Vijay Joshua

About me
Publications
CV
Public outreach and news

About me

I am a Postdoctoral Researcher at the Rheumatology Unit.

Research

I have been working on studies that try to understand the role of the lungs
in the initiation of Rheumatoid Arthritis (RA). More specifically, I have
been studying the immunogenetics and Citrulline reactivity of the lung B
cells in lungs of risk RA and early untreated RA.

Teaching

Course Organiser
Cytokines in Inflammation (PhD Course - 3 ECTS - 2 Weeks ) - 2021, 2022.2024
Teaching
Cytokines in Inflammation (PhD Course - 3 ECTS - 2 Weeks ) - 2019, 2021, 2022, 2024

Articles

Article: RHEUMATOLOGY. 2024;63(11):3164-3171
Identification of early risk factors for anti-citrullinated-protein-antibody positive rheumatoid arthritis-a prospective cohort study
Circiumaru A; Kisten Y; Hansson M; Mathsson-Alm L; Joshua V; Waehaemaa H; Loberg Haarhaus M; Lindqvist J; Padyukov L; Catrina S-B; Fei G; Vivar N; Rezaei H; af Klint E; Antovic A; Rethi B; Catrina AI; Hensvold A
Article: RHEUMATOLOGY. 2024;63(11):3106-3114
Identification of circulating autoantibodies to non-modified proteins associated with ACPA status in early rheumatoid arthritis
Lourido L; Joshua V; Hansson M; Sjoberg R; Pin E; Ruiz-Romero C; Nilsson P; Alfredsson L; Klareskog L; Blanco FJ
Article: SCIENTIFIC REPORTS. 2024;14(1):15511
Evidence of membranolytic targeting and intracellular citrullination in neutrophils isolated from patients with rheumatoid arthritis
Moadab F; Wang X; Le E; Gazitt T; Najjar R; Nelson JL; Joshua V; Malmstrom V; Elkon K; Groenwall C; Mustelin T
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2023;299(11):105320
Autoreactive B cells against malondialdehyde-induced protein cross-links are present in the joint, lung, and bone marrow of rheumatoid arthritis patients
Sahlstrom P; Joshua V; Valkovskaia V; Biese C; Stalesen R; Israelsson L; Vegvari A; Scheel-Toellner D; Klareskog L; Hansson M; Hensvold A; Malmstrom V; Gronwall C
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(11):1910-1922
Rheumatoid Arthritis-Specific Autoimmunity in the Lung Before and at the Onset of Disease
Joshua V; Loberg Haarhaus M; Hensvold A; Wahamaa H; Gerstner C; Hansson M; Israelsson L; Stalesen R; Skoeld M; Grunewald J; Klareskog L; Groenwall C; Rethi B; Catrina A; Malmstrom V
Article: RESPIROLOGY. 2023;28(10):925-933
Presence of anti-modified protein antibodies in idiopathic pulmonary fibrosis
Kalafatis D; Joshua V; Hansson M; Mathsson-Alm L; Hensvold A; Skold M
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):239
The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual "window of treatment success" in RA patients
Marklein B; Jenning M; Konthur Z; Haupl T; Welzel F; Nonhoff U; Krobitsch S; Mulder DM; Koenders MI; Joshua V; Cope AP; Shlomchik MJ; Anders H-J; Burmester GR; Hensvold A; Catrina AI; Ronnelid J; Steiner G; Skriner K
Article: RMD OPEN. 2021;7(2):e001662
Tocilizumab decreases T cells but not macrophages in the synovium of patients with rheumatoid arthritis while it increases the levels of serum interleukin-6 and RANKL
Chatzidionysiou K; Circiumaru A; Rethi B; Joshua V; Engstrom M; Hensvold A; af Klint E; Catrina A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:627986
A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis
Gronwall C; Liljefors L; Bang H; Hensvold AH; Hansson M; Mathsson-Alm L; Israelsson L; Joshua V; Svard A; Stalesen R; Titcombe PJ; Steen J; Piccoli L; Sherina N; Clavel C; Svenungsson E; Gunnarsson I; Saevarsdottir S; Kastbom A; Serre G; Alfredsson L; Malmstrom V; Ronnelid J; Catrina AI; Lundberg K; Klareskog L
Article: BIO-PROTOCOL. 2021;11(6):e3957
An Image-based Dynamic High-throughput Analysis of Adherent Cell Migration
Sun M; Rethi B; Krishnamurthy A; Joshua V; Wahamaa H; Catrina S-B; Catrina A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2020;79(9):1194-1202
Bacterial citrullinated epitopes generated by Porphyromonas gingivalis infection-a missing link for ACPA production
Jenning M; Marklein B; Ytterberg J; Zubarev RA; Joshua V; van Schaardenburg D; van de Stadt L; Catrina AI; Nonhoff U; Haupl T; Konthur Z; Burmester GR; Skriner K
Article: RMD OPEN. 2020;6(2):e001278
Association between number and type of different ACPA fine specificities with lung abnormalities in early, untreated rheumatoid arthritis
Joshua V; Hensvold AH; Reynisdottir G; Hansson M; Cornillet M; Nogueira L; Serre G; Nyren S; Karimi R; Eklund A; Skold M; Grunewald J; Chatzidionysiou K; Catrina A
Article: RHEUMATOLOGY. 2020;59(4):852-859
Secretory anti-citrullinated protein antibodies in serum associate with lung involvement in early rheumatoid arthritis
Ljungberg KR; Joshua V; Skogh T; Eklund A; Skold CM; Karimi R; Nyren S; Svard A; Catrina AI; Kastbom A
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631
Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts
Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Gronwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wahamaa H; Catrina AI
Article: JOURNAL OF IMMUNOLOGY. 2019;202(11):3143-3150
Citrullination Controls Dendritic Cell Transdifferentiation into Osteoclasts
Krishnamurthy A; Ytterberg AJ; Sun M; Sakuraba K; Steen J; Joshua V; Tarasova NK; Malmstrom V; Wahamaa H; Rethi B; Catrina AI
Article: BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY. 2017;31(1):31-41
Role of the lung in individuals at risk of rheumatoid arthritis
Joshua V; Chatzidionisyou K; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2016;18(1):284
Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells
Joshua V; Schobers L; Titcombe PJ; Israelsson L; Ronnelid J; Hansson M; Catrina AI; Pruijn GJM; Malmstrom V
Article: MICROBIOME. 2016;4(1):60
The lung microbiota in early rheumatoid arthritis and autoimmunity
Scher JU; Joshua V; Artacho A; Abdollahi-Roodsaz S; Ockinger J; Kullberg S; Skold M; Eklund A; Grunewald J; Clemente JC; Ubeda C; Segal LN; Catrina AI
Article: SCIENTIFIC REPORTS. 2016;6:33811
expression profiling of receptive endometrium reveals progesterone regulated ENPP3 is differentially expressed and secreted in glycosylated form
Boggavarapu NR; Lalitkumar S; Joshua V; Kasvandik S; Salumets A; Lalitkumar PG; Gemzell-Danielsson K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(9):1722-1727
Signs of immune activation and local inflammation are present in the bronchial tissue of patients with untreated early rheumatoid arthritis
Reynisdottir G; Olsen H; Joshua V; Engstrom M; Forsslund H; Karimi R; Skold CM; Nyren S; Eklund A; Grunewald J; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss
Krishnamurthy A; Joshua V; Hensvold AH; Jin T; Sun M; Vivar N; Ytterberg AJ; Engstrom M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jimenez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmstrom V; Klareskog L; Wahamaa H; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):239
Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate
Hensvold AH; Joshua V; Li W; Larkin M; Qureshi F; Israelsson L; Padyukov L; Lundberg K; Defranoux N; Saevarsdottir S; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(9):1772-1777
Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation
Ytterberg AJ; Joshua V; Reynisdottir G; Tarasova NK; Rutishauser D; Ossipova E; Hensvold AH; Eklund A; Skold CM; Grunewald J; Malmstrom V; Jakobsson PJ; Ronnelid J; Padyukov L; Zubarev RA; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(2):375-380
Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins
Hensvold AH; Magnusson PKE; Joshua V; Hansson M; Israelsson L; Ferreira R; Jakobsson P-J; Holmdahl R; Hammarstrom L; Malmstrom V; Askling J; Klareskog L; Catrina AI
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(1):31-39
Structural Changes and Antibody Enrichment in the Lungs Are Early Features of Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis
Reynisdottir G; Karimi R; Joshua V; Olsen H; Hensvold AH; Harju A; Engstrom M; Grunewald J; Nyren S; Eklund A; Klareskog L; Skold CM; Catrina AI
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All other publications

Corrigendum: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):255
The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual " window of treatment success" in RA patients (vol 23, 239, 2021)
Marklein B; Jenning M; Konthur Z; Haeupl T; Welzel F; Nonhoff U; Krobitsch S; Mulder DM; Koenders MI; Joshua V; Cope AP; Shlomchik MJ; Anders H-J; Burmester GR; Hensvold A; Catrina AI; Roennelid J; Steiner G; Skriner K
Corrigendum: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(6):866
Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss (vol 75, pg 721, 2016)
Krishnamurthy A; Joshua V; Hensvold HA
Other: JOURNAL OF EXPERIMENTAL MEDICINE. 2019;216(1):245
Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition (Retraction of Vol 210, Pg 3, 2013)
Amara K; Steen J; Murray F; Morbach H; Fernandez-Rodriguez BM; Joshua V; Engstrom M; Snir O; Israelsson L; Catrina AI; Wardemann H; Corti D; Meffre E; Klareskog L; Malmstrom V
Doctoral thesis: 2017
Antibody-associated inflammation in and outside the joint in rheumatoid arthritis
Balasingh VJ
Review: IMMUNOLOGICAL REVIEWS. 2016;269(1):162-174
Mechanisms involved in triggering rheumatoid arthritis
Catrina AI; Joshua V; Klareskog L; Malmstrom V

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