Tulay Lindberg

Tulay Lindberg

Researcher | Docent
Telephone: +46852488126
Visiting address: Alfred Nobels Allé 8, 14104 Huddinge
Postal address: OF Odontologi, OF Pedodonti, 171 77 Stockholm

About me

  • M.Sci - Stockholm University 1988 M.Med.Sc - Karolinska Institutet 1989 Ph.D - Karolinska Institutet 1999 Associate Professor - Karolinska Institutet 2007

Research

  • Periodontitis is a chronic inflammatory disease in which bacterial products, host response, genetic and environmental factors are involved. It is generally accepted that the bacterial products activate host immunoinflammatory responses and subsequently the production of inflammatory mediators, prostaglandins and proteolytic enzymes which, directly or indirectly, contribute to the destruction of the periodontal tissues. However, neither the precise molecular mechanism(s) nor the regulatory genes underlying periodontitis are fully understood. During past decades, reciprocal effects of periodontal disease have been considered as factors potentially affecting the progression of other chronic inflammatory diseases such as cardiovascular diseases, diabetes mellitus, obesity, and rheumatoid arthritis. The underlying pathological mechanisms of periodontitis and rheumatoid arthritis are strikingly similar although the link, strength and temporality of the association is still not understood. *Objectives of our research are:* - to identify predictive and diagnostic biomarkers for periodontitis - to develop anti-inflammatory agents targeting the enzyme prostaglandin E synthase for chronic inflammation - to investigate the relationship between periodontitis/periodontal pathogens and associated diseases such as rheumatoid arthritis and diabetes - to study the interactions between oral microbiome and carcinogenesis *Group members* Tülay Yucel-Lindberg – Associate professor
  • Carina Fie – PhD student
  • Anders Lindunger – PhD student
  • Carl Lundgren– PhD student
  • Kaja Eriksson – associated
  • Anna Lundmark – associated
  • Anna Kats – associated
  • Mehrad Mohammadi – KI’s summer research school
  • Elizabeth Stenwall – KI’s summer research school *Research grants* The Swedish Research Council (Vetenskapsrådet)
  • The Patent Revenue Fund for Research in Preventive Odontology (Patentmedelsfonden)
  • Stockholm County Council, KI/SLL for odontological research (SOF)
  • Stockholm County Council (ALF)
  • Reumatikerförbundet *Dissertations* *Tove Båge - * /*Prostaglandin E synthases in periodontitis-affected gingival tissue and in gingival fibroblasts [1]*/ *Anna Kats - /Expression of prostaglandin E synthase-1 in periodontitis : in vivo and in vitro studies [2]/* *Haleh Davanian - /Gene expression profiling in periodontitis [3]/* *Kaja Eriksson - /Studies on the relationship between periodontitis and rheumatoid arthritis [4]/* *Anna Lundmark - /Transcriptomic and taxonomic profiling of periodontitis by massively parallel sequencing [5]/* [1] https://openarchive.ki.se/xmlui/handle/10616/40565 [2] https://openarchive.ki.se/xmlui/handle/10616/42003 [3] https://openarchive.ki.se/xmlui/handle/10616/44495 [4] https://openarchive.ki.se/xmlui/handle/10616/45935 [5] https://openarchive.ki.se/xmlui/handle/10616/45969

Articles

All other publications

Employments

  • Researcher, Department of Dental Medicine, Karolinska Institutet, 2011-

Degrees and Education

  • Docent, Karolinska Institutet, 2007
  • Doctor Of Philosophy, Department of Dental Medicine, Karolinska Institutet, 1999

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