Aase Hensvold

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Articles

Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2023;52(5):460-467
The Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: predicting clinical arthritis development
van Boheemen L; Ter Wee MM; Falahee M; Filer A; Van Beers-Tas M; Finckh A; Hensvold A; Raza K; van Schaardenburg D
Article: JOURNAL OF AUTOIMMUNITY. 2023;136:103022
The human bone marrow plasma cell compartment in rheumatoid arthritis-Clonal relationships and anti-citrulline autoantibody producing cells
Hensvold A; Horuluoglu B; Sahlstrom P; Thyagarajan R; Boada JSD; Hansson M; Mathsson-Alm L; Gerstner C; Sippl N; Israelsson L; Wedin R; Steen J; Klareskog L; Rethi B; Catrina AI; Diaz-Gallo L-M; Malmstrom V; Gronwall C
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(2):164-170
Combination of Two Monoclonal Anti-Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase-4-Dependent Manner
Krishnamurthy A; Circiumaru A; Sun J; Kisten Y; Damberg P; Sakuraba K; Sandor K; Jarvoll P; Zhou T; Malmstrom V; Svensson CI; Hensvold A; Catrina AI; Klareskog L; Rethi B
Article: FRONTIERS IN MEDICINE. 2023;10:1146353
Molecular signature of methotrexate response among rheumatoid arthritis patients
Brynedal B; Yoosuf N; Ulfarsdottir TB; Ziemek D; Maciejewski M; Folkersen L; Westerlind H; Mueller M; Sahlstrom P; Jelinsky SA; Hensvold A; Padyukov L; Pomiano NV; Catrina A; Klareskog L; Berg L
Article: NATURE COMMUNICATIONS. 2022;13(1):4046
Single cell sequencing identifies clonally expanded synovial CD4⁺ T_PH cells expressing GPR56 in rheumatoid arthritis
Argyriou A; Wadsworth MH; Lendvai A; Christensen SM; Hensvold AH; Gerstner C; van Vollenhoven A; Kravarik K; Winkler A; Malmstrom V; Chemin K
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):129
Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium
Vickovic S; Schapiro D; Carlberg K; Lotstedt B; Larsson L; Hildebrandt F; Korotkova M; Hensvold AH; Catrina AI; Sorger PK; Malmstrom V; Regev A; Stahl PL
Article: FRONTIERS IN MEDICINE. 2022;9:774945
Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study
Knevel R; Knitza J; Hensvold A; Circiumaru A; Bruce T; Evans S; Maarseveen T; Maurits M; Beaart-van de Voorde L; Simon D; Kleyer A; Johannesson M; Schett G; Huizinga T; Svanteson S; Lindfors A; Klareskog L; Catrina A
Article: FRONTIERS IN MEDICINE. 2022;9:824501
Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry
Studenic P; Hensvold A; Kleyer A; van der Helm-van Mil A; Pratt AG; Sieghart D; Kroenke G; Williams R; de Souza S; Karlfeldt S; Johannesson M; Krogh NS; Klareskog L; Catrina AI
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822
Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology
Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stalesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Roennelid J; Groenwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmstroem V; Amara K; Lundberg K
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):239
The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual "window of treatment success" in RA patients
Marklein B; Jenning M; Konthur Z; Haupl T; Welzel F; Nonhoff U; Krobitsch S; Mulder DM; Koenders MI; Joshua V; Cope AP; Shlomchik MJ; Anders H-J; Burmester GR; Hensvold A; Catrina AI; Ronnelid J; Steiner G; Skriner K
Article: RMD OPEN. 2021;7(2):e001662
Tocilizumab decreases T cells but not macrophages in the synovium of patients with rheumatoid arthritis while it increases the levels of serum interleukin-6 and RANKL
Chatzidionysiou K; Circiumaru A; Rethi B; Joshua V; Engstrom M; Hensvold A; af Klint E; Catrina A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:627986
A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis
Gronwall C; Liljefors L; Bang H; Hensvold AH; Hansson M; Mathsson-Alm L; Israelsson L; Joshua V; Svard A; Stalesen R; Titcombe PJ; Steen J; Piccoli L; Sherina N; Clavel C; Svenungsson E; Gunnarsson I; Saevarsdottir S; Kastbom A; Serre G; Alfredsson L; Malmstrom V; Ronnelid J; Catrina AI; Lundberg K; Klareskog L
Article: RMD OPEN. 2020;6(2):e001278
Association between number and type of different ACPA fine specificities with lung abnormalities in early, untreated rheumatoid arthritis
Joshua V; Hensvold AH; Reynisdottir G; Hansson M; Cornillet M; Nogueira L; Serre G; Nyren S; Karimi R; Eklund A; Skold M; Grunewald J; Chatzidionysiou K; Catrina A
Article: BMC IMMUNOLOGY. 2020;21(1):27
Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis
Gerstner C; Turcinov S; Hensvold AH; Chemin K; Uchtenhagen H; Ramwadhdoebe TH; Dubnovitsky A; Kozhukh G; Ronnblom L; Kwok WW; Achour A; Catrina A; van Baarsen LGM; Malmstrom V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631
Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts
Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Gronwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wahamaa H; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2018;20(1):146
The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
Jonsson MK; Hensvold AH; Hansson M; Aga A-B; Sexton J; Mathsson-Alm L; Cornillet M; Serre G; Lillegraven S; Fevang B-TS; Catrina AI; Haavardsholm EA
Article: JOURNAL OF AUTOIMMUNITY. 2018;90:28-38
T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus
Houtman M; Shchetynsky K; Chemin K; Hensvold AH; Ramskold D; Tandre K; Eloranta M-L; Ronnblom L; Uebe S; Catrina AI; Malmstrom V; Padyukov L
Article: RMD OPEN. 2018;4(1):e000641
Initial validation and results of the Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: a EULAR project
Van Beers-Tas MH; ter Wee MM; van Tuyl LH; Maat B; Hoogland W; Hensvold AH; Catrina AI; Mosor E; Stamm TA; Finckh A; Courvoisier DS; Filer A; Sahbudin I; Stack RJ; Raza K; van Schaardenburg D
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):182
IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis
Lundstrom SL; Hensvold AH; Rutishauser D; Klareskog L; Ytterberg AJ; Zubarev RA; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):19
Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis
Shchetynsky K; Diaz-Gallo L-M; Folkersen L; Hensvold AH; Catrina AI; Berg L; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(1):119-125
How well do ACPA discriminate and predict RA in the general population: a study based on 12 590 population-representative Swedish twins
Hensvold AH; Frisell T; Magnusson PKE; Holmdahl R; Askling J; Catrina AI
Article: GENOME MEDICINE. 2016;8(1):124
High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis
Gomez-Cabrero D; Almgren M; Sjoholm LK; Hensvold AH; Ringh MV; Tryggvadottir R; Kere J; Scheynius A; Acevedo N; Reinius L; Taub MA; Montano C; Aryee MJ; Feinberg JI; Feinberg AP; Tegner J; Klareskog L; Catrina AI; Ekstrom TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(10):1891-1898
Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA
van Heemst J; Hensvold AH; Jiang X; van Steenbergen H; Klareskog L; Huizinga TWJ; van der Helm-van Mil A; Catrina AI; Toes REM; Lundberg K; van der Woude D
Article: MOLECULAR MEDICINE. 2016;22:322-328
Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study
Folkersen L; Brynedal B; Diaz-Gallo LM; Ramskold D; Shchetynsky K; Westerlind H; Sundstrom Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Ronnblom L; Brunak S; Malmstrom V; Catrina A; Moerch UGW; Klareskog L; Padyukov L; Berg L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
Krishnamurthy A; Joshua V; Hensvold AH; Jin T; Sun M; Vivar N; Ytterberg AJ; Engstrom M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jimenez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmstrom V; Klareskog L; Wahamaa H; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):239
Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate
Hensvold AH; Joshua V; Li W; Larkin M; Qureshi F; Israelsson L; Padyukov L; Lundberg K; Defranoux N; Saevarsdottir S; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(9):1772-1777
Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation
Ytterberg AJ; Joshua V; Reynisdottir G; Tarasova NK; Rutishauser D; Ossipova E; Hensvold AH; Eklund A; Skold CM; Grunewald J; Malmstrom V; Jakobsson PJ; Ronnelid J; Padyukov L; Zubarev RA; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(2):375-380
Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins
Hensvold AH; Magnusson PKE; Joshua V; Hansson M; Israelsson L; Ferreira R; Jakobsson P-J; Holmdahl R; Hammarstrom L; Malmstrom V; Askling J; Klareskog L; Catrina AI
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(1):31-39
Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis
Reynisdottir G; Karimi R; Joshua V; Olsen H; Hensvold AH; Harju A; Engstrom M; Grunewald J; Nyren S; Eklund A; Klareskog L; Skold CM; Catrina AI
Article: PLOS ONE. 2014;9(11):e113924
IgG Antibodies to Cyclic Citrullinated Peptides Exhibit Profiles Specific in Terms of IgG Subclasses, Fc-Glycans and a Fab-Peptide Sequence
Lundstrom SL; Fernandes-Cerqueira C; Ytterberg AJ; Ossipova E; Hensvold AH; Jakobsson P-J; Malmstrom V; Catrina AI; Klareskog L; Lundberg K; Zubarev RA
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(10):1822-1825
Delays in assessment of patients with rheumatoid arthritis: variations across Europe
Raza K; Stack R; Kumar K; Filer A; Detert J; Bastian H; Burmester GR; Sidiropoulos P; Kteniadaki E; Repa A; Saxne T; Turesson C; Mann H; Vencovsky J; Catrina A; Chatzidionysiou A; Hensvold A; Rantapaa-Dahlqvist S; Binder A; Machold K; Kwiakowska B; Ciurea A; Tamborrini G; Kyburz D; Buckley CD
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Letter: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):724-726
Divergent and dominant anti-inflammatory effects of patient-derived anticitrullinated protein antibodies (ACPA) in arthritis development
Raposo B; Afonso M; Israelsson L; Waehaemaa H; Stalesen R; Wermeling F; Hensvold AH; Groenwall C; Rethi B; Klareskog L; Malmstrom V
Corrigendum: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):255
The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual " window of treatment success" in RA patients (vol 23, 239, 2021)
Marklein B; Jenning M; Konthur Z; Haeupl T; Welzel F; Nonhoff U; Krobitsch S; Mulder DM; Koenders MI; Joshua V; Cope AP; Shlomchik MJ; Anders H-J; Burmester GR; Hensvold A; Catrina AI; Roennelid J; Steiner G; Skriner K
Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(8):1921-1933
Towards prevention of autoimmune diseases: The example of rheumatoid arthritis
Hensvold A; Klareskog L
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(6):1309
Anca Catrina 1971-2021 Obituary
Klareskog L; Rethi B; Hensvold A; Wahamaa H; Jakobsson P-J
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(6):e30
Challenging judgement of a low-positive ACPA test in the context of individuals at risk of RA
Hensvold AH; Catrina AI
Thesis / dissertation: 2016
Studies on the role of anti-citrullinated protein antibodies in rheumatoid arthritis
Hensvold, Aase Eline Haj

Employments

Affiliated to Research, Department of Medicine, Karolinska Institutet, 2023-2025

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2016

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