Zuheng Ma

Publications
CV
Public outreach and news

Articles

Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;145:112462
Methyl ferulic acid ameliorates alcohol-induced hepatic insulin resistance via miR-378b-mediated activation of PI3K-AKT pathway
Zhang Y; Lu J; Zhong Y-J; Yang C-F; Chen L; Wu D; Song M-W; Shi L; Ma Z-H; Li L; Li Y-W
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:717
miR-378b Regulates Insulin Sensitivity by Targeting Insulin Receptor and p110α in Alcohol-Induced Hepatic Steatosis
Li Y-Y; Zhong Y-J; Cheng Q; Wang Y-Z; Fan Y-Y; Yang C-F; Ma Z; Li Y-W; Li L
Article: DIABETES, OBESITY AND METABOLISM. 2019;21(10):2219-2227
Investigating optimal β-cell-preserving treatment in latent autoimmune diabetes in adults: Results from a 21-month randomized trial
Hals IK; Fleiner HF; Reimers N; Astor MC; Filipsson K; Ma Z; Grill V; Bjorklund A
Article: JOURNAL OF MOLECULAR ENDOCRINOLOGY. 2019;62(4):159-168
Increased uptake of oxLDL does not exert lipotoxic effects in insulin-secreting cells
Ma Z; Ketelhuth DFJ; Wirstrom T; Ohki T; Forteza MJ; Wang H; Grill V; Wollheim CB; Bjorklund A
Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2018;53(1):225-236
Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway
Li L; Zhong Y; Ma Z; Yang C; Wei H; Chen L; Li C; Wu D; Rong MZ; Li Y
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2018;41(4):2306-2316
NOX4/ROS mediate ethanol-induced apoptosis via MAPK signal pathway in L-02 cells
Yang C-F; Zhong Y-J; Ma Z; Li L; Shi L; Chen L; Li C; Wu D; Chen Q; Li Y-W
Article: EXPERIMENTAL AND THERAPEUTIC MEDICINE. 2018;15(3):2228-2238
Hepatoprotective effect of methyl ferulic acid against carbon tetrachloride-induced acute liver injury in rats
Yang C; Li L; Ma Z; Zhong Y; Pang W; Xiong M; Fang S; Li Y
Article: PHYSIOLOGICAL REPORTS. 2017;5(19):e13447
Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates.
Hals I; Ohki T; Singh R; Ma Z; Björklund A; Balasuriya C; Scholz H; Grill V
Article: JOURNAL OF DIABETES RESEARCH. 2017;2017:5131785-5
A TRPM4 Inhibitor 9-Phenanthrol Inhibits Glucose- and Glucagon-Like Peptide 1-Induced Insulin Secretion from Rat Islets of Langerhans
Ma Z; Bjorklund A; Islam MS
Article: ISLETS. 2016;8(6):165-176
Culture at low glucose up-regulates mitochondrial function in pancreatic cells with accompanying effects on viability
Hals IK; Singh R; Ma Z; Scholz H; Bjoerklund A; Grill V
Article: HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION. 2016;26(1):67-76
Suppressor of cytokine signaling 2 (SOCS2) deletion protects against multiple low dose streptozotocin-induced type 1 diabetes in adult male mice.
Alkharusi A; Mirecki-Garrido M; Ma Z; Zadjali F; Flores-Morales A; Nyström T; Castrillo A; Bjorklund A; Norstedt G; Fernandez-Pérez L
Article: DIABETES. 2015;64(10):3425-3438
Toll-Like Receptor 3 Influences Glucose Homeostasis and β-Cell Insulin Secretion
Strodthoff D; Ma Z; Wirstrom T; Strawbridge RJ; Ketelhuth DFJ; Engel D; Clarke R; Falkmer S; Hamsten A; Hansson GK; Bjorklund A; Lundberg AM
Article: PANCREAS. 2015;44(5):773-777
Calcium Signaling in a Genetically Engineered Human Pancreatic β-Cell Line
Krishnan K; Ma Z; Bjoerklund A; Islam MS
Article: PLOS ONE. 2015;10(9):e0138558
Mitochondrial Respiration in Insulin-Producing β-Cells: General Characteristics and Adaptive Effects of Hypoxia
Hals IK; Bruerberg SG; Ma Z; Scholz H; Bjorklund A; Grill V
Article: PANCREAS. 2014;43(4):597-604
Role of Transient Receptor Potential Melastatin-like Subtype 5 Channel in Insulin Secretion From Rat β-Cells
Krishnan K; Ma Z; Bjorklund A; Islam MS
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;443(1):223-228
Hyperoxia inhibits glucose-induced insulin secretion and mitochondrial metabolism in rat pancreatic islets
Ma Z; Moruzzi N; Catrina S-B; Grill V; Bjorklund A
Article: PLOS ONE. 2013;8(7):e67498
Preconditioning with Associated Blocking of Ca²⁺ Inflow Alleviates Hypoxia-Induced Damage to Pancreatic β-Cells
Ma Z; Moruzzi N; Catrina S-B; Hals I; Oberholzer J; Grill V; Bjorklund A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2012;423(2):259-264
Marked over expression of uncoupling protein-2 in beta cells exerts minor effects on mitochondrial metabolism
Hals IK; Ogata H; Pettersen E; Ma Z; Bjorklund A; Skorpen F; Egeberg KW; Grill V
Article: CELL DEATH AND DISEASE. 2012;3(6):e322
Acute hypoxia induces apoptosis of pancreatic β-cell by activation of the unfolded protein response and upregulation of CHOP
Zheng X; Zheng X; Wang X; Ma Z; Sunkari VG; Botusan I; Takeda T; Bjorklund A; Inoue M; Catrina S-B; Brismar K; Poellinger L; Pereira TS
Article: ISLETS. 2012;4(3):233-242
Diabetes reduces β-cell mitochondria and induces distinct morphological abnormalities, which are reproducible by high glucose in vitro with attendant dysfunction
Ma Z; Wirstrom T; Borg LAH; Larsson-Nyren G; Hals I; Hansen JB; Grill V; Bjorklund A
Article: PLOS ONE. 2011;6(4):e18213
Evidence for Presence and Functional Effects of Kv1.1 Channels in β-Cells: General Survey and Results from mceph/mceph Mice
Ma Z; Lavebratt C; Almgren M; Portwood N; Forsberg LE; Branstrom R; Berglund E; Falkmer S; Sundler F; Wierup N; Bjorklund A
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2010;1801(2):191-197
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation
Wallin T; Ma Z; Ogata H; Jorgensen IH; Iezzi M; Wang H; Wollheim CB; Bjorklund A
Article: DIABETES. 2007;56(4):1095-1106
Effects of diazoxide on gene expression in rat pancreatic islets are largely linked to elevated glucose and potentially serve to enhance β-cell sensitivity
Ma Z; Portwood N; Brodin D; Grill V; Bjorklund A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;329(3):1118-1126
Evidence that insulin secretion influences SNAP-25 through proteasomal activation.
Ma Z; Portwood N; Foss A; Grill V; Björklund A
Article: AMERICAN JOURNAL OF PHYSIOLOGY - ENDOCRINOLOGY AND METABOLISM. 2004;287(6):E1202-E1208
Short-term intermittent exposure to diazoxide improves functional performance of β-cells in a high-glucose environment
Yoshikawa H; Ma ZH; Björklund A; Grill V
Show more

All other publications

Corrigendum: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2013;1831(2):428
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation (vol 1801, pg 191, 2010)
Wallin T; Ma Z; Ogata H; Jorgensen IH; Iezzi M; Wang H; Wollheim CB; Bjorklund A
Corrigendum: BIOCHIMICA ET BIOPHYSICA ACTA - MOLECULAR AND CELL BIOLOGY OF LIPIDS. 2011;1811(1):57
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation (vol 1801, pg 191, 2010)
Wallin T; Ma Z; Ogata H; Jorgensen IH; Iezzi M; Wang H; Wollheim CB; Bjorklund A
Thesis / dissertation: 2006
Aspects on the modulation of potassium channels in insulin-producing beta-cells
Ma, Zuheng

Employments

Research Specialist, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2022-2025

Degrees and Education

Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2006

Articles

All other publications

Employments

Degrees and Education

News from KI

Events from KI