News from the Centre for Translational Microbiome Research (CTMR)
CTMR and Covid-19
All news regarding CTMR and Covid-19 can be reached here.
Dagens Nyheter: "Tecken på bukspottkörtelcancer finns i tarmfloran", March 21, 2022.
Test av avföringsprov kan vara en enkel och billig screeningmetod för att tidigt hitta bukspottkörtelcancer. En viss sammansättning av bakterier i tarmfloran kan användas som ett tecken, en biomarkör, för att upptäcka personer med en ökad cancerrisk.
Juan Du, Recipient of Ingvar Carlsson Award 2017-2021 from Stiftelsen för Strategisk Forskning (SSF)
Video: "They use the body’s good bacteria against diseases", YouTube, October 1 2021
Juan Du and the researchers at KI are investigating how the body’s naturally occurring good bacteria, the so-called commensal bacteria, can protect us against infections, such as HPV, human papillomavirus. The bacteria could be used for preventive purposes, in so-called probiotics, which can strengthen the body’s defenses and reduce the need for antibiotics.
Oncobiome website launched - September 7th 2020
The new Oncobiome website can be reached here, with information and newsletters.
"Why the recent Rebiotix trial result is a bigger deal many seem to think…" - May 14th 2020
"Last week, Ferring-owned microbiome firm Rebiotix reported positive preliminary findings from its phase 3 trial for RBX2660 – an investigational, non-antibiotic, microbiome-based therapy developed to reduce Clostridioides difficile (C. diff) infection recurrences."
Read more here.
First project to create atlas of human microbiome, December 2019
The five-year Million Microbiome of Humans Project (MMHP) is now underway, as KI researchers begin leading the efforts to construct a genome atlas of the human microbiome.
More information about the project can be found here and information from MGI here.
Lars Engstrand featured on Swedish National TV4 November 2019 discussing treatment for bacterial vaginosis (in Swedish)
CTMR forms collaboration with the BGI Group
MGI Tech Co., Ltd. (MGI), a subsidiary of BGI Group, have announced a collaboration in microbiome research with the Centre for Translational Microbiome Research (CTMR) at Karolinska Institutet.
The project is lead by Professor Lars Engstrand and Professor Mathias Uhlén, supported by Karolinska Institutet and Ferring Pharmaceuticals, using MGI’s DNBSEQTM technology to generate high quality shotgun metagenomics data from one of the largest microbiome biobanks. The collaboration will form a foundation for understanding the contribution of the microbiome to normal physiology and pathophysiology, and opens opportunities for development of novel therapies to address gastroenterology, cancer, reproductive health and neonatology.
The long-term objective of CTMR is to identify and characterize factors (both microbial and host related) that determine or modify the excess risk of disease outcome e.g. to determine the relationship between human health and changes in our gut microbiome.
CTMR receives European funding through the Horizon 2020 framework and the ONCOBIOME project
CTMR, under the lead of Professor Lars Engstrand, has received European funding through the Horizon 2020 framework and is one of the 17 collaborators of the ONCOBIOME project (2019-2023). This ONCOBIOME project aims to explore the role of the microbiome in cancer, from early detection and diagnosis to treatment and prognosis.“
Eva Doorakkers successful PhD defence on Friday January 25th
Eva Doorakkers from the group Upper GI Surgery defended her thesis "Helicobacter pylori eradication treatment and the risk of gastric and oesophageal cancer" on January 25th, 2019. Main Supervisor is Nele Brusselaers.
Supervisors: Assoc. Prof Nele Brusselaers, Prof Lars Engstrand, Prof Jesper Lagergren
Opponent: Prof Ernst Kuipers
KI, Ferring and Rebiotix extend collaboration to research next generation of microbiome treatments
KI and Ferring Pharmaceuticals announced today a five-year extension of their collaboration to explore the potential of the human microbiome in reproductive medicine and women’s health and gastroenterology.
CTMR collaboration with EURAC on studies of the Ötzi gut microbiome
Dr Frank Maixner, EURAC institute for studies of mummies and the iceman, Bolzano, Italy, visited The Centre for Translational Microbiome Research (CTMR) and gave a lecture on "The 5300-year-old Helicobacter pylori genome of the Iceman - the story and the research" this December.
Lars Engstrand and Ina Schuppe Koistinen featured on Swedish National TV4 February 2018
Lars Engstrand has been featured in the TV4 program Malou efter tio. The program focuses on the connction between long term usage of coagulants and stomach cancer
Unlocking the Secrets of the Microbiome
A new film summarizing the work and personalities at the Centre for Translational Microbiome Research (CTMR)
Ferring Pharmaceuticals site visit at CTMR/MTC and open house for The Center for Translational Microbiome Research (CTMR) June 13 2016
The Center for Translational Microbiome Research, CTMR, hosted the microbiome project team from Ferring Pharmaceuticals May 17th. The team visited the new premises at MTC and SciLifeLab and discussed projects within the ongoing collaboration.
MTC:ers are all welcome to CTMR Open House, June 13 from 2 - 16.30 pm.
Please, join us during this afternoon and get the opportunity to see our new premises, learn about our research and meet with personnel, students and postdocs at the Center.