Cardiovascular simulation as clinical decision support in cardiac surgery, cardiology and intensive care – Michael Broomé's research group

The manifold drug, surgical and device treatments in cardiovascular disease and improved diagnostics imposes a need for patient-specific outcome prediction.

Modeling has the potential to bridge the gap between evidence-based medicine proving treatment effects in groups of patients and patient-specific aspects of the disease state necessitating individualization. The current computerized cardiovascular model runs in real-time and allows testing of treatments within minutes and is therefore a realistic clinical tool, although further validation is needed.


Analysis and optimization of cardiac loading in complex cardiovascular disease and mechanical circulatory support – clinical studies enforced by computerized cardiovascular physiology simulation.


  • Professor Dirk Donker MD PhD, Cardiovascular and Respiratory Physiology (CRPH), Science and Technology, University of Twente, The Netherlands.
    Consultant intensivist/cardiologist Utrecht Medical Center, The Netherlands
  • Associate Professor Clinical Physiology Marcus Carlsson, Lunds University Hospital, Sweden. Clinical Investigator, National Institute of Health (NIH), Bethesda, Maryland, USA.
  • Associate Professor Pediatric Cardiology Petru Liuba, Lunds University Hospital, Sweden
  • Associate Professor Pediatric Cardiology Nina Hakacova, Lunds University Hospital, Sweden


Selected publications


Michael Broomé: PhD 2001 Umeå Universitet, Anestesiologi och Intensivvård
“Exogenous Angiotensin II – an experimental study of integrated circulatory effects in heart, splanchnic organs and kidney”
Handledare: Professor Björn Biber

Elira Maksuti: 2016 KI and KTH.
"Biomedical Engineering. Computer simulation of hemodynamics and ultrasound-based elastography for better diagnosis and treatment of cardiovascular diseases"

Magnus Larsson: 2015 KI.
"Pediatric Surgery. ECMO and Trauma"


  • Swedish Heart Lung Foundation 2019
  • Stockholm City Council ALF/SLL 2017-2018
  • Swedish Research Council 2013-2015