Ethic review of animal experiments
In Sweden, animal experiments must be evaluated and approved by a regional ethical committee. An experiment cannot begin until an ethical committee has approved it. It is the research group leader/project director who can apply for ethical evaluation of animal experiments.
It is mandatory to use the Swedish Board of Agriculture's e-service to apply for ethical approval or supplementary applications.
From July 15th, 2018, supplementary applications that does not have a negative impact on the animal, also be sent to the local Animal Welfare Body (for more information, see 5 kap 4§ i L150 (SJVFS 2017:40)).
Login to the e-service (link to Jordbruksverket.se, in Swedish)
You log in to the services using an electronic ID.
How to apply
The departments at KI may have different routines concerning ethics applications. Below is a general description of the procedure.
- Contact the designated expert at your animal facility to inform that you are planning to submit an application for ethical evaluation of an animal experiment.
- Plan your experiment and write a draft (only for the consultation, the application must be done in the e-service). The draft shall be done in consultation with the designated veterinarian, the designated expert and a representative of the technical staff at the animal facility/facilities that is involved in the experiment (also at facilities where only a minor part of the experiment will be carried out). Put together an application. The consultation is coordinated by the designated expert.
- Revise your application according to the consultation. In order to facilitate the process in the Ethics Committee, it is recommended that you let the expert and the veterinarian read the application one last time.
- Login to the e-service and apply. It is you who are research group leader/project director that must apply. The designated superintendent must approve the application. If you as a research group leader does not consult the veterinarian and the expert before submitting your ethical application, you may be denied by the permit holder at KI to conduct research at KI's animal facilities.
- An application fee must be paid to the Swedish Board of Agriculture. You pay the fee in the Swedish Board of Agriculture’s web store. When you pay by credit card, or order an invoice, you will receive an order number. The order number needs to be included in the application form. The invoice itself does not have to be paid at the time you submit your application to the ethical committee. Application fee for ethical evaluation (page in Swedish at Jordbruksverket.se)
- The Stockholm ethical committee sends out an email to everyone who has submitted an application. The mail is usually sent within 2 weeks and contains general information and, when applicable, remarks specific to the application. An applicant who has not received such an e-mail, even though three weeks have passed since the application was sent, shall control the application in the online services. There can be a problem due to a technical issue or the application may not have been completed.
- If you are unable to obtain an electronic ID, you can contact the Swedish Board of Agriculture and apply for an exemption.
- One (1) ethical permit can never apply to facilities belonging to different facility license holders (that is for example two authorities: KI and SLL, or two universities. There is a new global license that applies to all animal facilities at KI. Therefore, contact Comparative Medicine (firstname.lastname@example.org) if you are planning a project that includes several facilities within KI, to find out which license you can use in your application. This applies to both breeding and use. Note: as described above, the global license is only for facilities at KI and not for facilities under the governance of SLL.
When the permit is approved
After approval the permit should be kept at the facility. Comparative Medicine recommends a consultation number two at the facility in connection to the project start. The designated expert is responsible for the consultation, which involves both veterinarian, animal technicians and all members in the research group. The consultation can be kept simple and short, but may also require follow-up meetings. The aim is to carry out the experiment as efficiently as possible. At Comparative Medicine's facilities it is required that you enclose: animal project plan, checklist laboratory safety risk inventory and, if necessary, a risk assessment form BARA for biosafety. In some cases there is a requirement for a retrospective evaluation; most often in cases regarding experiments with considerable severity or of a particular interest. Read more about this under Ethical Committees.
Approved applications may be supplemented. The Swedish Board of Agriculture may charge an application fee when submitting a supplementary application.
Supplementary application, that does not affect the animal
Regarding supplementary applications without increased suffering of the animal may the supplement be applied for at the local Animal Welfare Body. Please see KM’s web page Animal Welfare Body, and send your application to email@example.com.