Zuzana Potacova

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Articles

Article: JOURNAL OF IMMUNOTHERAPY. 2017;40(4):132-139
A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer
Omazic B; Ayoglu B; Lohr M; Segersvard R; Verbeke C; Magalhaes I; Potacova Z; Mattsson J; Terman A; Ghazi S; Albiin N; Kartalis N; Nilsson P; Poiret T; Liu Z; Heuchel R; Schwenk JM; Permert J; Maeurer MJ; Ringden O
Article: PLOS ONE. 2017;12(11):e0187294
Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway
El-Serafi I; Terelius Y; Abedi-Valugerdi M; Naughton S; Saghafian M; Moshfegh A; Mattsson J; Potacova Z; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(4):676-681
Long-Term Follow-Up of Allogeneic Hematopoietic Stem Cell Transplantation for Solid Cancer
Omazic B; Remberger M; Barkholt L; Soderdahl G; Potacova Z; Wersall P; Ericzon B-G; Mattsson J; Ringden O
Article: TOXICOLOGY IN VITRO. 2015;29(7):1711-1719
Copper-based nanoparticles induce high toxicity in leukemic HL60 cells
Rodhe Y; Skoglund S; Wallinder IO; Potacova Z; Moller L
Article: PHARMACOGENOMICS JOURNAL. 2015;15(5):405-413
Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies
El-Serafi I; Fares M; Abedi-Valugerdi M; Afsharian P; Moshfegh A; Terelius Y; Potacova Z; Hassan M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;463(3):268-274
DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line
Fares M; Abedi-Valugerdi M; Hassan M; Potacova Z
Article: PLOS ONE. 2014;9(12):e114457
Cytotoxic Effects of Tetracycline Analogues (Doxycycline, Minocycline and COL-3) in Acute Myeloid Leukemia HL-60 Cells
Song H; Fares M; Maguire KR; Siden A; Potacova Z
Article: PLOS ONE. 2014;9(1):e86619
Cyclophosphamide Alters the Gene Expression Profile in Patients Treated with High Doses Prior to Stem Cell Transplantation
El-Serafi I; Abedi-Valugerdi M; Potacova Z; Afsharian P; Mattsson J; Moshfegh A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2013;48(6):843-848
Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion
Al Hashmi S; Sadeghi B; Hassan Z; Abedi-Valugerdi M; Lindskog M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2013;48(2):284-293
Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?
Sadeghi B; Al-Chaqmaqchi H; Al-Hashmi S; Brodin D; Hassan Z; Abedi-Valugerdi M; Moshfegh A; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2013;913:98-105
Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine
El-Serafi I; Terelius Y; Twelkmeyer B; Hagbjork A-L; Hassan Z; Hassan M
Article: PLOS ONE. 2012;7(1):e30897
Busulphan-Cyclophosphamide Cause Endothelial Injury, Remodeling of Resistance Arteries and Enhanced Expression of Endothelial Nitric Oxide Synthase
Al-Hashmi S; Boels PJM; Zadjali F; Sadeghi B; Sallstrom J; Hultenby K; Hassan Z; Arner A; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697
Improved Survival after Allogeneic Hematopoietic Stem Cell Transplantation in Recent Years. A Single-Center Study
Remberger M; Ackefors M; Berglund S; Blennow O; Dahllof G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hagglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikstrom A-C; Winiarski J; Ringden O
Article: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY. 2011;4(6):596-605
Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen
Al-Hashmi S; Hassan Z; Sadeghi B; Rozell B; Hassan M
Article: SULTAN QABOOS UNIVERSITY MEDICAL JOURNAL. 2011;11(2):165-178
The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine.
Hassan M; Sallam H; Hassan Z
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(4):1143-1153
N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro
Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Article: TRANSPLANTATION. 2010;90(9):1022-1029
Granulocyte Colony-Stimulating Factor Induced Acute and Chronic Graft-Versus-Host Disease
Ringden O; Hassan Z; Karlsson H; Olsson R; Omazic B; Mattsson J; Remberger M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2010;84(4):323-331
GVHD prophylaxis using low-dose cyclosporine improves survival in leukaemic recipients of HLA-identical sibling transplants
Olsson R; Remberger M; Hassan Z; Omazic B; Mattsson J; Ringden O
Article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2010;2010:142943
Expansion and Activation Kinetics of Immune Cells during Early Phase of GVHD in Mouse Model Based on Chemotherapy Conditioning
Sadeghi B; Al-Hashmi S; Hassan Z; Rozell B; Concha H; Lundmark C; Gronvik K-O; Abedi-Valugerdi M; Hassan M
Article: HLA. 2008;72(6):549-558
Outcome of haematopoietic stem cell transplantation in patients transplanted with matched unrelated donors vs allele-mismatched donors: a single centre study
Hauzenberger D; Schaffer M; Ringden O; Hassan Z; Omazic B; Mattsson J; Wikstrom A-C; Remberger M
Article: BONE MARROW TRANSPLANTATION. 2008;42(12):807-818
GVHD after chemotherapy conditioning in allogeneic transplanted mice
Sadeghi B; Aghdami N; Hassan Z; Forouzanfar M; Rozell B; Abedi-Valugerdi M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2008;41(10):895-904
The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model
Sadeghi B; Jansson M; Hassan Z; Mints M; Hagglund H; Abedi-Valugerdi M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2008;41(9):785-790
A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation
Barkholt L; Remberger M; Hassan Z; Fransson K; Omazic B; Svahn B-M; Karlsson H; Brune M; Hassan M; Mattsson J; Ringden O
Article: JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. 2008;31(5):683-694
Rapid and sensitive method for determination of cyclophosphamide in patients plasma samples utilizing microextraction by packed sorbent online with liquid chromatography-tandem mass spectrometry (MEPS-LC-MS/MS)
Said R; Hassan Z; Hassan M; Abdel-Rehim M
Article: BONE MARROW TRANSPLANTATION. 2008;41(4):399-405
Risk factors for acute graft-versus-host disease grades II-IV after reduced intensity conditioning allogeneic stem cell transplantation with unrelated donors -: a single centre study
Remberger M; Mattsson J; Hassan Z; Karlsson N; LeBlanc K; Omazic B; Okas M; Sairafi D; Ringden O
Article: JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. 2007;30(20):3029-3041
Simultaneous determination of busulphan in plasma samples by liquid chromatography-electrospray ionization mass spectrometry utilizing microextraction in packed syringe (MEPS) as on-line sample preparation method
Abdel-Rehim M; Hassan Z; Skansem P; Hassan M
Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 2007;60(6):841-849
Effect of the Cdk-inhibitor roscovitine on mouse hematopoietic progenitors in vivo and in vitro
Song H; Vita M; Sallam H; Tehranchi R; Nilsson C; Siden A; Hassan Z
Article: CLINICAL TRANSPLANTATION. 2007;21(5):659-667
Hemorrhagic cystitis:: a retrospective single-center survey
Hassan Z; Remberger M; Svenberg P; Elbander M; Omazic B; Mattsson J; Conrad R; Svahn B-M; Ahlgren A; Sairafi D; Aschan J; Le Blanc K; Barkholt L; Ringden O
Article: CLINICAL CANCER RESEARCH. 2007;13(14):4218-4224
The effect of repeated administration of cyclophosphamide on cytochrome P4502B in rats
Afsharian P; Zuzana YT; Hassan Z; Nilsson C; Lundgren S; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2007;39(7):383-388
Fludarabine-based disease-specific conditioning or conventional myeloablative conditioning in hematopoietic stem cell transplantation for treatment of non-malignant diseases
Ringden O; Remberger M; Svenberg P; Svahn B-M; Dahllof G; Gustafsson B; Hassan Z; Omazic B; Uzunel M; Aschan J; Barkholt L; Winiarski J; Ljungman P; Mattsson J
Article: TRANSPLANTATION. 2006;82(7):913-919
Unrelated versus related allogeneic stem cell transplantation after reduced intensity conditioning
Uzunel M; Remberger M; Sairafi D; Hassan Z; Mattsson J; Omazic B; Barkholt L; Ringden O
Article: TRANSPLANTATION. 2006;81(10):1390-1397
Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
Ringden O; Uzunel M; Rasmusson I; Remberger M; Sundberg B; Lonnies H; Marschall H-U; Dlugosz A; Szakos A; Hassan Z; Omazic B; Aschan J; Barkholt L; Le Blanc K
Article: TRANSPLANTATION. 2006;81(5):718-725
Allogeneic hematopoietic stem cell transplantation for inherited disorders:: Experience in a single center
Ringdén O; Remberger M; Svahn BM; Barkholt L; Mattsson J; Aschan J; Le Blanc K; Gustafsson B; Hassan Z; Omazic B; Svenberg P; Solders G; von Döbeln U; Winiarski J; Ljungman P; Malm G
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):115-121
Myeloablative and immunosuppressive properties of treosulfan in mice
Sjöö F; Hassan Z; Abedi-Valugerdi M; Griskevicius L; Nilsson C; Remberger M; Aschan J; Concha H; Gaughan U; Hassan M
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2006;27(1):54-61
Pharmacogenetics of cyclophosphamide in patients with hematological malignancies
Xie HJ; Griskevicius L; Ståhle L; Hassan Z; Yasar Ü; Rane A; Broberg U; Kimby E; Hassan M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(3):206-211
The effect of ciprofloxacin on cyclophosphamide pharmacokinetics in patients with non-Hodgkin lymphoma
Afsharian P; Möllgård L; Hassan Z; Xie HJ; Kimby E; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;821(1):75-80
Stability, pKa and plasma protein binding of roscovitine
Vita M; Abdel-Rehim M; Nilsson C; Hassan Z; Skansen P; Wan H; Meurling L; Hassan M
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2005;25(1):91-103
Tissue distribution, pharmacokinetics and identification of roscovitine metabolites in rat
Vita M; Abdel-Rehim M; Olofsson S; Hassan Z; Meurling L; Sidén Å; Sidén M; Pettersson T; Hassan M
Article: ANALYTICA CHIMICA ACTA. 2005;539(1-2):35-39
Microextraction in packed syringe/liquid chromatography/electrospray tandem mass spectrometry for quantification of olomoucine in human plasma samples
Abdel-Rehim M; Skansen P; Vita M; Hassan Z; Blomberg L; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(3):380-387
Effect of altering administration order of busulphan and cyclophosphamide on the myeloablative and immunosuppressive properties of the conditioning regimen in mice
Nilsson C; Forsman J; Hassan Z; Abedi-Valugerdi M; O'Connor C; Concha H; Jansson M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(4):349-354
N-acetyl-L-cysteine does not affect the pharmacokinetics or myelosuppressive effect of busulfan during conditioning prior to allogeneic stem cell transplantation
Sjöö F; Aschan J; Barkholt L; Hassan Z; Ringdén O; Hassan M
Article: THERAPEUTIC DRUG MONITORING. 2003;25(3):400-406
On-line derivatization utilizing solid-phase microextraction (SPME) for determination of busulphan in plasma using gas chromatography-mass spectrometry (GC-MS)
Abdel-Rehim M; Hassan Z; Blomberg L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2002;30(12):833-841
A phase II trial of liposomal busulphan as an intravenous myeloablative agent prior to stem cell transplantation:: 500 mg/m² as a optimal total dose for conditioning
Hassan M; Nilsson C; Hassan Z; Gungor T; Aschan J; Winiarski J; Hentschke P; Ringdén O; Eber S; Seger R; Ljungman P
Article: BONE MARROW TRANSPLANTATION. 2002;30(3):141-147
The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo
Hassan Z; Hellström-Lindberg E; Alsadi S; Edgren M; Hägglund H; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2001;28(7):657-664
Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients
Sandström M; Karlsson MO; Ljungman P; Hassan Z; Jonsson EN; Nilsson C; Ringden O; Öberg G; Bekassy A; Hassan M
Article: LEUKEMIA. 2001;15(8):1240-1247
The pharmacodynamic effect of busulfan in the P39 myeloid cell line in vitro
Hassan Z; Hassan M; Hellström-Lindberg E
Article: BONE MARROW TRANSPLANTATION. 2001;27(5):479-485
Pharmacokinetics of liposomal busulphan in man
Hassan Z; Ljungman P; Ringdén O; Winiarski J; Nilsson C; Aschan J; Whitley HR; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2000;25(9):915-924
The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite:: time interval influence on therapeutic efficacy and therapy-related toxicity
Hassan M; Ljungman P; Ringdén O; Hassan Z; Öberg G; Nilsson C; Békassy A; Bielenstein M; Abdel-Rehim M; Georén S; Astner L
Article: EXPERIMENTAL HEMATOLOGY. 1999;27(8):1322-1329
Two pathways of apoptosis induced with all-trans retinoic acid and etoposide in the myeloid cell line P39
Hassan Z; Fadeel B; Zhivotovsky B; Hellström-Lindberg E
Article: LEUKEMIA. 1999;13(5):719-728
Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells
Fadeel B; Hassan Z; Hellström-Lindberg E; Henter JI; Orrenius S; Zhivotovsky B
Article: BONE MARROW TRANSPLANTATION. 1998;22(9):913-918
Liposomal busulphan: bioavailability and effect on bone marrow in mice
Hassan Z; Nilsson C; Hassan M
Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 1998;42(6):471-478
Pharmacokinetics and distribution of liposomal busulfan in the rat:: a new formulation for intravenous administration
Hassan M; Hassan Z; Nilsson C; Rehim MA; Kumlien S; Elfsson B; Kållberg N
Article: BONE MARROW TRANSPLANTATION. 1996;18(5):843-850
Busulphan kinetics and limited sampling model in children with leukemia and inherited disorders
Hassan M; Fasth A; Gerritsen B; Haraldsson A; Syruckova Z; vandenBerg H; Sandstrom M; Karlsson M; Kumlien S; Vossen J
Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 1996;13(2):143-150
Infection-associated hemophagocytic syndrome complicated by infectious lymphoproliferation: A case report
Syruckova Z; Stary J; Sedlacek P; Smisek P; Vavrinec J; Komrska V; Roubalova K; Vandasova J; Sintakova B; Houskova J; Hassan M
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All other publications

Review: PEDIATRIC TRANSPLANTATION. 2011;15(4):348-361
Management of refractory hemorrhagic cystitis following hematopoietic stem cell transplantation in children.
Hassan Z
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(2):S345
DYNAMICS OF DONOR T CELL ACTIVATION DURING EARLY PHASE OF GRAFT VERSUS HOST DISEASE (GVHD): DONOR ANTIGEN PRESENTING CELLS CAN ACTIVATE ALLOGENEIC T CELLS
Sadeghi B; Al-Hashmi S; Hassan Z; Hassan M
Editorial comment: PEDIATRIC TRANSPLANTATION. 2010;14(6):683-687
Optimal approach to prevent veno-occlusive disease following hematopoietic stem cell transplantation in children.
Hassan Z
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):59
GVHD PROPHYLAXIS USING LOW-DOSE CYCLOSPORINE IS SAFE AND REDUCES THE RISK OF RELAPSE AND DEATH IN LEUKEMIC RECIPIENTS OF HLA-IDENTICAL SIBLING TRANSPLANTS
Olsson R; Remberger M; Mattsson J; Hassan Z; Ringden O
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):127
N-ACETYL-L-CYSTEINE PROMOTES T CELL MEDIATED IMMUNITY IN ALLOGENEIC SETTINGS IN VIVO AND IN VITRO
Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Meeting abstract: BLOOD. 2006;108(11):97A
Effect of busulphan dose adjustment on regimen-related toxicity.
Hassan Z; Remberger M; Ringden O; Oberg G; Bekassy AN; Hassan M
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2006;12(2):2
Mesenchymal stem cells for treatment of severe acute graft-versus-host disease
Ringden O; Uzunel M; Rasmusson I; Remberger ME; Sundberg B; Lonnies H; Marschall HU; Dlugosz A; Szakos A; Hassan Z; Omazic B; Aschan J; Barkholt L; Le Blanc K
Thesis / dissertation: 2001
Studies on mechanisms of busulphan cytotoxicity and pharmacokinetics : with special reference to liposomal busulphan
Hassan, Zuzana

Employments

Affiliated to Teaching/Tutoring, Department of Laboratory Medicine, Karolinska Institutet, 2022-2025

Degrees and Education

Docent, Karolinska institutet, 2009
Doctor Of Philosophy, Department of Medicine, Huddinge, Karolinska Institutet, 2001

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