Ethic review of animal experiments
In Sweden, animal experiments must be evaluated and approved by a regional ethical committee. An experiment cannot begin until an ethical committee has approved it. It is the research group leader/project director who can apply for ethical evaluation of animal experiments.
From 2016, it is mandatory to use the Swedish Board of Agriculture's e-service to apply for ethical approval.
From January 16th 2017, it is also mandatory to use the e-service for supplementary applications.
Login to the e-service (link to Jordbruksverket.se, in Swedish)
You log in to the services using an electronic ID.
How to apply
The departments at KI may have different routines concerning ethics applications. Below is a general description of the procedure.
- Contact the designated superintendent at your animal facility to let them know you are planning to submit an application for ethical evaluation of an animal experiment.
- Plan your experiment in consultation with the designated superintendent, the designated veterinarian and the technical staff at all animal facilities involved in the experiment (also at facilities where only a minor part of the experiment will be carried out). Put together an application. The consultation is coordinated by the designated superintendent.
- Revise your application according to the consultation, so the designated superintendent later on can approve it.
- Login to the e-service and apply. It is you who are research group leader/project director that must apply. The designated superintendent must approve the application. A message will be sent via email to the designated superintendent when there is an application to review.
- An application fee must be paid to the Swedish Board of Agriculture. When you pay by credit card, or order an invoice, you will receive an order number. The order number needs to be included on the application form. The invoice itself does not have to be paid at the time you submit your application to the ethical committee. Application fee for ethical evaluation (page in Swedish at Jordbruksverket.se)
- The Stockholm ethical committee sends out an email to everyone who has submitted an application. The mail is usually sent within 2 weeks and contains general information and, when applicable, remarks specific to the application. An applicant who has not received such an e-mail, even though three weeks have passed since the application was sent, shall control the application in the online services. There can be a problem due to a technical issue or the application may not have been completed.
- If you are unable to obtain an electronic ID, you can contact the Swedish Board of Agriculture and apply for an exemption.
- One (1) ethical permit can never apply to facilities belonging to different facility license holders (that is for example two authorities: KI and SLL, or two universities. There is a new global license that applies to all animal facilities at KI. Therefore, contact Comparative Medicine (firstname.lastname@example.org) if you are planning a project that includes several facilities within KI, to find out which license you can use in your application. This applies to both breeding and use. Note: as described above, the global license is only for facilities at KI and not for facilities under the governance of SLL.
- Education in the electronic application system has been offered in 2015. Contact your designated superintendent if you have questions about this.
- If the application involves several designated superintendents one must be selected in the application system and the others sign a separate attachment. Go to form for signatures by several designated superintendents.
When the permit is approved
After approval the permit should be kept at the facility. Comparative Medicine recommends a consultation number two at the facility in connection to the project start. The designated supperintendent is responsible for the consultation, which involves both veterinarian and technicians. The consultation can be kept simple and short, but may also require follow-up meetings. The aim is to carry out the experiment as efficiently as possible. At Comparative Medicine's facilities it is required that you enclose: animal project plan, checklist laboratory safety risk inventory and, if necessary, a risk assessment form BARA for biosafety. In some cases there is a requirement for a retrospective evaluation; most often in cases regarding experiments with considerable severity or of a particular interest. Read more about this under Ethical Committees.
Approved applications may be supplemented. The Swedish Board of Agriculture may charge an application fee when submitting a supplementary application.
From January 16th 2017, it is manadatory to use the e-service also for supplementary applications.