Olof Hertting
Affiliated to Research | Docent
E-mail: olof.hertting@ki.se
Visiting address: CMM, L8, 17176 Stockholm
Postal address: K6 Kvinnors och barns hälsa, K6 Klinisk pediatrik Herlenius, 171 77 Stockholm
About me
Associate Professor and Teamleader for Paediatric infections at Karolinska Institutet and Consultant in paediatric infectious diseases at Karolinska University Hospital. My research is focusing on molecular immune responses in severe bacterial infections in children as well as epidemiological studies on children with a range of infectious diseases.
Research
Bone and Joint Infections in Children
Meningococcal infections in children and teenagers (the MEMPHIS study)Migration and health: targeting highly prevalent infections from Sub-Saharan Africa
Invasive Group A streptococcal infections in children
Articles
- Article: ACTA PAEDIATRICA. 2025;114(8):1825-1830Olsson-Åkefeldt S; Luthander J; Anmyr L; Villard L; Arnason S; Kemani MK; Wållgren E; Röstlund S; Tingborn M; Pettersson M; George E; Ryd-Rinder M; Hertting O
- Article: PEDIATRIC RESEARCH. 2024;96(2):319-324Brackel CLH; Noij LCE; Vijverberg SJH; Legghe CL; van der Zee AH; van Goudoever JB; Buonsenso D; Munblit D; Sigfrid L; Mcfarland S; Anmyr L; Ashkenazi-Hoffnung L; Bellinat APN; Dias NLS; Edwards A; Fashina T; Juraski RG; Goncalves ALN; Hansted E; Herczeg V; Hertting O; Jankauskaite LN; Kaswandani N; Kevalas R; Krivacsy P; Lorenz M; Malone LA; Mcvoy M; Miller DW; Morrow AK; Nugawela MD; Oliveira CR; Oliveira PRS; Osmanov IM; Overmars IM; Paintsil E; Pereira SMP; Prawira Y; Putri ND; Ramos RCF; Rasche M; Ryd-Rinder M; De Rose C; Samitova E; Jovanovic TS; Say D; Scott JT; Shachar-Lavie I; Shafran R; Shmueli E; Snipaitiene A; Stephenson T; Tenai N; Tosif S; Turkalj M; Valentini P; Vasconcelos LRS; Villard L; Vilser D; Hashimoto S; Terheggen-Lagro SWJ
- Article: ACTA PAEDIATRICA. 2024;113(7):1679-1684Bennet R; Rinder MR; George E; Hertting O; Luthander J; Akefeldt SO; Hammas B; Allander T; Eriksson M
- Article: ARCHIVES OF DISEASE IN CHILDHOOD. 2024;109(2):152-157Anastasopoulou S; Svensson E; Wickstroem R; Hertting O; Rinder MR; Bennet R; Eriksson M
- Article: EUROSURVEILLANCE. 2024;29(3):2300193Bjorklund V; Saxen H; Hertting O; Carlsen ELM; Hoffmann S; Hakansson S; Thors VS; Haraldsson A; Brigtsen AK; Dollner H; Huhtamaki H; Pokka T; Ruuska TS
- Article: RHINOLOGY. 2023;61(5):412-420Dennison SH; Granath A; Holmstrom M; Stjarne P; Hertting O
- Article: LANCET REGIONAL HEALTH-EUROPE. 2023;27:100581Wangdahl A; Bogale RT; Eliasson I; Broumou I; Faroogh F; Lind F; Vashchuk G; Hildell A; Franson S; Hallberg E; Grip I; Nordling I; Gervin A; Kaitoly S; Tekleab B; Wyss K; Requena-Mendez A; Hertting O; Farnert A
- Article: EUROSURVEILLANCE. 2022;27(7):2100079Requena-Mendez A; Mougkou A; Hedberg P; van der Werff SD; Tanushi H; Hertting O; Farnert A; Nyberg F; Naucler P
- Article: THORAX. 2022;77(2):154-163Hedberg P; Karlsson Valik J; van der Werff S; Tanushi H; Requena Mendez A; Granath F; Bell M; Martensson J; Dyrdak R; Hertting O; Farnert A; Ternhag A; Naucler P
- Article: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY. 2021;150:110866Dennison SH; Hertting O; Bennet R; Eriksson M; Holmstrom M; Ask LS; Lindstrand A; Dimitriou P; Stjarne P; Granath A
- Article: ACTA PAEDIATRICA. 2021;110(10):2802-2804Rhedin SA; Rinder MR; Hildenwall H; Herlenius E; Hertting O; Luthander J; Melen E; Nijman R; Olsson-Akefeldt S; Alfven T
- Article: EPIDEMIOLOGY & INFECTION. 2021;149:e126Sall O; Stenmark B; Jacobsson S; Eriksson L; Thulin Hedberg S; Hertting O; Fredlund H; Sundqvist M; Molling P
- Article: EUROPEAN JOURNAL OF PEDIATRICS. 2021;180(3):893-898Hertting O; Luthander J; Giske CG; Bennet R; Eriksson M
- Article: JOURNAL OF PAEDIATRICS AND CHILD HEALTH. 2020;56(12):1912-1917von Heideken J; Bennet R; Eriksson M; Hertting O
- Article: LAKARTIDNINGEN. 2020;117:19256Glans H; Hertting O
- Article: CELL AND TISSUE RESEARCH. 2020;380(3):669-673Mohanty S; Kamolvit W; Hertting O; Brauner A
- Article: ACTA PAEDIATRICA. 2019;108(12):2175-2185Wekell P; Hertting O; Holmgren D; Fasth A
- Article: ARCHIVES OF DISEASE IN CHILDHOOD-EDUCATION AND PRACTICE EDITION. 2019;104(5):235-243Wekell P; Hertting O; Holmgren D; Fasth A
- Article: INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY. 2019;121:50-54Dennison SH; Ask LS; Eriksson M; Granath A; Hertting O; Bennet R; Lindstrand A; Masaba P; Dimitriou P; Stjarne P
- Article: PLOS ONE. 2017;12(7):e0180810Hertting O; Luthje P; Sullivan D; Aspenstrom P; Brauner A
- Article: PEDIATRIC BLOOD & CANCER. 2017;64(7):e26397af Sandeberg M; Johansson E; Wettergren L; Bjork O; Hertting O; Nilsson A
- Journal article: 2017SEVERE PVL-POSITIVE BONE AND JOINT INFECTIONS IN CHILDREN – CASE SERIES AND CLINICAL CHARACTERISTICSHertting O
- Article: JOURNAL OF INFECTION. 2014;68:S151-S154Hertting O; Shingadia D
- Article: PLOS ONE. 2010;5(12):e15580Hertting O; Holm A; Luthje P; Brauner H; Dyrdak R; Jonasson AF; Wiklund P; Chromek M; Brauner A
- Article: TOXICON. 2008;51(8):1544-1547Hertting O; Chromek M; Slamova Z; Kadas L; Soderkvist M; Vainumae I; Tallvik T; Jacobson SH; Brauner A
- Article: PEDIATRIC RESEARCH. 2003;53(4):698-705Chromek M; Tullus K; Hertting O; Jaremko G; Khalil A; Li YH; Brauner A
- Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2003;131(2):225-233Hertting O; Khalil A; Jaremko G; Chromek M; Li YH; Bakhiet M; Bartfai T; Tullus K; Brauner A
- Article: PERITONEAL DIALYSIS INTERNATIONAL. 2003;23(1):5-13CAPD peritonitis induces the production of a novel peptide, daintain/allograft inflammatory factor-1Brauner A; Hertting O; Alkstrand E; Sandberg E; Chromek M; Chen ZW; Östenson CG
- Show more
All other publications
- Preprint: MEDRXIV. 2022Wångdahl A; Bogale RT; Eliasson I; Broumou I; Faroogh F; Lind F; Vashchuk G; Hildell A; Franson S; Hallberg E; Grip I; Nordling I; Gervin A; Kaitoly S; Tekleab B; Wyss K; Mendez AR; Hertting O; Färnert A
- Editorial comment: ACTA PAEDIATRICA. 2021;110(9):2578-2580Sterky E; Olsson-Akefeldt S; Hertting O; Herlenius E; Alfven T; Ryd Rinder M; Rhedin S; Hildenwall H
- Editorial comment: ACTA PAEDIATRICA. 2021;110(3):744-745Hertting O
- Letter: ACTA PAEDIATRICA. 2020;109(10):2152-2154Hildenwall H; Luthander J; Rhedin S; Hertting O; Olsson-Akefeldt S; Erik M; Alfven T; Herlenius E; Ryd Rinder M
- Letter: JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION. 2018;51(1):153-154Hertting O; Gremark O; Kallman O; Guler L; Bergstrom J
Grants
- Swedish Research Council1 January 2025 - 31 December 2026Malaria is a potentially severe and fatal disease. Artemisinin combination therapy (ACT) is the first line therapy for malaria. Alarming emergence of resistance to artemisinin and partner drugs is now reported from Sub-Saharan Africa. Understanding treatment outcomes and identifying drug resistant markers could guide management and development of new treatment strategies. The purpose of this preparatory study is to plan: 1) a nationwide prospective treatment efficacy study using a new standardized follow-up protocol for all malaria patients in Sweden for detecting treatment failures, and 2) to plan a comprehensive prospective study in adults treated for Plasmodium falciparum malaria with more extensive sampling to assess parasite clearance time in relation to antimalarial drug concentrations, host immunity and parasite genomics. Within the preparatory study, we will assess current practice of diagnostics and management of malaria across Sweden. Moreover, we will perform a retrospective review of treatment outcomes since ACT was introduced, and also perform a pilot analysis of resistance mutations in available archived samples. The project involves experts in infectious diseases, pediatrics, microbiology and pharmacologyand the aim is to establish a nationwide collaborative network including all treating clinics. The findings from this project will lead to improved management and monitoring of malaria in travelers, and could also inform treatment strategies in endemic areas.
- Swedish Research Council1 December 2023 - 30 November 2027Infections are an important part of migrant health. Detecting infections could prevent potentially severe acute and chronic conditions in migrants. Migration from countries in Sub-Saharan Africa has increased. Screening programmes therefore need to address infections that are highly prevalent in this region. Despite high parasite prevalence in endemic areas, malaria, schistosomiasis and strongyloides are not included in the current screening program for migrants and evidence-based guidelines are needed. In a recent study in Sweden, we detected an unexpectedly high malaria parasite prevalence in asymptomatic migrants screened at migrant health facilities with 9% prevalence overall, and up to 35% in children. Clinical observation when assessed for treatment, have detected health issues in parasite positive individuals. This project aims at establishing the need for a screening program, including exploring the parasite prevalence and health effects in migrants from Sub-Saharan Africa, as well as developing a diagnostic platform and time frame for screening. Moreover, we will perform a pilot clusterd randomised trial to assess the impact and feasibility of screening compared to standard of care without screening. Evaluation of introducing a screening program will include feasibility, acceptability and cost-effectiveness. The project has the potential to guide screening strategies and make significant contributions to improved health in migrants from Sub-Saharan Africa.
Employments
- Affiliated to Research, Department of Women's and Children's Health, Karolinska Institutet, 2025-2027
- Affiliated to Research, Department of Women's and Children's Health, Karolinska Institutet, 2024-2027
Degrees and Education
- Docent, Pediatrics, Karolinska Institutet, 2024
- Degree Of Doctor Of Philosophy, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2011
- University Medical Degree, Karolinska Institutet, 2000
Leadership and responsibility assignments
- Research team leader, Pediatric Infectious Diseases, Kvinnor och barns hälsa, Karolinska Institutet, 2025-