I am a biologist trained at the University of Uppsala during the 1990s. My research focuses on understanding how our inherited genes influence health, both directly and through behaviour and lifestyle.
- Twin models
- Heritability, variance partitioning
- Large scale gene mapping for complex disease and other traits
- Genetic susceptibility and predisposition
Leading the Swedish Twin Registry
I am in charge of the Swedish Twin Registry (STR) with responsibility for data/sample collection, handling of research applications, data withdrawals and research collaborations. I am also chair of the STR Steering Committee. The epidemiologic and genetic data available in the STR are utilized in studies of a large number of diseases and health related traits by various groups in Sweden and abroad.
- MSc, Natural Sciences, Uppsala University (1995)
- PhD, Medical Genetics, Uppsala University (2000)
- Postdoc, Columbia University, New York (2002)
Genome-wide association study identifies 74 loci associated with educational attainment.
Nature 2016 05;533(7604):539-42
One CNV Discordance in NRXN1 Observed Upon Genome-wide Screening in 38 Pairs of Adult Healthy Monozygotic Twins.
Twin Res Hum Genet 2016 Apr;19(2):97-103
Selective serotonin re-uptake inhibitor use during pregnancy: association with offspring birth size and gestational age.
Int J Epidemiol 2016 Feb;45(1):170-7
Dominant Genetic Variation and Missing Heritability for Human Complex Traits: Insights from Twin versus Genome-wide Common SNP Models.
Am. J. Hum. Genet. 2015 Nov;97(5):708-14
Heritability of Perinatal Depression and Genetic Overlap With Nonperinatal Depression.
Am J Psychiatry 2016 Feb;173(2):158-65
Directional dominance on stature and cognition in diverse human populations.
Nature 2015 Jul;523(7561):459-462
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity.
Nat. Neurosci. 2015 Jul;18(7):953-5
Cohort Profile: Swedish Twin Study on Prediction and Prevention of Asthma (STOPPA).
Twin Res Hum Genet 2015 Jun;18(3):273-80
Comparison of heritability of Cystatin C- and creatinine-based estimates of kidney function and their relation to heritability of cardiovascular disease.
J Am Heart Assoc 2015 Jan;4(1):e001467
Large-scale metabolomic profiling identifies novel biomarkers for incident coronary heart disease.
PLoS Genet. 2014 Dec;10(12):e1004801
Current supervision of PhD students
- German Dario Carrasquilla Lopez
Complete publication list
I teach genetics and genetic epidemiology in the Medical and Psychology programs at KI and occasionally at Stockholm University and Uppsala university. I was responsible for the KI graduate course "Genetic Epidemiology" between 2009 and 2015.
Academic honours, awards and prizes
Swedish cancer-thesis of the year award, given by the Swedish Cancer Fund, 2001.
The Hwasserska award for the best medical thesis of the year from Uppsala University, given by the Uppsala Läkaresällskap, 2000.