Schaafsma FG; Anema JR; Boot CRL; Alexanderson K; Machado A; Friberg E
Article: JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY. 2022;28(2):188-202
Swedish Normative Data for Mindmore: A Comprehensive Cognitive Screening Battery, Both Digital and Self-Administrated
van den Hurk W; Bergman I; Machado A; Bjermo J; Gustavsson A
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2022;14(1):e12295
Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community-based sample of 70-year-olds
Dittrich A; Ashton NJ; Zetterberg H; Blennow K; Simren J; Geiger F; Zettergren A; Shams S; Machado A; Westman E; Scholl M; Skoog I; Kern S
Journal article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2022;32
Excess costs of multiple sclerosis: A register-based study in Sweden
Murley C; Tinghog P; Teni FSS; Machado A; Alexanderson K; Hillert J; Karampampa K; Friberg E
Journal article: ALZHEIMER'S AND DEMENTIA. 2021;17(S5)
The association of Alzheimer’s disease and cerebrovascular disease biomarkers towards the neurodegeneration of the cholinergic pathways
Cedres N; Ferreira D; Nemy M; Machado A; Pereira JB; Wahlund L; Zettergren A; Teipel SJ; Grothe MJ; Eriksdotter M; Stepankova O; Vyslouzilova L; Blennow K; Zetterberg H; Kern S; Skoog I; Westman E
Article: NEUROBIOLOGY OF AGING. 2021;101:1-12
Effects of amyloid pathology and the APOE ε4 allele on the association between cerebrospinal fluid Aβ38 and Aβ40 and brain morphology in cognitively normal 70-years-olds
Lindberg O; Kern S; Skoog J; Machado A; Pereira JB; Sacuiu SF; Wahlund L-O; Blennow K; Zetterberg H; Zettergren A; Westman E; Skoog I
Article: ALZHEIMER'S AND DEMENTIA: DIAGNOSIS, ASSESSMENT AND DISEASE MONITORING. 2021;13(1):e12141
Sex differences in CSF biomarkers for neurodegeneration and blood-brain barrier integrity
Skillback T; Blennow K; Zetterberg H; Shams S; Machado A; Pereira J; Lindberg O; Mielke MM; Zettergren A; Ryden L; Westman E; Wahlund L-O; Skoog I; Kern S
Journal article: ALZHEIMER'S AND DEMENTIA. 2020;16(S4)
Sex differences in CSF biomarkers for neurodegeneration and blood‐brain barrier integrity
Skillback T; Blennow K; Zetterberg H; Shams S; Machado A; Pereira JB; Lindberg O; Mielke MM; Zettergren A; Rydén L; Westman E; Wahlund L; Skoog I; Kern S
Article: ALZHEIMER'S RESEARCH AND THERAPY. 2020;12(1):51
The cholinergic system in subtypes of Alzheimer's disease: an in vivo longitudinal MRI study
Machado A; Ferreira D; Grothe MJ; Eyjolfsdottir H; Almqvist PM; Cavallin L; Lind G; Linderoth B; Seiger A; Teipel S; Wahlberg LU; Wahlund L-O; Westman E; Eriksdotter M
Article: AGING. 2020;12(1):894-901
Predicting Fazekas scores from automatic segmentations of white matter signal abnormalities
Cedres N; Ferreira D; Machado A; Shams S; Sacuiu S; Waern M; Wahlund L-O; Zettergren A; Kern S; Skoog I; Westman E
Article: JOURNAL OF ALZHEIMER'S DISEASE. 2019;68(1):295-309
Subjective Cognitive Decline Below and Above the Age of 60: A Multivariate Study on Neuroimaging, Cognitive, Clinical, and Demographic Measures
Cedres N; Machado A; Molina Y; Diaz-Galvan P; Andres Hernandez-Cabrera J; Barroso J; Westman E; Ferreira D
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY (EJE). 2019;34(2):191-209
The Gothenburg H70 Birth cohort study 2014-16: design, methods and study population
Sterner TR; Ahlner F; Blennow K; Dahlin-Ivanoff S; Falk H; Johansson LH; Hoff M; Holm M; Horder H; Jacobsson T; Johansson B; Johansson L; Kern J; Kern S; Machado A; Fassberg MM; Nilsson J; Ribbe M; Rothenberg E; Ryden L; Sadeghi A; Sacuiu S; Samuelsson J; Sigstrom R; Skoog J; Thorvaldsson V; Waern M; Westman E; Wetterberg H; Zetterberg H; Zetterberg M; Zettergren A; Ostling S; Skoog I
Article: FRONTIERS IN PSYCHOLOGY. 2019;10:2327
Comparing Traditional and Digitized Cognitive Tests Used in Standard Clinical Evaluation - A Study of the Digital Application Minnemera
Bjorngrim S; van den Hurk W; Betancort M; Machado A; Lindau M
Article: NEUROBIOLOGY OF AGING. 2018;71:179-188
Proposal for a hierarchical, multidimensional, and multivariate approach to investigate cognitive aging
Machado A; Barroso J; Molina Y; Nieto A; Diaz-Flores L; Westman E; Ferreira D
Article: HIPPOCAMPUS. 2017;27(6):653-667
The interactive effect of demographic and clinical factors on hippocampal volume: A multicohort study on 1958 cognitively normal individuals
Ferreira D; Hansson O; Barroso J; Molina Y; Machado A; Andres Hernandez-Cabrera J; Muehlboeck J-S; Stomrud E; Nagga K; Lindberg O; Ames D; Kalpouzos G; Fratiglioni L; Backman L; Graff C; Mecocci P; Vellas B; Tsolaki M; Kloszewska I; Soininen H; Lovestone S; Ahlstrom H; Lind L; Larsson E-M; Wahlund L-O; Simmons A; Westman E
Article: FRONTIERS IN AGING NEUROSCIENCE. 2017;9:188
Cognitive Variability during Middle-Age: Possible Association with Neurodegeneration and Cognitive Reserve
Ferreira D; Machado A; Molina Y; Nieto A; Correia R; Westman E; Barroso J
Article: BEHAVIOURAL BRAIN RESEARCH. 2016;311:375-383
Different reserve proxies confer overlapping and unique endurance to cortical thinning in healthy middle-aged adults
Ferreira D; Bartres-Faz D; Nygren L; Rundkvist LJ; Molina Y; Machado A; Junque C; Barroso J; Westman E
Article: PSICOTHEMA. 2015;27(3):216-222
Cognitive decline before the age of 50 can be detected with sensitive cognitive measures
Ferreira D; Correia R; Nieto A; Machado A; Molina Y; Barroso J
Article: REVISTA DE NEUROLOGIA. 2014;58(9):389-395
Alternate form of the test de aprendizaje verbal Espana-Complutense (TAVEC)
Nieto A; Hernandez-Rodriguez E; Hernandez-Torres A; Velasco Rodriguez-Solis P; Hess-Medler S; Machado-Fernandez A; Molina-Rodriguez Y; Barroso J
Article: NEUROBIOLOGY OF AGING. 2014;35(5):1086-1094
Cognitive decline is mediated by gray matter changes during middle age
Ferreira D; Molina Y; Machado A; Westman E; Wahlund L-O; Nieto A; Correia R; Junque C; Diaz-Flores L; Barroso J
Show more

All other publications

Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:433-434
Risk of diagnostic delay in multiple sclerosis associated with sickness absence during the prodromal phase of the disease
Machado A; Alexanderson K; Hillert J; Friberg E
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2023;29:452-453
Covid-19 susceptibility and disease modifying therapies on working-aged individuals with multiple sclerosis: a survey study
Murley C; Pettersson E; Hillert J; Machado A; Friberg E
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):672-673
Trajectories of disease-modifying therapies and associated sickness absence and disability pension among people with multiple sclerosis
Teni FS; Machado A; Murley C; He A; Fink K; Gyllensten H; Glaser A; Alexanderson K; Hillert J; Friberg E
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):207-208
Working life of people with multiple sclerosis during the COVID-19 pandemic: a cross-sectional survey of working-aged people with multiple sclerosis in Sweden
Murley C; Machado A; Hillert J; Friberg E
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2022;28(3_SUPPL):200-201
Limitations in different life domains early in the disease course among people with multiple sclerosis in Sweden
Teni FS; Machado A; Murley C; Fink K; Gyllensten H; Dervish J; Hillert J; Friberg E
Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2021;31:459
Sickness absence and disability pension within different employment status in multiple sclerosis
Machado A; Murley C; Hillert J; Alexanderson K; Friberg E
Conference publication: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2021;31:ckab164.725
Trajectories of sickness absence and disability pension by type of occupation in multiple sclerosis
Bosma A; Murley C; Aspling J; Hillert J; Schaafsma F; Anema J; Boot CRL; Alexanderson K; Machado A; Friberg E
Preprint: MEDRXIV. 2020
The cholinergic system and treatment response in subtypes of Alzheimer’s disease
Machado A; Ferreira D; Grothe M; Eyjolfsdottir H; Almqvist P; Cavallin L; Lind G; Linderoth B; Seiger Å; Teipel S; Wahlberg L; Wahlund L-O; Westman E; Eriksdotter M; for the Alzheimer’s Disease Neuroimaging Initiativ
Letter: REVISTA DE NEUROLOGIA. 2014;59(10):480
Parallel version of the Spain-Complutense verbal learning test (TAVEC) Reply
Nieto A; Hernandez-Rodriguez E; Hernandez-Torres A; Velasco Rodriguez-Sols P; Hess-Medler S; Machado-Fernandez A; Molina-Rodriguez Y; Barroso J

Grants

Uncovering sustainable work strategies for individuals with Multiple Sclerosis
Swedish Research Council for Health Working Life and Welfare
1 January 2024 - 31 December 2026

Research

Articles

All other publications

Grants

News from KI

Events from KI