Animal experimental core facilities

At Karolinska Institutet, the managing organisation for all aspects of animal experimentation in research is Comparative Medicine. However, our scientists also have access to animal facilities managed by the Karolinska University Hospital.

Core Facility for Germ-free Research

Germ-free (GF) mice are derived and raised in an environment devoid of resident bacterial flora (microbiota). At Karolinska Institutet, GF models are housed at the Core Facility for Germ-free Research (CFGR). This core facility is a part of the Karolinska Institutet Mouse Models (KIMM), and offers its services to academic researchers as well as to biotech and pharmaceutical industries.

More about the CFGR
 

Import Portal

The KIMM Import Portal (Portalen in Swedish) is the animal quarantine core facility within the Karolinska Institutet Mouse Models (KIMM) organisation.

More about the portal
 

Karolinska Experimental Research and Imaging Centre

Karolinska Experimental Research and Imaging Centre (KERIC) conducts Imaging analyses in experimental systems in combination with experimental surgery in large animals like swine as well as in rodents. This facility is managed by the Karolinska University Hospital in Solna (North Campus area). 

More about KERIC

Karolinska Institutet Mouse Models

The Karolinska Institutet Mouse Models (KIMM) is a core facility umbrella offering production, phenotype analyses, archiving of mouse mutants and experimental platforms to understand the role of genes and the microbiota. The KIMM umbrella facility includes the KCTT facility, the Germ-free facility, the Mouse Clinic, and an import portal.

More about KIMM
 

Morphological Phenotype Analysis

Morphological Phenotype Analysis (FENO) facility specialises  in the pathology of genetically engineered mice. This core facility is managed by the Karolinska University Hospital in Felmingsberg (South Campus area).

More about FENO
 

Mouse Clinic

The mouse clinic of KIMM (KICM) offers researchers the possibility to document the health of their genetically modified mouse strains according to international standards. Researchers may also chose between select analyses or a combination of analyses such as hematological-, physiological- and pathological and/or behavioural analyses. 

More about KICM
 

Preclinical Laboratory Portal

The Preclinical Laboratory (PKL) offers cryopreservation techniques and re-derivation services. Managed by the Karolinska University Hospital in Huddinge (South Campus area).

More about the PKL
 

Transgene Technologies

The Karolinska Center for Transgene Technologies (KCTT) offers generation and storage of genetically modified mice and related techniques. The KCTT facility is a part of Karolinska Institutet Mouse Models (KIMM).

More about the KCTT

Zebrafish Core Facility

https://en.wikipedia.org/wiki/Zebrafish#/media/File:Zebrafisch.jpgThe Zebrafish Core Facility provides researchers with fish from wildtype lines, as well as offer the possibility of bringing in mutant/transgenic fish lines of interest from other laboratories.

More about the Zebrafish facility

Core facility