The team's focus
In our team, we integrate various advanced experimental approaches to investigate disease-specific subpopulations of myeloid cells, especially of granulocytes, in blood and tissues from patients and healthy individuals.
Granulocytes are the first line of defense against pathogens. They initiate repair mechanisms of the damaged tissue but can occasionally cause severe tissue damage that could lead to chronic pathologies. Despite their importance in modulating adaptive immune responses, the phenotype and function of granulocyte subpopulations in human tissues and diseases are not well understood.
Currently, the team focuses on characterizing the granulocyte subpopulations in psoriasis, Langerhans cell histiocytosis and COVID-19 and understanding how the granulocytes communicate with other cells contributing to disease pathology. Our goal is to improve the diagnosis and treatment of patients.
Magdalini Lourda about her research
Magdalini Lourda in "Forskning och Framsteg"
Magdalini Lourda interviewed on ki.se
We always want to get in touch with talented potential co-workers. If you are interested in doing research in our team, either as a student or post-doc, contact the Team leader: email@example.com
- Elucidating the immunopathogenic mechanisms behind the development of Langerhans cell histiocytosis.
- Granulocyte phenotype and function in acute and chronic inflammatory diseases (eg COVID-19, psoriasis, inflammatory bowel disease).
- Daniel Hagey, Department of Laboratory Medicine.
- Samir El Andaloussi, Department of Laboratory Medicine.
- Ujjwal Neogi, Department of Laboratory Medicine.
- Susanna Brighenti, Center for Infectious Medicine.
Karolinska Institutet and others
- The Swedish Childhood Cancer Fund
- Dr Åke Olsson foundation for haematological research
- Karolinska Institutet
- Fredrik O Ingrid Thurings foundation
- Märta and Gunnar V Philipsons foundation