Developing Brains 2023

How can a single cell give rise to complex structures such as the central (brain/spinal cord) and enteric (brain in the gut) nervous systems? This is the overarching question in neural development; understanding how such intricate structures are assembled gives not only crucial knowledge about these nervous systems, but also important insight to the etiology of some of our most common diseases.

The 10th edition of the KI Conference “Developing Brains” gathers some of the leading scientists working on critical questions ranging from transcriptional and functional heterogeneity of neural cell types, mechanisms regulating their development and creation of mature neural circuits, and how it can affect disorders of the central nervous system.

The 10th edition of the KI Conference “Developing Brains” gathers some of the leading scientists working on critical questions ranging from transcriptional and functional heterogeneity of neural cell types, mechanisms regulating their development and creation of mature neural circuits, and how it can affect disorders of the central nervous system.

Registration

The registration is now closed since the conference is oversubscribed.

Please note that the conference is in person and that it will not be broadcasted.

Final program

October 18th 

Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet

Chair: Jens Hjerling-Leffler

14.00 - 14.10 Welcome 
Jens Hjerling-Leffler

14.10 – 15.00  Scalable investigation of gene function and their organ-wide action
Xin Jin, Scripps

15.00 – 15.50 The Developmental Origins of Neuropsychiatric Disorders
Daniel Geschwind, UCLA
 

15.50 – 16.20 COFFEE BREAK

16.20 – 17.10 Systematic investigation of allelic regulatory activity of  psychiatric disorder risk variants
Hyejung Won, Univ. North Carolina

17.10 – 18.00  Genetic, cellular, and intercellular strategies of human brain development
Tomasz Nowakowski, UCSF

October 19th 

Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet

Chair: Gonçalo Castelo-Branco

09.30 - 10.20 Microglia in early brain wiring: from circuit assembly to structural integrity
Sonia Garel, College de France/École Normale Supérieure

10.20 - 11.10 Activity dependent myelin changes in the adult CNS
Thora Karadottir, Cambridge University

11.10 – 12.00  Neuron-glia interactions in health and disease               
Ethan Hughes, Univ. of Colorado

12.00-13.00 Lunch

Chair: Francois Lallemend

13.00 – 13.50  Clonal analysis helps to understand fate selection mechanisms during development
Igor Adameyko, Medical University of Vienna

13.50 – 14.40 Enteric neuron subtype identities emerge through a stepwise diversification principle
Ulrika Marklund, Karolinska Institutet

14.40 – 15.20 COFFEE BREAK

Chair: Ulrika Marklund

15.20 – 16.10 Schwann cell precursor-derived neurogenesis: its distribution, mechanism and pathological implications
Hideki Enomoto, Kobe University 

16.10 – 17.00 Mapping the “second brain”: development, organization and function of the enteric nervous system
Julia Kaltschmidt, Stanford University

17.00 – 17.50 Interneurons succumb to pyramidal peer pressure
Gord Fishell, Harvard Medical School

October 20th 

Eva & Georg Klein lecture hall, Biomedicum, Karolinska Institutet

Chair: François Lallemend

09.00 – 09.50 Spatial enhancer activation determines inhibitory neuron identity
Christian Mayer, MPI Neurobiology

09.50 - 10.40 Temporal control of neurogenesis
Bassem Hassan, Paris Brain Institute

10.40 – 11.00 COFFEE BREAK

Chair: Goncalo Castelo-Branco and Ulrika Marklund

11.00 – 11.50  The choroid plexus: a key player in brain development and an unexplored brain barrier                  
Laura Pellegrini, Kings College London

11.50 – 12.40 From Stem Cells to Organoids to Assembloids and Toward Buildings Human Circuits in Living Systems to Study Development and Disease
Sergiu Pasca, Stanford University

12.40 – 12.50 Concluding remarks
Gonçalo Castelo-Branco

12.50 – 14.00 Departure Lunch

GC
Content reviewer:
Sara Lidman
01-07-2024