Akira Kaneko

About me
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About me

Based on achievements as malariologist in malaria elimination on islands in Vanuatu from 1987 to 1994, I have conducted research on malaria epidemiology, chemotherapy and elimination in Vanuatu, Papua New Gunea, Indonesia, Cambodia, Malawi, Zanzibar, Ghana, and recently the Lake Victoria area in Kenya. Since 2011, I am Professor of Global Health and leader of the Island Malaria Group at the Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet.

Articles

Journal article: TROPICAL MEDICINE AND HEALTH. 2024;52(1):52
Non-random distribution of Plasmodium Species infections and associated clinical features in children in the lake Victoria region, Kenya, 2012-2018
Omondi P; Musyoka B; Okai T; Kongere J; Kagaya W; Chan CW; Ngara M; Kanoi BN; Kido Y; Gitaka J; Kaneko A
Journal article: DRUG METABOLISM AND PHARMACOKINETICS. 2024;57:101029
Genetic variation present in the CYP3A4 gene in Ni-Vanuatu and Kenyan populations in malaria endemicity
Musyoka K; Chan CW; Rico EMG; Omondi P; Kijogi C; Okai T; Kongere J; Ngara M; Kagaya W; Kanoi BN; Hiratsuka M; Kido Y; Gitaka J; Kaneko A
Journal article: COMMUNICATIONS MEDICINE. 2024;4(1):91
Tracing the origins of Plasmodium vivax resurgence after malaria elimination on Aneityum Island in Vanuatu
Sekine S; Chan CW; Kalkoa M; Yamar S; Iata H; Taleo G; Kc A; Kagaya W; Kido Y; Kaneko A
Article: MALARIA JOURNAL. 2024;23(1):82
Malaria infection among adults residing in a highly endemic region from the Democratic Republic of the Congo
Kayiba NK; Nitahara Y; Tshibangu-Kabamba E; Mbuyi DK; Kabongo-Tshibaka A; Kalala NT; Tshiebue BM; Candray-Medina K-S; Kaku N; Nakagama Y; Speybroeck N; Mumba DN; Disashi GT; Kaneko A; Kido Y
Article: TRIALS. 2024;25(1):165
Evaluation of a financial incentive intervention on malaria prevalence among the residents in Lake Victoria basin, Kenya: study protocol for a cluster-randomized controlled trial
Matsumoto T; Nagashima M; Kagaya W; Kongere J; Gitaka J; Kaneko A
Article: SCIENTIFIC REPORTS. 2023;13(1):12062
High throughput human genotyping for variants associated with malarial disease outcomes using custom targeted amplicon sequencing
Osborne A; Phelan JEE; Vanheer LNN; Manjurano A; Gitaka J; Drakeley CJJ; Kaneko A; Kita K; Campino S; Clark TGG
Article: SCIENTIFIC REPORTS. 2023;13(1):11416
Drug resistance profiling of asymptomatic and low-density Plasmodium falciparum malaria infections on Ngodhe island, Kenya, using custom dual-indexing next-generation sequencing
Osborne A; Phelan JE; Kaneko A; Kagaya W; Chan C; Ngara M; Kongere J; Kita K; Gitaka J; Campino S; Clark TG
Article: TRIALS. 2023;24(1):354
Evaluation of the protective efficacy of Olyset®Plus ceiling net on reducing malaria prevalence in children in Lake Victoria Basin, Kenya: study protocol for a cluster-randomized controlled trial
Kagaya W; Chan CWW; Kongere J; Kanoi BNN; Ngara M; Omondi P; Osborne A; Barbieri L; Kc A; Minakawa N; Gitaka J; Kaneko A
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2023;13:1165634
Naturally acquired antibody response to Plasmodium falciparum and Plasmodium vivax among indigenous Orang Asli communities in Peninsular Malaysia
Rahim MAFA; Munajat MB; Dian ND; Seri Rakna MIM; Wahid W; Ghazali N; Hassan NW; Manap SNAA; Kasri MRM; Mohamed AI; Osman E; Chuangchaiya S; Lubis IND; Divis PCS; Kaneko A; Tetteh KKA; Idris ZM
Article: MALARIA JOURNAL. 2022;21(1):252
Potential application of the haematology analyser XN-31 prototype for field malaria surveillance in Kenya
Kagaya W; Takehara I; Kurihara K; Maina M; Chan CW; Okomo G; Kongere J; Gitaka J; Kaneko A
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2022;12:953585
Seroepidemiological surveillance, community perceptions and associated risk factors of malaria exposure among forest-goers in Northeastern Thailand
Rahim MAFA; Chuangchaiya S; Chanpum P; Palawong L; Kantee P; Dian ND; Lubis IND; Divis PCS; Kaneko A; Tetteh KKA; Idris ZM
Article: SCIENTIFIC REPORTS. 2021;11(1):19809
Characterizing the genomic variation and population dynamics of Plasmodium falciparum malaria parasites in and around Lake Victoria, Kenya
Osborne A; Manko E; Takeda M; Kaneko A; Kagaya W; Chan C; Ngara M; Kongere J; Kita K; Campino S; Kaneko O; Gitaka J; Clark TG
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2021;33(3):e23500
Relationships between mental health and diet during pregnancy and birth outcomes in a lower-middle income country: "Healthy mothers, healthy communities" study in Vanuatu
Therrien A-S; Buffa G; Roome AB; Standard E; Pomer A; Obed J; Taleo G; Tarivonda L; Chan CW; Kaneko A; Olszowy KM; Dancause KN
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020;17(19):E7351-7351
Relationships between Prenatal Distress and Infant Body Mass Index in the First Year of Life in a Lower-Middle Income Country
Therrien A-S; Buffa G; Roome AB; Standard E; Pomer A; Obed J; Taleo G; Tarivonda L; Chan CW; Kaneko A; Olszowy KM; Dancause KN
Article: DRUG METABOLISM AND PHARMACOKINETICS. 2020;35(1):89-101
CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity
Rico EMG; Kikuchi A; Saito T; Kumondai M; Hishinuma E; Kaneko A; Chan CW; Gitaka J; Nakayoshi T; Oda A; Saito S; Hirasawa N; Hiratsuka M
Article: SCIENTIFIC REPORTS. 2019;9(1):19060
Malaria resurgence after significant reduction by mass drug administration on Ngodhe Island, Kenya
Kagaya W; Gitaka J; Chan CW; Kongere J; Idris ZM; Deng C; Kaneko A
Article: ARCHIVES OF WOMEN'S MENTAL HEALTH. 2019;22(6):825-829
Psychosocial distress among women following a natural disaster in a low- to middle-income country: "healthy mothers, healthy communities" study in Vanuatu
Pomer A; Buffa G; Ayoub M-B; Taleo F; Sizemore JH; Tokon A; Chan CW; Kaneko A; Obed J; Iaruel J; Taleo G; Tarivonda L; Dancause KN
Article: PUBLIC HEALTH NUTRITION. 2019;22(9):1533-1544
Using multiple correspondence analysis to identify behaviour patterns associated with overweight and obesity in Vanuatu adults
van Horn A; Weitz CA; Olszowy KM; Dancause KN; Sun C; Pomer A; Silverman H; Lee G; Tarivonda L; Chan CW; Kaneko A; Lum JK; Garruto RM
Article: AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY. 2018;167(4):760-776
Coming to grips with economic development: Variation in adult hand grip strength during health transition in Vanuatu
Olszowy KM; Little MA; Lee G; Pomer A; Dancause KN; Sun C; Silverman H; Chan CW; Tarivonda L; Kaneko A; Weitz C; Lum JK; Garruto RM
Article: SCIENTIFIC REPORTS. 2018;8(1):5565
Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea
Mita T; Hombhanje F; Takahashi N; Sekihara M; Yamauchi M; Tsukahara T; Kaneko A; Endo H; Ohashi J
Article: ANNALS OF HUMAN BIOLOGY. 2018;45(3):220-228
Relationships between psychosocial distress and diet during pregnancy and infant birthweight in a lower-middle income country: "healthy mothers, healthy communities' study in Vanuatu
Pomer A; Buffa G; Taleo F; Sizemore JH; Tokon A; Taleo G; Tarivonda L; Chan CW; Kaneko A; Dancause KN
Article: MALARIA JOURNAL. 2018;17(1):72
Improvement of malaria diagnostic system based on acridine orange staining
Kimura M; Teramoto I; Chan CW; Idris ZM; Kongere J; Kagaya W; Kawamoto F; Asada R; Isozumi R; Kaneko A
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2017;29(5)
Secular change in adult stature associated with modernization in Vanuatu
Olszowy KM; Sun C; Silverman H; Pomer A; Dancause KN; Chan CW; Lee G; Tarivonda L; Kaneko A; Weitz C; Lum JK; Garruto RM
Article: SCIENTIFIC REPORTS. 2017;7(1):9123
Naturally acquired antibody response to Plasmodium falciparum describes heterogeneity in transmission on islands in Lake Victoria
Idris ZM; Chan CW; Kongere J; Hall T; Logedi J; Gitaka J; Drakeley C; Kaneko A
Article: PARASITES AND VECTORS. 2017;10(1):204
Serological measures to assess the efficacy of malaria control programme on Ambae Island, Vanuatu
Idris ZM; Chan CW; Mohammed M; Kalkoa M; Taleo G; Junker K; Arca B; Drakeley C; Kaneko A
Article: MALARIA JOURNAL. 2017;16(1):141
Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group
Thriemer K; Ley B; Bobogare A; Dysoley L; Alam MS; Pasaribu AP; Sattabongkot J; Jambert E; Domingo GJ; Commons R; Auburn S; Marfurt J; Devine A; Aktaruzzaman MM; Sohel N; Namgay R; Drukpa T; Sharma SN; Sarawati E; Samad I; Theodora M; Nambanya S; Ounekham S; Mudin RNB; Da Thakur G; Makita LS; Deray R; Lee S-E; Boaz L; Danansuriya MN; Mudiyanselage SD; Chinanonwait N; Kitchakarn S; Nausien J; Naket E; Thang ND; Ha DM; Hong YS; Cheng Q; Richards JS; Kusriastuti R; Satyagraha A; Noviyanti R; Ding XC; Khan WA; Phru CS; Zhu G; Qi G; Kaneko A; Miotto O; Nguitragool W; Roobsoong W; Battle K; Howes RE; Roca-Feltrer A; Duparc S; Bhowmick IP; Kenangalem E; Bibit J-A; Barry A; Sintasath D; Abeyasinghe R; Sibley CH; McCarthy J; von Seidlein L; Baird JK; Price RN
Article: ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH. 2017;29(3):180-188
Rolling Tobacco in Banana Leaves, Newspaper, or Copybook Paper Associated With Significant Reduction in Lung Function in Vanuatu
Weitz CA; Olszowy KM; Dancause KN; Sun C; Pomer A; Silverman H; Lee G; Tarivonda L; Chan CW; Kaneko A; Lum JK; Garruto RM
Article: MALARIA JOURNAL. 2017;16(1):98
Selections, frameshift mutations, and copy number variation detected on the surf_4.1 gene in the western Kenyan Plasmodium falciparum population
Gitaka JN; Takeda M; Kimura M; Idris ZM; Chan CW; Kongere J; Yahata K; Muregi FW; Ichinose Y; Kaneko A; Kaneko O
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2017;29(2)
Ownership of consumer electronics is associated with measures of adiposity during health transition in Vanuatu
Sun C; Pomer A; Dancause KN; Chan CW; Olszowy KM; Silverman H; Lee G; Tarivonda L; Taleo G; Regenvanu R; Kaneko A; Weitz CA; Garruto RM; Lum JK
Article: EPIDEMIOLOGY AND INFECTION. 2017;145(1):41-45
Surveillance for malaria outbreak on malaria-eliminating islands in Tafea Province, Vanuatu after Tropical Cyclone Pam in 2015
Chan CW; Iata H; Yaviong J; Kalkoa M; Yamar S; Taleo G; Isozumi R; Fukui M; Aoyama F; Pomer A; Dancause KN; Kaneko A
Article: SCIENTIFIC REPORTS. 2016;6:36958
High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya
Idris ZM; Chan CW; Kongere J; Gitaka J; Logedi J; Omar A; Obonyo C; Machini BK; Isozumi R; Teramoto I; Kimura M; Kaneko A
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2016;95(5):1077-1085
Genetic Diversity and Population Structure of Plasmodium falciparum in Lake Victoria Islands, A Region of Intense Transmission
Mulenge FM; Hunja CW; Magiri E; Culleton R; Kaneko A; Aman RA
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2016;60(6):3340-3347
Little Polymorphism at the K13 Propeller Locus in Worldwide Plasmodium falciparum Populations Prior to the Introduction of Artemisinin Combination Therapies
Mita T; Culleton R; Takahashi N; Nakamura M; Tsukahara T; Hunja CW; Win ZZ; Htike WW; Marma AS; Dysoley L; Ndounga M; Dzodzomenyo M; Akhwale WS; Kobayashi J; Uemura H; Kaneko A; Hombhanje F; Ferreira MU; Bjorkman A; Endo H; Ohashi J
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2015;27(6):832-844
Impact of Modernization on Adult Body Composition on Five Islands of Varying Economic Development in Vanuatu
Olszowy KM; Pomer A; Dancause KN; Sun C; Silverman H; Lee G; Chan CW; Tarivonda L; Regenvanu R; Kaneko A; Weitz CA; Lum JK; Garruto RM
Article: MALARIA JOURNAL. 2015;14:291
A prescription for sustaining community engagement in malaria elimination on Aneityum Island, Vanuatu: an application of Health Empowerment Theory
Watanabe N; Kaneko A; Yamar S; Taleo G; Tanihata T; Lum JK; Larson PS; Shearer NBC
Article: PARASITOLOGY INTERNATIONAL. 2015;64(3):304-308
Improved detection of malaria cases in island settings of Vanuatu and Kenya by PCR that targets the Plasmodium mitochondrial cytochrome c oxidase III (cox3) gene
Isozumi R; Fukui M; Kaneko A; Chan CW; Kawamoto F; Kimura M
Article: VACCINE. 2015;33(16):1901-1908
Plasmodium vivax gametocyte proteins, Pvs48/45 and Pvs47, induce transmission-reducing antibodies by DNA immunization
Tachibana M; Suwanabun N; Kaneko O; Iriko H; Otsuki H; Sattabongkot J; Kaneko A; Herrera S; Torii M; Tsuboi T
Article: EMERGING INFECTIOUS DISEASES. 2015;21(3):490-492
Novel Mutations in K13 Propeller Gene of Artemisinin-Resistant Plasmodium falciparum
Isozumi R; Uemura H; Kimata I; Ichinose Y; Logedi J; Omar AH; Kaneko A
Article: PLOS ONE. 2015;10(3):e0119475
Plasmodium vivax and Plasmodium falciparum at the Crossroads of Exchange among Islands in Vanuatu: Implications for Malaria Elimination Strategies
Chan CW; Sakihama N; Tachibana S-I; Idris ZM; Lum JK; Tanabe K; Kaneko A
Article: MALARIA JOURNAL. 2014;13:441
Determinants of the use of insecticide-treated bed nets on islands of pre- and post-malaria elimination: an application of the health belief model in Vanuatu
Watanabe N; Kaneko A; Yamar S; Leodoro H; Taleo G; Tanihata T; Lum JK; Larson PS
Article: INFECTION, GENETICS AND EVOLUTION. 2014;24:111-115
Single nucleotide polymorphisms in Plasmodium falciparum V type H⁺ pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms
Jovel IT; Ferreira PE; Veiga MI; Malmberg M; Martensson A; Kaneko A; Zakeri S; Murillo C; Nosten F; Bjorkman A; Ursing J
Article: INFECTION AND IMMUNITY. 2014;82(1):243-252
Characteristic Age Distribution of Plasmodium vivax Infections after Malaria Elimination on Aneityum Island, Vanuatu
Kaneko A; Chaves LF; Taleo G; Kalkoa M; Isozumi R; Wickremasinghe R; Perlmann H; Takeo S; Tsuboi T; Tachibana S-I; Kimura M; Bjoerkman A; Troye-Blomberg M; Tanabe K; Drakeley C
Article: PARASITOLOGY. 2013;140(5):580-586
When they don't bite, we smell money: understanding malaria bednet misuse
Honjo K; Chaves LF; Satake A; Kaneko A; Minakawa N
Article: DRUG METABOLISM AND PHARMACOKINETICS. 2013;28(6):519-521
Frequency of the Functionally Relevant Aryl Hydrocarbon Receptor Repressor (AhRR) Pro185Ala SNP in Papua New Guinea
Cavaco I; Hombhanje FW; Gil JP; Kaneko A
Article: OBESITY. 2013;21(1):E98-E104
Behavioral Risk Factors for Obesity During Health Transition in Vanuatu, South Pacific
Dancause KN; Vilar M; Wilson M; Soloway LE; DeHuff C; Chan C; Tarivonda L; Regenvanu R; Kaneko A; Lum JK; Garruto RM
Article: MOLECULAR BIOLOGY AND EVOLUTION (MBE). 2012;29(9):2095-2099
The Plasmodium Apicoplast Genome: Conserved Structure and Close Relationship of P. ovale to Rodent Malaria Parasites
Arisue N; Hashimoto T; Mitsui H; Palacpac NMQ; Kaneko A; Kawai S; Hasegawa M; Tanabe K; Horii T
Article: MALARIA JOURNAL. 2012;11:92
Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt
Takahashi N; Tanabe K; Tsukahara T; Dzodzomenyo M; Dysoley L; Khamlome B; Sattabongkot J; Nakamura M; Sakurai M; Kobayashi J; Kaneko A; Endo H; Hombhanje F; Tsuboi T; Mita T
Article: VACCINE. 2012;30(9):1583-1593
Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA5
Tanabe K; Arisue N; Palacpac NMQ; Yagi M; Tougan T; Honma H; Ferreira MU; Farnert A; Bjorkman A; Kaneko A; Nakamura M; Hirayama K; Mita T; Horii T
Article: PUBLIC HEALTH NUTRITION. 2012;15(1):158-166
Patterns of childhood and adolescent overweight and obesity during health transition in Vanuatu
Dancause KN; Vilar M; Chan C; DeHuff C; Wilson M; Soloway LE; Tarivonda L; Regenvanu R; Kaneko A; Garruto RM; Lum JK
Article: VACCINE. 2011;29(26):4308-4315
Worldwide sequence conservation of transmission-blocking vaccine candidate Pvs230 in Plasmodium vivax
Doi M; Tanabe K; Tachibana S-L; Hamai M; Tachibana M; Mita T; Yagi M; Zeyrek FY; Ferreira MU; Ohmae H; Kaneko A; Randrianarivelojosia M; Sattabongkot J; Cao Y-M; Horii T; Torii M; Tsuboi T
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2011;23(3):366-376
Behavioral Changes Associated with Economic Development in the South Pacific: Health Transition in Vanuatu
Dancause KN; Dehuff C; Soloway LE; Vilar M; Chan C; Wilson M; Tarivonda L; Regenvanu R; Kaneko A; Garruto RM; Lum JK
Article: TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE. 2011;105(4):226-231
Spleen rates in children: an old and new surveillance tool for malaria elimination initiatives in island settings
Fernando Chaves L; Taleo G; Kalkoa M; Kaneko A
Article: PLOS ONE. 2011;6(3):e17775
Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species
Arisue N; Kawai S; Hirai M; Palacpac NMQ; Jia M; Kaneko A; Tanabe K; Horii T
Article: PLOS ONE. 2011;6(9):e23875
PfMDR1: Mechanisms of Transport Modulation by Functional Polymorphisms
Ferreira PE; Holmgren G; Veiga MI; Uhlen P; Kaneko A; Gil JP
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2011;55(1):94-100
Spontaneous Mutations in the Plasmodium falciparum Sarcoplasmic/Endoplasmic Reticulum Ca²⁺-ATPase (PfATP6) Gene among Geographically Widespread Parasite Populations Unexposed to Artemisinin-Based Combination Therapies
Tanabe K; Zakeri S; Palacpac NMQ; Afsharpad M; Randrianarivelojosia M; Kaneko A; Marma ASP; Horii T; Mita T
Article: PLOS ONE. 2011;6(12):e29137
The Origins of African Plasmodium vivax; Insights from Mitochondrial Genome Sequencing
Culleton R; Coban C; Zeyrek FY; Cravo P; Kaneko A; Randrianarivelojosia M; Andrianaranjaka V; Kano S; Farnert A; Arez AP; Sharp PM; Carter R; Tanabe K
Article: CURRENT BIOLOGY. 2010;20(14):1283-1289
Plasmodium falciparum Accompanied the Human Expansion out of Africa
Tanabe K; Mita T; Jombart T; Eriksson A; Horibe S; Palacpac N; Ranford-Cartwright L; Sawai H; Sakihama N; Ohmae H; Nakamura M; Ferreira MU; Escalante AA; Prugnolle F; Bjorkman A; Farnert A; Kaneko A; Horii T; Manica A; Kishino H; Balloux F
Article: JOURNAL OF INFECTIOUS DISEASES. 2009;200(9):1456-1464
Plasmodium falciparum Multidrug Resistance Protein 1 and Artemisinin-Based Combination Therapy in Africa
Dahlstrom S; Ferreira PE; Veiga MI; Sedighi N; Wiklund L; Martensson A; Farnert A; Sisowath C; Osorio L; Darban H; Andersson B; Kaneko A; Conseil G; Bjorkman A; Gil JP
Article: ECOLOGY. 2009;90(9):2414-2425
Random, top-down, or bottom-up coexistence of parasites: malaria population dynamics in multi-parasitic settings
Chaves LF; Kaneko A; Pascual M
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2009;63(2):252-255
Indigenous evolution of Plasmodium falciparum pyrimethamine resistance multiple times in Africa
Mita T; Tanabe K; Takahashi N; Culleton R; Ndounga M; Dzodzomenyo M; Akhwale WS; Kaneko A; Kobayakawa T
Article: MALARIA JOURNAL. 2008;7:174
Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing
Culleton RL; Mita T; Ndounga M; Unger H; Cravo PVL; Paganotti GM; Takahashi N; Kaneko A; Eto H; Tinto H; Karema C; D'Alessandro U; do Rosario V; Kobayakawa T; Ntoumi F; Carter R; Tanabe K
Article: MALARIA JOURNAL. 2008;7:100
Malaria transmission pattern resilience to climatic variability is mediated by insecticide-treated nets
Chaves LF; Kaneko A; Taleo G; Pascual M; Wilson ML
Article: ACTA TROPICA. 2008;106(3):207-212
Changing patterns of forest malaria among the mobile adult male population in Chumkiri District, Cambodia
Dysoley L; Kaneko A; Eto H; Mita T; Socheat D; Borkman A; Kobayakawa T
Article: INFECTION, GENETICS AND EVOLUTION. 2008;8(3):340-345
Diversity of the sarco/endoplasmic reticulum Ca²⁺-ATPase orthologue of Plasmodium falciparum (PfATP6)
Dahlstrom S; Veiga MI; Ferreira P; Martensson A; Kaneko A; Andersson B; Bjorkman A; Gil JP
Article: JOURNAL OF HUMAN GENETICS. 2008;53(8):698-708
Reconstructing the origin of the lapita cultural complex: MtDNA analyses of east sepik province, PNG
Vilar MG; Kaneko A; Hombhanje FW; Tsukahara T; Hwaihwanje I; Lum JK
Article: PLOS MEDICINE. 2007;4(11):e309-1790
Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar
Bhattarai A; Ali AS; Kachur SP; Martensson A; Abbas AK; Khatib R; Al-Mafazy A-W; Ramsan M; Rotllant G; Gerstenmaier JF; Molteni F; Abdulla S; Montgomery SM; Kaneko A; Bjorkman A
Article: JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. 2007;34(5):669-686
Population pharmacokinetics of amodiaquine and desethylamodiaquine in pediatric patients with uncomplicated falciparum malaria
Hietala SF; Bhattarai A; Msellem M; Roshammar D; Ali AS; Stromberg J; Hombhanje FW; Kaneko A; Bjorkman A; Ashton M
Article: ACTA TROPICA. 2007;103(2):102-107
Genetic diversity and gene flow of humans, Plasmodium falciparum, and Anopheles farauti s.s. of Vanuatu:: Inferred malaria dispersal and implications for malaria control
Lum JK; Kaneko A; Taleo G; Amos M; Reiff DM
Article: JOURNAL OF MEDICAL ENTOMOLOGY. 2007;44(4):601-607
Population structure and gene flow of Anopheles farauti s.s. (Diptera: Culicidae) among ten sites on five islands of Vanuatu:: Implications for malaria control
Reiff DM; Kaneko A; Taleo G; Amos M; Lum JK
Article: ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY. 2007;101(4):281-295
Effect of artesunate plus sulfadoxine-pyrimethamine on haematological recovery and anaemia, in Kenyan children with uncomplicated, Plasmodium falciparum malaria
Obonyo CO; Taylor W; Ekvall H; Kaneko A; Ter Kuile F; Olliaro P; Bjorkman A; Oloo AJ
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2007;51(3):1071-1077
Independent evolution of pyrimethamine resistance in Plasmodium falciparum isolates in melanesia
Mita T; Tanabe K; Takahashi N; Tsukahara T; Eto H; Dysoley L; Ohmae H; Kita K; Krudsood S; Looareesuwan S; Kaneko A; Bjorkman A; Kobayakawa T
Article: INFECTION, GENETICS AND EVOLUTION. 2006;6(6):447-452
Rapid selection of dhfr mutant allele in Plasmodium falciparum isolates after the introduction of sulfadoxine/pyrimethamine in combination with 4-aminoquinolines in Papua New Guinea
Mita T; Kaneko A; Hwaihwanje I; Tsukahara T; Takahashi N; Osawa H; Tanabe K; Kobayakawa T; Bjorkman A
Article: ACTA TROPICA. 2006;99(1):15-22
Flashback to the 1960s:: Utility of archived sera to explore the origin and evolution of Plasmodium falciparum chloroquine resistance in the Pacific
Chan CW; Lynch D; Spathis R; Hombhanje FW; Kaneko A; Garruto RM; Lum JK
Article: ACTA TROPICA. 2006;98(2):137-144
Role of pfmdr1 mutations on chloroquine resistance in Plasmodium falciparum isolates with pfcrt K76T from Papua New Guinea
Mita T; Kaneko A; Hombhanje F; Hwaihwanje O; Takahashi N; Osawa H; Tsukahara T; Masta A; Lum JK; Kobayakawa T; Ishizaki T; Björkman A
Article: NATURE GENETICS. 2006;38(3):324-330
A SNP in the ABCC11 gene is the determinant of human earwax type
Yoshiura K; Kinoshita A; Ishida T; Ninokata A; Ishikawa T; Kaname T; Bannai M; Tokunaga K; Sonoda S; Komaki R; Ihara M; Saenko VA; Alipov GK; Sekine I; Komatsu K; Takahashi H; Nakashima M; Sosonkina N; Mapendano CK; Ghadami M; Nomura M; Liang DS; Miwa N; Kim DK; Garidkhuu A; Natsume N; Ohta T; Tomita H; Kaneko A; Kikuchi M; Russomando G; Hirayama K; Ishibashi M; Takahashi A; Saitou N; Murray JC; Saito S; Nakamura Y; Niikawa N
Article: JAPANESE JOURNAL OF INFECTIOUS DISEASES. 2006;59(1):63-65
Seroprevalence of human herpesvirus 8 in the Vanuatu islands in eastern Melanesia
Satoh M; Kaneko A; Kokaze A; Katano H; Sata T
Article: JOURNAL OF HUMAN GENETICS. 2006;51(3):244-248
Austronesian origin of the 27-bp deletion of the erythrocyte band 3 gene in East Sepik, Papua New Guinea inferred from mtDNA analysis
Tsukahara T; Hombhanje FW; Lum JK; Hwaihwanje H; Masta A; Kaneko A; Kobayakawa T
Article: PARASITOLOGY INTERNATIONAL. 2005;54(2):109-118
The involvement of neutrophils in the resistance to Leishmania major infection in susceptible but not in resistant mice
Chen L; Zhang ZH; Watanabe T; Yamashita T; Kobayakawa T; Kaneko A; Fujiwara H; Sendo F
Article: TROPICAL MEDICINE AND INTERNATIONAL HEALTH. 2005;10(6):544-549
Associations between frequencies of a susceptible TNF-α promoter allele and protective α-thalassaemias and malaria parasite incidence in Vanuatu
Ubalee R; Tsukahara T; Kikuchi M; Lum JK; Dzodzomenyo M; Kaneko A; Hirayama K
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2005;61(1):15-18
CYP2C8 polymorphism frequencies among malaria patients in Zanzibar
Cavaco I; Strömberg-Nörklit J; Kaneko A; Msellem MI; Dahoma M; Ribeiro VL; Bjorkman A; Gil JP
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2005;59(3):298-301
The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria
Hombhanje FW; Hwaihwanje I; Tsukahara T; Saruwatari J; Nakagawa M; Osawa H; Paniu MM; Takahashi N; Lum JK; Aumora B; Masta A; Sapuri M; Kobayakawa T; Kaneko A; Ishizaki T
Article: ACTA TROPICA. 2004;91(2):167-175
Anemia and malaria at different altitudes in the western highlands of Kenya
Akhwale WS; Lum JK; Kaneko A; Eto H; Obonyo C; Björkman A; Kobayakawa T
Article: MOLECULAR AND BIOCHEMICAL PARASITOLOGY. 2004;135(1):159-163
Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi
Mita T; Kaneko A; Lum JK; Zungu IL; Tsukahara T; Eto H; Kobayakawa T; Björkman A; Tanabe K
Article: ACTA TROPICA. 2004;90(2):181-185
Malaria dispersal among islands:: human mediated Plasmodium falciparum gene flow in Vanuatu, Melanesia
Lum JK; Kaneko A; Tanabe K; Takahashi N; Björkman A; Kobayakawa T
Article: SCIENCE. 2004;303(5657):493
Stable SNPs in malaria antigen genes in isolated populations
Tanabe K; Sakihama N; Kaneko A
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2003;68(4):413-415
Recovery of chloroquine sensitivity and low prevalence of the Plasmodium falciparum chloroquine resistance transporter gene mutation K76T following the discontinuance of chloroquine use in Malawi
Mita T; Kaneko A; Lum JK; Bwijo B; Takechi N; Zungu IL; Tsukahara T; Tanabe K; Kobayakawa T; Björkman A
Article: ACTA TROPICA. 2003;85(3):363-373
High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi
Bwijo B; Kaneko A; Takechi M; Zungu IL; Moriyama Y; Lum JK; Tsukahara T; Mita T; Takahashi N; Bergqvist Y; Björkman J; Kobayakawa T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(25):16348-16353
Mosaic organization and heterogeneity in frequency of allelic recombination of the Plasmodium vivax merozoite surface protein-1 locus
Putaporntip C; Jongwutiwes S; Sakihama N; Ferreira MU; Kho WG; Kaneko A; Kanbara H; Hattori T; Tanabe K
Article: CHROMATOGRAPHIA. 2002;55(1-2):5-12
Automated solid-phase extraction for determination of amodiaquine, chloroquine and metabolites in capillary blood on sampling paper by liquid chromatography
Lindegårdh N; Forslund M; Green MD; Kaneko A; Bergqvist Y
Article: GENE. 2001;279(1):41-48
Limited recombination events in merozoite surface protein-1 alleles of Plasmodium falciparum on islands
Sakihama N; Kaneko A; Hattori T; Tanabe K
Article: EXPERIMENTAL PARASITOLOGY. 2001;97(1):50-54
Long PCR amplification of Plasmodium falciparum DNA extracted from filter paper blots
Sakihama N; Mitamura T; Kaneko A; Horii T; Tanabe K
Article: THE LANCET. 2000;356(9241):1560-1564
Malaria eradication on islands
Kaneko A; Taleo G; Kalkoa M; Yamar S; Kobayakawa T; Björkman A
Article: PHARMACOGENETICS AND GENOMICS. 1999;9(5):581-590
High and variable frequencies of CYP2C19 mutations:: medical consequences of poor drug metabolism in Vanuatu and other Pacific islands
Kaneko A; Lum JK; Yaviong J; Takahashi N; Ishizaki T; Bertilsson L; Kobayakawa T; Björkman A
Article: ACTA TROPICA. 1999;73(2):109-119
CD4⁺ and/or γδ⁺ T cells in the liver spontaneously produce IL-4 in vitro during the early phase of Leishmania major infection in susceptible BALB/c mice
Yamashita T; Miyata H; Miyaji C; Watanabe H; Abo T; Kobayakawa T; Kaneko A; Sendo F
Article: PHARMACOGENETICS AND GENOMICS. 1999;9(3):317-326
Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations
Kaneko A; Bergqvist Y; Taleo G; Kobayakawa T; Ishizaki T; Björkman A
Article: JOURNAL OF CHROMATOGRAPHY B: ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 1998;719(1-2):141-149
Improved method for the simultaneous determination of proguanil and its metabolites by high-performance liquid chromatography and solid-phase extraction of 100-μ1 capillary blood samples dried on sampling paper
Bergqvist Y; Funding L; Kaneko A; Krysén B; Leek T
Article: ACTA TROPICA. 1998;70(3):285-302
Malaria epidemiology, glucose 6-phosphate dehydrogenase deficiency and human settlement in the Vanuatu Archipelago
Kaneko A; Taleo G; Kalkoa M; Yaviong J; Reeve PA; Ganczakowski M; Shirakawa C; Palmer K; Kobayakawa T; Björkman A
Article: THE LANCET. 1997;349(9056):921-922
High frequencies of CYP2C19 mutations and poor metabolism of proguanil in Vanuatu
Kaneko A; Kaneko O; Taleo G; Bjorkman A; Kobayakawa T
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;56(1):294-301
MULTIPLE GLUCOSE-6-PHOSPHATE DEHYDROGENASE-DEFICIENT VARIANTS CORRELATE WITH MALARIA ENDEMICITY IN THE VANUATU ARCHIPELAGO (SOUTHWESTERN PACIFIC)
GANCZAKOWSKI M; TOWN M; BOWDEN DK; VULLIAMY TJ; KANEKO A; CLEGG JB; WEATHERALL DJ; LUZZATTO L
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All other publications

Review: BMC MEDICINE. 2022;20(1):350
Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data
Stepniewska K; Allen EN; Humphreys GS; Poirot E; Craig E; Kennon K; Yilma D; Bousema T; Guerin PJ; White NJ; Price RN; Raman J; Martensson A; Mwaiswelo RO; Bancone G; Bastiaens GJH; Bjorkman A; Brown JM; D'Alessandro U; Dicko AA; El-Sayed B; Elzaki S-E; Eziefula AC; Goncalves BP; Hamid MMA; Kaneko A; Kariuki S; Khan W; Kwambai TK; Ley B; Ngasala BE; Nosten F; Okebe J; Samuels AM; Smit MR; Stone WJR; Sutanto I; Ter Kuile F; Tine RC; Tiono AB; Drakeley CJ; Gosling R; Stergachis A; Barnes KI; Chen I
Letter: JOURNAL OF DERMATOLOGY. 2015;42(8):840-841
Repeated myiasis in a female vulvar squamous cell carcinoma caused by Lucilia sericata and Sarcophaga crassipalpis
Hiraoka H; Ozawa T; Sowa-Osako J; Ichimura T; Kimata-Teramoto I; Isozumi R; Kaneko A; Tsuruta D
Editorial comment: CLINICAL INFECTIOUS DISEASES. 2012;54(8):1145-1147
Iron Deficiency and Severe Plasmodium falciparum Malaria
Awah NW; Kaneko A
Editorial comment: ACTA TROPICA. 2010;114(3):129-130
Malaria research-Diversity and control: A Sweden-Japan joint seminar Foreword
Kaneko A; Wahlgren M
Published conference paper: ACTA TROPICA. 2010;114(3):177-183
A community-directed strategy for sustainable malaria elimination on islands: Short-term MDA integrated with ITNs and robust surveillance
Kaneko A
Published conference paper: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2003;531:71-82
Malaria on islands - Human and parasite diversities and implications for malaria control in Vanuatu
Kaneko AA
Thesis / dissertation: 1999
Malaria on islands : human and parasite diversities and implications for malaria control in Vanuatu
Kaneko, Akira
Published conference paper: JOURNAL OF INFECTIOUS DISEASES. 1999;179(4):974-979
Intrinsic efficacy of proguanil against falciparum and vivax malaria independent of the metabolite cycloguanil
Kaneko A; Bergqvist Y; Takechi M; Kalkoa M; Kaneko O; Kobayakawa T; Ishizaki T; Björkman A

Employments

Professor, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2011-

Degrees and Education

Docent, Karolinska Institutet, 2004
Ph.D, Department of Medicine, Karolinska Institute, 1999
D.T.M. & H., Diploma in Tropical Medicine and Hygiene, Hygiene Faculty of Tropical Medicine, Mahidol University, 1984
M.D., Hirosaki University School of Medicine, 1982

Distinction and awards

The TROPMED Outstanding Alumni Award, Faculty of Tropical Medicine, Mahidol University, 2018
Tropical Medicine Award, , Japanese Society of Tropical Medicine, 2016
Senior Researcher Position grant, 2010 – 2016, Swedish Research Council, 2010
Hohoh Prize, Hirosaki University School of Medicine, Japan, Hirosaki University School of Medicine, Japan, 2006
Tokyo Metropolitan Medical Research Award, Japan, Tokyo Metropolitan, 2001

About me

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Degrees and Education

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