Peter Swoboda

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Articles

Article: BMC BIOLOGY. 2024;22(1):48
Primary cilia promote the differentiation of human neurons through the WNT signaling pathway
Coschiera A; Yoshihara M; Lauter G; Ezer S; Pucci M; Li H; Kavsek A; Riedel CG; Kere J; Swoboda P
Article: ELIFE. 2023;12:e89702
Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans
Brocal-Ruiz R; Esteve-Serrano A; Mora-Martinez C; Luisa Franco-Rivadeneira M; Swoboda P; Tena JJ; Vilar M; Flames N
Article: METHODS IN CELL BIOLOGY. 2023;176:27-41
Human LUHMES and NES cells as models for studying primary cilia in neurons.
Coschiera A; Watts ME; Kere J; Tammimies K; Swoboda P
Article: CELL REPORTS. 2022;39(2):110661
The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization
Ahn S; Yang H; Son S; Lee HS; Park D; Yim H; Choi H-J; Swoboda P; Lee J
Article: JOURNAL OF CELL SCIENCE. 2020;133(21):jcs249789
Differentiation of ciliated human midbrain-derived LUHMES neurons
Lauter G; Coschiera A; Yoshihara M; Sugiaman-Trapman D; Ezer S; Sethurathinam S; Katayama S; Kere J; Swoboda P
Article: REDOX BIOLOGY. 2019;24:101178
Redox-dependent and redox-independent functions of Caenorhabditis elegans thioredoxin 1
Sanzo-Machuca A; Monje Moreno JM; Casado-Navarro R; Karakuzu O; Guerrero-Gomez D; Fierro-Gonzalez JC; Swoboda P; Munoz MJ; Garsin DA; Pedrajas JR; Barrios A; Miranda-Vizuete A
Article: NATURE COMMUNICATIONS. 2018;9(1):4400
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
Lin X-X; Sen I; Janssens GE; Zhou X; Fonslow BR; Edgar D; Stroustrup N; Swoboda P; Yates JRIII; Ruvkun G; Riedel CG
Article: BMC GENOMICS. 2018;19(1):181
Characterization of the human RFX transcription factor family by regulatory and target gene analysis
Sugiaman-Trapman D; Vitezic M; Jouhilahti E-M; Mathelier A; Lauter G; Misra S; Daub CO; Kere J; Swoboda P
Article: GENETICS. 2018;208(3):1083-1097
An Expanded Role for the RFX Transcription Factor DAF-19, with Dual Functions in Ciliated and Nonciliated Neurons
De Stasio EA; Mueller KP; Bauer RJ; Hurlburt AJ; Bice SA; Scholtz SL; Phirke P; Sugiaman-Trapman D; Stinson LA; Olson HB; Vogel SL; Ek-Vazquez Z; Esemen Y; Korzynski J; Wolfe K; Arbuckle BN; Zhang H; Lombard-Knapp G; Piasecki BP; Swoboda P
Article: THE FASEB JOURNAL. 2016;30(10):3578-3587
Ciliary dyslexia candidate genes DYX1C1 and DCDC2 are regulated by Regulatory Factor X (RFX) transcription factors through X-box promoter motifs
Tammimies K; Bieder A; Lauter G; Sugiaman-Trapman D; Torchet R; Hokkanen M-E; Burghoorn J; Castren E; Kere J; Tapia-Paez I; Swoboda P
Article: GENETICS. 2016;203(1):387-402
TRX-1 Regulates SKN-1 Nuclear Localization Cell Non-autonomously in Caenorhabditis elegans
McCallum KC; Liu B; Fierro-Gonzalez JC; Swoboda P; Arur S; Miranda-Vizuete A; Garsin DA
Article: JOURNAL OF NEUROSCIENCE. 2016;36(11):3157-3169
Neuropeptidergic Signaling and Active Feeding State Inhibit Nociception in Caenorhabditis elegans
Ezcurra M; Walker DS; Beets I; Swoboda P; Schafer WR
Article: GENETICS. 2015;200(1):123-134
Cis- and Trans-Regulatory Mechanisms of Gene Expression in the ASJ Sensory Neuron of Caenorhabditis elegans
Gonzalez-Barrios M; Fierro-Gonzalez JC; Krpelanova E; Antonio Mora-Lorca J; Rafael Pedrajas J; Penate X; Chavez S; Swoboda P; Jansen G; Miranda-Vizuete A
Article: CILIA. 2015;4:5
The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies.
Benmerah A; Durand B; Giles RH; Harris T; Kohl L; Laclef C; Meilhac SM; Mitchison HM; Pedersen LB; Roepman R; Swoboda P; Ueffing M; Bastin P
Article: PLOS ONE. 2015;10(2):e0116702
ABCE1 Is a Highly Conserved RNA Silencing Suppressor
Kaerblane K; Gerassimenko J; Nigul L; Piirsoo A; Smialowska A; Vinkel K; Kylsten P; Ekwall K; Swoboda P; Truve E; Sarmiento C
Article: AGING. 2014;6(11):975-991
Iron promotes protein insolubility and aging in C. elegans
Klang IM; Schilling B; Sorensen DJ; Sahu AK; Kapahi P; Andersen JK; Swoboda P; Killilea DW; Gibson BW; Lithgow GJ
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2014;73:328-336
Protective effects of the thioredoxin and glutaredoxin systems in dopamine-induced cell death
Arodin L; Miranda-Vizuete A; Swoboda P; Fernandes AP
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2014;68(100):205-219
Functional characterization of thioredoxin 3 (TRX-3), a Caenorhabditis elegans intestine-specific thioredoxin
Jimenez-Hidalgo M; Kurz CL; Rafael Pedrajas J; Jose Naranjo-Galindo F; Gonzalez-Barrios M; Cabello J; Saez AG; Lozano E; Button EL; Veal EA; Fierro-Gonzalez JC; Swoboda P; Miranda-Vizuete A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;444(2):254-259
RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe
Smialowska A; Djupedal I; Wang J; Kylsten P; Swoboda P; Ekwall K
Article: DEVELOPMENTAL BIOLOGY. 2012;368(2):415-426
The in vivo dissection of direct RFX-target gene promoters in C. elegans reveals a novel cis-regulatory element, the C-box
Burghoorn J; Piasecki BP; Crona F; Phirke P; Jeppsson KE; Swoboda P
Article: ANTIOXIDANTS AND REDOX SIGNALING. 2012;16(12):1384-1400
The Characterization of the Caenorhabditis elegans Mitochondrial Thioredoxin System Uncovers an Unexpected Protective Role of Thioredoxin Reductase 2 in β-Amyloid Peptide Toxicity
Cacho-Valadez B; Munoz-Lobato F; Rafael Pedrajas J; Cabello J; Carlos Fierro-Gonzalez J; Navas P; Swoboda P; Link CD; Miranda-Vizuete A
Article: CURRENT BIOLOGY. 2011;21(20):1685-1694
The Tubulin Deglutamylase CCPP-1 Regulates the Function and Stability of Sensory Cilia in C. elegans
O'Hagan R; Piasecki BP; Silva M; Phirke P; Nguyen KCQ; Hall DH; Swoboda P; Barr MM
Article: DEVELOPMENTAL BIOLOGY. 2011;357(1):235-247
Transcriptional profiling of C. elegans DAF-19 uncovers a ciliary base-associated protein and a CDK/CCRK/LF2p-related kinase required for intraflagellar transport
Phirke P; Efimenko E; Mohan S; Burghoorn J; Crona F; Bakhoum MW; Trieb M; Schuske K; Jorgensen EM; Piasecki BP; Leroux MR; Swoboda P
Article: SCIENCE. 2011;332(6032):930-936
Comparative Functional Genomics of the Fission Yeasts
Rhind N; Chen Z; Yassour M; Thompson DA; Haas BJ; Habib N; Wapinski I; Roy S; Lin MF; Heiman DI; Young SK; Furuya K; Guo Y; Pidoux A; Chen HM; Robbertse B; Goldberg JM; Aoki K; Bayne EH; Berlin AM; Desjardins CA; Dobbs E; Dukaj L; Fan L; FitzGerald MG; French C; Gujja S; Hansen K; Keifenheim D; Levin JZ; Mosher RA; Mueller CA; Pfiffner J; Priest M; Russ C; Smialowska A; Swoboda P; Sykes SM; Vaughn M; Vengrova S; Yoder R; Zeng Q; Allshire R; Baulcombe D; Birren BW; Brown W; Ekwall K; Kellis M; Leatherwood J; Levin H; Margalit H; Martienssen R; Nieduszynski CA; Spatafora JW; Friedman N; Dalgaard JZ; Baumann P; Niki H; Regev A; Nusbaum C
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2011;406(3):478-482
The thioredoxin TRX-1 regulates adult lifespan extension induced by dietary restriction in Caenorhabditis elegans
Carlos Fierro-Gonzalez J; Gonzalez-Barrios M; Miranda-Vizuete A; Swoboda P
Article: EMBO JOURNAL. 2011;30(6):1110-1122
Food sensitizes C. elegans avoidance behaviours through acute dopamine signalling
Ezcurra M; Tanizawa Y; Swoboda P; Schafer WR
Article: PLOS ONE. 2011;6(1):e16561
The Thioredoxin TRX-1 Modulates the Function of the Insulin-Like Neuropeptide DAF-28 during Dauer Formation in Caenorhabditis elegans
Fierro-Gonzalez JC; Cornils A; Alcedo J; Miranda-Vizuete A; Swoboda P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2011;108(3):1064-1069
Selenoprotein TRXR-1 and GSR-1 are essential for removal of old cuticle during molting in Caenorhabditis elegans
Stenvall J; Fierro-Gonzalez JC; Swoboda P; Saamarthy K; Cheng Q; Cacho-Valadez B; Arner ESJ; Persson OP; Miranda-Vizuete A; Tuck S
Article: PLOS ONE. 2011;6(6):e20580
Increased Expression of the Dyslexia Candidate Gene DCDC2 Affects Length and Signaling of Primary Cilia in Neurons
Massinen S; Hokkanen M-E; Matsson H; Tammimies K; Tapia-Paez I; Dahlstrom-Heuser V; Kuja-Panula J; Burghoorn J; Jeppsson KE; Swoboda P; Peyrard-Janvid M; Toftgard R; Castren E; Kere J
Article: PLOS ONE. 2011;6(6):e20995
The Retrograde IFT Machinery of C. elegans Cilia: Two IFT Dynein Complexes?
Hao L; Efimenko E; Swoboda P; Scholey JM
Article: GENETICS. 2010;186(3):969-982
Genetics of Extracellular Matrix Remodeling During Organ Growth Using the Caenorhabditis elegans Pharynx Model
Jafari G; Burghoorn J; Kawano T; Mathew M; Morck C; Axang C; Ailion M; Thomas JH; Culotti JG; Swoboda P; Pilon M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2010;107(29):12969-12974
Regulatory Factor X (RFX)-mediated transcriptional rewiring of ciliary genes in animals
Piasecki BP; Burghoorn J; Swoboda P
Article: JOURNAL OF CELL SCIENCE. 2010;123(12):2077-2084
Dauer pheromone and G-protein signaling modulate the coordination of intraflagellar transport kinesin motor proteins in C. elegans
Burghoorn J; Dekkers MPJ; Rademakers S; de Jong T; Willemsen R; Swoboda P; Jansen G
Article: GENETICS. 2009;183(2):595-3SI
Worms With a Single Functional Sensory Cilium Generate Proper Neuron-Specific Behavioral Output
Senti G; Ezcurra M; Lobner J; Schafer WR; Swoboda P
Article: MOLECULAR BIOLOGY OF THE CELL. 2008;19(12):5517-5528
Distinct Isoforms of the RFX Transcription Factor DAF-19 Regulate Ciliogenesis and Maintenance of Synaptic Activity
Senti G; Swoboda P
Article: PLOS GENETICS. 2008;4(3):e1000044
An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes
Li C; Inglis PN; Leitch CC; Efimenko E; Zaghloul NA; Mok CA; Davis EE; Bialas NJ; Healey MP; Heon E; Zhen M; Swoboda P; Katsanis N; Leroux MR
Article: GENOME BIOLOGY. 2007;8(9):R195
Identification of novel regulatory factor X (RFX) target genes by comparative genomics in Drosophila species
Laurencon A; Dubruille R; Efimenko E; Grenier G; Bissett R; Cortier E; Rolland V; Swoboda P; Durand B
Article: MOLECULAR BIOLOGY OF THE CELL. 2006;17(11):4801-4811
Caenorhabditis elegans DYF-2, an orthologue of human WDR19, is a component of the intraflagellar transport machinery in sensory Cilia
Efimenko E; Blacque OE; Ou G; Haycraft CJ; Yoder BK; Scholey JM; Leroux MR; Swoboda P
Article: FEBS LETTERS. 2006;580(2):484-490
Lifespan decrease in a Caenorhabditis elegans mutant lacking TRX-1, a thioredoxin expressed in ASJ sensory neurons
Miranda-Vizuete A; González JCF; Gahmon G; Burghoorn J; Navas P; Swoboda P
Article: GENOME BIOLOGY. 2006;7(12):R126
Identification of ciliary and ciliopathy genes in Caenorhabditis elegans through comparative genomics
Chen N; Mah A; Blacque OE; Chu J; Phgora K; Bakhoum MW; Newbury CRH; Khattra J; Chan S; Go A; Efimenko E; Johnsen R; Phirke P; Swoboda P; Marra M; Moerman DG; Leroux MR; Baillie DL; Stein LD
Article: JOURNAL OF CELL SCIENCE. 2005;118(23):5575-5587
The C-elegans homologs of nephrocystin-1 and nephrocystin-4 are cilia transition zone proteins involved in chemosensory perception
Winkelbauer ME; Schafer JC; Haycraft CJ; Swoboda P; Yoder BK
Article: CURRENT BIOLOGY. 2005;15(10):935-941
Functional genomics of the cilium, a sensory organelle
Blacque OE; Perens EA; Boroevich KA; Inglis PN; Li CM; Warner A; Khattra J; Holt RA; Ou GS; Mah AK; McKay SJ; Huang P; Swoboda P; Jones SJM; Marra MA; Baillie DL; Moerman DG; Shaham S; Leroux MR
Article: DEVELOPMENT. 2005;132(8):1923-1934
Analysis of xbx genes in C-elegans
Efimenko E; Bubb K; Mak HY; Holzman T; Leroux MR; Ruvkun G; Thomas JH; Swoboda P
Article: MOLECULAR BIOLOGY OF THE CELL. 2003;14(5):2057-2070
XBX-1 encodes a dynein light intermediate chain required for retrograde intraflagellar transport and cilia assembly in Caenorhabditis elegans
Schafer JC; Haycraft CJ; Thomas JH; Yoder BK; Swoboda P
Article: DEVELOPMENT. 2002;129(23):5487-5498
Drosophila regulatory factor X is necessary for ciliated sensory neuron differentiation
Dubruille R; Laurençon A; Vandaele C; Shishido E; Coulon-Bublex M; Swoboda P; Couble P; Kernan M; Durand B
Article: DEVELOPMENT. 2001;128(9):1493-1505
The C-elegans homolog of the murine cystic kidney disease gene Tg737 functions in a ciliogenic pathway and is disrupted in osm-5 mutant worms
Haycraft CJ; Swoboda P; Taulman PD; Thomas JH; Yoder BK
Article: MOLECULAR CELL. 2000;5(3):411-421
The RFX-type transcription factor DAF-19 regulates sensory neuron cilium formation in C. elegans
Swoboda P; Adler HT; Thomas JH
Article: PLANT MOLECULAR BIOLOGY. 1995;28(2):281-292
SOMATIC INTRACHROMOSOMAL HOMOLOGOUS RECOMBINATION EVENTS IN POPULATIONS OF PLANT SIBLINGS
PUCHTA H; SWOBODA P; GAL S; BLOT M; HOHN B
Article: THE PLANT JOURNAL. 1995;7(2):203-210
INDUCTION OF INTRACHROMOSOMAL HOMOLOGOUS RECOMBINATION IN WHOLE PLANTS
PUCHTA H; SWOBODA P; HOHN B
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All other publications

Review: DEVELOPMENT. 2014;141(7):1427-1441
Switching on cilia: transcriptional networks regulating ciliogenesis
Choksi SP; Lauter G; Swoboda P; Roy S
Review: METHODS IN ENZYMOLOGY. 2013;525:327-350
Finding Ciliary Genes: A Computational Approach
Henriksson J; Piasecki BP; Lend K; Burglin TR; Swoboda P
Meeting abstract: MECHANISMS OF DEVELOPMENT. 2009;126:S17
Worms with only a single cilium S.: per animal
Swoboda P
Editorial comment: GENOME BIOLOGY. 2008;9(6):312
Caenorhabditis elegans comes of age
Ceron J; Swoboda P

Employments

Principal Researcher, Department of Medicine, Huddinge, Karolinska Institutet, 2024-

Degrees and Education

Docent, Karolinska Institutet, 2018

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