Research group Enikö Sonkoly

Publications

All publications from group members

• Doctoral thesis: 2025

  Non-coding RNAs in psoriasis : insights into epidermal dysregulation and inflammation

  Freisenhausen JC
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2025;145(7):1552-1554

  The miRacle of Epidermal Homeostasis.

  Sonkoly E
• Article: EXPERIMENTAL DERMATOLOGY. 2025;34(2):e70054

  RNA Sequencing Reveals the Long Non-Coding RNA Signature in Psoriasis Keratinocytes and Identifies CYDAER as a Long Non-Coding RNA Regulating Epidermal Differentiation

  Freisenhausen JC; Luo L; Kelemen E; Elton J; Skoog V; Pivarcsi A; Sonkoly E
• Journal article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2024;144(11):2349-2350

  Young ESDR: Engaging and Nurturing the Next-Generation Skin Research Community.

  Ganier C; Callewaert C; Matos TR; Sonkoly E; Dyring-Andersen B; Rajan N
• Article: BRITISH JOURNAL OF DERMATOLOGY. 2024;191(4):635-637

  Single-cell transcriptomic analysis identifies infiltrating plasmacytoid dendritic cells in psoriasis epidermis

  Luo L; Cheng H; Liu Z; Olszewski P; Pasquali L; Xu N; Enge M; Pivarcsi A; Sonkoly E
• Article: ACTA DERMATO-VENEREOLOGICA. 2024;104:adv18672

  Guselkumab in Patients with Scalp Psoriasis: A post hoc Analysis of the VOYAGE 2 Phase III Randomized Clinical Trial

  Sonkoly E; Maul J-T; Megna M; Gorecki P; Crombag E; Buyze J; Savage L
• Article: BRITISH JOURNAL OF DERMATOLOGY. 2024;190(3):415-426

  Long noncoding RNA plasmacytoma variant translocation 1 is overexpressed in cutaneous squamous cell carcinoma and exon 2 is critical for its oncogenicity

  Li C; Sun C; Mahapatra KD; Riihilae P; Knuutila J; Nissinen L; Lapins J; Kaehaeri V-M; Homey B; Sonkoly E; Pivarcsi A
• Corrigendum: BRITISH JOURNAL OF DERMATOLOGY. 2024;191(1):E1

  Long noncoding RNA plasmacytoma variant translocation 1 is overexpressed in cutaneous squamous cell carcinoma and exon 2 is critical for its oncogenicity (vol 190, pg 415, 2024)

  Li C; Sun C; Das Mahapatra K; Riihila P; Knuutila J; Nissinen L; Lapins J; Kahari V-M; Homey B; Sonkoly E; Pivarcsi A
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(12):2386-2396

  MicroRNA-23b Plays a Tumor-Suppressive Role in Cutaneous Squamous Cell Carcinoma and Targets Ras-Related Protein RRAS2

  Sun C; Das Mahapatra K; Elton J; Li C; Fernando W; Lohcharoenkal W; Lapins J; Homey B; Sonkoly E; Pivarcsi A
• Review: ACTA DERMATO-VENEREOLOGICA. 2023;103:adv13356

  Molecular Organization of the Skin Barrier

  Norlen L
• Doctoral thesis: 2023

  Deciphering the complexity of psoriasis : non-coding RNAs and cellular interactions

  Luo L
• Article: ARTHRITIS RESEARCH & THERAPY. 2023;25(1):169

  Nail psoriasis dynamics during biologic treatment and withdrawal in patients with psoriasis who may be at high risk of developing psoriatic arthritis: a post hoc analysis of the VOYAGE 2 randomized trial

  Tillett W; Egeberg A; Sonkoly E; Gorecki P; Tjaernlund A; Buyze J; Wegner S; Mcgonagle D
• Review: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(9):1667-1677

  A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization

  Almet AA; Yuan H; Annusver K; Ramos R; Liu Y; Wiedemann J; Sorkin DH; Landen NX; Sonkoly E; Haniffa M; Nie Q; Lichtenberger BM; Luecken MD; Andersen B; Tsoi LC; Watt FM; Gudjonsson JE; Plikus MV; Kasper M
• Article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2023;63(15):4900-4911

  Understanding Drug Skin Permeation Enhancers Using Molecular Dynamics Simulations

  Wennberg C; Lundborg M; Lindahl E; Norlen L
• Article: CELL DEATH DISCOVERY. 2023;9(1):260

  Cutaneous squamous cell carcinoma-derived extracellular vesicles exert an oncogenic role by activating cancer-associated fibroblasts

  Li C; Sun C; Lohcharoenkal W; Ali MM; Xing P; Zheng W; Gorgens A; Gustafsson MO; EL Andaloussi S; Sonkoly E; Pivarcsi A
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023;143(6):999-1010

  The Long Noncoding RNA LINC00958 Is Induced in Psoriasis Epidermis and Modulates Epidermal Proliferation

  Luo L; Pasquali L; Srivastava A; Freisenhausen JC; Pivarcsi A; Sonkoly E
• Corrigendum: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2023;152(1):307

  Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis- and psoriasis-associated genes (vol 147, pg 1742, 2021)

  Sahlen P; Spalinskas R; Asad S; Mahapatra KD; Hojer P; Anil A; Eisfeldt J; Srivastava A; Nikamo P; Mukherjee A; Kim K-H; Bergman O; Stahle M; Sonkoly E; Pivarcsi A; Wahlgren C-F; Nordenskjold M; Taylan F; Tapia-Paez I; Bradley M
• Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2022;36(11):2076-2086

  Children with psoriasis and COVID-19: factors associated with an unfavourable COVID-19 course, and the impact of infection on disease progression (Chi-PsoCov registry)

  Zitouni J; Bursztejn A-C; Fortina AB; Beauchet A; Di Lernia V; Lesiak A; Thomas J; Topkarci Z; Murashkin N; Brzezinski P; Torres T; Chiriac A; Luca C; McPherson T; Akinde M; Maruani A; Epishev R; de la Cruz HV; Luna PC; de la Breteque MA; Lasek A; Bourrat E; Bachelerie M; Mallet S; Steff M; Bellissen A; Neri I; Zafiriou E; van den Reek JMPA; Sonkoly E; Mahil SK; Smith CH; Flohr C; Bachelez H; Mahe E
• Article: BIOPHYSICAL JOURNAL. 2022;121(20):3837-3849

  Skin permeability prediction with MD simulation sampling spatial and alchemical reaction coordinates

  Lundborg M; Wennberg C; Lidmar J; Hess B; Lindahl E; Norlen L
• Article: BRITISH JOURNAL OF DERMATOLOGY. 2022;187(2):211-222

  miR-378a regulates keratinocyte responsiveness to interleukin-17A in psoriasis

  Xia P; Pasquali L; Gao C; Srivastava A; Khera N; Freisenhausen JC; Luo L; Rosen E; Lierop A; Homey B; Pivarcsi A; Sonkoly E
• Review: JAMA DERMATOLOGY. 2022;158(5):561-572

  International eDelphi Study to Reach Consensus on the Methotrexate Dosing Regimen in Patients With Psoriasis.

  van Huizen AM; Menting SP; Gyulai R; Iversen L; van der Kraaij GE; Middelkamp-Hup MA; Warren RB; Spuls PI; SPIN MTX Consensus Survey Study Group; Schejtman AA; Egeberg A; Firooz A; Kumar AS; Oakley A; Foulkes A; Ramos AMC; Fougerousse A-C; Carija A; Akman-Karakas A; Horváth B; Fábos B; Matlock BH; Claréus BW; Castro C; Ferrándiz C; Correa CC; Marchesi C; Goujon C; Gonzalez C; Maldonado-García C; Hong C-H; Griffiths CEM; Vestergaard C; Echeverría CM; de la Cruz C; Conrad C; Törocsik D; Drvar DL; Balak D; Jullien D; Appelen D; Kim DH; de Jong EMGJ; El Gamal E; Laffitte E; Mahé E; Sonkoly E; Colombo EP; Vilarrasa E; Willaert F; Novoa FD; Handjani F; Valenzuela F; Vílchez-Márquez F; Gonzalez GO; Krisztián G; Damiani G; Krnjevic-Pezic G; Pellerano G; Carretero G; Hunter HJA; Riad H; Oon HH; Boonen HPJ; Moussa IO; García-Doval I; Csányi I; Brajac I; Turchin I; Grozdev I; Weinberg JM; Nicolopoulos J; Wells J; Lambert JLW; Ingram JR; Prinz JC; de Souza Sittart JA; Sanchez JL; Hsiao JP-F; Castro-Ayarza JR; Maul J-T; van den Reek JMPA; Trcko K; Barber K; Reich K; Gebauer KA; Khobzei K; Maul LV; Massari LP; Fardet L; le Cleach L; Misery L; Chandrashekar L; Muresanu LI; Lecluse L; Skov L; Frez ML; Babic LT; Puig L; Gomez LC; Ramam M; Dutil M; El-Sayed MH; Olszewska M; Schram ME; Franco MD; Llamas-Velasco M; Gonçalo M; Velásquez-Lopera MM; Abad ME; de Oliveira MDFSP; Seyger MMB; Kaštelan M; Rademaker M; Sikora M; Lebwohl M; Wiseman MC; Ferran M; van Doorn M; Danespazhooh M; Bylaite-Bucinskiene M; Gooderham MJ; Polic MV; de Rie MA; Zheng M; Gómez-Flores M; Salleras I Redonnet M; Silverberg NB; Doss N; Yawalkar N; Chosidow O; Zargari O; de la Cueva P; Fernandez-Peñas P; Cárdenas Rojas PJ; Gisondi P; Grewal P; Sator P; Luna PC; Félix PAO; Varela P; Holló P; Cetkovska P; Calzavara-Pinton P; Ghislain P-D; Araujo RR; Romiti R; Kui R; Ceovic R; Vender R; Lafuente-Urrez RF; Del-Río R; Gulin SJ; Handa S; Mahil SK; Kolalapudi SA; Marrón SE; Azimi SZ; Janmohamed SR; da Cruz Costa SA; Choon SE; Urbancek S; Ayanlowo O; Margasin SM; Wong T-W; Mälkönen T; Hurtová T; Reciné TR; Huldt-Nystrøm T; Torres T; Liu T-Y; Leonidze T; Sharma VK; Weightman W; Gulliver W; Veldkamp W
• Editorial comment: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2022;149(4):1213-1215

  Reversal of the disease signature in prurigo nodularis by blocking the itch cytokine

  Sonkoly E
• Review: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(2):285-292

  The Skin's Barrier: A Cryo-EM Based Overview of its Architecture and Stepwise Formation

  Norlen L; Lundborg M; Wennberg C; Narangifard A; Daneholt B
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2022;142(2):333-342.e6

  IL-22 Downregulates Peptidylarginine Deiminase-1 in Human Keratinocytes: Adding Another Piece to the IL-22 Puzzle in Epidermal Barrier Formation

  Padhi A; Srivastava A; Ramesh A; Ehrstrom M; Simon M; Sonkoly E; Eidsmo L; Bergman P; Lysell J
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(51):e2100687118

  A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.

  Landegren N; Ishii N; Aranda-Guillén M; Gunnarsson HI; Sardh F; Hallgren Å; Ståhle M; Hagforsen E; Bradley M; Edqvist P-HD; Pontén F; Mäkitie O; Eidsmo L; Norlén L; Achour A; Dahlbom I; Korponay-Szabó I; Agardh D; Alimohammadi M; Eriksson D; Hashimoto T; Kämpe O
• Article: NATURE COMMUNICATIONS. 2021;12(1):6943

  Stroke subtype-dependent synapse elimination by reactive gliosis in mice

  Shi X; Luo L; Wang J; Shen H; Li Y; Mamtilahun M; Liu C; Shi R; Lee J-H; Tian H; Zhang Z; Wang Y; Chung W-S; Tang Y; Yang G-Y
• Article: FOOD & FUNCTION. 2021;12(15):6755-6765

  Inhibition of the Ras/ERK1/2 pathway contributes to the protective effect of ginsenoside Re against intimal hyperplasia

  Gao C; Zhang K; Liang F; Ma W; Jiang X; Wang H; Zhan H; Sonkoly E; Hu H; Zhao Z
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(8):1922-1931

  MiR-130a Acts as a Tumor Suppressor MicroRNA in Cutaneous Squamous Cell Carcinoma and Regulates the Activity of the BMP/SMAD Pathway by Suppressing ACVR1

  Lohcharoenkal W; Li C; Das Mahapatra K; Lapins J; Homey B; Sonkoly E; Pivarcsi A
• Review: JOURNAL OF INTERNAL MEDICINE. 2021;290(2):257-278

  Inflammatory bowel disease and psoriasis: modernizing the multidisciplinary approach

  Hedin CRH; Sonkoly E; Eberhardson M; Stahle M
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(6):2225-2235

  Cross-talk between IFN-γ and TWEAK through miR-149 amplifies skin inflammation in psoriasis

  Srivastava A; Luo L; Lohcharoenkal W; Meisgen F; Pasquali L; Pivarcsi A; Sonkoly E
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(5):1243-1253.e6

  Molecular Reorganization during the Formation of the Human Skin Barrier Studied In Situ

  Narangifard A; Wennberg CL; den Hollander L; Iwai I; Han H; Lundborg M; Masich S; Lindahl E; Daneholt B; Norlen L
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2021;147(5):1742-1752

  Chromatin interactions in differentiating keratinocytes reveal novel atopic dermatitis- and psoriasis-associated genes

  Sahlen P; Spalinskas R; Asad S; Das Mahapatra K; Hojer P; Anil A; Eisfeldt J; Srivastava A; Nikamo P; Mukherjee A; Kim K-H; Bergman O; Stahle M; Sonkoly E; Pivarcsi A; Wahlgren C-F; Nordenskjold M; Taylan F; Bradley M; Tapia-Paez I
• Article: JAMA DERMATOLOGY. 2021;157(6):1-8

  Long-term Outcomes and Prognosis in New-Onset Psoriasis

  Svedbom A; Mallbris L; Larsson P; Nikamo P; Wolk K; Kjellman P; Sonkoly E; Eidsmo L; Lindqvist U; Stahle M
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2021;141(3):659-671

  miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes

  Li D; Peng H; Qu L; Sommar P; Wang A; Chu T; Li X; Bi X; Liu Q; Serezal IG; Rollman O; Lohcharoenkal W; Zheng X; Angelstig SE; Grunler J; Pivarcsi A; Sonkoly E; Catrina S-B; Xiao C; Stahle M; Mi Q-S; Zhou L; Landen NX
• Editorial comment: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2020;140(9):S185-S186

  Looking Back to the Future: ESDR Academy for Future Leaders in Dermatology, 2011

  Sonkoly E
• Article: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2020;34(6):1248-1256

  Circulating microRNAs in extracellular vesicles as potential biomarkers for psoriatic arthritis in patients with psoriasis

  Pasquali L; Svedbom A; Srivastava A; Rosen E; Lindqvist U; Stahle M; Pivarcsi A; Sonkoly E
• Article: SCIENTIFIC REPORTS. 2020;10(1):3637

  A comprehensive analysis of coding and non-coding transcriptomic changes in cutaneous squamous cell carcinoma

  Das Mahapatra K; Pasquali L; Sondergaard JN; Lapins J; Nemeth IB; Baltas E; Kemeny L; Homey B; Moldovan L-I; Kjems J; Kutter C; Sonkoly E; Kristensen LS; Pivarcsi A
• Article: TRANSLATIONAL STROKE RESEARCH. 2019;10(6):695-704

  Dynamic Detection of Thrombolysis in Embolic Stroke Rats by Synchrotron Radiation Angiography.

  Wang L; Zhou P; Mu Z; Lin X; Jiang L; Cheng Z; Luo L; Xu Z; Geng J; Wang Y; Zhang Z; Yang G-Y
• Letter: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2019;139(12):2547-2550.e12

  Next-Generation Sequencing Identifies the Keratinocyte-Specific miRNA Signature of Psoriasis

  Srivastava A; Meisgen F; Pasquali L; Munkhammar S; Xia P; Stahle M; Landen NX; Pivarcsi A; Sonkoly E
• Article: CNS NEUROSCIENCE & THERAPEUTICS. 2019;25(9):1030-1041

  L-glutamine protects mouse brain from ischemic injury via up-regulating heat shock protein 70.

  Luo L-L; Li Y-F; Shan H-M; Wang L-P; Yuan F; Ma Y-Y; Li W-L; He T-T; Wang Y-Y; Qu M-J; Liang H-B; Zhang Z-J; Yang G-Y; Tang Y-H; Wang Y-T
• Article: ACTA DERMATO-VENEREOLOGICA. 2019;99(2):196-205

  The Keratinocyte Transcriptome in Psoriasis: Pathways Related to Immune Responses, Cell Cycle and Keratinization

  Pasquali L; Srivastava A; Meisgen F; Das Mahapatra K; Xia P; Landen NX; Pivarcsi A; Sonkoly E
• Article: ACTA DERMATO-VENEREOLOGICA. 2018;98(8):772-775

  Tofacitinib Represses the Janus Kinase-Signal Transducer and Activators of Transcription Signalling Pathway in Keratinocytes

  Srivastava A; Stahle M; Pivarcsi A; Sonkoly E
• Article: SCIENTIFIC REPORTS. 2018;8(1):12990

  Identification of chronological and photoageing-associated microRNAs in human skin

  Srivastava A; Karlsson M; Marionnet C; Bernerd F; Gueniche A; Rawadi CEL; Stahle M; Sonkoly E; Breton L; Pivarcsi A
• Article: JOURNAL OF CONTROLLED RELEASE. 2018;283:269-279

  Predicting drug permeability through skin using molecular dynamics simulation

  Lundborg M; Wennberg CL; Narangifard A; Lindahl E; Norlen L
• Article: JOURNAL OF STRUCTURAL BIOLOGY. 2018;203(2):149-161

  Human skin barrier structure and function analyzed by cryo-EM and molecular dynamics simulation

  Lundborg M; Narangifard A; Wennberg CL; Lindahl E; Daneholt B; Norlen L
• Article: EXPERIMENTAL CELL RESEARCH. 2018;367(2):222-231

  cxcl12 gene engineered endothelial progenitor cells further improve the functions of oligodendrocyte precursor cells.

  Yuan F; Chang S; Luo L; Li Y; Wang L; Song Y; Qu M; Zhang Z; Yang G-Y; Wang Y
• Article: EXPERIMENTAL CELL RESEARCH. 2018;366(2):139-151

  Human skin barrier formation takes place via a cubic to lamellar lipid phase transition as analyzed by cryo-electron microscopy and EM-simulation

  Narangifard A; den Hollander L; Wennberg CL; Lundborg M; Lindahl E; Iwai I; Han H; Masich S; Daneholt B; Norlen L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2018;138(4):882-892

  Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis

  Lohcharoenkal W; Das Mahapatra K; Pasquali L; Crudden C; Kular L; Ulum YZA; Zhang L; Landen NX; Girnita L; Jagodic M; Stahle M; Sonkoly E; Pivarcsi A
• Article: BIOPHYSICAL JOURNAL. 2018;114(5):1116-1127

  Structural Transitions in Ceramide Cubic Phases during Formation of the Human Skin Barrier

  Wennberg CL; Narangifard A; Lundborg M; Norlen L; Lindahl E
• Article: PLOS ONE. 2018;13(11):e0206942

  Extracellular microvesicle microRNAs as predictive biomarkers for targeted therapy in metastastic cutaneous malignant melanoma

  Svedman FC; Lohcharoenkal W; Bottai M; Brage SE; Sonkoly E; Hansson J; Pivarcsi A; Eriksson H
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2017;137(12):2630-2638

  MicroRNA-132 with Therapeutic Potential in Chronic Wounds

  Li X; Li D; Wang A; Chu T; Lohcharoenkal W; Zheng X; Grunler J; Narayanan S; Eliasson S; Herter EK; Wang Y; Ma Y; Ehrstrom M; Eidsmo L; Kasper M; Pivarcsi A; Sonkoly E; Catrina S-B; Stahle M; Landen NX
• Article: SCIENTIFIC REPORTS. 2017;7(1):7797

  MicroRNA-132 promotes fibroblast migration via regulating RAS p21 protein activator 1 in skin wound healing

  Li X; Li D; Wikstrom JD; Pivarcsi A; Sonkoly E; Stahle M; Landen NX
• Article: EXPERIMENTAL DERMATOLOGY. 2017;26(4):375-376

  The expanding microRNA world in psoriasis

  Sonkoly E
• Article: BRITISH JOURNAL OF DERMATOLOGY. 2017;176(4):1021-1027

  Acute skin and hair symptoms followed by severe, delayed eye complications in subjects using the synthetic opioid MT-45

  Helander A; Bradley M; Hasselblad A; Norlen L; Vassilaki I; Backberg M; Lapins J
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2017;139(2):550-561

  MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis

  Srivastava A; Nikamo P; Lohcharoenkal W; Li D; Meisgen F; Landen NX; Stahle M; Pivarcsi A; Sonkoly E
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2016;136(12):2485-2494

  MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC

  Lohcharoenkal W; Harada M; Loven J; Meisgen F; Landen NX; Zhang L; Lapins J; Das Mahapatra K; Shi H; Nissinen L; Kahari V-M; Stahle M; Sonkoly E; Grander D; Arsenian-Henriksson M; Pivarcsi A
• Editorial comment: ACTA DERMATO-VENEREOLOGICA. 2016;96(3):291

  Is Oil a Balsam for Baby Skin?

  Norlen L
• Article: ACTA DERMATO-VENEREOLOGICA. 2016;96(3):303-308

  Skin Lamellar Bodies are not Discrete Vesicles but Part of a Tubuloreticular Network

  den Hollander L; Han H; de Winter M; Svensson L; Masich S; Daneholt B; Norlen L
• Article: LAKARTIDNINGEN. 2016;113:DTAF

  [Acute cutaneous symptom complex with subsequent cataract. The internet drug MT-45 may be the cause].

  Bradley M; Hasselblad A; Norlen L; Lapins J; Bäckberg M; Helander A
• Article: JOURNAL OF CLINICAL INVESTIGATION. 2015;125(8):3008-3026

  MicroRNA-132 enhances transition from inflammation to proliferation during wound healing

  Li D; Wang A; Liu X; Meisgen F; Gruenler J; Botusan IR; Narayanan S; Erikci E; Li X; Blomqvist L; Du L; Pivarcsi A; Sonkoly E; Chowdhury K; Catrina S-B; Stahle M; Landen NX
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2015;135(6):1676-1685

  MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration

  Li D; Li X; Wang A; Meisgen F; Pivarcsi A; Sonkoly E; Stahle M; Landen NX
• Review: BRITISH JOURNAL OF DERMATOLOGY. 2014;171:13-18

  Update of technologies for examining the stratum corneum at the molecular level

  Norlen L
• Article: EXPERIMENTAL DERMATOLOGY. 2014;23(9):620-624

  Genetic polymorphisms altering microRNA activity in psoriasis - a key to solve the puzzle of missing heritability?

  Pivarcsi A; Stahle M; Sonkoly E
• Article: MOLECULAR ONCOLOGY. 2014;8(5):912-926

  Identification of novel non-coding RNA-based negative feedback regulating the expression of the oncogenic transcription factor GLI1

  Villegas VE; Rahman MF-U; Fernandez-Barrena MG; Diao Y; Liapi E; Sonkoly E; Stahle M; Pivarcsi A; Annaratone L; Sapino A; Ramirez Clavijo S; Burglin TR; Shimokawa T; Ramachandran S; Kapranov P; Fernandez-Zapico ME; Zaphiropoulos PG
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2014;134(7):1931-1940

  MiR-146a Negatively Regulates TLR2-Induced Inflammatory Responses in Keratinocytes

  Meisgen F; Landen NX; Wang A; Rethi B; Bouez C; Zuccolo M; Gueniche A; Stahle M; Sonkoly E; Breton L; Pivarcsi A
• Article: CARCINOGENESIS. 2014;35(5):1110-1120

  miR-193b/365a cluster controls progression of epidermal squamous cell carcinoma

  Gastaldi C; Bertero T; Xu N; Bourget-Ponzio I; Lebrigand K; Fourre S; Popa A; Cardot-Leccia N; Meneguzzi G; Sonkoly E; Pivarcsi A; Mari B; Barbry P; Ponzio G; Rezzonico R
• Article: EXPERIMENTAL DERMATOLOGY. 2014;23(4):281-283

  Activation of Toll-like receptors alters the microRNA expression profile of keratinocytes

  Meisgen F; Landen NX; Bouez C; Zuccolo M; Gueniche A; Stahle M; Sonkoly E; Breton L; Pivarcsi A
• Article: PLOS ONE. 2014;9(7):e103206

  MicroRNA-31 Is Overexpressed in Cutaneous Squamous Cell Carcinoma and Regulates Cell Motility and Colony Formation Ability of Tumor Cells

  Wang A; Landen NX; Meisgen F; Lohcharoenkal W; Stahle M; Sonkoly E; Pivarcsi A
• Article: BRITISH JOURNAL OF DERMATOLOGY. 2013;169(3):563-570

  Changes in the level of serum microRNAs in patients with psoriasis after antitumour necrosis factor- therapy

  Pivarcsi A; Meisgen F; Xu N; Stahle M; Sonkoly E
• Article: JOURNAL OF DERMATOLOGICAL SCIENCE. 2013;71(1):12-21

  The chemokine receptor CCR3 participates in tissue remodeling during atopic skin inflammation

  Gaspar K; Kukova G; Bunemann E; Buhren BA; Sonkoly E; Szollosi AG; Muller A; Savinko T; Lauerma AI; Alenius H; Kemeny L; Dieu-Nosjean M-C; Stander S; Fischer JW; Ruzicka T; Zlotnik A; Szegedi A; Homey B
• Letter: ACTA DERMATO-VENEREOLOGICA. 2013;93(3):366-367

  Are BIC (miR-155) Polymorphisms Associated with Eczema Susceptibility?

  Saaf A; Kockum I; Wahlgren C-F; Xu N; Sonkoly E; Stahle M; Nordenskjold M; Bradley M; Pivarcsi A
• Published conference paper: EUROPEAN JOURNAL OF DERMATOLOGY. 2013;23:66-71

  Interleukin-8 is regulated by miR-203 at the posttranscriptional level in primary human keratinocytes

  Wei T; Xu N; Meisgen F; Stahle M; Sonkoly E; Pivarcsi A
• Article: RNA BIOLOGY. 2013;10(2):321-333

  RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling

  Shimokawa T; Rahman MF-U; Tostar U; Sonkoly E; Stahle M; Pivarcsi A; Palaniswamy R; Zaphiropoulos PG
• Article: JOURNAL OF IMMUNOLOGY. 2013;190(2):678-688

  MicroRNA-31 Is Overexpressed in Psoriasis and Modulates Inflammatory Cytokine and Chemokine Production in Keratinocytes via Targeting Serine/Threonine Kinase 40

  Xu N; Meisgen F; Butler LM; Han G; Wang X-J; Soderberg-Naucler C; Stahle M; Pivarcsi A; Sonkoly E
• Article: SKIN PHARMACOLOGY AND PHYSIOLOGY. 2013;26(4-6):213-216

  Current Understanding of Skin Barrier Morphology

  Norlen L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2012;132(9):2215-2225

  The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety

  Iwai I; Han H; den Hollander L; Svensson S; Oefverstedt L-G; Anwar J; Brewer J; Bloksgaard M; Laloeuf A; Nosek D; Masich S; Bagatolli LA; Skoglund U; Norlen L
• Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(35):29899-29908

  MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion

  Xu N; Zhang L; Meisgen F; Harada M; Heilborn J; Homey B; Grander D; Stahle M; Sonkoly E; Pivarcsi A
• Article: EXPERIMENTAL DERMATOLOGY. 2012;21(4):312-314

  MiR-21 is uip-regulated n psoriasis and suppresses T cell apoptosis

  Meisgen F; Xu N; Wei T; Janson PC; Obad S; Broom O; Nagy N; Kauppinen S; Kemeny L; Stahle M; Pivarcsi A; Sonkoly E
• Article: ONCOGENESIS. 2012;1(3):e3

  MicroRNA-203 functions as a tumor suppressor in basal cell carcinoma

  Sonkoly E; Loven J; Xu N; Meisgen F; Wei T; Brodin P; Jaks V; Kasper M; Shimokawa T; Harada M; Heilborn J; Hedblad M-A; Hippe A; Grander D; Homey B; Zaphiropoulos PG; Arsenian-Henriksson M; Stahle M; Pivarcsi A
• Article: ARCHIVES OF DERMATOLOGICAL RESEARCH. 2011;303(10):745-752

  Comparison of stress-induced PRINS gene expression in normal human keratinocytes and HaCaT cells.

  Bari L; Bacsa S; Sonkoly E; Bata-Csörgo Z; Kemény L; Dobozy A; Széll M
• Review: MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS. 2011;717(1-2):46-53

  MicroRNAs in inflammation and response to injuries induced by environmental pollution

  Sonkoly E; Pivarcsi A
• Article: ANTICANCER RESEARCH. 2011;31(10):3151-3157

  Cyclin B1 Expression and p53 Status in Squamous Cell Carcinomas of the Head and Neck

  Hoffmann TK; Trellakis S; Okulicz K; Schuler P; Greve J; Arnolds J; Bergmann C; Bas M; Lang S; Lehnerdt G; Brandau S; Mattheis S; Scheckenbach K; Finn OJ; Whiteside TL; Sonkoly E
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2011;131(7):1521-1529

  MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2

  Xu N; Brodin P; Wei T; Meisgen F; Eidsmo L; Nagy N; Kemeny L; Stahle M; Sonkoly E; Pivarcsi A
• Article: SKIN PHARMACOLOGY AND PHYSIOLOGY. 2011;24(4):190-198

  Sorption Properties of the Human Stratum Corneum

  Johnsen GK; Norlen L; Martinsen OG; Grimnes S
• Letter: EXPERIMENTAL DERMATOLOGY. 2010;19(9):854-856

  The expression of microRNA-203 during human skin morphogenesis

  Wei T; Orfanidis K; Xu N; Janson P; Stahle M; Pivarcsi A; Sonkoly E
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2010;126(3):581-9.e1-20-U306

  MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4

  Sonkoly E; Janson P; Majuri M-L; Savinko T; Fyhrquist N; Eidsmo L; Xu N; Meisgen F; Wei T; Bradley M; Stenvang J; Kauppinen S; Alenius H; Lauerma A; Homey B; Winqvist O; Stahle M; Pivarcsi A
• Article: EXPERIMENTAL DERMATOLOGY. 2010;19(3):269-278

  The anti-apoptotic protein G1P3 is overexpressed in psoriasis and regulated by the non-coding RNA, PRINS.

  Szegedi K; Sonkoly E; Nagy N; Németh IB; Bata-Csörgo Z; Kemény L; Dobozy A; Széll M
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2010;130(1):124-134

  Protein Kinase C-Dependent Upregulation of miR-203 Induces the Differentiation of Human Keratinocytes

  Sonkoly E; Wei T; Lorie EP; Suzuki H; Kato M; Torma H; Stahle M; Pivarcsi A
• Review: INTERNATIONAL REVIEWS OF IMMUNOLOGY. 2009;28(6):535-561

  microRNAs in Inflammation

  Sonkoly E; Pivarcsi A
• Article: JOURNAL OF MICROSCOPY. 2009;235(3):293-307

  Molecular cryo-electron tomography of vitreous tissue sections: current challenges

  Norlen L; Oktem O; Skoglund U
• Article: INTERNATIONAL JOURNAL OF CANCER. 2009;124(11):2589-2596

  A novel mechanism for anti-EGFR antibody action involves chemokine-mediated leukocyte infiltration

  Hoffmann TK; Schirlau K; Sonkoly E; Brandau S; Lang S; Pivarcsi A; Balz V; Mueller A; Homey B; Boelke E; Reichert T; Friebe-Hoffmann U; Greve J; Schuler P; Scheckenbach K; Schipper J; Bas M; Whiteside TL; Bier H
• Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2009;13(1):24-38

  Advances in microRNAs: implications for immunity and inflammatory diseases

  Sonkoly E; Pivarcsi A
• Review: INTERNATIONAL JOURNAL OF COSMETIC SCIENCE. 2008;30(6):391-411

  Stratum corneum lipid organization as observed by atomic force, confocal and two-photon excitation fluorescence microscopy.

  Norlén L; Plasencia I; Bagatolli L
• Article: ORAL ONCOLOGY. 2008;44(12):1100-1109

  Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.

  Hoffmann TK; Sonkoly E; Hauser U; van Lierop A; Whiteside TL; Klussmann JP; Hafner D; Schuler P; Friebe-Hoffmann U; Scheckenbach K; Erjala K; Grénman R; Schipper J; Bier H; Balz V
• Review: EUROPEAN JOURNAL OF DERMATOLOGY. 2008;18(3):279-284

  Exploring skin structure using cryo-electron microscopy and tomography

  Norlen L
• Review: CLINICAL AND EXPERIMENTAL DERMATOLOGY. 2008;33(3):312-315

  MicroRNAs: novel regulators in skin inflammation

  Sonkoly E; Stahle M; Pivarcsi A
• Review: SEMINARS IN CANCER BIOLOGY. 2008;18(2):131-140

  MicroRNAs and immunity:: Novel players in the regulation of normal immune function and inflammation

  Sonkoly E; Stahle M; Pivarcsi A
• Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2007;104(48):19055-19060

  Tumor immune escape by the loss of homeostatic chemokine expression

  Pivarcsi A; Mueller A; Hippe A; Rieker J; van Lierop A; Steinhoff M; Seeliger S; Kubitza R; Pippirs U; Meller S; Gerber PA; Liersch R; Buenemann E; Sonkoly E; Wiesner U; Hoffmann TK; Schneider L; Piekorz R; Enderlein E; Reifenberger J; Rohr U-P; Haas R; Boukamp P; Haase I; Nuernberg B; Ruzicka T; Zlotnik A; Homey B
• Article: BIOPHYSICAL JOURNAL. 2007;93(9):3142-3155

  Direct visualization of lipid domains in human skin stratum corneum's lipid membranes: Effect of pH and temperature

  Plasencia I; Norlen L; Bagatolli LA
• Article: INTERNATIONAL JOURNAL OF COSMETIC SCIENCE. 2007;29(5):335-352

  Nanostructure of the stratum corneum extracellular lipid matrix as observed by cryo-electron microscopy of vitreous skin sections.

  Norlén L
• Article: PLOS ONE. 2007;2(7):e610

  MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis?

  Sonkoly E; Wei T; Janson PCJ; Saaf A; Lundeberg L; Tengvall-Linder M; Norstedt G; Alenius H; Homey B; Scheynius A; Stahle M; Pivarcsi A
• Review: EXPERIMENTAL CELL RESEARCH. 2007;313(10):2217-2227

  Structural analysis of vimentin and keratin intermediate filaments by cryo-electron tomography

  Norlen L; Masich S; Goldie KN; Hoenger A
• Article: JOURNAL OF STRUCTURAL BIOLOGY. 2007;158(3):386-400

  Human stratum corneum lipid organization as observed by atomic force microscopy on Langmuir-Blodgett films

  Norlen L; Gil IP; Simonsen A; Descouts P
• Article: HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK. 2007;29(5):472-478

  Aberrant cytokine expression in serum of patients with adenoid cystic carcinoma and squamous cell carcinoma of the head and neck.

  Hoffmann TK; Sonkoly E; Homey B; Scheckenbach K; Gwosdz C; Bas M; Chaker A; Schirlau K; Whiteside TL
• Article: INTERNATIONAL JOURNAL OF COSMETIC SCIENCE. 2006;28(6):397-425

  Stratum corneum keratin structure, function and formation - a comprehensive review.

  Norlén L
• Article: JOURNAL OF STRUCTURAL BIOLOGY. 2006;156(3):461-468

  A procedure to deposit fiducial markers on vitreous cryo-sections for cellular tomography

  Masich S; Ostberg T; Norlen L; Shupliakov O; Daneholt B
• Article: GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. 2006;244(6):717-724

  Vesicular stomatitis virus induces apoptosis in the Wong-Kilbourne derivative of the Chang conjunctival cell line.

  Gallyas E; Seprényi G; Sonkoly E; Mándi Y; Kemény L; Megyeri K
• Article: INTERNATIONAL JOURNAL OF CANCER. 2006;118(9):2147-2157

  Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy.

  Muller A; Sonkoly E; Eulert C; Gerber PA; Kubitza R; Schirlau K; Franken-Kunkel P; Poremba C; Snyderman C; Klotz L-O; Ruzicka T; Bier H; Zlotnik A; Whiteside TL; Homey B; Hoffmann TK
• Letter: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2006;20(5):629-630

  The identification of primary human herpesvirus 7 infection in young adults with pityriasis rosea by investigating avidity of antibodies.

  Chuh AAT; Kempf W
• Article: JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. 2006;117(2):411-417

  IL-31: A new link between T cells and pruritus in atopic skin inflammation

  Sonkoly E; Muller A; Lauerma AI; Pivarcsi A; Soto H; Kemeny L; Alenius H; Dieu-Nosjean MC; Meller S; Rieker J; Steinhoff M; Hoffmann TK; Ruzicka T; Zlotnik A; Homey B
• Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(25):24159-24167

  Identification and characterization of a novel, psoriasis susceptibility-related noncoding RNA gene, PRINS

  Sonkoly E; Bata-Csorgo Z; Pivarcsi A; Polyanka H; Kenderessy-Szabo A; Molnar G; Szentpali K; Bari L; Megyeri K; Mandi Y; Dobozy A; Kemeny L; Szell M
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2005;124(4):764-777

  Nanostructure of the epidermal extracellular space as observed by cryo-electron microscopy of vitreous sections of human skin

  Al-Amoudi A; Dubochet J; Norlén L
• Letter: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2004;18(6):738-740

  Avidity of antibodies to human herpesvirus 7 suggests primary infection in young adults with pityriasis rosea.

  Vág T; Sonkoly E; Kárpáti S; Kemény B; Ongrádi J
• Article: JOURNAL OF IMMUNOLOGY. 2004;173(9):5810-5817

  CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure

  Pivarcsi A; Gombert M; Dieu-Nosjean MC; Lauerma A; Kubitza R; Meller S; Rieker J; Muller A; Da Cunha L; Haahtela A; Sonkoly E; Fridman WH; Alenius H; Kemeny L; Ruz'icka T; Zlotnik A; Homey B
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2004;123(4):715-732

  Stratum corneum keratin structure, function, and formation:: The cubic rod-packing and membrane templating model

  Norlén L; Al-Amoudi A
• Letter: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. 2004;18(5):639-641

  Familiar occurrence of papular-purpuric 'gloves and socks' syndrome with human herpes virus-7 and human parvovirus B19 infection.

  Vág T; Sonkoly E; Kemény B; Kárpáti S; Horváth A; Ongrádi J
• Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(7):5621-5629

  Role for ELOVL3 and fatty acid chain length in development of hair and skin function

  Westerberg R; Tvrdik P; Undén AB; Månsson JE; Norlén L; Jakobsson A; Holleran WH; Elias PM; Asadi A; Flodby P; Toftgård R; Capecchi MR; Jacobsson A
• Article: ORVOSI HETILAP. 2003;144(33):1623-1629

  [Studies on the novel association of human herpesvirus-7 with skin diseases].

  Vág T; Sonkoly E; Kemény B; Kárpáti S; Horváth A; Ongrádi J
• Article: SKIN PHARMACOLOGY AND APPLIED SKIN PHYSIOLOGY. 2003;16(4):203-211

  Molecular skin barrier models and some central problems for the understanding of skin barrier structure and function

  Norlén L
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2003;120(4):555-560

  A cryotransmission electron microscopy study of skin barrier formation

  Norlén L; Al-Amoudi A; Dubochet J
• Article: JOURNAL OF CONTROLLED RELEASE. 2000;63(1-2):213-226

  Structure-related aspects on water diffusivity in fatty acid-soap and skin lipid model systems

  Norlén L; Engblom J
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1999;113(4):533-540

  A new computer-based evaporimeter system for rapid and precise measurements of water diffusion through stratum corneum in vitro

  Norlén L; Engblom J; Andersson M; Forslind B
• Doctoral thesis: 1999

  The skin barrier : structure and physical function

  Norlén LPO
• Article: JOURNAL OF INVESTIGATIVE DERMATOLOGY. 1999;112(1):72-77

  Inter- and intra-individual differences in human stratum corneum lipid content related to physical parameters of skin barrier function in vivo

  Norlén L; Nicander I; Rozell BL; Ollmar S; Forslind B
• Article: SKIN RESEARCH AND TECHNOLOGY. 1998;4(4):213-221

  Electrical impedance and other physical parameters as related to lipid content of human stratum corneum.

  Nicander I; Norlen L; Brockstedt U; Rozell BL; Forslind B; Ollmar S
• Article: ARCHIVES OF DERMATOLOGICAL RESEARCH. 1998;290(9):508-516

  A new HPLC-based method for the quantitative analysis of inner stratum corneum lipids with special reference to the free fatty acid fraction

  Norlen L; Nicander I; Lundsjo A; Cronholm T; Forslind B
• Article: CURRENT PROBLEMS IN DERMATOLOGY. 1998;26:165-176

  Lipid content and electrical impedance

  Nicander I; Norlén L; Forslind B; Ollmar S
• Article: ARCHIVES OF DERMATOLOGICAL RESEARCH. 1997;289(9):506-513

  Stratum corneum swelling. Biophysical and computer assisted quantitative assessments

  Norlen L; Emilson A; Forslind B
• Article: JOURNAL OF DERMATOLOGICAL SCIENCE. 1997;14(2):115-125

  A novel approach to the understanding of human skin barrier function

  Forslind B; Engstrom S; Engblom J; Norlen L
• Show more

Staff and contact

Group leader

• 

  Enikö Sonkoly

  Senior Lecturer | Docent

  E-mail eniko.sonkoly@ki.se

All members of the group

• Jan Cedric Freisenhausen

  Phd Student

  E-mail jan.cedric.freisenhausen@ki.se
• 

  Longlong Luo

  Affiliated to Research

  E-mail longlong.luo@ki.se
• Lars Norlen

  Affiliated to Research | Docent

  Telephone +46852482806

  E-mail lars.norlen@ki.se
• 

  Enikö Sonkoly

  Senior Lecturer | Docent

  E-mail eniko.sonkoly@ki.se