Department of Cell and Molecular Biology
The Department of Cell and Molecular Biology at Karolinska Institutet is a nationally leading academic research center of high international standard where science comes first and foremost. CMB researchers publish regularly in the best international science journals, a result of a long-term in-house culture that promotes real impact and key breakthroughs.
CMB News
New technique to manipulate gene expression and study genetic diseases
New technique to manipulate gene expression and study genetic diseases
Emma Andersson, senior researcher at the department of Cell and Molecular Biology, and Karin Mangold, PhD student, have recently published an article in Cell Reports Methods in which they developed a new technique to reduce the use of mice and to get faster results.
Mitochondrial ribosome assembly in 3D
Mitochondrial ribosome assembly in 3D
In a study published in Nature Communications, researchers at Karolinska Institutet provide insight into the sequence of events leading to formation of functional mitoribosomes and sheds light on the mechanism of action of nine mitoribosome assembly factors involved in this process. The results may help yield novel opportunities for diagnosis and therapeutic intervention for mitochondrial diseases as well as cancer or diabetes.
New article in Nature Metabolism about an in vivo drug discovery for β-cell proliferation in diabetes
New article in Nature Metabolism about an in vivo drug discovery for β-cell proliferation in diabetes
In a study published in Nature Metabolism, researchers at the department of Cell and Molecular Biology developed a novel technique to identify small molecules that can make insulin-producing β-cells divide.
Single cell sequencing unravels molecular identity of rare renal cell types
Single cell sequencing unravels molecular identity of rare renal cell types
Jaakko Patrakka and his research group at the Department of Laboratory Medicine have together with Professor Rickard Sandberg's group at the Department of Cell and Molecular Biology got a publication accepted in Nature Communications about single cell sequencing unravels molecular identity of rare renal cell types.
A new technology to see tubes in 3D in mice shows how the liver can recover in Alagille syndrome
A new technology to see tubes in 3D in mice shows how the liver can recover in Alagille syndrome
We developed a new method, independent of antibodies or microscopes, to visualize multiple vessels at the same time in a mouse model for a human disease known as Alagille syndrome.
Professor Kenneth Chien about Moderna and the COVID-19-vaccine
Professor Kenneth Chien about Moderna and the COVID-19-vaccine
The success of the mRNA-based vaccines is a boost for the entire mRNA field and can lead to new treatments for completely different diseases. This is the view of Kenneth Chien, professor at Karolinska Institutet and co-founder of Moderna, one of the companies that has now developed a vaccine against COVID-19.