Takuya Sekine

Publications
Public outreach and news

Articles

Article: GENES AND IMMUNITY. 2024;:1-5
The HLA-B-21 M/T dimorphism associates with disease severity in COVID-19
Strunz B; Momayyezi P; Bilev E; Muvva JR; Chen P; Bister J; Schaffer M; Akber M; Cornillet M; Horowitz A; Malmberg K-J; Rooyackers O; Aleman S; Ljunggren H-G; Bjorkstrom NK; Stralin K; Hammer Q; Berglin L; Bergsten H; Brighenti S; Brownlie D; Buggert M; Butrym M; Chambers BJ; Cuapio A; Lozano ID; Dillner L; Djarv T; Dzidic M; Emgard J; Eriksson LI; Flodstrom-Tullberg M; Glans H; Gorin J-B; Grip J; Haroun-Izquierdo A; Henriksson E; Hertwig L; Kalsum S; Kammann T; Klingstroem J; Kokkinou E; Kvedaraite E; Loreti MG; Lourda M; Maleki KT; Marquardt N; Martensson J; Maucourant C; Michaelsson J; Mjosberg J; Moll K; Naucler P; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Persson BP; Radler L; Religa D; Ringqvist E; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Sohlberg E; Soini T; Soennerborg A; Svensson M; Tynell J; Unge C; Varnaite R; von Kries A; Wullimann D
Article: SCIENCE IMMUNOLOGY. 2024;9(99):eadn2362
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles
Kammann T; Cai C; Sekine T; Mouchtaridi E; Boulouis C; Nilsen V; Ballesteros OR; Mueller TR; Gao Y; Raineri EJM; Mily A; Adamo S; Constantz C; Niessl J; Weigel W; Kokkinou E; Stamper C; Marchalot A; Bassett J; Ferreira S; Rodahl I; Wild N; Brownlie D; Tibbitt C; Mak JYW; Fairlie DP; Leeansyah E; Michaelsson J; Marquardt N; Mjosberg J; Jorns C; Buggert M; Sandberg JK
Article: BLOOD. 2024;144(8):873-887
Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis.
Chiang SCC; Covill LE; Tesi B; Campbell TM; Schlums H; Nejati-Zendegani J; Mördrup K; Wood S; Theorell J; Sekine T; Al-Herz W; Akar HH; Belen FB; Chan MY; Devecioglu O; Aksu T; Ifversen M; Malinowska I; Sabel M; Unal E; Unal S; Introne WJ; Krzewski K; Gilmour KC; Ehl S; Ljunggren H-G; Nordenskjöld M; Horne A; Henter J-I; Meeths M; Bryceson YT
Article: JOURNAL OF IMMUNOLOGY. 2024;212(3):389-396
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies
Kammann T; Gorin J-B; Parrot T; Gao Y; Ponzetta A; Emgard J; Maleki KT; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Skagerberg M; Eriksson LI; Norrby-Teglund A; Mak JYW; Fairlie DP; Bjorkstrom NK; Klingstrom J; Ljunggren H-G; Aleman S; Buggert M; Stralin K; Sandberg JK
Article: SCIENCE TRANSLATIONAL MEDICINE. 2023;15(704):eadg9452
Additive effects of booster mRNA vaccination and SARS-CoV-2 Omicron infection on T cell immunity across immunocompromised states
Muller TRR; Sekine T; Trubach D; Niessl J; Chen P; Bergman P; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Olofsson A; Hernandez SPA; Gao Y; Cai C; Soderdahl G; Smith CIE; Osterborg A; Lore K; Sallberg Chen M; Ljungman P; Ljunggren H-G; Karlsson ACC; Saini SK; Aleman S; Buggert M
Article: CELL HOST AND MICROBE. 2023;31(6):928-936.e4
Memory profiles distinguish cross-reactive and virus-specific T cell immunity to mpox
Adamo S; Gao Y; Sekine T; Mily A; Wu J; Storgard E; Westergren V; Filen F; Sandberg JK; Sallberg M; Bergman P; Llewellyn-Lacey S; Ljunggren H-G; Price DA; Ekstrom A-M; Sette A; Grifoni A; Buggert M
Article: NATURE COMMUNICATIONS. 2023;14(1):1438
An integrated single cell and spatial transcriptomic map of human white adipose tissue
Massier L; Jalkanen J; Elmastas M; Zhong J; Wang T; Nankam PAN; Frendo-Cumbo S; Backdahl J; Subramanian N; Sekine T; Kerr AG; Tseng BTP; Laurencikiene J; Buggert M; Lourda M; Kublickiene K; Bhalla N; Andersson A; Valsesia A; Astrup A; Blaak EE; Stahl PL; Viguerie N; Langin D; Wolfrum C; Blueher M; Ryden M; Mejhert N
Article: IMMUNITY. 2022;55(9):1732-1746.e5
Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination
Gao Y; Cai C; Wullimann D; Niessl J; Rivera-Ballesteros O; Chen P; Lange J; Cuapio A; Blennow O; Hansson L; Mielke S; Nowak P; Vesterbacka J; Akber M; Perez-Potti A; Sekine T; Muller TR; Boulouis C; Kammann T; Parrot T; Muvva JR; Sobkowiak M; Healy K; Bogdanovic G; Muschiol S; Soderdahl G; Osterborg A; Hellgren F; Grifoni A; Weiskopf D; Sette A; Lore K; Chen MS; Ljungman P; Sandberg JK; Smith CIE; Bergman P; Ljunggren H-G; Aleman S; Buggert M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2022;96(1):e13195
The Karolinska KI/K COVID-19 immune atlas: An open resource for immunological research and educational purposes
Ljunggren H-G; Heggernes Ask E; Cornillet Jeannin M; Strunz B; Chen P; Rao Muvva J; Akber M; Buggert M; Chambers BJ; Cuapio Gomez A; Dzidic M; Filipovic I; Flodstrom-Tullberg M; Garcia M; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Palma Medina LM; Parrot T; Perez-Potti A; Ponzetta A; Ringqvist E; Rivera-Ballesteros O; Rooyackers O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Wullimann D; Eriksson LI; Aleman S; Malmberg K-J; Stralin K; Bjorkstrom NK
Article: CELL REPORTS. 2022;38(10):110503
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Hammer Q; Dunst J; Christ W; Picarazzi F; Wendorff M; Momayyezi P; Huhn O; Netskar HK; Maleki KT; Garcia M; Sekine T; Sohlberg E; Azzimato V; Aouadi M; Degenhardt F; Franke A; Spallotta F; Mori M; Michaelsson J; Bjorkstrom NK; Rueckert T; Romagnani C; Horowitz A; Klingstrom J; Ljunggren H-G; Malmberg K-J
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2022;52(3):503-510
COVID-19-specific metabolic imprint yields insights into multiorgan system perturbations
Cornillet M; Strunz B; Rooyackers O; Ponzetta A; Chen P; Muvva JR; Akber M; Buggert M; Chambers BJ; Dzidic M; Filipovic I; Gorin J-B; Gredmark-Russ S; Hertwig L; Klingstrom J; Kokkinou E; Kvedaraite E; Lourda M; Mjosberg J; Maucourant C; Norrby-Teglund A; Parrot T; Perez-Potti A; Rivera-Ballesteros O; Sandberg JK; Sandberg JT; Sekine T; Svensson M; Varnaite R; Eriksson LI; Aleman S; Stralin K; Ljunggren H-G; Bjorkstrom NK
Article: SCIENCE IMMUNOLOGY. 2021;6(64):eabk0894
Identification of resident memory CD8⁺ T cells with functional specificity for SARS-CoV-2 in unexposed oropharyngeal lymphoid tissue
Niessl J; Sekine T; Lange J; Konya V; Forkel M; Maric J; Rao A; Mazzurana L; Kokkinou E; Weigel W; Llewellyn-Lacey S; Hodcroft EB; Karlsson AC; Fehrm J; Sundman J; Price DA; Mjosberg J; Friberg D; Buggert M
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118
Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity
Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Myrberg IH; Lourda M; Dzidic M; Akber M; Klingstrom J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Stralin K; Ljunggren H-G; Ginhoux F; Bjorkstrom NK; Henter J-I; Svensson M
Article: CLINICAL & TRANSLATIONAL IMMUNOLOGY. 2021;10(7):e1306
SARS-CoV-2-specific humoral and cellular immunity persists through 9 months irrespective of COVID-19 severity at hospitalisation
Sandberg JT; Varnaite R; Christ W; Chen P; Muvva JR; Maleki KT; Garcia M; Dzidic M; Folkesson E; Skagerberg M; Ahlen G; Frelin L; Sallberg M; Eriksson LI; Rooyackers O; Sonnerborg A; Buggert M; Bjorkstrom NK; Aleman S; Stralin K; Klingstrom J; Ljunggren H-G; Blom K; Gredmark-Russ S
Article: CELL. 2020;183(7):1946-1961.e15
The Identity of Human Tissue-Emigrant CD8⁺ T Cells
Buggert M; Vella LA; Nguyen S; Wu VH; Chen Z; Sekine T; Perez-Potti A; Maldini CR; Manne S; Darko S; Ransier A; Kuri-Cervantes L; Japp AS; Brody IB; Ivarsson MA; Gorin J-B; Rivera-Ballesteros O; Hertwig L; Antel JP; Johnson ME; Okoye A; Picker L; Vahedi G; Sparrelid E; Llewellyn-Lacey S; Gostick E; Sandberg JK; Bjorkstrom N; Bar-Or A; Dori Y; Naji A; Canaday DH; Laufer TM; Wells AD; Price DA; Frank I; Douek DC; Wherry EJ; Itkin MG; Betts MR
Article: JOURNAL OF PEDIATRIC HEMATOLOGY/ONCOLOGY. 2020;42(7):e627-e629
Different Clinical Presentation of 3 Children With Familial Hemophagocytic Lymphohistiocytosis With 2 Novel Mutations
Akyol S; Ozcan A; Sekine T; Chiang SCC; Yilmaz E; Karakurkcu M; Patiroglu T; Bryceson Y; Unal E
Article: CELL. 2020;183(1):158-168.e14
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19
Sekine T; Perez-Potti A; Rivera-Ballesteros O; Stralin K; Gorin J-B; Olsson A; Llewellyn-Lacey S; Kamal H; Bogdanovic G; Muschiol S; Wullimann DJ; Kammann T; Emgard J; Parrot T; Folkesson E; Rooyackers O; Eriksson LI; Henter J-I; Sonnerborg A; Allander T; Albert J; Nielsen M; Klingstrom J; Gredmark-Russ S; Bjorkstrom NK; Sandberg JK; Price DA; Ljunggren H-G; Aleman S; Buggert M
Article: SCIENCE IMMUNOLOGY. 2020;5(51):eabe1670
MAIT cell activation and dynamics associated with COVID-19 disease severity
Parrot T; Gorin J-B; Ponzetta A; Maleki KT; Kammann T; Emgard J; Perez-Potti A; Sekine T; Rivera-Ballesteros O; Gredmark-Russ S; Rooyackers O; Folkesson E; Eriksson LI; Norrby-Teglund A; Ljunggren H-G; Bjorkstrom NK; Aleman S; Buggert M; Klingstrom J; Stralin K; Sandberg JK
Article: SCIENCE IMMUNOLOGY. 2020;5(49):eaba7918
TOX is expressed by exhausted and polyfunctional human effector memory CD8⁺ T cells
Sekine T; Perez-Potti A; Son N; Gorin J-B; Wu VH; Gostick E; Llewellyn-Lacey S; Hammer Q; Falck-Jones S; Vangeti S; Yu M; Smed-Sorensen A; Gaballa A; Uhlin M; Sandberg JK; Brander C; Nowak P; Goepfert PA; Price DA; Betts MR; Buggert M
Article: MOLECULAR & CELLULAR PROTEOMICS. 2020;19(5):871-883
Identification of an Unconventional Subpeptidome Bound to the Behçet's Disease-associated HLA-B*51:01 that is Regulated by Endoplasmic Reticulum Aminopeptidase 1 (ERAP1).
Chen L; Shi H; Koftori D; Sekine T; Nicastri A; Ternette N; Bowness P
Article: NATURE GENETICS. 2019;51(7):1082-1091
A genetics-led approach defines the drug target landscape of 30 immune-related traits
Fang H; Beckmann G; Bountra C; Bowness P; Burgess-Brown N; Carpenter L; Chen L; Damerell D; Egner U; Fujii R; Howe T; Jakobsson P-J; Katopodis A; Knight JC; Marsden BD; De Martino J; Matthias G; McVean G; Mueller-Fahrnow A; Malarstig A; O'Callaghan CA; Ostermann N; Paez-cortez JR; Peeters PJ; Prinz F; Soulard P; Sundstrom M; Yabuki C; Vlach J; De Wolf H; Knezevic B; Burnham KL; Osgood J; Sanniti A; Lara AL; Kasela S; De Cesco S; Wegner JK; Handunnetthi L; McCann FE; Sekine T; Brennan PE; Sundstrom Y; Milani L; Berg L; Gohlmann HW; Fairfax BP
Article: SCIENTIFIC REPORTS. 2018;8(1):15645
Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases
Hammitzsch A; Chen L; de Wit J; Al-Mossawi MH; Ridley A; Sekine T; Simone D; Doig K; Skapenko A; Bowness P
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2344
Human NK Cells Develop an Exhaustion Phenotype During Polar Degranulation at the Aspergillus fumigatus Hyphal Synapse
Santiago V; Rezvani K; Sekine T; Stebbing J; Kelleher P; Armstrong-James D
Article: FRONTIERS IN IMMUNOLOGY. 2018;9:2444
Donor NKG2C Copy Number: An Independent Predictor for CMV Reactivation After Double Cord Blood Transplantation.
Cao K; Marin D; Sekine T; Rondon G; Zhao W; Smith NT; Daher M; Wang Q; Li L; Saliba RM; Pingali R; Popat U; Hosing C; Olson A; Oran B; Basar R; Mehta RS; Champlin R; Shpall EJ; Rezvani K
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(3):620-625
miR-10b-5p is a novel Th17 regulator present in Th17 cells from ankylosing spondylitis.
Chen L; Al-Mossawi MH; Ridley A; Sekine T; Hammitzsch A; de Wit J; Simone D; Shi H; Penkava F; Kurowska-Stolarska M; Pulyakhina I; Knight JC; Kim TJ; Bowness P
Article: BLOOD. 2016;128(24):2819-2823
KIR gene haplotype: an independent predictor of clinical outcome in MDS patients.
Stringaris K; Marin D; Barrett AJ; Hills R; Sobieski C; Cao K; Saltarrelli JG; Daher M; Shaim H; Smith N; Linch D; Gale R; Allen C; Sekine T; Mehta R; Champlin R; Shpall EJ; Kantarjian H; Garcia-Manero G; Rezvani K
Article: BLOOD. 2016;128(10):1346-1361
IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation.
Sarvaria A; Basar R; Mehta RS; Shaim H; Muftuoglu M; Khoder A; Sekine T; Gokdemir E; Kondo K; Marin D; Daher M; Alousi AM; Alsuliman A; Liu E; Oran B; Olson A; Jones RB; Popat U; Hosing C; Champlin R; Shpall EJ; Rezvani K
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2016;185(2):239-251
Latent cytomegalovirus infection enhances anti-tumour cytotoxicity through accumulation of NKG2C+ NK cells in healthy humans.
Bigley AB; Rezvani K; Shah N; Sekine T; Balneger N; Pistillo M; Agha N; Kunz H; O'Connor DP; Bollard CM; Simpson RJ
Article: BLOOD. 2016;128(2):297-312
Specific combinations of donor and recipient KIR-HLA genotypes predict for large differences in outcome after cord blood transplantation
Sekine T; Marin D; Cao K; Li L; Mehta P; Shaim H; Sobieski C; Jones R; Oran B; Hosing C; Rondon G; Alsuliman A; Paust S; Andersson B; Popat U; Kebriaei P; Muftuoglu M; Basar R; Kondo K; Nieto Y; Shah N; Olson A; Alousi A; Liu E; Sarvaria A; Parmar S; Armstrong-James D; Imahashi N; Molldrem J; Champlin R; Shpall EJ; Rezvani K
Article: LEUKEMIA. 2016;30(4):800-811
The TGF-β/SMAD pathway is an important mechanism for NK cell immune evasion in childhood B-acute lymphoblastic leukemia.
Rouce RH; Shaim H; Sekine T; Weber G; Ballard B; Ku S; Barese C; Murali V; Wu M-F; Liu H; Shpall EJ; Bollard CM; Rabin KR; Rezvani K
Journal article: BLOOD. 2015;126(23):1709
The CXCR4/STAT3/IL-10 Pathway Controls the Immunoregulatory Function of Chronic Lymphocytic Leukemia (CLL) and Can be Modulated By Lenalidomide
Shaim H; Estrov Z; Sekine T; Kondo K; Ruvolo PP; Thompson P; Sarvaria A; Muftuoglu M; Imahashi N; Liu E; Sobieski C; Wierda W; Keating MJ; Shah N; Hosing CM; Alsuliman A; Basar R; Ferrajoli A; Shpall EJ; Rezvani K
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2015;49:59-65
Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells. Part II: impact of latent cytomegalovirus infection and catecholamine sensitivity.
Bigley AB; Rezvani K; Pistillo M; Reed J; Agha N; Kunz H; O'Connor DP; Sekine T; Bollard CM; Simpson RJ
Journal article: JOURNAL OF CLINICAL ONCOLOGY. 2015;33(15_suppl):7001
Association between KIR genes and risk of MDS.
Daher M; Sobieski C; Marin D; Sekine T; Shpall EJ; Champlin RE; Kantarjian HM; Garcia-Manero G; Rezvani K
Article: BLOOD. 2014;124(13):2034-2045
Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD
Khoder A; Sarvaria A; Alsuliman A; Chew C; Sekine T; Cooper N; Mielke S; de Lavallade H; Muftuoglu M; Curbelo IF; Liu E; Muraro PA; Alousi A; Stringaris K; Parmar S; Shah N; Shaim H; Yvon E; Molldrem J; Rouce R; Champlin R; McNiece I; Mauri C; Shpall EJ; Rezvani K
Article: BRAIN, BEHAVIOR, AND IMMUNITY. 2014;39:160-171
Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells.
Bigley AB; Rezvani K; Chew C; Sekine T; Pistillo M; Crucian B; Bollard CM; Simpson RJ
Article: HAEMATOLOGICA. 2014;99(5):836-847
Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia
Stringaris K; Sekine T; Khoder A; Alsuliman A; Razzaghi B; Sargeant R; Pavlu J; Brisley G; de Lavallade H; Sarvaria A; Marin D; Mielke S; Apperley JF; Shpall EJ; Barrett AJ; Rezvani K
Journal article: TRANSPLANTATION AND CELLULAR THERAPY. 2014;20(2):s55
Immunoregulatory B Cells Are Enriched within Transitional and IgM Memory B Cell Subsets in Healthy Donors but Are Reduced and Functionally Impaired in Patients with Chronic Graft-Versus-Host Disease
Sarvaria A; Khoder A; Alsuliman A; Chew C; Sekine T; Cooper N; de Lavallade H; Muftuoglu M; Yvon E; Hamdi A; Alousi AM; St. John L; Marin D; Stringaris K; Liu E; Molldrem J; Shah N; Parmar S; McNiece I; Champlin RE; Shpall EJ; Rezvani K
Journal article: BLOOD. 2013;122(21):4478
B Cell With Regulatory Function Are Enriched Within Transitional and IgM Memory B Cell Subsets In Healthy Donors But Are Reduced and Functionally Impaired In Patients With Chronic Graft-Versus-Host Disease
Sarvaria A; Khoder A; Alsuliman A; Chew C; Sekine T; Cooper N; de Lavallade H; Muftuoglu M; Yvon E; Hamdi A; Alousi A; St. John LS; Marin D; Stringaris K; Liu E; Molldrem JJ; Shah N; Parmar S; McNiece IK; Champlin RE; Shpall EJ; Rezvani K
Journal article: BLOOD. 2013;122(21):2024
CD161 Expression Identifies a Distinct Subset Of Drug-Effluxing Viral-Specific Memory CD4+ T Cells That Preferentially Survive Cytotoxic Chemotherapy
Muftuoglu M; Alsuliman A; Khoder A; Ahn Y-O; Liu E; Chew C; Hamdi A; Sekine T; Sarvaria A; Cooper N; de Lavallade H; Marin D; Stringaris K; Verneris MR; Shpall EJ; Rezvani K
Journal article: BLOOD. 2013;122(21):1397
Natural Killer Cells In Pediatric Acute Lymphoblastic Leukemia Patients At Diagnosis Demonstrate An Inhibitory Phenotype and Reduced Cytolytic Capacity
Rouce RH; Sekine T; Weber G; Chew C; Rezvani K; Bollard CM; Rabin KR
Article: BLOOD. 2013;122(2):227-238
Tyrosine kinase inhibitors impair B-cell immune responses in CML through off-target inhibition of kinases important for cell signaling
de Lavallade H; Khoder A; Hart M; Sarvaria A; Sekine T; Alsuliman A; Mielke S; Bazeos A; Stringaris K; Ali S; Milojkovic D; Foroni L; Chaidos A; Cooper N; Gabriel I; Apperley J; Belsey S; Flanagan RJ; Goldman J; Shpall EJ; Kelleher P; Marin D; Rezvani K
Journal article: TRANSPLANTATION AND CELLULAR THERAPY. 2013;19(2):s139-s140
Evidence for Expansion of CD21− B Cells with an Exhausted Phenotype in Patients with Active Chronic GvHD
Khoder A; Alsuliman A; Sekine T; Stringaris K; de Lavallade H; Sarvaria A; MacDonald D; Apperley JF; Rezvani K
Journal article: TRANSPLANTATION AND CELLULAR THERAPY. 2013;19(2):s134
Stem-Like Characteristics in a Subset of CD161 Expressing Human Memory CD4+ T Cells Facilitates Their Survival After Chemotherapy
Alsuliman A; Khoder A; Stringaris K; Sekine T; Razzaghi B; de Lavallade H; Sarvaria A; Marin D; Rezvani K
Article: PLOS ONE. 2013;8(10):e76781
Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.
Shah N; Martin-Antonio B; Yang H; Ku S; Lee DA; Cooper LJN; Decker WK; Li S; Robinson SN; Sekine T; Parmar S; Gribben J; Wang M; Rezvani K; Yvon E; Najjar A; Burks J; Kaur I; Champlin RE; Bollard CM; Shpall EJ
Journal article: BLOOD. 2011;118(21):3753
Chronic Myeloid Leukemia Patients on Tyrosine Kinase Inhibitor Have Normal T Cell Responses to Vaccination but An Impaired IgM Humoral Response Associated with Loss of Discrete Memory B Cell Subsets,
de Lavallade H; Marin D; Hart M; Sekine T; Gabriel I; Alsuliman A; Bazeos A; Khoder A; Stringaris K; Khorashad J; Cooper N; Milojkovic D; Foroni L; Szydlo RM; Chaidos A; Ibrahim AR; Bua M; Goldman JM; Apperley JF; Kelleher WP; Rezvani K
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(5):632-639
Humoral and cellular immunity to primary H1N1 infection in patients with hematologic malignancies following stem cell transplantation.
Garland P; de Lavallade H; Sekine T; Hoschler K; Sriskandan S; Patel P; Brett S; Stringaris K; Loucaides E; Howe K; Marin D; Kanfer E; Cooper N; Macdonald D; Rahemtulla A; Atkins M; Danga A; Milojkovic D; Gabriel I; Khoder A; Alsuliman A; Apperley J; Rezvani K
Article: HAEMATOLOGICA. 2011;96(2):307-314
Repeated vaccination is required to optimize seroprotection against H1N1 in the immunocompromised host.
de Lavallade H; Garland P; Sekine T; Hoschler K; Marin D; Stringaris K; Loucaides E; Howe K; Szydlo R; Kanfer E; Macdonald D; Kelleher P; Cooper N; Khoder A; Gabriel IH; Milojkovic D; Pavlu J; Goldman JM; Apperley JF; Rezvani K
Journal article: BLOOD. 2010;116(21):677
2009 Pandemic Influenza A H1N1 Vaccination In the Patients with Hematologic Malignancies: Requirement for Repeated Dosing to Optimize Seroprotection
de Lavallade H; Garland PL; Sekine T; Hoschler K; Marin D; Stringaris K; Loucaides E; Howe K; Szydlo RM; Kanfer EJ; McDonald D; Kelleher P; Cooper N; Khoder A; Gabriel IH; Alsuliman A; Milojkovic D; Pavlu J; Goldman JM; Apperley JF; Rezvani K
Journal article: BLOOD. 2010;116(21):1697
A Distinct Signature of Natural Killer Cell KIR Gene Frequencies In Secondary AML Compared with De Novo AML and Normal Controls
Stringaris K; Barrett AJ; Hills R; Linch DC; Gale R; Allen C; Garland P; Sargent R; de Lavallade H; Alsuliman A; Khoder A; Gabriel IH; Sekine T; Burnett A; Rezvani K; Apperley JF
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All other publications

Preprint: BIORXIV. 2024
CD4+ tissue resident memory Th17 cells drive IL-17A-mediated joint pathology in Spondyloarthritis
Liu F; Shi H; Turner JD; Anscombe R; Sekine T; Hammitzsch A; Agarwal D; Mahony C; Chen J; Kendrick B; Du D; Tong Q; Duan L; Dooley K; Fang H; Korsunsky I; Madhu R; Cribbs AP; consortium C; Friedrich M; Marsden BD; Chen Y-L; Ogg G; Adams A; Chen W; Leonardo S; McCann FE; Buckley C; Rooney T; Freeman T; Uhlig HH; Dendrou C; Croft A; Filer A; Bowness P; Chen L
Review: ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY. 2024;1448:129-144
CD8+ T Cell Biology in Cytokine Storm Syndromes.
Sekine T; Galgano D; Casoni GP; Meeths M; Cron RQ; Bryceson YT
Letter: PEDIATRIC BLOOD AND CANCER. 2022;69(5):e29487
Childhood Kaposi sarcoma related to hypomorphic severe combined immunodeficiency caused by a novel CORO1A mutation
Muleviciene A; Sekine T; Zondag T; Bryceson YT; Tesi B; Rascon J
Review: SEMINARS IN IMMUNOLOGY. 2021;55:101505
T cell immunity to SARS-CoV-2
Niessl J; Sekine T; Buggert M
Book chapter: CYTOKINE STORM SYNDROME. 2019;p. 141-161
CD8+ T Cell Biology in Cytokine Storm Syndromes
Sekine T; Galgano D; Casoni GP; Meeths M; Bryceson YT
Letter: TURKISH JOURNAL OF HAEMATOLOGY. 2018;35(3):200-202
First Report of an SH2D1A Mutation Associated with X-Linked Lymphoproliferative Disease in Turkey
Kesici S; Keskin EY; Chiang SCC; Kasapkara CS; Sekine T; Akcaboy M; Fettah A; Bryceson YT

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