Yizhou Hu
Postdoctoral Researcher
E-mail: yizhou.hu@ki.se
Visiting address: Solnavägen 9, 6C, 17177 Stockholm
Postal address: C2 Medicinsk biokemi och biofysik, C2 Molekylär neurobiologi Ernfors, 171 77 Stockholm
About me
- Molecular system biology, work on molecular biochemistry and translational
medicine since 2005, coding since 2008.
* Ph.D., Pathology (Oncology and Molecular Cell Biology), Translational
Cancer Biology Program, Faculty of Medicine, University of Helsinki,
Finland
* M.Sc., Genetics (Human Genetics and Bioinformatics), Faculty of Biological
and Environmental Sciences, University of Helsinki, Finland
* B.Sc., Biotechnology (Medical Biotechnology), Life Science College of
Soochow University, Suzhou, China
Research
- Nervous system tumor, single-cell/spatial technology, developmental
neurobiology, and deep learning.
*Recent Publications: *
* Neogenin suppresses tumor progression and metastasis via inhibiting
Merlin/YAP signaling [1], Cell Death Discov., 2023
* Neural network learning defines glioblastoma features to be of neural
crest perivascular or radial glia lineages [2], Sci Adv., 2022
* Single cell transcriptional zonation of human psoriasis skin identifies an
alternative immunoregulatory axis conducted by skin resident cells
[3], Cell Death Dis., 2021
*Software:*
1) SWAPLINE, Single-cell Weighted Assignment and Projection on developmental
LINEages [4]
2) scCAMEL, learning-based single-cell analysis toolkits,
website: https://sccamel.readthedocs.io/ [5]
*Dataset visualization:*
1. Single cell transcriptional zonation of human psoriasis skin identifies
an alternative immunoregulatory axis conducted by skin resident cells, Cell
Death Dis., 2021
Website: https://yz-studio.shinyapps.io/shinyapph5ad/ [6]
[1] https://pubmed.ncbi.nlm.nih.gov/36746934/
[2] https://pubmed.ncbi.nlm.nih.gov/35675414/
[3] https://pubmed.ncbi.nlm.nih.gov/33958582/
[4] https://github.com/ernforslab/Hu-et-al._GBMlineage2022
[5] https://sccamel.readthedocs.io
[6] https://yz-studio.shinyapps.io/shinyapph5ad/
Articles
- Article: BMC CANCER. 2024;24(1):89
- Article: NATURE METABOLISM. 2023;5(7):1188-1203
- Article: CELL DEATH DISCOVERY. 2023;9(1):47
- Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1265517
- Article: SCIENCE ADVANCES. 2022;8(23):eabm6340
- Article: STEM CELL REPORTS. 2022;17(5):1089-1104
- Article: CELL DEATH & DISEASE. 2021;12(5):450
- Article: NATURE COMMUNICATIONS. 2021;12(1):2141
- Article: NATURE COMMUNICATIONS. 2021;12(1):1510
- Article: BMC CANCER. 2018;18(1):1215