Endocrinology and Metabolism
Research into endocrinology and metabolism touches upon many of the most important health problems of our time, including diabetes, obesity, hypertension, osteoporosis and hormonal disturbances. The research involves e.g. nutrition, physical activity, anaesthesia and intensive care, drug metabolism, psychiatry, neurology, nephrology and gastroenterology.
Articles and features
Spotlight on Fat
The human body is very unwilling to let go of the fat that it has stored. Fighting obesity is thus essentially a battle against ourselves.
Spotlight on diabetes
Many pieces of the puzzle are still missing when it comes to understanding diabetes, but one thing is for sure – diabetes is not one disease but several.
More and more people with unusual diseases are diagnosed
In just a few years, researchers have obtained tools to diagnose a large number of diseases that were previously unknown. Now the hope is that this diagnostic revolution will also lead to new treatments.
Why some people become obese
Weight gain can, in some cases, be attributed to a reduced ability to metabolise fat, according to Professor Mikael Rydén and colleagues. The researchers are now developing means of measuring the ability to break down fat.
News in Endocrinology and Metabolism
Some of our professors in the area
Researching health effects of nitrogen oxides
Mattias Carlström researches the beneficial effects of nitric oxide on the body, including the cardiovascular system and kidneys, in order to understand the biological mechanisms and pave the way for the clinical use of different forms of nitrate that can increase concentrations of nitric oxide.
Studying the relationship between exercise and health
While exercise is good for us, we still do not fully understand why. Jorge Ruas is researching the nature of this connection at a molecular and genetic level in the hope of contributing to the development of better therapies.
Better use of drugs in low-income countries
Guidelines for treatment are often established based on drug development and research performed in relation to the Western world. Eleni Aklillu wants to contribute to the appropriate use of drugs adapted for conditions in sub-Saharan Africa.
The pathogenic mechanisms of type 1 diabetes
Malin Flodström Tullberg researches on the link between enteroviruses and type 1 diabetes. She also hopes to be able to contribute to a new enterovirus vaccine.
Reducing the risk of cardiovascular disease in diabetes
Thomas Nyström is studying the risk of cardiovascular disease in patients with diabetes. He is especially interested in the intestinal hormone GLP-1, its use and effects.
Focusing on diabetes and its complications
During her long research career, Kerstin Brismar has been focusing on both growth factors and complications in diabetes. She has especially been interested in the regulation of the IGF-IGFBP system, oxidative stress, and cellular effects of high glucose.
He is a research leader on three continents
Per-Olof Berggren is Professor of Experimental Endocrinology at KI’s Department of Molecular Medicine and Surgery. He is also active as a research leader in the United States and in Singapore.
Bariatric surgery in pregnancy, delivery and child health
The use of bariatric surgery has increased dramatically in recent decades. Martin Neovius is studying how effective this type of surgery is, its associated risks and its cost effectiveness.
Reveling kidney disease at an early stage
Johan Ärnlöv is studying kidney disease and its relationship with cardiovascular disease. He is involved in international consortiums that are mapping kidney disease globally.
Seeking new ways to diagnose and treat Alzheimer’s
Angel Cedazo-Minguez wants to understand how the metabolism of cholesterol and insulin in the brain contributes to the onset of Alzheimer’s disease. In the long-term, he hopes to develop new diagnostic methods and treatments before the disease gives symptoms.