Aikaterini Motso

Selected publications

Article: CELL. 2025;188(19):5142-5156.e23
GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity
Motso A; Pelcman B; Kalinovich A; Kahlous NA; Bokhari MH; Dehvari N; Halleskog C; Waara E; de Jong J; Cheesman E; Kallenberg C; Yakala GK; Murad P; Wetterdal E; Andersson P; van Beek S; Sandström A; Alleluia DN; Talamonti E; Youhanna S; Sabatier P; Koenig C; Willems S; Kemas AM; Hutchinson DS; Ham S; Grätz L; Voss J; Marchan-Alvarez JG; Priede M; Jaunsleine K; Spura J; Kovada V; Supe L; Stoddart LA; Holliday ND; Newton PT; Pillon NJ; Schulte G; Summers RJ; Mutule I; Suna E; Olsen JV; Molenaar P; Carlsson J; Lauschke VM; Wright SC; Bengtsson T
Article: NATURE COMMUNICATIONS. 2023;14(1):6243
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
Wright SC; Motso A; Koutsilieri S; Beusch CM; Sabatier P; Berghella A; Blondel-Tepaz E; Mangenot K; Pittarokoilis I; Sismanoglou D-C; Le Gouill C; Olsen JV; Zubarev RA; Lambert NA; Hauser AS; Bouvier M; Lauschke VM

Article: ADVANCED SCIENCE. 2025;12(3):e2407572
Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention
Youhanna S; Kemas AM; Wright SC; Zhong Y; Klumpp B; Klein K; Motso A; Michel M; Ziegler N; Shang M; Sabatier P; Kannt A; Sheng H; Oliva-Vilarnau N; Buettner FA; Seashore-Ludlow B; Schreiner J; Windbergs M; Cornillet M; Bjorkstrom NK; Hulsmeier AJ; Hornemann T; Olsen JV; Wang Y; Gramignoli R; Sundstrom M; Lauschke VM
Article: MOLECULAR METABOLISM. 2024;85:101931
The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis
Talamonti E; Davegardh J; Kalinovich A; van Beek SMM; Dehvari N; Halleskog C; Bokhari HM; Hutchinson DS; Ham S; Humphrys LJ; Dijon NC; Motso A; Sandstrom A; Zacharewicz E; Mutule I; Suna E; Spura J; Ditrychova K; Stoddart LA; Holliday ND; Wright SC; Lauschke VM; Nielsen S; Scheele C; Cheesman E; Hoeks J; Molenaar P; Summers RJ; Pelcman B; Yakala GK; Bengtsson T
Article: JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 2023;145(19):10659-10668
Mass Spectrometry of RNA-Binding Proteins during Liquid-Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures
Sahin C; Motso A; Gu X; Feyrer H; Lama D; Arndt T; Rising A; Gese GV; Haellberg BM; Marklund EG; Schafer NP; Petzold K; Teilum K; Wolynes PG; Landreh M

Corrigendum: CELL. 2025;188(19):5429-5431
GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity (vol. 188, pg. 5142, 2025)
Motso A; Pelcman B; Kalinovich A; Kahlous NA; Bokhari MH; Dehvari N; Halleskog C; Waara E; de Jong J; Cheesman E; Kallenberg C; Yakala GK; Murad P; Wetterdal E; Andersson P; van Beek S; Sandstrom A; Alleluia DN; Talamonti E; Youhanna S; Sabatier P; Koenig C; Willems S; Kemas AM; Hutchinson DS; Ham S; Gratz L; Voss J; Marchan-Alvarez JG; Priede M; Jaunsleine K; Spura J; Kovada V; Supe L; Stoddart LA; Holliday ND; Newton PT; Pillon NJ; Schulte G; Summers RJ; Mutule I; Suna E; Olsen JV; Molenaar P; Carlsson J; Lauschke VM; Wright SC; Bengtsson T

Affiliated to Research, Department of Physiology and Pharmacology, Karolinska Institutet, 2025-2028