Vanessa Monteil

Publications
CV
Public outreach and news

Selected publications

Article: NATURE MICROBIOLOGY. 2024;9(5):1499-1512
Crimean-Congo haemorrhagic fever virus uses LDLR to bind and enter host cells
Monteil VM; Wright SC; Dyczynski M; Kellner MJ; Appelberg S; Platzer SW; Ibrahim A; Kwon H; Pittarokoilis I; Mirandola M; Michlits G; Devignot S; Elder E; Abdurahman S; Bereczky S; Bagci B; Youhanna S; Aastrup T; Lauschke VM; Salata C; Elaldi N; Weber F; Monserrat N; Hawman DW; Feldmann H; Horn M; Penninger JM; Mirazimi A
Article: NATURE COMMUNICATIONS. 2023;14(1):6785
Identification of CCZ1 as an essential lysosomal trafficking regulator in Marburg and Ebola virus infections
Monteil V; Kwon H; John L; Salata C; Jonsson G; Vorrink SU; Appelberg S; Youhanna S; Dyczynski M; Leopoldi A; Leeb N; Volz J; Hagelkruys A; Kellner MJ; Devignot S; Michlits G; Foong-Sobis M; Weber F; Lauschke VM; Horn M; Feldmann H; Elling U; Penninger JM; Mirazimi A
Article: CELL. 2020;181(4):905-913.e7
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2
Monteil V; Kwon H; Prado P; Hagelkruys A; Wimmer RA; Stahl M; Leopoldi A; Garreta E; del Pozo CH; Prosper F; Romero JP; Wirnsberger G; Zhang H; Slutsky AS; Conder R; Montserrat N; Mirazimi A; Penninger JM

Articles

Article: VIRUSES. 2024;16(10):1539
A CRISPR-Cas13b System Degrades SARS-CoV and SARS-CoV-2 RNA In Vitro
Andersson K; Azatyan A; Ekenberg M; Gucluler G; Sardon Puig L; Puumalainen M; Pramer T; Monteil VM; Mirazimi A
Article: MICROORGANISMS. 2024;12(3):443
P53-Independent G1-Cell Cycle Arrest Increases SARS-CoV-2 RNA Replication
Husser C; Kwon H; Andersson K; Appelberg S; Montserrat N; Mirazimi A; Monteil VM
Article: NATURE COMMUNICATIONS. 2022;13(1):7926
Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level
Zhu R; Canena D; Sikora M; Klausberger M; Seferovic H; Mehdipour AR; Hain L; Laurent E; Monteil V; Wirnsberger G; Wieneke R; Tampe R; Kienzl NF; Mach L; Mirazimi A; Oh YJ; Penninger JM; Hummer G; Hinterdorfer P
Article: STAR PROTOCOLS. 2022;3(4):101872
Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cells
Garreta E; Moya-Rull D; Stanifer ML; Monteil V; Prado P; Marco A; Tarantino C; Gallo M; Jonsson G; Hagelkruys A; Mirazimi A; Boulant S; Penninger JM; Montserrat N
Article: EMBO MOLECULAR MEDICINE. 2022;14(8):e15230
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants
Monteil V; Eaton B; Postnikova E; Murphy M; Braunsfeld B; Crozier I; Kricek F; Niederhofer J; Schwarzbock A; Breid H; Devignot S; Klingstrom J; Thalin C; Kellner MJ; Christ W; Havervall S; Mereiter S; Knapp S; Jimenez AS; Bugajska-Schretter A; Dohnal A; Ruf C; Gugenberger R; Hagelkruys A; Montserrat N; Kozieradzki I; Ali OH; Stadlmann J; Holbrook MR; Schmaljohn C; Oostenbrink C; Shoemaker RH; Mirazimi A; Wirnsberger G; Penninger JM
Article: CELL METABOLISM. 2022;34(6):857-873.e9
A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
Garreta E; Prado P; Stanifer ML; Monteil V; Marco A; Ullate-Agote A; Moya-Rull D; Vilas-Zornoza A; Tarantino C; Pablo Romero J; Jonsson G; Oria R; Leopoldi A; Hagelkruys A; Gallo M; Gonzalez F; Domingo-Pedrol P; Gavalda A; Hurtado del Pozo C; Hasan Ali O; Ventura-Aguiar P; Maria Campistol J; Prosper F; Mirazimi A; Boulant S; Penninger JM; Montserrat N
Article: ELIFE. 2022;11:e76071
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target
Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci BK; Gupta S; Rodriguez JE; Svensson-Akusjarvi S; Monteil V; Vegvari A; Benfeitas R; Banerjea A; Weber F; Hewson R; Mirazimi A
Article: JOURNAL OF VIROLOGY. 2022;96(3):e0156821-e01521
Nucleoside-Modified mRNA Vaccines Protect IFNAR^-/- Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
Appelberg S; John L; Pardi N; Vegvari A; Bereczky S; Ahlen G; Monteil V; Abdurahman S; Mikaeloff F; Beattie M; Tam Y; Sallberg M; Neogi U; Weissman D; Mirazimi A
Article: ELIFE. 2021;10:e73641
Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor
Capraz T; Kienzl NF; Laurent E; Perthold JW; Foederl-Hoebenreich E; Gruenwald-Gruber C; Maresch D; Monteil V; Niederhofer J; Wirnsberger G; Mirazimi A; Zatloukal K; Mach L; Penninger JM; Oostenbrink C; Stadlmann J
Article: CELL GENOMICS. 2021;1(3):100065
Genome-wide spatial expression profiling in formalin-fixed tissues
Villacampa EG; Larsson L; Mirzazadeh R; Kvastad L; Andersson A; Mollbrink A; Kokaraki G; Monteil V; Schultz N; Appelberg KS; Montserrat N; Zhang H; Penninger JM; Miesbach W; Mirazimi A; Carlson J; Lundeberg J
Article: JOURNAL OF VIROLOGY. 2021;95(24):e0163821-10.1128/jvi.01621
Virus-Derived DNA Forms Mediate the Persistent Infection of Tick Cells by Hazara Virus and Crimean-Congo Hemorrhagic Fever Virus
Salvati MV; Salaris C; Monteil V; Del Vecchio C; Palu G; Parolin C; Calistri A; Bell-Sakyi L; Mirazimi A; Salata C
Article: EMBO JOURNAL. 2021;40(19):e108375
Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites
Hoffmann D; Mereiter S; Oh YJ; Monteil V; Elder E; Zhu R; Canena D; Hain L; Laurent E; Gruenwald-Gruber C; Klausberger M; Jonsson G; Kellner MJ; Novatchkova M; Ticevic M; Chabloz A; Wirnsberger G; Hagelkruys A; Altmann F; Mach L; Stadlmann J; Oostenbrink C; Mirazimi A; Hinterdorfer P; Penninger JM
Article: BIOTECHNOLOGY JOURNAL. 2021;16(6):e2000566
Generation of enzymatically competent SARS-CoV-2 decoy receptor ACE2-Fc in glycoengineered Nicotiana benthamiana
Castilho A; Schwestka J; Kienzl NF; Vavra U; Gruenwald-Gruber C; Izadi S; Hiremath C; Niederhoefer J; Laurent E; Monteil V; Mirazimi A; Wirnsberger G; Stadlmann J; Stoeger E; Mach L; Strasser R
Article: JOURNAL OF VIROLOGICAL METHODS. 2021;290:114075
Serological and molecular study of Crimean-Congo Hemorrhagic Fever Virus in cattle from selected districts in Uganda
Balinandi S; von Bromssen C; Tumusiime A; Kyondo J; Kwon H; Monteil VM; Mirazimi A; Lutwama J; Mugisha L; Malmberg M
Article: NATURE MICROBIOLOGY. 2021;6(2):187-195
A DNA-based vaccine protects against Crimean-Congo haemorrhagic fever virus disease in a Cynomolgus macaque model
Hawman DW; Ahlen G; Appelberg KS; Meade-White K; Hanley PW; Scott D; Monteil V; Devignot S; Okumura A; Weber F; Feldmann H; Sallberg M; Mirazimi A
Article: EMBO MOLECULAR MEDICINE. 2021;13(1):e13426
Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection
Monteil V; Dyczynski M; Lauschke VM; Kwon H; Wirnsberger G; Youhanna S; Zhang H; Slutsky AS; Hurtado del Pozo C; Horn M; Montserrat N; Penninger JM; Mirazimi A
Article: SCIENCE ADVANCES. 2021;7(1):eabe4724
JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
Stebbing J; Nievas GS; Falcone M; Youhanna S; Richardson P; Ottaviani S; Shen JX; Sommerauer C; Tiseo G; Ghiadoni L; Virdis A; Monzani F; Rizos LR; Forfori F; Avendano-Cespedes A; De Marco S; Carrozzi L; Lena F; Sanchez-Jurado PM; Lacerenza LG; Cesira N; Caldevilla-Bernardo D; Perrella A; Niccoli L; Mendez LS; Matarrese D; Goletti D; Tan Y-J; Monteil V; Dranitsaris G; Cantini F; Farcomeni A; Dutta S; Burley SK; Zhang H; Pistello M; Li W; Romero MM; Pretel FA; Simon-Talero RS; Garcia-Molina R; Kutter C; Felce JH; Nizami ZF; Miklosi AG; Penninger JM; Menichetti F; Mirazimi A; Abizanda P; Lauschke VM
Article: PLOS NEGLECTED TROPICAL DISEASES. 2020;14(11):e0008863
Hazara virus and Crimean-Congo Hemorrhagic Fever Virus show a different pattern of entry in fully-polarized Caco-2 cell line
Monteil V; Salata C; Appelberg S; Mirazimi A
Article: EMBO MOLECULAR MEDICINE. 2020;12(8):e12697
Mechanism of baricitinib supports artificial intelligence-predicted testing inCOVID-19 patients
Stebbing J; Krishnan V; de Bono S; Ottaviani S; Casalini G; Richardson PJ; Monteil V; Lauschke VM; Mirazimi A; Youhanna S; Tan Y-J; Baldanti F; Sarasini A; Terres JAR; Nickoloff BJ; Higgs RE; Rocha G; Byers NL; Schlichting DE; Nirula A; Cardoso A; Corbellino M
Article: EUROSURVEILLANCE. 2020;25(28):19-28
Monoclonal antibodies for the S2 subunit of spike of SARS-CoV-1 cross-react with the newly-emerged SARS-CoV-2
Zheng Z; Monteil VM; Maurer-Stroh S; Yew CW; Leong C; Mohd-Ismail NK; Arularasu SC; Chow VTK; Lin RTP; Mirazimi A; Hong W; Tan Y-J
Article: TICKS AND TICK-BORNE DISEASES. 2020;11(4):101417
Identification and validation of internal reference genes for real-time quantitative polymerase chain reaction-based studies in Hyalomma anatolicum ticks
Salata C; Monteil V; Leijon M; Bell-Sakyi L; Mirazimi A
Article: FRONTIERS IN MEDICINE. 2020;7:225
Development and Potential Usefulness of the COVID-19 Ag Respi-Strip Diagnostic Assay in a Pandemic Context
Mertens P; De Vos N; Martiny D; Jassoy C; Mirazimi A; Cuypers L; Van den Wijngaert S; Monteil V; Melin P; Stoffels K; Yin N; Mileto D; Delaunoy S; Magein H; Lagrou K; Bouzet J; Serrano G; Wautier M; Leclipteux T; Van Ranst M; Vandenberg O
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2018;15(12):E2775-2775
Emerging Mosquito-Borne Threats and the Response from European and Eastern Mediterranean Countries
Johnson N; de Marco MF; Giovannini A; Ippoliti C; Danzetta ML; Svartz G; Erster O; Groschup MH; Ziegler U; Mirazimi A; Monteil V; Beck C; Gonzalez G; Lecollinet S; Attoui H; Moutailler S
Article: BIOSCIENCE REPORTS. 2018;38(5):BSR20181059
Overexpression of the nucleocapsid protein of Middle East respiratory syndrome coronavirus up-regulates CXCL10
Aboagye JO; Yew CW; Ng O-W; Monteil VM; Mirazimi A; Tan Y-J
Journal article: JOURNAL OF HUMAN VIROLOGY & RETROVIROLOGY. 2016;4(2)
Circulation of Dengue Virus Type 3 Genotype III in Africa Since 2008
Maquart M
Article: BULLETIN DE LA SOCIETE DE PATHOLOGIE EXOTIQUE. 2016;109(4):272-280
[The register of activity at the Ebola treatment center in Forecariah (Guinea) from april 23 to june 5, 2015: analysis and thoughts].
Gaüzère B-A; Ouellet I; Nottebrock D; Nied J-C; Beya-Kadiebwe B; Camara AK; Camara D; Camara MLM; Camara M; Soumah A; Tounkara MK; Monteil V; Camara A; Bauffe F; Camara A; Camara IB; Sissoko D; Simon B; Jaspard M; Tran-Minh T; L'Hériteau F
Article: BULLETIN DE LA SOCIETE DE PATHOLOGIE EXOTIQUE. 2016;109(4):248-255
[Input of a laboratory in the management of patients with Ebola virus disease and in the training of health personnel: experience of the Forecariah Ebola treatment centre (Guinea) in 2015].
Gaüzère B-A; Ouellet I; Nottebrock D; Nied J-C; Beya-Kadiebwe B; Camara AK; Camara D; Camara MLM; Camara M; Soumah A; Tounkara MK; Monteil V; Camara A; Bauffe F; Camara A; Camara IB; Simon B; Jaspard M; Tran-Minh T; L'Hériteau F
Article: NATURE. 2016;530(7589):228-232
Real-time, portable genome sequencing for Ebola surveillance
Quick J; Loman NJ; Duraffour S; Simpson JT; Severi E; Cowley L; Bore JA; Koundouno R; Dudas G; Mikhail A; Ouedraogo N; Afrough B; Bah A; Baum JHJ; Becker-Ziaja B; Boettcher JP; Cabeza-Cabrerizo M; Camino-Sanchez A; Carter LL; Doerrbecker J; Enkirch T; Garcia-Dorival I; Hetzelt N; Hinzmann J; Holm T; Kafetzopoulou LE; Koropogui M; Kosgey A; Kuisma E; Logue CH; Mazzarelli A; Meisel S; Mertens M; Michel J; Ngabo D; Nitzsche K; Pallasch E; Patrono LV; Portmann J; Repits JG; Rickett NY; Sachse A; Singethan K; Vitoriano I; Emanaberhan RLY; Zekeng EG; Racine T; Bello A; Sall AA; Faye O; Faye O; Magassouba N; Williams CV; Amburgey V; Winona L; Davis E; Gerlach J; Washington F; Monteil V; Jourdain M; Bererd M; Camara A; Somlare H; Camara A; Gerard M; Bado G; Baillet B; Delaune D; Nebie KY; Diarra A; Savane Y; Pallawo RB; Gutierrez GJ; Milhano N; Roger I; Williams CJ; Yattara F; Lewandowski K; Taylor J; Rachwal P; Turner DJ; Pollakis G; Hiscox JA; Matthews DA; O'Shea MK; Johnston AM; Wilson D; Hutley E; Smit E; DiCaro A; Woelfel R; Stoecker K; Fleischmann E; Gabriel M; Weller SA; Koivogui L; Diallo B; Keita S; Rambaut A; Formenty P; Guenther S; Carroll MW
Article: ARCHIVES OF VIROLOGY. 2011;156(11):2023-2032
Phenotypic and genotypic characterization of dengue virus isolates differentiates dengue fever and dengue hemorrhagic fever from dengue shock syndrome
Tuiskunen A; Monteil V; Plumet S; Boubis L; Wahlstrom M; Duong V; Buchy P; Lundkvist A; Tolou H; Leparc-Goffart I
Article: EMERGING INFECTIOUS DISEASES. 2011;17(2):271-274
Novel HIV-1 Recombinant Forms in Antenatal Cohort, Montreal, Quebec, Canada
Quesnel-Vallieres M; Kouzayha I; Tran E; Barry I; Lasgi C; Merindol N; Monteil V; Ransy DG; Boucher M; Lapointe N; Soudeyns H
Article: JOURNAL OF GENERAL VIROLOGY. 2010;91(Pt 4):1019-1027
Self-priming of reverse transcriptase impairs strand-specific detection of dengue virus RNA
Tuiskunen A; Leparc-Goffart I; Boubis L; Monteil V; Klingstrom J; Tolou HJ; Lundkvist A; Plumet S
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All other publications

Corrigendum: NATURE COMMUNICATIONS. 2023;14(1):1142
Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level(Dec, 10.1038/s41467-022-35641-3,2022)
Zhu R; Canena D; Sikora M; Klausberger M; Seferovic H; Mehdipour AR; Hain L; Laurent E; Monteil V; Wirnsberger G; Wieneke R; Tampe R; Kienzl NF; Mach L; Mirazimi A; Oh YJ; Penninger JM; Hummer G; Hinterdorfer P
Letter: CELL. 2022;185(11):1837-1839
Evidence in favor of the essentiality of human cell membrane-bound ACE2 and against soluble ACE2 for SARS-CoV-2 infectivity
Batlle D; Monteil V; Garreta E; Hassler L; Wysocki J; Chandar V; Schwartz RE; Mirazimi A; Montserrat N; Bader M; Penninger JM
Review: PATHOGENS. 2022;11(2):271
Methods of Inactivation of Highly Pathogenic Viruses for Molecular, Serology or Vaccine Development Purposes
Elveborg S; Monteil VM; Mirazimi A
Preprint: BIORXIV. 2021
Clinical grade ACE2 effectively inhibits SARS-CoV-2 Omicron infections
Monteil V; Stephanie D; Klingström J; Thålin C; Kellner M; Christ W; Havervall S; Mereiter S; Knapp S; Montserrat N; Braunsfeld B; Kozieradzki I; Ali OH; Hagelkruys A; Stadlmann J; Oostenbrink C; Wirnsberger G; Penninger J; Mirazimi A
Preprint: BIORXIV. 2021;BIORXIV
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants.
Wirnsberger G; Monteil V; Eaton B; Postnikova E; Murphy M; Braunsfeld B; Crozier I; Kricek F; Niederhöfer J; Schwarzböck A; Breid H; Jimenez AS; Bugajska-Schretter A; Dohnal A; Ruf C; Gugenberger R; Hagelkruys A; Montserrat N; Holbrook MR; Oostenbrink C; Shoemaker RH; Mirazimi A; Penninger JM
Preprint: BIORXIV. 2021
Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor
Capraz T; Kienzl N; Laurent E; Perthold J; Föderl-Höbenreich E; Grünwald-Gruber C; Maresch D; Monteil V; Niederhöfer J; Wirnsberger G; Mirazimi A; Zatloukal K; Mach L; Penninger J; Oostenbrink C; Stadlmann J
Preprint: BIORXIV. 2021
A diabetic milieu increases cellular susceptibility to SARS-CoV-2 infections in engineered human kidney organoids and diabetic patients
Garreta E; Prado P; Stanifer M; Monteil V; del Pozo CH; Ullate-Agote A; Vilas-Zornoza A; Romero JP; Jonsson G; Oria R; Leopoldi A; Hagelkruys A; Moya-Rull D; González F; Marco A; Tarantino C; Domingo-Pedrol P; HasanAli O; Ventura-Aguiar P; María Campistol J; Prosper F; Mirazimi A; Boulant S; Penninger J; Montserrat N
Preprint: RESEARCH SQUARE. 2021
Longitudinal blood cell transcriptomic profiling and in vitro temporal proteomics provides novel insights into metabolic reprogramming and host-immune responses against Crimean-Congo Hemorrhagic Fever Virus
Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci B; Gupta S; Rodriguez J; Akusjärvi SS; Monteil V; Vegvari A; Banerjea A; Weber F; Hewson R; Mirazimi A
Preprint: BIORXIV. 2021
Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites
Hoffmann D; Mereiter S; Oh YJ; Monteil V; Zhu R; Canena D; Hain L; Laurent E; Grünwald-Gruber C; Novatchkova M; Ticevic M; Chabloz A; Wirnsberger G; Hagelkruys A; Altmann F; Mach L; Stadlmann J; Oostenbrink C; Mirazimi A; Hinterdorfer P; Penninger J
Preprint: BIORXIV. 2020
Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo Hemorrhagic Fever Viruses for novel therapeutic target
Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci B; Gupta S; Rodriguez J; Svensson-Akusjärvi S; Monteil V; Végvári Á; Benfeitas R; Banerjea A; Weber F; Hewson R; Mirazimi A
Preprint: MEDRXIV. 2020
Development and potential usefulness of the COVID-19 Ag Respi-Strip® diagnostic assay in a pandemic context
Mertens P; De Vos N; Martiny D; Jassoy C; Mirazimi A; Cuypers L; Van Den Wijngaert S; Monteil V; Melin P; Stoffels K; Yin N; Mileto D; Delaunoy S; Magein H; Lagrou K; Bouzet J; Serrano G; Wautier M; Leclipteux T; Van Ranst M; Vandenberg O; LHUB-ULB SARS-COV-2 working diagnostic group; Gulbis B; Brancart F; Bry F; Cantinieaux B; Corazza F; Cotton F; Dresselhuis M; Mahadeb B; Roels O; Vanderlinden J
Preprint: RESEARCH SQUARE. 2020
Mechanism of baricitinib supports artificial intelligence-predicted testing in COVID-19 patients
Stebbing J; Krishnan V; de Bono S; Ottaviani S; Casalini G; Richardson P; Monteil V; Lauschke V; Mirazimi A; Terres JR; Nickoloff B; Higgs R; Rocha G; Byers N; Schlichting D; Cardoso A; Corbellino M
Preprint: BIORXIV. 2020
Monoclonal antibodies for the S2 subunit of spike of SARS-CoV cross-react with the newly-emerged SARS-CoV-2
Zheng Z; Monteil V; Maurer-Stroh S; Yew CW; Leong C; Mohd-Ismail NK; Arularasu SC; Chow VTK; Pin RLT; Mirazimi A; Hong W; Tan Y-J
Conference publication: MOLECULAR THERAPY. 2020;28(4):61
Protection Against Crimean-Congo Hemorrhagic Fever Virus in a Cynomolgus Macaque Disease Model by Genetic Vaccination
Hawman D; Ahlen G; Appelberg S; White-Meade K; Hanley P; Scott D; Monteil V; Devignot S; Weber F; Feldmann H; Sallberg M; Mirazimi A
Letter: EMERGING MICROBES AND INFECTIONS. 2018;7(1):190-5
The DEVD motif of Crimean- Congo hemorrhagic fever virus nucleoprotein is essential for viral replication in tick cells
Salata C; Monteil V; Karlberg H; Celestino M; Devignot S; Leijon M; Bell-Sakyi L; Bergeron E; Weber F; Mirazimi A

Employments

Research Specialist, Department of Laboratory Medicine, Karolinska Institutet, 2025-
Laboratory Manager, Department of Laboratory Medicine, Karolinska Institutet, 2020-2024

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