Marcela Franco

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CANCER RESEARCH COMMUNICATIONS. 2022;2(3):182-201

MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner.

Castell A; Yan Q; Fawkner K; Bazzar W; Zhang F; Wickström M; Alzrigat M; Franco M; Krona C; Cameron DP; Dyberg C; Olsen TK; Verschut V; Schmidt L; Lim SY; Mahmoud L; Hydbring P; Lehmann S; Baranello L; Nelander S; Johnsen JI; Larsson L-G
Article: ELIFE. 2020;9:e57894

PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer.

Brunner A; Suryo Rahmanto A; Johansson H; Franco M; Viiliäinen J; Gazi M; Frings O; Fredlund E; Spruck C; Lehtiö J; Rantala JK; Larsson L-G; Sangfelt O
Article: SCIENTIFIC REPORTS. 2019;9(1):2379

Prediction of response to anti-cancer drugs becomes robust via network integration of molecular data.

Franco M; Jeggari A; Peuget S; Böttger F; Selivanova G; Alexeyenko A
Article: SCIENTIFIC REPORTS. 2018;8(1):10064

A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation.

Castell A; Yan Q; Fawkner K; Hydbring P; Zhang F; Verschut V; Franco M; Zakaria SM; Bazzar W; Goodwin J; Zinzalla G; Larsson L-G
Article: NATURE COMMUNICATIONS. 2018;9(1):1107

A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Pastor Fernández A; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Färnegårdh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Håkansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Laín S
Journal article: CANCER RESEARCH. 2016;76(14_Supplement):1227

Abstract 1227: New small molecules targeting MYC:MAX interactions that inhibits tumor cell growth in a MYC-dependent manner

Castell A; Ridderstråle K; Yan Q; Zhang F; Hydbring P; Franco M; Goodwin J; Müller I; Zakaria SM; Johansson L; Larsson L-G
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2013;210(3):563-579

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination.

Anderberg C; Cunha SI; Zhai Z; Cortez E; Pardali E; Johnson JR; Franco M; Páez-Ribes M; Cordiner R; Fuxe J; Johansson BR; Goumans M-J; Casanovas O; ten Dijke P; Arthur HM; Pietras K
Journal article: JOURNAL OF CELL BIOLOGY. 2013;200(4):i10

Deficiency for endoglin in tumor vasculature weakens the endothelial barrier to metastatic dissemination

Anderberg C; Cunha SI; Zhai Z; Cortez E; Pardali E; Johnson JR; Franco M; Páez-Ribes M; Cordiner R; Fuxe J; Johansson BR; Goumans M-J; Casanovas O; Dijke PT; Arthur HM; Pietras K
Article: HORMONE AND METABOLIC RESEARCH. 2011;43(12):884-889

Use of a mouse model of pancreatic neuroendocrine tumors to find pericyte biomarkers of resistance to anti-angiogenic therapy.

Franco M; Pàez-Ribes M; Cortez E; Casanovas O; Pietras K
Article: BLOOD. 2011;118(10):2906-2917

Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression.

Franco M; Roswall P; Cortez E; Hanahan D; Pietras K
Article: SCIENCE. 2006;313(5794):1785-1787

Therapy-induced acute recruitment of circulating endothelial progenitor cells to tumors.

Shaked Y; Ciarrocchi A; Franco M; Lee CR; Man S; Cheung AM; Hicklin DJ; Chaplin D; Foster FS; Benezra R; Kerbel RS
Article: CANCER RESEARCH. 2006;66(7):3639-3648

Targeted anti-vascular endothelial growth factor receptor-2 therapy leads to short-term and long-term impairment of vascular function and increase in tumor hypoxia.

Franco M; Man S; Chen L; Emmenegger U; Shaked Y; Cheung AM; Brown AS; Hicklin DJ; Foster FS; Kerbel RS
Article: CANCER RESEARCH. 2006;66(3):1664-1674

Low-dose metronomic daily cyclophosphamide and weekly tirapazamine: a well-tolerated combination regimen with enhanced efficacy that exploits tumor hypoxia.

Emmenegger U; Morton GC; Francia G; Shaked Y; Franco M; Weinerman A; Man S; Kerbel RS
Article: MOLECULAR CARCINOGENESIS. 2003;37(2):83-90

Modulation of the angiogenesis response through Ha-ras control, placenta growth factor, and angiopoietin expression in mouse skin carcinogenesis.

Larcher F; Franco M; Bolontrade M; Rodriguez-Puebla M; Casanova L; Navarro M; Yancopoulos G; Jorcano JL; Conti CJ
Article: ONCOLOGY RESEARCH. 2002;13(3):147-160

Embryonal mass and hormone-associated effects of pregnancy inducing a differential growth of four murine tumors.

Bustuoabad OD; di Gianni PD; Franco M; Kordon EC; Vanzulli SI; Meiss RP; Grion LC; Díaz GS; Nosetto SH; Hockl P; Lombardi MG; Pasqualini CD; Ruggiero RA
Article: ONCOLOGY REPORTS. 2000;7(5):1053-1063

Two different types of concomitant resistance induced by murine tumors: morphological aspects and intrinsic mechanisms.

Franco M; Bustuoabad OD; Di Gianni PD; Meiss RP; Vanzulli S; Buggiano V; Pasqualini CD; Ruggiero RA
Article: ONCOLOGY REPORTS. 1999;6(5):1073-1084

Inhibition of metastases by a serum factor associated to concomitant resistance induced by unrelated murine tumors.

Di Gianni P; Franco M; Meiss RP; Vanzulli S; Piazzon I; Pasqualini CD; Bustuoabad OD; Ruggiero RA
Article: ONCOLOGY REPORTS. 1997;4(5):1005-1010

A variable neovascularization threshold in tumor-bearing mice.

Bustuoabad O; Digianni P; Ruggiero R; Franco M; Gonzalez M; Pasqualini C
Article: BRITISH JOURNAL OF CANCER. 1996;74(2):178-186

A serum-mediated mechanism for concomitant resistance shared by immunogenic and non-immunogenic murine tumours.

Franco M; Bustuoabad OD; di Gianni PD; Goldman A; Pasqualini CD; Ruggiero RA
Article: MEDICINA-BUENOS AIRES. 1996;56(4):393-396

The role of apoptosis in the inhibition of a secondary tumor by concomitant resistance in a mouse model of metastases.

Franco M; Bekinschtein P; di Gianni P; Bustuoabad OD; Vanzulli S; Ruggiero RA

Alla övriga publikationer

Meeting abstract: CANCER RESEARCH. 2018;78(13):3952

Selective high affinity MYC- binding compound inhibits MYC-MAX interaction and MYC-dependent tumor cell growth

Castell A; Yan Q; Fawkner K; Hydbring P; Zhang F; Verschut V; Franco M; Zinzalla G; Larsson L-G
Corrigendum: NATURE COMMUNICATIONS. 2018;9(1):2071

Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW; van Leeuwen IMM; Drummond CJ; Chu S; Healy AR; Popova G; Pastor Fernández A; Mollick T; Darekar S; Sedimbi SK; Nekulova M; Sachweh MCC; Campbell J; Higgins M; Tuck C; Popa M; Safont MM; Gelebart P; Fandalyuk Z; Thompson AM; Svensson R; Gustavsson A-L; Johansson L; Färnegårdh K; Yngve U; Saleh A; Haraldsson M; D'Hollander ACA; Franco M; Zhao Y; Håkansson M; Walse B; Larsson K; Peat EM; Pelechano V; Lunec J; Vojtesek B; Carmena M; Earnshaw WC; McCarthy AR; Westwood NJ; Arsenian-Henriksson M; Lane DP; Bhatia R; McCormack E; Laín S
Preprint: BIORXIV. 2018

Robust and clinically relevant prediction of response to anti-cancer drugs via network integration of molecular profiles

Franco M; Jeggari A; Peuget S; Böttger F; Selivanova G; Alexeyenko A
Published conference paper: MEDICINA-BUENOS AIRES. 1996;56 Suppl 1:57-64

[Concomitant antitumor resistance].

Ruggiero RA; Di Gianni PD; Franco M; Bustuoabad OD
Published conference paper: MEDICINA-BUENOS AIRES. 1996;56 Suppl 1:25-31

[Role of connective tissue in the tumor-host relationship].

Bustuoabad OD; di Gianni PD; Genovese JA; Falcó R; Franco M; Ruggiero RA
Other: MEDICINA-BUENOS AIRES. 1995;55(1):45-47

A maternally-inherited alteration in the T cell repertoire of BALB/c mice.

Goldman A; Buggiano V; Franco M; Déroche A; Nepomnaschy I; Piazzon I

Anställningar

Forskningssamordnare, Medicin, Huddinge, Karolinska Institutet, 2024-2024
Research Associate, Tumor Angiogenesis, Ludwig Cancer Research, 2006-2008

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