Thomas Poiret

About me
Publications
CV
Public outreach and news

About me

I am a biträdande lektor (assistant professor) in the Division led by Michael Uhlin (HERM, MedH, Huddinge campus).

Research

My main research interests are i) T cell based immunotherapy such as chimeric antigen receptor (CAR) therapy for hematological malignancies and solid tumor, ii) gamma-delta (γδ) T cells and the involvement of their different subsets in the clinical setting of cancer and infections and iii) harness the innate and cross-presentation properties of γδ T cells for immune therapy purpose.

My second focus is the sustainable development of research and diagnosis (mainly immunology but not exclusively) in low- and middle- income countries (LMICs). I work together the Pasteur Network of Senegal and Madagascar to support capacity building and promote clinical research excellence.

Teaching

Laboratory training and supervision of biomedical analyst students, biology master students, medical interns and PhD students at Karolinska Institutet and Pasteur Institute of Dakar, Senegal.
PhD course co-organizer and teaching for "Antigen presentation and T cell activation"
Teaching for biomedical analyst students (Immunology) and PhD students at Pasteur Institute of Dakar, Senegal (Basic immunological techniques and Immunology)

Articles

Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):273
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different magnitude
Poiret T; Vikberg S; Schoutrop E; Mattsson J; Magalhaes I
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2024;22(1):250
Inducing expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy
Saffarzadeh N; Foord E; O'Leary E; Mahmoun R; Hansen TB; Levitsky V; Poiret T; Uhlin M
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(2):e005691
Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models
Schoutrop E; Poiret T; El-Serafi I; Zhao Y; He R; Moter A; Henriksson J; Hassan M; Magalhaes I; Mattsson J
Article: SCIENTIFIC REPORTS. 2023;13(1):782
Linear epitope mapping of the humoral response against SARS-CoV-2 in two independent African cohorts
Vigan-Womas I; Spadoniz J-L; Poiretz T; Taieb F; Randrianarisaona F; Faye R; Mbow AA; Gaye A; Dia N; Loucoubar C; Mioramalala DJN; Ratovoson R; Randremanana RV; Sall AA; Seydi M; Noirel J; Moreau G; Simon A; Holenye P; Meyniel J-P; Zagury J-F; Schoenhals M
Article: ONCOIMMUNOLOGY. 2022;11(1):2093426
Trogocytosis and fratricide killing impede MSLN-directed CAR T cell functionality
Schoutrop E; Renken S; Micallef Nilsson I; Hahn P; Poiret T; Kiessling R; Wickstrom SL; Mattsson J; Magalhaes I
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1027593
Different recovery patterns of CMV-specific and WT1-specific T cells in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: Impact of CMV infection and leukemia relapse
Luo X-H; Poiret T; Liu Z; Meng Q; Nagchowdhury A; Ljungman P
Article: CANCER RESEARCH. 2021;81(11):3022-3035
Mesothelin-Specific CAR T Cells Target Ovarian Cancer
Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: VACCINES. 2020;8(4):E630-630
Mass Spectrometric Characterization of Narcolepsy-Associated Pandemic 2009 Influenza Vaccines
Ambati A; Luo G; Pradhan E; Louis J; Lin L; Leib RD; Ollila HM; Poiret T; Adams C; Mignot E
Article: JOURNAL OF TRANSLATIONAL MEDICINE. 2018;16(1):182
Epstein-Barr virus- and cytomegalovirus-specific immune response in patients with brain cancer
Liu Z; Poiret T; Meng Q; Rao M; von Landenberg A; Schoutrop E; Valentini D; Dodoo E; Peredo-Harvey I; Maeurer M
Article: CANCER IMMUNOLOGY, IMMUNOTHERAPY. 2018;67(2):237-246
NY-ESO-1-and survivin-specific T-cell responses in the peripheral blood from patients with glioma
Liu Z; Poiret T; Persson O; Meng Q; Rane L; Bartek JJ; Karbach J; Altmannsberger H-M; Illies C; Luo X; Harvey-Peredo I; Jaeger E; Dodoo E; Maeurer M
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:760
Cytomegalovirus-Specific CD8+T-Cells With Different T-Cell Receptor Affinities Segregate T-Cell Phenotypes and Correlate With Chronic Graft-Versus-Host Disease in Patients Post-Hematopoietic Stem Cell Transplantation
Poiret T; Axelsson-Robertson R; Remberger M; Luo X-H; Rao M; Nagchowdhury A; Von Landenberg A; Ernberg I; Ringden O; Maeurer M
Article: ONCOTARGET. 2017;8(46):80208-80222
Mesothelin as a novel biomarker and immunotherapeutic target in human glioblastoma
Liu Z; Rao M; Poiret T; Nava S; Meng Q; von Landenberg A; Bartek JJ; Xie S; Sinclair G; Peredo I; Dodoo E; Maeurer M
Article: EBIOMEDICINE. 2017;23:20-24
Mesothelin-specific Immune Responses Predict Survival of Patients With Brain Metastasis
Liu Z; Rao M; Luo X; Sandberg E; Bartek JJ; Schoutrop E; von Landenberg A; Meng Q; Valentini D; Poiret T; Sinclair G; Peredo I-H; Dodooa E; Maeurer M
Article: JOURNAL OF IMMUNOTHERAPY. 2017;40(4):132-139
A Preliminary Report: Radical Surgery and Stem Cell Transplantation for the Treatment of Patients With Pancreatic Cancer
Omazic B; Ayoglu B; Lohr M; Segersvard R; Verbeke C; Magalhaes I; Potacova Z; Mattsson J; Terman A; Ghazi S; Albiin N; Kartalis N; Nilsson P; Poiret T; Liu Z; Heuchel R; Schwenk JM; Permert J; Maeurer MJ; Ringden O
Article: ONCOIMMUNOLOGY. 2017;6(2):e1252894
Tumor-infiltrating lymphocytes (TILs) from patients with glioma
Liu Z; Meng Q; Bartek JJ; Poiret T; Persson O; Rane L; Rangelova E; Illies C; Peredo IH; Luo X; Rao MV; Robertson RA; Dodoo E; Maeurer M
Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1861
Mucosal-associated invariant T cells Display a Poor reconstitution and altered Phenotype after allogeneic hematopoietic stem cell Transplantation
Solders M; Erkers T; Gorchs L; Poiret T; Remberger M; Magalhaes I; Kaipe H
Article: ONCOTARGET. 2016;7(21):30230-30240
Both high and low levels of cellular Epstein-Barr virus DNA in blood identify failure after hematologic stem cell transplantation in conjunction with acute GVHD and type of conditioning
Li Q; Rane L; Poiret T; Zou J; Magalhaes I; Ahmed R; Du Z; Vudattu N; Meng Q; Gustafsson-Jernberg A; Winiarski J; Ringden O; Maeurer M; Remberger M; Ernberg I
Article: JOURNAL OF IMMUNOTHERAPY. 2016;39(2):81-89
Expansion of Tumor-reactive T Cells From Patients With Pancreatic Cancer
Meng Q; Liu Z; Rangelova E; Poiret T; Ambati A; Rane L; Xie S; Verbeke C; Dodoo E; Del Chiaro M; Lohr M; Segersvard R; Maeurer MJ
Article: CLINICAL INFECTIOUS DISEASES. 2015;61(Suppl 3):S225-S234
B in TB: B Cells as Mediators of Clinically Relevant Immune Responses in Tuberculosis
Rao M; Valentini D; Poiret T; Dodoo E; Parida S; Zumla A; Brighenti S; Maeurer M
Article: CLINICAL INFECTIOUS DISEASES. 2015;61(Suppl 3):S217-S224
T-Cell Therapy: Options for Infectious Diseases
Parida SK; Poiret T; Zhenjiang L; Meng Q; Heyckendorf J; Lange C; Ambati AS; Rao MV; Valentini D; Ferrara G; Rangelova E; Dodoo E; Zumla A; Maeurer M
Article: JOURNAL OF INTERNAL MEDICINE. 2015;278(3):264-276
Increased -haemolytic group A streptococcal M6 serotype and streptodornase B-specific cellular immune responses in Swedish narcolepsy cases
Ambati A; Poiret T; Svahn B-M; Valentini D; Khademi M; Kockum I; Lima I; Arnheim-Dahlstrom L; Lamb F; Fink K; Meng Q; Kumar A; Rane L; Olsson T; Maeurer M
Article: TRANSPLANT INFECTIOUS DISEASE. 2015;17(3):371-379
Immunogenicity of virosomal adjuvanted trivalent influenza vaccination in allogeneic stem cell transplant recipients
Ambati A; Einarsdottir S; Magalhaes I; Poiret T; Bodenstein R; LeBlanc K; Brune M; Maeurer M; Ljungman P
Article: JOURNAL OF IMMUNOTHERAPY. 2014;37(8):416-425
TCR⁺CD4^-CD8^- T cells in Antigen-specific MHC Class I-restricted T-cell Responses After Allogeneic Hematopoietic Stem Cell Transplantation
Ahmed RK; Poiret T; Ambati A; Rane L; Remberger M; Omazic B; Vudattu NK; Winiarski J; Ernberg I; Axelsson-Robertson R; Magalhaes I; Castelli C; Ringden O; Maeurer M
Article: BMC IMMUNOLOGY. 2014;15:25
Reduced plasma levels of soluble interleukin-7 receptor during graft-versus-host disease (GVHD) in children and adults
Poiret T; Rane L; Remberger M; Omazic B; Gustafsson-Jernberg A; Vudattu NK; Ahmed R; Ernberg I; Winiarski J; Magalhaes I; Ringden O; Maeurer M
Article: THE LANCET RESPIRATORY MEDICINE. 2014;2(2):108-122
Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial
Skrahin A; Ahmed RK; Ferrara G; Rane L; Poiret T; Isaikina Y; Skrahina A; Zumla A; Maeurer MJ
Article: PLOS ONE. 2014;9(4):e89648
Whole CMV Proteome Pattern Recognition Analysis after HSCT Identifies Unique Epitope Targets Associated with the CMV Status
Perez-Bercoff L; Valentini D; Gaseitsiwe S; Mahdavifar S; Schutkowski M; Poiret T; Perez-Bercoff A; Ljungman P; Maeurer MJ
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All other publications

Preprint: RESEARCH SQUARE. 2024
Inducing the expression of ICOS-L by oncolytic adenovirus to enhance tumor-specific bi-specific antibody efficacy
Saffarzadeh N; Foord E; O'Leary E; Mahmoun R; Hansen T; Levitsky V; Poiret T; Uhlin M
Preprint: RESEARCH SQUARE. 2023
CAR T cells and T cells phenotype and function are impacted by glucocorticoid exposure with different amplitude.
Poiret T; Vikberg S; Schoutrop E; Mattsson J; Magalhaes I
Corrigendum: FRONTIERS IN IMMUNOLOGY. 2023;14:1195142
Different recovery patterns of CMV-specific and WT1-specific T cells in patients with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation: impact of CMV infection and leukemia relapse (vol 13, 1027593, 2023)
Luo X-H; Poiret T; Liu Z; Meng Q; Nagchowdhury A; Ljungman P
Preprint: BIORXIV. 2020
Mass Spectrometric Characterization of Narcolepsy-Associated Pandemic 2009 Influenza Vaccines
Ambati A; Luo G; Pradhan E; Louis J; Lin L; Lieb R; Ollila HM; Poiret T; Adams C; Mignot E
Editorial comment: BRITISH JOURNAL OF HAEMATOLOGY. 2019;187(2):139-140
Toward the understanding of a successful virus-specific T-cell therapy: T-cell receptor sequencing demonstrates persistence of virus-specific T cells after antiviral immunotherapy
Poiret T
Thesis / dissertation: 2018
Diversity and focus of CMV specific T-cell responses in patients post-HSCT and with solid tumor
Poiret, Thomas

Employments

Assistant Professor, Department of Medicine, Huddinge, Karolinska Institutet, 2024-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2018

About me

Research

Teaching

Articles

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Degrees and Education

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