Tulay Lindberg
About me
M.Sci - Stockholm University 1988
M.Med.Sc - Karolinska Institutet 1989
Ph.D - Karolinska Institutet 1999
Associate Professor - Karolinska Institutet 2007
Research
Periodontitis is a chronic inflammatory disease in which bacterial products,
host response, genetic and environmental factors are involved. It is
generally accepted that the bacterial products activate host
immunoinflammatory responses and subsequently the production of inflammatory
mediators, prostaglandins and proteolytic enzymes which, directly or
indirectly, contribute to the destruction of the periodontal tissues.
However, neither the precise molecular mechanism(s) nor the regulatory genes
underlying periodontitis are fully understood.
During past decades, reciprocal effects of periodontal disease have been
considered as factors potentially affecting the progression of other chronic
inflammatory diseases such as cardiovascular diseases, diabetes mellitus,
obesity, and rheumatoid arthritis. The underlying pathological mechanisms of
periodontitis and rheumatoid arthritis are strikingly similar although the
link, strength and temporality of the association is still not understood.Objectives of our research
- to identify predictive and diagnostic biomarkers for periodontitis and peri-implantitis
- to investigate the relationship between periodontitis/periodontal pathogens- and associated diseases such as rheumatoid arthritis and diabetes
- to study the interactions between oral microbiome and carcinogenesis Group members
Tülay Yucel-Lindberg – Associate professorCarina Fie – PhD student
Anders Lindunger – PhD student
Carl Lundgren– PhD student
Kaja Eriksson – associated
Anna Lundmark – associated
Anna Kats – associatedLuis Fernando Delgado Zambrano – associated
Research grants
The Swedish Research Council (Vetenskapsrådet)
The Patent Revenue Fund for Research in Preventive Odontology- (Patentmedelsfonden)
Stockholm County Council, KI/SLL for odontological research (SOF)
Stockholm County Council (ALF)
Reumatikerförbundet Dissertations
Tove Båge -- Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts [1]
Anna Kats - Expression of prostaglandin E synthase-1 in periodontitis:in vivo and in vitro studies [2]
Haleh Davanian - Gene expression profiling in periodontitis [3]
Kaja Eriksson - Studies on the relationship between periodontitis and - rheumatoid arthritis [4]
Anna Lundmark - Transcriptomic and taxonomic profiling of periodontitis by massively parallel sequencing [5]
[1] https://openarchive.ki.se/xmlui/handle/10616/40565
[2] https://openarchive.ki.se/xmlui/handle/10616/42003
[3] https://openarchive.ki.se/xmlui/handle/10616/44495
[4] https://openarchive.ki.se/xmlui/handle/10616/45935
[5] https://openarchive.ki.se/xmlui/handle/10616/45969
Articles
- Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2024;42(1):170-177
- Article: JOURNAL OF CLINICAL PERIODONTOLOGY. 2024;51(1):74-85
- Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(16):5325
- Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(12):4053
- Article: FRONTIERS IN MICROBIOLOGY. 2023;14:1172340
- Article: CANCERS. 2022;14(15):3826
- Article: PLOS ONE. 2022;17(10):e0276375
- Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2022;12:841139
- Article: JOURNAL OF CLINICAL MEDICINE. 2021;10(15):3413
- Article: CLINICAL ORAL IMPLANTS RESEARCH. 2021;32(5):559-568
- Article: TUMOR BIOLOGY. 2021;43(1):1-9
- Article: FRONTIERS IN IMMUNOLOGY. 2021;12:801096
- Article: SLEEP MEDICINE. 2020;67:7-14
- Article: BENEFICIAL MICROBES. 2019;10(6):653-659
- Article: JOURNAL OF CLINICAL MEDICINE. 2019;8(5):630
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2019;23(2):1152-1163
- Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2019;9:216
- Article: THERAPEUTIC ADVANCES IN MUSCULOSKELETAL DISEASE. 2019;11:1759720X19883152
- Article: BMC RESEARCH NOTES. 2018;11(1):759
- Article: BENEFICIAL MICROBES. 2018;9(5):691-696
- Article: JOURNAL OF ORAL PATHOLOGY & MEDICINE. 2018;47(8):764-772
- Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2018;16(1):214
- Article: SCIENTIFIC REPORTS. 2018;8(1):9370
- Article: BRITISH JOURNAL OF CANCER. 2018;118(3):428-434
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2017;75(7):524-529
- Article: PROBIOTICS AND ANTIMICROBIAL PROTEINS. 2017;9(3):278-283
- Article: JOURNAL OF CLINICAL PERIODONTOLOGY. 2017;44(3):247-254
- Article: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE. 2017;2017:2576548
- Article: SCIENTIFIC REPORTS. 2016;6:37137
- Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2016;14(1):311
- Article: ANNALS OF THE AMERICAN THORACIC SOCIETY. 2016;13(11):2002-2011
- Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2016;20(6):1128-1138
- Article: ARTHRITIS & RHEUMATOLOGY. 2016;68(3):604-613
- Article: EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE. 2016;2016:5357689
- Article: PLOS ONE. 2016;11(5):e0155956
- Article: SCIENTIFIC REPORTS. 2015;5:18475
- Article: SUPPORTIVE CARE IN CANCER. 2015;23(6):1749-1757
- Article: STEM CELL RESEARCH AND THERAPY. 2015;6(1):59
- Article: SLEEP. 2015;38(3):463-471
- Article: JOURNAL OF PERIODONTAL RESEARCH. 2014;49(6):742-750
- Article: BMC ORAL HEALTH. 2014;14:75
- Article: CLINICAL ORAL INVESTIGATIONS. 2014;18(2):359-368
- Article: JOURNAL OF PERIODONTAL RESEARCH. 2013;48(5):553-562
- Article: THE FASEB JOURNAL. 2013;27(6):2328-2341
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2013;71(3-4):828-833
- Article: CYTOKINE. 2012;57(3):406-416
- Article: CLINICAL ORAL INVESTIGATIONS. 2012;16(1):267-273
- Article: PLOS ONE. 2012;7(9):e46440
- Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2011;31(6):936-945
- Article: PEDIATRIC OBESITY. 2011;6(3-4):244-252
- Article: PEDIATRIC OBESITY. 2011;6(2-2):E264-E270
- Article: AMERICAN JOURNAL OF PATHOLOGY. 2011;178(4):1676-1688
- Article: NATURE REVIEWS. RHEUMATOLOGY. 2010;6(12):727-730
- Article: ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY. 2010;110(5):597-604
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2009;67(1):19-24
- Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2007;1773(10):1589-1598
- Article: CELLULAR SIGNALLING. 2006;18(12):2131-2142
- Article: ARCHIVES OF ORAL BIOLOGY. 2006;51(10):892-898
- Article: JOURNAL OF PERIODONTAL RESEARCH. 2006;41(2):108-117
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;338(4):1825-1833
- Article: REGULATORY PEPTIDES. 2005;126(3):183-188
- Article: JOURNAL OF CLINICAL PERIODONTOLOGY. 2005;32(1):6-11
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2004;62(5):273-277
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2004;62(5):269-272
- Article: JOURNAL OF PERIODONTAL RESEARCH. 2004;39(5):308-314
- Article: INFLAMMATION. 2004;28(2):89-95
- Article: JOURNAL OF PHARMACEUTICAL SCIENCES. 2003;92(8):1648-1653
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2003;61(4):193-196
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 2003;61(3):154-158
- Article: JOURNAL OF ENDOCRINOLOGY. 2002;175(1):165-176
- Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 2002;110(4):302-306
- Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 2001;109(3):187-192
- Article: INFLAMMATION. 2000;24(3):207-217
- Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1999;257(2):528-532
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 1999;57(1):40-45
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 1999;57(1):23-27
- Article: JOURNAL OF DENTAL RESEARCH. 1999;78(1):61-68
- Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 1998;106(1):571-575
- Article: ACTA ODONTOLOGICA SCANDINAVICA. 1997;55(2):101-105
- Article: EUROPEAN JOURNAL OF ORAL SCIENCES. 1996;104(1):27-33
- Article: INFLAMMATION. 1995;19(5):549-560
- Article: JOURNAL OF PERIODONTAL RESEARCH. 1995;30(3):186-191
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All other publications
- Conference publication: EUROPEAN RESPIRATORY JOURNAL. 2020;56:4740
- Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(8):1236-1238
- Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2018;77:A33
- Corrigendum: PROBIOTICS AND ANTIMICROBIAL PROTEINS. 2017;9(2):213
- Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2017;76:A92-A93
- Meeting abstract: ANNALS OF THE RHEUMATIC DISEASES. 2014;73:A73-A74
- Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2014;79(6):429
- Review: EXPERT REVIEWS IN MOLECULAR MEDICINE. 2013;15:e7
- Conference publication: JOURNAL OF DENTAL RESEARCH. 2003;82:B291
- Conference publication: JOURNAL OF DENTAL RESEARCH. 2003;82:B225
- Thesis / dissertation: 1999
- Conference publication: JOURNAL OF DENTAL RESEARCH. 1998;77(5):1328
- Conference publication: JOURNAL OF DENTAL RESEARCH. 1998;77:867
- Conference publication: JOURNAL OF DENTAL RESEARCH. 1997;76:312
Employments
- Researcher, Department of Dental Medicine, Karolinska Institutet, 2011-
Degrees and Education
- Docent, Karolinska Institutet, 2007
- Doctor Of Philosophy, Department of Dental Medicine, Karolinska Institutet, 1999