Zhongwei Xu

About me
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About me

I got my MD at Sichuan University and PhD at Karolinska Institutet. My current research is to develop recombinant monoclonal antibodies to treat rheumatoid arthritis. After work, I'm into mushroom hunting, cooking, guitar, FPS games, and stand-up comedy.

Articles

Journal article: GENES AND IMMUNITY. 2024;:1-4
The need for Cre-loci controls in conditional mouse experiments: Mrp8-cre transgene predisposes mice to antibody-induced arthritis
Xu Z; Romero-Castillo L; Moreno-Giro A; Pandey RK; Holmdahl R
Article: ADVANCED SCIENCE. 2024;11(23):e2401513
Human MHC Class II and Invariant Chain Knock-in Mice Mimic Rheumatoid Arthritis with Allele Restriction in Immune Response and Arthritis Association
Romero-Castillo L; Li T; Do N-N; Sareila O; Xu B; Hennings V; Xu Z; Svensson C; Oliveira-Coelho A; Sener Z; Urbonaviciute V; Ekwall O; Burkhardt H; Holmdahl R
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2024;54(4):e2350659
Fcgr2b and Fcgr3 are the major genetic factors for cartilage antibody-induced arthritis, overriding the effect of Hc encoding complement C5
Xu Z; Moreno-Giro A; Zhao D; Kramer A; Pandey RK; Xu B; Lundstrom SL; Holmdahl R
Article: JOURNAL OF EXPERIMENTAL MEDICINE (JEM). 2023;220(11):e20230101
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice.
Aoun M; Coelho A; Krämer A; Saxena A; Sabatier P; Beusch CM; Lönnblom E; Geng M; Do N-N; Xu Z; Zhang J; He Y; Romero Castillo L; Abolhassani H; Xu B; Viljanen J; Rorbach J; Fernandez Lahore G; Gjertsson I; Kastbom A; Sjöwall C; Kihlberg J; Zubarev RA; Burkhardt H; Holmdahl R
Article: NATURE COMMUNICATIONS. 2023;14(1):5949
A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils
Xu Z; Xu B; Lundstrom SL; Moreno-Giro A; Zhao D; Martin M; Lonnblom E; Li Q; Kramer A; Ge C; Cheng L; Liang B; Tong D; Stawikowska R; Blom AM; Fields GB; Zubarev RA; Holmdahl R
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2022;79(9):482
Two major genes associated with autoimmune arthritis, Ncf1 and Fcgr2b, additively protect mice by strengthening T cell tolerance
Li Q; Zhong J; Luo H; Urbonaviciute V; Xu Z; He C; Holmdahl R
Article: JOURNAL OF CROHN'S AND COLITIS. 2022;16(4):633-642
Depression and Inflammatory Bowel Disease: A Bidirectional Two-sample Mendelian Randomization Study
Luo J; Xu Z; Noordam R; van Heemst D; Li-Gao R
Article: JOURNAL OF ANATOMY. 2018;233(2):213-221
The prevalence and morphological characteristics of the knee anterolateral ligament in a Chinese population
Zhang H; Qiu M; Xu Z; Wang W; Chen S; Zhang J; Zhou A; Lu K; Huo M; Jiang D
Article: AMERICAN JOURNAL OF PHYSICAL MEDICINE AND REHABILITATION. 2017;96(11):793-800
Efficacy of Platelet-Rich Plasma in Pain and Self-Report Function in Knee Osteoarthritis A Best-Evidence Synthesis
Xu Z; Luo J; Huang X; Wang B; Zhang J; Zhou A
Article: PHYSICIAN AND SPORTSMEDICINE. 2017;45(3):316-322
Preemptive analgesia by using celecoxib combined with tramadol/APAP alleviates post-operative pain of patients undergoing total knee arthroplasty
Xu Z; Zhang H; Luo J; Zhou A; Zhang J
Journal article: METABOLOMICS. 2017;13(6):73
Serum metabolomic study for detecting biomarkers of non-traumatic osteonecrosis of the femoral head
Xu Z; Xu K; Ding S; Luo J; Chen T; Zhou A; Wen Z; Zhang J
Article: JOURNAL OF PROTEOME RESEARCH. 2017;16(4):1425-1435
Cartilaginous Metabolomic Study Reveals Potential Mechanisms of Osteophyte Formation in Osteoarthritis
Xu Z; Chen T; Luo J; Ding S; Gao S; Zhang J
Journal article: MEDICINE (UNITED KINGDOM). 2017;96(1):e5614
Efficacy of Kirschner-wires and tension band in hip arthroplasty for aged patients with unstable intertrochanteric osteoporotic fracture: A 2-to-11-year follow-up.
Zhang H; Xu Z; Zhou A; Yan W; Zhao P; Huang X; Zhang J
Journal article: ANALYTICAL AND BIOANALYTICAL CHEMISTRY. 2016;408(16):4275-4286
Metabolic analysis of osteoarthritis subchondral bone based on UPLC/Q-TOF-MS
Yang G; Zhang H; Chen T; Zhu W; Ding S; Xu K; Xu Z; Guo Y; Zhang J
Journal article: METABOLOMICS. 2016;12(3):48
Metabolomic study of the bone trabecula of osteonecrosis femoral head patients based on UPLC-MS/MS
Zhu W; Chen T; Ding S; Yang G; Xu Z; Xu K; Zhang S; Ma T; Zhang J

All other publications

Review: ANNALS OF THE RHEUMATIC DISEASES. 2024;83(5):550-555
Shift in perspective: autoimmunity protecting against rheumatoid arthritis
He Y; Aoun M; Xu Z; Holmdahl R
Thesis / dissertation: 2023
Beyond conventional care : developing novel therapeutic approaches to combat arthritis
Xu, Zhongwei

Employments

Postdoctoral Researcher, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2024-2026
Phd Student, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2023-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 2023
MD, Clinical Medicine, West China Medical Center, Sichuan University, 2014

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