Tulay Lindberg

Tulay Lindberg

Researcher | Docent
Telephone: +46852488126
Visiting address: Alfred Nobels Allé 8, 14104 Huddinge
Postal address: OF Odontologi, OF Pedodonti, 171 77 Stockholm

About me

  • M.Sci - Stockholm University 1988
    M.Med.Sc - Karolinska Institutet 1989
    Ph.D - Karolinska Institutet 1999
    Associate Professor - Karolinska Institutet 2007


  • Periodontitis is a chronic inflammatory disease in which bacterial products,
    host response, genetic and environmental factors are involved. It is
    generally accepted that the bacterial products activate host
    immunoinflammatory responses and subsequently the production of inflammatory
    mediators, prostaglandins and proteolytic enzymes which, directly or
    indirectly, contribute to the destruction of the periodontal tissues.
    However, neither the precise molecular mechanism(s) nor the regulatory genes
    underlying periodontitis are fully understood.
    During past decades, reciprocal effects of periodontal disease have been
    considered as factors potentially affecting the progression of other chronic
    inflammatory diseases such as cardiovascular diseases, diabetes mellitus,
    obesity, and rheumatoid arthritis. The underlying pathological mechanisms of
    periodontitis and rheumatoid arthritis are strikingly similar although the
    link, strength and temporality of the association is still not understood.
    *Objectives of our research are:*
    - to identify predictive and diagnostic biomarkers for periodontitis
    - to develop anti-inflammatory agents targeting the enzyme prostaglandin E
    synthase for chronic inflammation
    - to investigate the relationship between periodontitis/periodontal pathogens
    and associated diseases such as rheumatoid arthritis and diabetes
    - to study the interactions between oral microbiome and carcinogenesis
    *Group members*
    Tülay Yucel-Lindberg – Associate professor
  • Carina Fie – PhD
  • Anders Lindunger – PhD student
  • Carl Lundgren– PhD
  • Kaja Eriksson – associated
  • Anna Lundmark – associated

Anna Kats – associated
  • Mehrad Mohammadi – KI’s summer research
  • Elizabeth Stenwall – KI’s summer research school
    *Research grants*
    The Swedish Research Council (Vetenskapsrådet)

  • The Patent Revenue Fund for Research in Preventive Odontology

  • Stockholm County Council, KI/SLL for odontological research (SOF)

  • Stockholm County Council (ALF)

  • Reumatikerförbundet
    *Tove Båge - * /*Prostaglandin E synthases in periodontitis-affected
    gingival tissue and in gingival fibroblasts [1]*/
    *Anna Kats - /Expression of prostaglandin E synthase-1 in periodontitis :
    in vivo and in vitro studies [2]/*
    *Haleh Davanian - /Gene expression profiling in periodontitis [3]/*
    *Kaja Eriksson - /Studies on the relationship between periodontitis and
    rheumatoid arthritis [4]/*
    *Anna Lundmark - /Transcriptomic and taxonomic profiling of periodontitis
    by massively parallel sequencing [5]/*
    [1] https://openarchive.ki.se/xmlui/handle/10616/40565
    [2] https://openarchive.ki.se/xmlui/handle/10616/42003
    [3] https://openarchive.ki.se/xmlui/handle/10616/44495
    [4] https://openarchive.ki.se/xmlui/handle/10616/45935
    [5] https://openarchive.ki.se/xmlui/handle/10616/45969


All other publications


  • Researcher, Department of Dental Medicine, Karolinska Institutet, 2011-

Degrees and Education

  • Docent, Karolinska Institutet, 2007
  • Doctor Of Philosophy, Department of Dental Medicine, Karolinska Institutet, 1999

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