Department of Cell and Molecular Biology
The Department of Cell and Molecular Biology at Karolinska Institutet is a nationally leading academic research center of high international standard where science comes first and foremost. CMB researchers publish regularly in the best international science journals, a result of a long-term in-house culture that promotes real impact and key breakthroughs.
CMB News
A new technology to see tubes in 3D in mice shows how the liver can recover in Alagille syndrome
A new technology to see tubes in 3D in mice shows how the liver can recover in Alagille syndrome
We developed a new method, independent of antibodies or microscopes, to visualize multiple vessels at the same time in a mouse model for a human disease known as Alagille syndrome.
New article in Nucleic Acids Research about aberrant splicing in neuroblastoma
New article in Nucleic Acids Research about aberrant splicing in neuroblastoma
Johan Holmberg and Yao Shi's study suggests that splicing-dependent RNA-fusions represent an alternative mechanism, distinct from amino acid changing mutations, through which altered gene products with an oncogenic potential can be generated in neuroblastoma and that the spliceosome represents a possible targetable aspect of this disease.
Professor Kenneth Chien about Moderna and the COVID-19-vaccine
Professor Kenneth Chien about Moderna and the COVID-19-vaccine
The success of the mRNA-based vaccines is a boost for the entire mRNA field and can lead to new treatments for completely different diseases. This is the view of Kenneth Chien, professor at Karolinska Institutet and co-founder of Moderna, one of the companies that has now developed a vaccine against COVID-19.
New small antibodies show promising effects against COVID-19 infection
New small antibodies show promising effects against COVID-19 infection
Researchers at Karolinska Institutet have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells. The research study, published in Science, shows that a combined nanobody had a particularly good effect – even if the virus mutated. According to the researchers, the nanobodies have the potential to be developed into a treatment for COVID-19.
New core facility offers world class imaging technique
New core facility offers world class imaging technique
In the basement of Wargentin House on Solna campus there are several cryo-electron microscopes of the latest models, that can be used by both KI researchers and external customers. Read an interview with Martin Hällberg, director of the new 3D-EM facility.