Tong Jiao

Publications
CV
Public outreach and news

Articles

Journal article: BRITISH JOURNAL OF PHARMACOLOGY. 2024
miR-210 as a therapeutic target in diabetes-associated endothelial dysfunction
Collado A; Jiao T; Kontidou E; Carvalho LRRA; Chernogubova E; Yang J; Zaccagnini G; Zhao A; Tengbom J; Zheng X; Rethi B; Alvarsson M; Catrina S-B; Mahdi A; Carlstroem M; Martelli F; Pernow J; Zhou Z
Journal article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2024
Red blood cells from patients with ST-elevation myocardial infarction and elevated C-reactive protein levels induce endothelial dysfunction.
Tengbom J; Humoud R; Kontidou E; Jiao T; Yang J; Hedin U; Zhou Z; Jurga J; Collado A; Mahdi A; Pernow J
Journal article: PARKINSONISM & RELATED DISORDERS. 2024;128:107121
Vascular disease and risk of fall-related injuries in Parkinson's disease: A nationwide cohort study in Sweden
Kang X; Jiao T; Tan B; Larsson H; Wirdefeldt K
Journal article: CARDIOVASCULAR RESEARCH. 2024;120:cvae088.035
Red blood cell-derived extracellular vesicles from type 2 diabetes patients induce endothelial dysfunction through a mechanism involving arginase 1
Collado A; Humoud R; Kontidou E; Eldh M; Yang J; Jiao T; Domingo E; Mahdi A; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Journal article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2024;44(Suppl_1)
Abstract 1127: Erythrocyte Derived Extracellular Vesicles From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Through Increased Vascular Oxidative Stress
Collado A; Humoud R; Kontidou E; Yang J; Jiao T; Mahdi A; Zhou Z; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3099
Paracrine cardioprotective signaling by red blood cells through hypoxia-mediated activation of soluble guanylate cyclase and release of cyclic guanosine monophosphate
Yang JN; Sundqvist M; Zheng X; Jiao T; Collado A; Mahdi A; Tengbom J; Mergia E; Zhou Z; Carlstrom M; Akaike T; Cortese-Krott M; Weitzberg E; Lundberg JO; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3096
Stimulation of soluble guanylyl cyclase in erythrocytes induces export of cGMP and cardioprotection in type 2 diabetes
Jiao T; Collado A; Mahdi A; Tengbom J; Tratsiakovich Y; Milne G; Alvarsson M; Lundberg J; Zhou Z; Yang J; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2023;44:ehad655.3066
Erythrocyte-derived extracellular vesicles from type 2 diabetes patients induce endothelial dysfunction through arginase 1
Collado A; Humoud R; Eldh M; Jiao T; Domingo E; Kontidou E; Yang J; Mahdi A; Gabrielsson S; Eriksson P; Zhou Z; Pernow J
Article: JOURNAL OF CLINICAL INVESTIGATION. 2023;133(17):e167693
Hypoxic erythrocytes mediate cardioprotection through activation of soluble guanylate cyclase and release of cyclic GMP
Yang J; Sundqvist ML; Zheng X; Jiao T; Collado A; Tratsiakovich Y; Mahdi A; Tengbom J; Mergia E; Catrina S-B; Zhou Z; Carlstroem M; Akaike T; Cortese-Krott MM; Weitzberg E; Lundberg JO; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2023;8(8):907-918
Stimulation of Erythrocyte Soluble Guanylyl Cyclase Induces cGMP Export and Cardioprotection in Type 2 Diabetes
Jiao T; Collado A; Mahdi A; Tengbom J; Tratsiakovich Y; Milne GT; Alvarsson M; Lundberg JO; Zhou Z; Yang J; Pernow J
Article: JOURNAL OF INTERNAL MEDICINE. 2023;293(2):228-245
The red blood cell as a mediator of endothelial dysfunction in patients with familial hypercholesterolemia and dyslipidemia
Mahdi A; Wodaje T; Kovamees O; Tengbom J; Zhao A; Jiao T; Henricsson M; Yang J; Zhou Z; Nieminen AI; Levin M; Collado A; Brinck J; Pernow J
Article: BASIC RESEARCH IN CARDIOLOGY. 2022;117(1):46
Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection through the purinergic P2Y₁₃ receptor and nitric oxide signaling
Jiao T; Collado A; Mahdi A; Jurga J; Tengbom J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2022;7(3):193-204
Erythrocytes Induce Vascular Dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johansson N; Farnebo F; Farnert A; Yang J; Lundberg JO; Zhou Z; Pernow J
Article: EBIOMEDICINE. 2022;76:103824
Mendelian randomization study on the causal effects of tumor necrosis factor inhibition on coronary artery disease and ischemic stroke among the general population
Kang X; Jiao T; Wang H; Pernow J; Wirdefeldt K
Article: DIABETES. 2022;71(2):285-297
Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes
Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: PHARMACOLOGY. 2022;107(3-4):160-166
Therapeutic Potential of Sunitinib in Ameliorating Endothelial Dysfunction in Type 2 Diabetic Rats
Mahdi A; Jiao T; Tratsiakovich Y; Wernly B; Yang J; Ostenson C-G; Danser AHJ; Pernow J; Zhou Z
Journal article: EUROPEAN HEART JOURNAL. 2021;42(Supplement_1):ehab724.3364
Erythrocytes induce vascular dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:603226
Erythrocytes Induce Endothelial Injury in Type 2 Diabetes Through Alteration of Vascular Purinergic Signaling
Mahdi A; Tratsiakovich Y; Tengbom J; Jiao T; Garib L; Alvarsson M; Yang J; Pernow J; Zhou Z
Journal article: EUROPEAN HEART JOURNAL. 2019;40(Supplement_1):ehz748.0351
P1592A cardioprotective effect of dietary nitrate mediated by red blood cells
Jiao T; Yang JN; Sundqvist M; Tratsiakovich Y; Hellenius ML; Weitzberg E; Lundberg J; Pernow J
Journal article: EUROPEAN HEART JOURNAL. 2019;40(Supplement_1):ehz746.0897
P6299Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells
Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J
Article: JOURNAL OF PHARMACOLOGICAL SCIENCES. 2019;141(1):64-69
Activation of adenosine A_2A but not A_2B receptors is involved in uridine adenosine tetraphosphate-induced porcine coronary smooth muscle relaxation
Sun C; Jiao T; Merkus D; Duncker DJ; Mustafa SJ; Zhou Z
Journal article: FASEB JOURNAL. 2019;33:512.4
Sunitinib Improves Endothelial Function in Type 2 Diabetic Rats
Zhou Z; Mahdi A; Tratsiakovich Y; Jiao T; Yang J; Ostenson C-G; Danser AHJ; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:861
The Effect of Glycemic Control on Endothelial and Cardiac Dysfunction Induced by Red Blood Cells in Type 2 Diabetes
Mahdi A; Jiao T; Yang J; Kovamees O; Alvarsson M; von Heijne M; Zhou Z; Pernow J
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2018;19(12):E3942-3942
Altered Purinergic Receptor Sensitivity in Type 2 Diabetes-Associated Endothelial Dysfunction and Up₄A-Mediated Vascular Contraction
Mahdi A; Jiao T; Tratsiakovich Y; Yang J; Ostenson C-G; Pernow J; Zhou Z
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):450-463
Red Blood Cells in Type 2 Diabetes Impair Cardiac Post-Ischemic Recovery Through an Arginase-Dependent Modulation of Nitric Oxide Synthase and Reactive Oxygen Species
Yang J; Zheng X; Mahdi A; Zhou Z; Tratsiakovich Y; Jiao T; Kiss A; Kovamees O; Alvarsson M; Catrina S-B; Lundberg JO; Brismar K; Pernow J
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Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2917
Red blood cells induce endothelial dysfunction in patients with ST-elevation myocardial infarction and elevated C-reactive protein
Tengbom J; Collado A; Jiao T; Yang J; Zhou Z; Mahdi A; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2921
Arginase 1 in erythrocytes is a critical modulator of cardioprotective signalling by nitric oxide and soluble guanylyl cyclase
Yang JN; Tratsiakovich YT; Jiao TJ; Mahdi AM; Tengbom JT; Zhou ZZ; Collado AC; Lundberg JL; Pernow JP
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:2910
Erythrocytes from patients with ST-elevation myocardial infarction induce cardioprotection via the purinergic P2Y13 receptor and nitric oxide signalling
Jiao T; Mahdi A; Tengbom J; Collado A; Jurga J; Saleh N; Verouhis D; Bohm F; Zhou Z; Yang J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2022;43:3074
Overexpression of miR-210 ameliorates endothelial dysfunction in type 2 diabetic mice
Collado A; Jiao T; Zaccagnini G; Yang J; Carstrom M; Martelli F; Pernow J; Zhou Z
Thesis / dissertation: 2022
The role of red blood cells in cardiac and endothelial dysfunction in cardiometabolic disease
Jiao, Tong
Conference publication: DIABETOLOGIA. 2022;65(SUPPL 1):S25
Overexpression of miR-210 attenuates endothelial dysfunction in a mouse model of obesity and type 2 diabetes
Collado A; Jiao T; Zaccagnini G; Yang J; Carlstrom M; Martelli F; Pernow J; Zhou Z
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3259
Attenuated cardiac post-ischemic injury and endothelial dysfunction by stimulation of soluble guanylyl cyclase in red blood cells from patients with type 2 diabetes
Jiao T; Zhou Z; Mahdi A; Tengbom J; Tratsiakovich Y; Yang J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2021;42:3364
Erythrocytes induce vascular dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Yang J; Lundberg JO; Zhou Z; Pernow J
Preprint: SSRN. 2021
Erythrocytes Induce Vascular Dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johanssson N; Farnebo F; Färnert A; Yang J; Lundberg J; Zhou Z; Pernow J
Preprint: SSRN ELECTRONIC JOURNAL. 2021
Erythrocytes Induce Vascular Dysfunction in COVID-19
Mahdi A; Collado A; Tengbom J; Jiao T; Wodaje T; Johanssson N; Farnebo F; Färnert A; Yang J; Lundberg JO; Zhou Z; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:894
A cardioprotective effect of dietary nitrate mediated by red blood cells
Jiao T; Yang JN; Sundqvist M; Tratsiakovich Y; Hellenius ML; Weitzberg E; Lundberg J; Pernow J
Conference publication: EUROPEAN HEART JOURNAL. 2019;40:3903
Dietary nitrate restores cardiac ischemic tolerance in type 2 diabetic mice and protects against ischemia-reperfusion injury via soluble guanylate cyclase in red blood cells
Yang JN; Jiao T; Tratsiakovich Y; Mahdi A; Zhou Z; Lundberg JO; Pernow J

Employments

Postdoctoral Researcher, Department of Medicine, Karolinska Institutet, 2024-2026
Affiliated to Research, Department of Medicine, Karolinska Institutet, 2022-2024

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2022

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