Postdoc Fellowships 2023 - Project 3

Short title: DNA damage as a driver of adipocyte senescence


Principal Investigator

Research Project

Investigating DNA damage as a driver of adipocyte senescence and inflammation in obese, hyperinsulinemic individuals

Senescent cells, which can release factors that cause inflammation and dysfunction, increase in adipose tissue and associate with obesity and hyperinsulinemia. The proposed project will determine whether oxidative stress and DNA damage in human adipocytes drives adipocyte senescence, and the associated pro-inflammatory secretory profile. A small molecule approach to attenuate adipocyte DNA damage and reverse adipocyte senescence will be investigated.

Project description

Read the complete project description.

Lab webpage

How to apply

The recruitment process has finished.

Content reviewer:
Stefan Nobel