Developing Brains 2023
How can a single cell give rise to complex structures such as the central (brain/spinal cord) and enteric (brain in the gut) nervous systems? This is the overarching question in neural development; understanding how such intricate structures are assembled gives not only crucial knowledge about these nervous systems, but also important insight to the etiology of some of our most common diseases.
The 10th edition of the KI Conference “Developing Brains” gathers some of the leading scientists working on critical questions ranging from transcriptional and functional heterogeneity of neural cell types, mechanisms regulating their development and creation of mature neural circuits, and how it can affect disorders of the central nervous system.
The 10th edition of the KI Conference “Developing Brains” gathers some of the leading scientists working on critical questions ranging from transcriptional and functional heterogeneity of neural cell types, mechanisms regulating their development and creation of mature neural circuits, and how it can affect disorders of the central nervous system.
Registration
The registration is now closed since the conference is oversubscribed.
Please note that the conference is in person and that it will not be broadcasted.
Final program
October 18th
Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet
Chair: Jens Hjerling-Leffler
14.00 - 14.10 Welcome
Jens Hjerling-Leffler
14.10 – 15.00 Scalable investigation of gene function and their organ-wide action
Xin Jin, Scripps
15.00 – 15.50 The Developmental Origins of Neuropsychiatric Disorders
Daniel Geschwind, UCLA
15.50 – 16.20 COFFEE BREAK
16.20 – 17.10 Systematic investigation of allelic regulatory activity of psychiatric disorder risk variants
Hyejung Won, Univ. North Carolina
17.10 – 18.00 Genetic, cellular, and intercellular strategies of human brain development
Tomasz Nowakowski, UCSF
October 19th
Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet
Chair: Gonçalo Castelo-Branco
09.30 - 10.20 Microglia in early brain wiring: from circuit assembly to structural integrity
Sonia Garel, College de France/École Normale Supérieure
10.20 - 11.10 Activity dependent myelin changes in the adult CNS
Thora Karadottir, Cambridge University
11.10 – 12.00 Neuron-glia interactions in health and disease
Ethan Hughes, Univ. of Colorado
12.00-13.00 Lunch
Chair: Francois Lallemend
13.00 – 13.50 Clonal analysis helps to understand fate selection mechanisms during development
Igor Adameyko, Medical University of Vienna
13.50 – 14.40 Enteric neuron subtype identities emerge through a stepwise diversification principle
Ulrika Marklund, Karolinska Institutet
14.40 – 15.20 COFFEE BREAK
Chair: Ulrika Marklund
15.20 – 16.10 Schwann cell precursor-derived neurogenesis: its distribution, mechanism and pathological implications
Hideki Enomoto, Kobe University
16.10 – 17.00 Mapping the “second brain”: development, organization and function of the enteric nervous system
Julia Kaltschmidt, Stanford University
17.00 – 17.50 Interneurons succumb to pyramidal peer pressure
Gord Fishell, Harvard Medical School
October 20th
Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet
Chair: François Lallemend
09.00 – 09.50 Spatial enhancer activation determines inhibitory neuron identity
Christian Mayer, MPI Neurobiology
09.50 - 10.40 Temporal control of neurogenesis
Bassem Hassan, Paris Brain Institute
10.40 – 11.00 COFFEE BREAK
Chair: Goncalo Castelo-Branco and Ulrika Marklund
11.00 – 11.50 The choroid plexus: a key player in brain development and an unexplored brain barrier
Laura Pellegrini, Kings College London
11.50 – 12.40 From Stem Cells to Organoids to Assembloids and Toward Buildings Human Circuits in Living Systems to Study Development and Disease
Sergiu Pasca, Stanford University
12.40 – 12.50 Concluding remarks
Gonçalo Castelo-Branco
12.50 – 14.00 Departure Lunch